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17.09.2019Play equipment that gets kids moving

Parents will be pleased to know that more is not always better when it comes to play equipment for their children.

17.09.2019Stroke patients relearning how to walk with peculiar shoe

Clinical trials have been completed on a therapeutic shoe engineered to improve stroke recovery. They've proven successful, allowing for the patented product to hit the market by the end of the year.

17.09.2019Female athletes seek specialty care for concussion later than males

Female athletes seek specialty medical treatment later than male athletes for sports-related concussions (SRC), and this delay may cause them to experience more symptoms and longer recoveries.

17.09.2019Synthetic cells capture and reveal hidden messages of the immune system

New research is highly relevant to how antibodies are made in response to infections, vaccines and in autoimmunity due to the its analysis of a signal that is associated with hyper IgM syndrome, a genetic deficiency of CD40 ligand (CD40L) that results in profound immunodeficiency.

17.09.2019Scientists prove low cost arthritis drug can effectively treat blood cancer sufferers

A simple arthritis drug could be an effective, low cost solution to treat patients with blood cancers such as polycythemia vera (PV) and essential thrombocythemia (ET), a breakthrough study has shown.

17.09.2019Virtual reality training could improve employee safety

A new study suggests employee safety could be improved through use of virtual reality (VR) in Health and Safety training, such as fire evacuation drills. Researchers developed an immersive VR system to stimulate participants' perception of temperature, and senses of smell, sight and hearing to explore how they behaved during two health and safety training scenarios.

17.09.2019Short-term study suggests vegan diet can boost gut microbes related to body weight, body composition and blood sugar control

New research suggests that a 16-week vegan diet can boost the gut microbes that are related to improvements in body weight, body composition and blood sugar control.

17.09.2019Light drinking may be beneficial in type 2 diabetes: Further research needed

An meta-analysis of studies shows that recommendations to moderate alcohol consumption for people with type 2 diabetes may need to be reviewed, since low-to-moderate consumption could have a positive effect on blood glucose and fat metabolism.

17.09.2019Overgrowth of baby in womb may begin weeks before women are tested for maternal diabetes

The excessive growth of a baby in the womb, a common complication of gestational diabetes, begins weeks before women are tested for the disease, according to new research.

17.09.2019Later puberty and later menopause associated with lower risk of type 2 diabetes in women

New research shows that use of the contraceptive pill and longer menstrual cycles are associated with a higher risk of developing type 2 diabetes (T2D), while later puberty and later menopause are associated with lower risk.

17.09.2019Shorter people are at higher risk of type 2 diabetes, study shows

Short stature is associated with a higher risk of type 2 diabetes, according to a new study. Tall stature is associated with a lower risk, with each 10cm difference in height associated with a 41 percent decreased risk of diabetes in men and a 33 percent decreased risk in women.

16.09.2019More than Lyme: Tick study finds multiple agents of tick-borne diseases

Scientists reported on the prevalence of multiple agents capable of causing human disease that are present in three species of ticks in Long Island.

16.09.2019Human hearts evolved for endurance

Major physical changes occurred in the human heart as people shifted from hunting and foraging to farming and modern life. As a result, human hearts are now less 'ape-like' and better suited to endurance types of activity.

16.09.2019Defective cilia linked to heart valve birth defects

Bicuspid aortic valve (BAV), the most common heart valve birth defect, is associated with genetic variation in human primary cilia during heart valve development, report researchers. Crucial to cilia development is the exocyst, which shuttles cilia cargo to the cell membrane. Disrupting the exocyst impaired ciliogenesis and caused a spectrum of cardiac defects in zebrafish and BAV in mice.

16.09.2019Renegade genes caught red-handed

Potentially dangerous genes embedded within human DNA were once thought to be locked down by helpful DNA structures called heterochromatin. A researcher disputes that belief and hopes to change the paradigm even further.

16.09.2019Big data, bench science suggests drug may slow Parkinson's progression in people

A drug used to treat enlarged prostate may also slow the progression of Parkinson's disease, according to a new study.

