Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2020 from OUS - Rheumatology Research Group

23 publications found

Benvenuti F, Zanatta E, Avouac J, Müller-Ladner U, Cozzi F, Hoffmann-Vold AM, Gabrielli A, Distler O, Matucci-Cerinic M, Allanore Y, Doria A (2020)
The power of the EUSTAR cohort: key findings to date and implications for management of systemic sclerosis patients
Expert Rev Clin Immunol, 16 (11), 1065-1074
DOI 10.1080/1744666X.2021.1836962, PubMed 33076716

Berntsen KS, Raastad T, Marstein H, Kirkhus E, Merckoll E, Cumming KT, Flatø B, Sjaastad I, Sanner H (2020)
Functional and Structural Adaptations of Skeletal Muscle in Long-Term Juvenile Dermatomyositis: A Controlled Cross-Sectional Study
Arthritis Rheumatol, 72 (5), 837-848
DOI 10.1002/art.41174, PubMed 31746550

Distler O, Assassi S, Cottin V, Cutolo M, Danoff SK, Denton CP, Distler JHW, Hoffmann-Vold AM, Johnson SR, Müller Ladner U, Smith V, Volkmann ER, Maher TM (2020)
Predictors of progression in systemic sclerosis patients with interstitial lung disease
Eur Respir J, 55 (5)
DOI 10.1183/13993003.02026-2019, PubMed 32079645

Durheim MT, Hoffmann-Vold AM, Eagan TM, Hovden AO, Lund MB, Bjerke G, Birring SS, Jonassen TM, Johansen OE, Sjåheim T (2020)
ILD-specific health-related quality of life in systemic sclerosis-associated ILD compared with IPF
BMJ Open Respir Res, 7 (1)
DOI 10.1136/bmjresp-2020-000598, PubMed 32576559

Fretheim H, Chung BK, Didriksen H, Bækkevold ES, Midtvedt Ø, Brunborg C, Holm K, Valeur J, Tennøe AH, Garen T, Midtvedt T, Trøseid M, Zarè H, Lund MB, Hov JR, Lundin KEA, Molberg Ø, Hoffmann-Vold AM (2020)
Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
PLoS One, 15 (5), e0232739
DOI 10.1371/journal.pone.0232739, PubMed 32437393

Fretheim H, Halse AK, Seip M, Bitter H, Wallenius M, Garen T, Salberg A, Brunborg C, Midtvedt Ø, Molberg Ø, Hoffmann-Vold AM (2020)
Multidimensional tracking of phenotypes and organ involvement in a complete nationwide systemic sclerosis cohort
Rheumatology (Oxford), 59 (10), 2920-2929
DOI 10.1093/rheumatology/keaa026, PubMed 32097470

Frid P, Augdal TA, Larheim TA, Halbig J, Rypdal V, Songstad NT, Rosén A, Tylleskär KB, Berstad JR, Flatø B, Stoustrup P, Rosendahl K, Kirkhus E, Nordal E (2020)
Efficacy and safety of intraarticular corticosteroid injections in adolescents with juvenile idiopathic arthritis in the temporomandibular joint: a Norwegian 2-year prospective multicenter pilot study
Pediatr Rheumatol Online J, 18 (1), 75
DOI 10.1186/s12969-020-00464-3, PubMed 32998740

Frid P, Baraniya D, Halbig J, Rypdal V, Songstad NT, Rosèn A, Berstad JR, Flatø B, Alakwaa F, Gil EG, Cetrelli L, Chen T, Al-Hebshi NN, Nordal E, Al-Haroni M (2020)
Salivary Oral Microbiome of Children With Juvenile Idiopathic Arthritis: A Norwegian Cross-Sectional Study
Front Cell Infect Microbiol, 10, 602239
DOI 10.3389/fcimb.2020.602239, PubMed 33251163

Giancane G, Swart JF, Castagnola E, Groll AH, Horneff G, Huppertz HI, Lovell DJ, Wolfs T, Herlin T, Dolezalova P, Sanner H, Susic G, Sztajnbok F, Maritsi D, Constantin T, Vargova V, Sawhney S, Rygg M, K Oliveira S, Cattalini M, Bovis F, Bagnasco F, Pistorio A, Martini A, Wulffraat N et al. (2020)
Opportunistic infections in immunosuppressed patients with juvenile idiopathic arthritis: analysis by the Pharmachild Safety Adjudication Committee
Arthritis Res Ther, 22 (1), 71
DOI 10.1186/s13075-020-02167-2, PubMed 32264969

Hoffmann-Vold AM, Allanore Y, Alves M, Brunborg C, Airó P, Ananieva LP, Czirják L, Guiducci S, Hachulla E, Li M, Mihai C, Riemekasten G, Sfikakis PP, Kowal-Bielecka O, Riccardi A, Distler O, EUSTAR collaborators (2020)
Progressive interstitial lung disease in patients with systemic sclerosis-associated interstitial lung disease in the EUSTAR database
Ann Rheum Dis, 80 (2), 219-227
DOI 10.1136/annrheumdis-2020-217455, PubMed 32988845

Hoffmann-Vold AM, Allanore Y, Bendstrup E, Bruni C, Distler O, Maher TM, Wijsenbeek M, Kreuter M (2020)
The need for a holistic approach for SSc-ILD - achievements and ambiguity in a devastating disease
Respir Res, 21 (1), 197
DOI 10.1186/s12931-020-01459-0, PubMed 32703199

