Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2021 from OUS - Dept. of Gastroenterology RH (Div SIMT)

29 publications found

Antonelli G, Karsensten JG, Bhat P, Ijoma U, Osuagwu C, Desalegn H, Abera H, Guy C, Vilmann P, Dinis-Ribeiro M, Ponchon T, Sabbagh LC, Pausawasdi N, Makharia G, Hassan C, Veitch A, Aabakken L, Ebigbo A, Endoscopy and COVID-19 Cascade Working Group, European Society of Gastrointestinal Endoscopy, World Endoscopy Organization and World Gastroenterology Organization (2021)
Resuming endoscopy during COVID-19 pandemic: ESGE, WEO and WGO Joint Cascade Guideline for Resource Limited Settings
Endosc Int Open, 9 (4), E543-E551
DOI 10.1055/a-1400-9135, PubMed 33816775

Åvitsland TL, Aabakken L (2021)
Endoscopic retrograde cholangiopancreatography in infants and children
Endosc Int Open, 9 (3), E292-E296
DOI 10.1055/a-1337-2212, PubMed 33655024

Bekkelund M, Sangnes DA, Søfteland E, Aabakken L, Biermann M, Steinsvik EK, Hausken T, Dimcevski G, Hatlebakk JG (2021)
Gastroparesis Symptoms Associated with Intestinal Hypomotility: An Explorative Study Using Wireless Motility Capsule
Clin Exp Gastroenterol, 14, 133-144
DOI 10.2147/CEG.S304854, PubMed 33953592

Bossen L, Vesterhus M, Hov JR, Färkkilä M, Rosenberg WM, Møller HJ, Boberg KM, Karlsen TH, Grønbæk H (2021)
Circulating Macrophage Activation Markers Predict Transplant-Free Survival in Patients With Primary Sclerosing Cholangitis
Clin Transl Gastroenterol, 12 (3), e00315
DOI 10.14309/ctg.0000000000000315, PubMed 33646203

Dahal-Koirala S, Risnes LF, Neumann RS, Christophersen A, Lundin KEA, Sandve GK, Qiao SW, Sollid LM (2021)
Comprehensive Analysis of CDR3 Sequences in Gluten-Specific T-Cell Receptors Reveals a Dominant R-Motif and Several New Minor Motifs
Front Immunol, 12, 639672
DOI 10.3389/fimmu.2021.639672, PubMed 33927715

Dhillon AK, Rupp C, Bergquist A, Voitl R, Folseraas T, Trøseid M, Midttun Ø, Ueland PM, Karlsen TH, Vesterhus M, Kummen M, Hov JR (2021)
Associations of neopterin and kynurenine-tryptophan ratio with survival in primary sclerosing cholangitis
Scand J Gastroenterol, 56 (4), 443-452
DOI 10.1080/00365521.2021.1880627, PubMed 33583308

Fossdal G, Mjelle AB, Wiencke K, Bjørk I, Gilja OH, Folseraas T, Karlsen TH, Rosenberg W, Giil LM, Vesterhus M (2021)
Fluctuating biomarkers in primary sclerosing cholangitis: A longitudinal comparison of alkaline phosphatase, liver stiffness, and ELF
JHEP Rep, 3 (5), 100328
DOI 10.1016/j.jhepr.2021.100328, PubMed 34485881

Frick R, Høydahl LS, Petersen J, du Pré MF, Kumari S, Berntsen G, Dewan AE, Jeliazkov JR, Gunnarsen KS, Frigstad T, Vik ES, Llerena C, Lundin KEA, Yaqub S, Jahnsen J, Gray JJ, Rossjohn J, Sollid LM, Sandlie I, Løset GÅ (2021)
A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation
Sci Immunol, 6 (62)
DOI 10.1126/sciimmunol.abg4925, PubMed 34417258

Goswami N, Fredriksen PM, Lundin KEA, Agu C, Elias SO, Motaung KS, Brix B, Cvirn G, Sourij H, Stelzl E, Kessler HH, Salon A, Nkeh-Chungag B (2021)
COVID-19 and its effects on endothelium in HIV-positive patients in sub-Saharan Africa: Cardiometabolic risk, thrombosis and vascular function (ENDOCOVID STUDY)
BMC Infect Dis, 21 (1), 719
DOI 10.1186/s12879-021-06426-8, PubMed 34332551

Hoff G, Botteri E, Huppertz-Hauss G, Kvamme JM, Holme Ø, Aabakken L, Dahler S, Medhus AW, Blomgren I, Sandvei P, Darre-Næss O, Kjellevold Ø, Seip B (2021)
The effect of train-the-colonoscopy-trainer course on colonoscopy quality indicators
Endoscopy
DOI 10.1055/a-1352-4583, PubMed 33622001

