Arnoldo Frigessi

  • Researcher
  • +47 22 85 10 04 / 957 35 574

Arnoldo Frigessi is department head at the Oslo University Hospital and professor of statistics at the University of Oslo. He is director of the Oslo Center for Biostatistics and Epidemiology. He leads the centre for research based innovation BigInsight (, a consortium of partners from academia and the public and private sectors. From 2023, he will be the director of the centre of excellence Integreat- The Norwegian centre for knowledge-driven machine learning, funded by the Research Council of Norway.

Frigessi develops new methods in statistics, machine learning and stochastic models to study principles, dynamics and patterns of complex dependence. Currently, he has research collaborations in genomics, personalised medicine, infectious disease modeling including Covid-19, digital twins and preference learning. Frigessi is elected member of the Norwegian Academy of Sciences and Letters and knighted Cavaliere Ordine al Merito della Repubblica Italiana.

CV - Arnoldo Frigessi

Personal UiO website

Google scholar


Publications 2024

Chan LYH, Rø G, Midtbø JE, Di Ruscio F, Watle SSV, Juvet LK, Littmann J, Aavitsland P, Nygård KM, Berg AS, Bukholm G, Kristoffersen AB, Engø-Monsen K, Engebretsen S, Swanson D, Palomares AD, Lindstrøm JC, Frigessi A, de Blasio BF (2024)
Modeling geographic vaccination strategies for COVID-19 in Norway
PLoS Comput Biol, 20 (1), e1011426
DOI 10.1371/journal.pcbi.1011426, PubMed 38295111

Publications 2023

Cavalieri S, Vener C, LeBlanc M, Lopez-Perez L, Fico G, Resteghini C, Monzani D, Marton G, Pravettoni G, Moreira-Soares M, Filippidou DE, Almeida A, Bilbao A, Mehanna H, Singer S, Thomas S, Lacerenza L, Manfuso A, Copelli C, Mercalli F, Frigessi A, Martinelli E, Licitra L, BD4QoL Consortium (2023)
A multicenter randomized trial for quality of life evaluation by non-invasive intelligent tools during post-curative treatment follow-up for head and neck cancer: Clinical study protocol
Front Oncol, 13, 1048593
DOI 10.3389/fonc.2023.1048593, PubMed 36798825

Engebretsen S, Diz-Lois Palomares A, Rø G, Kristoffersen AB, Lindstrøm JC, Engø-Monsen K, Kamineni M, Hin Chan LY, Dale Ø, Midtbø JE, Stenerud KL, Di Ruscio F, White R, Frigessi A, de Blasio BF (2023)
A real-time regional model for COVID-19: Probabilistic situational awareness and forecasting
PLoS Comput Biol, 19 (1), e1010860
DOI 10.1371/journal.pcbi.1010860, PubMed 36689468

Kamineni M, Engø-Monsen K, Midtbø JE, Forland F, de Blasio BF, Frigessi A, Engebretsen S (2023)
Effects of non-compulsory and mandatory COVID-19 interventions on travel distance and time away from home, Norway, 2021
Euro Surveill, 28 (17)
DOI 10.2807/1560-7917.ES.2023.28.17.2200382, PubMed 37103789

Köhn-Luque A, Myklebust EM, Tadele DS, Giliberto M, Schmiester L, Noory J, Harivel E, Arsenteva P, Mumenthaler SM, Schjesvold F, Taskén K, Enserink JM, Leder K, Frigessi A, Foo J (2023)
Phenotypic deconvolution in heterogeneous cancer cell populations using drug-screening data
Cell Rep Methods, 3 (3), 100417
DOI 10.1016/j.crmeth.2023.100417, PubMed 37056380

Vitelli V, Fleischer T, Ankill J, Arjas E, Frigessi A, Kristensen VN, Zucknick M (2023)
Transcriptomic pan-cancer analysis using rank-based Bayesian inference
Mol Oncol, 17 (4), 548-563
DOI 10.1002/1878-0261.13354, PubMed 36562628

Wu C, Gunnarsson EB, Myklebust EM, Köhn-Luque A, Tadele DS, Enserink JM, Frigessi A, Foo J, Leder K (2023)
Using birth-death processes to infer tumor subpopulation structure from live-cell imaging drug screening data
PubMed 37396610

Publications 2022

Azulay N, Olsen RB, Nielsen CS, Stubhaug A, Jenssen TG, Schirmer H, Frigessi A, Rosseland LA, Tronstad C (2022)
Reduced heart rate variability is related to the number of metabolic syndrome components and manifest diabetes in the sixth Tromsø study 2007-2008
Sci Rep, 12 (1), 11998
DOI 10.1038/s41598-022-15824-0, PubMed 35835836

Jalali N, Brustad HK, Frigessi A, MacDonald EA, Meijerink H, Feruglio SL, Nygård KM, Rø G, Madslien EH, de Blasio BF (2022)
Increased household transmission and immune escape of the SARS-CoV-2 Omicron compared to Delta variants
Nat Commun, 13 (1), 5706
DOI 10.1038/s41467-022-33233-9, PubMed 36175424

