Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2021 from OUS - Section for gastrointestinal oncology

20 publications found

Bahadoer RR, Bastiaannet E, Claassen YHM, van der Mark M, van Eycken E, Verbeeck J, Guren MG, Kørner H, Martling A, Johansson R, van de Velde CJH, Dekker JWT (2021)
One-year excess mortality and treatment in surgically treated patients with colorectal cancer: A EURECCA European comparison
Eur J Surg Oncol, 47 (7), 1651-1660
DOI 10.1016/j.ejso.2021.01.011, PubMed 33518367

Choudhury A, Theophanous S, Lønne PI, Samuel R, Guren MG, Berbee M, Brown P, Lilley J, van Soest J, Dekker A, Gilbert A, Malinen E, Wee L, Appelt AL (2021)
Predicting outcomes in anal cancer patients using multi-centre data and distributed learning - A proof-of-concept study
Radiother Oncol, 159, 183-189
DOI 10.1016/j.radonc.2021.03.013, PubMed 33753156

Dueland S, Yaqub S, Syversveen T, Carling U, Hagness M, Brudvik KW, Line PD (2021)
Survival Outcomes After Portal Vein Embolization and Liver Resection Compared With Liver Transplant for Patients With Extensive Colorectal Cancer Liver Metastases
JAMA Surg., 156 (6), 550-557
DOI 10.1001/jamasurg.2021.0267

Guren MG, Sebag-Montefiore D, Franco P, Johnsson A, Segelov E, Deutsch E, Rao S, Spindler KG, Arnold D (2021)
Treatment of Squamous Cell Carcinoma of the Anus, Unresolved Areas and Future Perspectives for Research: Perspectives of Research Needs in Anal Cancer
Clin Colorectal Cancer (in press)
DOI 10.1016/j.clcc.2021.09.006, PubMed 34645589

Hamfjord J, Guren TK, Glimelius B, Sorbye H, Pfeiffer P, Dajani O, Lingjaerde OC, Tveit KM, Pallisgaard N, Spindler KG, Kure EH (2021)
Clinicopathological factors associated with tumour-specific mutation detection in plasma of patients with RAS-mutated or BRAF-mutated metastatic colorectal cancer
Int J Cancer, 149 (6), 1385-1397
DOI 10.1002/ijc.33672, PubMed 33961700

Hjermstad MJ, Hamfjord J, Aass N, Dajani O, Lundeby T, Wester T, Kaasa S (2021)
Using Process Indicators to Monitor Documentation of Patient-Centred Variables in an Integrated Oncology and Palliative Care Pathway-Results from a Cluster Randomized Trial
Cancers (Basel), 13 (9)
DOI 10.3390/cancers13092194, PubMed 34063594

Kryeziu K, Moosavi SH, Bergsland CH, Guren MG, Eide PW, Totland MZ, Lassen K, Abildgaard A, Nesbakken A, Sveen A, Lothe RA (2021)
Increased sensitivity to SMAC mimetic LCL161 identified by longitudinal ex vivo pharmacogenomics of recurrent, KRAS mutated rectal cancer liver metastases
J Transl Med, 19 (1), 384
DOI 10.1186/s12967-021-03062-3, PubMed 34496878

Lanari J, Hagness M, Sartori A, Rosso E, Gringeri E, Dueland S, Cillo U, Line PD (2021)
Liver transplantation versus liver resection for colorectal liver metastasis: a survival benefit analysis in patients stratified according to tumor burden score
Transpl Int, 34 (9), 1722-1732
DOI 10.1111/tri.13981, PubMed 34448271

Mariathasan AB, Boye K, Dueland S, Flatmark K, Larsen SG (2021)
Metastases in locally advanced rectal cancer undergoing curatively intended treatment
Eur J Surg Oncol, 47 (9), 2377-2383
DOI 10.1016/j.ejso.2021.04.023, PubMed 34049768

Meltzer S, Torgunrud A, Abrahamsson H, Solbakken AM, Flatmark K, Dueland S, Bakke KM, Bousquet PA, Negård A, Johansen C, Lyckander LG, Larsen FO, Schou JV, Redalen KR, Ree AH (2021)
The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer
Br J Cancer, 125 (2), 240-246
DOI 10.1038/s41416-021-01377-y, PubMed 33837301

