New insight into late effects after cancer treatment presented by the Norwegian Cancer Society

 
Cecilie Kiserud
Cecilie Kiserud

The Norwegian Cancer Society present research they support regularly, in a popular science form, and they have recently published a feature article on late effects after cancer treatment.
Cecilie Kiserud, head of the National Advisory Unit on Late Effects after Cancer Treatment at the Department of Oncology, has been interviewed about their research activites and new insight into life after cancer, a field that has gained more attention the recent years.


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OUH research seminar, Tuesday, April 25th 10:00 - 15:45

Immunotherapy for Cancer

 

Welcome to the next Oslo University Hospital research seminar entitled "Immunotherapy for Cancer".

Time: Tuesday, April 25th, 2017, at 10:00-15:45.
Place: Store Auditorium, Rikshospitalet, Sognsvannsveien 20, Oslo.

Note that there is a limited number of seats. Please sign up at: 
http://norwegianimmunology.org/day-of-immunology-2/


Programme  
 
 

Study on replication fork stability from Skarstad group published in Nucleic Acids Research

 
First authors Ida B. Pedersen (left) and Emily Helgesen
First authors Ida B. Pedersen (left) and Emily Helgesen

Replication forks must be stabilized in order to avoid DNA breakage and recombination. In a study recently published in Nucleic Acids Research entitled “SeqA structures behind Escherichia coli replication forks affect replication elongation and restart mechanisms“ researchers in the Skarstad group show that double strand breaks are generated in the absence of fork-trailing SeqA structures and that cells then have lost the ability to perform direct (RecA-independent) restart of replication forks. The two first authors are Ida Benedikte Pedersen and Emily Helgesen (photo).


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OUH research seminar, Monday, April 3rd 14:30

Innovation to Finance Research

 

Welcome to the next Oslo University Hospital research seminar entitled "Innovation to Finance Research".

Time: Monday, April 3rd, 2017, at 14:30 – 16:00.
Place: Green Auditorium, Rikshospitalet, Sognsvannsveien 20, Oslo.


Programme  
 
 

NORMENT researchers contribute to PLOS Medicine article on genetic assessment of age-associated Alzheimer's disease risk

 
Ole Andreassen, Centre Director NORMENT
Ole Andreassen, Centre Director NORMENT

Researchers from the NORMENT KG Jebsen Centre for Psychosis Research at OUS and UiO have participated in a large international consortium to develop a novel tool for genetic risk prediction in Alzheimer’s disease. This is based on a long standing collaboration between the statistical genetics team at NORMENT and the University of California San Diego (UCSD) Center for Translational Imaging and Precision Medicine. The scientists are now working to improve the method for mental illness applications.
The results have recently been published in Plos Medicine (journal impact factor 13.6). The study has received widespread attention, including articles in major international newspapers.


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The AACR-WICR Friend Lectureship presented to Anne-Lise Børresen-Dale

 
A-L. Børresen-Dale
A-L. Børresen-Dale

The American Association for Cancer Research (AACR) - Women in Cancer Research (WICR) Charlotte Friend Memorial Lectureship was established in 1998 in honour of renowned virologist and discoverer of the Friend virus, Dr. Charlotte Friend. The WICR Friend Lectureship is presented to an outstanding scientist who has made meritorious contributions to the field of cancer research and who has, through leadership or by example, furthered the advancement of women in science.
Anne-Lise Børresen-Dale, professor emerita at the Department of Cancer Genetics at the Institute for Cancer Research, OUH, has been chosen as the 20th Annual Award Recipient. Her award lecture will be held on April 3rd in the Washington Convention Center.


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CanCell – a new Centre of Excellence – will reprogram cancer cells

 

“Centre for Cancer Cell Reprogramming”, affiliated with the Institute of Clinical Medicine at University of Oslo, has been funded by the Research Council of Norway as a new Centre of Excellence.


Read about the new centre  
 
 

New group leader at the Institute for Cancer Research:

Jørgen Wesche appointed group leader for the Mesenchymal Cancer Biology Group at the Department of Tumor Biology

 
Jørgen Wesche
Jørgen Wesche

Jørgen Wesche earned his PhD in Sjur Olsnes's group in 2001, studying intracellular transport and membrane translocation. During his postdoctoral training, spending some time at Institute Curie in Paris, he has changed his focus towards problems with more translational relevance, specializing in live cell imaging, fibroblast growth factor receptor (FGFR) signaling and importance of FGFR in cell migration/invasion. Aberrations in FGFR signaling are found in several types of sarcoma and that´s the main reason way Jørgen started to get interested in sarcoma biology and treatment. He has several exciting ideas on how to further develop his research into more translational/clinical relevance.


