Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

Click here to see hierarchical division and subunit overview

Summary of publications:

Publications (original articles or review articles) published in 2021 from OUS - Department of Medical Biochemistry

37 publications found

Aksnes M, Aass HCD, Tiiman A, Edwin TH, Terenius L, Bogdanović N, Vukojević V, Knapskog AB (2021)
Associations of cerebrospinal fluid amyloidogenic nanoplaques with cytokines in Alzheimer's disease
Transl Neurodegener, 10 (1), 18
DOI 10.1186/s40035-021-00244-3, PubMed 34099032

Andersen E, Chollet ME, Sletten M, Stavik B, Skarpen E, Backe PH, Thiede B, Glosli H, Henriksson CE, Iversen N (2021)
Molecular Characterization of Two Homozygous Factor VII Variants Associated with Intracranial Bleeding
Thromb Haemost
DOI 10.1055/a-1450-8568, PubMed 33742435

Andréasson M, Lagali N, Badian RA, Utheim TP, Scarpa F, Colonna A, Allgeier S, Bartschat A, Köhler B, Mikut R, Reichert KM, Solders G, Samuelsson K, Zetterberg H, Blennow K, Svenningsson P (2021)
Parkinson's disease with restless legs syndrome-an in vivo corneal confocal microscopy study
NPJ Parkinsons Dis, 7 (1), 4
DOI 10.1038/s41531-020-00148-5, PubMed 33402694

Aprigliano R, Aksu ME, Bradamante S, Mihaljevic B, Wang W, Rian K, Montaldo NP, Grooms KM, Fordyce Martin SL, Bordin DL, Bosshard M, Peng Y, Alexov E, Skinner C, Liabakk NB, Sullivan GJ, Bjørås M, Schwartz CE, van Loon B (2021)
Increased p53 signaling impairs neural differentiation in HUWE1-promoted intellectual disabilities
Cell Rep Med, 2 (4), 100240
DOI 10.1016/j.xcrm.2021.100240, PubMed 33948573

Bjerring AW, Fosså SD, Haugnes HS, Nome R, Stokke TM, Haugaa KH, Kiserud CE, Edvardsen T, Sarvari SI (2021)
The cardiac impact of cisplatin-based chemotherapy in survivors of testicular cancer: a 30-year follow-up
Eur Heart J Cardiovasc Imaging, 22 (4), 443-450
DOI 10.1093/ehjci/jeaa289, PubMed 33152065

Bjørnetrø T, Steffensen LA, Vestad B, Brusletto BS, Olstad OK, Trøseid AM, Aass HCD, Haug KBF, Llorente A, Bøe SO, Lång A, Samiappan R, Redalen KR, Øvstebø R, Ree AH (2021)
Uptake of circulating extracellular vesicles from rectal cancer patients and differential responses by human monocyte cultures
FEBS Open Bio, 11 (3), 724-740
DOI 10.1002/2211-5463.13098, PubMed 33512765

Carr E, Bendayan R, Bean D, Stammers M, Wang W, Zhang H, Searle T, Kraljevic Z, Shek A, Phan HTT, Muruet W, Gupta RK, Shinton AJ, Wyatt M, Shi T, Zhang X, Pickles A, Stahl D, Zakeri R, Noursadeghi M, O'Gallagher K, Rogers M, Folarin A, Karwath A, Wickstrøm KE et al. (2021)
Evaluation and improvement of the National Early Warning Score (NEWS2) for COVID-19: a multi-hospital study
BMC Med, 19 (1), 23
DOI 10.1186/s12916-020-01893-3, PubMed 33472631

Cunha ES, Chen X, Sanz-Gaitero M, Mills DJ, Luecke H (2021)
Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 Å resolution
Nat Commun, 12 (1), 230
DOI 10.1038/s41467-020-20485-6, PubMed 33431861

