Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2021 from OUS - Division of Cancer Medicine

195 publications found

Aas K, Berge V, Myklebust TA, Fossa SD (2021)
Comparative Survival Outcomes of High-risk Prostate Cancer Treated with Radical Prostatectomy or Definitive Radiotherapy Regimens
Eur. Urol. Open Sci., 26, 55-63

Abrahamsen CS, Lang-Ree HM, Halvorsen K, Stenbakken CM (2021)
Patients with COPD: Exploring patients' coping ability during an interdisciplinary pulmonary rehabilitation programme: A qualitative focus group study
J Clin Nurs, 30 (9-10), 1479-1488
DOI 10.1111/jocn.15700, PubMed 33555629

Agudo-Canalejo J, Schultz SW, Chino H, Migliano SM, Saito C, Koyama-Honda I, Stenmark H, Brech A, May AI, Mizushima N, Knorr RL (2021)
Wetting regulates autophagy of phase-separated compartments and the cytosol
Nature, 591 (7848), 142-146
DOI 10.1038/s41586-020-2992-3, PubMed 33473217

Akimov Y, Aittokallio T (2021)
Re-defining synthetic lethality by phenotypic profiling for precision oncology
Cell Chem Biol, 28 (3), 246-256
DOI 10.1016/j.chembiol.2021.01.026, PubMed 33631125

Andersen E, Chollet ME, Sletten M, Stavik B, Skarpen E, Backe PH, Thiede B, Glosli H, Henriksson CE, Iversen N (2021)
Molecular Characterization of Two Homozygous Factor VII Variants Associated with Intracranial Bleeding
Thromb Haemost (in press)
DOI 10.1055/a-1450-8568, PubMed 33742435

ArdeshirRouhaniFard S, Dinh PC, Monahan PO, Fossa SD, Huddart R, Fung C, Song Y, Feldman DR, Hamilton RJ, Vaughn DJ, Martin NE, Kollmannsberger C, Einhorn L, Kroenke K, Travis LB (2021)
Use of Medications for Treating Anxiety or Depression among Testicular Cancer Survivors: A Multi-Institutional Study
Cancer Epidemiol Biomarkers Prev (in press)
DOI 10.1158/1055-9965.EPI-20-1762, PubMed 33849970

Aure MR, Fleischer T, Bjørklund S, Ankill J, Castro-Mondragon JA, OSBREAC, Børresen-Dale AL, Tost J, Sahlberg KK, Mathelier A, Tekpli X, Kristensen VN (2021)
Crosstalk between microRNA expression and DNA methylation drives the hormone-dependent phenotype of breast cancer
Genome Med, 13 (1), 72
DOI 10.1186/s13073-021-00880-4, PubMed 33926515

Autio M, Leivonen SK, Brück O, Mustjoki S, Mészáros Jørgensen J, Karjalainen-Lindsberg ML, Beiske K, Holte H, Pellinen T, Leppä S (2021)
Immune cell constitution in the tumor microenvironment predicts the outcome in diffuse large B-cell lymphoma
Haematologica, 106 (3), 718-729
DOI 10.3324/haematol.2019.243626, PubMed 32079690

Bahadoer RR, Bastiaannet E, Claassen YHM, van der Mark M, van Eycken E, Verbeeck J, Guren MG, Kørner H, Martling A, Johansson R, van de Velde CJH, Dekker JWT (2021)
One-year excess mortality and treatment in surgically treated patients with colorectal cancer: A EURECCA European comparison
Eur J Surg Oncol (in press)
DOI 10.1016/j.ejso.2021.01.011, PubMed 33518367

Balstad TR, Brunelli C, Pettersen CH, Schønberg SA, Skorpen F, Fallon M, Kaasa S, Bye A, Laird BJA, Stene GB, Solheim TS (2021)
Power Comparisons and Clinical Meaning of Outcome Measures in Assessing Treatment Effect in Cancer Cachexia: Secondary Analysis From a Randomized Pilot Multimodal Intervention Trial
Front Nutr, 7, 602775
DOI 10.3389/fnut.2020.602775, PubMed 33585533

Banys-Paluchowski M, Gasparri ML, de Boniface J, Gentilini O, Stickeler E, Hartmann S, Thill M, Rubio IT, Di Micco R, Bonci EA, Niinikoski L, Kontos M, Karadeniz Cakmak G, Hauptmann M, Peintinger F, Pinto D, Matrai Z, Murawa D, Kadayaprath G, Dostalek L, Nina H, Krivorotko P, Classe JM, Schlichting E, Appelgren M et al. (2021)
Surgical Management of the Axilla in Clinically Node-Positive Breast Cancer Patients Converting to Clinical Node Negativity through Neoadjuvant Chemotherapy: Current Status, Knowledge Gaps, and Rationale for the EUBREAST-03 AXSANA Study
Cancers (Basel), 13 (7)
DOI 10.3390/cancers13071565, PubMed 33805367

Barański M, Średnicka-Tober D, Rempelos L, Hasanaliyeva G, Gromadzka-Ostrowska J, Skwarło-Sońta K, Królikowski T, Rembiałkowska E, Hajslova J, Schulzova V, Cakmak I, Ozturk L, Hallmann E, Seal C, Iversen PO, Vigar V, Leifert C (2021)
Feed Composition Differences Resulting from Organic and Conventional Farming Practices Affect Physiological Parameters in Wistar Rats-Results from a Factorial, Two-Generation Dietary Intervention Trial
Nutrients, 13 (2)
DOI 10.3390/nu13020377, PubMed 33530419

Barkovskaya A, Goodwin CM, Seip K, Hilmarsdottir B, Pettersen S, Stalnecker C, Engebraaten O, Briem E, Der CJ, Moestue SA, Gudjonsson T, Maelandsmo GM, Prasmickaite L (2021)
Detection of phenotype-specific therapeutic vulnerabilities in breast cells using a CRISPR loss-of-function screen
Mol Oncol (in press)
DOI 10.1002/1878-0261.12951, PubMed 33759347

Ben-Elazar S, Aure MR, Jonsdottir K, Leivonen SK, Kristensen VN, Janssen EAM, Kleivi Sahlberg K, Lingjærde OC, Yakhini Z (2021)
miRNA normalization enables joint analysis of several datasets to increase sensitivity and to reveal novel miRNAs differentially expressed in breast cancer
PLoS Comput Biol, 17 (2), e1008608
DOI 10.1371/journal.pcbi.1008608, PubMed 33566819

Berg KCG, Brunsell TH, Sveen A, Alagaratnam S, Bjørnslett M, Hektoen M, Brudvik KW, Røsok BI, Bjørnbeth BA, Nesbakken A, Lothe RA (2021)
Genomic and prognostic heterogeneity among RAS/BRAFV600E /TP53 co-mutated resectable colorectal liver metastases
Mol Oncol, 15 (4), 830-845
DOI 10.1002/1878-0261.12885, PubMed 33325154

Berishvili E, Kaiser L, Cohen M, Berney T, Scholz H, Floisand Y, Mattsson J (2021)
Treatment of COVID-19 Pneumonia: the Case for Placenta-derived Cell Therapy
Stem Cell Rev Rep, 17 (1), 63-70
DOI 10.1007/s12015-020-10004-x, PubMed 32696426

Bjerring AW, Fosså SD, Haugnes HS, Nome R, Stokke TM, Haugaa KH, Kiserud CE, Edvardsen T, Sarvari SI (2021)
The cardiac impact of cisplatin-based chemotherapy in survivors of testicular cancer: a 30-year follow-up
Eur Heart J Cardiovasc Imaging, 22 (4), 443-450
DOI 10.1093/ehjci/jeaa289, PubMed 33152065

