Per Steinar Halvorsen
- Consultant; MD, PhD
- +47 23 07 01 52
Publications 2024
The impact of hypovolemia and PEEP on recirculation in venovenous ECMO: an experimental porcine model
Intensive Care Med Exp, 12 (1), 51
DOI 10.1186/s40635-024-00636-5, PubMed 38822111
Publications 2023
Detection of inflow obstruction in left ventricular assist devices by accelerometer: A porcine model study
J Heart Lung Transplant, 42 (8), 1005-1014
DOI 10.1016/j.healun.2023.03.017, PubMed 37023840
Extracorporeal driveline vibrations to detect left ventricular assist device thrombosis - A porcine model study
J Heart Lung Transplant, 43 (1), 111-119
DOI 10.1016/j.healun.2023.08.022, PubMed 37673384
Publications 2022
Detection of inflow obstruction in left ventricular assist devices by accelerometer: An in vitro study
Med Eng Phys, 110, 103917
DOI 10.1016/j.medengphy.2022.103917, PubMed 36564132
Improved Detection Of Thromboembolic Complications In Left Ventricular Assist Device By Novel Accelerometer-Based Analysis
ASAIO J, 68 (9), 1117-1125
DOI 10.1097/MAT.0000000000001654, PubMed 36066353
Automatic Detection of Aortic Valve Events Using Deep Neural Networks on Cardiac Signals From Epicardially Placed Accelerometer
IEEE J Biomed Health Inform, 26 (9), 4450-4461
DOI 10.1109/JBHI.2022.3181148, PubMed 35679388
Left Ventricular Function Changes Induced by Moderate Hypothermia Are Rapidly Reversed After Rewarming-A Clinical Study
Crit Care Med, 50 (1), e52-e60
DOI 10.1097/CCM.0000000000005170, PubMed 34259452
Myocardial electrophysiological and mechanical changes caused by moderate hypothermia-A clinical study
Physiol Rep, 10 (8), e15259
DOI 10.14814/phy2.15259, PubMed 35439365
Publications 2021
Continuous Estimation of Acute Changes in Preload Using Epicardially Attached Accelerometers
IEEE Trans Biomed Eng, 68 (7), 2067-2075
DOI 10.1109/TBME.2020.3020358, PubMed 32866091
Open chest and pericardium facilitate transpulmonary passage of venous air emboli
Acta Anaesthesiol Scand, 65 (5), 648-655
DOI 10.1111/aas.13796, PubMed 33595102
Publications 2020
A New Real Time Clinical Decision Support System Using Machine Learning for Critical Care Units
IEEE Access, 8, 185676-185687
DOI 10.1109/ACCESS.2020.3030031
Left Ventricular Function During Epinephrine Stimulation and Hypothermia: Effects at Spontaneous and Paced Heart Rates in a Porcine Model
Ther Hypothermia Temp Manag, 11 (1), 35-44
DOI 10.1089/ther.2019.0035, PubMed 31916922
Safety and feasibility of dobutamine stress echocardiography in symptomatic high gradient aortic stenosis patients scheduled for transcatheter aortic valve implantation
J Clin Ultrasound, 49 (1), 38-48
DOI 10.1002/jcu.22915, PubMed 32914454
Detection of Thromboembolic Events and Pump Thrombosis in HeartWare HVAD Using Accelerometer in a Porcine Model
ASAIO J, 66 (1), 38-48
DOI 10.1097/MAT.0000000000000954, PubMed 30688692
Automatic detection of valve events by epicardial accelerometer allows estimation of the left ventricular pressure trace and pressure-displacement loop area
Sci Rep, 10 (1), 20088
DOI 10.1038/s41598-020-76637-7, PubMed 33208784
Changes in left ventricular electromechanical relations during targeted hypothermia
Intensive Care Med Exp, 8 (1), 76
DOI 10.1186/s40635-020-00363-7, PubMed 33315166
Publications 2019
Technological and Clinical Challenges in Lead Placement for Cardiac Rhythm Management Devices
Ann Biomed Eng, 48 (1), 26-46
