Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2020 from OUS - Department of Haematology
56 publications found
Utility of coagulation analyses to assess thromboprophylaxis with dalteparin in intensive care unit patients
Acta Anaesthesiol Scand
DOI 10.1111/aas.13748, PubMed 33205407
Indirect regulation of TFPI-2 expression by miR-494 in breast cancer cells
Sci Rep, 10 (1), 4036
DOI 10.1038/s41598-020-61018-x, PubMed 32132611
The association of urine markers of iodine intake with development and growth among children in rural Uganda: a secondary analysis of a randomised education trial
Public Health Nutr, 1-10 (in press)
DOI 10.1017/S1368980020001603, PubMed 32654677
Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with FLT3-internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
Haematologica, 105 (6), 1507-1516
DOI 10.3324/haematol.2019.243410, PubMed 32241850
Cold agglutinin disease revisited: a multinational, observational study of 232 patients
Blood, 136 (4), 480-488
DOI 10.1182/blood.2020005674, PubMed 32374875
Cold agglutinin disease: where do we stand, and where are we going?
Clin Adv Hematol Oncol, 18 (1), 35-44
PubMed 32511221
Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation
iScience, 23 (6), 101154
DOI 10.1016/j.isci.2020.101154, PubMed 32450518
DNMT3B deficiency alters mitochondrial biogenesis and α-ketoglutarate levels in human embryonic stem cells
Stem Cells, 38 (11), 1409-1422
DOI 10.1002/stem.3256, PubMed 32652733
Peripheral host T cells survive hematopoietic stem cell transplantation and promote graft-versus-host disease
J Clin Invest, 130 (9), 4624-4636
DOI 10.1172/JCI129965, PubMed 32516138
A qualitative analysis of infant and young child feeding practices in rural Rwanda
Public Health Nutr, 1-10 (in press)
DOI 10.1017/S1368980020001081, PubMed 32611464
An empirical study of factors associated with height-for-age z-scores of children aged 6-23 months in northwest Rwanda: the role of care practices related to child feeding and health
Br J Nutr, 1-12 (in press)
DOI 10.1017/S0007114520004961, PubMed 33298231
Safety and feasibility of rivaroxaban in deferred workup of patients with suspected deep vein thrombosis
Blood Adv, 4 (11), 2468-2476
DOI 10.1182/bloodadvances.2020001556, PubMed 32502267
Safety of a strategy combining D-dimer testing and whole-leg ultrasonography to rule out deep vein thrombosis
Blood Adv, 4 (20), 5002-5010
DOI 10.1182/bloodadvances.2020002173, PubMed 33057634
Outcome assessment by central adjudicators in randomised stroke trials: Simulation of differential and non-differential misclassification
Eur Stroke J, 5 (2), 174-183
DOI 10.1177/2396987320910047, PubMed 32637651
Pharmacokinetics and pharmacodynamics of a recombinant fusion protein linking activated coagulation factor VII with human albumin (rVIIa-FP) in patients with congenital FVII deficiency
Hematology, 25 (1), 17-25
DOI 10.1080/16078454.2019.1700329, PubMed 31852380
Aplastic anaemia
Tidsskr. Nor. Laegeforen., 140 (18), 1897-1900
Thrombosis and bleedings in a cohort of cancer patients treated with apixaban for venous thromboembolism
Thromb Res, 196, 238-244
DOI 10.1016/j.thromres.2020.08.042, PubMed 32919178
Effects of Production Region, Production Systems and Grape Type/Variety on Nutritional Quality Parameters of Table Grapes; Results from a UK Retail Survey
Foods, 9 (12)
DOI 10.3390/foods9121874, PubMed 33339243
Antitumor, Anti-Inflammatory and Antiallergic Effects of Agaricus blazei Mushroom Extract and the Related Medicinal Basidiomycetes Mushrooms, Hericium erinaceus and Grifolafrondosa: A Review of Preclinical and Clinical Studies
Nutrients, 12 (5)
DOI 10.3390/nu12051339, PubMed 32397163
