Research at Oslo University Hospital

 

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

 

Latest news

CanCell – a new Centre of Excellence – will reprogram cancer cells

 

“Centre for Cancer Cell Reprogramming”, affiliated with the Institute of Clinical Medicine at University of Oslo, has been funded by the Research Council of Norway as a new Centre of Excellence.

 
 

New group leader at the Institute for Cancer Research:

Jørgen Wesche appointed group leader for the Mesenchymal Cancer Biology Group at the Department of Tumor Biology

 
Jørgen Wesche
Jørgen Wesche

Jørgen Wesche earned his PhD in Sjur Olsnes's group in 2001, studying intracellular transport and membrane translocation. During his postdoctoral training, spending some time at Institute Curie in Paris, he has changed his focus towards problems with more translational relevance, specializing in live cell imaging, fibroblast growth factor receptor (FGFR) signaling and importance of FGFR in cell migration/invasion. Aberrations in FGFR signaling are found in several types of sarcoma and that´s the main reason way Jørgen started to get interested in sarcoma biology and treatment. He has several exciting ideas on how to further develop his research into more translational/clinical relevance.

 
 

King Olav V´s Cancer Research Prize to Per O. Seglen

Prestigious research prize from the Norwegian Cancer Society to pioneer in autophagy research

 
Per O. Seglen (left) and 2016 Nobel laureate Yoshinori Ohsumi
Per O. Seglen (left) and 2016 Nobel laureate Yoshinori Ohsumi

Professor Per Ottar Seglen, formerly head of the Proteomics & Mammalian Cell Biology Section at the Institute for Cancer Research, OUH, currently a guest researcher at NCMM, has been awarded the prestigious King Olav V’s prize for Cancer Research 2017.

The award, formally announced by the Norwegian Cancer Society today, is recognized as one of the Norwegian cancer research community’s most respected prizes. Professor Seglen has been awarded the prize in recognition of his ground-breaking research into autophagic-lysosomal protein degradation and its relationship to cancer.

The prize will be officially presented by King Harald V, on behalf of the Cancer Society, at a special ceremony on 6 June 2017. The prize is NOK 1 million.

 
 

Announcement:

Course in Health Economics and Economic Evaluation

 

Are you concerned about costs, resource use, health-related quality of life and economic evaluation?

The Health Economics Team from the Research Support Services at Oslo University Hospital invites you to participate in an annual course in health economics 14th of June 2017. The course will cover basic principles of health economic evaluation. We have also prepared a quiz to enable you to test what you have learned.

Welcome!
Team health economics

 
 

OUH research seminar, Monday, March 6th 14:30

Health after transplantation

 

Welcome to the next Oslo University Hospital research seminar entitled "Health after transplantation".

Time: Monday, March 6th, 2017, at 14:30 – 16:00.
Place: Red Auditorium, Rikshospitalet, Sognsvannsveien 20, Oslo.

 
 

NORMENT study published in Nature Neuroscience:

Early signs of mental illness in the developing brain

 
Tobias Kaufmann (left) and Lars T. Westlye
Tobias Kaufmann (left) and Lars T. Westlye

Like a fingerprint, the connections of the human brain render us distinct from one another. In a study published in the February 20th issue of Nature Neuroscience (journal impact factor 16.7), entitled "Delayed stabilization and individualization in connectome development are related to psychiatric disorders", researchers at NORMENT reveal that such a unique, fingerprint-like pattern evolves during development and is sensitive to mental health. First and last authors are Tobias Kaufmann and Lars T. Westlye (photo).
The study has already gained attention, and the results have been discussed in articles published in Science Daily and Medical News Today.

 
 

Critical article on doping and drug testing published in EMBO reports

 
First author Erik Boye (left) and Tore Skotland
First author Erik Boye (left) and Tore Skotland

Sports play an important role in our society. Four Norwegian researchers, two from OUS, have published an article in EMBO reports where they discuss problems occurring in the testing of athletes for doping.
The authors (E. Boye and T. Skotland from OUS (photo), J. Nissen-Meyer from UiO and B. Østerud, UiTø) describe how the World Antidoping Agency (WADA) pretends never to make mistakes and is resistant to any form of discussion with other scientists. This attitude creates false positives and athletes are being sanctioned while innocent, with dramatic consequences for the individual. It is argued that both the technological, ethical and legal procedures should be revised and an independent body should monitor the function of WADA.

 
 

Updated: honoured with "Preview" article in Developmental Cell

Findings from Rusten group published in Nature on microenvironmental autophagy draw nationwide attention

 
First author Nadja Katheder and senior author Tor Erik Rusten
First author Nadja Katheder and senior author Tor Erik Rusten

Nadja Katheder and collaborators in the lab of Tor Erik Rusten, the Department of Molecular Cell Biology, and CCB has published an article entitled "Microenvironmental autophagy supports tumor growth", in an advanced online publication 11th of January in the journal Nature (journal impact factor 41.46). 
The findings have been subject to news coverage by the Norwegian national broadcasting corporation (NRK).
The prestigious journal "Developmental Cell" has recently published an article in their "Previews" section, entitled "Breaking Down Neighbors to Fuel Tumorigenesis". Here, the authors discuss how the work of Katheder and colleagues "opens new avenues for understanding and manipulating cancers through cell-cell communication."

 
 

"Science" article from Johanna Olweus's group highlighted by editorial in New England Journal of Medicine

 
Figure from the editorial
Figure from the editorial

The article "Targeting of cancer neoantigens with donor-derived T cell receptor repertoires" by Erlend Strønen et al, published in Science in June 2016, is highlighted by an editorial in the "Clinical Implications of Basic Research" section in the Feb 2nd edition of New England Journal of Medicine.

The editorial is entitled "The Antigenicity of the Tumor Cell — Context Matters".

 
 

Theis Tønnessen appointed "Scientist of the Month" by "Helse Sør-Øst" for January 2017

 
Theis Tønnessen
Theis Tønnessen

The South-Eastern Norway Regional Health Authority (Helse Sør-Øst) aims to profile ongoing excellent research in the region by calling special attention to a "Scientist of the Month".

For the month of January 2017, this honour went to Theis Tønnessen, leader of the "Genetics of autoimmunity and cancer" group at the Department of Medical Genetics at the Division of Diagnostics and Intervention, Oslo University Hospital.