Bjørkto MH, Barratt-Due A, Nordøy I, Dörje C, Galteland E, Lind A, Hilli A, Aukrust P, Mjøen G (2021)
The use of eculizumab in Capnocytophaga canimorsus associated thrombotic microangiopathy: a case report
BMC Infect Dis, 21 (1), 137
DOI 10.1186/s12879-021-05789-2, PubMed 33526010

Bjørnetrø T, Steffensen LA, Vestad B, Brusletto BS, Olstad OK, Trøseid AM, Aass HCD, Haug KBF, Llorente A, Bøe SO, Lång A, Samiappan R, Redalen KR, Øvstebø R, Ree AH (2021)
Uptake of circulating extracellular vesicles from rectal cancer patients and differential responses by human monocyte cultures
FEBS Open Bio, 11 (3), 724-740
DOI 10.1002/2211-5463.13098, PubMed 33512765

Bøhn SK, Thune I, Flote VG, Frydenberg H, Bertheussen GF, Husøy A, Fjeldheim F, Brunvoll SH, Hjartåker A, Mowinckel MC, Sandset PM, Iversen PO (2021)
Effects of a 1-Year Physical Activity Intervention on Markers of Hemostasis among Breast Cancer Survivors: A Randomized Controlled Trial
TH Open, 5 (1), e14-e23
DOI 10.1055/s-0040-1721782, PubMed 33564742

Bong WK, Gaustadnes LM, Bergland A, Chen W, Bye A (2021)
Community-living older people's interpretation of the Norwegian version of older people's quality of life (OPQOL) questionnaire
Health Soc Care Community
DOI 10.1111/hsc.13273, PubMed 33440057

Bonner ER, Waszak SM, Grotzer MA, Mueller S, Nazarian J (2021)
Mechanisms of imipridones in targeting mitochondrial metabolism in cancer cells
Neuro Oncol, 23 (4), 542-556
DOI 10.1093/neuonc/noaa283, PubMed 33336683

Bonsaksen T, Skogstad L, Grimholt TK, Heir T, Ekeberg O, Lerdal A, Schou-Bredal I (2021)
Substance use in the Norwegian general population: prevalence and associations with disease
J. Subst. Use, 26 (2), 144-150

Boye K, Longhi A, Guren T, Lorenz S, Næss S, Pierini M, Taksdal I, Lobmaier I, Cesari M, Paioli A, Løndalen AM, Setola E, Hompland I, Meza-Zepeda LA, Sundby Hall K, Palmerini E (2021)
Pembrolizumab in advanced osteosarcoma: results of a single-arm, open-label, phase 2 trial
Cancer Immunol Immunother
DOI 10.1007/s00262-021-02876-w, PubMed 33580363

Breast Cancer Association Consortium, Dorling L, Carvalho S, Allen J, González-Neira A, Luccarini C, Wahlström C, Pooley KA, Parsons MT, Fortuno C, Wang Q, Bolla MK, Dennis J, Keeman R, Alonso MR, Álvarez N, Herraez B, Fernandez V, Núñez-Torres R, Osorio A, Valcich J, Li M, Törngren T, Harrington PA, Baynes C et al. (2021)
Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women
N Engl J Med, 384 (5), 428-439
DOI 10.1056/NEJMoa1913948, PubMed 33471991

Brustugun OT, Heggelund L (2021)
COVID-19 vaccination of cancer patients
Tidsskr Nor Laegeforen, 141 (3)
DOI 10.4045/tidsskr.21.0026, PubMed 33624982

Buratta S, Shimanaka Y, Costanzi E, Ni S, Urbanelli L, Kono N, Morena F, Sagini K, Giovagnoli S, Romani R, Gargaro M, Arai H, Emiliani C (2021)
Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells
Sci Rep, 11 (1), 4613
DOI 10.1038/s41598-021-84268-9, PubMed 33633289

Cangiano M, Grudniewska M, Salji MJ, Nykter M, Jenster G, Urbanucci A, Granchi Z, Janssen B, Hamilton G, Leung HY, Beumer IJ (2021)
Gene Regulation Network Analysis on Human Prostate Orthografts Highlights a Potential Role for the JMJD6 Regulon in Clinical Prostate Cancer
Cancers (Basel), 13 (9)
DOI 10.3390/cancers13092094, PubMed 33925994

Carlsen H, Ebihara K, Kuwata NH, Kuwata K, Aydemir G, Rühl R, Blomhoff R (2021)
A transgenic reporter mouse model for in vivo assessment of retinoic acid receptor transcriptional activation
Int J Vitam Nutr Res, 1-13 (in press)
DOI 10.1024/0300-9831/a000705, PubMed 33928787

Caulier B, Enserink JM, Wälchli S (2021)
Pharmacologic Control of CAR T Cells
Int J Mol Sci, 22 (9)
DOI 10.3390/ijms22094320, PubMed 33919245

Cesaro S, Tridello G, Knelange NS, Blijlevens N, Martin M, Snowden JA, Malladi R, Ljungman P, Deconinck E, Gedde-Dahl T, Byrne J, Xhaard A, Chevallier P, Maertens J, Zuckerman T, Lioure B, Petersen E, Cornelissen JJ, Arcese W, Blaise D, Milpied N, Cahn JY, Aljurf M, de Wreede L, Mauro M et al. (2021)
Impact of early candidemia on the long-term outcome of allogeneic hematopoietic stem cell transplant in non-leukemic patients: an outcome analysis on behalf of IDWP-EBMT
Bone Marrow Transplant
DOI 10.1038/s41409-021-01212-1, PubMed 33514919

Choudhury A, Theophanous S, Lønne PI, Samuel R, Guren MG, Berbee M, Brown P, Lilley J, van Soest J, Dekker A, Gilbert A, Malinen E, Wee L, Appelt AL (2021)
Predicting outcomes in anal cancer patients using multi-centre data and distributed learning - A proof-of-concept study
Radiother Oncol, 159, 183-189 (in press)
DOI 10.1016/j.radonc.2021.03.013, PubMed 33753156

Christensen SB, Simonsen HT, Engedal N, Nissen P, Møller JV, Denmeade SR, Isaacs JT (2021)
From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development
Prog Chem Org Nat Prod, 115, 59-114
DOI 10.1007/978-3-030-64853-4_2, PubMed 33797641

Cui XY, Tjønnfjord GE, Kanse SM, Dahm AEA, Iversen N, Myklebust CF, Sun L, Jiang ZX, Ueland T, Campbell JJ, Ho M, Sandset PM (2021)
Tissue factor pathway inhibitor upregulates CXCR7 expression and enhances CXCL12-mediated migration in chronic lymphocytic leukemia
Sci Rep, 11 (1), 5127
DOI 10.1038/s41598-021-84695-8, PubMed 33664415

Cunha ES, Chen X, Sanz-Gaitero M, Mills DJ, Luecke H (2021)
Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 Å resolution
Nat Commun, 12 (1), 230
DOI 10.1038/s41467-020-20485-6, PubMed 33431861

Dahle DO, Skauby M, Langberg CW, Brabrand K, Wessel N, Midtvedt K (2021)
Renal Cell Carcinoma and Kidney Transplantation: A Narrative Review
Transplantation (in press)
DOI 10.1097/TP.0000000000003762, PubMed 33741842

Davidson B, Kleinberg L, Børresen IM, Slettevoll F, Fangberget A, Hindosh D, Zahl Eriksson AG, Bjerkehagen B (2021)
Primary uterine ectomesenchymoma harboring a DICER1 mutation: case report with molecular analysis
Virchows Arch
DOI 10.1007/s00428-021-03057-x, PubMed 33595736

