Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2021 from OUS - Institute for Surgical Research ISR

34 publications found

Abadpour S, Wang CC, Niemi EM, Scholz H (2021)
Tissue Engineering Strategies for Improving Beta Cell Transplantation Outcome
Curr. Transplant. Rep., 8 (3), 205-219
DOI 10.1007/s40472-021-00333-2

Azevedo ACA, Barros MVL, Klaboe LG, Edvardsen T, Costa HS, Paixao GMM, Junior ORS, Nunes MCP, Rocha MOC (2021)
Association between myocardial mechanical dispersion and ventricular arrhythmogenicity in chagas cardiomyopathy
Int J Cardiovasc Imaging, 37 (9), 2727-2734
DOI 10.1007/s10554-021-02246-8, PubMed 33881664

Berishvili E, Casiraghi F, Amarelli C, Scholz H, Piemonti L, Berney T, Montserrat N (2021)
Mini-organs forum: how to advance organoid technology to organ transplant community
Transpl Int, 34 (9), 1588-1593
DOI 10.1111/tri.13988, PubMed 34448263

Bjerring AW, Edvardsen T, Sarvari SI, Solberg EE (2021)
A. Bjerring og medarbeiderne svarer
Tidsskr Nor Laegeforen, 141
DOI 10.4045/tidsskr.21.0583, PubMed 34505484

Bjørkavoll-Bergseth M, Erevik CB, Kleiven Ø, Eijsvogels TMH, Skadberg Ø, Frøysa V, Wiktorski T, Auestad B, Edvardsen T, Moberg Aakre K, Ørn S (2021)
Determinants of Interindividual Variation in Exercise-Induced Cardiac Troponin I Levels
J Am Heart Assoc, 10 (17), e021710
DOI 10.1161/JAHA.121.021710, PubMed 34459237

Bularga A, Saraste A, Fontes-Carvalho R, Holte E, Cameli M, Michalski B, Williams MC, Podlesnikar T, D'Andrea A, Stankovic I, Mills NL, Manka R, Newby DE, Schultz-Menger J, Haugaa KH, Dweck MR (2021)
EACVI survey on investigations and imaging modalities in chronic coronary syndromes
Eur Heart J Cardiovasc Imaging, 22 (1), 1-7
DOI 10.1093/ehjci/jeaa300, PubMed 33165600

Collet JP, Thiele H, Barbato E, Barthélémy O, Bauersachs J, Bhatt DL, Dendale P, Dorobantu M, Edvardsen T, Folliguet T, Gale CP, Gilard M, Jobs A, Jüni P, Lambrinou E, Lewis BS, Mehilli J, Meliga E, Merkely B, Mueller C, Roffi M, Rutten FH, Sibbing D, Siontis GCM, ESC Scientific Document Group (2021)
2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation
Eur Heart J, 42 (14), 1289-1367
DOI 10.1093/eurheartj/ehaa575, PubMed 32860058

Degtiarova G, Claus P, Duchenne J, Bogaert J, Nuyts J, Vöros G, Willems R, Larsen CK, Aalen JM, Fjeld JG, Stokke C, Hopp E, Smiseth OA, Voigt JU, Gheysens O (2021)
Left ventricular regional glucose metabolism in combination with septal scar extent identifies CRT responders
Eur J Nucl Med Mol Imaging, 48 (8), 2437-2446
DOI 10.1007/s00259-020-05161-7, PubMed 33416956

Galli E, Le Rolle V, Smiseth OA, Duchenne J, Aalen JM, Larsen CK, Sade EA, Hubert A, Anilkumar S, Penicka M, Linde C, Leclercq C, Hernandez A, Voigt JU, Donal E (2021)
Importance of Systematic Right Ventricular Assessment in Cardiac Resynchronization Therapy Candidates: A Machine Learning Approach
J Am Soc Echocardiogr, 34 (5), 494-502
DOI 10.1016/j.echo.2020.12.025, PubMed 33422667

Galli E, Oger E, Aalen JM, Duchenne J, Larsen CK, Sade E, Hubert A, Gallard A, Penicka M, Linde C, Le Rolle V, Hernandez A, Leclercq C, Voigt JU, Smiseth OA, Donal E (2021)
Left atrial strain is a predictor of left ventricular systolic and diastolic reverse remodelling in CRT candidates
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jeab163, PubMed 34432006

Galli E, Smiseth OA, Aalen JM, Larsen CK, Sade E, Hubert A, Anilkumar S, Penicka M, Linde C, Le Rolle V, Hernandez A, Leclercq C, Duchenne J, Voigt JU, Donal E (2021)
Prognostic utility of the assessment of diastolic function in patients undergoing cardiac resynchronization therapy
Int J Cardiol, 331, 144-151
DOI 10.1016/j.ijcard.2021.01.046, PubMed 33535079

