Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2017 from OUS - Division of Head, Neck and Reconstructive Surgery
67 publications found
Idiopathic subglottic stenosis: an epidemiological single-center study
Eur Arch Otorhinolaryngol, 274 (5), 2225-2228
DOI 10.1007/s00405-017-4512-0, PubMed 28243785
Establishment of a tear protein biomarker panel differentiating between Graves' disease with or without orbitopathy
PLoS One, 12 (4), e0175274
DOI 10.1371/journal.pone.0175274, PubMed 28419103
Pre-diagnostic dynamic HPV16 IgG seropositivity and risk of oropharyngeal cancer
Oral Oncol, 73, 132-137
DOI 10.1016/j.oraloncology.2017.08.014, PubMed 28939065
Identification of potential saliva and tear biomarkers in primary Sjögren's syndrome, utilising the extraction of extracellular vesicles and proteomics analysis
Arthritis Res Ther, 19 (1), 14
DOI 10.1186/s13075-017-1228-x, PubMed 28122643
Hypoxia and inflammation in the release of VEGF and interleukins from human retinal pigment epithelial cells
Graefes Arch Clin Exp Ophthalmol, 255 (9), 1757-1762
DOI 10.1007/s00417-017-3711-0, PubMed 28631245
Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 3. Descriptive study of postoperative nursing care following first stage cleft closure
J Plast Surg Hand Surg, 51 (1), 21-26
DOI 10.1080/2000656X.2016.1269776, PubMed 28218561
An 8-year follow-up of anti-vascular endothelial growth factor treatment with a treat-and-extend modality for neovascular age-related macular degeneration
Acta Ophthalmol, 95 (8), 796-802
DOI 10.1111/aos.13522, PubMed 28926190
Parkinson's disease; the hibernating spore hypothesis
Med Hypotheses, 104, 48-53
DOI 10.1016/j.mehy.2017.05.022, PubMed 28673590
Corrigendum: Antibody-antigen kinetics constrain intracellular humoral immunity
Sci Rep, 7, 45418
DOI 10.1038/srep45418, PubMed 28382939
Impact of stage, management and recurrence on survival rates in laryngeal cancer
PLoS One, 12 (7), e0179371
DOI 10.1371/journal.pone.0179371, PubMed 28708883
Meibomian gland features in a Norwegian cohort of patients with primary Sjögren´s syndrome
PLoS One, 12 (9), e0184284
DOI 10.1371/journal.pone.0184284, PubMed 28886085
Prevalence of Age-Related Macular Degeneration in Europe: The Past and the Future
Ophthalmology, 124 (12), 1753-1763
DOI 10.1016/j.ophtha.2017.05.035, PubMed 28712657
Fatigue and cognition: Pupillary responses to problem-solving in early multiple sclerosis patients
Brain Behav, 7 (7), e00717
DOI 10.1002/brb3.717, PubMed 28729927
Hysterectomy at St. Olavs hospital 1989-2014
Tidsskr. Nor. Laegeforen., 137 (16), 1191-1196
[Hysterectomy at St. Olavs Hospital 1989-2014]
Tidsskr Nor Laegeforen, 137 (16)
DOI 10.4045/tidsskr.16.0260, PubMed 28871734
A multicenter, prospective, noninterventional study in a Norwegian cohort of patients with moderate-to-severe allergic rhinitis treated with MP-AzeFlu
Allergy Rhinol (Providence), 8 (3), 148-156
DOI 10.2500/ar.2017.8.0216, PubMed 29070272
Relationship between retinal vessel diameters and retinopathy in the Inter99 Eye Study
J Clin Transl Endocrinol, 8, 22-28
DOI 10.1016/j.jcte.2017.03.002, PubMed 29067255
The Results of Stricter Inclusion Criteria in an Immunomagnetic Detection Study of Micrometastatic Cells in Bone Marrow of Uveal Melanoma Patients - Relevance for Dormancy
Pathol Oncol Res, 25 (1), 255-262
DOI 10.1007/s12253-017-0355-7, PubMed 29098521
Scandcleft randomised trials of primary surgery for unilateral cleft lip and Palate: 9. Parental report of social and emotional experiences related to their 5-year-old child's cleft diagnosis
J Plast Surg Hand Surg, 51 (1), 73-80
DOI 10.1080/2000656X.2016.1254643, PubMed 28218553
Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 10. Parental perceptions of appearance and treatment outcomes in their 5-year-old child
J Plast Surg Hand Surg, 51 (1), 81-87
DOI 10.1080/2000656X.2016.1254642, PubMed 28218558
Adults with 22q11.2 deletion syndrome have a different velopharyngeal anatomy with predisposition to velopharyngeal insufficiency
J Plast Reconstr Aesthet Surg, 71 (4), 524-536
DOI 10.1016/j.bjps.2017.09.006, PubMed 29032918
Human papillomavirus in oropharyngeal squamous cell carcinoma in South-Eastern Norway: prevalence, genotype, and survival