Harnessing the Antiviral-Type Responses Induced by Immunostimulatory siRNAs for Cancer Immunotherapy
Methods Mol Biol, 2115, 281-287
DOI 10.1007/978-1-0716-0290-4_16, PubMed 32006407
Cardiac Dimensions and Function Are Not Altered among Females with the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Healthcare (Basel), 8 (4)
DOI 10.3390/healthcare8040406, PubMed 33081294
Adverse event management in the TOURMALINE-MM3 study of post-transplant ixazomib maintenance in multiple myeloma
Ann Hematol, 99 (8), 1793-1804
DOI 10.1007/s00277-020-04149-5, PubMed 32613281
Editor's Choice - European Society for Vascular Surgery (ESVS) 2021 Clinical Practice Guidelines on the Management of Venous Thrombosis
Eur J Vasc Endovasc Surg, 61 (1), 9-82
DOI 10.1016/j.ejvs.2020.09.023, PubMed 33334670
Design and Characterization of a New pVII Combinatorial Phage Display Peptide Library for Protease Substrate Mining Using Factor VII Activating Protease (FSAP) as Model
Chembiochem, 21 (13), 1875-1884
DOI 10.1002/cbic.201900705, PubMed 32180321
Targeting BCL-2 with venetoclax and dexamethasone in patients with relapsed/refractory t(11;14) multiple myeloma
Am J Hematol
DOI 10.1002/ajh.26083, PubMed 33368455
Management of comorbidities in haemophilia
Haemophilia, 27 Suppl 3, 37-45
DOI 10.1111/hae.14013, PubMed 32476243
Evaluating international Haemophilia Joint Health Score (HJHS) results combined with expert opinion: Options for a shorter HJHS
Haemophilia, 26 (6), 1072-1080
DOI 10.1111/hae.14180, PubMed 33058441
Efficacy and safety of oral panobinostat plus subcutaneous bortezomib and oral dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma (PANORAMA 3): an open-label, randomised, phase 2 study
Lancet Oncol, 22 (1), 142-154
DOI 10.1016/S1470-2045(20)30680-X, PubMed 33301738
Chronic lymphocytic leukemia and secondary hematological malignancies: A nation-wide cancer registry study
Eur J Haematol, 104 (6), 546-553
DOI 10.1111/ejh.13396, PubMed 32058605
Transformation to plasmablastic lymphoma in CLL upon ibrutinib treatment
BMJ Case Rep, 13 (9)
DOI 10.1136/bcr-2020-235816, PubMed 32994268
Joint health and treatment modalities in Nordic patients with moderate haemophilia A and B - The MoHem study
Haemophilia, 26 (5), 891-897
DOI 10.1111/hae.14114, PubMed 33021747
Left Ventricular Systolic Function in Long-Term Survivors of Allogeneic Hematopoietic Stem Cell Transplantation
JACC-Cardiooncol., 2 (3), 460-471
Left Ventricular Systolic Function in Long-Term Survivors of Allogeneic Hematopoietic Stem Cell Transplantation
JACC CardioOncol, 2 (3), 460-471
DOI 10.1016/j.jaccao.2020.06.011, PublikaID 352
Effects of modified Atkins diet on thyroid function in adult patients with pharmacoresistant epilepsy
Epilepsy Behav, 111, 107285
DOI 10.1016/j.yebeh.2020.107285, PubMed 32698106
Two Consecutive Episodes of Severe Delayed Hemolytic Transfusion Reaction in a Sickle Cell Disease Patient
Case Rep Hematol, 2020, 2765012
DOI 10.1155/2020/2765012, PubMed 32351743
Sickle cell disease and malaria: decreased exposure and asplenia can modulate the risk from Plasmodium falciparum
Malar J, 19 (1), 165
DOI 10.1186/s12936-020-03212-w, PubMed 32334583
Determinants of cardiorespiratory fitness in very long-term survivors of allogeneic hematopoietic stem cell transplantation: a national cohort study
Support Care Cancer, 29 (4), 1959-1967
DOI 10.1007/s00520-020-05644-1, PubMed 32827056
Macroscopic hematuria as a risk factor for hypertension in ageing people with hemophilia and a family history of hypertension
Medicine (Baltimore), 99 (9), e19339
DOI 10.1097/MD.0000000000019339, PubMed 32118768
Hematuria in aging men with hemophilia: Association with factor prophylaxis
Res Pract Thromb Haemost, 4 (2), 309-317