Hoffmann-Vold AM, Fretheim H, Meier C, Maurer B (2020)
Circulating biomarkers of systemic sclerosis - interstitial lung disease
J. Scleroderma Relat. Disord., 5 (2_SUPPL 2_), 2397198319894851-47

Hoffmann-Vold AM, Maher TM, Philpot EE, Ashrafzadeh A, Barake R, Barsotti S, Bruni C, Carducci P, Carreira PE, Castellvi I, Del Galdo F, Distler JHW, Foeldvari I, Fraticelli P, George PM, Griffiths B, Guillen-Del-Castillo A, Hamid AM, Horvath R, Hughes M, Kreuter M, Moazedi-Fuerst F, Olas J, Paul S, Rotondo C et al. (2020)
The identification and management of interstitial lung disease in systemic sclerosis: evidence-based European consensus statements
Lancet Rheumatol., 2 (2), E71-E83

Hoffmann-Vold AM, Molberg Ø (2020)
Detection, screening, and classification of interstitial lung disease in patients with systemic sclerosis
Curr Opin Rheumatol, 32 (6), 497-504
DOI 10.1097/BOR.0000000000000741, PubMed 32890027

Holme SS, Moen JM, Kilian K, Eggesbø HB, Molberg Ø (2020)
Impact of Paranasal Sinus Surgery in Granulomatosis With Polyangiitis: A Longitudinal Computed Tomography Study
Laryngoscope, 130 (8), E460-E468
DOI 10.1002/lary.28639, PubMed 32243590

Lemmers JMJ, Fretheim H, Knaapen HKA, van den Hoogen FHJ, Van Haren-Willems JHGM, Duijnhouwer AL, van Dijk AP, van den Ende CHM, Hoffmann-Vold AM, Vonk MC (2020)
Selexipag treatment in patients with systemic sclerosis-associated pulmonary arterial hypertension in clinical practice, a case series
J. Scleroderma Relat. Disord., 5 (3), 2397198320916082-NP11

Malattia C, Ruperto N, Pederzoli S, Palmisani E, Pistorio A, Wouters C, Dolezalova P, Flato B, Garay S, Giancane G, Wells C, Douglass W, Brunner HI, De Benedetti F, Ravelli A, Paediatric Rheumatology International Trials Organisation (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG) (2020)
Tocilizumab may slow radiographic progression in patients with systemic or polyarticular-course juvenile idiopathic arthritis: post hoc radiographic analysis from two randomized controlled trials
Arthritis Res Ther, 22 (1), 211
DOI 10.1186/s13075-020-02303-y, PubMed 32912276

Marstein H, Schwartz T, Aaløkken TM, Lund MB, Flatø B, Sjaastad I, Sanner H (2020)
Novel associations between cytokines and pulmonary involvement in juvenile dermatomyositis - a cross-sectional study of long-term disease
Rheumatology (Oxford), 59 (8), 1862-1870
DOI 10.1093/rheumatology/kez531, PubMed 31740970

Olson A, Hartmann N, Patnaik P, Wallace L, Schlenker-Herceg R, Nasser M, Richeldi L, Hoffmann-Vold AM, Cottin V (2020)
Estimation of the Prevalence of Progressive Fibrosing Interstitial Lung Diseases: Systematic Literature Review and Data from a Physician Survey
Adv Ther, 38 (2), 854-867
DOI 10.1007/s12325-020-01578-6, PubMed 33315170

Ossum AM, Palm Ø, Cvancarova M, Bernklev T, Jahnsen J, Moum B, Høivik ML, IBSEN Study Group (2020)
The Impact of Spondyloarthritis and Joint Symptoms on Health-Related Quality of Life and Fatigue in IBD Patients. Results From a Population-Based Inception Cohort (20-Year Follow-up in the Ibsen Study)
Inflamm Bowel Dis, 26 (1), 114-124
DOI 10.1093/ibd/izz105, PubMed 31127829

Sandling JK, Pucholt P, Hultin Rosenberg L, Farias FHG, Kozyrev SV, Eloranta ML, Alexsson A, Bianchi M, Padyukov L, Bengtsson C, Jonsson R, Omdal R, Lie BA, Massarenti L, Steffensen R, Jakobsen MA, Lillevang ST, ImmunoArray Development Consortium and DISSECT consortium, Lerang K, Molberg Ø, Voss A, Troldborg A, Jacobsen S, Syvänen AC, Jönsen A et al. (2020)
Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing
Ann Rheum Dis, 80 (1), 109-117
DOI 10.1136/annrheumdis-2020-218636, PubMed 33037003

Spagnolo P, Distler O, Ryerson CJ, Tzouvelekis A, Lee JS, Bonella F, Bouros D, Hoffmann-Vold AM, Crestani B, Matteson EL (2020)
Mechanisms of progressive fibrosis in connective tissue disease (CTD)-associated interstitial lung diseases (ILDs)
Ann Rheum Dis, 80 (2), 143-150
DOI 10.1136/annrheumdis-2020-217230, PubMed 33037004

Tashbayev B, Garen T, Palm Ø, Chen X, Herlofson BB, Young A, Hove LH, Rykke M, Singh PB, Aqrawi LA, Utheim ØA, Utheim TP, Jensen JL (2020)
Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study
Sci Rep, 10 (1), 2063
DOI 10.1038/s41598-020-59078-0, PubMed 32034249

 
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