Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2021 from OUS - Department of Transplantation Medicine

45 publications found

Antonelli G, Karsensten JG, Bhat P, Ijoma U, Osuagwu C, Desalegn H, Abera H, Guy C, Vilmann P, Dinis-Ribeiro M, Ponchon T, Sabbagh LC, Pausawasdi N, Makharia G, Hassan C, Veitch A, Aabakken L, Ebigbo A, Endoscopy and COVID-19 Cascade Working Group, European Society of Gastrointestinal Endoscopy, World Endoscopy Organization and World Gastroenterology Organization (2021)
Resuming endoscopy during COVID-19 pandemic: ESGE, WEO and WGO Joint Cascade Guideline for Resource Limited Settings
Endosc Int Open, 9 (4), E543-E551
DOI 10.1055/a-1400-9135, PubMed 33816775

Åvitsland TL, Aabakken L (2021)
Endoscopic retrograde cholangiopancreatography in infants and children
Endosc Int Open, 9 (3), E292-E296
DOI 10.1055/a-1337-2212, PubMed 33655024

Bakker OB, Ramírez-Sánchez AD, Borek ZA, de Klein N, Li Y, Modderman R, Kooy-Winkelaar Y, Johannesen MK, Matarese F, Martens JHA, Kumar V, van Bergen J, Qiao SW, Lundin KEA, Sollid LM, Koning F, Wijmenga C, Withoff S, Jonkers IH (2021)
Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells
Sci Rep, 11 (1), 9252
DOI 10.1038/s41598-021-86612-5, PubMed 33927210

Bekkelund M, Sangnes DA, Søfteland E, Aabakken L, Biermann M, Steinsvik EK, Hausken T, Dimcevski G, Hatlebakk JG (2021)
Gastroparesis Symptoms Associated with Intestinal Hypomotility: An Explorative Study Using Wireless Motility Capsule
Clin Exp Gastroenterol, 14, 133-144
DOI 10.2147/CEG.S304854, PubMed 33953592

Bjørkto MH, Barratt-Due A, Nordøy I, Dörje C, Galteland E, Lind A, Hilli A, Aukrust P, Mjøen G (2021)
The use of eculizumab in Capnocytophaga canimorsus associated thrombotic microangiopathy: a case report
BMC Infect Dis, 21 (1), 137
DOI 10.1186/s12879-021-05789-2, PubMed 33526010

Borge CR, Larsen MH, Osborne RH, Engebretsen E, Andersen MH, Holter IA, Leine M, Wahl AK (2021)
Exploring patients' and health professionals' perspectives on health literacy needs in the context of chronic obstructive pulmonary disease
Chronic Illn., 1742395321999441

Bossen L, Vesterhus M, Hov JR, Färkkilä M, Rosenberg WM, Møller HJ, Boberg KM, Karlsen TH, Grønbæk H (2021)
Circulating Macrophage Activation Markers Predict Transplant-Free Survival in Patients With Primary Sclerosing Cholangitis
Clin Transl Gastroenterol, 12 (3), e00315
DOI 10.14309/ctg.0000000000000315, PubMed 33646203

Brennvall HM, Bjune T, Sverdrup Ø, Ráki M, Abedini S (2021)
Glomerulonefritt etter kontakt med hest
Tidsskr Nor Laegeforen, 141 (4)
DOI 10.4045/tidsskr.20.0780, PubMed 33685097

Dahal-Koirala S, Risnes LF, Neumann RS, Christophersen A, Lundin KEA, Sandve GK, Qiao SW, Sollid LM (2021)
Comprehensive Analysis of CDR3 Sequences in Gluten-Specific T-Cell Receptors Reveals a Dominant R-Motif and Several New Minor Motifs
Front Immunol, 12, 639672
DOI 10.3389/fimmu.2021.639672, PubMed 33927715

Dahl KG, Wahl AK, Urstad KH, Falk RS, Andersen MH (2021)
Changes in Health Literacy during the first year following a kidney transplantation: Using the Health Literacy Questionnaire
Patient Educ Couns (in press)
DOI 10.1016/j.pec.2020.12.028, PubMed 33454146

Dahle DO, Skauby M, Langberg CW, Brabrand K, Wessel N, Midtvedt K (2021)
Renal Cell Carcinoma and Kidney Transplantation: A Narrative Review
Transplantation (in press)
DOI 10.1097/TP.0000000000003762, PubMed 33741842