Dahll LK, Haave EM, Dahl SR, Aas FE, Thorsby PM (2021)
Endogenous anti-streptavidin antibodies causing erroneous laboratory results more common than anticipated
Scand J Clin Lab Invest, 81 (2), 92-103
DOI 10.1080/00365513.2020.1858493, PubMed 33502256

Dantas H, Hansen TC, Warren DJ, Mathews VJ (2021)
Shared Prosthetic Control Based on Multiple Movement Intent Decoders
IEEE Trans Biomed Eng, 68 (5), 1547-1556
DOI 10.1109/TBME.2020.3045351, PubMed 33326374

Gehin JE, Klaasen RA, Norli ES, Warren DJ, Syversen SW, Goll GL, Bjøro T, Kvien TK, Mjaavatten MD, Bolstad N (2021)
Rheumatoid factor and falsely elevated results in commercial immunoassays: data from an early arthritis cohort
Rheumatol Int
DOI 10.1007/s00296-021-04865-9, PubMed 33944985

Gehin JE, Warren DJ, Syversen SW, Lie E, Sexton J, Loli L, Wierød A, Bjøro T, Kvien TK, Bolstad N, Goll GL (2021)
Serum golimumab concentration and anti-drug antibodies are associated with treatment response and drug survival in patients with inflammatory joint diseases: data from the NOR-DMARD study
Scand J Rheumatol
DOI 10.1080/03009742.2021.1875040, PubMed 33650469

Grišić AM, Dorn-Rasmussen M, Ungar B, Brynskov J, Ilvemark JFKF, Bolstad N, Warren DJ, Ainsworth MA, Huisinga W, Ben-Horin S, Kloft C, Steenholdt C (2021)
Infliximab clearance decreases in the second and third trimesters of pregnancy in inflammatory bowel disease
United European Gastroenterol J, 9 (1), 91-101
DOI 10.1177/2050640620964619, PubMed 33079627

Hernández-Breijo B, Navarro-Compán V, Plasencia-Rodríguez C, Parodis I, Gehin JE, Martínez-Feito A, Novella-Navarro M, Mezcua A, Warren DJ, Nozal P, Pascual-Salcedo D, Balsa A (2021)
BAFF predicts immunogenicity in older patients with rheumatoid arthritis treated with TNF inhibitors
Sci Rep, 11 (1), 11632
DOI 10.1038/s41598-021-91177-4, PubMed 34079038

Hikage F, Lennikov A, Mukwaya A, Lachota M, Ida Y, Utheim TP, Chen DF, Huang H, Ohguro H (2021)
NF-κB activation in retinal microglia is involved in the inflammatory and neovascularization signaling in laser-induced choroidal neovascularization in mice
Exp Cell Res, 403 (1), 112581
DOI 10.1016/j.yexcr.2021.112581, PubMed 33811906

Johannessen KA, Wear NKS, Toska K, Hansbo M, Berg JP, Fosse E (2021)
Pathologic Blood Samples Tolerate Exposure to Vibration and High Turbulence in Simulated Drone Flights, but Plasma Samples Should be Centrifuged After Flight
IEEE J Transl Eng Health Med, 9, 4000110
DOI 10.1109/JTEHM.2021.3053172, PubMed 33542860

Khan AZ, Utheim TP, Moe MC, Aass HCD, Sapkota D, Vallenari EM, Eidet JR (2021)
The Silk Protein Sericin Promotes Viability of ARPE-19 and Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells in vitro
Curr. Eye Res., 46 (4), 504-514

Landsend ECS, Lagali N, Utheim TP (2021)
Congenital aniridia - A comprehensive review of clinical features and therapeutic approaches
Surv Ophthalmol (in press)
DOI 10.1016/j.survophthal.2021.02.011, PubMed 33675823

Lyngstadaas AV, Olsen MV, Bair JA, Hodges RR, Utheim TP, Serhan CN, Dartt DA (2021)
Pro-Resolving Mediator Annexin A1 Regulates Intracellular Ca2+ and Mucin Secretion in Cultured Goblet Cells Suggesting a New Use in Inflammatory Conjunctival Diseases
Front Immunol, 12, 618653
DOI 10.3389/fimmu.2021.618653, PubMed 33968020