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King Olav V´s Cancer Research Prize to Per O. Seglen

Prestigious research prize from the Norwegian Cancer Society to pioneer in autophagy research

 
Per O. Seglen (left) and 2016 Nobel laureate Yoshinori Ohsumi
Per O. Seglen (left) and 2016 Nobel laureate Yoshinori Ohsumi

Professor Per Ottar Seglen, formerly head of the Proteomics & Mammalian Cell Biology Section at the Institute for Cancer Research, OUH, currently a guest researcher at NCMM, has been awarded the prestigious King Olav V’s prize for Cancer Research 2017.

The award, formally announced by the Norwegian Cancer Society today, is recognized as one of the Norwegian cancer research community’s most respected prizes. Professor Seglen has been awarded the prize in recognition of his ground-breaking research into autophagic-lysosomal protein degradation and its relationship to cancer.

The prize will be officially presented by King Harald V, on behalf of the Cancer Society, at a special ceremony on 6 June 2017. The prize is NOK 1 million.


Read about Seglen's research (updated)  
 
 

OUH research seminar, Monday, March 6th 14:30

Health after transplantation

 

Welcome to the next Oslo University Hospital research seminar entitled "Health after transplantation".

Time: Monday, March 6th, 2017, at 14:30 – 16:00.
Place: Red Auditorium, Rikshospitalet, Sognsvannsveien 20, Oslo.


Read programme  
 
 

NORMENT study published in Nature Neuroscience:

Early signs of mental illness in the developing brain

 
Tobias Kaufmann (left) and Lars T. Westlye
Tobias Kaufmann (left) and Lars T. Westlye

Like a fingerprint, the connections of the human brain render us distinct from one another. In a study published in the February 20th issue of Nature Neuroscience (journal impact factor 16.7), entitled "Delayed stabilization and individualization in connectome development are related to psychiatric disorders", researchers at NORMENT reveal that such a unique, fingerprint-like pattern evolves during development and is sensitive to mental health. First and last authors are Tobias Kaufmann and Lars T. Westlye (photo).
The study has already gained attention, and the results have been discussed in articles published in Science Daily and Medical News Today.


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Breakfast lecture in Oslo Wednesday March 1st:

Arne Klungland talks about embryo research

 
Arne Klungland
Arne Klungland

Professor Arne Klungland, section head at the Department of Microbiology, will hold a lecture on the subject of embryonic development during a breakfast meeting held by the The Norwegian Biotechnology Advisory Board (Bioteknologirådet).

Klungland is the leader of several research projects aiming at understanding the first few days during embryonic development, and gain insight into the early development of various diseases.

Time: March 1st 8.15-9.30 AM (breakfast from 8.15, lecture starts 8.30)
Place: Håndverkeren, Galleriet (1st floor)


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Invitation to seminar March 2nd 12:00

Thon Awards seminars 2017

 
From left: Amiry-Moghaddam, Zetterberg, Hoeijmakers and Bogdanovic
From left: Amiry-Moghaddam, Zetterberg, Hoeijmakers and Bogdanovic

This is a unique seminar with the Olav Thon Foundation's International Research Awardees for Mathematics and Natural Science and Medicine 2017.

The first talk will be held by International Research Prize winner Jan Hoeijmakers from Erasmus University Rotterdam, who is one of the most significant scientists in molecular genetics of our time. 

Further talks will be held by Research Awardee Mahmood Amiry-Moghaddam on Parkinson's disease, and by Research Awardees Henrik Zetterberg and Nenad Bogdanovic on Alzheimer research.

