Publications 2022

Bohlin J, Page CM, Lee Y, Pettersson JH, Jugessur A, Magnus P, Håberg SE (2022)
Age and sex effects on DNA methylation sites linked to genes implicated in severe COVID-19 and SARS-CoV-2 host cell entry
PLoS One, 17 (6), e0269105
DOI 10.1371/journal.pone.0269105, PubMed 35679253

Carlsen EØ, Lee Y, Magnus P, Jugessur A, Page CM, Nustad HE, Håberg SE, Lie RT, Magnus MC (2022)
An examination of mediation by DNA methylation on birthweight differences induced by assisted reproductive technologies
Clin Epigenetics, 14 (1), 151
DOI 10.1186/s13148-022-01381-w, PubMed 36443807

Choi HJ, LeBlanc M, Moger TA, Valberg M, Aamodt G, Page CM, Tell GS, Næss Ø (2022)
Stroke survival and the impact of geographic proximity to family members: A population-based cohort study
Soc Sci Med, 309, 115252
DOI 10.1016/j.socscimed.2022.115252, PubMed 35988529

Denault WRP, Bohlin J, Page CM, Burgess S, Jugessur A (2022)
Cross-fitted instrument: A blueprint for one-sample Mendelian randomization
PLoS Comput Biol, 18 (8), e1010268
DOI 10.1371/journal.pcbi.1010268, PubMed 36037248

Hernáez Á, Wootton RE, Page CM, Skåra KH, Fraser A, Rogne T, Magnus P, Njølstad PR, Andreassen OA, Burgess S, Lawlor DA, Magnus MC (2022)
Smoking and infertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study
Fertil Steril, 118 (1), 180-190
DOI 10.1016/j.fertnstert.2022.04.001, PubMed 35562204

Håberg SE, Page CM, Lee Y, Nustad HE, Magnus MC, Haftorn KL, Carlsen EØ, Denault WRP, Bohlin J, Jugessur A, Magnus P, Gjessing HK, Lyle R (2022)
DNA methylation in newborns conceived by assisted reproductive technology
Nat Commun, 13 (1), 1896
DOI 10.1038/s41467-022-29540-w, PubMed 35393427

Lee Y, Bohlin J, Page CM, Nustad HE, Harris JR, Magnus P, Jugessur A, Magnus MC, Håberg SE, Hanevik HI (2022)
Associations between epigenetic age acceleration and infertility
Hum Reprod, 37 (9), 2063-2074
DOI 10.1093/humrep/deac147, PubMed 35771672

Page CM, Nøst TH, Djordjilović V, Thoresen M, Frigessi A, Sandanger TM, Veierød MB (2022)
Pre-diagnostic DNA methylation in blood leucocytes in cutaneous melanoma; a nested case-control study within the Norwegian Women and Cancer cohort
Sci Rep, 12 (1), 14200
DOI 10.1038/s41598-022-18585-y, PubMed 35987900

Sammallahti S, Koopman-Verhoeff ME, Binter AC, Mulder RH, Cabré-Riera A, Kvist T, Malmberg ALK, Pesce G, Plancoulaine S, Heiss JA, Rifas-Shiman SL, Röder SW, Starling AP, Wilson R, Guerlich K, Haftorn KL, Page CM, Luik AI, Tiemeier H, Felix JF, Raikkonen K, Lahti J, Relton CL, Sharp GC, Waldenberger M et al. (2022)
Longitudinal associations of DNA methylation and sleep in children: a meta-analysis
Clin Epigenetics, 14 (1), 83
DOI 10.1186/s13148-022-01298-4, PubMed 35790973

Solomon O, Huen K, Yousefi P, Küpers LK, González JR, Suderman M, Reese SE, Page CM, Gruzieva O, Rzehak P, Gao L, Bakulski KM, Novoloaca A, Allard C, Pappa I, Llambrich M, Vives M, Jima DD, Kvist T, Baccarelli A, White C, Rezwan FI, Sharp GC, Tindula G, Bergström A et al. (2022)
Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation
Mutat Res Rev Mutat Res, 789, 108415
DOI 10.1016/j.mrrev.2022.108415, PubMed 35690418

