Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2021 from OUS - Department of Forensic Sciences

42 publications found

Andersen JM, Bogen IL, Karinen R, Brochmann GW, Mørland J, Vindenes V, Boix F (2021)
Does the preparation for intravenous administration affect the composition of heroin injections? A controlled laboratory study
Addiction, 116 (11), 3104-3112
DOI 10.1111/add.15492, PubMed 33739552

Bech AB, Clausen T, Waal H, Delaveris GJM, Skeie I (2021)
Organ pathologies detected post-mortem in patients receiving opioid agonist treatment for opioid use disorder: a nationwide 2-year cross-sectional study
Addiction (in press)
DOI 10.1111/add.15705, PubMed 34648218

Bergh MS, Bogen IL, Garibay N, Baumann MH (2021)
Pharmacokinetics and pharmacodynamics of cyclopropylfentanyl in male rats
Psychopharmacology (Berl)
DOI 10.1007/s00213-021-05981-x, PubMed 34613431

Bergh MSS, Bogen IL, Nerem E, Wohlfarth A, Wilson SR, Oiestad AML (2021)
Discovering the major metabolites of the three novel fentanyl analogues 3-methylcrotonylfentanyl, furanylbenzylfentanyl, and 4-fluorocyclopropylbenzylfentanyl for forensic case work
Forensic Toxicol., 39 (1), 167-178
DOI 10.1007/s11419-020-00560-9

Breen JM, Næss PA, Gaarder C, Stray-Pedersen A (2021)
Autopsy findings in drivers and passengers from fatal motor vehicle collisions: limited differences in injury patterns and toxicological test results
Forensic Sci Med Pathol, 17 (2), 235-246
DOI 10.1007/s12024-021-00359-z, PubMed 33609266

Bye EK, Bogstrand ST, Rossow I (2021)
The importance of alcohol in elderly's hospital admissions for fall injuries: a population case-control study
Nord. Stud. Alcohol Drugs, 14550725211015836
DOI 10.1177/14550725211015836

Chalabianloo F, Fadnes LT, Høiseth G, Ohldieck C, Vold JH, Aas C, Løberg EM, Johansson KA, Bramness JG (2021)
Subjective symptoms and serum methadone concentrations: what should guide dose adjustments in methadone maintenance treatment? A naturalistic cohort study from Norway
Subst Abuse Treat Prev Policy, 16 (1), 39
DOI 10.1186/s13011-021-00367-w, PubMed 33941217

Cheng K, Bleka Ø, Gill P, Curran J, Bright JA, Taylor D, Buckleton J (2021)
A comparison of likelihood ratios obtained from EuroForMix and STRmix™
J Forensic Sci
DOI 10.1111/1556-4029.14886, PubMed 34553371

Degerud E, Høiseth G, Mørland J, Ariansen I, Graff-Iversen S, Ystrom E, Zuccolo L, Tell GS, Næss Ø (2021)
Associations of Binge Drinking With the Risks of Ischemic Heart Disease and Stroke: A Study of Pooled Norwegian Health Surveys
Am J Epidemiol, 190 (8), 1592-1603
DOI 10.1093/aje/kwab063, PubMed 33720294

Eidahl JML, Stray-Pedersen A, Rognum TO, Opdal SH (2021)
Aquaporin 4 expression in the hippocampus in sudden infant death syndrome and sudden unexplained death in childhood
J Chem Neuroanat, 115, 101962
DOI 10.1016/j.jchemneu.2021.101962, PubMed 33945852

Engebretsen S, Bogstrand ST, Jacobsen D, Rimstad R (2021)
Quality of care, resource use and patient outcome by use of emergency response team compared with standard care for critically ill medical patients in the emergency department: a retrospective single-centre cohort study from Norway
BMJ Open, 11 (8), e047264
DOI 10.1136/bmjopen-2020-047264, PubMed 34385247

Gill P, Benschop C, Buckleton J, Bleka Ø, Taylor D (2021)
A Review of Probabilistic Genotyping Systems: EuroForMix, DNAStatistX and STRmix™
Genes (Basel), 12 (10)
DOI 10.3390/genes12101559, PubMed 34680954

Gill P, Bleka Ø, Roseth A, Fonneløp AE (2021)
An LR framework incorporating sensitivity analysis to model multiple direct and secondary transfer events on skin surface
Forensic Sci Int Genet, 53, 102509
DOI 10.1016/j.fsigen.2021.102509, PubMed 33930816

Gjerde H, Bretteville-Jensen AL, Bache-Andreassen L, Hanoa K, Furuhaugen H, Brochmann GW, Vindenes V (2021)
Which illicit drugs are injected in Oslo? A study based on analysis of drug residues in used injection equipment and self-reported information
Scand J Public Health, 14034948211043984
DOI 10.1177/14034948211043984, PubMed 34538164

Havig SM, Vindenes V, Øiestad ÅML, Rogde S, Thaulow CH (2021)
Methadone, Buprenorphine, Oxycodone, Fentanyl, and Tramadol in Multiple Postmortem Matrices
J Anal Toxicol (in press)
DOI 10.1093/jat/bkab071, PubMed 34115841