Time and place: March 2nd, 2017 12:00 PM - 03:00 PM, Runde Auditorium R-105 at Domus Medica, Gaustad

Deadline for registration: February 23rd


More information and link to registration page  
 
 

Critical article on doping and drug testing published in EMBO reports

 
First author Erik Boye (left) and Tore Skotland
First author Erik Boye (left) and Tore Skotland

Sports play an important role in our society. Four Norwegian researchers, two from OUS, have published an article in EMBO reports where they discuss problems occurring in the testing of athletes for doping.
The authors (E. Boye and T. Skotland from OUS (photo), J. Nissen-Meyer from UiO and B. Østerud, UiTø) describe how the World Antidoping Agency (WADA) pretends never to make mistakes and is resistant to any form of discussion with other scientists. This attitude creates false positives and athletes are being sanctioned while innocent, with dramatic consequences for the individual. It is argued that both the technological, ethical and legal procedures should be revised and an independent body should monitor the function of WADA.


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OUH research seminar, Monday, February 6th 14:30

Early phase drug development: From idea to concept

 

Welcome to the next Oslo University Hospital research seminar entitled "Early phase drug development: From idea to concept".

Time: Monday, February 6th, 2017, at 14:30 – 16:00.
Place: Blue Auditorium, Rikshospitalet, Sognsvannsveien 20, Oslo.


Programme  
 
 

"Science" article from Johanna Olweus's group highlighted by editorial in New England Journal of Medicine

 
Figure from the editorial
Figure from the editorial

The article "Targeting of cancer neoantigens with donor-derived T cell receptor repertoires" by Erlend Strønen et al, published in Science in June 2016, is highlighted by an editorial in the "Clinical Implications of Basic Research" section in the Feb 2nd edition of New England Journal of Medicine.

The editorial is entitled "The Antigenicity of the Tumor Cell — Context Matters".


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Oslo Kongressenter, February 09-10 2017

6th National Conference on Stroke

 

Every year 16.000 Norwegians are stricken with stroke, and more than 60.000 have previously had one or more strokes. It is therefore important that the foremost Norwegian experts in the field gather in order and be updated on what is new within preventive, acute treatment and rehabilitation from stroke.

David Russell from the Department of Neurology at the Division of Surgery and Clinical Neuroscience at Oslo University Hospital welcomes participants to the 6th national conference on stroke - "den 6. Nasjonale konferanse om Hjerneslag".


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Theis Tønnessen appointed "Scientist of the Month" by "Helse Sør-Øst" for January 2017

 
Theis Tønnessen
Theis Tønnessen

The South-Eastern Norway Regional Health Authority (Helse Sør-Øst) aims to profile ongoing excellent research in the region by calling special attention to a "Scientist of the Month".

For the month of January 2017, this honour went to Theis Tønnessen, leader of the "Genetics of autoimmunity and cancer" group at the Department of Medical Genetics at the Division of Diagnostics and Intervention, Oslo University Hospital.


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OUH research seminar, Thursday, January 26th

Sepsis: New definitions and future research

 

Welcome to the next Oslo University Hospital research seminar entitled "Sepsis: New definitions and future research".

Time: Monday, Thursday, January 26th, 2017, at 13:45 – 15:15.
Place: Red Auditorium, Rikshospitalet, Sognsvannsveien 20, Oslo.


Programme  
 
 

Announcement: Nominating outstanding scientists, closing date March 1st:

Excellent Researcher Award and Early Career Award 2017

 
From the 2016 ceremony: Pål Aukrust (Excellent Researcher Award) flanked by Therese Seierstad og Espen Melum (both Early Career Awards)
From the 2016 ceremony: Pål Aukrust (Excellent Researcher Award) flanked by Therese Seierstad og Espen Melum (both Early Career Awards)

 Oslo University Hospital hereby announce research awards in the following two catagories for 2017:

  • Excellent Researcher Award (one prize, 300.000 NOK)
  • Early Career Award (two prizes of 150.000 NOK each)

The candidate must be employed by Oslo University Hospital or University of Oslo, and be a member of a research group at Oslo University Hospital/University of Oslo.


