Biomedical research at Oslo University Hospital

Publications (original articles or review articles) published in 2019 from OUS - Department of Immunology (Div LabMed)

101 publications found

Al-Modawi RN, Brinchmann JE, Karlsen TA (2019)
Multi-pathway Protective Effects of MicroRNAs on Human Chondrocytes in an In Vitro Model of Osteoarthritis
Mol Ther Nucleic Acids, 17, 776-790
DOI 10.1016/j.omtn.2019.07.011, PubMed 31446120

Alexandrova E, Giurato G, Saggese P, Pecoraro G, Lamberti J, Ravo M, Rizzo F, Rocco D, Tarallo R, Nyman TA, Collina F, Cantile M, Di Bonito M, Botti G, Nassa G, Weisz A (2019)
Interaction Proteomics Identifies ERbeta Association with Chromatin Repressive Complexes to Inhibit Cholesterol Biosynthesis and Exert An Oncosuppressive Role in Triple-negative Breast Cancer
Mol Cell Proteomics, 19 (2), 245-260
DOI 10.1074/mcp.RA119.001817, PubMed 31792072

Andersen TK, Huszthy PC, Gopalakrishnan RP, Jacobsen JT, Fauskanger M, Tveita AA, Grødeland G, Bogen B (2019)
Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules
NPJ Vaccines, 4, 9
DOI 10.1038/s41541-019-0101-0, PubMed 30775000

Barta Z, Czompa L, Rentka A, Zold E, Remenyik J, Biro A, Gesztelyi R, Zsuga J, Szodoray P, Kemeny-Beke A (2019)
Evaluation of Objective Signs and Subjective Symptoms of Dry Eye Disease in Patients with Inflammatory Bowel Disease
Biomed Res Int, 2019, 8310583
DOI 10.1155/2019/8310583, PubMed 30729131

Bartolomé-Casado R, Landsverk OJB, Chauhan SK, Richter L, Phung D, Greiff V, Risnes LF, Yao Y, Neumann RS, Yaqub S, Øyen O, Horneland R, Aandahl EM, Paulsen V, Sollid LM, Qiao SW, Baekkevold ES, Jahnsen FL (2019)
Resident memory CD8 T cells persist for years in human small intestine
J Exp Med, 216 (10), 2412-2426
DOI 10.1084/jem.20190414, PubMed 31337737

Bauer PR, Chevret S, Yadav H, Mehta S, Pickkers P, Bukan RB, Rello J, van de Louw A, Klouche K, Meert AP, Martin-Loeches I, Marsh B, Socias Crespi L, Moreno-Gonzalez G, Buchtele N, Amrein K, Balik M, Antonelli M, Nyunga M, Barratt-Due A, Bergmans DCJJ, Spoelstra-de Man AME, Kuitunen A, Wallet F, Seguin A et al. (2019)
Diagnosis and outcome of acute respiratory failure in immunocompromised patients after bronchoscopy
Eur Respir J, 54 (1)
DOI 10.1183/13993003.02442-2018, PubMed 31109985

Blumberg LJ, Humphries JE, Jones SD, Pearce LB, Holgate R, Hearn A, Cheung J, Mahmood A, Del Tito B, Graydon JS, Stolz LE, Bitonti A, Purohit S, de Graaf D, Kacena K, Andersen JT, Christianson GJ, Roopenian DC, Hubbard JJ, Gandhi AK, Lasseter K, Pyzik M, Blumberg RS (2019)
Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses
Sci Adv, 5 (12), eaax9586
DOI 10.1126/sciadv.aax9586, PubMed 31897428

Bogdanova M, Zabirnyk A, Malashicheva A, Enayati KZ, Karlsen TA, Kaljusto ML, Kvitting JP, Dissen E, Sullivan GJ, Kostareva A, Stensløkken KO, Rutkovskiy A, Vaage J (2019)
Interstitial cells in calcified aortic valves have reduced differentiation potential and stem cell-like properties
Sci Rep, 9 (1), 12934
DOI 10.1038/s41598-019-49016-0, PubMed 31506459

Bogen B, Fauskanger M, Haabeth OA, Tveita A (2019)
CD4⁺ T cells indirectly kill tumor cells via induction of cytotoxic macrophages in mouse models
Cancer Immunol Immunother, 68 (11), 1865-1873
DOI 10.1007/s00262-019-02374-0, PubMed 31448380

Bottermann M, Foss S, Caddy SL, Clift D, van Tienen LM, Vaysburd M, Cruickshank J, O'Connell K, Clark J, Mayes K, Higginson K, Lode HE, McAdam MB, Sandlie I, Andersen JT, James LC (2019)
Complement C4 Prevents Viral Infection through Capsid Inactivation
Cell Host Microbe, 25 (4), 617-629.e7
DOI 10.1016/j.chom.2019.02.016, PubMed 30926239

