Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2021 from OUS - Department of Microbiology

24 publications found

Aamodt AH, Høgestøl EA, Popperud TH, Holter JC, Dyrhol-Riise AM, Tonby K, Stiksrud B, Quist-Paulsen E, Berge T, Barratt-Due A, Aukrust P, Heggelund L, Blennow K, Zetterberg H, Harbo HF (2021)
Blood neurofilament light concentration at admittance: a potential prognostic marker in COVID-19
J Neurol
DOI 10.1007/s00415-021-10517-6, PubMed 33743046

Andersen E, Chollet ME, Sletten M, Stavik B, Skarpen E, Backe PH, Thiede B, Glosli H, Henriksson CE, Iversen N (2021)
Molecular Characterization of Two Homozygous Factor VII Variants Associated with Intracranial Bleeding
Thromb Haemost (in press)
DOI 10.1055/a-1450-8568, PubMed 33742435

Aprigliano R, Aksu ME, Bradamante S, Mihaljevic B, Wang W, Rian K, Montaldo NP, Grooms KM, Fordyce Martin SL, Bordin DL, Bosshard M, Peng Y, Alexov E, Skinner C, Liabakk NB, Sullivan GJ, Bjørås M, Schwartz CE, van Loon B (2021)
Increased p53 signaling impairs neural differentiation in HUWE1-promoted intellectual disabilities
Cell Rep Med, 2 (4), 100240
DOI 10.1016/j.xcrm.2021.100240, PubMed 33948573

Avershina E, Sharma P, Taxt AM, Singh H, Frye SA, Paul K, Kapil A, Naseer U, Kaur P, Ahmad R (2021)
AMR-Diag: Neural network based genotype-to-phenotype prediction of resistance towards β-lactams in Escherichia coli and Klebsiella pneumoniae
Comput Struct Biotechnol J, 19, 1896-1906
DOI 10.1016/j.csbj.2021.03.027, PubMed 33897984

Bai X, Zhang J, Hua Y, Jernberg C, Xiong Y, French N, Löfgren S, Hedenström I, Ambikan A, Mernelius S, Matussek A (2021)
Genomic Insights Into Clinical Shiga Toxin-Producing Escherichia coli Strains: A 15-Year Period Survey in Jönköping, Sweden
Front Microbiol, 12, 627861
DOI 10.3389/fmicb.2021.627861, PubMed 33613494

Bjørkto MH, Barratt-Due A, Nordøy I, Dörje C, Galteland E, Lind A, Hilli A, Aukrust P, Mjøen G (2021)
The use of eculizumab in Capnocytophaga canimorsus associated thrombotic microangiopathy: a case report
BMC Infect Dis, 21 (1), 137
DOI 10.1186/s12879-021-05789-2, PubMed 33526010

Borud EK, Nakstad ER, Håberg SE, Lind A, Fadum EA, Taxt AM, Steens A, Gjein GE, Sunde MW, Iversen P, Svanevik M, Ahmad BM, Waldow T, Norheim AJ (2021)
Severe acute respiratory syndrome coronavirus 2 prevalence in 1170 asymptomatic Norwegian conscripts
Health Sci Rep, 4 (1), e233
DOI 10.1002/hsr2.233, PubMed 33490637

Bruun T, Salamanca BV, Bekkevold T, Døllner H, Gibory M, Gilje AM, Haarr E, Kran AB, Leegaard TM, Nakstad B, Nordbø SA, Rojahn A, Størdal K, Flem E, Norwegian Enhanced Pediatric Immunisation Surveillance Network (2021)
Impact of the Rotavirus Vaccination Program in Norway After Four Years With High Coverage
Pediatr Infect Dis J, 40 (4), 368-374
DOI 10.1097/INF.0000000000003020, PubMed 33399430

Helgesen E, Sætre F, Skarstad K (2021)
Topoisomerase IV tracks behind the replication fork and the SeqA complex during DNA replication in Escherichia coli
Sci Rep, 11 (1), 474
DOI 10.1038/s41598-020-80043-4, PubMed 33436807

Hua Y, Chromek M, Frykman A, Jernberg C, Georgieva V, Hansson S, Zhang J, Marits AK, Wan C, Matussek A, Bai X (2021)
Whole-genome characterization of hemolytic uremic syndrome-causing Shiga toxin-producing Escherichia coli in Sweden
Virulence, 12 (1), 1296-1305
DOI 10.1080/21505594.2021.1922010, PubMed 33939581

Hua Y, Zhang J, Jernberg C, Chromek M, Hansson S, Frykman A, Xiong Y, Wan C, Matussek A, Bai X (2021)
Molecular Characterization of the Enterohemolysin Gene (ehxA) in Clinical Shiga Toxin-Producing Escherichia coli Isolates
Toxins (Basel), 13 (1)
DOI 10.3390/toxins13010071, PubMed 33477906

