Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2017 from OUS - Department of Cardiology (Div CPD)
97 publications found
Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy
Sci Rep, 7 (1), 3490
DOI 10.1038/s41598-017-03625-9, PubMed 28615692
Wnt5a is elevated in heart failure and affects cardiac fibroblast function
J Mol Med (Berl), 95 (7), 767-777
DOI 10.1007/s00109-017-1529-1, PubMed 28357477
Heart rate prediction of outcome in heart failure following myocardial infarction depend on heart rhythm status an analysis from the high-risk myocardial infarction database initiative
Int J Cardiol, 249, 274-281
DOI 10.1016/j.ijcard.2017.09.182, PubMed 28964557
Left atrial volumetric assessment using a novel automated framework for 3D echocardiography: a multi-centre analysis
Eur Heart J Cardiovasc Imaging, 18 (9), 1008-1015
DOI 10.1093/ehjci/jew166, PubMed 27550659
Estimating Left Ventricular Filling Pressure by Echocardiography
J Am Coll Cardiol, 69 (15), 1937-1948
DOI 10.1016/j.jacc.2017.01.058, PubMed 28408024
In-hospital cost comparison between percutaneous pulmonary valve implantation and surgery
Eur J Cardiothorac Surg, 51 (4), 747-753
DOI 10.1093/ejcts/ezw378, PubMed 28007875
Morbidity outcomes after surgical aortic valve replacement
Open Heart, 4 (1), e000588
DOI 10.1136/openhrt-2017-000588, PubMed 28674629
Associations of brain-natriuretic peptide, high-sensitive troponin T, and high-sensitive C-reactive protein with outcomes in severe aortic stenosis
PLoS One, 12 (6), e0179304
DOI 10.1371/journal.pone.0179304, PubMed 28604834
Antihypertensive Treatment With β-Blockade in Patients With Asymptomatic Aortic Stenosis and Association With Cardiovascular Events
J Am Heart Assoc, 6 (12)
DOI 10.1161/JAHA.117.006709, PubMed 29180457
Recommendations on the Echocardiographic Assessment of Aortic Valve Stenosis: A Focused Update from the European Association of Cardiovascular Imaging and the American Society of Echocardiography
J Am Soc Echocardiogr, 30 (4), 372-392
DOI 10.1016/j.echo.2017.02.009, PubMed 28385280
A Centerline-Based Model Morphing Algorithm for Patient-Specific Finite Element Modeling of the Left Ventricle
IEEE Trans Biomed Eng, 65 (6), 1391-1398
DOI 10.1109/TBME.2017.2754980, PubMed 28945587
Estimating 3D Ventricular Shape From 2D Echocardiography: Feasibility and Effect of Noise
LECT NOTES COMPUT SC, 10263, 450-460
Semiautomated biventricular segmentation in three-dimensional echocardiography by coupled deformable surfaces
J Med Imaging (Bellingham), 4 (2), 024005
DOI 10.1117/1.JMI.4.2.024005, PubMed 28560243
Left Ventricular Contraction Pattern in Chronic Aortic Regurgitation and Preserved Ejection Fraction: Simultaneous Stress-Strain Analysis by Three-Dimensional Echocardiography
J Am Soc Echocardiogr, 30 (4), 422-430.e2
DOI 10.1016/j.echo.2016.11.012, PubMed 28065583
Soluble ST2 is associated with disease severity in arrhythmogenic right ventricular cardiomyopathy
Biomarkers, 22 (3-4), 367-371
DOI 10.1080/1354750X.2016.1278266, PubMed 28067540
Cognitive function among long-term survivors of heart transplantation
Clin Transplant, 31 (12)
DOI 10.1111/ctr.13143, PubMed 29055147
Cognitive function after heart transplantation: Comparing everolimus-based and calcineurin inhibitor-based regimens
Clin Transplant, 31 (4)
DOI 10.1111/ctr.12927, PubMed 28185318
Appropriateness criteria for the use of cardiovascular imaging in heart valve disease in adults: a European Association of Cardiovascular Imaging report of literature review and current practice
Eur Heart J Cardiovasc Imaging, 18 (5), 489-498
DOI 10.1093/ehjci/jew309, PubMed 28586420
Right ventricular remodeling in athletes and in arrhythmogenic cardiomyopathy
Scand Cardiovasc J, 52 (1), 13-19
DOI 10.1080/14017431.2017.1416158, PubMed 29254378
Pro-coagulant activity during exercise testing in patients with coronary artery disease
Thromb J, 15, 3
DOI 10.1186/s12959-016-0127-8, PubMed 28115916
