– 12.12.2024:The Christmas Party was celebrated with members of three research groups: Metabolomics, Mitogroup & Structure Biology.

 

– 02.12.2024: A seminar on below topics was given to the Institute for Clinical Biochemistry (IKB) by Barbora Piskláková:

• Diagnostic semi-automatic workflow for organic acidurias by LC-MS/MS (and also HILIC-MS/MS method for many other inherited metabolic disorders)
• LC-MS measurement of direct oral anticoagulants in patients with antiphospholipid syndrome and the comparison with routine methods used in hematology
• Enzyme activity testing of cytidine deaminase and deoxycytidne deaminase – important “deactivating” enzymes of anticancer drugs

 

– 26.11.2024: Some group members attended 'Metabomeeting 2024' in Liverpool, the UK. Two posters were presented by us:

• Piskláková et al., PCA to reveal non-adherence and non-analytical outliers using global metabolomics and lipidomics in clinical settings (Download)
• Guttorm et al., Global metabolomic profiling of tumor tissue and paired serum samples identifies biomarkers for response to pre-surgical FOLFIRINOX treatment of human pancreatic cancer (Download)

 

– 18.11.2024: The Joint Metabolomics and Proteomics Seminar was organized by the four sister Core Facilities at Oslo University Hospital (OUS) and the University of Oslo (UiO), led by Katja Elgstøen (Untargeted Metabolomics; OUS), Nasser Ezzatkhah Bastani (Targeted Metabolomics; UIO), Tuula Anneli Nyman (Proteomics; OUS) and Bernd Thiede (Proteomics; UIO). 

 

• The chair and the framework organizer: Katja Elgstøen
• The invited speakers: Bart Ghesquière (Katholieke Universiteit Leuven, Belgium), Steven Wilson (University of Oslo), Manuela Zucknick (Oslo Centre for Biostatistics and Epidemiology), Marcel Kwiatkowski (University of Innsbruck, Austria) and Olya Vvedenskaya (Lipotype, Germany)

 

– 14.11.2024: The group attended 'The Annual MBK Research Seminar' at Meet Ullevaal in Oslo. After an overview by the team leader (Katja), several members presented summaries of selected projects. 

 

– 31.10.2024: A discussion session following Nathalie’s presentation on her Master’s studies results. 

 

– 10.10.2024: The group had a fresh start with the "Metabolomics Club" in the presence of our new team members, Barbora and Aleš. Delicious food was prepared by our group leader, Katja :). 

 

– 07.10.2024: A seminar on "Clinical Applications of Lipidomics" was given to the Institute for Clinical Biochemistry (IKB) by Aleš Kvasnička, our new member.  

 

– 01.10.2024: We welcome Barbora Piskláková and Aleš Kvasnička, our new team members (Spesialingeniører). They will be with us for the next year.

 

– 23.09.2024: The group celebrated the last day of Sára Filipová's internship with a small farewell party and wished her all the best as she embarks on her next journey to her original institute, Palacky University in Czechia.

 

– 17.09.2024: Some group members attended "The 39th Nordic Congress in Clinical Chemistry" in Stockholm, Sweden. Our group leader, Katja Elgstøen, was an invited speaker for the plenary session titled “Clinical Metabolomics: A New Era for Laboratory Medicine”, organized by the Nordic Federation of Clinical Chemistry. 

• Katja Elgstøen, Global metabolomics – why and how

 

A poster was also presented by Tara Rolic and Sonia Distante:

• Rolic et al., A possible marker of disease progression in colorectal neoplasm: A pilot study

 

– 13.09.2024: Our recent publication on "Dry Eye Disease and Eye Make-up Products" (Yazdani et al., 2021) has been used by a cosmetics retailer as one of the key references to create a guide for consumers with the condition. This is rarely the case that a market in this field has responded to scientific recommendations. Our goal to help raise public awareness has been met! (Link)

 

– 10.09.2024: The group welcomes "Andrei-Iulian Chitic". He will take his 1.5-month internship with us. Andrei completed his Msc studies at the University of Oslo (UiO) in "Statistics and Psychometrics" (Link). 