Jiang X, Bergquist A, Löscher BS, Venkatesh G, Mold JE, Holm K, Laerdahl JK, Skånland SS, Maleki KT, Cornillet M, Taskén K, Franke A, Karlsen TH, Björkström NK, Melum E (2021)
A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
Sci Transl Med, 13 (582)
DOI 10.1126/scitranslmed.abb0036, PubMed 33627483

Landaas ET, Storm ML, Tollanes MC, Barlinn R, Kran AMB, Bragstad K, Christensen A, Andreassen T (2021)
Diagnostic performance of a SARS-CoV-2 rapid antigen test in a large, Norwegian cohort
J. Clin. Virol., 137, 104789

Lossius AH, Sundnes O, Ingham AC, Edslev SM, Bjørnholt JV, Lilje B, Bradley M, Asad S, Haraldsen G, Skytt-Andersen P, Holm JØ, Berents TL (2021)
Shifts in the Skin Microbiota after UVB Treatment in Adult Atopic Dermatitis
Dermatology, 1-12 (in press)
DOI 10.1159/000515236, PubMed 33887725

Muller KE, Blomberg B, Tellevik MG, Jensenius M, Fladeby C, Lier T, Sand G, Hannula R, Langeland N, Morch K (2021)
Leishmaniasis in Norway
Tidsskr. Nor. Laegeforen., 141 (3), 250-254

Müller KE, Blomberg B, Tellevik MG, Jensenius M, Fladeby C, Lier T, Sand G, Hannula R, Langeland N, Mørch K (2021)
Leishmaniasis in Norway
Tidsskr Nor Laegeforen, 141 (3)
DOI 10.4045/tidsskr.19.0171, PubMed 33624958

Nesse LL, Mo SS, Ramstad SN, Witsø IL, Sekse C, Bruvoll AEE, Urdahl AM, Vestby LK (2021)
The Effect of Antimicrobial Resistance Plasmids Carrying blaCMY-2 on Biofilm Formation by Escherichia coli from the Broiler Production Chain
Microorganisms, 9 (1)
DOI 10.3390/microorganisms9010104, PubMed 33466318

Norheim AJ, Borud EK, Lind A, Fadum EA, Taxt A, Steens A, Bragstad K, Rein E, Nakstad E (2021)
Pre-screening and preventive quarantine likely explains the low SARS-CoV-2 prevalence among Norwegian conscripts
Scand J Prim Health Care, 39 (1), 31-34
DOI 10.1080/02813432.2021.1880101, PubMed 33544016

Oppen K, Ueland T, Siljan WW, Skadberg Ø, Brede C, Lauritzen T, Aukrust P, Steinsvik T, Husebye E, Michelsen AE, Holter JC, Heggelund L (2021)
Hepcidin and Ferritin Predict Microbial Etiology in Community-Acquired Pneumonia
Open Forum Infect Dis, 8 (4), ofab082
DOI 10.1093/ofid/ofab082, PubMed 33880390

Parmar N, Burrows K, Vornewald PM, Lindholm HT, Zwiggelaar RT, Díez-Sánchez A, Martín-Alonso M, Fosslie M, Vallance BA, Dahl JA, Zaph C, Oudhoff MJ (2021)
Intestinal-epithelial LSD1 controls goblet cell maturation and effector responses required for gut immunity to bacterial and helminth infection
PLoS Pathog, 17 (3), e1009476
DOI 10.1371/journal.ppat.1009476, PubMed 33788902

Quan ZL, Luo CY, Zhu BT, Zhao CG, Yang MY, Bjoras M, Zhu KZ, Kjoniksen AL (2021)
Synthesis and antimicrobial activities of chitosan/polypropylene carbonate-based nanoparticles
RSC Adv., 11 (17), 10121-10129

Roliński M, Montaldo NP, Aksu ME, Fordyce Martin SL, Brambilla A, Kunath N, Johansen J, Erlandsen SE, Liabbak NB, Rian K, Bjørås M, Sætrom P, van Loon B (2021)
Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation
Nucleic Acids Res, 49 (3), 1470-1484
DOI 10.1093/nar/gkaa1289, PubMed 33444446

Sigfrid L, Cevik M, Jesudason E, Lim WS, Rello J, Amuasi J, Bozza F, Palmieri C, Munblit D, Holter JC, Kildal AB, Reyes LF, Russell CD, Ho AT, Turtle L, Drake TM, Beltrame A, Hann K, Bangura IR, Fowler R, Lakoh S, Berry C, Lowe DJ, McPeake J, Hashmi M et al. (2021)
What is the recovery rate and risk of long-term consequences following a diagnosis of COVID-19? A harmonised, global longitudinal observational study protocol
BMJ Open, 11 (3), e043887

Xu KQ, Chatzitakis A, Risbakk S, Yang MY, Backe PH, Grandcolas M, Bjoras M, Norby T (2021)
High performance and toxicity assessment of Ta3N5 nanotubes for photoelectrochemical water splitting
Catal. Today, 361, 57-62

 
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