
Christian M. Page
- Postdoctoral Fellow (Statistician); PhD
Publications 2022
Age and sex effects on DNA methylation sites linked to genes implicated in severe COVID-19 and SARS-CoV-2 host cell entry
PLoS One, 17 (6), e0269105
DOI 10.1371/journal.pone.0269105, PubMed 35679253
An examination of mediation by DNA methylation on birthweight differences induced by assisted reproductive technologies
Clin Epigenetics, 14 (1), 151
DOI 10.1186/s13148-022-01381-w, PubMed 36443807
Stroke survival and the impact of geographic proximity to family members: A population-based cohort study
Soc Sci Med, 309, 115252
DOI 10.1016/j.socscimed.2022.115252, PubMed 35988529
Cross-fitted instrument: A blueprint for one-sample Mendelian randomization
PLoS Comput Biol, 18 (8), e1010268
DOI 10.1371/journal.pcbi.1010268, PubMed 36037248
Smoking and infertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study
Fertil Steril, 118 (1), 180-190
DOI 10.1016/j.fertnstert.2022.04.001, PubMed 35562204
DNA methylation in newborns conceived by assisted reproductive technology
Nat Commun, 13 (1), 1896
DOI 10.1038/s41467-022-29540-w, PubMed 35393427
Associations between epigenetic age acceleration and infertility
Hum Reprod, 37 (9), 2063-2074
DOI 10.1093/humrep/deac147, PubMed 35771672
Pre-diagnostic DNA methylation in blood leucocytes in cutaneous melanoma; a nested case-control study within the Norwegian Women and Cancer cohort
Sci Rep, 12 (1), 14200
DOI 10.1038/s41598-022-18585-y, PubMed 35987900
Longitudinal associations of DNA methylation and sleep in children: a meta-analysis
Clin Epigenetics, 14 (1), 83
DOI 10.1186/s13148-022-01298-4, PubMed 35790973
Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation
Mutat Res Rev Mutat Res, 789, 108415
DOI 10.1016/j.mrrev.2022.108415, PubMed 35690418
Publications 2021
Association of medically assisted reproduction with offspring cord blood DNA methylation across cohorts
Hum Reprod, 36 (8), 2403-2413
DOI 10.1093/humrep/deab137, PubMed 34136910
An EPIC predictor of gestational age and its application to newborns conceived by assisted reproductive technologies
Clin Epigenetics, 13 (1), 82
DOI 10.1186/s13148-021-01055-z, PubMed 33875015
Body mass index and subfertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study
Hum Reprod, 36 (12), 3141-3151
DOI 10.1093/humrep/deab224, PubMed 34668019
Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
iScience, 24 (7), 102807
DOI 10.1016/j.isci.2021.102807, PubMed 34337362
Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation
Mol Psychiatry, 26 (6), 1832-1845
DOI 10.1038/s41380-020-00976-0, PubMed 33414500
Paternal body mass index and offspring DNA methylation: findings from the PACE consortium
Int J Epidemiol, 50 (4), 1297-1315
DOI 10.1093/ije/dyaa267, PubMed 33517419
Publications 2020
Blood-based epigenetic estimators of chronological age in human adults using DNA methylation data from the Illumina MethylationEPIC array
BMC Genomics, 21 (1), 747
DOI 10.1186/s12864-020-07168-8, PubMed 33109080
Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age
Genome Med, 12 (1), 25
DOI 10.1186/s13073-020-0716-9, PubMed 32114984
Lifetime Ultraviolet Radiation Exposure and DNA Methylation in Blood Leukocytes: The Norwegian Women and Cancer Study
Sci Rep, 10 (1), 4521
DOI 10.1038/s41598-020-61430-3, PubMed 32161338
Publications 2019
Cisplatin treatment of testicular cancer patients introduces long-term changes in the epigenome
Clin Epigenetics, 11 (1), 179
DOI 10.1186/s13148-019-0764-4, PubMed 31796056
Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns
Nat Commun, 10 (1), 2548
DOI 10.1038/s41467-019-10461-0, PubMed 31186427
Global test for high-dimensional mediation: Testing groups of potential mediators
Stat Med, 38 (18), 3346-3360
DOI 10.1002/sim.8199, PubMed 31074092
Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns
Hypertension, 74 (2), 375-383
DOI 10.1161/HYPERTENSIONAHA.119.12634, PubMed 31230546
Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight
Nat Commun, 10 (1), 1893
DOI 10.1038/s41467-019-09671-3, PubMed 31015461
Prenatal maternal depressive symptoms and infant DNA methylation: a longitudinal epigenome-wide study
Nord J Psychiatry, 73 (4-5), 257-263
DOI 10.1080/08039488.2019.1613446, PubMed 31070508
Publications 2018
Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium
Int J Epidemiol, 47 (1), 22-23u
DOI 10.1093/ije/dyx190, PubMed 29025028
Epigenome-wide methylation differences in a group of lean and obese women - A HUNT Study
Sci Rep, 8 (1), 16330
