Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2021 from OUS - Section of Preventive Medicine

31 publications found

Arnesen KE, Phung AV, Randsborg K, Mork I, Thorvall M, Langslet G, Svilaas A, Wium C, Ose L, Retterstøl K (2021)
Risk of Recurrent Coronary Events in Patients With Familial Hypercholesterolemia; A 10-Years Prospective Study
Front Pharmacol, 11, 560958
DOI 10.3389/fphar.2020.560958, PubMed 33737874

Bergland OU, Halvorsen LV, Søraas CL, Hjørnholm U, Kjær VN, Rognstad S, Brobak KM, Aune A, Olsen E, Fauchald YM, Heimark S, Thorstensen CW, Liestøl K, Solbu MD, Gerdts E, Mo R, Rostrup M, Kjeldsen SE, Høieggen A, Opdal MS, Larstorp ACK, Fadl Elmula FEM (2021)
Detection of Nonadherence to Antihypertensive Treatment by Measurements of Serum Drug Concentrations
Hypertension, 78 (3), 617-628
DOI 10.1161/HYPERTENSIONAHA.121.17514, PubMed 34275336

Berglund I, Vesterbekkmo EK, Retterstøl K, Anderssen SA, Fiatarone Singh MA, Helge JW, Lydersen S, Wisløff U, Stensvold D (2021)
The Long-term Effect of Different Exercise Intensities on High-Density Lipoprotein Cholesterol in Older Men and Women Using the Per Protocol Approach: The Generation 100 Study
Mayo Clin Proc Innov Qual Outcomes, 5 (5), 859-871
DOI 10.1016/j.mayocpiqo.2021.07.002, PubMed 34585083

Bergum H, Sandven I, Klemsdal TO (2021)
Long-term effects (> 24 months) of multiple lifestyle intervention on major cardiovascular risk factors among high-risk subjects: a meta-analysis
BMC Cardiovasc Disord, 21 (1), 181
DOI 10.1186/s12872-021-01989-5, PubMed 33858345

Christensen JJ, Narverud I, Ruuth M, Heier M, Jauhiainen M, Ulven SM, Bogsrud MP, Kovanen PT, Halvorsen B, Oda MN, Wium C, Retterstøl K, Öörni K, Holven KB (2021)
Children with familial hypercholesterolemia display changes in LDL and HDL function: A cross-sectional study
J Intern Med, 290 (5), 1083-1097
DOI 10.1111/joim.13383, PubMed 34506681

Deedwania P, Murphy SA, Scheen A, Badariene J, Pineda AL, Honarpour N, Keech AC, Sever PS, Pedersen TR, Sabatine MS, Giugliano RP (2021)
Efficacy and Safety of PCSK9 Inhibition With Evolocumab in Reducing Cardiovascular Events in Patients With Metabolic Syndrome Receiving Statin Therapy: Secondary Analysis From the FOURIER Randomized Clinical Trial
JAMA Cardiol, 6 (2), 139-147
DOI 10.1001/jamacardio.2020.3151, PubMed 32785614

Falk RS, Mariampillai JE, Prestgaard EE, Heir T, Bodegård J, Robsahm TE, Grundvold I, Skretteberg PT, Engeseth K, Bjornholt JV, Stavem K, Liestøl K, Sandvik L, Thaulow E, Erikssen G, Kjeldsen SE, Gjesdal K, Erikssen JE (2021)
The Oslo Ischaemia Study: cohort profile
BMJ Open, 11 (10), e049111
DOI 10.1136/bmjopen-2021-049111, PubMed 34645662

Hustad KS, Ottestad I, Hjorth M, Dalen KT, Sæther T, Sheikh NA, Strømnes M, Ulven SM, Holven KB (2021)
No effect of salmon fish protein on 2-h glucose in adults with increased risk of type 2 diabetes: a randomised controlled trial
Br J Nutr, 126 (9), 1304-1313
DOI 10.1017/S0007114521000040, PubMed 33413727

Jakobsen J, Veierød MB, Grimsrud TK, Fosså SD, Hammarström B, Kjærheim K (2021)
Early detection of prostate cancer in firefighters: a register-based study of prognostic factors and survival
Occup Environ Med (in press)
DOI 10.1136/oemed-2021-107622, PubMed 34510005

Johannessen TR, Atar D, Vallersnes OM, Larstorp ACK, Mdala I, Halvorsen S (2021)
Comparison of a single high-sensitivity cardiac troponin T measurement with the HEART score for rapid rule-out of acute myocardial infarction in a primary care emergency setting: a cohort study
BMJ Open, 11 (2), e046024
DOI 10.1136/bmjopen-2020-046024, PubMed 33627355

