Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2020 from OUS - Section of Endocrinology
86 publications found
Gastric bypass surgery is associated with reduced subclinical myocardial injury and greater activation of the cardiac natriuretic peptide system than lifestyle intervention
Clin Biochem, 86, 36-44
DOI 10.1016/j.clinbiochem.2020.09.006, PubMed 32986994
High Body Mass Index and Central Adiposity Is Associated with Increased Risk of Acute Pancreatitis: A Meta-Analysis
Dig Dis Sci
DOI 10.1007/s10620-020-06275-6, PubMed 32556971
Diabetes mellitus and the risk of pancreatitis: A systematic review and meta-analysis of cohort studies
Pancreatology, 20 (4), 602-607
DOI 10.1016/j.pan.2020.03.019, PubMed 32409279
Physical activity and the risk of sudden cardiac death: a systematic review and meta-analysis of prospective studies
BMC Cardiovasc Disord, 20 (1), 318
DOI 10.1186/s12872-020-01531-z, PubMed 32631241
Physical activity and the risk of heart failure: a systematic review and dose-response meta-analysis of prospective studies
Eur J Epidemiol
DOI 10.1007/s10654-020-00693-6, PubMed 33331992
Physical activity and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies
Sci Rep, 10 (1), 22287
DOI 10.1038/s41598-020-76306-9, PubMed 33339835
Lower cardiorenal risk with sodium-glucose cotransporter-2 inhibitors versus dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes without cardiovascular and renal diseases: A large multinational observational study
Diabetes Obes Metab, 23 (1), 75-85
DOI 10.1111/dom.14189, PubMed 32893440
Heart failure and chronic kidney disease manifestation and mortality risk associations in type 2 diabetes: A large multinational cohort study
Diabetes Obes Metab, 22 (9), 1607-1618
DOI 10.1111/dom.14074, PubMed 32363737
Auto regulatory capacity of the thyroid gland after numerous iodinated contrast media investigations
Scand J Clin Lab Invest, 80 (3), 191-195
DOI 10.1080/00365513.2019.1709658, PubMed 31990217
Cardiovascular consequences of parathyroid disorders in adults
Ann Endocrinol (Paris) (in press)
DOI 10.1016/j.ando.2020.02.003, PubMed 32192790
Vitamin D metabolites influence expression of genes concerning cellular viability and function in insulin producing β-cells (INS1E)
Gene, 746, 144649
DOI 10.1016/j.gene.2020.144649, PubMed 32251702
Corticotroph aggressive pituitary tumours and carcinomas frequently harbour ATRX mutations
J Clin Endocrinol Metab (in press)
DOI 10.1210/clinem/dgaa749, PubMed 33106857
Health benefits and risks during 10 years after Roux-en-Y gastric bypass
Surg Endosc, 34 (12), 5368-5376
DOI 10.1007/s00464-019-07328-2, PubMed 31993812
A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity: results from a large European cohort
Sci Rep, 10 (1), 14541
DOI 10.1038/s41598-020-71302-5, PubMed 32883969
Associations between dietary patterns and gene expression pattern in peripheral blood mononuclear cells: A cross-sectional study
Nutr Metab Cardiovasc Dis, 30 (11), 2111-2122
DOI 10.1016/j.numecd.2020.06.018, PubMed 32807640
Neutrophil to lymphocyte ratio and cancer prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies
BMC Med, 18 (1), 360
DOI 10.1186/s12916-020-01817-1, PubMed 33213430
Lower Serum Estradiol Levels in Assigned Female at Birth Transgender People with Initiation of Testosterone Therapy: Results from the European Network for the Investigation of Gender Incongruence
LGBT Health, 7 (2), 71-81
DOI 10.1089/lgbt.2019.0260, PubMed 32049583