Davydova E, Shimazu T, Schuhmacher MK, Jakobsson ME, Willemen HLDM, Liu T, Moen A, Ho AYY, Małecki J, Schroer L, Pinto R, Suzuki T, Grønsberg IA, Sohtome Y, Akakabe M, Weirich S, Kikuchi M, Olsen JV, Dohmae N, Umehara T, Sodeoka M, Siino V, McDonough MA, Eijkelkamp N, Schofield CJ et al. (2021)
The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes
Nat Commun, 12 (1), 891
DOI 10.1038/s41467-020-20670-7, PubMed 33563959

Dimopoulos MA, Moreau P, Terpos E, Mateos MV, Zweegman S, Cook G, Delforge M, Hájek R, Schjesvold F, Cavo M, Goldschmidt H, Facon T, Einsele H, Boccadoro M, San-Miguel J, Sonneveld P, Mey U (2021)
Multiple Myeloma: EHA-ESMO Clinical Practice Guidelines for Diagnosis, Treatment and Follow-up
Hemasphere, 5 (2), e528
DOI 10.1097/HS9.0000000000000528, PubMed 33554050

Dimopoulos MA, Moreau P, Terpos E, Mateos MV, Zweegman S, Cook G, Delforge M, Hájek R, Schjesvold F, Cavo M, Goldschmidt H, Facon T, Einsele H, Boccadoro M, San-Miguel J, Sonneveld P, Mey U, EHA Guidelines Committee. Electronic address: guidelines@ehaweb.org, ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org (2021)
Multiple myeloma: EHA-ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Ann Oncol, 32 (3), 309-322
DOI 10.1016/j.annonc.2020.11.014, PubMed 33549387

Eide PK, Valnes LM, Lindstrøm EK, Mardal KA, Ringstad G (2021)
Direction and magnitude of cerebrospinal fluid flow vary substantially across central nervous system diseases
Fluids Barriers CNS, 18 (1), 16
DOI 10.1186/s12987-021-00251-6, PubMed 33794929

Eikeland SA, Smeland KB, Mols F, Fagerli UM, Bersvendsen HS, Kiserud CE, Fosså A (2021)
Chemotherapy-induced peripheral neuropathy after modern treatment of Hodgkin's lymphoma; symptom burden and quality of life
Acta Oncol, 1-10 (in press)
DOI 10.1080/0284186X.2021.1917776, PubMed 33905285

Engeseth M, Enden T, Sandset PM, Wik HS (2021)
Predictors of long-term post-thrombotic syndrome following high proximal deep vein thrombosis: a cross-sectional study
Thromb J, 19 (1), 3
DOI 10.1186/s12959-020-00253-8, PubMed 33419441

Fernandes P, Miotto B, Saint-Ruf C, Said M, Barra V, Nähse V, Ravera S, Cappelli E, Naim V (2021)
FANCD2 modulates the mitochondrial stress response to prevent common fragile site instability
Commun Biol, 4 (1), 127
DOI 10.1038/s42003-021-01647-8, PubMed 33514811

Ferreira FA, Helmersen K, Visnovska T, Jørgensen SB, Aamot HV (2021)
Rapid nanopore-based DNA sequencing protocol of antibiotic-resistant bacteria for use in surveillance and outbreak investigation
Microb Genom, 7 (4)
DOI 10.1099/mgen.0.000557, PubMed 33885360

Fleten KG, Eksteen JJ, Mauseth B, Camilio KA, Vasskog T, Sveinbjørnsson B, Rekdal Ø, Mælandsmo GM, Flatmark K (2021)
Oncolytic peptides DTT-205 and DTT-304 induce complete regression and protective immune response in experimental murine colorectal cancer
Sci Rep, 11 (1), 6731
DOI 10.1038/s41598-021-86239-6, PubMed 33762676

Formica M, Storaci AM, Bertolini I, Carminati F, Knævelsrud H, Vaira V, Vaccari T (2021)
V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis
Autophagy, 1-11 (in press)
DOI 10.1080/15548627.2021.1918915, PubMed 33978540

Galili B, Tekpli X, Kristensen VN, Yakhini Z (2021)
Efficient gene expression signature for a breast cancer immuno-subtype
PLoS One, 16 (1), e0245215
DOI 10.1371/journal.pone.0245215, PubMed 33434192

Gaustad JV, Simonsen TG, Hansem LMK, Rofstad EK (2021)
Intravital microscopy of tumor vessel morphology and function using a standard fluorescence microscope
Eur J Nucl Med Mol Imaging
DOI 10.1007/s00259-021-05243-0, PubMed 33606081

Georgiesh T, Namløs HM, Sharma N, Lorenz S, Myklebost O, Bjerkehagen B, Meza-Zepeda LA, Boye K (2021)
Clinical and molecular implications of NAB2-STAT6 fusion variants in solitary fibrous tumour
Pathology (in press)
DOI 10.1016/j.pathol.2020.11.010, PubMed 33745702

Gerdtsson A, Thor A, Grenabo Bergdahl A, Almås B, Håkansson U, Törnblom M, Negaard HFS, Glimelius I, Halvorsen D, Karlsdóttir Á, Sagstuen Haugnes H, Engen Andreassen K, Melsen Larsen S, Holmberg G, Wahlqvist R, Tandstad T, Cohn-Cedermark G, Ståhl O, Kjellman A (2021)
Unilateral or Bilateral Retroperitoneal Lymph Node Dissection in Nonseminoma Patients with Postchemotherapy Residual Tumour? Results from RETROP, a Population-based Mapping Study by the Swedish Norwegian Testicular Cancer Group
Eur Urol Oncol (in press)
DOI 10.1016/j.euo.2021.02.002, PubMed 33750683

Gillessen S, Sauvé N, Collette L, Daugaard G, de Wit R, Albany C, Tryakin A, Fizazi K, Stahl O, Gietema JA, De Giorgi U, Cafferty FH, Hansen AR, Tandstad T, Huddart RA, Necchi A, Sweeney CJ, Garcia-Del-Muro X, Heng DYC, Lorch A, Chovanec M, Winquist E, Grimison P, Feldman DR, Terbuch A et al. (2021)
Predicting Outcomes in Men With Metastatic Nonseminomatous Germ Cell Tumors (NSGCT): Results From the IGCCCG Update Consortium
J Clin Oncol, 39 (14), 1563-1574
DOI 10.1200/JCO.20.03296, PubMed 33822655

Gorgen A, Guttormsen M, Larsen AC, Siem S, Adli E, Edin NFJ, Gjersdal H, Henriksen G, Malinen E, Modamio V, Schoultz B, Sobas PA, Theodossiou TA, Wikne JC (2021)
The Oslo Cyclotron Laboratory
Eur. Phys. J. Plus, 136 (2), 181

Grad I, Hanes R, Ayuda-Duran P, Kuijjer ML, Enserink JM, Meza-Zepeda LA, Myklebost O (2021)
Discovery of novel candidates for anti-liposarcoma therapies by medium-scale high-throughput drug screening
PLoS One, 16 (3), e0248140

Groendahl AR, Skjei Knudtsen I, Huynh BN, Mulstad M, Moe YM, Knuth F, Tomic O, Indahl UG, Torheim T, Dale E, Malinen E, Futsaether CM (2021)
A comparison of methods for fully automatic segmentation of tumors and involved nodes in PET/CT of head and neck cancers
Phys Med Biol, 66 (6), 065012
DOI 10.1088/1361-6560/abe553, PubMed 33666176