16.09.2019Genetically engineered plasmid can be used to fight antimicrobial resistance

Researchers have engineered a plasmid to remove an antibiotic resistance gene from the Enterococcus faecalis bacterium, an accomplishment that could lead to new methods for combating antibiotic resistance.

16.09.2019For kids who face trauma, good neighbors or teachers can save their longterm health

New research shows just how important positive childhood experiences are for long-term health, especially for those who experience significant adversity as a child. Studies over the past 20 years have found a correlation between adverse childhood events (such as death or divorce) and worse health outcomes later in life. A new study discovers that positive childhood experiences, like having good neighbors, or a teacher you trust, have the potential to negate harmful health effects caused by adverse childhood experiences.

16.09.2019Anemia may contribute to the spread of dengue fever

Mosquitoes are more likely to acquire the dengue virus when they feed on blood with low levels of iron, researchers report. Supplementing people's diets with iron in places where both iron deficiency anemia and dengue fever are a problem could potentially limit transmission of the disease, but there are risks.

16.09.2019Social isolation derails brain development in mice

Female mice housed alone during adolescence show atypical development of the prefrontal cortex and resort to habitual behavior in adulthood, according to new research. These findings show how social isolation could lead to an over-reliance on habit-like behaviors that are associated with addiction and obesity.

16.09.2019Climate change expected to accelerate spread of sometimes-fatal fungal infection

Valley fever is endemic to hot and dry regions like the southwestern United States and California's San Joaquin Valley, but a new study predicts climate change will cause the fungal infection's range to more than double in size this century, reaching previously unaffected areas across the western U.S.

16.09.2019Too much of a good thing: Overactive immune cells trigger inflammation

Scientists describe a previously unknown disorder of the immune system: in a distinct subset of immune cells from patients with primary immunodeficiency, cellular respiration is significantly increased. This cellular metabolic overactivity leads to inflammation.

16.09.2019Lack of sleep affects fat metabolism

A restricted-sleep schedule built to resemble an American work week made study participants feel less full after a fatty meal and altered their lipid metabolism. One night of recovery sleep helped, but didn't completely erase the effects of sleep restriction.

16.09.2019Like an instruction manual, the genome groups genes together for convenience

Scientists at the Centre for Genomic Regulation (CRG) in Barcelona shed light on how the genome organizes groups of genes linked to specific processes, like the release of toxins.

16.09.2019Deaths halved among infarct patients attending Heart School

Patients who attend 'Heart School', as almost every patient in Sweden is invited to do after a first heart attack, live longer than non-participating patients.

16.09.2019Starting HIV treatment in ERs may be key to ending HIV spread worldwide

Researchers say they have evidence that hospital emergency departments (EDs) worldwide may be key strategic settings for curbing the spread of HIV infections in hard-to-reach populations if the EDs jump-start treatment and case management as well as diagnosis of the disease.

16.09.2019Measuring ethanol's deadly twin

Researchers have developed an inexpensive, handheld measuring device that can distinguish between methanol and potable alcohol. It offers a simple, quick method of detecting adulterated or contaminated alcoholic beverages and is able to diagnose methanol poisoning in exhaled breath.

16.09.2019Importance of when adolescents sleep to obesity and cardiometabolic health

New study finds adolescent sleep timing preferences and patterns should be considered risk factors for obesity and cardiometabolic health.

16.09.2019Brain activity intensity drives need for sleep

The intensity of brain activity during the day, notwithstanding how long we've been awake, appears to increase our need for sleep, according to a new study in zebrafish.

16.09.2019Vitamin E found to prevent muscle damage after heart attack

Early studies have found Vitamin E could be used to save the muscle from dying during a heart attack.

16.09.2019Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

A study carried out with a new human stem cell-derived model reveals that the most prevalent genetic risk factor of Alzheimer's disease (AD), apolipoprotein E4 (APOE4), impairs the function of human brain immune cells, microglia. These findings pave the way for new, effective treatment approaches for AD.

