Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2018 from OUS - Institute for Experimental Medical Research (IEMR)
31 publications found
Bromine inhalation mimics ischemia-reperfusion cardiomyocyte injury and calpain activation in rats
Am J Physiol Heart Circ Physiol, 316 (1), H212-H223
DOI 10.1152/ajpheart.00652.2017, PubMed 30379573
Conflicting vascular and metabolic impact of the IL-33/sST2 axis
Cardiovasc Res, 114 (12), 1578-1594
DOI 10.1093/cvr/cvy166, PubMed 29982301
In Silico Analysis of Differential Gene Expression in Three Common Rat Models of Diastolic Dysfunction
Front Cardiovasc Med, 5, 11
DOI 10.3389/fcvm.2018.00011, PubMed 29556499
The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling
PLoS One, 13 (7), e0201422
DOI 10.1371/journal.pone.0201422, PubMed 30052659
Diagnostic and prognostic properties of procalcitonin in patients with acute dyspnea: Data from the ACE 2 Study
Clin Biochem, 59, 62-68
DOI 10.1016/j.clinbiochem.2018.07.006, PubMed 30028971
TBC1D5 controls the GTPase cycle of Rab7b
J Cell Sci, 131 (17)
DOI 10.1242/jcs.216630, PubMed 30111580
Sweet, yet underappreciated: Proteoglycans and extracellular matrix remodeling in heart disease
Matrix Biol, 75-76, 286-299
DOI 10.1016/j.matbio.2018.01.001, PubMed 29337052
Arrhythmia initiation in catecholaminergic polymorphic ventricular tachycardia type 1 depends on both heart rate and sympathetic stimulation
PLoS One, 13 (11), e0207100
DOI 10.1371/journal.pone.0207100, PubMed 30399185
Myocardial fibrosis
Tidsskr Nor Laegeforen, 138 (16)
DOI 10.4045/tidsskr.17.1027, PubMed 30344312
O-GlcNAc site-mapping of liver X receptor-α and O-GlcNAc transferase
Biochem Biophys Res Commun, 499 (2), 354-360
DOI 10.1016/j.bbrc.2018.03.164, PubMed 29577901
Human ISL1+ Ventricular Progenitors Self-Assemble into an In Vivo Functional Heart Patch and Preserve Cardiac Function Post Infarction
Mol Ther, 26 (7), 1644-1659
DOI 10.1016/j.ymthe.2018.02.012, PubMed 29606507
STIM1 R304W causes muscle degeneration and impaired platelet activation in mice
Cell Calcium, 76, 87-100
DOI 10.1016/j.ceca.2018.10.001, PubMed 30390422
IL-33 (Interleukin 33)/sST2 Axis in Hypertension and Heart Failure
Hypertension, 72 (4), 818-828
DOI 10.1161/HYPERTENSIONAHA.118.11157, PubMed 30354724
The combination of maternal KIR-B and fetal HLA-C2 is associated with decidua basalis acute atherosis in pregnancies with preeclampsia
J Reprod Immunol, 129, 23-29
DOI 10.1016/j.jri.2018.07.005, PubMed 30055414
Dyadic Plasticity in Cardiomyocytes
Front Physiol, 9, 1773
DOI 10.3389/fphys.2018.01773, PubMed 30618792
Cerebral blood flow alteration following acute myocardial infarction in mice
Biosci Rep, 38 (5)
DOI 10.1042/BSR20180382, PubMed 30061176
Ryanodine receptor dispersion disrupts Ca2+ release in failing cardiac myocytes
Elife, 7
DOI 10.7554/eLife.39427, PubMed 30375974
Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology
Eur Heart J, 39 (48), 4243-4254
DOI 10.1093/eurheartj/ehy596, PubMed 30295797
A novel method for high precision aortic constriction that allows for generation of specific cardiac phenotypes in mice
Cardiovasc Res, 114 (12), 1680-1690
DOI 10.1093/cvr/cvy141, PubMed 29878127
Classical Cardiovascular Risk Markers in Pregnancy and Associations to Uteroplacental Acute Atherosis
Hypertension, 72 (3), 695-702
DOI 10.1161/HYPERTENSIONAHA.118.10964, PubMed 30354752
Patterns of Invasive Growth in Malignant Gliomas-The Hippocampus Emerges as an Invasion-Spared Brain Region
Neoplasia, 20 (7), 643-656
DOI 10.1016/j.neo.2018.04.001, PubMed 29793116
Prognostic and diagnostic significance of mid-regional pro-atrial natriuretic peptide in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: data from the ACE 2 Study
Biomarkers, 23 (7), 654-663
DOI 10.1080/1354750X.2018.1474258, PubMed 29733687
Auto-antibodies against the angiotensin II type I receptor in women with uteroplacental acute atherosis and preeclampsia at delivery and several years postpartum
J Reprod Immunol, 128, 23-29
DOI 10.1016/j.jri.2018.05.008, PubMed 29843114
3D dSTORM imaging reveals novel detail of ryanodine receptor localization in rat cardiac myocytes
J Physiol, 597 (2), 399-418
DOI 10.1113/JP277360, PubMed 30412283
OGT (O-GlcNAc Transferase) Selectively Modifies Multiple Residues Unique to Lamin A
Cells, 7 (5)
DOI 10.3390/cells7050044, PubMed 29772801
Hypokalemia-Induced Arrhythmias and Heart Failure: New Insights and Implications for Therapy
Front Physiol, 9, 1500
DOI 10.3389/fphys.2018.01500, PubMed 30464746
Contractile responses to endothelin-1 are regulated by PKC phosphorylation of cardiac myosin binding protein-C in rat ventricular myocytes
J Mol Cell Cardiol, 117, 1-18
DOI 10.1016/j.yjmcc.2018.02.012, PubMed 29470978
A fundamental catalytic difference between zinc and manganese dependent enzymes revealed in a bacterial isatin hydrolase
Sci Rep, 8 (1), 13104
DOI 10.1038/s41598-018-31259-y, PubMed 30166577
Haemodynamic outcomes during piston-based mechanical CPR with or without active decompression in a porcine model of cardiac arrest
Scand J Trauma Resusc Emerg Med, 26 (1), 31
DOI 10.1186/s13049-018-0496-z, PubMed 29690910
Structural Origin of Metal Specificity in Isatin Hydrolase from Labrenzia aggregata Investigated by Computer Simulations
Chemistry, 24 (20), 5074-5077
DOI 10.1002/chem.201705159, PubMed 29243856
Associations between Cytokine Levels and CYP3A4 Phenotype in Patients with Rheumatoid Arthritis
Drug Metab Dispos, 46 (10), 1384-1389
DOI 10.1124/dmd.118.082065, PubMed 29991576