Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2021 from OUS - Department of Research and Development (Div Emerg. & Clin. Care)

33 publications found

Alm-Kruse K, Sørensen G, Osbakk SA, Sunde K, Bendz B, Andersen GØ, Fiane A, Hagen OA, Kramer-Johansen J (2021)
Outcome in refractory out-of-hospital cardiac arrest before and after implementation of an ECPR protocol
Resuscitation, 162, 35-42
DOI 10.1016/j.resuscitation.2021.01.038, PubMed 33581226

Amdal CD, Pe M, Falk RS, Piccinin C, Bottomley A, Arraras JI, Darlington AS, Hofsø K, Holzner B, Jørgensen NMH, Kulis D, Rimehaug SA, Singer S, Taylor K, Wheelwright S, Bjordal K (2021)
Health-related quality of life issues, including symptoms, in patients with active COVID-19 or post COVID-19; a systematic literature review
Qual Life Res
DOI 10.1007/s11136-021-02908-z, PubMed 34146226

Aslam TN, Klitgaard TL, Hofso K, Rasmussen BS, Laake JH (2021)
Spontaneous Versus Controlled Mechanical Ventilation in Patients with Acute Respiratory Distress Syndrome
Curr. Anesthesiol. Rep., 11 (2), 85-91
DOI 10.1007/s40140-021-00443-8

Avidan A, Sprung CL, Schefold JC, Ricou B, Hartog CS, Nates JL, Jaschinski U, Lobo SM, Joynt GM, Lesieur O, Weiss M, Antonelli M, Bülow HH, Bocci MG, Robertsen A, Anstey MH, Estébanez-Montiel B, Lautrette A, Gruber A, Estella A, Mullick S, Sreedharan R, Michalsen A, Feldman C, Tisljar K et al. (2021)
Variations in end-of-life practices in intensive care units worldwide (Ethicus-2): a prospective observational study
Lancet Respir Med, 9 (10), 1101-1110
DOI 10.1016/S2213-2600(21)00261-7, PubMed 34364537

Benterud BP, Lindenskov PHH, Rosseland LA (2021)
No change in plasma potassium concentration during 10 minutes of apnoea: An observational study on potential organ donors
Acta Anaesthesiol Scand, 65 (9), 1300-1304
DOI 10.1111/aas.13940, PubMed 34137462

Bye EK, Bogstrand ST, Rossow I (2021)
The importance of alcohol in elderly's hospital admissions for fall injuries: a population case-control study
Nord. Stud. Alcohol Drugs, 14550725211015836
DOI 10.1177/14550725211015836

Chew MS, Kattainen S, Haase N, Buanes EA, Kristinsdottir LB, Hofsø K, Laake JH, Kvåle R, Hästbacka J, Reinikainen M, Bendel S, Varpula T, Walther S, Perner A, Flaatten HK, Sigurdsson MI (2021)
A descriptive study of the surge response and outcomes of ICU patients with COVID-19 during first wave in Nordic countries
Acta Anaesthesiol Scand
DOI 10.1111/aas.13983, PubMed 34570897

Christensen EE, Jørgensen MJ, Nore KG, Dahl TB, Yang K, Ranheim T, Huse C, Lind A, Nur S, Stiksrud B, Jenum S, Tonby K, Holter JC, Holten AR, Halvorsen B, Dyrhol-Riise AM (2021)
Critical COVID-19 is associated with distinct leukocyte phenotypes and transcriptome patterns
J Intern Med, 290 (3), 677-692
DOI 10.1111/joim.13310, PubMed 34080738

Comelon M, Raeder J, Drægni T, Lieng M, Lenz H (2021)
Tapentadol versus oxycodone analgesia and side effects after laparoscopic hysterectomy: A randomised controlled trial
Eur J Anaesthesiol, 38 (9), 995-1002
DOI 10.1097/EJA.0000000000001425, PubMed 33428347

Dahl HM, Andelic N, Løvstad M, Holthe IL, Hestnes M, Diseth TH, Myhre MC (2021)
Epidemiology of traumatic brain injury in children 15 years and younger in South-Eastern Norway in 2015-16. Implications for prevention and follow-up needs
Eur J Paediatr Neurol, 31, 70-77
DOI 10.1016/j.ejpn.2021.02.002, PubMed 33647532