Ghila L, Legøy TA, Mathisen AF, Abadpour S, Paulo JA, Scholz H, Ræder H, Chera S (2021)
Chronically Elevated Exogenous Glucose Elicits Antipodal Effects on the Proteome Signature of Differentiating Human iPSC-Derived Pancreatic Progenitors
Int J Mol Sci, 22 (7)
DOI 10.3390/ijms22073698, PubMed 33918250

Hubert A, Gallard A, Rolle VL, Smiseth OA, Leclercq C, Voigt JU, Galli E, Galand V, Hernandez A, Donal E (2021)
Left ventricular strain for predicting the response to cardiac resynchronization therapy: two methods for one question
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jeaa422, PubMed 33517397

Inoue K, Khan FH, Remme EW, Ohte N, García-Izquierdo E, Chetrit M, Moñivas-Palomero V, Mingo-Santos S, Andersen ØS, Gude E, Andreassen AK, Wang TKM, Kikuchi S, Stugaard M, Ha JW, Klein AL, Nagueh SF, Smiseth OA (2021)
Determinants of left atrial reservoir and pump strain and use of atrial strain for evaluation of left ventricular filling pressure
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jeaa415, PubMed 33496314

Karvelsson ST, Sigurdsson A, Seip K, Grinde MT, Wang Q, Johannsson F, Mælandsmo GM, Moestue SA, Rolfsson O, Halldorsson S (2021)
EMT-Derived Alterations in Glutamine Metabolism Sensitize Mesenchymal Breast Cells to mTOR Inhibition
Mol Cancer Res, 19 (9), 1546-1558
DOI 10.1158/1541-7786.MCR-20-0962, PubMed 34088869

Karvelsson ST, Wang Q, Hilmarsdottir B, Sigurdsson A, Moestue SA, Mælandsmo GM, Halldorsson S, Gudmundsson S, Rolfsson O (2021)
Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer
NPJ Syst Biol Appl, 7 (1), 36
DOI 10.1038/s41540-021-00195-5, PubMed 34535676

Kasiakogias A, Rosei EA, Camafort M, Ehret G, Faconti L, Ferreira JP, Brguljan J, Januszewicz A, Kahan T, Manolis A, Tsioufis K, Weber T, von Lueder TG, Smiseth OA, Wachtell K, Kjeldsen SE, Zannad F, Mancia G, Kreutz R (2021)
Hypertension and heart failure with preserved ejection fraction: position paper by the European Society of Hypertension
J Hypertens, 39 (8), 1522-1545
DOI 10.1097/HJH.0000000000002910, PubMed 34102660

Krogh MR, Halvorsen PS, Grymyr OHN, Bergsland J, Elle OJ, Fosse E, Remme EW (2021)
Continuous Estimation of Acute Changes in Preload Using Epicardially Attached Accelerometers
IEEE Trans Biomed Eng, 68 (7), 2067-2075
DOI 10.1109/TBME.2020.3020358, PubMed 32866091

Lanari J, Hagness M, Sartori A, Rosso E, Gringeri E, Dueland S, Cillo U, Line PD (2021)
Liver transplantation versus liver resection for colorectal liver metastasis: a survival benefit analysis in patients stratified according to tumor burden score
Transpl Int, 34 (9), 1722-1732
DOI 10.1111/tri.13981, PubMed 34448271

Lauritzen KH, Olsen MB, Ahmed MS, Yang K, Rinholm JE, Bergersen LH, Esbensen QY, Sverkeli LJ, Ziegler M, Attramadal H, Halvorsen B, Aukrust P, Yndestad A (2021)
Instability in NAD+ metabolism leads to impaired cardiac mitochondrial function and communication
Elife, 10
DOI 10.7554/eLife.59828, PubMed 34343089

Melichova D, Nguyen TM, Salte IM, Klaeboe LG, Sjøli B, Karlsen S, Dahlslett T, Leren IS, Edvardsen T, Brunvand H, Haugaa KH (2021)
Strain echocardiography improves prediction of arrhythmic events in ischemic and non-ischemic dilated cardiomyopathy
Int J Cardiol, 342, 56-62
DOI 10.1016/j.ijcard.2021.07.044, PubMed 34324947

Nguyen TT, Espinoza AW, Hyler S, Remme EW, D'hooge J, Hoff L (2021)
Myocardial Strain Measured by Epicardial Transducers-Comparison Between Velocity Estimators
Ultrasound Med Biol, 47 (5), 1377-1396
DOI 10.1016/j.ultrasmedbio.2021.01.012, PubMed 33593489