Vaginal bleeding and spotting in transgender men after initiation of testosterone therapy: A prospective cohort study (ENIGI)
Int J Transgend Health, 21 (2), 163-175
DOI 10.1080/26895269.2020.1719951, PubMed 32935087
Unilateral acute anterior uveitis is associated with ipsilateral changes in the tear fluid proteome that involves the LXR/RXR pathway
J Ophthalmic Inflamm Infect, 10 (1), 13
DOI 10.1186/s12348-020-00204-4, PubMed 32458144
Distinct Pattern of Endoplasmic Reticulum Protein Processing and Extracellular Matrix Proteins in Functioning and Silent Corticotroph Pituitary Adenomas
Cancers (Basel), 12 (10)
DOI 10.3390/cancers12102980, PubMed 33066652
Effects of Acute Exercise on Drug Craving, Self-Esteem, Mood, and Affect in Adults with Polysubstance Use Disorder: Protocol for a Multicenter Randomized Controlled Trial
JMIR Res Protoc, 9 (10), e18553
DOI 10.2196/18553, PubMed 33048056
Diagnosis and Treatment of Parasellar Lesions
Neuroendocrinology, 110 (9-10), 728-739
DOI 10.1159/000506905, PubMed 32126547
ENDOCRINOLOGY IN THE TIME OF COVID-19: Management of calcium metabolic disorders and osteoporosis
Eur J Endocrinol, 183 (2), G57-G65
DOI 10.1530/EJE-20-0385, PubMed 32396134
Stroke Prevention With the PCSK9 (Proprotein Convertase Subtilisin-Kexin Type 9) Inhibitor Evolocumab Added to Statin in High-Risk Patients With Stable Atherosclerosis
Stroke, 51 (5), 1546-1554
DOI 10.1161/STROKEAHA.119.027759, PubMed 32312223
Consensus statement from 2nd International Conference on Controversies in Vitamin D
Rev Endocr Metab Disord, 21 (1), 89-116
DOI 10.1007/s11154-019-09532-w, PubMed 32180081
Controversies in Vitamin D: A Statement From the Third International Conference
JBMR Plus, 4 (12), e10417
DOI 10.1002/jbm4.10417, PubMed 33354643
Substantial inter-individual variations in insulin secretion and sensitivity across the glucometabolic spectrum
Scand J Clin Lab Invest, 80 (4), 282-290
DOI 10.1080/00365513.2020.1730433, PubMed 32134347
High prevalence of ADHD symptoms in unmedicated youths with post-H1N1 narcolepsy type 1
Sleep Med, 75, 171-180
DOI 10.1016/j.sleep.2020.06.014, PubMed 32858357
Relationships Between Vitamin D Status and PTH over 5 Years After Roux-en-Y Gastric Bypass: a Longitudinal Cohort Study
Obes Surg, 30 (9), 3426-3434
DOI 10.1007/s11695-020-04582-5, PubMed 32306297
Assessing Periprosthetic Bone in Total Wrist Arthroplasty: The Validity of DXA
J Clin Densitom (in press)
DOI 10.1016/j.jocd.2020.10.006, PubMed 33172804
Collagen methionine sulfoxide and glucuronidine/LW-1 are markers of coronary artery disease in long-term survivors with type 1 diabetes. The Dialong study
PLoS One, 15 (5), e0233174
DOI 10.1371/journal.pone.0233174, PubMed 32401813
Replacement of Red and Processed Meat With Other Food Sources of Protein and the Risk of Type 2 Diabetes in European Populations: The EPIC-InterAct Study
Diabetes Care, 43 (11), 2660-2667
DOI 10.2337/dc20-1038, PubMed 32868270
Vitamin D status and complications, readmissions, and mortality after hip fracture
Osteoporos Int
DOI 10.1007/s00198-020-05739-9, PubMed 33201249
Liver nucleotide biosynthesis is linked to protection from vascular complications in individuals with long-term type 1 diabetes
Sci Rep, 10 (1), 11561
DOI 10.1038/s41598-020-68130-y, PubMed 32665614
The Value of Macular Optical Coherence Tomography in Watchful Waiting of Suprasellar Masses: A 2-Year Observational Study
J Neuroophthalmol (in press)