Grønberg BH, Killingberg KT, Fløtten Ø, Brustugun OT, Hornslien K, Madebo T, Langer SW, Schytte T, Nyman J, Risum S, Tsakonas G, Engleson J, Halvorsen TO (2021)
High-dose versus standard-dose twice-daily thoracic radiotherapy for patients with limited stage small-cell lung cancer: an open-label, randomised, phase 2 trial
Lancet Oncol, 22 (3), 321-331
DOI 10.1016/S1470-2045(20)30742-7, PubMed 33662285

Grøvik E, Yi D, Iv M, Tong E, Nilsen LB, Latysheva A, Saxhaug C, Jacobsen KD, Helland Å, Emblem KE, Rubin DL, Zaharchuk G (2021)
Handling missing MRI sequences in deep learning segmentation of brain metastases: a multicenter study
NPJ Digit Med, 4 (1), 33
DOI 10.1038/s41746-021-00398-4, PubMed 33619361

Gullhaug A, Hjermstad MJ, Yri O, Svestad JG, Aass N, Johansen S (2021)
Use of radiotherapy in breast cancer patients with brain metastases- a retrospective 11-year single center study
J Med Imaging Radiat Sci (in press)
DOI 10.1016/j.jmir.2021.01.002, PubMed 33549504

Habberstad R, Frøseth TCS, Aass N, Bjerkeset E, Abramova T, Garcia-Alonso E, Caputo M, Rossi R, Boland JW, Brunelli C, Lund JÅ, Kaasa S, Klepstad P (2021)
Clinical predictors for analgesic response to radiotherapy in patients with painful bone metastases
J Pain Symptom Manage (in press)
DOI 10.1016/j.jpainsymman.2021.03.022, PubMed 33794301

Hamfjord J, Guren TK, Glimelius B, Sorbye H, Pfeiffer P, Dajani O, Lingjaerde OC, Tveit KM, Pallisgaard N, Spindler KG, Kure EH (2021)
Clinicopathological factors associated with tumour-specific mutation detection in plasma of patients with RAS- or BRAF-mutated metastatic colorectal cancer
Int J Cancer (in press)
DOI 10.1002/ijc.33672, PubMed 33961700

Hasanaliyeva G, Chatzidimitrou E, Wang J, Baranski M, Volakakis N, Pakos P, Seal C, Rosa EAS, Markellou E, Iversen PO, Vigar V, Willson A, Barkla B, Leifert C, Rempelos L (2021)
Effect of Organic and Conventional Production Methods on Fruit Yield and Nutritional Quality Parameters in Three Traditional Cretan Grape Varieties: Results from a Farm Survey
Foods, 10 (2)
DOI 10.3390/foods10020476, PubMed 33671741

Hauge S, Eek Mariampillai A, Rødland GE, Bay LTE, Landsverk HB, Syljuåsen RG (2021)
Expanding roles of cell cycle checkpoint inhibitors in radiation oncology
Int J Radiat Biol, 1-10 (in press)
DOI 10.1080/09553002.2021.1913529, PubMed 33877959

Helwa R, Gansmo LB, Bjørnslett M, Halle MK, Werner HMJ, Romundstad P, Hveem K, Vatten L, Dørum A, Lønning PE, Knappskog S (2021)
Impact of MDM2 promoter SNP55 (rs2870820) on risk of endometrial and ovarian cancer
Biomarkers, 26 (4), 302-308
DOI 10.1080/1354750X.2021.1891291, PubMed 33645339

Henning MK, Aaløkken TM, Johansen S (2021)
Contrast medium protocols in routine chest CT: a survey study
Acta Radiol, 284185121997111 (in press)
DOI 10.1177/0284185121997111, PubMed 33648351

Hernæs KH, Smeland KB, Fagerli UM, Kiserud CE (2021)
Post-treatment work patterns amongst survivors of lymphoma treated with high-dose chemotherapy with autologous stem-cell transplantation
BMC Cancer, 21 (1), 143
DOI 10.1186/s12885-021-07836-2, PubMed 33557789

Hernes E, Revheim ME, Hole KH, Tulipan AJ, Strømme H, Lilleby W, Seierstad T (2021)
Prostate-Specific Membrane Antigen PET for Assessment of Primary and Recurrent Prostate Cancer with Histopathology as Reference Standard: A Systematic Review and Meta-Analysis
PET Clin, 16 (2), 147-165
DOI 10.1016/j.cpet.2020.12.001, PubMed 33648661

Herring S, Oda JM, Wagoner J, Kirchmeier D, O'Connor A, Nelson EA, Huang Q, Liang Y, DeWald LE, Johansen LM, Glass PJ, Olinger GG, Ianevski A, Aittokallio T, Paine MF, Fink SL, White JM, Polyak SJ (2021)
Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs
Antimicrob Agents Chemother, 65 (4)
DOI 10.1128/AAC.01146-20, PubMed 33468464

Høghaug G, Skår R, Tran TN, Diep LM, Bredal IS (2021)
Three-month follow-up effects of a medication management program on nurses' knowledge
Nurse Educ Pract, 51, 102979
DOI 10.1016/j.nepr.2021.102979, PubMed 33588183

Holland P, Hagopian WM, Jahren AH, Rusten TE (2021)
Natural abundance isotope ratios to differentiate sources of carbon used during tumor growth in vivo
BMC Biol, 19 (1), 85
DOI 10.1186/s12915-021-01012-5, PubMed 33966633

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Integrating Anatomical, Molecular and Clinical Risk Factors in Gastrointestinal Stromal Tumor of the Stomach
Ann Surg Oncol
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Hompland T, Fjeldbo CS, Lyng H (2021)
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Cancers (Basel), 13 (3)
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True and Missed Interval Cancer in Organized Mammographic Screening: A Retrospective Review Study of Diagnostic and Prior Screening Mammograms
Acad Radiol (in press)
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Hugenschmidt H, Labori KJ, Borgen E, Brunborg C, Schirmer CB, Seeberg LT, Naume B, Wiedswang G (2021)
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Iglesias R, Ferreras JM, Llorente A, Citores L (2021)
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Id2 Represses Aldosterone-Stimulated Cardiac T-Type Calcium Channels Expression
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Janiszewska M, Stein S, Metzger Filho O, Eng J, Kingston NL, Harper NW, Rye IH, Alečković M, Trinh A, Murphy KC, Marangoni E, Cristea S, Oakes B, Winer EP, Krop I, Russnes HG, Spellman PT, Bucher E, Hu Z, Chin K, Gray JW, Michor F, Polyak K (2021)
The impact of tumor epithelial and microenvironmental heterogeneity on treatment responses in HER2-positive breast cancer
JCI Insight (in press)
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Jiang X, Bergquist A, Löscher BS, Venkatesh G, Mold JE, Holm K, Laerdahl JK, Skånland SS, Maleki KT, Cornillet M, Taskén K, Franke A, Karlsen TH, Björkström NK, Melum E (2021)
A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
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Johannesen TB, Smeland S, Aaserud S, Buanes EA, Skog A, Ursin G, Helland Å (2021)
COVID-19 in Cancer Patients, Risk Factors for Disease and Adverse Outcome, a Population-Based Study From Norway
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Rovalpituzumab Tesirine as a Maintenance Therapy After First-Line Platinum-Based Chemotherapy in Patients With Extensive-Stage-SCLC: Results From the Phase 3 MERU Study
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Juzeniene A, Stenberg VY, Bruland ØS, Larsen RH (2021)
Preclinical and Clinical Status of PSMA-Targeted Alpha Therapy for Metastatic Castration-Resistant Prostate Cancer
Cancers (Basel), 13 (4)
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Kargo AS, Jensen PT, Lindemann K, Hjollund NHI, Lund B, Haee M, Möller S, Hansen DG, Dahl Steffensen K (2021)
The PROMova study comparing active and passive use of patient-reported outcome measures in ovarian cancer follow-up: effect on patient-perceived involvement, satisfaction with care, and usefulness
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Kaufman JL, Gasparetto C, Schjesvold FH, Moreau P, Touzeau C, Facon T, Boise LH, Jiang Y, Yang X, Dunbar F, Vishwamitra D, Unger S, Macartney T, Pesko J, Yu Y, Salem AH, Ross JA, Hong WJ, Maciag PC, Pauff JM, Kumar S (2021)
Targeting BCL-2 with venetoclax and dexamethasone in patients with relapsed/refractory t(11;14) multiple myeloma
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Analysing the attributes of Comprehensive Cancer Centres and Cancer Centres across Europe to identify key hallmarks
Mol. Oncol., 15 (5), 1277-1288