Degenhardt F, Mayr G, Wendorff M, Boucher G, Ellinghaus E, Ellinghaus D, ElAbd H, Rosati E, Hübenthal M, Juzenas S, Abedian S, Vahedi H, Thelma BK, Yang SK, Ye BD, Cheon JH, Datta LW, Daryani NE, Ellul P, Esaki M, Fuyuno Y, McGovern DPB, Haritunians T, Hong M, Juyal G et al. (2021)
Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations
Hum Mol Genet, 30 (5), 356-369
DOI 10.1093/hmg/ddab017, PubMed 33555323

Dhillon AK, Rupp C, Bergquist A, Voitl R, Folseraas T, Trøseid M, Midttun Ø, Ueland PM, Karlsen TH, Vesterhus M, Kummen M, Hov JR (2021)
Associations of neopterin and kynurenine-tryptophan ratio with survival in primary sclerosing cholangitis
Scand J Gastroenterol, 56 (4), 443-452
DOI 10.1080/00365521.2021.1880627, PubMed 33583308

Dueland S, Yaqub S, Syversveen T, Carling U, Hagness M, Brudvik KW, Line PD (2021)
Survival Outcomes After Portal Vein Embolization and Liver Resection Compared With Liver Transplant for Patients With Extensive Colorectal Cancer Liver Metastases
JAMA Surg
DOI 10.1001/jamasurg.2021.0267, PubMed 33787838

Gatti F, Mia S, Hammarström C, Frerker N, Fosby B, Wang J, Pietka W, Sundnes O, Hol J, Kasprzycka M, Haraldsen G (2021)
Nuclear IL-33 restrains the early conversion of fibroblasts to an extracellular matrix-secreting phenotype
Sci Rep, 11 (1), 108
DOI 10.1038/s41598-020-80509-5, PubMed 33420328

Ghila L, Legøy TA, Mathisen AF, Abadpour S, Paulo JA, Scholz H, Ræder H, Chera S (2021)
Chronically Elevated Exogenous Glucose Elicits Antipodal Effects on the Proteome Signature of Differentiating Human iPSC-Derived Pancreatic Progenitors
Int J Mol Sci, 22 (7)
DOI 10.3390/ijms22073698, PubMed 33918250

Gulseth E, Urdal A, Andersen MH, Diseth T, Aksnes G, Emblem R, Wæhre A (2021)
High satisfaction on genital self-perception and sexual function in healthy Norwegian male adolescents
J Pediatr Urol (in press)
DOI 10.1016/j.jpurol.2021.02.015, PubMed 33750647

Haugen AJ, Hallan S, Langberg NE, Dahle DO, Pihlstrøm H, Birkeland KI, Reisæter AV, Midtvedt K, Hartmann A, Holdaas H, Mjøen G (2021)
Increased risk of ischemic heart disease after kidney donation
Nephrol Dial Transplant (in press)
DOI 10.1093/ndt/gfab054, PubMed 33624826

Haugen AJ, Mjøen G (2021)
Living donation - any news on the donor?
Curr Opin Organ Transplant, 26 (1), 85-90
DOI 10.1097/MOT.0000000000000830, PubMed 33278148

Hausken J, Haugaa H, Hagness M, Line PD, Melum E, Tønnessen TI (2021)
Thoracic Epidural Analgesia for Postoperative Pain Management in Liver Transplantation: A 10-year Study on 685 Liver Transplant Recipients
Transplant Direct, 7 (2), e648
DOI 10.1097/TXD.0000000000001101, PubMed 33437863

Helve J, Kramer A, Abad Diez JM, Aresté-Fosalba N, Arici M, Cases A, Collart F, Heaf J, De Meester J, Nordio M, Palsson R, Pobes A, Rydell H, Reisæter AV, Massy ZA, Jager KJ, Finne P (2021)
Effect of comorbidities on survival in patients >80 years of age at onset of renal replacement therapy: data from the ERA-EDTA Registry
Nephrol Dial Transplant, 36 (4), 688-694
DOI 10.1093/ndt/gfaa278, PubMed 33537775

Hoff G, Botteri E, Huppertz-Hauss G, Kvamme JM, Holme Ø, Aabakken L, Dahler S, Medhus AW, Blomgren I, Sandvei P, Darre-Næss O, Kjellevold Ø, Seip B (2021)
The effect of train-the-colonoscopy-trainer course on colonoscopy quality indicators
Endoscopy
DOI 10.1055/a-1352-4583, PubMed 33622001

Hugenschmidt H, Labori KJ, Borgen E, Brunborg C, Schirmer CB, Seeberg LT, Naume B, Wiedswang G (2021)
Preoperative CTC-Detection by CellSearch® Is Associated with Early Distant Metastasis and Impaired Survival in Resected Pancreatic Cancer
Cancers (Basel), 13 (3)
DOI 10.3390/cancers13030485, PubMed 33513877