DOI 10.1097/WNO.0000000000000993, PubMed 33252889
HLA and sleep parameter associations in post-H1N1 narcolepsy type 1 patients and first-degree relatives
Sleep, 43 (3)
DOI 10.1093/sleep/zsz239, PubMed 31606740
Vitamin D Metabolites and Binding Protein Predict Preeclampsia in Women with Type 1 Diabetes
Nutrients, 12 (7)
DOI 10.3390/nu12072048, PubMed 32664257
The challenge of implementing Less is More medicine: A European perspective
Eur J Intern Med, 76, 1-7
DOI 10.1016/j.ejim.2020.04.014, PubMed 32303454
Tea Consumption and Risk of Cancer: An Umbrella Review and Meta-Analysis of Observational Studies
Adv Nutr, 11 (6), 1437-1452
DOI 10.1093/advances/nmaa077, PubMed 32667980
Risk factor management of type 2 diabetic patients in primary care in the Scandinavian countries between 2003 and 2015
Prim Care Diabetes (in press)
DOI 10.1016/j.pcd.2020.09.006, PubMed 33032936
Risk of cardiovascular events and death associated with initiation of SGLT2 inhibitors compared with DPP-4 inhibitors: an analysis from the CVD-REAL 2 multinational cohort study
Lancet Diabetes Endocrinol, 8 (7), 606-615
DOI 10.1016/S2213-8587(20)30130-3, PubMed 32559476
Cut-off values for sufficient cortisol response to low dose Short Synacthen Test after surgery for non-functioning pituitary adenoma
Acta Neurochir (Wien), 162 (4), 845-852
DOI 10.1007/s00701-019-04068-z, PubMed 31907611
FSH Levels Are Related to E-cadherin Expression and Subcellular Location in Nonfunctioning Pituitary Tumors
J Clin Endocrinol Metab, 105 (8)
DOI 10.1210/clinem/dgaa281, PubMed 32421791
Bone mineral density and vitamin D in paediatric intestinal failure patients receiving home parenteral nutrition
Clin Nutr ESPEN, 39, 234-241
DOI 10.1016/j.clnesp.2020.06.006, PubMed 32859323
Blood-based epigenetic estimators of chronological age in human adults using DNA methylation data from the Illumina MethylationEPIC array
BMC Genomics, 21 (1), 747
DOI 10.1186/s12864-020-07168-8, PubMed 33109080
25-Hydroxyvitamin D status, vitamin D intake, and skin cancer risk: a systematic review and dose-response meta-analysis of prospective studies
Sci Rep, 10 (1), 13151
DOI 10.1038/s41598-020-70078-y, PubMed 32753685
Investigating the causal effect of maternal vitamin B12 and folate levels on offspring birthweight
Int J Epidemiol (in press)
DOI 10.1093/ije/dyaa256, PubMed 33347560
Effects of modified Atkins diet on thyroid function in adult patients with pharmacoresistant epilepsy
Epilepsy Behav, 111, 107285
DOI 10.1016/j.yebeh.2020.107285, PubMed 32698106
Higher levels of bodily pain in people with long-term type 1 diabetes: associations with quality of life, depressive symptoms, fatigue and glycaemic control - the Dialong study
Diabet Med, 37 (9), 1569-1577
DOI 10.1111/dme.14331, PubMed 32446279
Healthy lifestyle and the risk of lymphoma in the European Prospective Investigation into Cancer and Nutrition study
Int J Cancer, 147 (6), 1649-1656
DOI 10.1002/ijc.32977, PubMed 32176325
Association between employment status and risk of all-cause and cause-specific mortality: a population-based prospective cohort study
J Epidemiol Community Health, 74 (5), 428-436
DOI 10.1136/jech-2019-213179, PubMed 32086372
Variation between general practitioners in type 2 diabetes processes of care
Prim Care Diabetes (in press)
DOI 10.1016/j.pcd.2020.11.018, PubMed 33349599
Obesity and other medical comorbidities among NT1 patients after the Norwegian H1N1 influenza epidemic and vaccination campaign
