Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2021 from OUS - Psychosis Research (NORMENT)

19 publications found

Akkouh IA, Hughes T, Steen VM, Glover JC, Andreassen OA, Djurovic S, Szabo A (2021)
Transcriptome analysis reveals disparate expression of inflammation-related miRNAs and their gene targets in iPSC-astrocytes from people with schizophrenia
Brain Behav Immun (in press)
DOI 10.1016/j.bbi.2021.01.037, PubMed 33571628

Bahrami S, Shadrin A, Frei O, O'Connell KS, Bettella F, Krull F, Fan CC, Røssberg JI, Hindley G, Ueland T, Dale AM, Djurovic S, Steen NE, Smeland OB, Andreassen OA (2021)
Genetic loci shared between major depression and intelligence with mixed directions of effect
Nat Hum Behav
DOI 10.1038/s41562-020-01031-2, PubMed 33462475

Barth C, Nerland S, de Lange AG, Wortinger LA, Hilland E, Andreassen OA, Jørgensen KN, Agartz I (2021)
In Vivo Amygdala Nuclei Volumes in Schizophrenia and Bipolar Disorders
Schizophr Bull (in press)
DOI 10.1093/schbul/sbaa192, PubMed 33479754

Dieset I, Løvhaug L, Selle M, Kolseth A, Smeland OB, Færden A (2021)
Lessons learned from a cross-sectional survey among patients and staff in an acute psychiatric unit during an ongoing pandemic outbreak
Psychiatry Res, 298, 113779 (in press)
DOI 10.1016/j.psychres.2021.113779, PubMed 33561619

Ditmars HL, Logue MW, Toomey R, McKenzie RE, Franz CE, Panizzon MS, Reynolds CA, Cuthbert KN, Vandiver R, Gustavson DE, Eglit GML, Elman JA, Sanderson-Cimino M, Williams ME, Andreassen OA, Dale AM, Eyler LT, Fennema-Notestine C, Gillespie NA, Hauger RL, Jak AJ, Neale MC, Tu XM, Whitsel N, Xian H et al. (2021)
Associations between depression and cardiometabolic health: A 27-year longitudinal study
Psychol Med, 1-11 (in press)
DOI 10.1017/S003329172000505X, PubMed 33431106

Hannigan LJ, Askeland RB, Ask H, Tesli M, Corfield E, Ayorech Z, Helgeland Ø, Magnus P, Njølstad PR, Øyen AS, Stoltenberg C, Andreassen OA, Davey Smith G, Reichborn-Kjennerud T, Havdahl A (2021)
Genetic Liability for Schizophrenia and Childhood Psychopathology in the General Population
Schizophr Bull (in press)
DOI 10.1093/schbul/sbaa193, PubMed 33561255

Hellstrøm T, Andelic N, de Lange AG, Helseth E, Eiklid K, Westlye LT (2021)
Apolipoprotein ɛ4 Status and Brain Structure 12 Months after Mild Traumatic Injury: Brain Age Prediction Using Brain Morphometry and Diffusion Tensor Imaging
J Clin Med, 10 (3)
DOI 10.3390/jcm10030418, PubMed 33499167

Huynh-Le MP, Fan CC, Karunamuni R, Thompson WK, Martinez ME, Eeles RA, Kote-Jarai Z, Muir K, Schleutker J, Pashayan N, Batra J, Grönberg H, Neal DE, Donovan JL, Hamdy FC, Martin RM, Nielsen SF, Nordestgaard BG, Wiklund F, Tangen CM, Giles GG, Wolk A, Albanes D, Travis RC, Blot WJ et al. (2021)
Polygenic hazard score is associated with prostate cancer in multi-ethnic populations
Nat Commun, 12 (1), 1236
DOI 10.1038/s41467-021-21287-0, PubMed 33623038

Karunamuni RA, Huynh-Le MP, Fan CC, Thompson W, Eeles RA, Kote-Jarai Z, Muir K, Lophatananon A, UKGPCS collaborators, Schleutker J, Pashayan N, Batra J, APCB BioResource (Australian Prostate Cancer BioResource), Grönberg H, Walsh EI, Turner EL, Lane A, Martin RM, Neal DE, Donovan JL, Hamdy FC, Nordestgaard BG, Tangen CM, MacInnis RJ, Wolk A et al. (2021)
Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer
Prostate Cancer Prostatic Dis
DOI 10.1038/s41391-020-00311-2, PubMed 33420416