Janson ET, Knigge U, Dam G, Federspiel B, Grønbaek H, Stålberg P, Langer SW, Kjaer A, Arola J, Schalin-Jäntti C, Sundin A, Welin S, Thiis-Evensen E, Sorbye H (2021)
Nordic guidelines 2021 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms
Acta Oncol, 60 (7), 931-941
DOI 10.1080/0284186X.2021.1921262, PubMed 33999752

Jiang X, Bergquist A, Löscher BS, Venkatesh G, Mold JE, Holm K, Laerdahl JK, Skånland SS, Maleki KT, Cornillet M, Taskén K, Franke A, Karlsen TH, Björkström NK, Melum E (2021)
A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
Sci Transl Med, 13 (582)
DOI 10.1126/scitranslmed.abb0036, PubMed 33627483

Juul FE, Jodal HC, Barua I, Refsum E, Olsvik Ø, Helsingen LM, Løberg M, Bretthauer M, Kalager M, Emilsson L (2021)
Mortality in Norway and Sweden during the COVID-19 pandemic
Scand J Public Health, 14034948211047137 (in press)
DOI 10.1177/14034948211047137, PubMed 34609261

Langeland H, Bergum D, Nordseth T, Løberg M, Skaug T, Bjørnstad K, Gundersen Ø, Skjærvold NK, Klepstad P (2021)
Circulatory trajectories after out-of-hospital cardiac arrest: a prospective cohort study
BMC Anesthesiol, 21 (1), 219
DOI 10.1186/s12871-021-01434-2, PubMed 34496748

Leddin D, Omary MB, Veitch A, Metz G, Amrani N, Aabakken L, Ali RAR, Alvares-da-Silva MR, Armstrong D, Boyacioglu S, Chen Y, Elwakil R, Fock KM, Hamid SS, Makharia G, Macrae F, Malekzadeh R, Mulder CJ, Piscoya A, Perman ML, Sadeghi A, Sáenz R, Saurin JC, Butt AS, Wu K et al. (2021)
Uniting the Global Gastroenterology Community to Meet the Challenge of Climate Change and Nonrecyclable Waste
J Clin Gastroenterol, 55 (10), 823-829
DOI 10.1097/MCG.0000000000001619, PubMed 34617932

Leddin D, Omary MB, Veitch A, Metz G, Amrani N, Aabakken L, Raja Ali RA, Alvares-Da-Silva MR, Armstrong D, Boyacioglu S, Chen Y, Elwakil R, Fock KM, Hamid SS, Makharia G, Macrae F, Malekzadeh R, Mulder CJ, Piscoya A, Perman ML, Sadeghi A, Sáenz R, Saurin JC, Butt AS, Wu K et al. (2021)
Uniting the Global Gastroenterology Community to Meet the Challenge of Climate Change and Non-Recyclable Waste
Gastroenterology (in press)
DOI 10.1053/j.gastro.2021.08.001, PubMed 34629165

Leddin D, Omary MB, Veitch A, Metz G, Amrani N, Aabakken L, Raja Ali RA, Alvares-Da-Silva MR, Armstrong D, Boyacioglu S, Chen Y, Elwakil R, Fock KM, Hamid SS, Makharia G, Macrae F, Malekzadeh R, Mulder CJ, Piscoya A, Perman ML, Sadeghi A, Saenz R, Saurin JC, Butt AS, Wu K et al. (2021)
Uniting the global gastroenterology community to meet the challenge of climate change and non-recyclable waste
Gut, 70 (11), 2025-2029
DOI 10.1136/gutjnl-2021-325789, PubMed 34620696

Lindeman I, Zhou C, Eggesbø LM, Miao Z, Polak J, Lundin KEA, Jahnsen J, Qiao SW, Iversen R, Sollid LM (2021)
Longevity, clonal relationship, and transcriptional program of celiac disease-specific plasma cells
J Exp Med, 218 (2)
DOI 10.1084/jem.20200852, PubMed 33095260

Mori Y, Neumann H, Misawa M, Kudo SE, Bretthauer M (2021)
Artificial intelligence in colonoscopy - Now on the market. What's next?
J Gastroenterol Hepatol, 36 (1), 7-11
DOI 10.1111/jgh.15339, PubMed 33179322