 

– 26.08.2024: Some group members attended "The Forth Nordic Metabolomics Conference" in Turku, Finland. A poster was presented by our PhD student:

• Guttorm et al., Impact of Pre-Analytical Factors on the Stability of the Global Metabolome- and Lipidome in Clinical Samples (Download)
  

  

– 12.08.2024: The group welcomes "Ida Havikbotn", an MSc student from University of Oslo (UiO). She will be with us for two years.

 

– 15.07.2024: The group congratulates Cathrin Salvador on the award of the Master's Degree in "Neurometabolism and Cell Biology for Clinicians" from the University of Barcelona and Sant Joan de Déu Barcelona Hospital, Spain. The title of her thesis is 'Neurometabolism and Cell Biology for Clinicians'. 

 

– 03.07.2024: We currently have openings for two Spesialingeniør positions (Deadline: 30.07.2024). The selected candidates will serve for a year until our staff members return from maternity leave.

 

– 24.06.2024: The group welcomes Sára Filipová, an MSc student from the Palacky University in Czechia. She will take her 3-month internship with us.

 

– 18.06.2024:The representatives/experts of a company visited us for consultation and to introduce the latest developments in mass spectrometry for metabolomics and lipidomics. 

 

– 17.06.2024: A poster was presented by Sander Guttorm, our PhD student, at "The 20th Annual Conference of the Metabolomics Society – Metabolomics 2024" in Osaka, Japan. 

• Guttorm et al., Optimization and Evaluation of Global LCMS Lipidomics for use in Clinical Diagnostics (Download)

 

– 03.06.2024: Congratulations to our PhD student, Hanne Skogvold, on her successful thesis defense (Link). 

• Trial lecture: An introduction to inborn errors of metabolism including methodologies for diagnosis in Norway 
• Thesis: Global metabolomics as a tool in clinical research and diagnostics

 

– 27.05.2024: We welcome "Ida Havikbotn", our new team member (Ingeniør). She will be with us for the next 3 months.

 

– 23.05.2024:The group attended the "2nd Norwegian Symposium on Proteomics and Biological Mass Spectrometry" at Holmen Fjordhotell in Oslo, where our "group leader" gave a talk (Link).

• Katja Elgstøen, Global metabolomics in a clinical setting

 

– 21.05.2024: Congratulations to our BSc student "Ida Havikbotn" on her successful thesis defence. 

 

– 03.05.2024: We hosted three other Omics groups, Proteomics Core Facilities (Tuula Anneli Nyman & Bernd Thiede) and Core Facility for Targeted Metabolomics (Nasser Ezzatkhah Bastani). After a short lab tour and tasty lunch together, we had a constructive discussion session.

 

– 23.04.2024: Sonia Distante was appointed as a joint scientific advisory committee member for "Haemochromatosis International and the European Federation of Associations of Patients with Haemochromatosis" at EIC 2024 in Toulouse, France. She has held the position since 2015. 

 

– 03.04.2024: A method paper resolving technical issues with -omics analyses of tear samples collected on Schirmer strips has been published by us (Gundersen et al 2024).

 

– 19.03.2024: A poster was presented by "Ida Havikbotn", our visiting student from NTNU, at the conference in Trondheim for all NTNU bachelor students studying chemical engineering and material science.

• Ida Havikbotn, Implementation of Isotope-labeled Internal Standards in LC-MS based Global Metabolomics (Download)

 

– 14.02.2024: The group has attended in the NOR-MPS Symposium in Oslo and our "group leader" has given a talk (Link).

• Katja Elgstøen, Global metabolomics aims at capturing as many metabolite signatures of a sample as possible

 

– 01.02.2024: Our former Visiting Scholar,"Tara Rolic" from the Osijek University Hospital Centre (Croatia), has published her 3-month internship experience with us in the January-February issue of EFLM Newsletter (Link).

