Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2018 from OUS - Department of Microbiology
35 publications found
Breaking the speed limit with multimode fast scanning of DNA by Endonuclease V
Nat Commun, 9 (1), 5381
DOI 10.1038/s41467-018-07797-4, PubMed 30568191
Excision of the doubly methylated base N4,5-dimethylcytosine from DNA by Escherichia coli Nei and Fpg proteins
Philos Trans R Soc Lond B Biol Sci, 373 (1748)
DOI 10.1098/rstb.2017.0337, PubMed 29685966
A genomic view of experimental intraspecies and interspecies transformation of a rifampicin-resistance allele into Neisseria meningitidis
Microb Genom, 4 (11)
DOI 10.1099/mgen.0.000222, PubMed 30251949
Increased nuclear DNA damage precedes mitochondrial dysfunction in peripheral blood mononuclear cells from Huntington's disease patients
Sci Rep, 8 (1), 9817
DOI 10.1038/s41598-018-27985-y, PubMed 29959348
A transgenic minipig model of Huntington's disease shows early signs of behavioral and molecular pathologies
Dis Model Mech, 11 (10)
DOI 10.1242/dmm.035949, PubMed 30254085
Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity
Mol Cancer, 17 (1), 171
DOI 10.1186/s12943-018-0918-6, PubMed 30526604
Maternal and congenital cytomegalovirus infections in a population-based pregnancy cohort study
APMIS, 126 (12), 899-906
DOI 10.1111/apm.12899, PubMed 30378168
How low can you go? Pushing the limits of low-input ChIP-seq
Brief Funct Genomics, 17 (2), 89-95
DOI 10.1093/bfgp/elx037, PubMed 29087438
The Role of Mitochondrial Dysfunction in the Progression of Alzheimer's Disease
Curr Med Chem, 25 (40), 5578-5587
DOI 10.2174/0929867324666170616110111, PubMed 28618998
Normal development of mice lacking PAXX, the paralogue of XRCC4 and XLF
FEBS Open Bio, 8 (3), 426-434
DOI 10.1002/2211-5463.12381, PubMed 29511619
STIM1 R304W causes muscle degeneration and impaired platelet activation in mice
Cell Calcium, 76, 87-100
DOI 10.1016/j.ceca.2018.10.001, PubMed 30390422
Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
Nucleic Acids Res, 46 (22), 11698-11711
DOI 10.1093/nar/gky846, PubMed 30247619
Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction
Sci Rep, 8 (1), 6725
DOI 10.1038/s41598-018-25168-3, PubMed 29712976
Expression of nucleotide excision repair in Alzheimer's disease is higher in brain tissue than in blood
Neurosci Lett, 672, 53-58
DOI 10.1016/j.neulet.2018.02.043, PubMed 29474873
Transfer of a bla CTX-M-1-carrying plasmid between different Escherichia coli strains within the human gut explored by whole genome sequencing analyses
Sci Rep, 8 (1), 280
DOI 10.1038/s41598-017-18659-2, PubMed 29321570
Influence of acute promyelocytic leukemia therapeutic drugs on nuclear pore complex density and integrity
Biochem Biophys Res Commun, 499 (3), 570-576
DOI 10.1016/j.bbrc.2018.03.191, PubMed 29596829
Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding
Nat Commun, 9 (1), 3665
DOI 10.1038/s41467-018-05578-7, PubMed 30202009
Ythdf2-mediated m6A mRNA clearance modulates neural development in mice
Genome Biol, 19 (1), 69
DOI 10.1186/s13059-018-1436-y, PubMed 29855337
RNA m6A methylation participates in regulation of postnatal development of the mouse cerebellum
Genome Biol, 19 (1), 68
DOI 10.1186/s13059-018-1435-z, PubMed 29855379
Key Residues Affecting Transglycosylation Activity in Family 18 Chitinases: Insights into Donor and Acceptor Subsites
Biochemistry, 57 (29), 4325-4337
DOI 10.1021/acs.biochem.8b00381, PubMed 29939724
Biallelic variants in KIF14 cause intellectual disability with microcephaly
Eur J Hum Genet, 26 (3), 330-339
DOI 10.1038/s41431-017-0088-9, PubMed 29343805
Donor-derived strongyloidiasis after organ transplantation in Norway
Transpl Infect Dis, 21 (1), e13008
DOI 10.1111/tid.13008, PubMed 30295406
An Estimate of the Burden of Fungal Disease in Norway
J Fungi (Basel), 4 (1)
DOI 10.3390/jof4010029, PubMed 29466284
Temporal trends of transmitted HIV drug resistance in a multinational seroconversion cohort
AIDS, 32 (2), 161-169
DOI 10.1097/QAD.0000000000001689, PubMed 29112061
Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments
Mol Psychiatry, 25 (4), 732-749
DOI 10.1038/s41380-018-0226-y, PubMed 30127471
High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections
J Neuroinflammation, 15 (1), 327
DOI 10.1186/s12974-018-1366-3, PubMed 30470234
Neonatal Ogg1/Mutyh knockout mice have altered inflammatory gene response compared to wildtype mice in the brain and lung after hypoxia-reoxygenation
J Perinat Med, 47 (1), 114-124
DOI 10.1515/jpm-2018-0172, PubMed 30020889
Increased Levels of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Ischemic Stroke and Transient Ischemic Attack
J Am Heart Assoc, 7 (2)
DOI 10.1161/JAHA.117.006479, PubMed 29330254
Parental micronutrient deficiency distorts liver DNA methylation and expression of lipid genes associated with a fatty-liver-like phenotype in offspring
Sci Rep, 8 (1), 3055
DOI 10.1038/s41598-018-21211-5, PubMed 29445184
Ultracentrifugation versus kit exosome isolation: nanoLC-MS and other tools reveal similar performance biomarkers, but also contaminations
Future Sci OA, 5 (1), FSO359
DOI 10.4155/fsoa-2018-0088, PubMed 30652024
Serum Uric Acid as an Independent Risk Factor for the Presence and Severity of Early-Onset Coronary Artery Disease: A Case-Control Study
Dis Markers, 2018, 1236837
DOI 10.1155/2018/1236837, PubMed 30425752
Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm
Mol Cell, 71 (6), 973-985.e5
DOI 10.1016/j.molcel.2018.08.011, PubMed 30197295
Stratification by interferon-γ release assay level predicts risk of incident TB
Thorax, 73 (7), 652-661
DOI 10.1136/thoraxjnl-2017-211147, PubMed 29622693
Screening and Identification of Pregnancy Zone Protein and Leucine-Rich Alpha-2-Glycoprotein as Potential Serum Biomarkers for Early-Onset Myocardial Infarction using Protein Profile Analysis
Proteomics Clin Appl, 13 (3), e1800079
DOI 10.1002/prca.201800079, PubMed 30411527
A Systems Approach to Study Immuno- and Neuro-Modulatory Properties of Antiviral Agents
Viruses, 10 (8)
DOI 10.3390/v10080423, PubMed 30103549