Brekke OL, Christiansen D, Kisserli A, Fure H, Dahl JA, Donvito B, Reveil B, Ludviksen JK, Tabary T, Mollnes TE, Cohen JHM (2019)
Key role of the number of complement receptor 1 on erythrocytes for binding of Escherichia coli to erythrocytes and for leukocyte phagocytosis and oxidative burst in human whole blood
Mol Immunol, 114, 139-148
DOI 10.1016/j.molimm.2019.07.014, PubMed 31352230

Brennecke P, Rasina D, Aubi O, Herzog K, Landskron J, Cautain B, Vicente F, Quintana J, Mestres J, Stechmann B, Ellinger B, Brea J, Kolanowski JL, Pilarski R, Orzaez M, Pineda-Lucena A, Laraia L, Nami F, Zielenkiewicz P, Paruch K, Hansen E, von Kries JP, Neuenschwander M, Specker E, Bartunek P et al. (2019)
EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
SLAS Discov, 24 (3), 398-413
DOI 10.1177/2472555218816276, PubMed 30616481

Brunet A, Forsberg F, Fan Q, Sæther T, Collas P (2019)
Nuclear Lamin B1 Interactions With Chromatin During the Circadian Cycle Are Uncoupled From Periodic Gene Expression
Front Genet, 10, 917
DOI 10.3389/fgene.2019.00917, PubMed 31632442

Bruun T, Nakstad B, Greve-Isdahl M, Hovde H, Leegaard TM, Flem E (2019)
Premature infants should receive early vaccination against rotavirus
Tidsskr Nor Laegeforen, 139 (10)
DOI 10.4045/tidsskr.19.0079, PubMed 31238656

Bugge E, Wynn R, Mollnes TE, Reitan SK, Lapid MI, Grønli OK (2019)
Changes in cytokines during treatment of elderly, hospitalized psychiatric patients - a naturalistic study
Psychoneuroendocrinology, 108, 135-139
DOI 10.1016/j.psyneuen.2019.06.014, PubMed 31276906

Cassetta L, Baekkevold ES, Brandau S, Bujko A, Cassatella MA, Dorhoi A, Krieg C, Lin A, Loré K, Marini O, Pollard JW, Roussel M, Scapini P, Umansky V, Adema GJ (2019)
Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates
Cancer Immunol Immunother, 68 (4), 687-697
DOI 10.1007/s00262-019-02302-2, PubMed 30684003

Chellappa S, Kushekhar K, Munthe LA, Tjønnfjord GE, Aandahl EM, Okkenhaug K, Taskén K (2019)
The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function
J Immunol, 202 (5), 1397-1405
DOI 10.4049/jimmunol.1701703, PubMed 30692213

Christophersen A, Lund EG, Snir O, Solà E, Kanduri C, Dahal-Koirala S, Zühlke S, Molberg Ø, Utz PJ, Rohani-Pichavant M, Simard JF, Dekker CL, Lundin KEA, Sollid LM, Davis MM (2019)
Distinct phenotype of CD4⁺ T cells driving celiac disease identified in multiple autoimmune conditions
Nat Med, 25 (5), 734-737
DOI 10.1038/s41591-019-0403-9, PubMed 30911136

Christophersen A, Risnes LF, Dahal-Koirala S, Sollid LM (2019)
Therapeutic and Diagnostic Implications of T Cell Scarring in Celiac Disease and Beyond
Trends Mol Med, 25 (10), 836-852
DOI 10.1016/j.molmed.2019.05.009, PubMed 31331739

Clausen FB, Barrett AN, Noninvasive Fetal RHD Genotyping EQA2017 Working Group (2019)
Noninvasive fetal RHD genotyping to guide targeted anti-D prophylaxis-an external quality assessment workshop
Vox Sang, 114 (4), 386-393
DOI 10.1111/vox.12768, PubMed 30834546

Collas P, Liyakat Ali TM, Brunet A, Germier T (2019)
Finding Friends in the Crowd: Three-Dimensional Cliques of Topological Genomic Domains
Front Genet, 10, 602
DOI 10.3389/fgene.2019.00602, PubMed 31275364

Czompa L, Barta Z, Ziad H, Nemeth G, Rentka A, Aszalos Z, Zold E, Gesztelyi R, Zsuga J, Szodoray P, Kemeny-Beke A (2019)
Corneal Manifestations of Inflammatory Bowel Disease
Semin Ophthalmol, 34 (7-8), 543-550
DOI 10.1080/08820538.2019.1684525, PubMed 31657260

Dahal-Koirala S, Neumann RS, Jahnsen J, Lundin KEA, Sollid LM (2019)
On the immune response to barley in celiac disease: Biased and public T-cell receptor usage to a barley unique and immunodominant gluten epitope
Eur J Immunol, 50 (2), 256-269
DOI 10.1002/eji.201948253, PubMed 31628754

Dahm AEA, Jacobsen EM, Wik HS, Jacobsen AF, Mollnes TE, Kanse SM, Sandset PM (2019)
Elevated Complement C3 and C4 Levels are Associated with Postnatal Pregnancy-Related Venous Thrombosis
Thromb Haemost, 119 (9), 1481-1488
DOI 10.1055/s-0039-1692426, PubMed 31254974