Kharfan-Dabaja MA, Labopin M, Bazarbachi A, Ciceri F, Finke J, Bruno B, Bornhäuser M, Gedde-Dahl T, Labussière-Wallet H, Niittyvuopio R, Valerius T, Angelucci E, Brecht A, Caballero D, Kuball J, Potter V, Schmid C, Tischer J, Zuckerman T, Benedetti F, Blaise D, Diez-Martin JL, Sanz J, Ruggeri A, Brissot E et al. (2021)
Comparing outcomes of a second allogeneic hematopoietic cell transplant using HLA-matched unrelated versus T-cell replete haploidentical donors in relapsed acute lymphoblastic leukemia: a study of the Acute Leukemia Working Party of EBMT
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Kihlberg K, Baghaei F, Bruzelius M, Funding E, Andre Holme P, Lassila R, Nummi V, Ranta S, Osooli M, Berntorp E, Astermark J (2021)
Treatment outcomes in persons with severe haemophilia B in the Nordic region: The B-NORD study
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Early detection of complications in pancreas transplants by microdialysis catheters, an observational feasibility study
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Kleppe A, Skrede OJ, De Raedt S, Liestøl K, Kerr DJ, Danielsen HE (2021)
Designing deep learning studies in cancer diagnostics
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Assessment of Waldeyer's ring in pediatric and adolescent Hodgkin lymphoma patients-Importance of multimodality imaging: Results from the EuroNet-PHL-C1 trial
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Dose Reduction of Preoperative Radiotherapy in Myxoid Liposarcoma: A Nonrandomized Controlled Trial
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The HILUS-Trial-a Prospective Nordic Multicenter Phase 2 Study of Ultracentral Lung Tumors Treated With Stereotactic Body Radiotherapy
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Salvage Radiation for Pelvic Relapse after Surgically Treated Endometrial Cancer
Cancers (Basel), 13 (6)
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Nutrition in Cancer Care: A Brief, Practical Guide With a Focus on Clinical Practice
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Liu MS, Zhao H, Xu CX, Xie PB, Wang W, Yang YY, Lee WH, Jin Y, Zhou HQ (2021)
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Phosphoproteomics-Based Characterization of Prostaglandin E2 Signaling in T Cells
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Löwenberg B, Pabst T, Maertens J, Gradowska P, Biemond BJ, Spertini O, Vellenga E, Griskevicius L, Tick LW, Jongen-Lavrencic M, van Marwijk Kooy M, Vekemans MC, van der Velden WJFM, Beverloo B, Michaux L, Graux C, Deeren D, de Weerdt O, van Esser JWJ, Bargetzi M, Klein SK, Gadisseur A, Westerweel PE, Veelken H, Gregor M et al. (2021)
Addition of lenalidomide to intensive treatment in younger and middle-aged adults with newly diagnosed AML: the HOVON-SAKK-132 trial
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Luna S, Torices L, Mingo J, Amo L, Rodríguez-Escudero I, Ruiz-Ibarlucea P, Erramuzpe A, Cortés JM, Tejada MI, Molina M, Nunes-Xavier CE, López JI, Cid VJ, Pulido R (2021)
A global analysis of the reconstitution of PTEN function by translational readthrough of PTEN pathogenic premature termination codons
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Omics analyses in peritoneal metastasis-utility in the management of peritoneal metastases from colorectal cancer and pseudomyxoma peritonei: a narrative review
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Lundar T, Due-Tønnessen BJ, Frič R, Sundseth J, Brandal P, Due-Tønnessen P (2021)
Outcome After Treatment of Spinal Ependymoma in Children and Adolescents: Long-Term Follow-up of a Single Consecutive Institutional Series of 33 Patients Treated Over Eight Decades
World Neurosurg (in press)
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Maagdenberg H, Oosterom N, Zanen J, Gemmati D, Windsor RE, Heil SG, Esperón P, Jabeen S, Ruiz-Argüelles GJ, Zolk O, Hoerning S, Sleurs C, Lopéz-Lopéz E, Moreno-Galván M, van den Heuvel-Eibrink MM, Maitland-van der Zee AH, Carleton BC (2021)
Genetic variants associated with methotrexate-induced mucositis in cancer treatment: A systematic review and meta-analysis
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Måseide RJ, Berntorp E, Astermark J, Hansen J, Olsson A, Bruzelius M, Frisk T, Aspdahl M, Nummi V, Tjønnfjord GE, Holme PA (2021)
Haemophilia early arthropathy detection with ultrasound and haemophilia joint health score in the moderate haemophilia (MoHem) study
Haemophilia, 27 (2), e253-e259
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Maura F, Boyle EM, Rustad EH, Ashby C, Kaminetzky D, Bruno B, Braunstein M, Bauer M, Blaney P, Wang Y, Ghamlouch H, Williams L, Stoeckle J, Davies FE, Walker BA, Maclachlan K, Diamond B, Landgren O, Morgan GJ (2021)
Chromothripsis as a pathogenic driver of multiple myeloma
Semin Cell Dev Biol (in press)
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Meltzer S, Torgunrud A, Abrahamsson H, Solbakken AM, Flatmark K, Dueland S, Bakke KM, Bousquet PA, Negård A, Johansen C, Lyckander LG, Larsen FO, Schou JV, Redalen KR, Ree AH (2021)
The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer
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Mester S, Evers M, Meyer S, Nilsen J, Greiff V, Sandlie I, Leusen J, Andersen JT (2021)
Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo
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Mirlashari MR, Vetlesen A, Nissen-Meyer LSH, Naper C, Tjønnfjord GE, Njerve IU, Ezligini F, Landmark BF, Meinke S, Sandgren P, Höglund P, Hetland G (2021)
HLA class I depletion by citric acid, and irradiation of apheresis platelets for transfusion of refractory patients
Transfusion, 61 (4), 1222-1234
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Moe YM, Groendahl AR, Tomic O, Dale E, Malinen E, Futsaether CM (2021)
Deep learning-based auto-delineation of gross tumour volumes and involved nodes in PET/CT images of head and neck cancer patients
Eur J Nucl Med Mol Imaging
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Moreau P, Kumar SK, San Miguel J, Davies F, Zamagni E, Bahlis N, Ludwig H, Mikhael J, Terpos E, Schjesvold F, Martin T, Yong K, Durie BGM, Facon T, Jurczyszyn A, Sidana S, Raje N, van de Donk N, Lonial S, Cavo M, Kristinsson SY, Lentzsch S, Hajek R, Anderson KC, João C et al. (2021)
Treatment of relapsed and refractory multiple myeloma: recommendations from the International Myeloma Working Group
Lancet Oncol, 22 (3), e105-e118
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Morra A, Jung AY, Behrens S, Keeman R, Ahearn TU, Anton-Culver H, Arndt V, Augustinsson A, Auvinen PK, Beane Freeman LE, Becher H, Beckmann MW, Blomqvist C, Bojesen SE, Bolla MK, Brenner H, Briceno I, Brucker SY, Camp NJ, Campa D, Canzian F, Castelao JE, Chanock SJ, Choi JY, Clarke CL et al. (2021)
Breast Cancer Risk Factors and Survival by Tumor Subtype: Pooled Analyses from the Breast Cancer Association Consortium
Cancer Epidemiol Biomarkers Prev, 30 (4), 623-642
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Mul J, Melchior P, Seravalli E, Saunders D, Bolle S, Cameron AL, Gurtner K, Harrabi S, Lassen-Ramshad Y, Lavan N, Magelssen H, Mandeville H, Boterberg T, Kroon PS, Kotte ANTJ, Hoeben BAW, van Rossum PSN, van Grotel M, Graf N, van den Heuvel-Eibrink MM, Rübe C, Janssens GO (2021)
Inter-clinician delineation variation for a new highly-conformal flank target volume in children with renal tumors: A SIOP-Renal Tumor Study Group international multicenter exercise
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Napoli E, Bønsdorff TB, Jorstad IS, Bruland ØS, Larsen RH, Westrøm S (2021)
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Ngari MM, Obiero C, Mwangome MK, Nyaguara A, Mturi N, Murunga S, Otiende M, Iversen PO, Fegan GW, Walson JL, Berkley JA (2021)
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Otterhaug T, Janetzki S, Welters MJP, Håkerud M, Nedberg AG, Edwards VT, Boekestijn S, Loof NM, Selbo PK, Olivecrona H, van der Burg SH, Høgset A (2021)
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Front Immunol, 11, 576756
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Panagopoulos I, Andersen K, Eilert-Olsen M, Rognlien AG, Munthe-Kaas MC, Micci F, Heim S (2021)
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Panagopoulos I, Andersen K, Eilert-Olsen M, Zeller B, Munthe-Kaas MC, Buechner J, Osnes LTN, Micci F, Heim S (2021)
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Cancer Genomics Proteomics, 18 (1), 67-81
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Panagopoulos I, Andersen K, Ramslien LF, Ikonomou IM, Micci F, Heim S (2021)
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Cancer Genomics Proteomics, 18 (3), 167-196
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Pandya AD, Iversen TG, Moestue S, Grinde MT, Mørch Ý, Snipstad S, Åslund AKO, Øy GF, Kildal W, Engebråten O, Sandvig K, Skotland T, Mælandsmo GM (2021)
Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft
Nanomaterials (Basel), 11 (5)
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Paulsen MM, Varsi C, Andersen LF (2021)
Process evaluation of the implementation of a decision support system to prevent and treat disease-related malnutrition in a hospital setting
BMC Health Serv Res, 21 (1), 281
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Pihlstrøm N, Jin Y, Nenseth Z, Kuzu OF, Saatcioglu F (2021)
STAMP2 Expression Mediated by Cytokines Attenuates Their Growth-Limiting Effects in Prostate Cancer Cells
Cancers (Basel), 13 (7)
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Pommergaard HC, Nielsen K, Sorbye H, Federspiel B, Tabaksblat EM, Vestermark LW, Janson ET, Hansen CP, Ladekarl M, Garresori H, Hjortland GO, Sundlöv A, Galleberg R, Knigge P, Kjaer A, Langer SW, Knigge U (2021)
Surgery of the primary tumour in 201 patients with high-grade gastroenteropancreatic neuroendocrine and mixed neuroendocrine-non-neuroendocrine neoplasms
J Neuroendocrinol, e12967
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Popperud TH, Gul KA, Brunborg C, Olaussen RW, Abrahamsen TG, Osnes LT, Kerty E (2021)
Thymectomy in Juvenile Myasthenia Gravis Is Safe Regarding Long Term Immunological Effects
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Pötter R, Tanderup K, Schmid MP, Jürgenliemk-Schulz I, Haie-Meder C, Fokdal LU, Sturdza AE, Hoskin P, Mahantshetty U, Segedin B, Bruheim K, Huang F, Rai B, Cooper R, van der Steen-Banasik E, Van Limbergen E, Pieters BR, Tan LT, Nout RA, De Leeuw AAC, Ristl R, Petric P, Nesvacil N, Kirchheiner K, Kirisits C et al. (2021)
MRI-guided adaptive brachytherapy in locally advanced cervical cancer (EMBRACE-I): a multicentre prospective cohort study
Lancet Oncol, 22 (4), 538-547
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Prasad PJR, Survarachakan S, Khan ZA, Lindseth F, Elle OJ, Albregtsen F, Kumar RP (2021)
Numerical Evaluation on Parametric Choices Influencing Segmentation Results in Radiology Images-A Multi-Dataset Study
Electronics, 10 (4), 431