Eur Arch Otorhinolaryngol, 274 (11), 4003-4010
DOI 10.1007/s00405-017-4748-8, PubMed 28933005
Identification of Objective Morphometric Markers of Xerostomia in the Oral Mucosa Epithelium with In Vivo Confocal Microscopy
Microsc Microanal, 23 (1), 88-96
DOI 10.1017/S1431927617000022, PubMed 28162126
Vitreous hyper-reflective dots in pseudophakic cystoid macular edema assessed with optical coherence tomography
PLoS One, 12 (12), e0189194
DOI 10.1371/journal.pone.0189194, PubMed 29244855
Lugol's solution eradicates Staphylococcus aureus biofilm in vitro
Int J Pediatr Otorhinolaryngol, 103, 58-64
DOI 10.1016/j.ijporl.2017.09.025, PubMed 29224767
Collagen crosslinking with conventional and accelerated ultraviolet-A irradiation using riboflavin with hydroxypropyl methylcellulose
J Cataract Refract Surg, 43 (4), 511-517
DOI 10.1016/j.jcrs.2017.01.013, PubMed 28532937
EUFOREA Rhinology Research Forum 2016: report of the brainstorming sessions on needs and priorities in rhinitis and rhinosinusitis
Rhinology, 55 (3), 202-210
DOI 10.4193/Rhin17.028, PubMed 28501885
Hand, shoulder and back stiffness in long-term type 1 diabetes; cross-sectional association with skin collagen advanced glycation end-products. The Dialong study
J Diabetes Complications, 31 (9), 1408-1414
DOI 10.1016/j.jdiacomp.2017.06.007, PubMed 28705609
Panel 1: Epidemiology and Diagnosis
Otolaryngol Head Neck Surg, 156 (4_suppl), S1-S21
DOI 10.1177/0194599816643510, PubMed 28372531
Comparative proteomic analysis of human embryonic stem cell-derived and primary human retinal pigment epithelium
Sci Rep, 7 (1), 6016
DOI 10.1038/s41598-017-06233-9, PubMed 28729539
CB2 receptor activation causes an ERK1/2-dependent inflammatory response in human RPE cells
Sci Rep, 7 (1), 16169
DOI 10.1038/s41598-017-16524-w, PubMed 29170454
Two dietary polyphenols, fisetin and luteolin, reduce inflammation but augment DNA damage-induced toxicity in human RPE cells
J Nutr Biochem, 42, 37-42
DOI 10.1016/j.jnutbio.2016.12.014, PubMed 28113103
Donor-Site Morbidity After DIEAP Flap Breast Reconstruction-A 2-Year Postoperative Computed Tomography Comparison
Plast Reconstr Surg Glob Open, 5 (7), e1405
DOI 10.1097/GOX.0000000000001405, PubMed 28831346
Tissue Harvesting Site and Culture Medium Affect Attachment, Growth, and Phenotype of Ex Vivo Expanded Oral Mucosal Epithelial Cells
Sci Rep, 7 (1), 674
DOI 10.1038/s41598-017-00417-z, PubMed 28386069
Optimization of Storage Temperature for Retention of Undifferentiated Cell Character of Cultured Human Epidermal Cell Sheets
Sci Rep, 7 (1), 8206
DOI 10.1038/s41598-017-08586-7, PubMed 28811665
Cultured epidermal stem cells in regenerative medicine
Stem Cell Res Ther, 8 (1), 155
DOI 10.1186/s13287-017-0587-1, PubMed 28676094
Anaplastic thyroid cancer and hyperfractionated accelerated radiotherapy (HART) with and without surgery
Eur Arch Otorhinolaryngol, 274 (12), 4203-4209
DOI 10.1007/s00405-017-4764-8, PubMed 29019001
Adverse Health Outcomes and Associations with Self-Reported General Health in Childhood Lymphoma Survivors
J Adolesc Young Adult Oncol, 6 (3), 470-476
DOI 10.1089/jayao.2017.0018, PubMed 28837384
Proliferative Cells Isolated from the Adult Human Peripheral Retina only Transiently Upregulate Key Retinal Markers upon Induced Differentiation
Curr Eye Res, 43 (3), 340-349
DOI 10.1080/02713683.2017.1403630, PubMed 29161152
Two-year functional and anatomical results after converting treatment resistant eyes with exudative age-related macular degeneration to aflibercept in accordance with a treat and extend protocol
Acta Ophthalmol, 95 (5), 460-463
DOI 10.1111/aos.13480, PubMed 28556485
Cultivation and characterization of pterygium as an ex vivo study model for disease and therapy
Cont Lens Anterior Eye, 40 (5), 283-292
DOI 10.1016/j.clae.2017.04.002, PubMed 28550976
Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 7. Occlusion in 5 year-olds according to the Huddart and Bodenham index
J Plast Surg Hand Surg, 51 (1), 58-63
DOI 10.1080/2000656X.2016.1265529, PubMed 28218557
Olfactory neuroblastoma: a single-center experience
Neurosurg Rev, 41 (1), 323-331
DOI 10.1007/s10143-017-0859-3, PubMed 28540633
Astigmatism and Refractive Outcome After Late In-The-Bag Intraocular Lens Dislocation Surgery: A Randomized Clinical Trial