Eggesbø LM, Risnes LF, Neumann RS, Lundin KEA, Christophersen A, Sollid LM (2019)
Single-cell TCR sequencing of gut intraepithelial γδ T cells reveals a vast and diverse repertoire in celiac disease
Mucosal Immunol, 13 (2), 313-321
DOI 10.1038/s41385-019-0222-9, PubMed 31728027

Exner ND, Valenzuela JAC, Abou-El-Ardat K, Miletic H, Huszthy PC, Radehaus PM, Schröck E, Bjerkvig R, Kaderali L, Klink B, Nigro JM (2019)
Deep sequencing of a recurrent oligodendroglioma and the derived xenografts reveals new insights into the evolution of human oligodendroglioma and candidate driver genes
Oncotarget, 10 (38), 3641-3653
DOI 10.18632/oncotarget.26950, PubMed 31217899

Forsberg F, Brunet A, Ali TML, Collas P (2019)
Interplay of lamin A and lamin B LADs on the radial positioning of chromatin
Nucleus, 10 (1), 7-20
DOI 10.1080/19491034.2019.1570810, PubMed 30663495

Foss S, Bottermann M, Jonsson A, Sandlie I, James LC, Andersen JT (2019)
TRIM21-From Intracellular Immunity to Therapy
Front Immunol, 10, 2049
DOI 10.3389/fimmu.2019.02049, PubMed 31555278

Gidoni M, Snir O, Peres A, Polak P, Lindeman I, Mikocziova I, Sarna VK, Lundin KEA, Clouser C, Vigneault F, Collins AM, Sollid LM, Yaari G (2019)
Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping
Nat Commun, 10 (1), 628
DOI 10.1038/s41467-019-08489-3, PubMed 30733445

Goel G, Tye-Din JA, Qiao SW, Russell AK, Mayassi T, Ciszewski C, Sarna VK, Wang S, Goldstein KE, Dzuris JL, Williams LJ, Xavier RJ, Lundin KEA, Jabri B, Sollid LM, Anderson RP (2019)
Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease
Sci Adv, 5 (8), eaaw7756
DOI 10.1126/sciadv.aaw7756, PubMed 31457091

Granslo HN, Aarag Fredheim EG, Esaiassen E, Christophersen L, Jensen PØ, Mollnes TE, Moser C, Flaegstad T, Klingenberg C, Cavanagh JP (2019)
The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model
APMIS, 127 (6), 475-483
DOI 10.1111/apm.12946, PubMed 30916807

Gravastrand CS, Steinkjer B, Halvorsen B, Landsem A, Skjelland M, Jacobsen EA, Woodruff TM, Lambris JD, Mollnes TE, Brekke OL, Espevik T, Rokstad AMA (2019)
Cholesterol Crystals Induce Coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor
J Immunol, 203 (4), 853-863
DOI 10.4049/jimmunol.1900503, PubMed 31270150

Grodeland G, Fossum E, Bogen B (2019)
Targeting of HA to chemokine receptors induces strong and cross-reactive T cell responses after DNA vaccination in pigs
Vaccine, 38 (6), 1280-1285
DOI 10.1016/j.vaccine.2019.11.084, PubMed 31836256

Gudjonsson A, Andersen TK, Sundvold-Gjerstad V, Bogen B, Fossum E (2019)
Endocytosis Deficient Murine Xcl1-Fusion Vaccine Enhances Protective Antibody Responses in Mice
Front Immunol, 10, 1086
DOI 10.3389/fimmu.2019.01086, PubMed 31156636

Haabeth OAW, Blake TR, McKinlay CJ, Tveita AA, Sallets A, Waymouth RM, Wender PA, Levy R (2019)
Local Delivery of Ox40l, Cd80, and Cd86 mRNA Kindles Global Anticancer Immunity
Cancer Res, 79 (7), 1624-1634
DOI 10.1158/0008-5472.CAN-18-2867, PubMed 30692215

Hagve M, Gjessing PF, Hole MJ, Jansen KM, Fuskevåg OM, Mollnes TE, Larsen TS, Irtun Ø (2019)
Perioperative Infusion of Glucagon-Like Peptide-1 Prevents Insulin Resistance After Surgical Trauma in Female Pigs
Endocrinology, 160 (12), 2892-2902
DOI 10.1210/en.2019-00374, PubMed 31589305

Hardersen R, Enebakk T, Christiansen D, Ludviksen JK, Mollnes TE, Lappegård KT, Hovland A (2019)
Comparison of cytokine changes in three different lipoprotein apheresis systems in an ex vivo whole blood model
J Clin Apher, 35 (2), 104-116
DOI 10.1002/jca.21765, PubMed 31782556