Publications 2021

Caramaschi D, Jungius J, Page CM, Novakovic B, Saffery R, Halliday J, Lewis S, Magnus MC, London SJ, Håberg SE, Relton CL, Lawlor DA, Elliott HR (2021)
Association of medically assisted reproduction with offspring cord blood DNA methylation across cohorts
Hum Reprod, 36 (8), 2403-2413
DOI 10.1093/humrep/deab137, PubMed 34136910

Haftorn KL, Lee Y, Denault WRP, Page CM, Nustad HE, Lyle R, Gjessing HK, Malmberg A, Magnus MC, Næss Ø, Czamara D, Räikkönen K, Lahti J, Magnus P, Håberg SE, Jugessur A, Bohlin J (2021)
An EPIC predictor of gestational age and its application to newborns conceived by assisted reproductive technologies
Clin Epigenetics, 13 (1), 82
DOI 10.1186/s13148-021-01055-z, PubMed 33875015

Hernáez Á, Rogne T, Skåra KH, Håberg SE, Page CM, Fraser A, Burgess S, Lawlor DA, Magnus MC (2021)
Body mass index and subfertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study
Hum Reprod, 36 (12), 3141-3151
DOI 10.1093/humrep/deab224, PubMed 34668019

Mygland L, Brinch SA, Strand MF, Olsen PA, Aizenshtadt A, Lund K, Solberg NT, Lycke M, Thorvaldsen TE, Espada S, Misaghian D, Page CM, Agafonov O, Nygård S, Chi NW, Lin E, Tan J, Yu Y, Costa M, Krauss S, Waaler J (2021)
Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
iScience, 24 (7), 102807
DOI 10.1016/j.isci.2021.102807, PubMed 34337362

Sammallahti S, Cortes Hidalgo AP, Tuominen S, Malmberg A, Mulder RH, Brunst KJ, Alemany S, McBride NS, Yousefi P, Heiss JA, McRae N, Page CM, Jin J, Pesce G, Caramaschi D, Rifas-Shiman SL, Koen N, Adams CD, Magnus MC, Baïz N, Ratanatharathorn A, Czamara D, Håberg SE, Colicino E, Baccarelli AA et al. (2021)
Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation
Mol Psychiatry, 26 (6), 1832-1845
DOI 10.1038/s41380-020-00976-0, PubMed 33414500

Sharp GC, Alfano R, Ghantous A, Urquiza J, Rifas-Shiman SL, Page CM, Jin J, Fernández-Barrés S, Santorelli G, Tindula G, 36 other members of the Pregnancy and Childhood Epigenetics (PACE) consortium (2021)
Paternal body mass index and offspring DNA methylation: findings from the PACE consortium
Int J Epidemiol, 50 (4), 1297-1315
DOI 10.1093/ije/dyaa267, PubMed 33517419

Publications 2020

Lee Y, Haftorn KL, Denault WRP, Nustad HE, Page CM, Lyle R, Lee-Ødegård S, Moen GH, Prasad RB, Groop LC, Sletner L, Sommer C, Magnus MC, Gjessing HK, Harris JR, Magnus P, Håberg SE, Jugessur A, Bohlin J (2020)
Blood-based epigenetic estimators of chronological age in human adults using DNA methylation data from the Illumina MethylationEPIC array
BMC Genomics, 21 (1), 747
DOI 10.1186/s12864-020-07168-8, PubMed 33109080