Evaluation criteria and nomination form  
 
Previous news articles
 Antimicrobial resistance - how bad is the situation in the world of virus, fungus and mycoplasma? OUH research seminar, Monday, January 16th 
 Findings from Rusten group published in Nature on microenvironmental autophagy draw nationwide attention Updated: honoured with "Preview" article in Developmental Cell  
 Commentary article from Arne Klungland in Nature Methods on epitranscriptome analysis  
 Research funding from South-Eastern Norway Regional Health Authority for 2017  
 Educating future cancer researchers from Ullern high school  
 Novel cancer immunotherapy published in Cancer Research, with cover illustration  
 Oslo University Hospital research seminar: Exercise and Brain Energy Monday, November 21st, 2016, at 14:30 – 16:10 
 Oslo University Hospital research seminar: The World of Immunology Thursday November 17th at 10:00-15:00 
 Oslo University Hospital researchers receive 77.3 mill NOK from the Norwegian Cancer Society Results of Open Call 2016: 
 Human lung macrophages are self-maintained for several years  
 Announcement of research funding from the Norwegian Cancer Society Gathering Friday October 28th 10-12 at UiO: 
 Dag Berild awarded the "Akademikerprisen" for his work on antibiotic resistance  
 50 years anniversary Institute for Surgical Research Thursday 13 October 2016 at 10.15 AM 
 Making therapeutic antibodies from scratch  
 Lina Prasmickaite's work presented in popularised form  
 Medical imaging in cardiac research Oslo University Hospital research seminar Monday October 10th 
 Focus on personalized medicine and the MetAction study  
 Histone marks regulate maternal-to-zygotic transition Paper from Dahl/Klungland published in the Sep 22nd issue of Nature 
 Turning the tide of antimicrobial resistance National kick-off, Tuesday September 13th 
 Marina Vietri interviewed for major Italian research web portal  
 OUH researchers publish groundbreaking computer tools for cell biology research in Nature Methods  
 POLE proofreading domain mutations identify a subset of immunogenic colorectal cancers with excellent prognosis  
 Clinical Cancer Research highlights biomarker paper from Lyng’s group  
 The Norwegian Cancer Genomics Consortium participates in international study of gene variants predisposing for cancer development.  
 Annuncement of research funding from South-East Norway regional health authority for 2017 Call for applications 2017 
 H.M. the King's Gold Medal to Marina Vietri  
 Oslo University Hospital has awarded 6 excellent articles for the second half-year of 2015  
 Atle Bjørnerud "Innovator of the Month" South-Eastern Norway Regional Health Authority brings attention to innovation: 
 Tomas Lindahl, Nobel Prize laureate 2015 Symposium at OUS, Rikshospitalet, 17. June 2016 13:00-15:30 
 The 2016 Excellent Research Awards to Pål Aukrust, Therese Seierstad and Espen Melum Oslo University Hospital honouring outstanding scientific work: 
 Strønen and Olweus publish article in Science on the use of donor immunity to target cancer  
 Håvard Danielsen and Erik Fosse receive Lighthouse project grants from the Norwegian Research Council  
 "Intelligent needle tracking using ultrasound imaging for improved minimally invasive interventions" supported by EU OUS scientists partners in project funded by HORIZON 2020 FAST TRACK TO INNOVATION 
 Discovery of biologically active small molecular compounds Oslo University Hospital research seminar Monday May 9th 
 Mapping somatic mutations in breast cancer whole genomes OUS scientists co-author Nature article: 
 Same, but different? Genetic analysis of five immune mediated diseases reveals molecular taxonomy of chronic inflammation  
 Immunotherapy for Cancer Day of Immunology Conference 2016 April 29 
 New guidelines for "Helse Sør-Øst" and "Kreftforeningen" applications Information meeting, Radiumhospitalet, Friday April 22nd 
 Ståle Nygård – Dept. of Core Facilities Institute seminar April 6th 
 Article published in Science Translational Medicine showing that cyclodextrin may reduce atherosclerosis attracts worldwide attention  
 The Fridtjof Nansen Award for Young Scientists for 2016 to Kyrre Eeg Emblem  
 Theodossiou and Berg funded by the Future and Emerging Technology (FET) program  
 King Olav V's cancer research prize for 2016 to Kjetil Taskén  
 Morgendagens medisin The Norwegian Inflammation Network seminar Wednesday March 16th 
 Microbiome Oslo University Hospital research seminar Monday March 14th 