Hiltunen AK, Savijoki K, Nyman TA, Miettinen I, Ihalainen P, Peltonen J, Fallarero A (2019)
Structural and Functional Dynamics of Staphylococcus aureus Biofilms and Biofilm Matrix Proteins on Different Clinical Materials
Microorganisms, 7 (12)
DOI 10.3390/microorganisms7120584, PubMed 31756969

Høiland II, Liang RA, Braekkan SK, Pettersen K, Ludviksen JK, Latysheva N, Snir O, Ueland T, Hindberg K, Mollnes TE, Hansen JB (2019)
Complement activation assessed by the plasma terminal complement complex and future risk of venous thromboembolism
J Thromb Haemost, 17 (6), 934-943
DOI 10.1111/jth.14438, PubMed 30920726

Hokstad I, Deyab G, Wang Fagerland M, Lyberg T, Hjeltnes G, Førre Ø, Agewall S, Mollnes TE, Hollan I (2019)
Tumor necrosis factor inhibitors are associated with reduced complement activation in spondylarthropathies: An observational study
PLoS One, 14 (7), e0220079
DOI 10.1371/journal.pone.0220079, PubMed 31335881

Holt M, Seim BE, Øgaard J, Olsen MB, Woldbæk PR, Kvitting JP, Aukrust P, Yndestad A, Mollnes TE, Nilsson PH, Louwe MC, Ranheim T (2019)
Selective and marked decrease of complement receptor C5aR2 in human thoracic aortic aneurysms: a dysregulation with potential inflammatory effects
Open Heart, 6 (2), e001098
DOI 10.1136/openhrt-2019-001098, PubMed 31798913

Høydahl LS, Frick R, Sandlie I, Løset GÅ (2019)
Targeting the MHC Ligandome by Use of TCR-Like Antibodies
Antibodies (Basel), 8 (2)
DOI 10.3390/antib8020032, PubMed 31544838

Hung SC, Hou T, Jiang W, Wang N, Qiao SW, Chow IT, Liu X, van der Burg SH, Koelle DM, Kwok WW, Sollid LM, Mellins ED (2019)
Epitope Selection for HLA-DQ2 Presentation: Implications for Celiac Disease and Viral Defense
J Immunol, 202 (9), 2558-2569
DOI 10.4049/jimmunol.1801454, PubMed 30926644

Huszthy PC, Gopalakrishnan RP, Jacobsen JT, Haabeth OAW, Løset GÅ, Braathen R, Schenck K, Tveita AA, Munthe LA, Bogen B (2019)
B cell receptor ligation induces display of V-region peptides on MHC class II molecules to T cells
Proc Natl Acad Sci U S A, 116 (51), 25850-25859
DOI 10.1073/pnas.1902836116, PubMed 31796587

Idaszek J, Costantini M, Karlsen TA, Jaroszewicz J, Colosi C, Testa S, Fornetti E, Bernardini S, Seta M, Kasarełło K, Wrzesień R, Cannata S, Barbetta A, Gargioli C, Brinchman JE, Święszkowski W (2019)
3D bioprinting of hydrogel constructs with cell and material gradients for the regeneration of full-thickness chondral defect using a microfluidic printing head
Biofabrication, 11 (4), 044101
DOI 10.1088/1758-5090/ab2622, PubMed 31151123

Islam MM, Sharifi R, Mamodaly S, Islam R, Nahra D, Abusamra DB, Hui PC, Adibnia Y, Goulamaly M, Paschalis EI, Cruzat A, Kong J, Nilsson PH, Argüeso P, Mollnes TE, Chodosh J, Dohlman CH, Gonzalez-Andrades M (2019)
Effects of gamma radiation sterilization on the structural and biological properties of decellularized corneal xenografts
Acta Biomater, 96, 330-344
DOI 10.1016/j.actbio.2019.07.002, PubMed 31284096

Iversen R, Roy B, Stamnaes J, Høydahl LS, Hnida K, Neumann RS, Korponay-Szabó IR, Lundin KEA, Sollid LM (2019)
Efficient T cell-B cell collaboration guides autoantibody epitope bias and onset of celiac disease
Proc Natl Acad Sci U S A, 116 (30), 15134-15139
DOI 10.1073/pnas.1901561116, PubMed 31285344

Johnson E, Therkelsen SP, Nentwich I, Nissen-Meyer LSH, Hetland G (2019)
IgE-sensitization to food and inhalant allergens in IBD patients compared with normal blood donors at Oslo University Hospital, Norway
Scand J Gastroenterol, 54 (9), 1107-1110
DOI 10.1080/00365521.2019.1663445, PubMed 31524013

Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B (2019)
Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 9 (1), 167
DOI 10.1038/s41598-018-35367-7, PubMed 30655568

Karlsen TA, Aae TF, Brinchmann JE (2019)
Robust profiling of microRNAs and isomiRs in human plasma exosomes across 46 individuals
Sci Rep, 9 (1), 19999
DOI 10.1038/s41598-019-56593-7, PubMed 31882820