Dokken M, Rustøen T, Diep LM, Fagermoen FE, Huse RI, A Rosland G, Egerod I, Bentsen GK (2021)
Iatrogenic withdrawal syndrome frequently occurs in paediatric intensive care without algorithm for tapering of analgosedation
Acta Anaesthesiol Scand, 65 (7), 928-935
DOI 10.1111/aas.13818, PubMed 33728643

Finstad J, Røise O, Rosseland LA, Clausen T, Havnes IA (2021)
Discharge from the trauma centre: exposure to opioids, unmet information needs and lack of follow up-a qualitative study among physical trauma survivors
Scand J Trauma Resusc Emerg Med, 29 (1), 121
DOI 10.1186/s13049-021-00938-7, PubMed 34419130

Frivold G, Ågård AS, Jensen HI, Åkerman E, Fossum M, Alfheim HB, Rasi M, Lind R (2021)
Family involvement in the intensive care unit in four Nordic countries
Nurs Crit Care
DOI 10.1111/nicc.12702, PubMed 34405494

Haidl F, Tronstad C, Rosseland LA, Dahl V (2021)
Maternal haemodynamics during labour epidural analgesia with and without adrenaline
Scand J Pain, 21 (4), 680-687
DOI 10.1515/sjpain-2020-0176, PubMed 33964196

Holm S, Kared H, Michelsen AE, Kong XY, Dahl TB, Schultz NH, Nyman TA, Fladeby C, Seljeflot I, Ueland T, Stensland M, Mjaaland S, Goll GL, Nissen-Meyer LS, Aukrust P, Skagen K, Gregersen I, Skjelland M, Holme PA, Munthe LA, Halvorsen B (2021)
Immune complexes, innate immunity, and NETosis in ChAdOx1 vaccine-induced thrombocytopenia
Eur Heart J, 42 (39), 4064-4072
DOI 10.1093/eurheartj/ehab506, PubMed 34405870

Karlsen TR, Kong XY, Holm S, Quiles-Jiménez A, Dahl TB, Yang K, Sagen EL, Skarpengland T, S Øgaard JD, Holm K, Vestad B, Olsen MB, Aukrust P, Bjørås M, Hov JR, Halvorsen B, Gregersen I (2021)
NEIL3-deficiency increases gut permeability and contributes to a pro-atherogenic metabolic phenotype
Sci Rep, 11 (1), 19749
DOI 10.1038/s41598-021-98820-0, PubMed 34611194

Laake JH, Buanes EA, Småstuen MC, Kvåle R, Olsen BF, Rustøen T, Strand K, Sørensen V, Hofsø K (2021)
Characteristics, management and survival of ICU patients with coronavirus disease-19 in Norway, March-June 2020. A prospective observational study
Acta Anaesthesiol Scand, 65 (5), 618-628
DOI 10.1111/aas.13785, PubMed 33501998

Lenz H, Hoiseth LO, Comelon M, Draegni T, Rosseland LA (2021)
Determination of equi-analgesic doses of inhaled methoxyflurane versus intravenous fentanyl using the cold pressor test in volunteers: a randomised, double-blinded, placebo-controlled crossover study
Br. J. Anaesth., 126 (5), 1038-1045
DOI 10.1016/j.bja.2020.12.045

Li Y, Khanal P, Norheim F, Hjorth M, Bjellaas T, Drevon CA, Vaage J, Kimmel AR, Dalen KT (2021)
Plin2 deletion increases cholesteryl ester lipid droplet content and disturbs cholesterol balance in adrenal cortex
J Lipid Res, 62, 100048
DOI 10.1016/j.jlr.2021.100048, PubMed 33582145

Lie I, Stafseth S, Skogstad L, Hovland IS, Hovde H, Ekeberg Ø, Ræder J (2021)
Healthcare professionals in COVID-19-intensive care units in Norway: preparedness and working conditions: a cohort study
BMJ Open, 11 (10), e049135
DOI 10.1136/bmjopen-2021-049135, PubMed 34635518

Liu FC, Grimsrud TK, Veierod MB, Robsahm TE, Ghiasvand R, Babigumira R, Shala NK, Stenehjem JS (2021)
Ultraviolet radiation and risk of cutaneous melanoma and squamous cell carcinoma in males and females in the Norwegian Offshore Petroleum Workers cohort
Am. J. Ind. Med., 64 (6), 496-510
DOI 10.1002/ajim.23240