Nakanishi T, Pigazzini S, Degenhardt F, Cordioli M, Butler-Laporte G, Maya-Miles D, Bujanda L, Bouysran Y, Niemi ME, Palom A, Ellinghaus D, Khan A, Martínez-Bueno M, Rolker S, Amitrano S, Roade Tato L, Fava F, Spinner CD, Prati D, Bernardo D, Garcia F, Darcis G, Fernandez-Cadenas I, Holter JC, Banales JM et al. (2021)
Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality
J Clin Invest (in press)
DOI 10.1172/JCI152386, PubMed 34597274

Ponsioen CY, Assis DN, Boberg KM, Bowlus CL, Deneau M, Thorburn D, Aabakken L, Färkkilä M, Petersen B, Rupp C, Hübscher SG, Primary Sclerosing Cholangitis Study Group (2021)
Defining Primary Sclerosing Cholangitis: Results From an International Primary Sclerosing Cholangitis Study Group Consensus Process
Gastroenterology (in press)
DOI 10.1053/j.gastro.2021.07.046, PubMed 34384749

Schult AL, Botteri E, Hoff G, Holme Ø, Bretthauer M, Randel KR, Gulichsen EH, El-Safadi B, Barua I, Munck C, Nilsen LR, Svendsen HM, de Lange T (2021)
Women require routine opioids to prevent painful colonoscopies: a randomised controlled trial
Scand J Gastroenterol
DOI 10.1080/00365521.2021.1969683, PubMed 34534048

Schuppan D, Mäki M, Lundin KEA, Isola J, Friesing-Sosnik T, Taavela J, Popp A, Koskenpato J, Langhorst J, Hovde Ø, Lähdeaho ML, Fusco S, Schumann M, Török HP, Kupcinskas J, Zopf Y, Lohse AW, Scheinin M, Kull K, Biedermann L, Byrnes V, Stallmach A, Jahnsen J, Zeitz J, Mohrbacher R et al. (2021)
A Randomized Trial of a Transglutaminase 2 Inhibitor for Celiac Disease
N Engl J Med, 385 (1), 35-45
DOI 10.1056/NEJMoa2032441, PubMed 34192430

Skaarud KJ, Hov JR, Hansen SH, Kummen M, Valeur J, Seljeflot I, Bye A, Paulsen V, Lundin KEA, Troseid M, Tjonnfjord GE, Iversen PO (2021)
Mortality and microbial diversity after allogeneic hematopoietic stem cell transplantation: secondary analysis of a randomized nutritional intervention trial
Sci Rep, 11 (1), 11593
DOI 10.1038/s41598-021-90976-z

Skaarud KJ, Hov JR, Hansen SH, Kummen M, Valeur J, Seljeflot I, Bye A, Paulsen V, Lundin KEA, Trøseid M, Tjønnfjord GE, Iversen PO (2021)
Mortality and microbial diversity after allogeneic hematopoietic stem cell transplantation: secondary analysis of a randomized nutritional intervention trial
Sci Rep, 11 (1), 11593
DOI 10.1038/s41598-021-90976-z, PubMed 34078971

Usher-Smith JA, Mills KM, Riedinger C, Saunders CL, Helsingen LM, Lytvyn L, Buskermolen M, Lansdorp-Vogelaar I, Bretthauer M, Guyatt G, Griffin SJ (2021)
The impact of information about different absolute benefits and harms on intention to participate in colorectal cancer screening: A think-aloud study and online randomised experiment
PLoS One, 16 (2), e0246991
DOI 10.1371/journal.pone.0246991, PubMed 33592037

Vedeld HM, Grimsrud MM, Andresen K, Pharo HD, von Seth E, Karlsen TH, Honne H, Paulsen V, Färkkilä MA, Bergquist A, Jeanmougin M, Aabakken L, Boberg KM, Folseraas T, Lind GE (2021)
Early and accurate detection of cholangiocarcinoma in patients with primary sclerosing cholangitis by methylation markers in bile
Hepatology (in press)
DOI 10.1002/hep.32125, PubMed 34435693

Waldmann E, Kammerlander AA, Gessl I, Penz D, Majcher B, Hinterberger A, Bretthauer M, Trauner MH, Ferlitsch M (2021)
Association of Adenoma Detection Rate and Adenoma Characteristics With Colorectal Cancer Mortality After Screening Colonoscopy
Clin Gastroenterol Hepatol, 19 (9), 1890-1898
DOI 10.1016/j.cgh.2021.04.023, PubMed 33878471

Wieszczy P, Kaminski MF, Løberg M, Bugajski M, Bretthauer M, Kalager M (2021)
Estimation of overdiagnosis in colorectal cancer screening with sigmoidoscopy and faecal occult blood testing: comparison of simulation models
BMJ Open, 11 (4), e042158
DOI 10.1136/bmjopen-2020-042158, PubMed 33853794

 
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