16.09.2019Sweet success of parasite survival could also be its downfall

Scientists have discovered how a parasite responsible for spreading a serious tropical disease protects itself from starvation once inside its human host. The findings provide a new understanding of the metabolism of the Leishmania parasite and this new knowledge could potentially be used in its eradication.

16.09.2019More than every second female homicide is committed by the partner

Intimate partner homicide - that is women who are killed by their partner - constitutes a significant proportion of the homicide statistics.

16.09.2019Scanning the lens of the eye could predict type 2 diabetes and prediabetes

New research shows that specialist analysis of the lens in the eye can predict patients with type 2 diabetes and impaired glucose tolerance (IGT) (also known as prediabetes, a condition that often leads to full blown of type 2 diabetes).

16.09.2019Transplanted brain stem cells survive without anti-rejection drugs in mice

In experiments in mice, researchers say they have developed a way to successfully transplant certain protective brain cells without the need for lifelong anti-rejection drugs.

16.09.2019Violent video games blamed more often for school shootings by white perpetrators

People are more likely to blame violent video games as a cause of school shootings by white perpetrators than by African-American perpetrators, possibly because of racial stereotypes that associate minorities with violent crime, according to new research.

16.09.2019Subgroup of colorectal cancer patients ID'd: Do poorly, could benefit from immunotherapy

While the medical community agrees immune cells inside a tumor leads to improved health outcome, for a subset of colorectal cancer patients, having too much of a good thing is a strong predictor of disease recurrence and reduced chances of survival. Scientists identify patients who could benefit from immunotherapy. This is the first report of immune infiltrated tumors with poor health outcomes and is counter to the standard belief in the field.

16.09.2019Just bad luck? Cancer patients nominate 'fate' as third most likely cause

What role does fate play when it comes to the 145,000 people diagnosed with cancer each year in Australia and 125,000 people in Vietnam?

16.09.2019Gutsy effort to produce comprehensive study of intestinal gases

Chemical engineers have traced the journey of gases through the gut while further developing a non-invasive, gas-capturing capsule.

16.09.2019Obesity linked to a nearly 6-fold increased risk of developing type 2 diabetes, with genetics and lifestyle also raising risk

Obesity is linked to a nearly 6-fold increased risk of developing type 2 diabetes (T2D), with high genetic risk and unfavorable lifestyle also increasing risk but to a much lesser extent.

16.09.2019Childhood behavior linked to taking paracetamol in pregnancy

A new study adds to evidence that links potential adverse effects of taking paracetamol (also known as acetaminophen) during pregnancy.

16.09.20193 in 5 parents say their teen has been in a car with a distracted teen driver

More than 1/2 of parents say their child has probably been in an unsafe situation as a passenger with a teen driver.

16.09.2019Immune response depends on mathematics of narrow escapes

The way immune cells pick friends from foes can be described by a classic maths puzzle known as the 'narrow escape problem'.

16.09.2019Heart-healthy forager-farmers in lowland Bolivia are changing diets and gaining weight

A group of forager-farmers in Bolivia's tropical forests -- known for having remarkable cardiovascular health and low blood pressure -- experienced changes in body mass and diet over a nine-year period, with increased use of cooking oil being the most notable dietary change.

16.09.2019Physicians report high refusal rates for the HPV vaccine and need for improvement

Despite its proven success at preventing cancer, many adolescents are still not getting the HPV vaccine. A new study from shows that physicians' delivery and communication practices must improve to boost vaccination completion rates.

16.09.2019Off-label medication orders on the rise for children

US physicians are increasingly ordering medications for children for conditions that are not approved by the Food and Drug Administration, according to a new study. The findings highlight the need for more education, research and policies addressing effective, safe pediatric drug prescribing.

14.09.2019New way to target cancer's diversity and evolution

Scientists have revealed close-up details of a vital molecule involved in the mix and match of genetic information within cells -- opening up the potential to target proteins of this family to combat cancer's diversity and evolution.

