Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2021 from OUS - Section of Preventive Medicine

22 publications found

Arnesen KE, Phung AV, Randsborg K, Mork I, Thorvall M, Langslet G, Svilaas A, Wium C, Ose L, Retterstol K (2021)
Risk of Recurrent Coronary Events in Patients With Familial Hypercholesterolemia; A 10-Years Prospective Study
Front. Pharmacol., 11, 560958

Bergum H, Sandven I, Klemsdal TO (2021)
Long-term effects (> 24 months) of multiple lifestyle intervention on major cardiovascular risk factors among high-risk subjects: a meta-analysis
BMC Cardiovasc Disord, 21 (1), 181
DOI 10.1186/s12872-021-01989-5, PubMed 33858345

Deedwania P, Murphy SA, Scheen A, Badariene J, Pineda AL, Honarpour N, Keech AC, Sever PS, Pedersen TR, Sabatine MS, Giugliano RP (2021)
Efficacy and Safety of PCSK9 Inhibition With Evolocumab in Reducing Cardiovascular Events in Patients With Metabolic Syndrome Receiving Statin Therapy: Secondary Analysis From the FOURIER Randomized Clinical Trial
JAMA Cardiol, 6 (2), 139-147
DOI 10.1001/jamacardio.2020.3151, PubMed 32785614

Hustad KS, Ottestad I, Hjorth M, Dalen KT, Sæther T, Sheikh NA, Strømnes M, Ulven SM, Holven KB (2021)
No effect of salmon fish protein on 2-h glucose in adults with increased risk of type 2 diabetes: a randomised controlled trial
Br J Nutr, 1-10 (in press)
DOI 10.1017/S0007114521000040, PubMed 33413727

Johannessen TR, Atar D, Vallersnes OM, Larstorp ACK, Mdala I, Halvorsen S (2021)
Comparison of a single high-sensitivity cardiac troponin T measurement with the HEART score for rapid rule-out of acute myocardial infarction in a primary care emergency setting: a cohort study
BMJ Open, 11 (2), e046024
DOI 10.1136/bmjopen-2020-046024, PubMed 33627355

Johansen AK, Bogsrud MP, Roeters van Lennep J, Narverud I, Langslet G, Retterstøl K, Holven KB (2021)
Long term follow-up of children with familial hypercholesterolemia and relatively normal LDL-cholesterol at diagnosis
J Clin Lipidol (in press)
DOI 10.1016/j.jacl.2021.01.007, PubMed 33608220

Keech AC, Oyama K, Sever PS, Tang M, Murphy SA, Hirayama A, Lu C, Tay L, Deedwania PC, Siu CW, Lira Pineda A, Choi D, Charng MJ, Amerena J, Wan Ahmad WA, Chopra VK, Pedersen TR, Giugliano RP, Sabatine MS, FOURIER Study Group (2021)
Efficacy and Safety of Long-Term Evolocumab Use Among Asian Subjects - A Subgroup Analysis of the Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk (FOURIER) Trial
Circ J (in press)
DOI 10.1253/circj.CJ-20-1051, PubMed 33980763

Lie ØH, Chivulescu M, Rootwelt-Norberg C, Ribe M, Bogsrud MP, Lyseggen E, Beitnes JO, Almaas V, Haugaa KH (2021)
Left Ventricular Dysfunction in Arrhythmogenic Cardiomyopathy: Association With Exercise Exposure, Genetic Basis, and Prognosis
J Am Heart Assoc, 10 (8), e018680
DOI 10.1161/JAHA.120.018680, PubMed 33821670

Olsen E, Holzhauer B, Julius S, Kjeldsen SE, Larstorp ACK, Mancia G, Mehlum MH, Mo R, Rostrup M, Søraas CL, Zappe D, Weber MA (2021)
Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus and hypertension
Blood Press, 30 (2), 82-89
DOI 10.1080/08037051.2020.1855968, PubMed 33403886

Olsen E, Holzhauer B, Julius S, Kjeldsen SE, Larstorp ACK, Mancia G, Mehlum MH, Mo R, Rostrup M, Søraas CL, Zappe D, Weber MA (2021)
Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus compared to all middle-aged and elderly hypertensive study patients with high cardiovascular risk
Blood Press, 30 (2), 90-97
DOI 10.1080/08037051.2020.1856642, PubMed 33403890

Opstad TB, Sundfør T, Tonstad S, Seljeflot I (2021)
Effect of intermittent and continuous caloric restriction on Sirtuin1 concentration depends on sex and body mass index
Nutr Metab Cardiovasc Dis (in press)
DOI 10.1016/j.numecd.2021.03.005, PubMed 33975734