Merid SK, Novoloaca A, Sharp GC, Küpers LK, Kho AT, Roy R, Gao L, Annesi-Maesano I, Jain P, Plusquin M, Kogevinas M, Allard C, Vehmeijer FO, Kazmi N, Salas LA, Rezwan FI, Zhang H, Sebert S, Czamara D, Rifas-Shiman SL, Melton PE, Lawlor DA, Pershagen G, Breton CV, Huen K et al. (2020)
Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age
Genome Med, 12 (1), 25
DOI 10.1186/s13073-020-0716-9, PubMed 32114984

Page CM, Djordjilović V, Nøst TH, Ghiasvand R, Sandanger TM, Frigessi A, Thoresen M, Veierød MB (2020)
Lifetime Ultraviolet Radiation Exposure and DNA Methylation in Blood Leukocytes: The Norwegian Women and Cancer Study
Sci Rep, 10 (1), 4521
DOI 10.1038/s41598-020-61430-3, PubMed 32161338

Publications 2019

Bucher-Johannessen C, Page CM, Haugen TB, Wojewodzic MW, Fosså SD, Grotmol T, Haugnes HS, Rounge TB (2019)
Cisplatin treatment of testicular cancer patients introduces long-term changes in the epigenome
Clin Epigenetics, 11 (1), 179
DOI 10.1186/s13148-019-0764-4, PubMed 31796056

Czamara D, Eraslan G, Page CM, Lahti J, Lahti-Pulkkinen M, Hämäläinen E, Kajantie E, Laivuori H, Villa PM, Reynolds RM, Nystad W, Håberg SE, London SJ, O'Donnell KJ, Garg E, Meaney MJ, Entringer S, Wadhwa PD, Buss C, Jones MJ, Lin DTS, MacIsaac JL, Kobor MS, Koen N, Zar HJ et al. (2019)
Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns
Nat Commun, 10 (1), 2548
DOI 10.1038/s41467-019-10461-0, PubMed 31186427

Djordjilović V, Page CM, Gran JM, Nøst TH, Sandanger TM, Veierød MB, Thoresen M (2019)
Global test for high-dimensional mediation: Testing groups of potential mediators
Stat Med, 38 (18), 3346-3360
DOI 10.1002/sim.8199, PubMed 31074092

Kazmi N, Sharp GC, Reese SE, Vehmeijer FO, Lahti J, Page CM, Zhang W, Rifas-Shiman SL, Rezwan FI, Simpkin AJ, Burrows K, Richardson TG, Santos Ferreira DL, Fraser A, Harmon QE, Zhao S, Jaddoe VWV, Czamara D, Binder EB, Magnus MC, Håberg SE, Nystad W, Nohr EA, Starling AP, Kechris KJ et al. (2019)
Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns
Hypertension, 74 (2), 375-383
DOI 10.1161/HYPERTENSIONAHA.119.12634, PubMed 31230546

Küpers LK, Monnereau C, Sharp GC, Yousefi P, Salas LA, Ghantous A, Page CM, Reese SE, Wilcox AJ, Czamara D, Starling AP, Novoloaca A, Lent S, Roy R, Hoyo C, Breton CV, Allard C, Just AC, Bakulski KM, Holloway JW, Everson TM, Xu CJ, Huang RC, van der Plaat DA, Wielscher M et al. (2019)
Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight
Nat Commun, 10 (1), 1893
DOI 10.1038/s41467-019-09671-3, PubMed 31015461

Wikenius E, Myhre AM, Page CM, Moe V, Smith L, Heiervang ER, Undlien DE, LeBlanc M (2019)
Prenatal maternal depressive symptoms and infant DNA methylation: a longitudinal epigenome-wide study
Nord J Psychiatry, 73 (4-5), 257-263
DOI 10.1080/08039488.2019.1613446, PubMed 31070508