 

– 24.01.2024: The webpage of our "Core Facility" for Global Metabolomics & Lipidomics is now available on the server of University of Oslo (Link).

 

– 22.01.2024: The group has given two talks in the chromatography symposium, Sandefjord, Norway (Link).

• Katja Elgstøen, Implementation of global metabolomics and lipidomics as diagnostic tools in the clinic
• Hanne Skogvold, Investigating the effects of high-intensity training (HIT) using global LC-MS metabolomics and lipidomics

 

– 15.01.2024: First-ever Review paper on underlying mechanisms of Kearns-Sayre syndrome has been published by us (Yazdani 2024).

 

– 08.01.2024: The group welcomes "Ida Havikbotn", a BSc student from Norwegian University of Science and Technology (NTNU). She will be with us for 5 months.

 

– 08.01.2024: The group welcomes "Nathalie Elisebeth", an MSc student from University of Oslo (UiO). She will be with us for a year.

 

– 15.11.2023: Katja Elgstøen and Nils Bolstad were the heads of organizing committee for this year's "MBK Research Seminar" at Voksenåsen Hotel, Oslo.

 

– 01.11.2023: We welcome "Sander Johannes Thorbjørnsen Guttorm", our new PhD student.

 

– 19.10.2023: The group presented three posters at "The 3rd Nordic Metabolomics Conference", Trondheim, Norway. Among them, "Sander Guttorm" was invited to the "Speed-presentations" session.

• Elgstøen et al., Global metabolomics and lipidomics in a university hospital setting (Download)
• Skogvold et al., Global metabolomics reveals severe 3-nitropropionic acid intoxication in a Norwegian patient (Download)
• Guttorm et al., Global LC-MS multi-omics for investigating the effects of High Intensity Training (Download)

 

– 10.10.2023: A new page named "Extracurricular Activities" has been added to our group's website.

 

– 02.10.2023: A presentation on "Clinical significance of hepcidin, iron metabolism and trace elements in the diagnosis of colorectal cancer" has been given to us by Tara Rolic.

 

– 14.09.2023: We welcome "Tara Rolic", a PhD student at the Osijek University Hospital Centre in Croatia. She will take her 3-month internship through EFLMLabX with us.

 

– 25.09.2023: Congratulations to our MSc student "Sander Johannes Thorbjørnsen Guttorm" on his successful thesis defence.

 

– 27.08.2023: A poster entitled "Bloodlettings in Hemochromatosis Result in Increased Blood Lead (Pb) Concentrations" was presented by Dr. Sonia Distante at the 9th Congress of the BioIron in Darwin, Australia.

• Distante et al., Bloodlettings in Hemochromatosis Result in Increased Blood Lead (Pb) Concentrations (Download)

 

– 17.08.2023 We present Metabolomics at "Arendalsuka" for the medical and political leaders of Norway.

 

– 21.07.2023: The effects of preanalytical factors on metabolomics of rare disorders has been published by us (Skogvold et al 2023). 

 

– 17.07.2023: We are appointed as Core Facility for "Global metabolomics and Lipidomics" at the University of Oslo.

 

– 20.06.2023: We currently have an opening for a PhD position in collaboration with the Oslo Metropolitan University (Deadline: 31.08.2022).

 

– 03.06.2023: A comperhensive methodological review on "Dried blood spot analysis" has been written by us (Skogvold et al., 2023).

 

– 01.06.2023: Metabolomikk – kan man se hele mennesket i en dråpe blod? (Link)

 

– 03.05.2023: A hypothesis article proposing a new function for tear film lipid layer has been published in Eye (Nature Publishing Group) by us (Yazdani 2023).

 

– 30.03.2023: An original paper published by our group (Skogvold et al., 2021) has been listed under the Most Read Articles (All Time) of the Journal of Applied Toxicology.

