Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2021 from OUS - Division of Clinical Neuroscience

45 publications found

Andersen MS, Bandres-Ciga S, Reynolds RH, Hardy J, Ryten M, Krohn L, Gan-Or Z, Holtman IR, Pihlstrøm L, International Parkinson's Disease Genomics Consortium (2021)
Heritability Enrichment Implicates Microglia in Parkinson's Disease Pathogenesis
Ann Neurol (in press)
DOI 10.1002/ana.26032, PubMed 33502028

Andreassen S, Lindland EMS, Solheim AM, Beyer MK, Ljøstad U, Mygland Å, Lorentzen ÅR, Reiso H, Harbo HF, Løhaugen GCC, Eikeland R (2021)
Cognitive function, fatigue and Fazekas score in patients with acute neuroborreliosis
Ticks Tick Borne Dis, 12 (3), 101678 (in press)
DOI 10.1016/j.ttbdis.2021.101678, PubMed 33529985

Berge-Seidl V, Pihlstrøm L, Toft M (2021)
Integrative analysis identifies bHLH transcription factors as contributors to Parkinson's disease risk mechanisms
Sci Rep, 11 (1), 3502
DOI 10.1038/s41598-021-83087-2, PubMed 33568722

Bjørke AB, Østby Y, Grahl SG, Larsson PG, Olsen KB, Johansen Nævra MC, Ringstad GA, Bjørnerud A, Gjerstad L, Taubøll E, Heuser K (2021)
Cognition in adult patients with newly diagnosed non-lesional temporal lobe epilepsy
Epilepsy Behav, 116, 107771 (in press)
DOI 10.1016/j.yebeh.2021.107771, PubMed 33545650

Celius EG, Thompson H, Pontaga M, Langdon D, Laroni A, Potra S, Bharadia T, Yeandle D, Shanahan J, van Galen P, Alexandri N, Kesselring J (2021)
Disease Progression in Multiple Sclerosis: A Literature Review Exploring Patient Perspectives
Patient Prefer Adherence, 15, 15-27
DOI 10.2147/PPA.S268829, PubMed 33447018

Choi G, Villanger GD, Drover SSM, Sakhi AK, Thomsen C, Nethery RC, Zeiner P, Knudsen GP, Reichborn-Kjennerud T, Øvergaard KR, Herring AH, Skogan AH, Biele G, Aase H, Engel SM (2021)
Prenatal phthalate exposures and executive function in preschool children
Environ Int, 149, 106403
DOI 10.1016/j.envint.2021.106403, PubMed 33524667

Christensen JO, Nielsen MB, Sannes AC, Gjerstad J (2021)
Leadership Style, Headache, and Neck Pain: The Moderating Role of the Catechol-O-Methyltransferase (COMT) Genotype
J Occup Environ Med, 63 (2), 151-158
DOI 10.1097/JOM.0000000000002103, PubMed 33298758

Christensen JO, Nilsen KB, Hopstock LA, Steingrímsdóttir ÓA, Nielsen CS, Zwart JA, Matre D (2021)
Shift work, low-grade inflammation, and chronic pain: a 7-year prospective study
Int Arch Occup Environ Health (in press)
DOI 10.1007/s00420-020-01626-2, PubMed 33550437

Dahl HM, Andelic N, Løvstad M, Holthe IL, Hestnes M, Diseth TH, Myhre MC (2021)
Epidemiology of traumatic brain injury in children 15 years and younger in South-Eastern Norway in 2015-16. Implications for prevention and follow-up needs
Eur J Paediatr Neurol, 31, 70-77 (in press)
DOI 10.1016/j.ejpn.2021.02.002, PubMed 33647532

Dalton MK, Mjåset C, Manful A, Helgeson MD, Wynn-Jones W, Cooper Z, Koehlmoos TP, Weissman JS (2021)
Strategies for spinal surgery reimbursement: bundling in the working-age population
BMC Health Serv Res, 21 (1), 112
DOI 10.1186/s12913-021-06112-0, PubMed 33530994

Dechsling A, Shic F, Zhang D, Marschik PB, Esposito G, Orm S, Sütterlin S, Kalandadze T, Øien RA, Nordahl-Hansen A (2021)
Virtual reality and naturalistic developmental behavioral interventions for children with autism spectrum disorder
Res Dev Disabil, 111, 103885 (in press)
DOI 10.1016/j.ridd.2021.103885, PubMed 33548742