Ramberg H, Richardsen E, de Souza GA, Rakaee M, Stensland ME, Braadland PR, Nygård S, Ögren O, Guldvik IJ, Berge V, Svindland A, Taskén KA, Andersen S (2021)
Proteomic analyses Identify Major Vault Protein as a Prognostic Biomarker for Fatal Prostate Cancer
Carcinogenesis (in press)
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Ramis-Zaldivar JE, Gonzalez-Farre B, Nicolae A, Pack S, Clot G, Nadeu F, Mottok A, Horn H, Song JY, Fu K, Wright G, Gascoyne RD, Chan WC, Scott DW, Feldman AL, Valera A, Enjuanes A, Braziel RM, Smeland EB, Staudt LM, Rosenwald A, Rimsza LM, Ott G, Jaffe ES, Salaverria I et al. (2021)
MAP-kinase and JAK-STAT pathways dysregulation in plasmablastic lymphoma
Haematologica (in press)
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Ravussin A, Brech A, Tooze SA, Stenmark H (2021)
The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy
J Cell Sci, 134 (3)
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Reding MT, Pabinger I, Holme PA, Poulsen L, Negrier C, Chalasani P, Maas Enriquez M, Wang M, Meijer K, Mancuso ME, Lalezari S (2021)
Confirmed long-term safety and efficacy of prophylactic treatment with BAY 94-9027 in severe haemophilia A: final results of the PROTECT VIII extension study
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Ree AH (2021)
Precision cancer medicine - still expedient for the few
Tidsskr Nor Laegeforen, 141 (5)
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Reich M, Spomer L, Klindt C, Fuchs K, Stindt J, Deutschmann K, Höhne J, Liaskou E, Hov JR, Karlsen TH, Beuers U, Verheij J, Ferreira-Gonzalez S, Hirschfield G, Forbes SJ, Schramm C, Esposito I, Nierhoff D, Fickert P, Fuchs CD, Trauner M, García-Beccaria M, Gabernet G, Nahnsen S, Mallm JP et al. (2021)
Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis
J Hepatol (in press)
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Remberger M, Tjønnfjord GE, Abrahamsen IW, Ali M, Myhre AE, Gedde-Dahl T, Fløisand Y (2021)
Superior Graft-versus-Host Disease-Free Relapse-Free Survival in Matched Unrelated Donor Hematopoietic Stem Cell Transplantation with Anti-Thymocyte Globulin (ATG) Compared to Matched Related Donor without ATG
Transplant Cell Ther (in press)
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Rodrigues AM, Romeu JC, Canas da Silva J, Tavares-Costa J, Faustino A, Vaz C, Pereira da Silva JA, Canhão H (2021)
Osteoporosis management during the COVID-19 pandemic - Position paper
Acta Reumatol Port, 46 (1), 55-57
PubMed 33820898