DOI 10.1007/s10439-019-02376-0, PubMed 31576502
Can we ablate liver lesions close to large portal and hepatic veins with MR-guided HIFU? An experimental study in a porcine model
Eur Radiol, 29 (9), 5013-5021
DOI 10.1007/s00330-018-5996-8, PubMed 30737565
Single-centre first experience with transapical transcatheter mitral valve replacement with an apical tether: factors influencing screening outcomes
Interact Cardiovasc Thorac Surg, 28 (5), 695-703
DOI 10.1093/icvts/ivy343, PubMed 30602024
On the Performance of Hierarchical Temporal Memory Predictions of Medical Streams in Real Time
INT SYM MED INFORM, 157-162
Esmolol for cardioprotection during resuscitation with adrenaline in an ischaemic porcine cardiac arrest model
Intensive Care Med Exp, 7 (1), 65
DOI 10.1186/s40635-019-0279-5, PubMed 31802327
Dynamic gravity compensation does not increase detection of myocardial ischemia in combined accelerometer and gyro sensor measurements
Sci Rep, 9 (1), 2671
DOI 10.1038/s41598-018-35630-x, PubMed 30804438
Multi-nodal nano-actuator pacemaker for energy-efficient stimulation of cardiomyocytes
Nano Commun.Netw., 22, 100270
DOI 10.1016/j.nancom.2019.100270
Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model
PLoS One, 14 (6), e0218624
DOI 10.1371/journal.pone.0218624, PubMed 31247004
Monitoring cardiac function by accelerometer - detecting start systole from the acceleration signal makes additional ECG recordings for R-peak detection redundant
Annu Int Conf IEEE Eng Med Biol Soc, 2019, 4922-4925
DOI 10.1109/EMBC.2019.8856417, PubMed 31946964
Monitoring cardiac function by accelerometer - detecting start systole from the acceleration signal makes additional ECG recordings for R-peak detection redundant
IEEE ENG MED BIO, 4922-4925
Publications 2018
Left Ventricle Function During Therapeutic Hypothermia with Beta1-Adrenergic Receptor Blockade
Ther Hypothermia Temp Manag, 8 (3), 156-164
DOI 10.1089/ther.2017.0051, PubMed 29394143
Haemodynamic evaluation and optimisation of brain-dead donors with oesophageal Doppler during organ harvesting: A feasibility study
Eur J Anaesthesiol, 35 (11), 893-895
DOI 10.1097/EJA.0000000000000876, PubMed 30278032
Corrigendum to 'Left ventricular function can be continuously monitored with an epicardially attached accelerometer sensor' [Eur J Cardiothorac Surg 2014;46:313-20]
Eur J Cardiothorac Surg, 54 (5), 968
DOI 10.1093/ejcts/ezy340, PubMed 30295773
Accelerometer Detects Pump Thrombosis and Thromboembolic Events in an In vitro HVAD Circuit
ASAIO J, 64 (5), 601-609
DOI 10.1097/MAT.0000000000000699, PubMed 29088023
Publications 2017
Reduced inflammatory response by transcatheter, as compared to surgical aortic valve replacement
Scand Cardiovasc J, 52 (1), 43-50
DOI 10.1080/14017431.2017.1416157, PubMed 29233022
Detection of intraoperative myocardial dysfunction by accelerometer during aortic valve replacement
Interact Cardiovasc Thorac Surg, 24 (2), 188-195
DOI 10.1093/icvts/ivw326, PubMed 28364479
Urinary Kinetics of Heroin Metabolites in Pigs Shortly After Intake
J Anal Toxicol, 41 (5), 451-454
DOI 10.1093/jat/bkx017, PubMed 28335030
Gravity Compensation Method for Combined Accelerometer and Gyro Sensors Used in Cardiac Motion Measurements
Ann Biomed Eng, 45 (5), 1292-1304
DOI 10.1007/s10439-017-1798-4, PubMed 28116541
Publications 2016
Does therapeutic hypothermia during extracorporeal cardiopulmonary resuscitation preserve cardiac function?
