Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2021 from OUS - Department of Pediatric Research

34 publications found

Almaas R, Saugstad OD (2021)
50 Years Ago in TheJournalofPediatrics: Hepatopulmonary Syndrome: Transplantation Is the Big Difference
J Pediatr, 229, 69
DOI 10.1016/j.jpeds.2020.08.074, PubMed 33487230

Almaas R, Saugstad OD (2021)
50 Years Ago in TheJournalofPediatrics: Diagnosis of Self-Mutilation and Hyperuricemia
J Pediatr, 237, 86
DOI 10.1016/j.jpeds.2021.07.034, PubMed 34563325

Almaas R, Saugstad OD (2021)
50 Years Ago in TheJournalofPediatrics: Pregnancy in Women with Galactosemia
J Pediatr, 233, 118
DOI 10.1016/j.jpeds.2021.02.032, PubMed 34030831

Andersen E, Chollet ME, Sletten M, Stavik B, Skarpen E, Backe PH, Thiede B, Glosli H, Henriksson CE, Iversen N (2021)
Molecular Characterization of Two Homozygous Factor VII Variants Associated with Intracranial Bleeding
Thromb Haemost
DOI 10.1055/a-1450-8568, PubMed 33742435

Berland S, Rustad CF, Bentsen MHL, Wollen EJ, Turowski G, Johansson S, Houge G, Haukanes BI (2021)
Double paternal uniparental isodisomy 7 and 15 presenting with Beckwith-Wiedemann spectrum features
Cold Spring Harb Mol Case Stud (in press)
DOI 10.1101/mcs.a006113, PubMed 34615670

Bonner ER, Waszak SM, Grotzer MA, Mueller S, Nazarian J (2021)
Mechanisms of imipridones in targeting mitochondrial metabolism in cancer cells
Neuro Oncol, 23 (4), 542-556
DOI 10.1093/neuonc/noaa283, PubMed 33336683

Bruckner M, Lista G, Saugstad OD, Schmölzer GM (2021)
Delivery Room Management of Asphyxiated Term and Near-Term Infants
Neonatology, 118 (4), 487-499
DOI 10.1159/000516429, PubMed 34023837

Chen A, Kristiansen CK, Hong Y, Kianian A, Fang EF, Sullivan GJ, Wang J, Li X, Bindoff LA, Liang KX (2021)
Nicotinamide Riboside and Metformin Ameliorate Mitophagy Defect in Induced Pluripotent Stem Cell-Derived Astrocytes With POLG Mutations
Front Cell Dev Biol, 9, 737304
DOI 10.3389/fcell.2021.737304, PubMed 34631714

Christensen AH, Nygaard S, Rolid K, Nytrøen K, Gullestad L, Fiane A, Thaulow E, Døhlen G, Saul JP, Wyller VBB (2021)
Early Signs of Sinoatrial Reinnervation in the Transplanted Heart
Transplantation, 105 (9), 2086-2096
DOI 10.1097/TP.0000000000003580, PubMed 33323767

Convery N, Samardzhieva I, Stormonth-Darling JM, Harrison S, Sullivan GJ, Gadegaard N (2021)
3D Printed Tooling for Injection Molded Microfluidics
Macromol. Mater. Eng., 2100464
DOI 10.1002/mame.202100464

Fernandez-Checa JC, Bagnaninchi P, Ye H, Sancho-Bru P, Falcon-Perez JM, Royo F, Garcia-Ruiz C, Konu O, Miranda J, Lunov O, Dejneka A, Elfick A, McDonald A, Sullivan GJ, Aithal GP, Lucena MI, Andrade RJ, Fromenty B, Kranendonk M, Cubero FJ, Nelson LJ (2021)
Advanced preclinical models for evaluation of drug-induced liver injury - consensus statement by the European Drug-Induced Liver Injury Network [PRO-EURO-DILI-NET]
J Hepatol, 75 (4), 935-959
DOI 10.1016/j.jhep.2021.06.021, PubMed 34171436

Glosli H, Bisogno G, Kelsey A, Chisholm JC, Gaze M, Kolb F, McHugh K, Shipley J, Gallego S, Merks JHM, Smeele LE, Mandeville H, Ferrari A, Minard-Colin V, Corradini N, Jenney M, Zanetti I, De Salvo GL, Orbach D, EpSSG members (2021)
Non-parameningeal head and neck rhabdomyosarcoma in children, adolescents, and young adults: Experience of the European paediatric Soft tissue sarcoma Study Group (EpSSG) - RMS2005 study
Eur J Cancer, 151, 84-93
DOI 10.1016/j.ejca.2021.04.007, PubMed 33971448

