New research from NORMENT finds that people with schizophrenia have a genetic propensity to smoking and a reduced genetic risk of obesity. The study highlight the importance of including lifestyle interventions in treatment for schizophrenia.
"The genetic overlap between schizophrenia and smoking may indicate that people with schizophrenia are more affected by the addictive properties of nicotine than others", first author Linn Rødevand says. She is a postdoctoral fellow at NORMENT - the Norwegian Center for Research on Mental Disorders.
The study is published in the American Journal of Psychiatry.
Complete and comprehensive original news article from the University of Oslo home page:
New research identifies genetic links between Schizophrenia and Cardiovascular Disease risk factors (med.uio.no), by Julie Nybakk Kvaal
The American Journal of Psychiatry article:
Characterizing the Shared Genetic Underpinnings of Schizophrenia and Cardiovascular Disease Risk Factors.
Rødevand L, Rahman Z, Hindley GFL, Smeland OB, Frei O, Tekin TF, Kutrolli G, Bahrami S, Hoseth EZ, Shadrin A, Lin A, Djurovic S, Dale AM, Steen NE, Andreassen OA.
Am J Psychiatry. 2023 Sep 27:appiajp20220660. doi: 10.1176/appi.ajp.20220660. Online ahead of print.
NORMENT – Norwegian Centre for Mental Disorders Research (ous-research.no)