 Liliane Christ identifies mechanism for regulation of daughter cell separation  
 NoPSC study of PSC gut microbiota published in Gut  
 Olav Thon Foundation's International Prize and Research Awardees 2016 Invitation to seminar March 3rd 12:00 
 Stephen H. Friend Norsk Hydro's Fond guest lecture March 10th 
 Ragnhild A. Lothe and Michael Bretthauer substantially supported by FRIPRO  
 Filming live cancer cells Camilla Raiborg's work presented in popularised form on forskning.no: 
 Elderly patients benefit from an early invasive strategy Heart study results recently published in Lancet attract attention: 
 Lorenz et al. published an extensive study investigating the genomic chaos in osteosarcoma  
 Personalized Cancer Care Symposium, Oslo, May 18-20, 2016 
 Åslaug Helland’s research on lung cancer presented by the Norwegian Cancer Society  
 Innovation projects funded by the Norwegian Cancer Society and Research Council  
 Medical imaging in cancer biology and personalized therapy Oslo University Hospital research seminar January 11th 
 Sandvig received INNO INDIGO grant for work with biodegradable nanoparticles  
 Work from Bjørås' group published in "Cell Report"  
 Research funding from South-Eastern Norway Regional Health Authority for 2016  
 AACR Recognizes Dr. Anne-Lise Børresen-Dale With 2015 Distinguished Lectureship in Breast Cancer Research  
 Erik Boye - an internationally renowned scientist retires  
 Oslo University Hospital has awarded 6 excellent articles for the first half-year of 2015  
 New PhD Andreas Hoff publishes testis cancer fusion genes in Cancer Research  
 Asta Juzeniene - Dept. of Radiation Biology Institute Seminar Wednesday 9th of December at 12:00 
 Findings regarding a novel non-genomic tamoxifen cytotoxic action published in ACS Chemical Biology  
 Tor Espen Thorvaldsen with cover story in Molecular Cancer Research  
 Oslo University Hospital researchers receive 92 mill NOK from the Norwegian Cancer Society  
 Ragnar Mørk legacy prize 2015 to Guro E. Lind Ceremony Friday November 20th 
 The first-in-man Phase I clinical trial of the EpCAM-targeting immunotoxin MOC31PE  
 Research on sonoactivatable nanoparticles funded by EuroNanoMed II ERA-NET program  
 Research on nanoparticle radiosensitizers funded by Euronanomed II ERA-NET program  
 PCI research funded by Euronanomed II ERA-NET program  
 Jørgen Wesche – Dept. of Molecular Cell Biology Institute Seminar Wednesday 4th of November at 12:00 
 New gold-standard for miRNA annotations published in Annual Reviews of Genetics  
 The Wonder of Stem Cells in Eye and Oral Regeneration Oslo University Hospital research seminar October 19th 
 Presenting the Young Academy of Norway  
 Prestigious award from the Research Council of Norway to Harald A. Stenmark Møbius 2015: 
 Review article from Sveen and co-workers on alternative splicing published in Oncogene  
 The Anders Jahre Senior Medical Prize to Ludvig Sollid  
 Award winner Erik Fosse presented in Uniforum The UiO Innovation Prize: 
 Two studies of PARP inhibition in malignant lymphocytes reveal differential phenotypical responses, DNA damage induction and repair during the cell cycle  
 Kaisa Haglund receives the Jahre prize for young medical researchers Recognition of outstanding scientific work: 
 Oslo Cancer Cluster Innovation Park officially opened  
 New English version of "The Research Handbook- from idea to publication" is available  
 Chronicle on personalised cancer medicine in Aftenposten  
 Preparing for the upcoming health calls for Horizon 2020 Training course August 25: 
 Novel method reveals new knowledge about G1-phase  
 H.M. The Kings Gold Medal to Sigrid Bratlie Thoresen  
 Llorente and coworkers report promising prostate cancer biomarkers in urinary exosomes  
 Microscopy infrastructure funded by the Norwegian Research Council  
 Innovation prize to Erik Fosse  
 Cover article on personalized cancer medicine and big data in META  
 Paper from OUS/CCB researchers dedicated commentary articles in both Nature and Science  
 What is the cost of a cancer patient's life? OUS research blog June 16th: 
 Annuncement of research funding from South-East Norway regional health authority for 2016 Call for applications 2016 
 The Department of Pathology receives funding for melanoma research through Horizon 2020 project.  
 Findings from the Skarstad group published in PLOS Genetics  
 A cancer cell on the move OUS research blog about endocytosis: 
 William Louch appointed "Scientist of the Month" by "Helse Sør-Øst" for May 2015