Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2021 from OUS - Dept. of Microbiology, Lab for genome repair and regulation (Klungland)

10 publications found

Eriksson AM, Leikfoss IS, Abrahamsen G, Sundvold V, Isom MM, Keshari PK, Rognes T, Landsverk OJB, Bos SD, Harbo HF, Spurkland A, Berge T (2021)
Exploring the role of the multiple sclerosis susceptibility gene CLEC16A in T cells
Scand J Immunol, 94 (1), e13050
DOI 10.1111/sji.13050, PubMed 34643957

Jiang X, Bergquist A, Löscher BS, Venkatesh G, Mold JE, Holm K, Laerdahl JK, Skånland SS, Maleki KT, Cornillet M, Taskén K, Franke A, Karlsen TH, Björkström NK, Melum E (2021)
A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
Sci Transl Med, 13 (582)
DOI 10.1126/scitranslmed.abb0036, PubMed 33627483

Kværner AS, Birkeland E, Bucher-Johannessen C, Vinberg E, Nordby JI, Kangas H, Bemanian V, Ellonen P, Botteri E, Natvig E, Rognes T, Hovig E, Lyle R, Ambur OH, de Vos WM, Bultman S, Hjartåker A, Landberg R, Song M, Blix HS, Ursin G, Randel KR, de Lange T, Hoff G, Holme Ø et al. (2021)
The CRCbiome study: a large prospective cohort study examining the role of lifestyle and the gut microbiome in colorectal cancer screening participants
BMC Cancer, 21 (1), 930
DOI 10.1186/s12885-021-08640-8, PubMed 34407780

Mahé F, Czech L, Stamatakis A, Quince C, de Vargas C, Dunthorn M, Rognes T (2021)
Swarm v3: towards tera-scale amplicon clustering
Bioinformatics (in press)
DOI 10.1093/bioinformatics/btab493, PubMed 34244702

Parmar N, Burrows K, Vornewald PM, Lindholm HT, Zwiggelaar RT, Díez-Sánchez A, Martín-Alonso M, Fosslie M, Vallance BA, Dahl JA, Zaph C, Oudhoff MJ (2021)
Intestinal-epithelial LSD1 controls goblet cell maturation and effector responses required for gut immunity to bacterial and helminth infection
PLoS Pathog, 17 (3), e1009476
DOI 10.1371/journal.ppat.1009476, PubMed 33788902

Rasmussen EMK, Seier KL, Pedersen IK, Kreibich C, Amdam GV, Münch D, Dahl JA (2021)
Screening bioactive food compounds in honey bees suggests curcumin blocks alcohol-induced damage to longevity and DNA methylation
Sci Rep, 11 (1), 19156
DOI 10.1038/s41598-021-98614-4, PubMed 34580381

Sharma S, Mukherjee AK, Roy SS, Bagri S, Lier S, Verma M, Sengupta A, Kumar M, Nesse G, Pandey DP, Chowdhury S (2021)
Human telomerase is directly regulated by non-telomeric TRF2-G-quadruplex interaction
Cell Rep, 35 (7), 109154
DOI 10.1016/j.celrep.2021.109154, PubMed 34010660

Søraas A, Kalleberg KT, Dahl JA, Søraas CL, Myklebust TÅ, Axelsen E, Lind A, Bævre-Jensen R, Jørgensen SB, Istre MS, Kjetland EF, Ursin G (2021)
Persisting symptoms three to eight months after non-hospitalized COVID-19, a prospective cohort study
PLoS One, 16 (8), e0256142
DOI 10.1371/journal.pone.0256142, PubMed 34437579

Tesfahun AN, Alexeeva M, Tomkuvienė M, Arshad A, Guragain P, Klungland A, Klimašauskas S, Ruoff P, Bjelland S (2021)
Alleviation of C⋅C Mismatches in DNA by the Escherichia coli Fpg Protein
Front Microbiol, 12, 608839
DOI 10.3389/fmicb.2021.608839, PubMed 34276575

Zhang LS, Xiong QP, Peña Perez S, Liu C, Wei J, Le C, Zhang L, Harada BT, Dai Q, Feng X, Hao Z, Wang Y, Dong X, Hu L, Wang ED, Pan T, Klungland A, Liu RJ, He C (2021)
ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing
Nat Cell Biol, 23 (7), 684-691
DOI 10.1038/s41556-021-00709-7, PubMed 34253897

 
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