Karlsen TA, Sundaram AYM, Brinchmann JE (2019)
Single-Cell RNA Sequencing of In Vitro Expanded Chondrocytes: MSC-Like Cells With No Evidence of Distinct Subsets
Cartilage, 1947603519847746 (in press)
DOI 10.1177/1947603519847746, PubMed 31072202

Kemeny-Beke A, Szodoray P (2019)
Ocular manifestations of rheumatic diseases
Int Ophthalmol, 40 (2), 503-510
DOI 10.1007/s10792-019-01183-9, PubMed 31583550

Kjeldsen-Kragh J, Titze TL, Lie BA, Vaage JT, Kjær M (2019)
HLA-DRB3*01:01 exhibits a dose-dependent impact on HPA-1a antibody levels in HPA-1a-immunized women
Blood Adv, 3 (7), 945-951
DOI 10.1182/bloodadvances.2019032227, PubMed 30923048

Kosik-Kozioł A, Costantini M, Mróz A, Idaszek J, Heljak M, Jaroszewicz J, Kijeńska E, Szöke K, Frerker N, Barbetta A, Brinchmann JE, Święszkowski W (2019)
3D bioprinted hydrogel model incorporating β-tricalcium phosphate for calcified cartilage tissue engineering
Biofabrication, 11 (3), 035016
DOI 10.1088/1758-5090/ab15cb, PubMed 30943457

Kozma GT, Mészáros T, Vashegyi I, Fülöp T, Örfi E, Dézsi L, Rosivall L, Bavli Y, Urbanics R, Mollnes TE, Barenholz Y, Szebeni J (2019)
Pseudo-anaphylaxis to Polyethylene Glycol (PEG)-Coated Liposomes: Roles of Anti-PEG IgM and Complement Activation in a Porcine Model of Human Infusion Reactions
ACS Nano, 13 (8), 9315-9324
DOI 10.1021/acsnano.9b03942, PubMed 31348638

Labzin LI, Bottermann M, Rodriguez-Silvestre P, Foss S, Andersen JT, Vaysburd M, Clift D, James LC (2019)
Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection
EMBO J, 38 (21), e101365
DOI 10.15252/embj.2018101365, PubMed 31468569

Liang RA, Høiland II, Ueland T, Aukrust P, Snir O, Hindberg K, Braekkan SK, Garred P, Mollnes TE, Hansen JB (2019)
Plasma levels of mannose-binding lectin and future risk of venous thromboembolism
J Thromb Haemost, 17 (10), 1661-1669
DOI 10.1111/jth.14539, PubMed 31220397

Lin A, Sved Skottvoll F, Rayner S, Pedersen-Bjergaard S, Sullivan G, Krauss S, Ray Wilson S, Harrison S (2019)
3D cell culture models and organ-on-a-chip: Meet separation science and mass spectrometry
Electrophoresis, 41 (1-2), 56-64
DOI 10.1002/elps.201900170, PubMed 31544246

Lode HE, Gjølberg TT, Foss S, Sivertsen MS, Brustugun J, Andersson Y, Jørstad ØK, Moe MC, Andersen JT (2019)
A new method for pharmaceutical compounding and storage of anti-VEGF biologics for intravitreal use in silicone oil-free prefilled plastic syringes
Sci Rep, 9 (1), 18021
DOI 10.1038/s41598-019-54226-7, PubMed 31792234

Lunde A, Okaty BW, Dymecki SM, Glover JC (2019)
Molecular Profiling Defines Evolutionarily Conserved Transcription Factor Signatures of Major Vestibulospinal Neuron Groups
eNeuro, 6 (1)
DOI 10.1523/ENEURO.0475-18.2019, PubMed 30899776

Lunde NN, Gregersen I, Ueland T, Shetelig C, Holm S, Kong XY, Michelsen AE, Otterdal K, Yndestad A, Broch K, Gullestad L, Nyman TA, Bendz B, Eritsland J, Hoffmann P, Skagen K, Gonçalves I, Nilsson J, Grenegård M, Poreba M, Drag M, Seljeflot I, Sporsheim B, Espevik T, Skjelland M et al. (2019)
Legumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages
Atherosclerosis, 296, 74-82
DOI 10.1016/j.atherosclerosis.2019.12.008, PubMed 31870625

Lysén A, Braathen R, Gudjonsson A, Tesfaye DY, Bogen B, Fossum E (2019)
Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site
Sci Rep, 9 (1), 1820
DOI 10.1038/s41598-018-38080-7, PubMed 30755656

Maaland AF, Heyerdahl H, O'Shea A, Eiriksdottir B, Pascal V, Andersen JT, Kolstad A, Dahle J (2019)
Targeting B-cell malignancies with the beta-emitting anti-CD37 radioimmunoconjugate ¹⁷⁷Lu-NNV003
Eur J Nucl Med Mol Imaging, 46 (11), 2311-2321
DOI 10.1007/s00259-019-04417-1, PubMed 31309259