Høiseth G, Hilberg T, Trydal T, Husa A, Vindenes V, Bogstrand ST (2021)
The alcohol marker phosphatidylethanol is closely related to AST, GGT, ferritin and HDL-C
Basic Clin Pharmacol Toxicol (in press)
DOI 10.1111/bcpt.13662, PubMed 34591374

Hole K, Arnestad M, Molden E, Haslemo T (2021)
Dose-Dependent Inhibition of CYP2D6 by Bupropion in Patients With Depression
J Clin Psychopharmacol, 41 (3), 281-285
DOI 10.1097/JCP.0000000000001387, PubMed 33905640

Johannessen H, Gill P, Roseth A, Fonneløp AE (2021)
Determination of shedder status: A comparison of two methods involving cell counting in fingerprints and the DNA analysis of handheld tubes
Forensic Sci Int Genet, 53, 102541
DOI 10.1016/j.fsigen.2021.102541, PubMed 34090062

Johanson SM, Ropstad E, Østby GC, Aleksandersen M, Zamaratskaia G, Boge GS, Halsne R, Trangerud C, Lyche JL, Berntsen HF, Zimmer KE, Verhaegen S (2021)
Perinatal exposure to a human relevant mixture of persistent organic pollutants: Effects on mammary gland development, ovarian folliculogenesis and liver in CD-1 mice
PLoS One, 16 (6), e0252954
DOI 10.1371/journal.pone.0252954, PubMed 34111182

Jørgenrud B, Furuhaugen H, Gjerde H (2021)
Prevalence and Correlates of Illicit Drug Use among Norwegian Nightlife Patrons
Subst Use Misuse, 56 (11), 1697-1706
DOI 10.1080/10826084.2021.1949613, PubMed 34251973

Jørgenrud B, Kabashi S, Nadezhdin A, Bryun E, Koshkina E, Tetenova E, Lerdal A, Norby G, Kolgashkin A, Petukhov A, Perekhodov S, Davydova E, Vindenes V, Gamboa D, Bogstrand ST (2021)
The Association between the Alcohol Biomarker Phosphatidylethanol (PEth) and Self-Reported Alcohol Consumption among Russian and Norwegian Medical Patients
Alcohol Alcohol (in press)
DOI 10.1093/alcalc/agab013, PubMed 33677484

Kling D, Phillips C, Kennett D, Tillmar A (2021)
Investigative genetic genealogy: Current methods, knowledge and practice
Forensic Sci Int Genet, 52, 102474
DOI 10.1016/j.fsigen.2021.102474, PubMed 33592389

Langberg C, Hadley CL, Midtervoll M, Edvardsen HME, Molden E, Shafiei M, Jacobsen D (2021)
Quetiapine Poisoning - Epidemiology, Toxicokinetics and Review of the Literature
Lupine Online Journal of Medical Sciences, 5 (5), 565-573
PublikaID 372

Mestad IO, Gjelstad A, Pedersen-Bjergaard S, Oiestad EL (2021)
Green and sustainable drug analysis-Combining microsampling and microextraction of drugs of abuse
SUSTAIN. CHEM. PHARM., 24, 100517
DOI 10.1016/j.scp.2021.100517

Midtlyng L, Høiseth G, Luytkis H, Kristoffersen L, Le Nygaard I, Strand MC, Arnestad M, Vevelstad M (2021)
Relationship between betahydroxybutyrate (BHB) and acetone concentrations in postmortem blood and cause of death
Forensic Sci Int, 321, 110726
DOI 10.1016/j.forsciint.2021.110726, PubMed 33631622

Mygind L, Bergh MS, Tejsi V, Vaitheeswaran R, Lambertsen KL, Finsen B, Metaxas A (2021)
Tumor Necrosis Factor (TNF) Is Required for Spatial Learning and Memory in Male Mice under Physiological, but Not Immune-Challenged Conditions
Cells, 10 (3)
DOI 10.3390/cells10030608, PubMed 33803476

Opdal SH, Ferrante L, Rognum TO, Stray-Pedersen A (2021)
Aquaporin-1 and aquaporin-9 gene variations in sudden infant death syndrome
Int J Legal Med, 135 (3), 719-725
DOI 10.1007/s00414-020-02493-9, PubMed 33462668

Osberg S, Kalstad TG, Stray-Pedersen A (2021)
Norwegian parents avoid placing infants in prone sleeping positions but frequently share beds in hazardous ways
Acta Paediatr, 110 (7), 2119-2125
DOI 10.1111/apa.15797, PubMed 33544951

Oyono Y, Gjerde H, Acha Asongalem E, Kouomogne Nteungue BA, Bamuh E, Deuwa Ngako A, Kelley-Baker T, Ramaekers JG, Lontsi Sonwa L, Enow-Orock G, Achidi Akum E (2021)
Roadside surveys of drinking and driving in Cameroon
Traffic Inj Prev, 22 (5), 349-354
DOI 10.1080/15389588.2021.1922682, PubMed 34014768