Jenssen T, Kristensen B, Uglenes I, Larsen LS, Allgot B (2021)
Primary healthcare teams with a diabetes nurse is a solution
Tidsskr Nor Laegeforen, 141 (5)
DOI 10.4045/tidsskr.20.0999, PubMed 33754683

Jiang X, Bergquist A, Löscher BS, Venkatesh G, Mold JE, Holm K, Laerdahl JK, Skånland SS, Maleki KT, Cornillet M, Taskén K, Franke A, Karlsen TH, Björkström NK, Melum E (2021)
A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
Sci Transl Med, 13 (582)
DOI 10.1126/scitranslmed.abb0036, PubMed 33627483

Kindem IA, Bjerre A, Åsberg MScPharm A, Midtvedt K, Bergan MScPharm S, Vethe MScPharm NT (2021)
Tacrolimus measured in capillary volumetric microsamples in pediatric patients-a cross-validation study
Ther Drug Monit (in press)
DOI 10.1097/FTD.0000000000000873, PubMed 33596033

Kjosen G, Rydenfelt K, Horneland R, Aandahl EM, Line PD, Dorenberg E, Berstad AE, Brabrand K, Hagen G, Pischke SE, Bergmann GB, Nordheim E, Jenssen TG, Tonnessen TI, Haugaa H (2021)
Early detection of complications in pancreas transplants by microdialysis catheters, an observational feasibility study
PLoS One, 16 (3), e0247615

Lindeman I, Zhou C, Eggesbø LM, Miao Z, Polak J, Lundin KEA, Jahnsen J, Qiao SW, Iversen R, Sollid LM (2021)
Longevity, clonal relationship, and transcriptional program of celiac disease-specific plasma cells
J Exp Med, 218 (2)
DOI 10.1084/jem.20200852, PubMed 33095260

Lissing M, Nowak G, Adam R, Karam V, Boyd A, Gouya L, Meersseman W, Melum E, Ołdakowska-Jedynak U, Reiter FP, Colmenero J, Sanchez R, Herden U, Langendonk J, Ventura P, Isoniemi H, Boillot O, Braun F, Perrodin S, Mowlem E, Wahlin S, European Liver and Intestine Transplant Association (2021)
Liver Transplantation for Acute Intermittent Porphyria
Liver Transpl, 27 (4), 491-501
DOI 10.1002/lt.25959, PubMed 33259654

Mjøen G, Maggiore U, Kessaris N, Kimenai D, Watschinger B, Mariat C, Sever MS, Crespo M, Peruzzi L, Spasovski G, Sørensen SS, Heemann U, Pascual J, Viklicky O, Courtney AE, Hadaya K, Wagner L, Nistor I, Hadjianastassiou V, Durlik M, Helanterä I, Oberbauer R, Oniscu G, Hilbrands L, Abramowicz D et al. (2021)
Long-term risks after kidney donation: How do we inform potential donors? A survey from descartes and EKITA transplantation working groups
Nephrol Dial Transplant (in press)
DOI 10.1093/ndt/gfab035, PubMed 33585931

Mori Y, Neumann H, Misawa M, Kudo SE, Bretthauer M (2021)
Artificial intelligence in colonoscopy - Now on the market. What's next?
J Gastroenterol Hepatol, 36 (1), 7-11
DOI 10.1111/jgh.15339, PubMed 33179322

Myhrstad MCW, Slydahl M, Hellmann M, Garnweidner-Holme L, Lundin KEA, Henriksen C, Telle-Hansen VH (2021)
Nutritional quality and costs of gluten-free products: a case-control study of food products on the Norwegian marked
Food Nutr Res, 65
DOI 10.29219/fnr.v65.6121, PubMed 33841066

Nordheim E, Geir Jenssen T (2021)
Chronic kidney disease in patients with diabetes mellitus
Endocr Connect, 10 (5), R151-R159
DOI 10.1530/EC-21-0097, PubMed 33830068

Nordheim E, Lindahl JP, Carlsen RK, Åsberg A, Birkeland KI, Horneland R, Boye B, Scholz H, Jenssen TG (2021)
Patient selection for islet or solid organ pancreas transplantation: experiences from a multidisciplinary outpatient-clinic approach
Endocr Connect, 10 (2), 230-239
DOI 10.1530/EC-20-0519, PubMed 33544090

Onsøien MO, Midtvedt K, Reisæter AV, Aasarød K, Waldum-Grevbo B, Vikse BE, Eriksen BO, Åsberg A (2021)
Blood Pressure Treatment in Kidney Transplant Recipients-Can We Improve?
Transplant Direct, 7 (4), e688
DOI 10.1097/TXD.0000000000001142, PubMed 33786373