Johansen AK, Bogsrud MP, Roeters van Lennep J, Narverud I, Langslet G, Retterstøl K, Holven KB (2021)
Long term follow-up of children with familial hypercholesterolemia and relatively normal LDL-cholesterol at diagnosis
J Clin Lipidol, 15 (2), 375-378
DOI 10.1016/j.jacl.2021.01.007, PubMed 33608220

Keech AC, Oyama K, Sever PS, Tang M, Murphy SA, Hirayama A, Lu C, Tay L, Deedwania PC, Siu CW, Lira Pineda A, Choi D, Charng MJ, Amerena J, Wan Ahmad WA, Chopra VK, Pedersen TR, Giugliano RP, Sabatine MS, FOURIER Study Group (2021)
Efficacy and Safety of Long-Term Evolocumab Use Among Asian Subjects - A Subgroup Analysis of the Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk (FOURIER) Trial
Circ J, 85 (11), 2063-2070
DOI 10.1253/circj.CJ-20-1051, PubMed 33980763

Klevmoen M, Bogsrud MP, Retterstøl K, Svilaas T, Vesterbekkmo EK, Hovland A, Berge C, Roeters van Lennep J, Holven KB (2021)
Loss of statin treatment years during pregnancy and breastfeeding periods in women with familial hypercholesterolemia
Atherosclerosis, 335, 8-15
DOI 10.1016/j.atherosclerosis.2021.09.003, PubMed 34520888

Langslet G, Johansen AK, Bogsrud MP, Narverud I, Risstad H, Retterstøl K, Holven KB (2021)
Thirty percent of children and young adults with familial hypercholesterolemia treated with statins have adherence issues
Am J Prev Cardiol, 6, 100180
DOI 10.1016/j.ajpc.2021.100180, PubMed 34327501

Lie ØH, Chivulescu M, Rootwelt-Norberg C, Ribe M, Bogsrud MP, Lyseggen E, Beitnes JO, Almaas V, Haugaa KH (2021)
Left Ventricular Dysfunction in Arrhythmogenic Cardiomyopathy: Association With Exercise Exposure, Genetic Basis, and Prognosis
J Am Heart Assoc, 10 (8), e018680
DOI 10.1161/JAHA.120.018680, PubMed 33821670

Olsen E, Holzhauer B, Julius S, Kjeldsen SE, Larstorp ACK, Mancia G, Mehlum MH, Mo R, Rostrup M, Søraas CL, Zappe D, Weber MA (2021)
Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus and hypertension
Blood Press, 30 (2), 82-89
DOI 10.1080/08037051.2020.1855968, PubMed 33403886

Olsen E, Holzhauer B, Julius S, Kjeldsen SE, Larstorp ACK, Mancia G, Mehlum MH, Mo R, Rostrup M, Søraas CL, Zappe D, Weber MA (2021)
Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus compared to all middle-aged and elderly hypertensive study patients with high cardiovascular risk
Blood Press, 30 (2), 90-97
DOI 10.1080/08037051.2020.1856642, PubMed 33403890

Øyri LKL, Bogsrud MP, Christensen JJ, Ulven SM, Brantsæter AL, Retterstøl K, Brekke HK, Michelsen TM, Henriksen T, Roeters van Lennep JE, Magnus P, Veierød MB, Holven KB (2021)
Novel associations between parental and newborn cord blood metabolic profiles in the Norwegian Mother, Father and Child Cohort Study
BMC Med, 19 (1), 91
DOI 10.1186/s12916-021-01959-w, PubMed 33849542

Øyri LKL, Bogsrud MP, Kristiansen AL, Myhre JB, Astrup H, Retterstøl K, Brekke HK, Roeters van Lennep JE, Andersen LF, Holven KB (2021)
Cholesterol at ages 6, 12 and 24 months: Tracking and associations with diet and maternal cholesterol in the Infant Cholesterol Study
Atherosclerosis, 326, 11-16
DOI 10.1016/j.atherosclerosis.2021.04.017, PubMed 33990045

Pope MK, Atar D, Svilaas A, Hole T, Nielsen JD, Hintze U, Crisby M, Raatikainen P, Airaksinen KEJ, Virdone S, Pieper K, Kayani G, Le Heuzey JY, Steffel J, Stepinska J, Bassand JP, Camm AJ, GARFIELD-AF Investigators (2021)
Risk profile, antithrombotic treatment and clinical outcomes of patients in Nordic countries with atrial fibrillation - results from the GARFIELD-AF registry
Ann Med, 53 (1), 485-494
DOI 10.1080/07853890.2021.1893897, PubMed 33818226