Invest Ophthalmol Vis Sci, 58 (11), 4747-4753
DOI 10.1167/iovs.17-22723, PubMed 28973318
Glaucoma and Intraocular Pressure in Patients Operated for Late In-the-bag Intraocular Lens Dislocation: A Randomized Clinical Trial
Am J Ophthalmol, 176, 219-227
DOI 10.1016/j.ajo.2017.01.026, PubMed 28167054
The genetics of congenital aniridia-a guide for the ophthalmologist
Surv Ophthalmol, 63 (1), 105-113
DOI 10.1016/j.survophthal.2017.09.004, PubMed 28923585
Conjunctival provocation test in diagnosis of peanut allergy in children
Clin Exp Allergy, 47 (6), 785-794
DOI 10.1111/cea.12899, PubMed 28160326
Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 4. Speech outcomes in 5-year-olds - velopharyngeal competency and hypernasality
J Plast Surg Hand Surg, 51 (1), 27-37
DOI 10.1080/2000656X.2016.1254645, PubMed 28218551
Comparative cyto-histological study of needle tip aspirates and entry sites after intravitreal injection using different needle types
PLoS One, 12 (7), e0174467
DOI 10.1371/journal.pone.0174467, PubMed 28692684
Fundus imaging in newborn children with wide-field scanning laser ophthalmoscope
Acta Ophthalmol, 95 (8), 842-844
DOI 10.1111/aos.13453, PubMed 28391630
The proteomic profile of a mouse model of proliferative vitreoretinopathy
FEBS Open Bio, 7 (8), 1166-1177
DOI 10.1002/2211-5463.12252, PubMed 28781956
Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 8. Assessing naso-labial appearance in 5-year-olds - a preliminary study
J Plast Surg Hand Surg, 51 (1), 64-72
DOI 10.1080/2000656X.2016.1266492, PubMed 28218555
Sequential Bilateral Cochlear Implantation in Children: Outcome of the Second Implant and Long-Term Use
Ear Hear, 38 (3), 301-313
DOI 10.1097/AUD.0000000000000383, PubMed 27828788
Cultivation and characterisation of the surface markers and carbohydrate profile of human corneal endothelial cells
Clin Exp Ophthalmol, 45 (5), 509-519
DOI 10.1111/ceo.12903, PubMed 28032398
Effect of Isolation Technique and Location on the Phenotype of Human Corneal Stroma-Derived Cells
Stem Cells Int, 2017, 9275248
DOI 10.1155/2017/9275248, PubMed 29213290
Multicellular tumor spheroids of human uveal melanoma induce genes associated with anoikis resistance, lipogenesis, and SSXs
Mol Vis, 23, 680-694
PubMed 29033534
Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 2. Surgical results
J Plast Surg Hand Surg, 51 (1), 14-20
DOI 10.1080/2000656X.2016.1254646, PubMed 28218552
Guidelines for the Management of Diabetic Macular Edema by the European Society of Retina Specialists (EURETINA)
Ophthalmologica, 237 (4), 185-222
DOI 10.1159/000458539, PubMed 28423385
A Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 1. Planning and management
J Plast Surg Hand Surg, 51 (1), 2-13
DOI 10.1080/2000656X.2016.1263202, PubMed 28218559
The Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 11. What next?
J Plast Surg Hand Surg, 51 (1), 88-93
DOI 10.1080/2000656X.2016.1254644, PubMed 28218554
Long-term ototoxicity in women after cisplatin treatment for ovarian germ cell cancer
Gynecol Oncol, 145 (1), 148-153
DOI 10.1016/j.ygyno.2017.02.006, PubMed 28202195
Ex vivo 3D human corneal stroma model for Schnyder corneal dystrophy - role of autophagy in its pathogenesis and resolution
Histol Histopathol, 33 (5), 455-462
DOI 10.14670/HH-11-928, PubMed 28872183
A woman in her 50s with chronic fatigue syndrome, sepsis and hyponatraemia
Tidsskr Nor Laegeforen, 137 (5), 372-377
DOI 10.4045/tidsskr.16.0896, PubMed 28272569
Measuring the depth of crosslinking demarcation line in vivo: Comparison of methods and devices
J Cataract Refract Surg, 43 (2), 255-262
DOI 10.1016/j.jcrs.2017.01.003, PubMed 28366375
Prostaglandin E1 Increases Microcirculation in Random Pattern Flaps on Rats Measured with Laser Doppler Perfusion Imaging
Plast Reconstr Surg Glob Open, 5 (1), e1202
DOI 10.1097/GOX.0000000000001202, PubMed 28203503
Does a lack of auditory experience affect sequential learning?
Cognition, 170, 123-129
DOI 10.1016/j.cognition.2017.09.017, PubMed 28988151
Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 5. Speech outcomes in 5-year-olds - consonant proficiency and errors
J Plast Surg Hand Surg, 51 (1), 38-51
DOI 10.1080/2000656X.2016.1254647, PubMed 28218556