Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2021 from OUS - Department of Gastrointestinal and Paediatric Surgery

27 publications found

Aghayan DL, Kazaryan AM, Fretland ÅA, Røsok B, Barkhatov L, Lassen K, Edwin B (2021)
Evolution of laparoscopic liver surgery: 20-year experience of a Norwegian high-volume referral center
Surg Endosc
DOI 10.1007/s00464-021-08570-3, PubMed 34036419

Alavi DH, Henriksen HB, Lauritzen PM, Kværner AS, Sakinis T, Langleite TM, Henriksen C, Bøhn SK, Paur I, Wiedswang G, Smeland S, Blomhoff R (2021)
Quantification of adipose tissues by Dual-Energy X-Ray Absorptiometry and Computed Tomography in colorectal cancer patients
Clin Nutr ESPEN, 43, 360-368
DOI 10.1016/j.clnesp.2021.03.022, PubMed 34024541

Amrutkar M, Gladhaug IP (2021)
Stellate Cells Aid Growth-Permissive Metabolic Reprogramming and Promote Gemcitabine Chemoresistance in Pancreatic Cancer
Cancers (Basel), 13 (4)
DOI 10.3390/cancers13040601, PubMed 33546284

Andersen BT, Stimec BV, Edwin B, Kazaryan AM, Maziarz PJ, Ignjatovic D (2021)
Re-interpreting mesenteric vascular anatomy on 3D virtual and/or physical models: positioning the middle colic artery bifurcation and its relevance to surgeons operating colon cancer
Surg Endosc
DOI 10.1007/s00464-020-08242-8, PubMed 33492511

Azhar N, Johanssen A, Sundström T, Folkesson J, Wallon C, Kørner H, Blecic L, Forsmo HM, Øresland T, Yaqub S, Buchwald P, Schultz JK, SCANDIV Study Group (2021)
Laparoscopic Lavage vs Primary Resection for Acute Perforated Diverticulitis: Long-term Outcomes From the Scandinavian Diverticulitis (SCANDIV) Randomized Clinical Trial
JAMA Surg, 156 (2), 121-127
DOI 10.1001/jamasurg.2020.5618, PubMed 33355658

Berg KCG, Brunsell TH, Sveen A, Alagaratnam S, Bjørnslett M, Hektoen M, Brudvik KW, Røsok BI, Bjørnbeth BA, Nesbakken A, Lothe RA (2021)
Genomic and prognostic heterogeneity among RAS/BRAFV600E /TP53 co-mutated resectable colorectal liver metastases
Mol Oncol, 15 (4), 830-845
DOI 10.1002/1878-0261.12885, PubMed 33325154

Dueland S, Yaqub S, Syversveen T, Carling U, Hagness M, Brudvik KW, Line PD (2021)
Survival Outcomes After Portal Vein Embolization and Liver Resection Compared With Liver Transplant for Patients With Extensive Colorectal Cancer Liver Metastases
JAMA Surg, 156 (6), 550-557
DOI 10.1001/jamasurg.2021.0267, PubMed 33787838

Fleten KG, Eksteen JJ, Mauseth B, Camilio KA, Vasskog T, Sveinbjørnsson B, Rekdal Ø, Mælandsmo GM, Flatmark K (2021)
Oncolytic peptides DTT-205 and DTT-304 induce complete regression and protective immune response in experimental murine colorectal cancer
Sci Rep, 11 (1), 6731
DOI 10.1038/s41598-021-86239-6, PubMed 33762676

Görgec B, Benedetti Cacciaguerra A, Lanari J, Russolillo N, Cipriani F, Aghayan D, Zimmitti G, Efanov M, Alseidi A, Mocchegiani F, Giuliante F, Ruzzenente A, Rotellar F, Fuks D, D'Hondt M, Vivarelli M, Edwin B, Aldrighetti LA, Ferrero A, Cillo U, Besselink MG, Abu Hilal M (2021)
Assessment of Textbook Outcome in Laparoscopic and Open Liver Surgery
JAMA Surg
DOI 10.1001/jamasurg.2021.2064, PubMed 34076671

Gulseth E, Urdal A, Andersen MH, Diseth T, Aksnes G, Emblem R, Wæhre A (2021)
High satisfaction on genital self-perception and sexual function in healthy Norwegian male adolescents
J Pediatr Urol (in press)
DOI 10.1016/j.jpurol.2021.02.015, PubMed 33750647

Hamre H, Lassen K (2021)
Better overview of pancreatic cancer in Norway
Tidsskr Nor Laegeforen, 141 (1)
DOI 10.4045/tidsskr.20.0869, PubMed 33433104

Hasselgren K, Røsok BI, Larsen PN, Sparrelid E, Lindell G, Schultz NA, Bjørnbeth BA, Isaksson B, Larsson AL, Rizell M, Björnsson B, Sandström P (2021)
ALPPS Improves Survival Compared With TSH in Patients Affected of CRLM: Survival Analysis From the Randomized Controlled Trial LIGRO
Ann Surg, 273 (3), 442-448
DOI 10.1097/SLA.0000000000003701, PubMed 32049675

Hølmebakk T, Wiedswang AM, Meza-Zepeda LA, Hompland I, Lobmaier IVK, Berner JM, Stoldt S, Boye K (2021)
Integrating Anatomical, Molecular and Clinical Risk Factors in Gastrointestinal Stromal Tumor of the Stomach
Ann Surg Oncol
DOI 10.1245/s10434-021-09605-8, PubMed 33651216