Rodríguez-Borjabad C, Narveud I, Christensen JJ, Ulven SM, Malo AI, Ibarretxe D, Girona J, Torvik K, Bogsrud MP, Retterstøl K, Plana N, Masana L, Holven KB (2021)
Dietary intake and lipid levels in Norwegian and Spanish children with familial hypercholesterolemia
Nutr Metab Cardiovasc Dis, 31 (4), 1299-1307
DOI 10.1016/j.numecd.2020.12.002, PubMed 33549456

Rognstad S, Søraas CL, Bergland OU, Høieggen A, Strømmen M, Helland A, Opdal MS (2021)
Establishing Serum Reference Ranges for Antihypertensive Drugs
Ther Drug Monit, 43 (1), 116-125
DOI 10.1097/FTD.0000000000000806, PubMed 32881780

Scholz JR, Abe TO, Gaya PV, Bellini B, de Moraes IRA, Santos JR, Tomaz PRX, de Lima Santos PC, Tonstad S (2021)
Cue restricted smoking increases quit rates with varenicline
Tob Prev Cessat, 7, 33
DOI 10.18332/tpc/133570, PubMed 34017927

Sever P, Gouni-Berthold I, Keech A, Giugliano R, Pedersen TR, Im K, Wang H, Knusel B, Sabatine MS, O'Donoghue ML (2021)
LDL-cholesterol lowering with evolocumab, and outcomes according to age and sex in patients in the FOURIER Trial
Eur J Prev Cardiol, 28 (8), 805-812
DOI 10.1177/2047487320902750, PubMed 34298555

Søraas A, Kalleberg KT, Dahl JA, Søraas CL, Myklebust TÅ, Axelsen E, Lind A, Bævre-Jensen R, Jørgensen SB, Istre MS, Kjetland EF, Ursin G (2021)
Persisting symptoms three to eight months after non-hospitalized COVID-19, a prospective cohort study
PLoS One, 16 (8), e0256142
DOI 10.1371/journal.pone.0256142, PubMed 34437579

Svendsen K, Torheim LE, Fjelberg V, Sorprud A, Narverud I, Retterstøl K, Bogsrud MP, Holven KB, Myhrstad MCW, Telle-Hansen VH (2021)
Gender differences in nutrition literacy levels among university students and employees: a descriptive study
J Nutr Sci, 10, e56
DOI 10.1017/jns.2021.47, PubMed 34367630

Undrum Bergland O, Larstorp ACK, Lund Søraas C, Høieggen A, Rostrup M, Norheim Kjaer V, Godang K, Sevre K, Fadl Elmula FEM (2021)
Changes in sympathetic nervous system activity after renal denervation: results from the randomised Oslo RDN study
Blood Press, 30 (3), 154-164
DOI 10.1080/08037051.2020.1868286, PubMed 33399016

Vallejo-Vaz AJ, Packard CJ, Ference BA, Santos RD, Kastelein JJP, Stein EA, Catapano AL, Pedersen TR, Watts GF, Ray KK (2021)
LDL-cholesterol lowering and clinical outcomes in hypercholesterolemic subjects with and without a familial hypercholesterolemia phenotype: Analysis from the secondary prevention 4S trial
Atherosclerosis, 320, 1-9
DOI 10.1016/j.atherosclerosis.2021.01.003, PubMed 33497862

Visseren FLJ, Mach F, Smulders YM, Carballo D, Koskinas KC, Bäck M, Benetos A, Biffi A, Boavida JM, Capodanno D, Cosyns B, Crawford C, Davos CH, Desormais I, Di Angelantonio E, Franco OH, Halvorsen S, Hobbs FDR, Hollander M, Jankowska EA, Michal M, Sacco S, Sattar N, Tokgozoglu L, Tonstad S et al. (2021)
2021 ESC Guidelines on cardiovascular disease prevention in clinical practice
Eur J Prev Cardiol (in press)
DOI 10.1093/eurjpc/zwab154, PubMed 34558602

Visseren FLJ, Mach F, Smulders YM, Carballo D, Koskinas KC, Bäck M, Benetos A, Biffi A, Boavida JM, Capodanno D, Cosyns B, Crawford C, Davos CH, Desormais I, Di Angelantonio E, Franco OH, Halvorsen S, Hobbs FDR, Hollander M, Jankowska EA, Michal M, Sacco S, Sattar N, Tokgozoglu L, Tonstad S et al. (2021)
2021 ESC Guidelines on cardiovascular disease prevention in clinical practice
Eur Heart J, 42 (34), 3227-3337
DOI 10.1093/eurheartj/ehab484, PubMed 34458905

Zinöcker MK, Svendsen K, Dankel SN (2021)
The homeoviscous adaptation to dietary lipids (HADL) model explains controversies over saturated fat, cholesterol, and cardiovascular disease risk
Am J Clin Nutr, 113 (2), 277-289
DOI 10.1093/ajcn/nqaa322, PubMed 33471045

 
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