Sleep, 43 (5)
DOI 10.1093/sleep/zsz277, PubMed 31724727
Lecithin:cholesterol acyltransferase: symposium on 50 years of biomedical research from its discovery to latest findings
J Lipid Res, 61 (8), 1142-1149
DOI 10.1194/jlr.S120000720, PubMed 32482717
Underlying conditions in adults with COVID-19
Tidsskr Nor Laegeforen, 140 (13)
DOI 10.4045/tidsskr.20.0512, PubMed 32998491
Adiposity and the risk of rheumatoid arthritis: a systematic review and meta-analysis of cohort studies
Sci Rep, 10 (1), 16006
DOI 10.1038/s41598-020-71676-6, PubMed 32994434
Effects of dietary methionine and cysteine restriction on plasma biomarkers, serum fibroblast growth factor 21, and adipose tissue gene expression in women with overweight or obesity: a double-blind randomized controlled pilot study
J Transl Med, 18 (1), 122
DOI 10.1186/s12967-020-02288-x, PubMed 32160926
Epigenetic signatures associated with maternal body mass index or gestational weight gain: a systematic review
J Dev Orig Health Dis, 1-11 (in press)
DOI 10.1017/S2040174420000811, PubMed 32873364
Effects of Parathyroidectomy on Quality of Life: 10 Years of Data From a Prospective Randomized Controlled Trial on Primary Hyperparathyroidism (the SIPH-Study)
J Bone Miner Res, 36 (1), 3-11
DOI 10.1002/jbmr.4199, PubMed 33125769
Reducing the Clinical and Public Health Burden of Familial Hypercholesterolemia: A Global Call to Action
JAMA Cardiol, 5 (2), 217-229
DOI 10.1001/jamacardio.2019.5173, PubMed 31895433
Changes in maternal blood glucose and lipid concentrations during pregnancy differ by maternal body mass index and are related to birthweight: A prospective, longitudinal study of healthy pregnancies
PLoS One, 15 (6), e0232749
DOI 10.1371/journal.pone.0232749, PubMed 32574162
Cardiovascular and skeletal safety of zoledronic acid in osteoporosis observational, matched cohort study using Danish and Swedish health registries
Bone, 134, 115296
DOI 10.1016/j.bone.2020.115296, PubMed 32097760
Intake of Fermented Dairy Products Induces a Less Pro-Inflammatory Postprandial Peripheral Blood Mononuclear Cell Gene Expression Response than Non-Fermented Dairy Products: A Randomized Controlled Cross-Over Trial
Mol Nutr Food Res, 64 (21), e2000319
DOI 10.1002/mnfr.202000319, PubMed 32844586
Mediating effect of soluble B-cell activation immune markers on the association between anthropometric and lifestyle factors and lymphoma development
Sci Rep, 10 (1), 13814
DOI 10.1038/s41598-020-70790-9, PubMed 32796953
Residual Corticosteroid Production in Autoimmune Addison Disease
J Clin Endocrinol Metab, 105 (7)
DOI 10.1210/clinem/dgaa256, PubMed 32392298
Content and system development of a digital patient-provider communication tool to support shared decision making in chronic health care: InvolveMe
BMC Med Inform Decis Mak, 20 (1), 46
DOI 10.1186/s12911-020-1065-8, PubMed 32131808
Circulating bilirubin levels and risk of colorectal cancer: serological and Mendelian randomization analyses
BMC Med, 18 (1), 229
DOI 10.1186/s12916-020-01703-w, PubMed 32878631
TGFBR3L-An Uncharacterised Pituitary Specific Membrane Protein Detected in the Gonadotroph Cells in Non-Neoplastic and Tumour Tissue
Cancers (Basel), 13 (1)
DOI 10.3390/cancers13010114, PubMed 33396509
The total prevalence of diagnosed diabetes and the quality of diabetes care for the adult population in Salten, Norway
Scand J Public Health, 1403494820951004
DOI 10.1177/1403494820951004, PubMed 32854596