Rodrigues JM, Nikkarinen A, Hollander P, Weibull CE, Räty R, Kolstad A, Amini RM, Porwit A, Jerkeman M, Ek S, Glimelius I (2021)
Infiltration of CD163-, PD-L1- and FoxP3-positive cells adversely affects outcome in patients with mantle cell lymphoma independent of established risk factors
Br J Haematol, 193 (3), 520-531
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Rodríguez-Borjabad C, Narveud I, Christensen JJ, Ulven SM, Malo AI, Ibarretxe D, Girona J, Torvik K, Bogsrud MP, Retterstøl K, Plana N, Masana L, Holven KB (2021)
Dietary intake and lipid levels in Norwegian and Spanish children with familial hypercholesterolemia
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Røen I, Brenne AT, Brunelli C, Stifoss-Hanssen H, Grande G, Solheim TS, Kaasa S, Knudsen AK (2021)
Spiritual quality of life in family carers of patients with advanced cancer-a cross-sectional study
Support Care Cancer
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Rustad EH, Nadeu F, Angelopoulos N, Ziccheddu B, Bolli N, Puente XS, Campo E, Landgren O, Maura F (2021)
mmsig: a fitting approach to accurately identify somatic mutational signatures in hematological malignancies
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Schjesvold FH, Richardson PG, Facon T, Alegre A, Spencer A, Jurczyszyn A, Sunami K, Frenzel L, Min CK, Guillonneau S, Lin PL, Le-Guennec S, Campana F, van de Velde H, Bensfia S, Bringhen S (2021)
Isatuximab plus pomalidomide and dexamethasone in elderly patients with relapsed/refractory multiple myeloma: ICARIA-MM subgroup analysis
Haematologica, 106 (4), 1182-1187
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Schläfli AM, Tokarchuk I, Parejo S, Jutzi S, Berezowska S, Engedal N, Tschan MP (2021)
ALK inhibition activates LC3B-independent, protective autophagy in EML4-ALK positive lung cancer cells
Sci Rep, 11 (1), 9011
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Schou-Bredal I, Grimholt T, Bonsaksen T, Skogstad L, Heir T, Ekeberg O (2021)
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Schultz NH, Sørvoll IH, Michelsen AE, Munthe LA, Lund-Johansen F, Ahlen MT, Wiedmann M, Aamodt AH, Skattør TH, Tjønnfjord GE, Holme PA (2021)
Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination
N Engl J Med
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Seierstad T, Hole KH, Tulipan AJ, Strømme H, Lilleby W, Revheim ME, Hernes E (2021)
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Seppälä TT, Dominguez-Valentin M, Crosbie EJ, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W et al. (2021)
Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
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Sharma A, Colonna G (2021)
System-Wide Pollution of Biomedical Data: Consequence of the Search for Hub Genes of Hepatocellular Carcinoma Without Spatiotemporal Consideration
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Shkodra M, Brunelli C, Zecca E, Formaglio F, Bracchi P, Lo Dico S, Caputo M, Kaasa S, Caraceni A (2021)
Neuropathic pain: clinical classification and assessment in patients with pain due to cancer
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Siddiqui FA, Parkkola H, Vukic V, Oetken-Lindholm C, Jaiswal A, Kiriazis A, Pavic K, Aittokallio T, Salminen TA, Abankwa D (2021)
Novel Small Molecule Hsp90/Cdc37 Interface Inhibitors Indirectly Target K-Ras-Signaling
Cancers (Basel), 13 (4)
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Reducing the immunosuppressive tumor microenvironment enhances photoimmunotherapy efficacy
EBioMedicine, 67, 103351 (in press)
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RNA Interference: Story and Mechanisms
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Skaga E, Skretteberg MA, Johannesen TB, Brandal P, Vik-Mo EO, Helseth E, Langmoen IA (2021)
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Skalleberg J, Myhrum M, Småstuen MC, Osnes TA, Fosså SD, Bunne M (2021)
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Acta Oncol, 60 (4), 426-433
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Overcoming resistance to targeted therapies in chronic lymphocytic leukemia
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Skorstad M, de Rooij BH, Jeppesen MM, Bergholdt SH, Ezendam NPM, Bohlin T, Jensen PT, Lindemann K, van de Poll L, Vistad I (2021)
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Int J Gynecol Cancer (in press)
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Slørdahl KS, Klotz D, Olsen JÅ, Skovlund E, Undseth C, Abildgaard HL, Brændengen M, Nesbakken A, Larsen SG, Hanekamp BA, Holmboe L, Tvedt R, Sveen A, Lothe RA, Malinen E, Kaasa S, Guren MG (2021)
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Solis N, Zavaleta E, Wernhoff P, Dominguez-Barrera C, Dominguez-Valentin M (2021)
Challenges to Bringing Personalized Medicine to a Low-Resource Setting in Peru
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Spampinato S, Fokdal LU, Pötter R, Haie-Meder C, Lindegaard JC, Schmid MP, Sturdza A, Jürgenliemk-Schulz IM, Mahantshetty U, Segedin B, Bruheim K, Hoskin P, Rai B, Huang F, Cooper R, van der Steen-Banasik E, Van Limbergen E, Sundset M, Westerveld H, Nout RA, Jensen NBK, Kirisits C, Kirchheiner K, Tanderup K, EMBRACE Collaborative Group (2021)
Risk factors and dose-effects for bladder fistula, bleeding and cystitis after radiotherapy with imaged-guided adaptive brachytherapy for cervical cancer: An EMBRACE analysis
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Spicer J, Marabelle A, Baurain JF, Jebsen NL, Jøssang DE, Awada A, Kristeleit R, Loirat D, Lazaridis G, Jungels C, Brunsvig P, Nicolaisen B, Saunders A, Patel H, Galon J, Hermitte F, Camilio KA, Mauseth B, Sundvold V, Sveinbjørnsson B, Rekdal Ø (2021)
Safety, Antitumor Activity, and T-cell Responses in a Dose-Ranging Phase I Trial of the Oncolytic Peptide LTX-315 in Patients with Solid Tumors
Clin Cancer Res (in press)
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Stabell M, Sæther T, Røhr ÅK, Gabrielsen OS, Myklebost O (2021)
Methylation-dependent SUMOylation of the architectural transcription factor HMGA2
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Stacchiotti S, Frezza AM, Blay JY, Baldini EH, Bonvalot S, Bovée JVMG, Callegaro D, Casali PG, Chiang RC, Demetri GD, Demicco EG, Desai J, Eriksson M, Gelderblom H, George S, Gounder MM, Gronchi A, Gupta A, Haas RL, Hayes-Jardon A, Hohenberger P, Jones KB, Jones RL, Kasper B, Kawai A et al. (2021)
Ultra-rare sarcomas: A consensus paper from the Connective Tissue Oncology Society community of experts on the incidence threshold and the list of entities
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Stjepanovic N, Lubinski J, Moller P, Randall Armel S, Foulkes WD, Tung N, Neuhausen SL, Kotsopoulos J, Sun P, Sun S, Eisen A, Narod SA, Hereditary Breast Cancer Clinical Study Group (2021)
Breast cancer risk after age 60 among BRCA1 and BRCA2 mutation carriers