Hajdarevic R, Lande A, Rekeland I, Rydland A, Strand EB, Sosa DD, Creary LE, Mella O, Egeland T, Saugstad OD, Fluge Ø, Lie BA, Viken MK (2021)
Fine mapping of the major histocompatibility complex (MHC) in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) suggests involvement of both HLA class I and class II loci
Brain Behav Immun, 98, 101-109
DOI 10.1016/j.bbi.2021.08.219, PubMed 34403736

Harrison SP, Baumgarten SF, Verma R, Lunov O, Dejneka A, Sullivan GJ (2021)
Liver Organoids: Recent Developments, Limitations and Potential
Front Med (Lausanne), 8, 574047
DOI 10.3389/fmed.2021.574047, PubMed 34026769

Hermansen JU, Wojcik DM, Robinson N, Pahnke J, Haugland HK, Jamtøy AH, Flaegstad T, Halvorsen H, Lund B, Baumbusch LO, Munthe-Kaas MC (2021)
The Norwegian childhood cancer biobank
Cancer Rep (Hoboken), e1555
DOI 10.1002/cnr2.1555, PubMed 34541832

Holmsen ST, Lona AM, Solberg R (2021)
Correct treatment for tongue-tie in infants
Tidsskr Nor Laegeforen, 141
DOI 10.4045/tidsskr.21.0520, PubMed 34597007

Jarvis KB, Andersson NG, Giertz M, Järvelä L, Lindinger O, Långström S, Niinimäki R, Palmu S, Trakymiene SS, Tuckuviene R, Vepsäläinen K, Ranta S, Frisk T (2021)
Asymptomatic Right Atrial Thrombosis After Acute Lymphoblastic Leukemia Treatment
J Pediatr Hematol Oncol, 43 (4), e564-e566
DOI 10.1097/MPH.0000000000001848, PubMed 32555028

Kapadia V, Oei JL, Finer N, Rich W, Rabi Y, Wright IM, Rook D, Vermeulen MJ, Tarnow-Mordi WO, Smyth JP, Lui K, Brown S, Saugstad OD, Vento M (2021)
Outcomes of delivery room resuscitation of bradycardic preterm infants: A retrospective cohort study of randomised trials of high vs low initial oxygen concentration and an individual patient data analysis
Resuscitation, 167, 209-217
DOI 10.1016/j.resuscitation.2021.08.023, PubMed 34425156

Kaustio M, Nayebzadeh N, Hinttala R, Tapiainen T, Åström P, Mamia K, Pernaa N, Lehtonen J, Glumoff V, Rahikkala E, Honkila M, Olsén P, Hassinen A, Polso M, Al Sukaiti N, Al Shekaili J, Al Kindi M, Al Hashmi N, Almusa H, Bulanova D, Haapaniemi E, Chen P, Suo-Palosaari M, Vieira P, Tuominen H et al. (2021)
Loss of DIAPH1 causes SCBMS, combined immunodeficiency, and mitochondrial dysfunction
J Allergy Clin Immunol, 148 (2), 599-611
DOI 10.1016/j.jaci.2020.12.656, PubMed 33662367

Kim J, Sullivan GJ, Park IH (2021)
How well do brain organoids capture your brain?
iScience, 24 (2), 102063
DOI 10.1016/j.isci.2021.102063, PubMed 33554067

Kristensen VA, Opheim R, Perminow G, Huppertz-Hauss G, Detlie TE, Lund C, Andersen S, Olsen BC, Johansen I, Medhus AW, Vatn S, Brackmann S, Olbjørn C, Rove J, Henriksen M, Løvlund EE, Bengtson MB, Aabrekk TB, Tønnessen T, Vikskjold FB, Yassin H, Frigstad SO, Hasund A, Høie O, Schmidt K et al. (2021)
Inflammatory bowel disease in South-Eastern Norway III (IBSEN III): a new population-based inception cohort study from South-Eastern Norway
Scand J Gastroenterol, 56 (8), 899-905
DOI 10.1080/00365521.2021.1922746, PubMed 34154494

Odland HH, Holm T, Gammelsrud LO, Cornelussen R, Kongsgaard E (2021)
Determinants of LV dP/dtmax and QRS duration with different fusion strategies in cardiac resynchronisation therapy
Open Heart, 8 (1)
DOI 10.1136/openhrt-2021-001615, PubMed 33963078

Odland HH, Villegas-Martinez M, Ross S, Holm T, Cornelussen R, Remme EW, Kongsgard E (2021)
Shortening of time-to-peak left ventricular pressure rise (Td) in cardiac resynchronization therapy
ESC Heart Fail
DOI 10.1002/ehf2.13601, PubMed 34514746

Oikarinen S, Krogvold L, Edwin B, Buanes T, Korsgren O, Laiho JE, Oikarinen M, Ludvigsson J, Skog O, Anagandula M, Frisk G, Hyöty H, Dahl-Jørgensen K (2021)
Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study
Diabetologia, 64 (11), 2491-2501
DOI 10.1007/s00125-021-05525-0, PubMed 34390364