Forslund MV, Perrin PB, Sigurdardottir S, Howe EI, van Walsem MR, Arango-Lasprilla JC, Lu J, Aza A, Jerstad T, Røe C, Andelic N (2021)
Health-Related Quality of Life Trajectories across 10 Years after Moderate to Severe Traumatic Brain Injury in Norway
J Clin Med, 10 (1)
DOI 10.3390/jcm10010157, PubMed 33466321

Frič R, Langvatn EA, Due-Tønnessen BJ, Eide PK (2021)
The role of pulsatile and static intracranial pressure measurements in the management of children with craniosynostosis-an institutional experience from 49 patients
Acta Neurochir (Wien)
DOI 10.1007/s00701-020-04680-4, PubMed 33389123

Graves WC, Oyesanya TO, Gormley M, Røe C, Andelic N, Seel RT, Lu J (2021)
Pre- and in-hospital mortality for moderate-to-severe traumatic brain injuries: an analysis of the National Trauma Data Bank (2008-2014)
Brain Inj
DOI 10.1080/02699052.2021.1873419, PubMed 33529087

Grimstvedt TN, Miller JU, van Walsem MR, Feragen KJB (2021)
Speech and language difficulties in Huntington's disease: A qualitative study of patients' and professional caregivers' experiences
Int J Lang Commun Disord
DOI 10.1111/1460-6984.12604, PubMed 33577706

Hauger LE, Havnes IA, Jørstad ML, Bjørnebekk A (2021)
Anabolic androgenic steroids, antisocial personality traits, aggression and violence
Drug Alcohol Depend, 221, 108604 (in press)
DOI 10.1016/j.drugalcdep.2021.108604, PubMed 33621808

Hellstrøm T, Andelic N, de Lange AG, Helseth E, Eiklid K, Westlye LT (2021)
Apolipoprotein ɛ4 Status and Brain Structure 12 Months after Mild Traumatic Injury: Brain Age Prediction Using Brain Morphometry and Diffusion Tensor Imaging
J Clin Med, 10 (3)
DOI 10.3390/jcm10030418, PubMed 33499167

Henning O, Nakken KO (2021)
The start of epilepsy care in Norway
Tidsskr Nor Laegeforen, 141 (2)
DOI 10.4045/tidsskr.20.0731, PubMed 33528132

Johannessen Landmark C, Potschka H, Auvin S, Wilmshurst JM, Johannessen SI, Kasteleijn-Nolst Trenité D, Wirrell EC (2021)
The role of new medical treatments for the management of developmental and epileptic encephalopathies: Novel concepts and results
Epilepsia (in press)
DOI 10.1111/epi.16849, PubMed 33638459

Kam JWY, Helfrich RF, Solbakk AK, Endestad T, Larsson PG, Lin JJ, Knight RT (2021)
Top-Down Attentional Modulation in Human Frontal Cortex: Differential Engagement during External and Internal Attention
Cereb Cortex, 31 (2), 873-883
DOI 10.1093/cercor/bhaa262, PubMed 33063100

Khan H, Naseer N, Yazidi A, Eide PK, Hassan HW, Mirtaheri P (2021)
Analysis of Human Gait Using Hybrid EEG-fNIRS-Based BCI System: A Review
Front Hum Neurosci, 14, 613254
DOI 10.3389/fnhum.2020.613254, PubMed 33568979

Kristoffersen ES, Jahr SH, Faiz KW, Storstein AM, Winsvold BS, Sandset EC (2021)
Acute stroke care during the first phase of COVID-19 pandemic in Norway
Acta Neurol Scand
DOI 10.1111/ane.13392, PubMed 33421104

Kristoffersen ES, Winsvold BS, Sandset EC, Storstein AM, Faiz KW (2021)
Experiences, distress and burden among neurologists in Norway during the COVID-19 pandemic
PLoS One, 16 (2), e0246567
DOI 10.1371/journal.pone.0246567, PubMed 33539418

Kuseyri Hübschmann O, Mohr A, Friedman J, Manti F, Horvath G, Cortès-Saladelafont E, Mercimek-Andrews S, Yildiz Y, Pons R, Kulhánek J, Oppebøen M, Koht JA, Podzamczer-Valls I, Domingo-Jimenez R, Ibáñez S, Alcoverro-Fortuny O, Gómez-Alemany T, de Castro P, Alfonsi C, Zafeiriou DI, López-Laso E, Guder P, Santer R, Honzík T, Hoffmann GF et al. (2021)
Brain MR patterns in inherited disorders of monoamine neurotransmitters: An analysis of 70 patients
J Inherit Metab Dis
DOI 10.1002/jimd.12360, PubMed 33443316