Macpherson ME, Halvorsen B, Yndestad A, Ueland T, Mollnes TE, Berge RK, Rashidi A, Otterdal K, Gregersen I, Kong XY, Holven KB, Aukrust P, Fevang B, Jørgensen SF (2019)
Impaired HDL Function Amplifies Systemic Inflammation in Common Variable Immunodeficiency
Sci Rep, 9 (1), 9427
DOI 10.1038/s41598-019-45861-1, PubMed 31263122

Mahalunkar S, Yadav AS, Gorain M, Pawar V, Braathen R, Weiss S, Bogen B, Gosavi SW, Kundu GC (2019)
Functional design of pH-responsive folate-targeted polymer-coated gold nanoparticles for drug delivery and in vivo therapy in breast cancer
Int J Nanomedicine, 14, 8285-8302
DOI 10.2147/IJN.S215142, PubMed 31802866

Mahmood F, Hetland G, Nentwich I, Mirlashari MR, Ghiasvand R, Nissen-Meyer LSH (2019)
Agaricus blazei-Based Mushroom Extract Supplementation to Birch Allergic Blood Donors: A Randomized Clinical Trial
Nutrients, 11 (10)
DOI 10.3390/nu11102339, PubMed 31581605

Mastellos DC, Blom AM, Connolly ES, Daha MR, Geisbrecht BV, Ghebrehiwet B, Gros P, Hajishengallis G, Holers VM, Huber-Lang M, Kinoshita T, Mollnes TE, Montgomery RA, Morgan BP, Nilsson B, Pio R, Ricklin D, Risitano AM, Taylor RP, Mantovani A, Ioannidis JPA, Lambris JD (2019)
'Stealth' corporate innovation: an emerging threat for therapeutic drug development
Nat Immunol, 20 (11), 1409-1413
DOI 10.1038/s41590-019-0503-1, PubMed 31562490

Mathiesen SB, Lunde M, Aronsen JM, Romaine A, Kaupang A, Martinsen M, de Souza GA, Nyman TA, Sjaastad I, Christensen G, Carlson CR (2019)
The cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP)
J Biol Chem, 294 (22), 8717-8731
DOI 10.1074/jbc.RA118.006423, PubMed 30967474

Miragaia RJ, Gomes T, Chomka A, Jardine L, Riedel A, Hegazy AN, Whibley N, Tucci A, Chen X, Lindeman I, Emerton G, Krausgruber T, Shields J, Haniffa M, Powrie F, Teichmann SA (2019)
Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation
Immunity, 50 (2), 493-504.e7
DOI 10.1016/j.immuni.2019.01.001, PubMed 30737144

Mooij P, Grødeland G, Koopman G, Andersen TK, Mortier D, Nieuwenhuis IG, Verschoor EJ, Fagrouch Z, Bogers WM, Bogen B (2019)
Needle-free delivery of DNA: Targeting of hemagglutinin to MHC class II molecules protects rhesus macaques against H1N1 influenza
Vaccine, 37 (6), 817-826
DOI 10.1016/j.vaccine.2018.12.049, PubMed 30638800

Myhr KM, Torkildsen Ø, Lossius A, Bø L, Holmøy T (2019)
B cell depletion in the treatment of multiple sclerosis
Expert Opin Biol Ther, 19 (3), 261-271
DOI 10.1080/14712598.2019.1568407, PubMed 30632834

Nassa G, Giurato G, Salvati A, Gigantino V, Pecoraro G, Lamberti J, Rizzo F, Nyman TA, Tarallo R, Weisz A (2019)
The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei
Sci Data, 6 (1), 173
DOI 10.1038/s41597-019-0179-2, PubMed 31527615

Nassa G, Salvati A, Tarallo R, Gigantino V, Alexandrova E, Memoli D, Sellitto A, Rizzo F, Malanga D, Mirante T, Morelli E, Nees M, Åkerfelt M, Kangaspeska S, Nyman TA, Milanesi L, Giurato G, Weisz A (2019)
Inhibition of histone methyltransferase DOT1L silences ERα gene and blocks proliferation of antiestrogen-resistant breast cancer cells
Sci Adv, 5 (2), eaav5590
DOI 10.1126/sciadv.aav5590, PubMed 30775443

Ottestad W, Rognes IN, Pischke SE, Mollnes TE, Andersson U, Eken T (2019)
Biphasic Release of the Alarmin High Mobility Group Box 1 Protein Early After Trauma Predicts Poor Clinical Outcome
Crit Care Med, 47 (8), e614-e622
DOI 10.1097/CCM.0000000000003800, PubMed 31162203

Paulsen J, Liyakat Ali TM, Nekrasov M, Delbarre E, Baudement MO, Kurscheid S, Tremethick D, Collas P (2019)
Long-range interactions between topologically associating domains shape the four-dimensional genome during differentiation
Nat Genet, 51 (5), 835-843
DOI 10.1038/s41588-019-0392-0, PubMed 31011212