J Transl Med, 14 (1), 345
DOI 10.1186/s12967-016-1099-y, PubMed 27998282
Hypothermia Is Not an Inotropic Drug
Crit Care Med, 44 (12), e1258
DOI 10.1097/CCM.0000000000002048, PubMed 27858830
Long-term outcomes after transcatheter aortic valve implantation: the impact of intraoperative tissue Doppler echocardiography
Interact Cardiovasc Thorac Surg, 23 (3), 403-9
DOI 10.1093/icvts/ivw159, PubMed 27241050
Pharmacokinetics of heroin and its metabolites in vitreous humor and blood in a living pig model
Forensic Toxicol, 34 (2), 277-285
DOI 10.1007/s11419-016-0315-z, PubMed 27660664
BLOOD PRESSURE ESTIMATION USING VIDEO PLETHYSMOGRAPHY
I S BIOMED IMAGING, 461-464
DOI 10.1109/ISBI.2016.7493307
An Implantable Accelerometer-Based Heart-Monitoring Device With Improved Positional Stability
J. Med. Devices, 10 (4), 045002
DOI 10.1115/1.4034574
Publications 2015
Successful ECMO-cardiopulmonary resuscitation with the associated post-arrest cardiac dysfunction as demonstrated by MRI
Intensive Care Med Exp, 3 (1), 61
DOI 10.1186/s40635-015-0061-2, PubMed 26335546
Transcatheter aortic valve implantation and intraoperative left ventricular function: a myocardial tissue Doppler imaging study
J Cardiothorac Vasc Anesth, 29 (1), 115-20
DOI 10.1053/j.jvca.2014.10.016, PubMed 25620143
Intraoperative improvement in left ventricular peak systolic velocity predicts better short-term outcome after transcatheter aortic valve implantation
Interact Cardiovasc Thorac Surg, 22 (1), 5-12
DOI 10.1093/icvts/ivv277, PubMed 26467639
Critical airway obstruction: challenges in airway management and ventilation during therapeutic bronchoscopy
J Bronchology Interv Pulmonol, 22 (1), 41-7
DOI 10.1097/LBR.0000000000000127, PubMed 25590482
In-Body to On-Body Ultrawideband Propagation Model Derived From Measurements in Living Animals
IEEE J Biomed Health Inform, 19 (3), 938-48
DOI 10.1109/JBHI.2015.2417805, PubMed 25861089
Continuous monitoring of cardiac function by 3-dimensional accelerometers in a closed-chest pig model
Interact Cardiovasc Thorac Surg, 21 (5), 573-82
DOI 10.1093/icvts/ivv191, PubMed 26254463
Continuous monitoring of regional function by a miniaturized ultrasound transducer allows early quantification of low-grade myocardial ischemia
J Am Soc Echocardiogr, 28 (4), 486-94
DOI 10.1016/j.echo.2014.12.014, PubMed 25636368
Systolic left ventricular function is preserved during therapeutic hypothermia, also during increases in heart rate with impaired diastolic filling
Intensive Care Med Exp, 3 (1), 41
DOI 10.1186/s40635-015-0041-6, PubMed 26215808
Publications 2014
Thermal fixation of swine liver tissue after magnetic resonance-guided high-intensity focused ultrasound ablation
Ultrasound Med Biol, 40 (7), 1564-77
DOI 10.1016/j.ultrasmedbio.2014.02.007, PubMed 24768489
Assessment of 3D motion increases the applicability of accelerometers for monitoring left ventricular function
Interact Cardiovasc Thorac Surg, 20 (3), 329-37
DOI 10.1093/icvts/ivu404, PubMed 25472979
Advantages of strain echocardiography in assessment of myocardial function in severe sepsis: an experimental study
Crit Care Med, 42 (6), e432-40
DOI 10.1097/CCM.0000000000000310, PubMed 24633187
Left ventricular function can be continuously monitored with an epicardially attached accelerometer sensor
Eur J Cardiothorac Surg, 46 (2), 313-20
DOI 10.1093/ejcts/ezt653, PubMed 24482390
Packaging of a Multifunctional Implantable Heart Monitoring Device
2014 SYMPOSIUM ON DESIGN, TEST, INTEGRATION AND PACKAGING OF MEMS/MOEMS (DTIP), 322-327
Myocardial tissue CO2 tension detects coronary blood flow reduction after coronary artery bypass in real-time†
Br J Anaesth, 114 (3), 414-22
DOI 10.1093/bja/aeu381, PubMed 25392231
Fabrication and assembly of MEMS accelerometer-based heart monitoring device with simplified, one step placement
J Med Eng Technol, 39 (1), 69-74
DOI 10.3109/03091902.2014.981307, PubMed 25429874
MEMS-Based Implantable Heart Monitoring System with Integrated Pacing Function
ELEC COMP C, 139-144
Publications 2013
Effects of therapeutic hypothermia on left ventricular function assessed by ultrasound imaging
J Am Soc Echocardiogr, 26 (11), 1353-63
DOI 10.1016/j.echo.2013.06.021, PubMed 23891124
Publications 2012
Perioperative detection of myocardial ischaemia/reperfusion with a novel tissue CO2 monitoring technology