Øyri LKL, Bogsrud MP, Christensen JJ, Ulven SM, Brantsæter AL, Retterstøl K, Brekke HK, Michelsen TM, Henriksen T, Roeters van Lennep JE, Magnus P, Veierød MB, Holven KB (2021)
Novel associations between parental and newborn cord blood metabolic profiles in the Norwegian Mother, Father and Child Cohort Study
BMC Med, 19 (1), 91
DOI 10.1186/s12916-021-01959-w, PubMed 33849542

Pope MK, Atar D, Svilaas A, Hole T, Nielsen JD, Hintze U, Crisby M, Raatikainen P, Airaksinen KEJ, Virdone S, Pieper K, Kayani G, Le Heuzey JY, Steffel J, Stepinska J, Bassand JP, Camm AJ, GARFIELD-AF Investigators (2021)
Risk profile, antithrombotic treatment and clinical outcomes of patients in Nordic countries with atrial fibrillation - results from the GARFIELD-AF registry
Ann Med, 53 (1), 485-494
DOI 10.1080/07853890.2021.1893897, PubMed 33818226

Retterstøl K, Munkhaugen J, Igul CB, Grimsmo J, Kask A, Schirmer H, Semb AG, Solberg EE (2021)
Retterstøl and colleagues respond
Tidsskr Nor Laegeforen, 141 (4)
DOI 10.4045/tidsskr.21.0122, PubMed 33685109

Retterstøl K, Munkhaugen J, Ingul CB, Grimsmo J, Kask A, Schirmer H, Semb AG, Solberg EE (2021)
Correction: Lower treatment goals for LDL cholesterol should be introduced
Tidsskr Nor Laegeforen, 141 (4)
DOI 10.4045/tidsskr.21.0096, PubMed 33685112

Retterstøl K, Munkhaugen J, Ingul CB, Grimsmo J, Kask A, Schirmer H, Semb AG, Solberg EE (2021)
Lower treatment goals for LDL cholesterol should be introduced
Tidsskr Nor Laegeforen, 141 (2)
DOI 10.4045/tidsskr.20.0761, PubMed 33528123

Rodríguez-Borjabad C, Narveud I, Christensen JJ, Ulven SM, Malo AI, Ibarretxe D, Girona J, Torvik K, Bogsrud MP, Retterstøl K, Plana N, Masana L, Holven KB (2021)
Dietary intake and lipid levels in Norwegian and Spanish children with familial hypercholesterolemia
Nutr Metab Cardiovasc Dis, 31 (4), 1299-1307
DOI 10.1016/j.numecd.2020.12.002, PubMed 33549456

Rognstad S, Søraas CL, Bergland OU, Høieggen A, Strømmen M, Helland A, Opdal MS (2021)
Establishing Serum Reference Ranges for Antihypertensive Drugs
Ther Drug Monit, 43 (1), 116-125
DOI 10.1097/FTD.0000000000000806, PubMed 32881780

Stolt E, Olsen T, Elshorbagy A, Kožich V, van Greevenbroek M, Øvrebø B, Thoresen M, Refsum H, Retterstøl K, Vinknes KJ (2021)
Sulfur amino acid restriction, energy metabolism and obesity: a study protocol of an 8-week randomized controlled dietary intervention with whole foods and amino acid supplements
J Transl Med, 19 (1), 153
DOI 10.1186/s12967-021-02824-3, PubMed 33858441

Undrum Bergland O, Larstorp ACK, Lund Søraas C, Høieggen A, Rostrup M, Norheim Kjaer V, Godang K, Sevre K, Fadl Elmula FEM (2021)
Changes in sympathetic nervous system activity after renal denervation: results from the randomised Oslo RDN study
Blood Press
DOI 10.1080/08037051.2020.1868286, PubMed 33399016

Vallejo-Vaz AJ, Packard CJ, Ference BA, Santos RD, Kastelein JJP, Stein EA, Catapano AL, Pedersen TR, Watts GF, Ray KK (2021)
LDL-cholesterol lowering and clinical outcomes in hypercholesterolemic subjects with and without a familial hypercholesterolemia phenotype: Analysis from the secondary prevention 4S trial
Atherosclerosis, 320, 1-9
DOI 10.1016/j.atherosclerosis.2021.01.003, PubMed 33497862

Zinöcker MK, Svendsen K, Dankel SN (2021)
The homeoviscous adaptation to dietary lipids (HADL) model explains controversies over saturated fat, cholesterol, and cardiovascular disease risk
Am J Clin Nutr, 113 (2), 277-289
DOI 10.1093/ajcn/nqaa322, PubMed 33471045

 
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