Toll-Like Receptor 9 Promotes Survival in SERCA2a KO Heart Failure Mice
Mediators Inflamm, 2017, 9450439
DOI 10.1155/2017/9450439, PubMed 28490840
Rational and design of EuroCRT: an international observational study on multi-modality imaging and cardiac resynchronization therapy
Eur Heart J Cardiovasc Imaging, 18 (10), 1120-1127
DOI 10.1093/ehjci/jex021, PubMed 28329299
The years 2015-2016 in the European Heart Journal-Cardiovascular Imaging. Part I
Eur Heart J Cardiovasc Imaging, 18 (10), 1092-1098
DOI 10.1093/ehjci/jex192, PubMed 28984893
The year 2015-16 in the European Heart Journal-Cardiovascular Imaging. Part II
Eur Heart J Cardiovasc Imaging, 18 (12), 1322-1330
DOI 10.1093/ehjci/jex237, PubMed 29069381
The development and feasibility of a personal health-optimization system for people with bipolar disorder
BMC Med Inform Decis Mak, 17 (1), 102
DOI 10.1186/s12911-017-0481-x, PubMed 28693482
High-Intensity Interval Training in Patients With Heart Failure With Reduced Ejection Fraction
Circulation, 135 (9), 839-849
DOI 10.1161/CIRCULATIONAHA.116.022924, PubMed 28082387
Reduced inflammatory response by transcatheter, as compared to surgical aortic valve replacement
Scand Cardiovasc J, 52 (1), 43-50
DOI 10.1080/14017431.2017.1416157, PubMed 29233022
Frailty syndrome: an emerging clinical problem in the everyday management of clinical arrhythmias. The results of the European Heart Rhythm Association survey
Europace, 19 (11), 1896-1902
DOI 10.1093/europace/eux288, PubMed 29040554
Standardization of adult transthoracic echocardiography reporting in agreement with recent chamber quantification, diastolic function, and heart valve disease recommendations: an expert consensus document of the European Association of Cardiovascular Imaging
Eur Heart J Cardiovasc Imaging, 18 (12), 1301-1310
DOI 10.1093/ehjci/jex244, PubMed 29045589
Heart transplantation in arrhythmogenic right ventricular cardiomyopathy - Experience from the Nordic ARVC Registry
Int J Cardiol, 250, 201-206
DOI 10.1016/j.ijcard.2017.10.076, PubMed 29107359
Effect Modifications of Lipid-Lowering Therapy on Progression of Aortic Stenosis (from the Simvastatin and Ezetimibe in Aortic Stenosis [SEAS] Study)
Am J Cardiol, 121 (6), 739-745
DOI 10.1016/j.amjcard.2017.12.011, PubMed 29361285
Detection of intraoperative myocardial dysfunction by accelerometer during aortic valve replacement
Interact Cardiovasc Thorac Surg, 24 (2), 188-195
DOI 10.1093/icvts/ivw326, PubMed 28364479
Everolimus immunosuppression for renal protection, reduction of allograft vasculopathy and prevention of allograft rejection in de-novo heart transplant recipients: could we have it all?
Curr Opin Organ Transplant, 22 (3), 198-206
DOI 10.1097/MOT.0000000000000409, PubMed 28463861
Neurohormonal Blockade and Circulating Cardiovascular Biomarkers During Anthracycline Therapy in Breast Cancer Patients: Results From the PRADA (Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy) Study
J Am Heart Assoc, 6 (11)
DOI 10.1161/JAHA.117.006513, PubMed 29118031
Coronary computed tomography in heart transplant patients: detection of significant stenosis and cardiac allograft vasculopathy, image quality, and radiation dose
Acta Radiol, 59 (9), 1066-1073
DOI 10.1177/0284185117748354, PubMed 29260577
The predictive value of coronary artery calcium detected by computed tomography in a prospective study on cardiac allograft vasculopathy in heart transplant patients
Transpl Int, 31 (1), 82-91
DOI 10.1111/tri.13057, PubMed 28865096
The systolic paradox in hypertrophic cardiomyopathy
Open Heart, 4 (1), e000571
DOI 10.1136/openhrt-2016-000571, PubMed 28674623
Comprehensive multi-modality imaging approach in arrhythmogenic cardiomyopathy-an expert consensus document of the European Association of Cardiovascular Imaging
Eur Heart J Cardiovasc Imaging, 18 (3), 237-253
DOI 10.1093/ehjci/jew229, PubMed 28069601