Publications 2018

Felix JF, Joubert BR, Baccarelli AA, Sharp GC, Almqvist C, Annesi-Maesano I, Arshad H, Baïz N, Bakermans-Kranenburg MJ, Bakulski KM, Binder EB, Bouchard L, Breton CV, Brunekreef B, Brunst KJ, Burchard EG, Bustamante M, Chatzi L, Cheng Munthe-Kaas M, Corpeleijn E, Czamara D, Dabelea D, Davey Smith G, De Boever P, Duijts L et al. (2018)
Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium
Int J Epidemiol, 47 (1), 22-23u
DOI 10.1093/ije/dyx190, PubMed 29025028

Kvaløy K, Page CM, Holmen TL (2018)
Epigenome-wide methylation differences in a group of lean and obese women - A HUNT Study
Sci Rep, 8 (1), 16330
DOI 10.1038/s41598-018-34003-8, PubMed 30397228

LeBlanc M, Nustad HE, Zucknick M, Page CM (2018)
Quality control for Illumina 450K methylation data in the absence of iDat files using correlation structure in pedigrees and repeated measures
BMC Genet, 19 (Suppl 1), 66
DOI 10.1186/s12863-018-0636-5, PubMed 30255766

Magnus MC, Karlstad Ø, Parr CL, Page CM, Nafstad P, Magnus P, London SJ, Wilcox AJ, Nystad W, Håberg SE (2018)
Maternal history of miscarriages and measures of fertility in relation to childhood asthma
Thorax, 74 (2), 106-113
DOI 10.1136/thoraxjnl-2018-211886, PubMed 30514789

Magnus MC, Miliku K, Bauer A, Engel SM, Felix JF, Jaddoe VWV, Lawlor DA, London SJ, Magnus P, McGinnis R, Nystad W, Page CM, Rivadeneira F, Stene LC, Tapia G, Williams N, Bonilla C, Fraser A (2018)
Vitamin D and risk of pregnancy related hypertensive disorders: mendelian randomisation study
BMJ, 361, k2167
DOI 10.1136/bmj.k2167, PubMed 29925546

Magnus MC, Wright RJ, Røysamb E, Parr CL, Karlstad Ø, Page CM, Nafstad P, Håberg SE, London SJ, Nystad W (2018)
Association of Maternal Psychosocial Stress With Increased Risk of Asthma Development in Offspring
Am J Epidemiol, 187 (6), 1199-1209
DOI 10.1093/aje/kwx366, PubMed 29244063

Nustad HE, Almeida M, Canty AJ, LeBlanc M, Page CM, Melton PE (2018)
Epigenetics, heritability and longitudinal analysis
BMC Genet, 19 (Suppl 1), 77
DOI 10.1186/s12863-018-0648-1, PubMed 30255778

Nustad HE, Page CM, Reiner AH, Zucknick M, LeBlanc M (2018)
A Bayesian mixed modeling approach for estimating heritability
BMC Proc, 12 (Suppl 9), 31
DOI 10.1186/s12919-018-0131-z, PubMed 30275883

Page CM, Vos L, Rounge TB, Harbo HF, Andreassen BK (2018)
Assessing genome-wide significance for the detection of differentially methylated regions
Stat Appl Genet Mol Biol, 17 (5)
DOI 10.1515/sagmb-2017-0050, PubMed 30231014

Parr CL, Magnus MC, Karlstad Ø, Holvik K, Lund-Blix NA, Haugen M, Page CM, Nafstad P, Ueland PM, London SJ, Håberg SE, Nystad W (2018)
Vitamin A and D intake in pregnancy, infant supplementation, and asthma development: the Norwegian Mother and Child Cohort
Am J Clin Nutr, 107 (5), 789-798
DOI 10.1093/ajcn/nqy016, PubMed 29722838

Reese SE, Xu CJ, den Dekker HT, Lee MK, Sikdar S, Ruiz-Arenas C, Merid SK, Rezwan FI, Page CM, Ullemar V, Melton PE, Oh SS, Yang IV, Burrows K, Söderhäll C, Jima DD, Gao L, Arathimos R, Küpers LK, Wielscher M, Rzehak P, Lahti J, Laprise C, Madore AM, Ward J et al. (2018)
Epigenome-wide meta-analysis of DNA methylation and childhood asthma
J Allergy Clin Immunol, 143 (6), 2062-2074
DOI 10.1016/j.jaci.2018.11.043, PubMed 30579849