Pagano E, Elias JE, Schneditz G, Saveljeva S, Holland LM, Borrelli F, Karlsen TH, Kaser A, Kaneider NC (2021)
Activation of the GPR35 pathway drives angiogenesis in the tumour microenvironment
Gut (in press)
DOI 10.1136/gutjnl-2020-323363, PubMed 33758004

Pippias M, Stel VS, Arnol M, Bemelman F, Berger SP, Ponikvar JB, Kramar R, Magaz Á, Nordio M, Peters-Sengers H, Reisæter AV, Sørensen SS, Massy ZA, Jager KJ (2021)
Temporal Trends in the Quality of Deceased Donor Kidneys and Kidney Transplant Outcomes in Europe: an analysis by the ERA-EDTA Registry
Nephrol Dial Transplant (in press)
DOI 10.1093/ndt/gfab156, PubMed 33848355

Reich M, Spomer L, Klindt C, Fuchs K, Stindt J, Deutschmann K, Höhne J, Liaskou E, Hov JR, Karlsen TH, Beuers U, Verheij J, Ferreira-Gonzalez S, Hirschfield G, Forbes SJ, Schramm C, Esposito I, Nierhoff D, Fickert P, Fuchs CD, Trauner M, García-Beccaria M, Gabernet G, Nahnsen S, Mallm JP et al. (2021)
Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis
J Hepatol (in press)
DOI 10.1016/j.jhep.2021.03.029, PubMed 33872692

Sampaziotis F, Muraro D, Tysoe OC, Sawiak S, Beach TE, Godfrey EM, Upponi SS, Brevini T, Wesley BT, Garcia-Bernardo J, Mahbubani K, Canu G, Gieseck R, Berntsen NL, Mulcahy VL, Crick K, Fear C, Robinson S, Swift L, Gambardella L, Bargehr J, Ortmann D, Brown SE, Osnato A, Murphy MP et al. (2021)
Cholangiocyte organoids can repair bile ducts after transplantation in the human liver
Science, 371 (6531), 839-846
DOI 10.1126/science.aaz6964, PubMed 33602855

Sollid LM, Lundin KEA, Leivestad T, Spurkland A, Vartdal F (2021)
Erik Thorsby (1938-2021)
Immunogenetics (in press)
DOI 10.1007/s00251-021-01218-5, PubMed 33956175

Usher-Smith JA, Mills KM, Riedinger C, Saunders CL, Helsingen LM, Lytvyn L, Buskermolen M, Lansdorp-Vogelaar I, Bretthauer M, Guyatt G, Griffin SJ (2021)
The impact of information about different absolute benefits and harms on intention to participate in colorectal cancer screening: A think-aloud study and online randomised experiment
PLoS One, 16 (2), e0246991
DOI 10.1371/journal.pone.0246991, PubMed 33592037

Wahl AK, Osborne RH, Larsen MH, Andersen MH, Holter IA, Borge CR (2021)
Exploring health literacy needs in Chronic obstructive pulmonary disease (COPD): Associations between demographic, clinical variables, psychological well-being and health literacy
Heart Lung, 50 (3), 417-424
DOI 10.1016/j.hrtlng.2021.02.007, PubMed 33618148

Waldmann EA, Kammerlander AA, Gessl I, Penz D, Majcher B, Hinterberger A, Bretthauer M, Trauner MH, Ferlitsch M (2021)
Association of Adenoma Detection Rate and Adenoma Characteristics with Colorectal Cancer Mortality after screening colonoscopy
Clin Gastroenterol Hepatol (in press)
DOI 10.1016/j.cgh.2021.04.023, PubMed 33878471

Wieszczy P, Kaminski MF, Løberg M, Bugajski M, Bretthauer M, Kalager M (2021)
Estimation of overdiagnosis in colorectal cancer screening with sigmoidoscopy and faecal occult blood testing: comparison of simulation models
BMJ Open, 11 (4), e042158
DOI 10.1136/bmjopen-2020-042158, PubMed 33853794

Zhou AX, Mondal T, Tabish AM, Abadpour S, Ericson E, Smith DM, Knöll R, Scholz H, Kanduri C, Tyrberg B, Althage M (2021)
The long noncoding RNA TUNAR modulates Wnt signaling and regulates human β-cell proliferation
Am J Physiol Endocrinol Metab, 320 (4), E846-E857
DOI 10.1152/ajpendo.00335.2020, PubMed 33682459

 
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