Magno M, Moschowits E, Arita R, Vehof J, Utheim TP (2021)
Intraductal meibomian gland probing and its efficacy in the treatment of meibomian gland dysfunction
Surv Ophthalmol, 66 (4), 612-622
DOI 10.1016/j.survophthal.2020.11.005, PubMed 33352147

Magno MS, Daniel T, Morthen MK, Snieder H, Jansonius N, Utheim TP, Hammond CJ, Vehof J (2021)
The relationship between alcohol consumption and dry eye
Ocul Surf, 21, 87-95 (in press)
DOI 10.1016/j.jtos.2021.05.005, PubMed 34029755

Maurizi A, Ponzetti M, Gautvik KM, Reppe S, Teti A, Rucci N (2021)
Lipocalin 2 serum levels correlate with age and bone turnover biomarkers in healthy subjects but not in postmenopausal osteoporotic women
Bone Rep, 14, 101059
DOI 10.1016/j.bonr.2021.101059, PubMed 34026950

Mellembakken JR, Mahmoudan A, Mørkrid L, Sundström-Poromaa I, Morin-Papunen L, Tapanainen JS, Piltonen TT, Hirschberg AL, Stener-Victorin E, Vanky E, Ravn P, Jensen RC, Andersen MS, Glintborg D (2021)
Higher blood pressure in normal weight women with PCOS compared to controls
Endocr Connect, 10 (2), 154-163
DOI 10.1530/EC-20-0527, PubMed 33416512

Morthen MK, Magno MS, Utheim TP, Snieder H, Hammond CJ, Vehof J (2021)
The physical and mental burden of dry eye disease: A large population-based study investigating the relationship with health-related quality of life and its determinants
Ocul Surf, 21, 107-117 (in press)
DOI 10.1016/j.jtos.2021.05.006, PubMed 34044135

Olsen E, Holzhauer B, Julius S, Kjeldsen SE, Larstorp ACK, Mancia G, Mehlum MH, Mo R, Rostrup M, Søraas CL, Zappe D, Weber MA (2021)
Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus and hypertension
Blood Press, 30 (2), 82-89
DOI 10.1080/08037051.2020.1855968, PubMed 33403886

Olsen E, Holzhauer B, Julius S, Kjeldsen SE, Larstorp ACK, Mancia G, Mehlum MH, Mo R, Rostrup M, Søraas CL, Zappe D, Weber MA (2021)
Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus compared to all middle-aged and elderly hypertensive study patients with high cardiovascular risk
Blood Press, 30 (2), 90-97
DOI 10.1080/08037051.2020.1856642, PubMed 33403890

Rowe AD, Stoway SD, Åhlman H, Arora V, Caggana M, Fornari A, Hagar A, Hall PL, Marquardt GC, Miller BJ, Nixon C, Norgan AP, Orsini JJ, Pettersen RD, Piazza AL, Schubauer NR, Smith AC, Tang H, Tavakoli NP, Wei S, Zetterström RH, Currier RJ, Mørkrid L, Rinaldo P (2021)
A Novel Approach to Improve Newborn Screening for Congenital Hypothyroidism by Integrating Covariate-Adjusted Results of Different Tests into CLIR Customized Interpretive Tools
Int J Neonatal Screen, 7 (2)
DOI 10.3390/ijns7020023, PubMed 33922835

Skauby RH, Gustavsen MT, Andersen AM, Bjerre A, Åsberg A, Midtvedt K, Vethe NT, Bergan S (2021)
Prednisolone and Prednisone Pharmacokinetics in Adult Renal Transplant Recipients
Ther Drug Monit, 43 (2), 247-255
DOI 10.1097/FTD.0000000000000835, PubMed 33181621