Pischke SE, Hestenes S, Johansen HT, Fure H, Bugge JF, Espinoza A, Skulstad H, Edvardsen T, Fosse E, Mollnes TE, Halvorsen PS, Nielsen EW (2019)
Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model
PLoS One, 14 (6), e0218624
DOI 10.1371/journal.pone.0218624, PubMed 31247004

Post JI, Leergaard TB, Ratz V, Walaas SI, von Hörsten S, Nissen-Meyer LSH (2019)
Differential Levels and Phosphorylation of Type 1 Inositol 1,4,5-Trisphosphate Receptor in Four Different Murine Models of Huntington Disease
J Huntingtons Dis, 8 (3), 271-289
DOI 10.3233/JHD-180301, PubMed 31256144

Pyzik M, Sand KMK, Hubbard JJ, Andersen JT, Sandlie I, Blumberg RS (2019)
The Neonatal Fc Receptor (FcRn): A Misnomer?
Front Immunol, 10, 1540
DOI 10.3389/fimmu.2019.01540, PubMed 31354709

Qiao SW, Sollid LM (2019)
Two novel HLA-DQ2.5-restricted gluten T cell epitopes in the DQ2.5-glia-γ4 epitope family
Immunogenetics, 71 (10), 665-667
DOI 10.1007/s00251-019-01138-5, PubMed 31673720

Richter U, Ng KY, Suomi F, Marttinen P, Turunen T, Jackson C, Suomalainen A, Vihinen H, Jokitalo E, Nyman TA, Isokallio MA, Stewart JB, Mancini C, Brusco A, Seneca S, Lombès A, Taylor RW, Battersby BJ (2019)
Mitochondrial stress response triggered by defects in protein synthesis quality control
Life Sci Alliance, 2 (1)
DOI 10.26508/lsa.201800219, PubMed 30683687

Savijoki K, Nyman TA, Kainulainen V, Miettinen I, Siljamäki P, Fallarero A, Sandholm J, Satokari R, Varmanen P (2019)
Growth Mode and Carbon Source Impact the Surfaceome Dynamics of Lactobacillus rhamnosus GG
Front Microbiol, 10, 1272
DOI 10.3389/fmicb.2019.01272, PubMed 31231350

Shahini N, Ueland T, Auensen A, Michelsen AE, Ludviksen JK, Hussain AI, Pettersen KI, Aakhus S, Espeland T, Lunde IG, Kirschfink M, Nilsson PH, Mollnes TE, Gullestad L, Aukrust P, Yndestad A, Louwe MC (2019)
Increased Complement Factor B and Bb Levels Are Associated with Mortality in Patients with Severe Aortic Stenosis
J Immunol, 203 (7), 1973-1980
DOI 10.4049/jimmunol.1801244, PubMed 31492744

Shaw A, Hoffecker IT, Smyrlaki I, Rosa J, Grevys A, Bratlie D, Sandlie I, Michaelsen TE, Andersen JT, Högberg B (2019)
Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies
Nat Nanotechnol, 14 (2), 184-190
DOI 10.1038/s41565-018-0336-3, PubMed 30643273

Skånland SS, Cremaschi A, Bendiksen H, Hermansen JU, Thimiri Govinda Raj DB, Munthe LA, Tjønnfjord GE, Taskén K (2019)
An in vitro assay for biomarker discovery and dose prediction applied to ibrutinib plus venetoclax treatment of CLL
Leukemia, 34 (2), 478-487
DOI 10.1038/s41375-019-0569-7, PubMed 31471562

Skjeflo EW, Christiansen D, Landsem A, Stenvik J, Woodruff TM, Espevik T, Nielsen EW, Mollnes TE (2019)
Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14
Mol Immunol, 112, 131-139
DOI 10.1016/j.molimm.2019.03.014, PubMed 31102985

Snir O, Kanduri C, Lundin KEA, Sandve GK, Sollid LM (2019)
Transcriptional profiling of human intestinal plasma cells reveals effector functions beyond antibody production
United European Gastroenterol J, 7 (10), 1399-1407
DOI 10.1177/2050640619862461, PubMed 31839965

Sokolova M, Ranheim T, Louwe MC, Halvorsen B, Yndestad A, Aukrust P (2019)
NLRP3 Inflammasome: A Novel Player in Metabolically Induced Inflammation-Potential Influence on the Myocardium
J Cardiovasc Pharmacol, 74 (4), 276-284
DOI 10.1097/FJC.0000000000000704, PubMed 31584530

Solberg NT, Melheim M, Strand MF, Olsen PA, Krauss S (2019)
MEK Inhibition Induces Canonical WNT Signaling through YAP in KRAS Mutated HCT-15 Cells, and a Cancer Preventive FOXO3/FOXM1 Ratio in Combination with TNKS Inhibition
Cancers (Basel), 11 (2)
DOI 10.3390/cancers11020164, PubMed 30717152