Odland HH, Villegas-Martinez M, Ross S, Holm T, Cornelussen R, Remme EW, Kongsgard E (2021)
Shortening of time-to-peak left ventricular pressure rise (Td) in cardiac resynchronization therapy
ESC Heart Fail
DOI 10.1002/ehf2.13601, PubMed 34514746

Ostvik A, Salte IM, Smistad E, Nguyen TM, Melichova D, Brunvand H, Haugaa K, Edvardsen T, Grenne B, Lovstakken L (2021)
Myocardial Function Imaging in Echocardiography Using Deep Learning
IEEE Trans Med Imaging, 40 (5), 1340-1351
DOI 10.1109/TMI.2021.3054566, PubMed 33493114

Quattrone A, Lie OH, Nestaas E, de Lange C, Try K, Lindberg HL, Skulstad H, Erikssen G, Edvardsen T, Haugaa K, Estensen ME (2021)
Impact of pregnancy and risk factors for ventricular arrhythmias in women with tetralogy of Fallot
Open Heart, 8 (1)
DOI 10.1136/openhrt-2020-001400, PubMed 33414183

Sitges M, Ajmone Marsan N, Cameli M, D'Andrea A, Carvalho RF, Holte E, Michalski B, Podlesnikar T, Popescu BA, Schulz-Menger J, Stankovic I, Haugaa KH, Dweck MR (2021)
EACVI survey on the evaluation of left ventricular diastolic function
Eur Heart J Cardiovasc Imaging, 22 (10), 1098-1105
DOI 10.1093/ehjci/jeab087, PubMed 33969402

Skaga E, Skretteberg MA, Johannesen TB, Brandal P, Vik-Mo EO, Helseth E, Langmoen IA (2021)
Real-world validity of randomized controlled phase III trials in newly diagnosed glioblastoma: to whom do the results of the trials apply?
Neurooncol Adv, 3 (1), vdab008
DOI 10.1093/noajnl/vdab008, PubMed 33665615

Sletten OJ, Aalen JM, Izci H, Duchenne J, Remme EW, Larsen CK, Hopp E, Galli E, Sirnes PA, Kongsgard E, Donal E, Voigt JU, Smiseth OA, Skulstad H (2021)
Lateral Wall Dysfunction Signals Onset of Progressive Heart Failure in Left Bundle Branch Block
JACC Cardiovasc Imaging (in press)
DOI 10.1016/j.jcmg.2021.04.017, PubMed 34147454

Smiseth OA, Baron T, Marino PN, Marwick TH, Flachskampf FA (2021)
Imaging of the left atrium: pathophysiology insights and clinical utility
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jeab191, PubMed 34601594

Smiseth OA, Donal E, Penicka M, Sletten OJ (2021)
How to measure left ventricular myocardial work by pressure-strain loops
Eur Heart J Cardiovasc Imaging, 22 (3), 259-261
DOI 10.1093/ehjci/jeaa301, PubMed 33257982

Svensson A, Platonov PG, Haugaa KH, Zareba W, Jensen HK, Bundgaard H, Gilljam T, Madsen T, Hansen J, Dejgaard LA, Karlsson LO, Gréen A, Polonsky B, Edvardsen T, Svendsen JH, Gunnarsson C (2021)
Genetic Variant Score and Arrhythmogenic Right Ventricular Cardiomyopathy Phenotype in Plakophilin-2 Mutation Carriers
Cardiology (in press)
DOI 10.1159/000519231, PubMed 34469894

Vahanian A, Beyersdorf F, Praz F, Milojevic M, Baldus S, Bauersachs J, Capodanno D, Conradi L, De Bonis M, De Paulis R, Delgado V, Freemantle N, Gilard M, Haugaa KH, Jeppsson A, Jüni P, Pierard L, Prendergast BD, Sádaba JR, Tribouilloy C, Wojakowski W, (2021)
2021 ESC/EACTS Guidelines for the management of valvular heart disease
Eur Heart J (in press)
DOI 10.1093/eurheartj/ehab395, PubMed 34453165

Yang DJ, Shi JH, Xia ZP, Guo WZ, Ahmed MS, Zhang SJ (2021)
Hepatic connective tissue growth factor expression and regulation differ between non-steatotic and non-alcoholic steatotic livers from brain-dead donor
Sci Rep, 11 (1), 3857
DOI 10.1038/s41598-021-83516-2, PubMed 33594198

Zhou AX, Mondal T, Tabish AM, Abadpour S, Ericson E, Smith DM, Knöll R, Scholz H, Kanduri C, Tyrberg B, Althage M (2021)
The long noncoding RNA TUNAR modulates Wnt signaling and regulates human β-cell proliferation
Am J Physiol Endocrinol Metab, 320 (4), E846-E857
DOI 10.1152/ajpendo.00335.2020, PubMed 33682459

 
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