Pasnin LT, Gjerde H (2021)
Alcohol and drug use among road users involved in fatal crashes in Norway
Traffic Inj Prev, 22 (4), 267-271
DOI 10.1080/15389588.2021.1887854, PubMed 33724110

Sidqey D, Liane VH, Kristoffersen L (2021)
Quantitative Determination of Ethyl Glucuronide and Ethyl Sulfate in Postmortem and Antemortem Whole Blood Using Phospholipid Removal 96-Well Plate and UHPLC-MS-MS
J Anal Toxicol, 45 (4), 378-388
DOI 10.1093/jat/bkaa108, PubMed 32816025

Skaalvik TG, Øiestad EL, Trones R, Pedersen-Bjergaard S, Hegstad S (2021)
Determination of psychoactive drugs in serum using conductive vial electromembrane extraction combined with UHPLC-MS/MS
J Chromatogr B Analyt Technol Biomed Life Sci, 1183, 122926
DOI 10.1016/j.jchromb.2021.122926, PubMed 34624684

Skottvoll FS, Hansen FA, Harrison S, Boger IS, Mrsa A, Restan MS, Stein M, Lundanes E, Pedersen-Bjergaard S, Aizenshtadt A, Krauss S, Sullivan G, Bogen IL, Wilson SR (2021)
Electromembrane Extraction and Mass Spectrometry for Liver Organoid Drug Metabolism Studies
Anal Chem, 93 (7), 3576-3585
DOI 10.1021/acs.analchem.0c05082, PubMed 33534551

Stray-Pedersen A, Strisland F, Rognum TO, Schiks LAH, Loeve AJ (2021)
Violent Infant Surrogate Shaking: Continuous High-Magnitude Centripetal Force and Abrupt Shift in Tangential Acceleration May Explain High Risk of Subdural Hemorrhage
Neurotrauma Rep, 2 (1), 224-231
DOI 10.1089/neur.2021.0013, PubMed 34223553

Sundet M, Mulima G, Kajombo C, Gjerde H, Christophersen AS, Madsen JE, Young S (2021)
Geographical mapping of road traffic injuries in Lilongwe, Malawi
Injury, 52 (4), 806-813
DOI 10.1016/j.injury.2021.02.028, PubMed 33712299

Tveito M, Høiseth G, Haslemo T, Molden E, Smith RL (2021)
Impact of age and gender on paliperidone exposure in patients after administration of long-acting injectable formulations-an observational study using blood samples from 1223 patients
Eur J Clin Pharmacol, 77 (8), 1201-1208
DOI 10.1007/s00228-021-03114-z, PubMed 33616704

Tverdal A, Høiseth G, Magnus P, Næss Ø, Selmer R, Knudsen GP, Mørland J (2021)
Alcohol Consumption, HDL-Cholesterol and Incidence of Colon and Rectal Cancer: A Prospective Cohort Study Including 250,010 Participants
Alcohol Alcohol (in press)
DOI 10.1093/alcalc/agab007, PubMed 33604595

Vollmer-Sandholm MJ, Myhre AK, Otterman G, Lydersen S, Stray-Pedersen A (2021)
Amongst Norwegian paediatricians there is little agreement in management of cases of suspected child maltreatment
Acta Paediatr, 110 (10), 2865-2872
DOI 10.1111/apa.16017, PubMed 34214215

Wang S, Shanthan G, Bouzga MM, Thi Dinh HM, Haas C, Fonneløp AE (2021)
Evaluating the performance of five up-to-date DNA/RNA co-extraction methods for forensic application
Forensic Sci Int, 328, 110996
DOI 10.1016/j.forsciint.2021.110996, PubMed 34592582

Wiedmann M, Skattør T, Stray-Pedersen A, Romundstad L, Antal EA, Marthinsen PB, Sørvoll IH, Leiknes Ernstsen S, Lund CG, Holme PA, Johansen TO, Brunborg C, Aamodt AH, Schultz NH, Skagen K, Skjelland M (2021)
Vaccine Induced Immune Thrombotic Thrombocytopenia Causing a Severe Form of Cerebral Venous Thrombosis With High Fatality Rate: A Case Series
Front Neurol, 12, 721146
DOI 10.3389/fneur.2021.721146, PubMed 34393988

Wilson T, Wisborg T, Vindenes V, Jamt RG, Furuhaugen H, Bogstrand ST (2021)
Psychoactive substances have major impact on injuries in rural arctic Norway - A prospective observational study
Acta Anaesthesiol Scand, 65 (6), 824-833
DOI 10.1111/aas.13807, PubMed 33638866

Zosen D, Hadera MG, Lumor JS, Andersen JM, Paulsen RE (2021)
Chicken embryo as animal model to study drug distribution to the developing brain
J Pharmacol Toxicol Methods, 112, 107105 (in press)
DOI 10.1016/j.vascn.2021.107105, PubMed 34284116

 
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