DOI 10.1002/rth2.12298, PubMed 32110762
Evolution of diagnostic workup and treatment for multiple myeloma 2013-2019
Eur J Haematol, 105 (4), 434-448
DOI 10.1111/ejh.13464, PubMed 32557833
Quality of life is maintained with ixazomib maintenance in post-transplant newly diagnosed multiple myeloma: The TOURMALINE-MM3 trial
Eur J Haematol, 104 (5), 443-458
DOI 10.1111/ejh.13379, PubMed 31880006
OCEAN: a randomized Phase III study of melflufen + dexamethasone to treat relapsed refractory multiple myeloma
Future Oncol, 16 (11), 631-641
DOI 10.2217/fon-2020-0024, PubMed 32141766
Isatuximab plus pomalidomide and dexamethasone in elderly patients with relapsed/refractory multiple myeloma: ICARIA-MM subgroup analysis
Haematologica (in press)
DOI 10.3324/haematol.2020.253450, PubMed 32586908
Redefining and measuring transplant conditioning intensity in current era: a study in acute myeloid leukemia patients
Bone Marrow Transplant, 55 (6), 1114-1125
DOI 10.1038/s41409-020-0803-y, PubMed 31996792
A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation
J Biol Chem (in press)
DOI 10.1074/jbc.RA120.015285, PubMed 33303632
Immune Thrombocytopenia (ITP): Current Limitations in Patient Management
Medicina (Kaunas), 56 (12)
DOI 10.3390/medicina56120667, PubMed 33266286
Thromboembolic events after high-intensity training during cisplatin-based chemotherapy for testicular cancer: Case reports and review of the literature
Int J Cancer, 147 (11), 3189-3198
DOI 10.1002/ijc.33151, PubMed 32525564
Coagulation factor V is a marker of tumor-infiltrating immune cells in breast cancer
Oncoimmunology, 9 (1), 1824644
DOI 10.1080/2162402X.2020.1824644, PubMed 33457104
Long-term outcomes of patients treated with rituximab as second-line treatment for adult immune thrombocytopenia - Follow-up of the RITP study
Br J Haematol, 191 (3), 460-465
DOI 10.1111/bjh.16672, PubMed 32342497
Anticoagulant interventions in hospitalized patients with COVID-19: A scoping review of randomized controlled trials and call for international collaboration
J Thromb Haemost, 18 (11), 2958-2967
DOI 10.1111/jth.15094, PubMed 32888372
Aflatoxins: Occurrence, Exposure, and Binding to Lactobacillus Species from the Gut Microbiota of Rural Ugandan Children
Microorganisms, 8 (3)
DOI 10.3390/microorganisms8030347, PubMed 32121365
Effect of wheat species (Triticum aestivum vs T. spelta), farming system (organic vs conventional) and flour type (wholegrain vs white) on composition of wheat flour - Results of a retail survey in the UK and Germany - 2. Antioxidant activity, and phenolic and mineral content
Food Chem X, 6, 100091
DOI 10.1016/j.fochx.2020.100091, PubMed 32420543
Effect of wheat species (Triticum aestivum vs T. spelta), farming system (organic vs conventional) and flour type (wholegrain vs white) on composition of wheat flour - Results of a retail survey in the UK and Germany - 3. Pesticide residue content
Food Chem X, 7, 100089
DOI 10.1016/j.fochx.2020.100089, PubMed 32637911
Effect of wheat species (Triticum aestivum vs T. spelta), farming system (organic vs conventional) and flour type (wholegrain vs white) on composition of wheat flour; results of a retail survey in the UK and Germany - 1. Mycotoxin content
Food Chem, 327, 127011
DOI 10.1016/j.foodchem.2020.127011, PubMed 32438263
Posttransplantation Lymphoproliferative Disease Treated by Retransplantation
Case Reports Immunol, 2020, 9403123
DOI 10.1155/2020/9403123, PubMed 32158568
Dietary intake and processes of behaviour change in a nutrition education intervention for pregnant women in rural Malawi: a cluster-randomised controlled trial
Public Health Nutr, 23 (13), 2345-2354
DOI 10.1017/S1368980020000294, PubMed 32419688