Eur J Cardiothorac Surg, 42 (1), 157-63
DOI 10.1093/ejcts/ezr278, PubMed 22290904
Simulation model of cardiac three dimensional accelerometer measurements
Med Eng Phys, 34 (7), 990-8
DOI 10.1016/j.medengphy.2012.04.015, PubMed 22633656
Publications 2011
Diffuse reflectance spectroscopy: Systemic and microvascular oxygen saturation is linearly correlated and hypoxia leads to increased spatial heterogeneity of microvascular saturation
Microvasc Res, 81 (3), 245-51
DOI 10.1016/j.mvr.2011.02.004, PubMed 21376735
Integration between a percutaneous implant and the porcine small bowel
J Biomed Mater Res B Appl Biomater, 98 (1), 101-9
DOI 10.1002/jbm.b.31838, PubMed 21563306
Publications 2010
Automated detection of myocardial ischaemia by epicardial miniature ultrasound transducers--a novel tool for patient monitoring during cardiac surgery
Eur J Cardiothorac Surg, 39 (1), 53-9
DOI 10.1016/j.ejcts.2010.03.067, PubMed 20627751
Assessments of skin and tongue microcirculation reveals major changes in porcine sepsis
Clin Physiol Funct Imaging, 31 (2), 151-8
DOI 10.1111/j.1475-097X.2010.00994.x, PubMed 21087397
Publications 2009
Intracoronary shunt prevents ischemia in off-pump coronary artery bypass surgery
Ann Thorac Surg, 87 (1), 54-60
DOI 10.1016/j.athoracsur.2008.08.032, PubMed 19101268
Detecting myocardial ischaemia using miniature ultrasonic transducers--a feasibility study in a porcine model
Eur J Cardiothorac Surg, 37 (1), 119-26
DOI 10.1016/j.ejcts.2009.05.013, PubMed 19581103
Automatic real-time detection of myocardial ischemia by epicardial accelerometer
J Thorac Cardiovasc Surg, 139 (4), 1026-32
DOI 10.1016/j.jtcvs.2009.05.031, PubMed 19717169
Validation of cardiac accelerometer sensor measurements
Physiol Meas, 30 (12), 1429-44
DOI 10.1088/0967-3334/30/12/010, PubMed 19907074
Publications 2008
Epicardial Acceleration Signal Measured Using a Single Chip 3-axis Accelerometer
IFMBE PROC, 20, 221-+
Feasibility of a three-axis epicardial accelerometer in detecting myocardial ischemia in cardiac surgical patients
J Thorac Cardiovasc Surg, 136 (6), 1496-502
DOI 10.1016/j.jtcvs.2008.08.043, PubMed 19114197
Detection of myocardial ischaemia by epicardial accelerometers in the pig
Br J Anaesth, 102 (1), 29-37
DOI 10.1093/bja/aen331, PubMed 19022793
Publications 2007
Microbubbles in the pulmonary artery generated during experimental hepatic radiofrequency ablation is correlated with increased pulmonary arterial pressure
J Vasc Interv Radiol, 18 (3), 437-42
DOI 10.1016/j.jvir.2006.12.010, PubMed 17377191
Continuous cardiac output during off-pump coronary artery bypass surgery: pulse-contour analyses vs pulmonary artery thermodilution
Br J Anaesth, 99 (4), 484-92
DOI 10.1093/bja/aem199, PubMed 17650518
Epicardial ultrasonography: a potential method for intraoperative quality assessment of coronary bypass anastomoses?
Ann Thorac Surg, 84 (3), 801-7
DOI 10.1016/j.athoracsur.2007.04.025, PubMed 17720379
Assembly and packaging of a three-axis micro accelerometer used for detection of heart infarction
Biomed Microdevices, 9 (6), 951-7
DOI 10.1007/s10544-007-9082-2, PubMed 17492383
Publications 2006
Agreement between PiCCO pulse-contour analysis, pulmonal artery thermodilution and transthoracic thermodilution during off-pump coronary artery by-pass surgery
Acta Anaesthesiol Scand, 50 (9), 1050-7
DOI 10.1111/j.1399-6576.2006.01118.x, PubMed 16987335
Publications 2005
Early recognition of regional cardiac ischemia using a 3-axis accelerometer sensor
Physiol Meas, 26 (4), 429-40
DOI 10.1088/0967-3334/26/4/009, PubMed 15886438
Preoperative cerebral ischemic lesions predict physical health status after on-pump coronary artery bypass surgery
J Thorac Cardiovasc Surg, 130 (6), 1691-7
DOI 10.1016/j.jtcvs.2005.08.008, PubMed 16308017
Cerebral microembolization during off-pump coronary artery bypass surgery with the Symmetry aortic connector device
J Thorac Cardiovasc Surg, 130 (6), 1581-5
DOI 10.1016/j.jtcvs.2005.08.015, PubMed 16308002
Publications 2004
Intraoperative and intermediate-term angiographic results of coronary artery bypass surgery with Symmetry proximal anastomotic device
J Thorac Cardiovasc Surg, 128 (5), 718-23
DOI 10.1016/j.jtcvs.2004.07.001, PubMed 15514599
Publications 1990
[Occupational health care, coordination with primary health care]
Tidsskr Nor Laegeforen, 110 (8), 991-2
PubMed 2321236