Barbora Piskláková

  • Spesialingeniør; PhD
  • +47 230 70 911

Education

  • 2020-2024: PhD in Medical chemistry and Clinical Biochemistry, Palacky University Olomouc, Czechia
  • 2018-2020: MSc in Biochemistry, Palacky University Olomouc, Czechia
  • 2015-2018: BSc in Biochemistry, Palacky University Olomouc, Czechia

Affiliation

Research Summary

Dr. Piskláková's work focuses on LC-MS method development and metabolomic analysis. She is interested in applying global metabolomics for patient diagnosis and integrating metabolomics into clinical practice.

Highlights:

  • 2023: 3rd place in the competition for the best work of young authors in the field of spectroscopy in 2023: Rapid and efficient LC-MS/MS diagnosis of inherited metabolic disorders: a semi-automated workflow for the diagnosis of organic acids, acylglycines and acylcarnitines in urine. Jak Marek Marci Spectroscopic Society, Faculty of Chemical Technology, University of Pardubice, Pardubice, Czechia
  • 2023: Travel scholarship from the EJPRD programme of the MetbERN network: 3-month internship at Oslo University Hospital, Project Study of the pathobiochemistry of selected inherited metabolic disorders by metabolomics
  • 2022: Dean’s Award for significant publication activity in 2021: Evaluation of the Determination of Dabigatran, Rivaroxaban, and Apixaban in Lupus Anticoagulant-Positive Patients, Diagnostics
  • Lecturer of the seminar and laboratory practical exercises of the course Medicinal Chemistry (for first-year students of general medicine) – 2 hours every second week (winter semester 2021)
  • Supervisor of 4 students for Bachelors and Masters theses

Work Experience

  • 2024 October-Present: Spesialingeniør at the Department of Medical Biochemistry, Oslo University Hospital, Norway
  • 2020 September-2024 September: Assistant and junior researcher at the Faculty of Medicine and Dentistry, Palacký University Olomouc, Czechia
  • 2023 January-2024 September: Researcher at the Laboratory of Inherited Metabolic disorders, University Hospital Olomouc, Czechia
  • 2023 March-June: Guest researcher (Internship) at Katja Elgstøen’s lab, Department of Medical Biochemsitry, Oslo University Hospital, Norway

Links

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Publications 2025

Dobešová D, Prídavok M, Brumarová R, Kvasnička A, Piskláková B, Ivanovová E, Brennerová K, Šaligová J, Potočňáková Ľ, Drobňaková S, Potočňáková J, Friedecký D (2025)
Comprehensive metabolomic/lipidomic characterization of patients with mitochondrial ATP synthase, short-chain acyl-CoA dehydrogenase and combined variant deficiencies
Heliyon, 11 (4), e42797
DOI 10.1016/j.heliyon.2025.e42797, PubMed 41477503

Kvasnička A, Friedecký D, Piskláková B, Rozhon J, Pavelka K, Stibůrková B (2025)
Ceramide-based risk score: A novel laboratory tool for cardiovascular risk stratification in hyperuricemia and gout
Vascul Pharmacol, 159, 107495
DOI 10.1016/j.vph.2025.107495, PubMed 40239856

Ligasová A, Frydrych I, Piskláková B, Friedecký D, Koberna K (2025)
The kinetics of uracil-N-glycosylase distribution inside replication foci
Sci Rep, 15 (1), 3026
DOI 10.1038/s41598-024-84408-x, PubMed 39849039

Publications 2024

Ivanovová E, Piskláková B, Dobešová D, Janečková H, Foltenová H, Kvasnička A, Prídavok M, Bouchalová K, de Sousa J, Friedecký D (2024)
Wide metabolite coverage LC-MS/MS assay for the diagnosis of inherited metabolic disorders in urine
Talanta, 271, 125699
DOI 10.1016/j.talanta.2024.125699, PubMed 38262132

Publications 2023

Kvasnička A, Najdekr L, Dobešová D, Piskláková B, Ivanovová E, Friedecký D (2023)
Clinical lipidomics in the era of the big data
Clin Chem Lab Med, 61 (4), 587-598
DOI 10.1515/cclm-2022-1105, PubMed 36592414

Ligasová A, Piskláková B, Friedecký D, Koberna K (2023)
A new technique for the analysis of metabolic pathways of cytidine analogues and cytidine deaminase activities in cells
Sci Rep, 13 (1), 20530
DOI 10.1038/s41598-023-47792-4, PubMed 37993628

Piskláková B, Friedecká J, Ivanovová E, Hlídková E, Bekárek V, Prídavok M, Kvasnička A, Adam T, Friedecký D (2023)
Rapid and efficient LC-MS/MS diagnosis of inherited metabolic disorders: a semi-automated workflow for analysis of organic acids, acylglycines, and acylcarnitines in urine
Clin Chem Lab Med, 61 (11), 2017-2027
DOI 10.1515/cclm-2023-0084, PubMed 37207286

Publications 2022

Bradáčová P, Slavík L, Skoumalová A, Úlehlová J, Kriegová E, Manukyan G, Friedecký D, Piskláková B, Ullrychová J, Procházková J, Hluší A (2022)
Determination of Thrombogenicity Levels of Various Antiphospholipid Antibodies by a Modified Thrombin Generation Assay in Patients with Suspected Antiphospholipid Syndrome
Int J Mol Sci, 23 (16)
DOI 10.3390/ijms23168973, PubMed 36012233

Publications 2021

Úlehlová J, Piskláková B, Ivanovová E, Procházková J, Bradáčová P, Kvasnička A, Friedecký D, Slavík L (2021)
Evaluation of the Determination of Dabigatran, Rivaroxaban, and Apixaban in Lupus Anticoagulant-Positive Patients
Diagnostics (Basel), 11 (11)
DOI 10.3390/diagnostics11112027, PubMed 34829374

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