Michelsen TM, Tronstad C, Rosseland LA (2021)
Blood pressure and cardiac output during caesarean delivery under spinal anaesthesia: a prospective cohort study
BMJ Open, 11 (6), e046102
DOI 10.1136/bmjopen-2020-046102, PubMed 34127491

Petosic A, Småstuen MC, Beeckman D, Flaatten H, Sunde K, Wøien H (2021)
Multifaceted intervention including Facebook-groups to improve guideline-adherence in ICU: A quasi-experimental interrupted time series study
Acta Anaesthesiol Scand
DOI 10.1111/aas.13969, PubMed 34368947

Reine E, Aase K, Raeder J, Thorud A, Aarsnes RM, Rustøen T (2021)
Exploring postoperative handover quality in relation to patient condition: A mixed methods study
J Clin Nurs, 30 (7-8), 1046-1059
DOI 10.1111/jocn.15650, PubMed 33434381

Robertsen A, Helseth E, Førde R (2021)
Inter-physician variability in strategies linked to treatment limitations after severe traumatic brain injury; proactivity or wait-and-see
BMC Med Ethics, 22 (1), 43
DOI 10.1186/s12910-021-00612-8, PubMed 33849500

Sahakyan MA, Verbeke CS, Tholfsen T, Ignjatovic D, Kleive D, Buanes T, Lassen K, Røsok BI, Labori KJ, Edwin B (2021)
Prognostic Impact of Resection Margin Status in Distal Pancreatectomy for Ductal Adenocarcinoma
Ann Surg Oncol
DOI 10.1245/s10434-021-10464-6, PubMed 34296358

Stenehjem JS, Babigumira R, Hosgood HD, Veierød MB, Samuelsen SO, Bråtveit M, Kirkeleit J, Rothman N, Lan Q, Silverman DT, Friesen MC, Robsahm TE, Kjærheim K, Andreassen BK, Shala NK, Liu FC, Strand LÅ, Grimsrud TK (2021)
Cohort Profile: Norwegian Offshore Petroleum Workers (NOPW) Cohort
Int J Epidemiol, 50 (2), 398-399
DOI 10.1093/ije/dyaa107, PubMed 32879941

Stenehjem JS, Røise O, Nordseth T, Clausen T, Natvig B, O Skurtveit S, Eken T, Kristiansen T, Gran JM, Rosseland LA (2021)
Injury Prevention and long-term Outcomes following Trauma-the IPOT project: a protocol for prospective nationwide registry-based studies in Norway
BMJ Open, 11 (5), e046954
DOI 10.1136/bmjopen-2020-046954, PubMed 34006552

Torp HA, Skurtveit S, Skaga NO, Gustavsen I, Gran JM, Rosseland LA (2021)
Pre-injury dispensing of psychoactive prescription drugs in a ten years trauma population: a retrospective registry analysis
Scand J Trauma Resusc Emerg Med, 29 (1), 125
DOI 10.1186/s13049-021-00939-6, PubMed 34454541

Ueland T, Abraityte A, Norum H, Varathalingam S, Gullestad L, Aukrust P, Andreassen AK (2021)
Circulating regulators of the wingless pathway in precapillary pulmonary hypertension
Respirology, 26 (6), 574-581
DOI 10.1111/resp.14048, PubMed 33830565

Valeberg BT, Dihle A, Småstuen MC, Endresen AO, Rustøen T (2021)
The effects of a psycho-educational intervention to improve pain management after day surgery: A randomised clinical trial
J Clin Nurs, 30 (7-8), 1132-1143
DOI 10.1111/jocn.15659, PubMed 33432643

Valsø Å, Rustøen T, Småstuen MC, Puntillo K, Skogstad L, Schou-Bredal I, Sunde K, Tøien K (2021)
Occurrence and characteristics of pain after ICU discharge: A longitudinal study
Nurs Crit Care
DOI 10.1111/nicc.12701, PubMed 34382725

Wimmer H, Lundqvist C, Šaltytė Benth J, Stavem K, Andersen GØ, Henriksen J, Drægni T, Sunde K, Nakstad ER (2021)
Health-related quality of life after out-of-hospital cardiac arrest - a five-year follow-up studyJūratė Šaltytė Benth
Resuscitation, 162, 372-380
DOI 10.1016/j.resuscitation.2021.01.036, PubMed 33571604

 
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