Implantable cardioverter defibrillator use for primary prevention in ischaemic and non-ischaemic heart disease-indications in the post-DANISH trial era: results of the European Heart Rhythm Association survey
Europace, 19 (4), 660-664
DOI 10.1093/europace/eux089, PubMed 28431077
Patients with Cheyne-Stokes respiration and heart failure: patient tolerance after three-month discontinuation of treatment with adaptive servo-ventilation
Heart Vessels, 32 (8), 909-915
DOI 10.1007/s00380-017-0951-1, PubMed 28188451
Past and current cause-specific mortality in Eisenmenger syndrome
Eur Heart J, 38 (26), 2060-2067
DOI 10.1093/eurheartj/ehx201, PubMed 28430906
Epidemiological changes in Eisenmenger syndrome in the Nordic region in 1977-2012
Heart, 103 (17), 1353-1358
DOI 10.1136/heartjnl-2016-310979, PubMed 28450553
Cardiopulmonary Disease Development in Anti-RNA Polymerase III-positive Systemic Sclerosis: Comparative Analyses from an Unselected, Prospective Patient Cohort
J Rheumatol, 44 (4), 459-465
DOI 10.3899/jrheum.160867, PubMed 28089974
Cardiovascular Parameters to 2 years After Kidney Transplantation Following Early Switch to Everolimus Without Calcineurin Inhibitor Therapy: An Analysis of the Randomized ELEVATE Study
Transplantation, 101 (10), 2612-2620
DOI 10.1097/TP.0000000000001739, PubMed 28333860
Effect of interleukin-6 inhibition on coronary microvascular and endothelial function in myocardial infarction
Heart, 103 (19), 1521-1527
DOI 10.1136/heartjnl-2016-310875, PubMed 28432157
Determinants and Outcome of Decision Making Among Patients with Severe Aortic Stenosis
J Heart Valve Dis, 26 (4), 413-422
PubMed 29302940
Prognostic Value of Left Ventricular Deformation Parameters in Patients with Severe Aortic Stenosis: A Pilot Study of the Usefulness of Strain Echocardiography
J Am Soc Echocardiogr, 30 (8), 727-735.e1
DOI 10.1016/j.echo.2017.04.009, PubMed 28599826
Heart Rate and Rhythm and the Benefit of Beta-Blockers in Patients With Heart Failure
J Am Coll Cardiol, 69 (24), 2885-2896
DOI 10.1016/j.jacc.2017.04.001, PubMed 28467883
EVALUATION OF A MULTI-VIEW AUTOSTEREOSCOPIC REAL-TIME 3D ULTRASOUND SYSTEM FOR MINIMALLY INVASIVE CARDIAC SURGERY GUIDANCE
2017 IEEE 14TH INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING (ISBI 2017), 604-607
Long-term survival in patients with acute myocardial infarction and out-of-hospital cardiac arrest: A prospective cohort study
Resuscitation, 122, 41-47
DOI 10.1016/j.resuscitation.2017.11.047, PubMed 29155294
Gender differences in all-cause, cardiovascular and cancer mortality during long-term follow-up after acute myocardial infarction; a prospective cohort study
BMC Cardiovasc Disord, 17 (1), 75
DOI 10.1186/s12872-017-0508-3, PubMed 28288586
High-Sensitivity Troponin T vs I in Acute Coronary Syndrome: Prediction of Significant Coronary Lesions and Long-term Prognosis
Acta Bioquim. Clin. Latinoam., 51 (3), 395-407
Protocol update and preliminary results of EACVI/HFA Cardiac Oncology Toxicity (COT) Registry of the European Society of Cardiology
ESC Heart Fail, 4 (3), 312-318
DOI 10.1002/ehf2.12162, PubMed 28772051
Echo-Doppler estimation of left ventricular filling pressure: results of the multicentre EACVI Euro-Filling study
Eur Heart J Cardiovasc Imaging, 18 (9), 961-968
DOI 10.1093/ehjci/jex067, PubMed 28444160
The Clinical Use of Stress Echocardiography in Non-Ischaemic Heart Disease: Recommendations from the European Association of Cardiovascular Imaging and the American Society of Echocardiography
J Am Soc Echocardiogr, 30 (2), 101-138
DOI 10.1016/j.echo.2016.10.016, PubMed 28164802
Approach to cardio-oncologic patients with special focus on patients with cardiac implantable electronic devices planned for radiotherapy: results of the European Heart Rhythm Association survey
Europace, 19 (9), 1579-1584
DOI 10.1093/europace/eux195, PubMed 28934410
Combination of ECG and Echocardiography for Identification of Arrhythmic Events in Early ARVC