Kessing LV, González-Pinto A, Fagiolini A, Bechdolf A, Reif A, Yildiz A, Etain B, Henry C, Severus E, Reininghaus EZ, Morken G, Goodwin GM, Scott J, Geddes JR, Rietschel M, Landén M, Manchia M, Bauer M, Martinez-Cengotitabengoa M, Andreassen OA, Ritter P, Kupka R, Licht RW, Nielsen RE, Schulze TG et al. (2021)
DSM-5 and ICD-11 criteria for bipolar disorder: Implications for the prevalence of bipolar disorder and validity of the diagnosis - A narrative review from the ECNP bipolar disorders network
Eur Neuropsychopharmacol (in press)
DOI 10.1016/j.euroneuro.2021.01.097, PubMed 33541809

Pogosbekian EL, Pronin IN, Zakharova NE, Batalov AI, Turkin AM, Konakova TA, Maximov II (2021)
Feasibility of generalised diffusion kurtosis imaging approach for brain glioma grading
Neuroradiology
DOI 10.1007/s00234-020-02613-7, PubMed 33410948

Radonjić NV, Hess JL, Rovira P, Andreassen O, Buitelaar JK, Ching CRK, Franke B, Hoogman M, Jahanshad N, McDonald C, Schmaal L, Sisodiya SM, Stein DJ, van den Heuvel OA, van Erp TGM, van Rooij D, Veltman DJ, Thompson P, Faraone SV (2021)
Structural brain imaging studies offer clues about the effects of the shared genetic etiology among neuropsychiatric disorders
Mol Psychiatry
DOI 10.1038/s41380-020-01002-z, PubMed 33456050

Reindal L, Nærland T, Weidle B, Lydersen S, Andreassen OA, Sund AM (2021)
Structural and Pragmatic Language Impairments in Children Evaluated for Autism Spectrum Disorder (ASD)
J Autism Dev Disord
DOI 10.1007/s10803-020-04853-1, PubMed 33515169

Reis de Assis D, Szabo A, Requena Osete J, Puppo F, O'Connell KS, A Akkouh I, Hughes T, Frei E, A Andreassen O, Djurovic S (2021)
Using iPSC Models to Understand the Role of Estrogen in Neuron-Glia Interactions in Schizophrenia and Bipolar Disorder
Cells, 10 (2)
DOI 10.3390/cells10020209, PubMed 33494281

Rødevand L, Bahrami S, Frei O, Lin A, Gani O, Shadrin A, Smeland OB, Connell KSO, Elvsåshagen T, Winterton A, Quintana DS, Hindley GFL, Werner MCF, Djurovic S, Dale AM, Lagerberg TV, Steen NE, Andreassen OA (2021)
Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms
Transl Psychiatry, 11 (1), 3
DOI 10.1038/s41398-020-01142-4, PubMed 33414458

Sønderby IE, Ching CRK, Thomopoulos SI, van der Meer D, Sun D, Villalon-Reina JE, Agartz I, Amunts K, Arango C, Armstrong NJ, Ayesa-Arriola R, Bakker G, Bassett AS, Boomsma DI, Bülow R, Butcher NJ, Calhoun VD, Caspers S, Chow EWC, Cichon S, Ciufolini S, Craig MC, Crespo-Facorro B, Cunningham AC, Dale AM et al. (2021)
Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs
Hum Brain Mapp (in press)
DOI 10.1002/hbm.25354, PubMed 33615640

van Dongen J, Hagenbeek FA, Suderman M, Roetman PJ, Sugden K, Chiocchetti AG, Ismail K, Mulder RH, Hafferty JD, Adams MJ, Walker RM, Morris SW, Lahti J, Küpers LK, Escaramis G, Alemany S, Jan Bonder M, Meijer M, Ip HF, Jansen R, Baselmans BML, Parmar P, Lowry E, Streit F, Sirignano L et al. (2021)
DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan
Mol Psychiatry (in press)
DOI 10.1038/s41380-020-00987-x, PubMed 33420481

Wisting L, Johnson SU, Bulik CM, Andreassen OA, Rø Ø, Bang L (2021)
Psychometric properties of the Norwegian version of the Patient Health Questionnaire-9 (PHQ-9) in a large female sample of adults with and without eating disorders
BMC Psychiatry, 21 (1), 6
DOI 10.1186/s12888-020-03013-0, PubMed 33402149

Wolfers T, Rokicki J, Alnaes D, Berthet P, Agartz I, Kia SM, Kaufmann T, Zabihi M, Moberget T, Melle I, Beckmann CF, Andreassen OA, Marquand AF, Westlye LT (2021)
Replicating extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder
Hum Brain Mapp (in press)
DOI 10.1002/hbm.25386, PubMed 33638594

 
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