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Strømmen K, Lyche JL, Moltu SJ, Müller MHB, Blakstad EW, Almaas AN, Sakhi AK, Thomsen C, Nakstad B, Rønnestad AE, Drevon CA, Iversen PO (2021)
High urinary concentrations of parabens and bisphenol A in very low birth weight infants
Chemosphere, 271, 129570
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Sullivan LC, Nguyen THO, Harpur CM, Stankovic S, Kanagarajah AR, Koutsakos M, Saunders PM, Cai Z, Gray JA, Widjaja JML, Lin J, Pietra G, Mingari MC, Moretta L, Samir J, Luciani F, Westall GP, Malmberg KJ, Kedzierska K, Brooks AG (2021)
Natural killer cell receptors regulate responses of HLA-E-restricted T cells
Sci Immunol, 6 (58)
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Tabernero J, Grothey A, Van Cutsem E, Yaeger R, Wasan H, Yoshino T, Desai J, Ciardiello F, Loupakis F, Hong YS, Steeghs N, Guren TK, Arkenau HT, Garcia-Alfonso P, Elez E, Gollerkeri A, Maharry K, Christy-Bittel J, Kopetz S (2021)
Encorafenib Plus Cetuximab as a New Standard of Care for Previously Treated BRAF V600E-Mutant Metastatic Colorectal Cancer: Updated Survival Results and Subgroup Analyses from the BEACON Study
J Clin Oncol, 39 (4), 273-284
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Tanoli Z, Vähä-Koskela M, Aittokallio T (2021)
Artificial intelligence, machine learning, and drug repurposing in cancer
Expert Opin Drug Discov
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Terkelsen T, Pernemalm M, Gromov P, Børresen-Dale AL, Krogh A, Haakensen VD, Lethiö J, Papaleo E, Gromova I (2021)
High-throughput proteomics of breast cancer interstitial fluid: identification of tumor subtype-specific serologically relevant biomarkers
Mol Oncol, 15 (2), 429-461
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Terpos E, Zamagni E, Lentzsch S, Drake MT, García-Sanz R, Abildgaard N, Ntanasis-Stathopoulos I, Schjesvold F, de la Rubia J, Kyriakou C, Hillengass J, Zweegman S, Cavo M, Moreau P, San-Miguel J, Dimopoulos MA, Munshi N, Durie BGM, Raje N, Bone Working Group of the International Myeloma Working Group (2021)
Treatment of multiple myeloma-related bone disease: recommendations from the Bone Working Group of the International Myeloma Working Group
Lancet Oncol, 22 (3), e119-e130
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Thorgersen EB, Flatmark K (2021)
ASO Author Reflections: The Peritoneum is an Active Immunological Compartment
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Torices L, de Las Heras J, Arango-Lasprilla JC, Cortés JM, Nunes-Xavier CE, Pulido R (2021)
MMADHC premature termination codons in the pathogenesis of cobalamin D disorder: Potential of translational readthrough reconstitution
Mol Genet Metab Rep, 26, 100710
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Vajavaara H, Ekeblad F, Holte H, Jorgensen J, Leivonen SK, Berglund M, Kamper P, Moller HJ, D'Amore F, Molin D, Enblad G, Ludvigsen M, Glimelius I, Leppa S (2021)
Prognostic impact of soluble CD163 in patients with diffuse large Bcell lymphoma
Haematologica (in press)
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Vajavaara H, Mortensen JB, Leivonen SK, Hansen IM, Ludvigsen M, Holte H, Jørgensen J, Bjerre M, d'Amore F, Leppä S (2021)
Soluble PD-1 but Not PD-L1 Levels Predict Poor Outcome in Patients with High-Risk Diffuse Large B-Cell Lymphoma
Cancers (Basel), 13 (3)
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Valsalakumari R, Yadava SK, Szwed M, Pandya AD, Mælandsmo GM, Torgersen ML, Iversen TG, Skotland T, Sandvig K, Giri J (2021)
Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells
Int J Pharm, 597, 120217
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van den Berg MH, van Dijk M, Byrne J, Berger C, Dirksen U, Winther JF, Fossa SD, Grabow D, Grandage VL, Haupt R, van den Heuvel-Eibrink MM, Kaiser M, Kepak T, van der Kooi ALF, Kremer LCM, Kruseova J, Lambalk CB, van Leeuwen FE, Leiper A, Modan-Moses D, Spix C, Twisk JWR, Ronckers CM, Kaatsch P, van Dulmen-den Broeder E et al. (2021)
Treatment-related fertility impairment in long-term female childhood, adolescent and young adult cancer survivors: investigating dose-effect relationships in a European case-control study (PanCareLIFE)
Hum Reprod (in press)
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van der Kooi ALF, van Dijk M, Broer L, van den Berg MH, Laven JSE, van Leeuwen FE, Lambalk CB, Overbeek A, Loonen JJ, van der Pal HJ, Tissing WJ, Versluys B, Bresters D, Beerendonk CCM, Ronckers CR, van der Heiden-van der Loo M, Kaspers GL, de Vries ACH, Robison LL, Hudson MM, Chemaitilly W, Byrne J, Berger C, Clemens E, Dirksen U et al. (2021)
Possible modification of BRSK1 on the risk of alkylating chemotherapy-related reduced ovarian function
Hum Reprod, 36 (4), 1120-1133
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Wang J, Barański M, Hasanaliyeva G, Korkut R, Kalee HA, Leifert A, Winter S, Janovska D, Willson A, Barkla B, Iversen PO, Seal C, Bilsborrow P, Leifert C, Rempelos L, Volakakis N (2021)
Effect of irrigation, fertiliser type and variety on grain yield and nutritional quality of spelt wheat (Triticum spelta) grown under semi-arid conditions
Food Chem, 358, 129826 (in press)
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Weider T, Richardson SJ, Morgan NG, Paulsen TH, Dahl-Jørgensen K, Hammerstad SS (2021)
HLA Class I Upregulation and Antiviral Immune Responses in Graves Disease
J Clin Endocrinol Metab, 106 (4), e1763-e1774
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Westgaard KL, Hynne H, Amdal CD, Young A, Singh PB, Chen X, Rykke M, Hove LH, Aqrawi LA, Utheim TP, Herlofson BB, Jensen JL (2021)
Oral and ocular late effects in head and neck cancer patients treated with radiotherapy
Sci Rep, 11 (1), 4026
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Wirth M, Mouilleron S, Zhang W, Sjøttem E, Princely Abudu Y, Jain A, Lauritz Olsvik H, Bruun JA, Razi M, Jefferies HBJ, Lee R, Joshi D, O'Reilly N, Johansen T, Tooze SA (2021)
Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity
J Mol Biol, 433 (13), 166987 (in press)
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Yap TA, Nakagawa K, Fujimoto N, Kuribayashi K, Guren TK, Calabrò L, Shapira-Frommer R, Gao B, Kao S, Matos I, Planchard D, Chatterjee A, Jin F, Norwood K, Kindler HL (2021)
Efficacy and safety of pembrolizumab in patients with advanced mesothelioma in the open-label, single-arm, phase 2 KEYNOTE-158 study
Lancet Respir Med (in press)
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Zanca F, Hernandez-Giron I, Avanzo M, Guidi G, Crijns W, Diaz O, Kagadis GC, Rampado O, Lønne PI, Ken S, Colgan N, Zaidi H, Zakaria GA, Kortesniemi M (2021)
Expanding the medical physicist curricular and professional programme to include Artificial Intelligence
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Zhen Y, Radulovic M, Vietri M, Stenmark H (2021)
Sealing holes in cellular membranes
EMBO J, 40 (7), e106922
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