JACC-Cardiovasc. Imag., 10 (5), 504-513
Lower than expected burden of premature ventricular contractions impairs myocardial function
ESC Heart Fail, 4 (4), 585-594
DOI 10.1002/ehf2.12180, PubMed 29154430
Cardiac Assessment of Patients With Type 1 Diabetes Median 10 Years After Successful Simultaneous Pancreas and Kidney Transplantation Compared With Living Donor Kidney Transplantation
Transplantation, 101 (6), 1261-1267
DOI 10.1097/TP.0000000000001274, PubMed 27467687
Exercise systolic blood pressure at moderate workload predicts cardiovascular disease and mortality through 35 years of follow-up in healthy, middle-aged men
Blood Press, 26 (4), 229-236
DOI 10.1080/08037051.2017.1291276, PubMed 28276720
Increased Secondary/Primary Bile Acid Ratio in Chronic Heart Failure
J Card Fail, 23 (9), 666-671
DOI 10.1016/j.cardfail.2017.06.007, PubMed 28688889
Medical and psychosocial factors and unfavourable low-density lipoprotein cholesterol control in coronary patients
Eur J Prev Cardiol, 24 (9), 981-989
DOI 10.1177/2047487317693134, PubMed 28196429
Effect of Calcineurin Inhibitor-Free, Everolimus-Based Immunosuppressive Regimen on Albuminuria and Glomerular Filtration Rate After Heart Transplantation
Transplantation, 101 (11), 2793-2800
DOI 10.1097/TP.0000000000001706, PubMed 28230646
Comparison of Electrocardiography Markers and Speckle Tracking Echocardiography for Assessment of Left Ventricular Myocardial Scar Burden in Patients With Previous Myocardial Infarction
Am J Cardiol, 119 (9), 1307-1312
DOI 10.1016/j.amjcard.2017.01.020, PubMed 28274572
The Notch Ligands DLL1 and Periostin Are Associated with Symptom Severity and Diastolic Function in Dilated Cardiomyopathy
J Cardiovasc Transl Res, 10 (4), 401-410
DOI 10.1007/s12265-017-9748-y, PubMed 28474304
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture
Cell Rep, 18 (1), 82-92
DOI 10.1016/j.celrep.2016.12.009, PubMed 28052262
A 50 year old man with proximal power failure and heart disease
Tidsskr. Nor. Laegeforen., 137 (16), 1206-1209
Thyroid and Glucocorticoid Hormones Promote Functional T-Tubule Development in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Circ Res, 121 (12), 1323-1330
DOI 10.1161/CIRCRESAHA.117.311920, PubMed 28974554
Fast and Fully Automatic Left Ventricular Segmentation and Tracking in Echocardiography Using Shape-Based B-Spline Explicit Active Surfaces
IEEE Trans Med Imaging, 36 (11), 2287-2296
DOI 10.1109/TMI.2017.2734959, PubMed 28783626
Reproducibility of an extensive self-report questionnaire used in secondary coronary prevention
Scand J Public Health, 45 (3), 269-276
DOI 10.1177/1403494816688375, PubMed 28181463
The role of cardiac rehabilitation in secondary prevention after coronary events
Eur J Prev Cardiol, 24 (13), 1360-1368
DOI 10.1177/2047487317719355, PubMed 28664773
Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function
Basic Res Cardiol, 112 (3), 20
DOI 10.1007/s00395-017-0610-9, PubMed 28258298
Effect of everolimus vs calcineurin inhibitors on quality of life in heart transplant recipients during a 3-year follow-up: Results of a randomized controlled trial (SCHEDULE)
Clin Transplant, 31 (9)
DOI 10.1111/ctr.13038, PubMed 28640529
Long-term Change in the Risk of Skin Cancer After Organ Transplantation: A Population-Based Nationwide Cohort Study
JAMA Dermatol, 153 (12), 1270-1277
DOI 10.1001/jamadermatol.2017.2984, PubMed 29049612
Focused cardiac ultrasound by unselected residents-the challenges
BMC Med Imaging, 17 (1), 22
DOI 10.1186/s12880-017-0191-y, PubMed 28259149
Atrial fibrillation and the risk for myocardial infarction, all-cause mortality and heart failure: A systematic review and meta-analysis
Eur J Prev Cardiol, 24 (14), 1555-1566
DOI 10.1177/2047487317715769, PubMed 28617620
Connective tissue growth factor and bone morphogenetic protein 2 are induced following myocardial ischemia in mice and humans