Langmyhr M, Henriksen SP, Cappelletti C, van de Berg WDJ, Pihlstrøm L, Toft M (2021)
Allele-specific expression of Parkinson's disease susceptibility genes in human brain
Sci Rep, 11 (1), 504
DOI 10.1038/s41598-020-79990-9, PubMed 33436766

Liebrand M, Solbakk AK, Funderud I, Buades-Rotger M, Knight RT, Krämer UM (2021)
Intact Proactive Motor Inhibition after Unilateral Prefrontal Cortex or Basal Ganglia Lesions
J Cogn Neurosci, 1-18 (in press)
DOI 10.1162/jocn_a_01691, PubMed 33571074

Major DH, Grotle M, Littlewood C, Brox JI, Matre D, Gallet HV, Røe Y (2021)
Adherence to self-managed exercises for patients with persistent subacromial pain: the Ad-Shoulder feasibility study
Pilot Feasibility Stud, 7 (1), 31
DOI 10.1186/s40814-021-00767-6, PubMed 33494821

Nordheim E, Lindahl JP, Carlsen RK, Åsberg A, Birkeland KI, Horneland R, Boye B, Scholz H, Jenssen TG (2021)
Patient selection for islet or solid organ pancreas transplantation: experiences from a multidisciplinary outpatient-clinic approach
Endocr Connect (in press)
DOI 10.1530/EC-20-0519, PubMed 33544090

Remus A, Smith V, Gutke A, Mena JJS, Mørkved S, Wikmar LN, Öberg B, Olsson C, Robinson HS, Stuge B, Wuytack F (2021)
A core outcome set for research and clinical practice in women with pelvic girdle pain: PGP-COS
PLoS One, 16 (2), e0247466
DOI 10.1371/journal.pone.0247466, PubMed 33630941

Rizvi SAM, Helseth E, Aarhus M, Harr ME, Mirzamohammadi J, Rønning P, Mejlænder-Evjensvold M, Linnerud H (2021)
Favorable prognosis with nonsurgical management of type III acute odontoid fractures: a consecutive series of 212 patients
Spine J (in press)
DOI 10.1016/j.spinee.2021.02.003, PubMed 33577924

Roaldsen MB, Lindekleiv H, Eltoft A, Jusufovic M, Søyland MH, Petersson J, Indredavik B, Tveiten A, Putaala J, Christensen H, Kõrv J, Jatužis D, Engelter ST, Marco De Marchis G, Wilsgaard T, Werring DJ, Robinson T, Mathiesen EB, Berge E (2021)
Tenecteplase in wake-up ischemic stroke trial: Protocol for a randomized-controlled trial
Int J Stroke, 1747493020984073 (in press)
DOI 10.1177/1747493020984073, PubMed 33446083

Rødevand L, Bahrami S, Frei O, Lin A, Gani O, Shadrin A, Smeland OB, Connell KSO, Elvsåshagen T, Winterton A, Quintana DS, Hindley GFL, Werner MCF, Djurovic S, Dale AM, Lagerberg TV, Steen NE, Andreassen OA (2021)
Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms
Transl Psychiatry, 11 (1), 3
DOI 10.1038/s41398-020-01142-4, PubMed 33414458

Sandset EC, Goldstein LB (2021)
Treatments-Preventive
Stroke, 52 (3), 1118-1120
DOI 10.1161/STROKEAHA.120.033236, PubMed 33563014

Shrestha D, Shrestha R, Grotle M, Nygaard ØP, Solberg TK (2021)
Validation of the Nepali versions of the Neck Disability Index and the Numerical Rating Scale for Neck Pain
Spine (Phila Pa 1976), 46 (5), E325-E332
DOI 10.1097/BRS.0000000000003810, PubMed 33181772

Song L, Wang X, Ouyang M, Sun L, Chen X, Arima H, Sandset EC, Delcourt C, Wang J, Chen G, Robinson T, Lindley RI, Chalmers J, Anderson CS, INTERACT2 Investigators (2021)
Associations of an Abnormal Physiological Score With Outcomes in Acute Intracerebral Hemorrhage: INTERACT2 Study
Stroke, 52 (2), 722-725
DOI 10.1161/STROKEAHA.120.030435, PubMed 33423518