Hugenschmidt H, Labori KJ, Borgen E, Brunborg C, Schirmer CB, Seeberg LT, Naume B, Wiedswang G (2021)
Preoperative CTC-Detection by CellSearch® Is Associated with Early Distant Metastasis and Impaired Survival in Resected Pancreatic Cancer
Cancers (Basel), 13 (3)
DOI 10.3390/cancers13030485, PubMed 33513877

Kleive D, Aas E, Angelsen JH, Bringeland EA, Nesbakken A, Nymo LS, Schultz JK, Søreide K, Yaqub S (2021)
Simultaneous Resection of Primary Colorectal Cancer and Synchronous Liver Metastases: Contemporary Practice, Evidence and Knowledge Gaps
Oncol Ther, 9 (1), 111-120
DOI 10.1007/s40487-021-00148-2, PubMed 33759076

Lund-Andersen C, Torgunrud A, Fleten KG, Flatmark K (2021)
Omics analyses in peritoneal metastasis-utility in the management of peritoneal metastases from colorectal cancer and pseudomyxoma peritonei: a narrative review
J Gastrointest Oncol, 12 (Suppl 1), S191-S203
DOI 10.21037/jgo-20-136, PubMed 33968437

Mahawar KK, Omar I, Singhal R, Aggarwal S, Allouch MI, Alsabah SK, Angrisani L, Badiuddin FM, Balibrea JM, Bashir A, Behrens E, Bhatia K, Biertho L, Biter LU, Dargent J, De Luca M, DeMaria E, Elfawal MH, Fried M, Gawdat KA, Graham Y, Herrera MF, Himpens JM, Hussain FA, Kasama K et al. (2021)
The first modified Delphi consensus statement on sleeve gastrectomy
Surg Endosc
DOI 10.1007/s00464-020-08216-w, PubMed 33433676

Mala T (2021)
Finding the sweet spot in the surgical treatment of diabetes in obesity
Br J Surg (in press)
DOI 10.1093/bjs/znab179, PubMed 33914072

Mariathasan AB, Boye K, Dueland S, Flatmark K, Larsen SG (2021)
Metastases in locally advanced rectal cancer undergoing curatively intended treatment
Eur J Surg Oncol (in press)
DOI 10.1016/j.ejso.2021.04.023, PubMed 34049768

Meltzer S, Torgunrud A, Abrahamsson H, Solbakken AM, Flatmark K, Dueland S, Bakke KM, Bousquet PA, Negård A, Johansen C, Lyckander LG, Larsen FO, Schou JV, Redalen KR, Ree AH (2021)
The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer
Br J Cancer
DOI 10.1038/s41416-021-01377-y, PubMed 33837301

Sahakyan MA, Røsok BI, Tholfsen T, Kleive D, Waage A, Ignjatovic D, Buanes T, Labori KJ, Edwin B (2021)
Implementation and training with laparoscopic distal pancreatectomy: 23-year experience from a high-volume center
Surg Endosc
DOI 10.1007/s00464-021-08306-3, PubMed 33534075

Sántha P, Lenggenhager D, Finstadsveen A, Dorg L, Tøndel K, Amrutkar M, Gladhaug IP, Verbeke C (2021)
Morphological Heterogeneity in Pancreatic Cancer Reflects Structural and Functional Divergence
Cancers (Basel), 13 (4)
DOI 10.3390/cancers13040895, PubMed 33672734

Slørdahl KS, Klotz D, Olsen JÅ, Skovlund E, Undseth C, Abildgaard HL, Brændengen M, Nesbakken A, Larsen SG, Hanekamp BA, Holmboe L, Tvedt R, Sveen A, Lothe RA, Malinen E, Kaasa S, Guren MG (2021)
Treatment outcomes and prognostic factors after chemoradiotherapy for anal cancer
Acta Oncol
DOI 10.1080/0284186X.2021.1918763, PubMed 33966592

Soreide K, Yaqub S, Hallet J, Kvaløy JT, Kleppe TS (2021)
A Risk Model of Admitting Patients With Silent SARS-CoV-2 Infection to Surgery and Development of Severe Postoperative Outcomes and Death: Projections Over 24 Months for 5 Geographical Regions
Ann Surg, 273 (2), 208-216
DOI 10.1097/SLA.0000000000004583, PubMed 33156071

Sparrelid E, Hasselgren K, Røsok BI, Larsen PN, Schultz NA, Carling U, Fallentin E, Gilg S, Sandström P, Lindell G, Björnsson B (2021)
How should liver hypertrophy be stimulated? A comparison of upfront associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) and portal vein embolization (PVE) with rescue possibility
Hepatobiliary Surg Nutr, 10 (1), 1-8
DOI 10.21037/hbsn.2019.10.36, PubMed 33575285

Thorgersen EB, Asvall J, Frøysnes IS, Schjalm C, Larsen SG, Dueland S, Andersson Y, Fodstad Ø, Mollnes TE, Flatmark K (2021)
Increased Local Inflammatory Response to MOC31PE Immunotoxin After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
Ann Surg Oncol
DOI 10.1245/s10434-021-10022-0, PubMed 34019185

Yaqub S, Rana MU (2021)
Vaccination does not break fasting during Ramadan
Tidsskr Nor Laegeforen, 141 (7)
DOI 10.4045/tidsskr.21.0302, PubMed 33950656

 
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