Scand J Clin Lab Invest, 77 (5), 321-331
DOI 10.1080/00365513.2017.1318447, PubMed 28460577
Persistence of Cardiac Remodeling in Preadolescents With Fetal Growth Restriction
Circ Cardiovasc Imaging, 10 (1)
DOI 10.1161/CIRCIMAGING.116.005270, PubMed 28093413
Left ventricular dysfunction is related to the presence and extent of a septal flash in patients with right ventricular pacing
Europace, 19 (2), 289-296
DOI 10.1093/europace/euw020, PubMed 28175277
Clinical practice of contrast echocardiography: recommendation by the European Association of Cardiovascular Imaging (EACVI) 2017
Eur Heart J Cardiovasc Imaging, 18 (11), 1205-1205af
DOI 10.1093/ehjci/jex182, PubMed 28950366
The alternative complement pathway is dysregulated in patients with chronic heart failure
Sci Rep, 7, 42532
DOI 10.1038/srep42532, PubMed 28195242
Declining Risk of Sudden Death in Heart Failure
N Engl J Med, 377 (1), 41-51
DOI 10.1056/NEJMoa1609758, PubMed 28679089
Evaluation of left ventricular diastolic function: state of the art after 35 years with Doppler assessment
J Echocardiogr, 16 (2), 55-64
DOI 10.1007/s12574-017-0364-2, PubMed 29236226
Fractional Flow Reserve-Guided Multivessel Angioplasty in Myocardial Infarction
N Engl J Med, 376 (13), 1234-1244
DOI 10.1056/NEJMoa1701067, PubMed 28317428
EACVI appropriateness criteria for the use of transthoracic echocardiography in adults: a report of literature and current practice review
Eur Heart J Cardiovasc Imaging, 18 (11), 1191-1204
DOI 10.1093/ehjci/jew333, PubMed 28329307
Obstructive and restrictive pulmonary dysfunction in long-term lymphoma survivors after high-dose therapy with autologous stem cell transplantation
Acta Oncol, 57 (6), 773-781
DOI 10.1080/0284186X.2017.1406137, PubMed 29171324
Geometry as a Confounder When Assessing Ventricular Systolic Function: Comparison Between Ejection Fraction and Strain
J Am Coll Cardiol, 70 (8), 942-954
DOI 10.1016/j.jacc.2017.06.046, PubMed 28818204
Medical and sociodemographic factors predict persistent smoking after coronary events
BMC Cardiovasc Disord, 17 (1), 241
DOI 10.1186/s12872-017-0676-1, PubMed 28877684
Unfavourable risk factor control after coronary events in routine clinical practice
BMC Cardiovasc Disord, 17 (1), 40
DOI 10.1186/s12872-016-0387-z, PubMed 28109259
Optimal blood pressure control after coronary events: the challenge remains
J Am Soc Hypertens, 11 (12), 823-830
DOI 10.1016/j.jash.2017.10.007, PubMed 29128603
Left atrial appendage occluder implantation in Europe: indications and anticoagulation post-implantation. Results of the European Heart Rhythm Association Survey
Europace, 19 (10), 1737-1742
DOI 10.1093/europace/eux254, PubMed 29016910
An integrative appraisal of mechano-electric feedback mechanisms in the heart
Prog Biophys Mol Biol, 130 (Pt B), 404-417
DOI 10.1016/j.pbiomolbio.2017.08.008, PubMed 28851517
Whole exome sequencing with genomic triangulation implicates CDH2-encoded N-cadherin as a novel pathogenic substrate for arrhythmogenic cardiomyopathy
Congenit Heart Dis, 12 (2), 226-235
DOI 10.1111/chd.12462, PubMed 28326674
Outcome of Alcohol Septal Ablation in Mildly Symptomatic Patients With Hypertrophic Obstructive Cardiomyopathy: A Long-Term Follow-Up Study Based on the Euro-Alcohol Septal Ablation Registry
J Am Heart Assoc, 6 (5)
DOI 10.1161/JAHA.117.005735, PubMed 28512112
vWF/ADAMTS13 is associated with on-aspirin residual platelet reactivity and clinical outcome in patients with stable coronary artery disease
Thromb J, 15, 28
DOI 10.1186/s12959-017-0151-3, PubMed 29200971
Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study
Eur J Heart Fail, 20 (2), 268-277
DOI 10.1002/ejhf.988, PubMed 28960777
Immediate response in markers of inflammation and angiogenesis during exercise: a randomised cross-over study in heart transplant recipients
Open Heart, 4 (2), e000635
DOI 10.1136/openhrt-2017-000635, PubMed 29225901