Antiviral drugs could preserve insulin in children newly diagnosed with type 1 diabetes
A research group at the Department of Paediatric Medicine at OUH and the UiO has demonstrated that they are able to reduce some of the loss of insulin production in the body, by administering antivirus medication to children and adolescents with newly diagnosed type 1 diabetes.
The study is published in the prestigious journal Nature Medicine. First authors are Lars Krogvold and PhD student Ida Mynarek.
"The finding largely shows that a virus trigger type 1 diabetes in children," says Knut Dahl-Jørgensen, consultant at OUH and Senior Professor at UiO, who led the study.
Links:
Complete and comprehensive original news article from the University of Oslo home page:
Antiviral drugs could preserve insulin in children newly diagnosed with type 1 diabetes (med.uio.no), by Julie Nybakk Kvaal
The Nature Medicine article:
Pleconaril and ribavirin in new-onset type 1 diabetes: a phase 2 randomized trial.
Krogvold L, Mynarek IM, Ponzi E, Mørk FB, Hessel TW, Roald T, Lindblom N, Westman J, Barker P, Hyöty H, Ludvigsson J, Hanssen KF, Johannesen J, Dahl-Jørgensen K.
Nat Med. 2023 Oct 4. doi: 10.1038/s41591-023-02576-1. Online ahead of print.
PMID: 37789144
Childhood Diabetes research group home page at Oslo Diabetes Research Centre