14.09.2019Predicting risk of heart failure for diabetes patients with help from machine learning

A new study unveils a new, machine-learning derived model that can predict, with a high degree of accuracy, future heart failure among patients with diabetes.

13.09.2019Gene editing tool gets sharpened by WFIRM team

Scientists have fine-tuned their delivery system to deliver a DNA editing tool to alter DNA sequences and modify gene function. The improved 'hit and run' system works faster and is more efficient.

13.09.2019How IL-6 allows the immune response to develop for a key cell, the T follicular helper

A preclinical study shows how the interplay of two interleukin signaling proteins, IL-6 and IL-2, affects the development of T follicular helper cells and germinal centers. This interplay may either maintain or disrupt the balancing act of the immune system between attacking infections and benign surveillance of the body's own cells. Thus, the research may help guide future disease treatment for autoimmune diseases like lupus.

13.09.2019Therapeutic strategies for pregnant women with lupus

A highly gender-biased disease, lupus afflicts females some nine times more than males. Because of the disease's unpredictable turns and debilitating flares -- the risks of which are elevated in postpartum women -- females with the disease are often advised to avoid pregnancy altogether.

13.09.2019Focus points to reduce opioid overdose deaths identified

A new study identifies specific locations where medication and harm reduction services for people with opioid use disorder should be available in order to have the greatest impact on reducing opioid overdose deaths. The data show that more than half of those who died of an opioid overdose in Massachusetts encountered the health care, public health and/or criminal justice systems within the 12 months prior to their fatal overdose.

13.09.2019Few people with peanut allergy tolerate peanut after stopping oral immunotherapy

Studies have shown that peanut oral immunotherapy (OIT) -- ingesting small, controlled amounts of peanut protein -- can desensitize adults and children and prevent allergic reactions, but the optimal duration and dose is unknown. In a study that followed participants after successful OIT, discontinuing OIT or continuing OIT at a reduced dose led to a decline in its protective effects. The study also found that blood tests administered before OIT could predict the success of therapy.

13.09.2019How new loops in DNA packaging help us make diverse antibodies

It's long been known that our immune cells mix and match bits of genetic code to make new kinds of antibodies to fight newly encountered threats. But how these different gene segments come together has been a mystery. A study provides the answer, showing how the classic process of V(D)J recombination makes use of chromatin looping to gather the segments to be spliced.

13.09.2019Speeding up the drug discovery process to help patients

An international research team is perfecting a method to predict the potential clinical implications of new drugs before clinical trials even start.

13.09.2019'Communities that Care' prevention system helps to protect youth

Students in Pennsylvania school districts that participated in Communities that Care (CTC) coalitions were significantly less likely to use alcohol or marijuana, or to engage in delinquent behavior than those in non-CTC districts, according to a recent study.

13.09.2019Slower growth in working memory linked to teen driving crashes

Research into why adolescent drivers are involved in motor vehicle crashes, the leading cause of injury and death among 16- to 19-year-olds in the United States, has often focused on driving experience and skills. But a new study suggests that development of the adolescent brain -- in particular, working memory -- may play a critical role in whether a teenager is more likely to crash.

13.09.2019Addressing serious illness with a serious question to clinicians

A question: 'Would you be surprised if this patient died in the next month?' -- posed to elicit a clinician's overall impression of a patient -- produced a strong correlation. If a clinician answered that they would not be surprised, the patient was twice as likely to die in the next month.

13.09.2019High social support associated with less violence among male teens in urban neighborhoods

Researchers find that the presence of adult social support is linked to less violence among at-risk teen boys.

13.09.2019Tiny bubbles in our body could fight cancer better than chemo

Healthy cells in our body release nano-sized bubbles that transfer genetic material such as DNA and RNA to other cells. It's your DNA that stores the important information necessary for RNA to produce proteins and make sure they act accordingly. These bubbly extracellular vesicles could become mini treatment transporters, carrying a combination of therapeutic drugs and genes that target cancer cells and kill them, according to new research from Michigan State University and Stanford University.

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