The Malmberg lab partner in major cancer immunotherapy project
The Malmberg Lab is one of four partners in project that recently was awarded 31 MSEK to study and develop new technologies for cancer immunotherapy. The constellation is led by Professor Bjorn Onfelt at the Royal Institute of Technology in Sweden.
The team focus on T and NK cells and their interactions with tumor cells in both 2D and 3D models.
“One of the most exciting things with this collaboration is the interdisciplinary collaboration between biologists, clinical scientists and phycisists”, says Kalle Mamberg, who holds a Visiting Professor position at the Karolinska Institute.
The key challenge is to identify the right cells for the job of eliminating tumor cells. Onfelt Lab has developed a microchip screening platform with 30.000 wells measuring 22x22micrometer. The confined area and multiple wells allows visualization and quantification of multiple, serial interactions using advanced confocal microscopy. It holds potential to identify subpopulations of cells with increased killing capacity.
Published in Level 2 journals, first or last author from Oslo University Hospital.
Spalding T, LaPrade RF, Murray IR, Krych AJ, Engebretsen L(2024) Favorable Patient-Reported, Clinical, and Functional Outcomes 2 Years After ACL Repair and InternalBrace Augmentation Compared With ACL Reconstruction and Healthy Controls: Letter to the Editor Am J Sports Med, 52(8), NP15 DOI 10.1177/03635465241247750, PubMed 38946455
Bukten A, Stavseth MR(2024) Estimated effects of opioid agonist treatment in prison on all-cause mortality and overdose mortality in people released from prison in Norway: a prospective analysis of data from the Norwegian Prison Release Study (nPRIS) Lancet Public Health, 9(7), e421-e431 DOI 10.1016/S2468-2667(24)00098-7, PubMed 38942554
Ness HT, Folvik L, Sneve MH, Grydeland H, Vidal-PiƱeiro D, Raud L, Geier OM, Walhovd KB, Fjell AM(2024) Recalled through this day but forgotten next week?-retrieval activity predicts durability of partly consolidated memories Cereb Cortex, 34(6) DOI 10.1093/cercor/bhae233, PubMed 38937077