Publication in Lancet: Pain relief without the use of a needle

"We have finally found a good alternative for pain relief right at the start, when it can be difficult to give painkillers through a needle", say the researchers behind the PreMeFen study, which was recently published in the prestigious journal The Lancet.
The study is led by Fridtjof Heyerdahl, a senior researcher at SNLA, OUS and UiO, and head of the Air Ambulance Department at OUS. The study's first author is Randi Simensen, a research fellow at SNLA and Innlandet Hospital.
One patient group received the medication methoxyflurane, which was inhaled through a pipe. The other group received a nasal spray with the medication fentanyl. The last group of patients received morphine via a needle in a vein, which is the treatment that has been used for several decades. The PreMeFen study is the first randomized controlled trial in the world to compare these three treatment options. And it is being done in the ambulance service, where the patients are.