Sorteberg A, Romundstad L, Sorteberg W (2021)
Timelines and rebleeds in patients admitted into neurosurgical care for aneurysmal subarachnoid haemorrhage
Acta Neurochir (Wien), 163 (3), 771-781
DOI 10.1007/s00701-020-04673-3, PubMed 33409740

Svensson SF, De Arcos J, Darwish OI, Fraser-Green J, Storås TH, Holm S, Vik-Mo EO, Sinkus R, Emblem KE (2021)
Robustness of MR Elastography in the Healthy Brain: Repeatability, Reliability, and Effect of Different Reconstruction Methods
J Magn Reson Imaging
DOI 10.1002/jmri.27475, PubMed 33403750

Tsivgoulis G, Katsanos AH, Mandava P, Köhrmann M, Soinne L, Barreto AD, Sharma VK, Mikulik R, Muir KW, Rothlisberger T, Grotta JC, Levi CR, Molina CA, Saqqur M, Mavridis D, Psaltopoulou T, Vosko MR, Fiebach JB, Sandset EC, Kent TA, Alexandrov AW, Schellinger PD, Alexandrov AV, CLOTBUST-ER Trial Investigators (2021)
Blood pressure excursions in acute ischemic stroke patients treated with intravenous thrombolysis
J Hypertens, 39 (2), 266-272
DOI 10.1097/HJH.0000000000002628, PubMed 32956103

Tunold JA, Geut H, Rozemuller JMA, Henriksen SP, Toft M, van de Berg WDJ, Pihlstrøm L (2021)
APOE and MAPT Are Associated With Dementia in Neuropathologically Confirmed Parkinson's Disease
Front Neurol, 12, 631145
DOI 10.3389/fneur.2021.631145, PubMed 33613437

Vlachos G, Ihle-Hansen H, Bruun Wyller T, Brækhus A, Mangset M, Hamre C, Fure B (2021)
Cognitive and emotional symptoms in patients with first-ever mild stroke: The syndrome of hidden impairments
J Rehabil Med, 53 (1), jrm00135
DOI 10.2340/16501977-2764, PubMed 33145603

Wang X, Moullaali TJ, Ouyang M, Billot L, Sandset EC, Song L, Delcourt C, Hackett ML, Watkins CL, Robinson TG, Yang J, Lavados PM, Brunser A, Olavarría VV, Muñoz-Venturelli P, Arima H, Middleton S, Pontes-Neto OM, Pandian JD, Rogers K, Anderson CS (2021)
Influence of Including Patients with Premorbid Disability in Acute Stroke Trials: The HeadPoST Experience
Cerebrovasc Dis, 50 (1), 78-87
DOI 10.1159/000512608, PubMed 33434907

Welland NL, Hæstad H, Ludt Fossmo H, Giltvedt K, Kristin Ø, Nordstrøm M (2021)
The Role of Nutrition and Physical Activity as Trigger Factors of Paralytic Attacks in Primary Periodic Paralysis
J Neuromuscul Dis (in press)
DOI 10.3233/JND-200604, PubMed 33646174

Werland F, Hirth M, Rukwied R, Ringkamp M, Turnquist B, Jorum E, Namer B, Schmelz M, Obreja O (2021)
Maximum axonal following frequency separates classes of cutaneous unmyelinated nociceptors in the pig
J Physiol, 599 (5), 1595-1610
DOI 10.1113/JP280269, PubMed 33369733

Wesnes K, Myhr KM, Riise T, Kvistad SS, Torkildsen Ø, Wergeland S, Holmøy T, Midgard R, Bru A, Edland A, Eikeland R, Gosal S, Harbo HF, Kleveland G, Sørenes YS, Øksendal N, Bjørnevik K (2021)
Low vitamin D, but not tobacco use or high BMI, is associated with long-term disability progression in multiple sclerosis
Mult Scler Relat Disord, 50, 102801 (in press)
DOI 10.1016/j.msard.2021.102801, PubMed 33636616

Wimmer H, Lundqvist C, Šaltytė Benth J, Stavem K, Andersen GØ, Henriksen J, Drægni T, Sunde K, Nakstad ER (2021)
Health-related quality of life after out-of-hospital cardiac arrest - a five-year follow-up study
Resuscitation (in press)
DOI 10.1016/j.resuscitation.2021.01.036, PubMed 33571604

 
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