Størdal K, McArdle HJ, Hayes H, Tapia G, Viken MK, Lund-Blix NA, Haugen M, Joner G, Skrivarhaug T, Mårild K, Njølstad PR, Eggesbø M, Mandal S, Page CM, London SJ, Lie BA, Stene LC (2018)
Prenatal iron exposure and childhood type 1 diabetes
Sci Rep, 8 (1), 9067
DOI 10.1038/s41598-018-27391-4, PubMed 29899542

Veierød MB, Page CM, Aaserud S, Bassarova A, Jacobsen KD, Helsing P, Robsahm TE (2018)
Melanoma staging: Varying precision and terminal digit clustering in Breslow thickness data is evident in a population-based study
J Am Acad Dermatol, 79 (1), 118-125.e1
DOI 10.1016/j.jaad.2018.03.023, PubMed 29580861

Publications 2017

Brix MK, Westman E, Simmons A, Ringstad GA, Eide PK, Wagner-Larsen K, Page CM, Vitelli V, Beyer MK (2017)
The Evans' Index revisited: New cut-off levels for use in radiological assessment of ventricular enlargement in the elderly
Eur J Radiol, 95, 28-32
DOI 10.1016/j.ejrad.2017.07.013, PubMed 28987681

Sharp GC, Arathimos R, Reese SE, Page CM, Felix J, Küpers LK, Rifas-Shiman SL, Liu C, Cohorts for Heart and Aging Research in Genomic Epidemiology plus (CHARGE +) methylation alcohol working group, Burrows K, Zhao S, Magnus MC, Duijts L, Corpeleijn E, DeMeo DL, Litonjua A, Baccarelli A, Hivert MF, Oken E, Snieder H, Jaddoe V, Nystad W, London SJ, Relton CL, Zuccolo L (2017)
Maternal alcohol consumption and offspring DNA methylation: findings from six general population-based birth cohorts
Epigenomics, 10 (1), 27-42
DOI 10.2217/epi-2017-0095, PubMed 29172695

Sharp GC, Salas LA, Monnereau C, Allard C, Yousefi P, Everson TM, Bohlin J, Xu Z, Huang RC, Reese SE, Xu CJ, Baïz N, Hoyo C, Agha G, Roy R, Holloway JW, Ghantous A, Merid SK, Bakulski KM, Küpers LK, Zhang H, Richmond RC, Page CM, Duijts L, Lie RT et al. (2017)
Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium
Hum Mol Genet, 26 (20), 4067-4085
DOI 10.1093/hmg/ddx290, PubMed 29016858

Valeri L, Reese SL, Zhao S, Page CM, Nystad W, Coull BA, London SJ (2017)
Misclassified exposure in epigenetic mediation analyses. Does DNA methylation mediate effects of smoking on birthweight?
Epigenomics, 9 (3), 253-265
DOI 10.2217/epi-2016-0145, PubMed 28234025

Winsvold BS, Palta P, Eising E, Page CM, International Headache Genetics Consortium, van den Maagdenberg AM, Palotie A, Zwart JA (2017)
Epigenetic DNA methylation changes associated with headache chronification: A retrospective case-control study
Cephalalgia, 38 (2), 312-322
DOI 10.1177/0333102417690111, PubMed 28103696

Publications 2016

Berge T, Leikfoss IS, Brorson IS, Bos SD, Page CM, Gustavsen MW, Bjølgerud A, Holmøy T, Celius EG, Damoiseaux J, Smolders J, Harbo HF, Spurkland A (2016)
The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells
Genes Immun, 17 (2), 118-27
DOI 10.1038/gene.2015.61, PubMed 26765264