Sollid LM, Tye-Din JA, Qiao SW, Anderson RP, Gianfrani C, Koning F (2019)
Update 2020: nomenclature and listing of celiac disease-relevant gluten epitopes recognized by CD4⁺ T cells
Immunogenetics, 72 (1-2), 85-88
DOI 10.1007/s00251-019-01141-w, PubMed 31735991

Spirkoski J, Shah A, Reiner AH, Collas P, Delbarre E (2019)
PML modulates H3.3 targeting to telomeric and centromeric repeats in mouse fibroblasts
Biochem Biophys Res Commun, 511 (4), 882-888
DOI 10.1016/j.bbrc.2019.02.087, PubMed 30850162

Suliman S, Ali HRW, Karlsen TA, Amiaud J, Mohamed-Ahmed S, Layrolle P, Costea DE, Brinchmann JE, Mustafa K (2019)
Impact of humanised isolation and culture conditions on stemness and osteogenic potential of bone marrow derived mesenchymal stromal cells
Sci Rep, 9 (1), 16031
DOI 10.1038/s41598-019-52442-9, PubMed 31690774

Szucs G, Szekanecz Z, Aszalos Z, Gesztelyi R, Zsuga J, Szodoray P, Kemeny-Beke A (2019)
A Wide Spectrum of Ocular Manifestations Signify Patients with Systemic Sclerosis
Ocul Immunol Inflamm, 29 (1), 81-89
DOI 10.1080/09273948.2019.1657467, PubMed 31577461

Tapia G, Mårild K, Dahl SR, Lund-Blix NA, Viken MK, Lie BA, Njølstad PR, Joner G, Skrivarhaug T, Cohen AS, Størdal K, Stene LC (2019)
Maternal and Newborn Vitamin D-Binding Protein, Vitamin D Levels, Vitamin D Receptor Genotype, and Childhood Type 1 Diabetes
Diabetes Care, 42 (4), 553-559
DOI 10.2337/dc18-2176, PubMed 30692241

Tapia G, Mortimer G, Ye J, Gillard BT, Chipper-Keating S, Mårild K, Viken MK, Lie BA, Joner G, Skrivarhaug T, Njølstad PR, Størdal K, Gillespie KM, Stene LC (2019)
Maternal microchimerism in cord blood and risk of childhood-onset type 1 diabetes
Pediatr Diabetes, 20 (6), 728-735
DOI 10.1111/pedi.12875, PubMed 31173445

Tesfaye DY, Gudjonsson A, Bogen B, Fossum E (2019)
Targeting Conventional Dendritic Cells to Fine-Tune Antibody Responses
Front Immunol, 10, 1529
DOI 10.3389/fimmu.2019.01529, PubMed 31333661

Thomas AM, Gerogianni A, McAdam MB, Fløisand Y, Lau C, Espevik T, Nilsson PH, Mollnes TE, Barratt-Due A (2019)
Complement Component C5 and TLR Molecule CD14 Mediate Heme-Induced Thromboinflammation in Human Blood
J Immunol, 203 (6), 1571-1578
DOI 10.4049/jimmunol.1900047, PubMed 31413105

Thorgersen EB, Barratt-Due A, Haugaa H, Harboe M, Pischke SE, Nilsson PH, Mollnes TE (2019)
The Role of Complement in Liver Injury, Regeneration, and Transplantation
Hepatology, 70 (2), 725-736
DOI 10.1002/hep.30508, PubMed 30653682

Tiller H, Ahlen MT, Akkök ÇA, Husebekk A (2019)
Fetal and neonatal alloimmune thrombocytopenia - The Norwegian management model
Transfus Apher Sci, 59 (1), 102711
DOI 10.1016/j.transci.2019.102711, PubMed 31911047

Tomescu-Baciu A, Johansen JN, Holmøy T, Greiff V, Stensland M, de Souza GA, Vartdal F, Lossius A (2019)
Persistence of intrathecal oligoclonal B cells and IgG in multiple sclerosis
J Neuroimmunol, 333, 576966
DOI 10.1016/j.jneuroim.2019.576966, PubMed 31153015

Tye-Din JA, Skodje GI, Sarna VK, Dzuris JL, Russell AK, Goel G, Wang S, Goldstein KE, Williams LJ, Sollid LM, Lundin KE, Anderson RP (2019)
Cytokine release after gluten ingestion differentiates coeliac disease from self-reported gluten sensitivity
United European Gastroenterol J, 8 (1), 108-118
DOI 10.1177/2050640619874173, PubMed 32213060

Yang K, Lauritzen KH, Olsen MB, Dahl TB, Ranheim T, Ahmed MS, Attramadal H, Aukrust P, Halvorsen B, Nyman TA, Sandanger Ø, Yndestad A (2019)
Low Cellular NAD⁺ Compromises Lipopolysaccharide-Induced Inflammatory Responses via Inhibiting TLR4 Signal Transduction in Human Monocytes
J Immunol, 203 (6), 1598-1608
DOI 10.4049/jimmunol.1801382, PubMed 31427442