DOI 10.1038/s41598-018-34003-8, PubMed 30397228
Quality control for Illumina 450K methylation data in the absence of iDat files using correlation structure in pedigrees and repeated measures
BMC Genet, 19 (Suppl 1), 66
DOI 10.1186/s12863-018-0636-5, PubMed 30255766
Maternal history of miscarriages and measures of fertility in relation to childhood asthma
Thorax, 74 (2), 106-113
DOI 10.1136/thoraxjnl-2018-211886, PubMed 30514789
Vitamin D and risk of pregnancy related hypertensive disorders: mendelian randomisation study
BMJ, 361, k2167
DOI 10.1136/bmj.k2167, PubMed 29925546
Association of Maternal Psychosocial Stress With Increased Risk of Asthma Development in Offspring
Am J Epidemiol, 187 (6), 1199-1209
DOI 10.1093/aje/kwx366, PubMed 29244063
Epigenetics, heritability and longitudinal analysis
BMC Genet, 19 (Suppl 1), 77
DOI 10.1186/s12863-018-0648-1, PubMed 30255778
A Bayesian mixed modeling approach for estimating heritability
BMC Proc, 12 (Suppl 9), 31
DOI 10.1186/s12919-018-0131-z, PubMed 30275883
Assessing genome-wide significance for the detection of differentially methylated regions
Stat Appl Genet Mol Biol, 17 (5)
DOI 10.1515/sagmb-2017-0050, PubMed 30231014
Vitamin A and D intake in pregnancy, infant supplementation, and asthma development: the Norwegian Mother and Child Cohort
Am J Clin Nutr, 107 (5), 789-798
DOI 10.1093/ajcn/nqy016, PubMed 29722838
Epigenome-wide meta-analysis of DNA methylation and childhood asthma
J Allergy Clin Immunol, 143 (6), 2062-2074
DOI 10.1016/j.jaci.2018.11.043, PubMed 30579849
Prenatal iron exposure and childhood type 1 diabetes
Sci Rep, 8 (1), 9067
DOI 10.1038/s41598-018-27391-4, PubMed 29899542
Melanoma staging: Varying precision and terminal digit clustering in Breslow thickness data is evident in a population-based study
J Am Acad Dermatol, 79 (1), 118-125.e1
DOI 10.1016/j.jaad.2018.03.023, PubMed 29580861
Publications 2017
The Evans' Index revisited: New cut-off levels for use in radiological assessment of ventricular enlargement in the elderly
Eur J Radiol, 95, 28-32
DOI 10.1016/j.ejrad.2017.07.013, PubMed 28987681
Maternal alcohol consumption and offspring DNA methylation: findings from six general population-based birth cohorts
Epigenomics, 10 (1), 27-42
DOI 10.2217/epi-2017-0095, PubMed 29172695
Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium
Hum Mol Genet, 26 (20), 4067-4085
DOI 10.1093/hmg/ddx290, PubMed 29016858
Misclassified exposure in epigenetic mediation analyses. Does DNA methylation mediate effects of smoking on birthweight?
Epigenomics, 9 (3), 253-265
DOI 10.2217/epi-2016-0145, PubMed 28234025
Epigenetic DNA methylation changes associated with headache chronification: A retrospective case-control study
Cephalalgia, 38 (2), 312-322
DOI 10.1177/0333102417690111, PubMed 28103696
Publications 2016
The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells
Genes Immun, 17 (2), 118-27
DOI 10.1038/gene.2015.61, PubMed 26765264
Prediction of gestational age based on genome-wide differentially methylated regions
Genome Biol, 17 (1), 207
DOI 10.1186/s13059-016-1063-4, PubMed 27717397
Cell type specific DNA methylation in cord blood: A 450K-reference data set and cell count-based validation of estimated cell type composition
Epigenetics, 11 (9), 690-698
DOI 10.1080/15592294.2016.1214782, PubMed 27494297
Epigenome-Wide Meta-Analysis of Methylation in Children Related to Prenatal NO2 Air Pollution Exposure
Environ Health Perspect, 125 (1), 104-110
DOI 10.1289/EHP36, PubMed 27448387
Genome-wide DNA methylation in saliva and body size of adolescent girls
Epigenomics, 8 (11), 1495-1505
DOI 10.2217/epi-2016-0045, PubMed 27762626
25-Hydroxyvitamin D in pregnancy and genome wide cord blood DNA methylation in two pregnancy cohorts (MoBa and ALSPAC)
J Steroid Biochem Mol Biol, 159, 102-9
DOI 10.1016/j.jsbmb.2016.03.005, PubMed 26953979
The Association between Hair Cortisol and Self-Reported Symptoms of Depression in Pregnant Women
PLoS One, 11 (9), e0161804
DOI 10.1371/journal.pone.0161804, PubMed 27584584
Publications 2015
Genome-wide DNA methylation profiles indicate CD8+ T cell hypermethylation in multiple sclerosis
PLoS One, 10 (3), e0117403
DOI 10.1371/journal.pone.0117403, PubMed 25734800
Assessing the Power of Exome Chips
PLoS One, 10 (10), e0139642
DOI 10.1371/journal.pone.0139642, PubMed 26437075
Publications 2014
Environmental exposures and the risk of multiple sclerosis investigated in a Norwegian case-control study
BMC Neurol, 14, 196
DOI 10.1186/s12883-014-0196-x, PubMed 25274070