 

– 16.03.2023: Analysene med forsinket svarrapportering går nå som normalt igjen (Link).

 

– 13.03.2023: A poster presented by our bachelor students, Maria Nguyen & Nurtene Dernjani, received an award.

• Nguyen & Dernjani, Global metabolomics as a tool for biomarker detection (Download)

 

– 10.03.2023: EKSPERTSYKEHUSET: Metabolomikk - kraftfullt verktøy for persontilpasset medisin (Link).

 

– 07.03.2023: An internal seminar to elaborate a little on what is special about MET.

 

– 06.03.2023: We welcome Barbora Piskláková, a PhD student from the Clinical Mass Spectrometry Group at the Palacky University in Czechia. She will take her 3-month internship with us.

 

– 03.03.2023: Forsinket svarrapportering fra Seksjon for medfødte metabolske sykdommer (Link). 

 

– 13.02.2023: A nationwide retrospective observational study on "pyridoxine dependent epilepsy" has been published by Erle Kristensen and collaborators (Jamali et al., 2023).

– 24.01.2023: Utvidet diagnose av kolesterolsyntesedefekter (Link). 

 

– 10.01.2023: The group welcomes "Nurtene Dernjani" and "Maria Nguyen", BSc students from OsloMet. They will be with us for 5 months.

 

– 09.01.2023: We welcome "Sander Johannes Thorbjørnsen Guttorm", our new team member (Spesialingeniør). He will be with us for the next year..

 

– 05.01.2023: Nytt analysetilbud i Norge: Nevrotransmittere i spinalvæske (Link).

 

– 09.01.2023: An original article written by Erle Kristensen and collaborators on "Atorvastatin Metabolite Pattern in Skeletal Muscle and Blood" (Lauritzen et al., 2023) has been listed under the "Selected Publications" of the Division of Laboratory Medicine.

 

– 02.01.2023: Our latest orginal article on biomarker discovery of pyridoxine-dependent epilepsy (Böhm et al., 2022) has been listed under the "Selected Publications" of the Division of Laboratory Medicine.

 

– 20.12.2022: A new page named "Learning Materials" has been added to our group's website.

 

– 16.12.2022:The discovery of two novel biomarkers for pyridoxine-dependent epilepsy has been published by us (Böhm et al., 2022).

 

– 15.11.2022: A presentation on "Global Metabolomics Identified new diagnostic markers in PDE-ALDH7A1" has been given by Hans-Otto Böhm, MBK Research Seminar 2022, Voksenåsen, Oslo.

 

– 15.11.2022: Some of group members have participated in "The MBK Annual Research Seminar", Voksenåsen Hotel, Oslo.

 

– 05.11.2022: We currently have an opening for a Spesialingeniør position (Deadline: 24.11.2022). The selected candidate will serve for a year until our staff member returns from maternity leave.

 

– 01.11.2022: A few colleagues from Karolinska Institute in Sweden have visited us.

 

– 03.10.2022: A team has been assembeld for the PhD project of "Morten Pensgård Gundersen". 

 

– 09.09.2022: A review paper published by our group (Yazdani et al., 2021) has been listed under the Most Read Articles (All Time) of Current Eye Research.

– 05.09.2022: A presentation on "Metabolomics study on human 3-nitropropionic acid intoxication" has been given by Hanne Bendiksen Skogvold, The 25th Norwegian Symposium in Chromatography.

 

– 04.09.2022: Best poster prize has been awarded to "Sander Guttorm", The 25th Norwegian Symposium in Chromatography, Sandefjord, Norway (Link). 

 

– 01.09.2022: Some of group members have participated in "The SSIEM Annual Symposium", Freiburg, Germany.

 

– 06.07.2022: A presentation on "Long-term storage has minor effects on biobanked neonatal dried blood spot metabolome" has been given by Katja Elgstøen, DBS Workshop, the UK.