Syversen SW, Goll GL, Jørgensen KK, Sandanger Ø, Sexton J, Olsen IC, Gehin JE, Warren DJ, Brun MK, Klaasen RA, Karlsen LN, Noraberg G, Zettel C, Ljoså MKA, Haugen AJ, Njålla RJ, Bruun TJ, Seeberg KA, Michelsen B, Strand EK, Skorpe S, Blomgren IM, Bragnes YH, Dotterud CK, Thune T et al. (2021)
Effect of Therapeutic Drug Monitoring vs Standard Therapy During Infliximab Induction on Disease Remission in Patients With Chronic Immune-Mediated Inflammatory Diseases: A Randomized Clinical Trial
JAMA, 325 (17), 1744-1754
DOI 10.1001/jama.2021.4172, PubMed 33944876

Thomseth VM, Ushakova A, Krohn J, Utheim TP, Austeng D, Fossen K, Varhaug P, Malmin A, Skeiseid L, Tharaldsen A, Lindtjørn B, Johannesen H, Juul J, Forsaa VA (2021)
STRUCTURAL PATHOLOGY AFTER RETINAL DETACHMENT: MULTICOLOR CONFOCAL SCANNING LASER OPHTHALMOSCOPY VERSUS COLOR FUNDUS PHOTOGRAPHY
Retina (in press)
DOI 10.1097/IAE.0000000000003113, PubMed 33464027

Thorsby PM, Gjelstad A (2021)
When the patient is an athlete
Tidsskr Nor Laegeforen, 141 (7)
DOI 10.4045/tidsskr.21.0074, PubMed 33950644

Undrum Bergland O, Larstorp ACK, Lund Søraas C, Høieggen A, Rostrup M, Norheim Kjaer V, Godang K, Sevre K, Fadl Elmula FEM (2021)
Changes in sympathetic nervous system activity after renal denervation: results from the randomised Oslo RDN study
Blood Press, 30 (3), 154-164
DOI 10.1080/08037051.2020.1868286, PubMed 33399016

Wendel K, Pfeiffer HCV, Fugelseth DM, Nestaas E, Domellöf M, Skålhegg BS, Elgstøen KBP, Rootwelt H, Pettersen RD, Pripp AH, Stiris T, Moltu SJ, ImNuT Collaboration Group (2021)
Effects of nutrition therapy on growth, inflammation and metabolism in immature infants: a study protocol of a double-blind randomized controlled trial (ImNuT)
BMC Pediatr, 21 (1), 19
DOI 10.1186/s12887-020-02425-x, PubMed 33407269

Westgaard KL, Hynne H, Amdal CD, Young A, Singh PB, Chen X, Rykke M, Hove LH, Aqrawi LA, Utheim TP, Herlofson BB, Jensen JL (2021)
Oral and ocular late effects in head and neck cancer patients treated with radiotherapy
Sci Rep, 11 (1), 4026
DOI 10.1038/s41598-021-83635-w, PubMed 33597629

Yazdani M, Fiskådal J, Chen X, Utheim ØA, Ræder S, Vitelli V, Utheim TP (2021)
Tear Film Break-Up Time and Dry Eye Disease Severity in a Large Norwegian Cohort
J Clin Med, 10 (4)
DOI 10.3390/jcm10040884, PubMed 33671667

Yuzefovych LV, Kahn AG, Schuler MA, Eide L, Arora R, Wilson GL, Tan M, Rachek LI (2021)
Correction: Mitochondrial DNA Repair through OGG1 Activity Attenuates Breast Cancer Progression and Metastasis
Cancer Res, 81 (11), 3144
DOI 10.1158/0008-5472.CAN-21-1000, PubMed 34087783

Zawadzka M, Ràcz B, Ambrosini D, Görbitz CH, Morth JP, Wilkins AL, Østeby A, Elgstøen KBP, Lundanes E, Rise F, Ringvold A, Wilson SR (2021)
Searching for a UV-filter in the eyes of high-flying birds
Sci Rep, 11 (1), 273
DOI 10.1038/s41598-020-79533-2, PubMed 33431985

 
Page visits: 595691