Prediagnostic serum 25-hydroxyvitamin D and melanoma risk
Sci Rep, 10 (1), 20129
DOI 10.1038/s41598-020-77155-2, PubMed 33208828
Factors mediating the pressor response to isometric muscle contraction: An experimental study in healthy volunteers during lower body negative pressure
PLoS One, 15 (12), e0243627
DOI 10.1371/journal.pone.0243627, PubMed 33296410
Evaluating the use of the heart age tool in community pharmacies: a 4-week cluster-randomized controlled trial
Eur J Public Health, 30 (6), 1139-1145
DOI 10.1093/eurpub/ckaa048, PubMed 32206810
Genetic testing is essential for initiating statin therapy in children with familial hypercholesterolemia: Examples from Scandinavia
Atherosclerosis, 316, 48-52
DOI 10.1016/j.atherosclerosis.2020.11.027, PubMed 33302044
Fatty acid profile and estimated desaturase activities in whole blood are associated with metabolic health
Lipids Health Dis, 19 (1), 102
DOI 10.1186/s12944-020-01282-y, PubMed 32438926
Electrolyte outpatient clinic at a local hospital - experience from diagnostics, treatment and follow-up
BMC Health Serv Res, 20 (1), 154
DOI 10.1186/s12913-020-5022-0, PubMed 32111205
Availability and analytical quality of hemoglobin A1c point-of-care testing in general practitioners' offices are associated with better glycemic control in type 2 diabetes
Clin Chem Lab Med, 58 (8), 1349-1356
DOI 10.1515/cclm-2020-0026, PubMed 32229656
The associations of major foods and fibre with risks of ischaemic and haemorrhagic stroke: a prospective study of 418 329 participants in the EPIC cohort across nine European countries
Eur Heart J, 41 (28), 2632-2640
DOI 10.1093/eurheartj/ehaa007, PubMed 32090257
Factors associated with potential over- and undertreatment of hyperglycaemia and annual measurement of HbA1c in type 2 diabetes in norwegian general practice
Diabet Med, e14500
DOI 10.1111/dme.14500, PubMed 33354827
Elevated levels of the secreted wingless agonist R-spondin 3 in preeclamptic pregnancies
J Hypertens, 38 (7), 1347-1354
DOI 10.1097/HJH.0000000000002362, PubMed 31990902
Elevated Cholesteryl Ester Transfer Protein Activity Early in Pregnancy Predicts Prediabetes 5 Years Later
J Clin Endocrinol Metab, 105 (3)
DOI 10.1210/clinem/dgz119, PubMed 31665383
Metabolomic and gene expression analysis to study the effects of dietary saturated and polyunsaturated fats
Curr Opin Lipidol, 31 (1), 15-19
DOI 10.1097/MOL.0000000000000651, PubMed 31789669
Association between sleep duration and mortality risk among adults with type 2 diabetes: a prospective cohort study
Diabetologia, 63 (11), 2292-2304
DOI 10.1007/s00125-020-05214-4, PubMed 32671413
Upregulation of HLA Class I and Antiviral Tissue Responses in Hashimoto's Thyroiditis
Thyroid, 30 (3), 432-442
DOI 10.1089/thy.2019.0607, PubMed 31910110
Dietary and Circulating Fatty Acids and Ovarian Cancer Risk in the European Prospective Investigation into Cancer and Nutrition
Cancer Epidemiol Biomarkers Prev, 29 (9), 1739-1749
DOI 10.1158/1055-9965.EPI-19-1477, PubMed 32616494
Blood polyphenol concentrations and differentiated thyroid carcinoma in women from the European Prospective Investigation into Cancer and Nutrition (EPIC) study
Am J Clin Nutr, 113 (1), 162-171
DOI 10.1093/ajcn/nqaa277, PubMed 33021645
Association of plasma biomarkers of fruit and vegetable intake with incident type 2 diabetes: EPIC-InterAct case-cohort study in eight European countries
BMJ, 370, m2194
DOI 10.1136/bmj.m2194, PubMed 32641421