 

– 13.05.2022: Congratulations to our MSc student "Tharsana Sellathurai" on her successful thesis defence.

 

– 01.04.2022: A review paper published by Mazyar Yazdani and colleagues (Tashbayev et al., 2020) has been listed under the Most Downloaded Articles (All Time) of The Ocular Surface (Q1 journal).

 

– 07.03.2022: After COVID19 pandemic, we have re-started our "Metabolomics Club" once every two weeks. In addition to our members, we are honoured hosting Steven Ray Haakon Wilson, Frode Rise and their group members.

 

– 04.03.2022: A thought-provoking review paper, as a wake-up call, for evaluating the nature of oxygen levels in "retinal pigment epithelium" in vitro and the potential impact on cell pathophysiology has been written by us (Yazdani, 2022).

 

– 01.01.2022: We welcome "Hans-Otto Böhm", our new team member (Spesialingeniør). He will be with us for the next year.

 

– 15.10.2021: We currently have an opening for a Spesialingeniør position (Deadline: 01.11.2021). The selected candiate will serve for a year until our staff member returns from maternity leave.

 

– 02.10.2021: A novel metabolomics study of human 3-NPA intoxication, reporting the first case in Norway and the second in Scandinavia, has been published by us (Skogvold et al., 2021).

 

– 10.08.2021: EpilepsiNett has highlighted our lately published PDE review paper (Yazdani and Elgstøen, 2021) on its facebook account (Click here).

 

– 02.08.2021: A pioneer Review article on "Eye Make-up Products and Dry Eye Disease" has been written by us (Yazdani et al., 2021).

 

– 23.07.2021: A new Method Paper, adding valuable information to the field of Clinical Metabolomics, has been published by us (Skogvold et al., 2021).

 

– 17.07.2021: For the first time, "the role of oxidative stress in pyridoxine-dependent epilepsy" has been written by us (Yazdani and Elgstøen, 2021).

 

– 17.06.2021: Congratulations to our MSc student "Marielle Storbråten" on her successful thesis defence.

 

– 25.05.2021: Metabolomics day of our group! A forum to share ideas, discuss detailed issues, review ongoing projects, etc.

 

– 21.04.2021: Group's blog is now available: Metabolomikk - et detaljert øyeblikksbilde av pasienten.

 

– 26.03.2021: VG Newspaper has published a report on Eyelash Growth Serums written by Mazyar Yazdani and Tor Paaske Utheim.

 

– 12.03.2021: A joint PhD Funding Application written by Mazyar Yazdani and a group at Oslo Metropolitan University has been granted.

 

– 01.01.2021: We welcome Mazyar Yazdani,our new team member (Senior Scientist).

 

– 10.12.2020: Congratulations to our 2020 MSc graduates: Hege Sofie Haugan, Katrine Pettersen and Monica Akashnor Kaur.

 

– 15.11.2020: We currently have an opening for a Senior Scientist position (Deadline: 01.11.2020).

 

– 19.11.2020: Metabolomikk; Kunsten å se hele biokjemien (Link).

 

– 22.10.2020: Å lede er å forstå (Link).

 

– 30.09.2019: We are grateful to Dr. Kjell Gunnar Gundersen, the founder of IFOCOUS EyeClinic, for donating NOK 4 million and Professor Tor Paaske Utheim for donating NOK 1.3 million to purchase the top-of-the-line Orbitrap Fusion™ Tribrid™ Mass Spectrometer.

 

– 05.08.2019: Our latest review article on Tear Metabolomics (Yazdani et al., 2019) has been listed under the "Selected Publications" of the Division of Laboratory Medicine.

 

– 30.07.2019: First-ever Review Paper on "Tear Metabolomics in Dry Eye Disease" has been published by us (Yazdani et al., 2019).

---

WELCOME    MEMBERS    COLLABORATORS    RESEARCH    PUBLICATIONS    LEARNING MATERIALS    GALLERY    NEWS