Bohlin J, Håberg SE, Magnus P, Reese SE, Gjessing HK, Magnus MC, Parr CL, Page CM, London SJ, Nystad W (2016)
Prediction of gestational age based on genome-wide differentially methylated regions
Genome Biol, 17 (1), 207
DOI 10.1186/s13059-016-1063-4, PubMed 27717397

Gervin K, Page CM, Aass HC, Jansen MA, Fjeldstad HE, Andreassen BK, Duijts L, van Meurs JB, van Zelm MC, Jaddoe VW, Nordeng H, Knudsen GP, Magnus P, Nystad W, Staff AC, Felix JF, Lyle R (2016)
Cell type specific DNA methylation in cord blood: A 450K-reference data set and cell count-based validation of estimated cell type composition
Epigenetics, 11 (9), 690-698
DOI 10.1080/15592294.2016.1214782, PubMed 27494297

Gruzieva O, Xu CJ, Breton CV, Annesi-Maesano I, Antó JM, Auffray C, Ballereau S, Bellander T, Bousquet J, Bustamante M, Charles MA, de Kluizenaar Y, den Dekker HT, Duijts L, Felix JF, Gehring U, Guxens M, Jaddoe VV, Jankipersadsing SA, Merid SK, Kere J, Kumar A, Lemonnier N, Lepeule J, Nystad W et al. (2016)
Epigenome-Wide Meta-Analysis of Methylation in Children Related to Prenatal NO2 Air Pollution Exposure
Environ Health Perspect, 125 (1), 104-110
DOI 10.1289/EHP36, PubMed 27448387

Rounge TB, Page CM, Lepistö M, Ellonen P, Andreassen BK, Weiderpass E (2016)
Genome-wide DNA methylation in saliva and body size of adolescent girls
Epigenomics, 8 (11), 1495-1505
DOI 10.2217/epi-2016-0045, PubMed 27762626

Suderman M, Stene LC, Bohlin J, Page CM, Holvik K, Parr CL, Magnus MC, Håberg SE, Joubert BR, Wu MC, London SJ, Relton C, Nystad W (2016)
25-Hydroxyvitamin D in pregnancy and genome wide cord blood DNA methylation in two pregnancy cohorts (MoBa and ALSPAC)
J Steroid Biochem Mol Biol, 159, 102-9
DOI 10.1016/j.jsbmb.2016.03.005, PubMed 26953979

Wikenius E, Moe V, Kjellevold M, Smith L, Lyle R, Waagbø R, Page CM, Myhre AM (2016)
The Association between Hair Cortisol and Self-Reported Symptoms of Depression in Pregnant Women
PLoS One, 11 (9), e0161804
DOI 10.1371/journal.pone.0161804, PubMed 27584584

Publications 2015

Bos SD, Page CM, Andreassen BK, Elboudwarej E, Gustavsen MW, Briggs F, Quach H, Leikfoss IS, Bjølgerud A, Berge T, Harbo HF, Barcellos LF (2015)
Genome-wide DNA methylation profiles indicate CD8+ T cell hypermethylation in multiple sclerosis
PLoS One, 10 (3), e0117403
DOI 10.1371/journal.pone.0117403, PubMed 25734800

Page CM, Baranzini SE, Mevik BH, Bos SD, Harbo HF, Andreassen BK (2015)
Assessing the Power of Exome Chips
PLoS One, 10 (10), e0139642
DOI 10.1371/journal.pone.0139642, PubMed 26437075

Publications 2014

Gustavsen MW, Page CM, Moen SM, Bjølgerud A, Berg-Hansen P, Nygaard GO, Sandvik L, Lie BA, Celius EG, Harbo HF (2014)
Environmental exposures and the risk of multiple sclerosis investigated in a Norwegian case-control study
BMC Neurol, 14, 196
DOI 10.1186/s12883-014-0196-x, PubMed 25274070