Moosavi SH, Eide PW, Eilertsen IA, Brunsell TH, Berg KCG, Røsok BI, Brudvik KW, Bjørnbeth BA, Guren MG, Nesbakken A, Lothe RA, Sveen A (2021)
De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity
Genome Med, 13 (1), 143
DOI 10.1186/s13073-021-00956-1, PubMed 34470666

Nilssen Y, Eriksen MT, Guren MG, Møller B (2021)
Factors associated with emergency-onset diagnosis, time to treatment and type of treatment in colorectal cancer patients in Norway
BMC Cancer, 21 (1), 757
DOI 10.1186/s12885-021-08415-1, PubMed 34187404

Osterman E, Ekström J, Sjöblom T, Kørner H, Myklebust TÅ, Guren MG, Glimelius B (2021)
Accurate population-based model for individual prediction of colon cancer recurrence
Acta Oncol, 60 (10), 1241-1249
DOI 10.1080/0284186X.2021.1953138, PubMed 34279175

Pommergaard HC, Nielsen K, Sorbye H, Federspiel B, Tabaksblat EM, Vestermark LW, Janson ET, Hansen CP, Ladekarl M, Garresori H, Hjortland GO, Sundlov A, Galleberg R, Knigge P, Kjaer A, Langer SW, Knigge U (2021)
Surgery of the primary tumour in 201 patients with high-grade gastroenteropancreatic neuroendocrine and mixed neuroendocrine-non-neuroendocrine neoplasms
J. Neuroendocrinol., 33 (5), e12967
DOI 10.1111/jne.12967

Rao S, Guren MG, Khan K, Brown G, Renehan AG, Steigen SE, Deutsch E, Martinelli E, Arnold D, ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org (2021)
Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Ann Oncol, 32 (9), 1087-1100
DOI 10.1016/j.annonc.2021.06.015, PubMed 34175386

REACCT Collaborative, Zaborowski AM, Abdile A, Adamina M, Aigner F, d'Allens L, Allmer C, Álvarez A, Anula R, Andric M, Atallah S, Bach S, Bala M, Barussaud M, Bausys A, Bebington B, Beggs A, Bellolio F, Bennett MR, Berdinskikh A, Bevan V, Biondo S, Bislenghi G, Bludau M, Boutall A et al. (2021)
Characteristics of Early-Onset vs Late-Onset Colorectal Cancer: A Review
JAMA Surg, 156 (9), 865-874
DOI 10.1001/jamasurg.2021.2380, PubMed 34190968

Slørdahl KS, Klotz D, Olsen JÅ, Skovlund E, Undseth C, Abildgaard HL, Brændengen M, Nesbakken A, Larsen SG, Hanekamp BA, Holmboe L, Tvedt R, Sveen A, Lothe RA, Malinen E, Kaasa S, Guren MG (2021)
Treatment outcomes and prognostic factors after chemoradiotherapy for anal cancer
Acta Oncol, 60 (7), 921-930
DOI 10.1080/0284186X.2021.1918763, PubMed 33966592

Thorgersen EB, Asvall J, Frøysnes IS, Schjalm C, Larsen SG, Dueland S, Andersson Y, Fodstad Ø, Mollnes TE, Flatmark K (2021)
Increased Local Inflammatory Response to MOC31PE Immunotoxin After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
Ann Surg Oncol, 28 (9), 5252-5262
DOI 10.1245/s10434-021-10022-0, PubMed 34019185

Torstveit AH, Løyland B, Grov EK, Guren M, Paul SM, Ritchie C, Vistad I, Miaskowski C, Utne I (2021)
Distinctions Between Self-Report and Performance-Based Measures of Physical Function in Older Patients Prior to Chemotherapy
Cancer Nurs (in press)
DOI 10.1097/NCC.0000000000000964, PubMed 34183518

Torstveit AH, Miaskowski C, Løyland B, Grov EK, Guren MG, Ritchie CS, Paul SM, Kleven AG, Utne I (2021)
Common and distinct characteristics associated with self-reported functional status in older patients with cancer receiving chemotherapy
Eur J Oncol Nurs, 54, 102033 (in press)
DOI 10.1016/j.ejon.2021.102033, PubMed 34537538

 
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