Popperud TH, Gul KA, Brunborg C, Olaussen RW, Abrahamsen TG, Osnes LT, Kerty E (2021)
Thymectomy in Juvenile Myasthenia Gravis Is Safe Regarding Long Term Immunological Effects
Front Neurol, 12, 596859
DOI 10.3389/fneur.2021.596859, PubMed 33716918

Schultz NH, Glosli H, Bjørnsen S, Holme PA (2021)
The effect of emicizumab and bypassing agents in patients with hemophilia - An in vitro study
Res Pract Thromb Haemost, 5 (5), e12561
DOI 10.1002/rth2.12561, PubMed 34263107

Sever D, Hershko-Moshe A, Srivastava R, Eldor R, Hibsher D, Keren-Shaul H, Amit I, Bertuzzi F, Krogvold L, Dahl-Jørgensen K, Ben-Dov IZ, Landsman L, Melloul D (2021)
NF-κB activity during pancreas development regulates adult β-cell mass by modulating neonatal β-cell proliferation and apoptosis
Cell Death Discov, 7 (1), 2
DOI 10.1038/s41420-020-00386-9, PubMed 33414444

Skottvoll FS, Hansen FA, Harrison S, Boger IS, Mrsa A, Restan MS, Stein M, Lundanes E, Pedersen-Bjergaard S, Aizenshtadt A, Krauss S, Sullivan G, Bogen IL, Wilson SR (2021)
Electromembrane Extraction and Mass Spectrometry for Liver Organoid Drug Metabolism Studies
Anal Chem, 93 (7), 3576-3585
DOI 10.1021/acs.analchem.0c05082, PubMed 33534551

Spijkers S, Littooij AS, Kwee TC, Tolboom N, Beishuizen A, Bruin MCA, Enríquez G, Sábado C, Miller E, Granata C, de Lange C, Verzegnassi F, de Keizer B, Nievelstein RAJ (2021)
Whole-body MRI versus an [18F]FDG-PET/CT-based reference standard for early response assessment and restaging of paediatric Hodgkin's lymphoma: a prospective multicentre study
Eur Radiol
DOI 10.1007/s00330-021-08026-1, PubMed 34021390

Tapia G, Chudá K, Kahrs CR, Stene LC, Kramna L, Mårild K, Rasmussen T, Rønningen KS, Cinek O, Størdal K (2021)
Parechovirus Infection in Early Childhood and Association With Subsequent Celiac Disease
Am J Gastroenterol, 116 (4), 788-795
DOI 10.14309/ajg.0000000000001003, PubMed 33982949

Tapia G, Suvitaival T, Ahonen L, Lund-Blix NA, Njølstad PR, Joner G, Skrivarhaug T, Legido-Quigley C, Størdal K, Stene LC (2021)
Prediction of Type 1 Diabetes at Birth: Cord Blood Metabolites vs Genetic Risk Score in the Norwegian Mother, Father, and Child Cohort
J Clin Endocrinol Metab, 106 (10), e4062-e4071
DOI 10.1210/clinem/dgab400, PubMed 34086903

Thastrup M, Marquart HV, Levinsen M, Modvig S, Abrahamsson J, Albertsen BK, Frost BM, Harila-Saari A, Pesola J, Ulvmoen A, Wojcik DM, Taskinen M, Hoffmann M, Lausen B, Schmiegelow K, Nordic Society of Paediatric Haematology, Oncology (NOPHO) (2021)
Flow cytometric analysis of cerebrospinal fluid improves detection of leukaemic blasts in infants with acute lymphoblastic leukaemia
Br J Haematol, 195 (1), 119-122
DOI 10.1111/bjh.17769, PubMed 34396501

Thrane KJ, Müller LSO, Suther KR, Thomassen KS, Holmström H, Thaulow E, Almaas R, Möller T, de Lange C (2021)
Spectrum of Fontan-associated liver disease assessed by MRI and US in young adolescents
Abdom Radiol (NY), 46 (7), 3205-3216
DOI 10.1007/s00261-021-02994-0, PubMed 33688987

Toussaint M, Chatwin M, Gonçalves MR, Gonzalez-Bermejo J, Benditt JO, McKim D, Sancho J, Hov B, Sansone V, Prigent H, Carlucci A, Wijkstra P, Garabelli B, Escarrabill J, Pinto T, Audag N, Verweij-van den Oudenrijn L, Ogna A, Hughes W, Devaux C, Chaulet J, Andersen T, ENMC Respiratory Therapy Consortium (2021)
Mouthpiece ventilation in neuromuscular disorders: Narrative review of technical issues important for clinical success
Respir Med, 180, 106373
DOI 10.1016/j.rmed.2021.106373, PubMed 33798870

 
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