Page CM, Nøst TH, Djordjilović V, Thoresen M, Frigessi A, Sandanger TM, Veierød MB (2022)
Pre-diagnostic DNA methylation in blood leucocytes in cutaneous melanoma; a nested case-control study within the Norwegian Women and Cancer cohort
Sci Rep, 12 (1), 14200
DOI 10.1038/s41598-022-18585-y, PubMed 35987900

Ravindran V, Wagoner J, Athanasiadis P, Den Hartigh AB, Sidorova JM, Ianevski A, Fink SL, Frigessi A, White J, Polyak SJ, Aittokallio T (2022)
Discovery of host-directed modulators of virus infection by probing the SARS-CoV-2-host protein-protein interaction network
Brief Bioinform, 23 (6)
DOI 10.1093/bib/bbac456, PubMed 36305426

Publications 2021

Divino F, Belay DB, Keilman N, Frigessi A (2021)
Spatial modelling of Lexis mortality data
Spat. Stat., 44, 100532
DOI 10.1016/j.spasta.2021.100532

Lai X, Taskén HA, Mo T, Funke SW, Frigessi A, Rognes ME, Köhn-Luque A (2021)
A scalable solver for a stochastic, hybrid cellular automaton model of personalized breast cancer therapy
Int J Numer Method Biomed Eng, 38 (1), e3542
DOI 10.1002/cnm.3542, PubMed 34716985

Lindstrøm JC, Engebretsen S, Kristoffersen AB, Rø GØI, Palomares AD, Engø-Monsen K, Madslien EH, Forland F, Nygård KM, Hagen F, Gantzel G, Wiklund O, Frigessi A, de Blasio BF (2021)
Increased transmissibility of the alpha SARS-CoV-2 variant: evidence from contact tracing data in Oslo, January to February 2021
Infect Dis (Lond), 54 (1), 72-77
DOI 10.1080/23744235.2021.1977382, PubMed 34618665

Publications 2020

Bergholtz H, Lien TG, Swanson DM, Frigessi A, Oslo Breast Cancer Research Consortium (OSBREAC), Daidone MG, Tost J, Wärnberg F, Sørlie T (2020)
Contrasting DCIS and invasive breast cancer by subtype suggests basal-like DCIS as distinct lesions
NPJ Breast Cancer, 6, 26
DOI 10.1038/s41523-020-0167-x, PubMed 32577501

Engebretsen S, Engø-Monsen K, Aleem MA, Gurley ES, Frigessi A, de Blasio BF (2020)
Time-aggregated mobile phone mobility data are sufficient for modelling influenza spread: the case of Bangladesh
J R Soc Interface, 17 (167), 20190809
DOI 10.1098/rsif.2019.0809, PubMed 32546112

Page CM, Djordjilović V, Nøst TH, Ghiasvand R, Sandanger TM, Frigessi A, Thoresen M, Veierød MB (2020)
Lifetime Ultraviolet Radiation Exposure and DNA Methylation in Blood Leukocytes: The Norwegian Women and Cancer Study
Sci Rep, 10 (1), 4521
DOI 10.1038/s41598-020-61430-3, PubMed 32161338

Pladsen AV, Nilsen G, Rueda OM, Aure MR, Borgan Ø, Liestøl K, Vitelli V, Frigessi A, Langerød A, Mathelier A, OSBREAC, Engebråten O, Kristensen V, Wedge DC, Van Loo P, Caldas C, Børresen-Dale AL, Russnes HG, Lingjærde OC (2020)
DNA copy number motifs are strong and independent predictors of survival in breast cancer
Commun Biol, 3 (1), 153
DOI 10.1038/s42003-020-0884-6, PubMed 32242091

Publications 2019

Crispino M, Arjas E, Vitelli V, Barrett N, Frigessi A (2019)
Ann. Appl. Stat., 13 (1), 492-519
DOI 10.1214/18-AOAS1203

Engebretsen S, Engø-Monsen K, Frigessi A, Freiesleben de Blasio B (2019)
A theoretical single-parameter model for urbanisation to study infectious disease spread and interventions
PLoS Comput Biol, 15 (3), e1006879
DOI 10.1371/journal.pcbi.1006879, PubMed 30845153

Lai X, Geier OM, Fleischer T, Garred Ø, Borgen E, Funke SW, Kumar S, Rognes ME, Seierstad T, Børresen-Dale AL, Kristensen VN, Engebraaten O, Köhn-Luque A, Frigessi A (2019)
Toward Personalized Computer Simulation of Breast Cancer Treatment: A Multiscale Pharmacokinetic and Pharmacodynamic Model Informed by Multitype Patient Data
Cancer Res, 79 (16), 4293-4304
DOI 10.1158/0008-5472.CAN-18-1804, PubMed 31118201

Liu QH, Crispino M, Scheel I, Vitelli V, Frigessi A (2019)
Model-Based Learning from Preference Data
ANNU REV STAT APPL, 6, 329-354
DOI 10.1146/annurev-statistics-031017-100213

Liu QH, Reiner AH, Frigessi A, Scheel I (2019)
Diverse personalized recommendations with uncertainty from implicit preference data with the Bayesian Mallows model
Knowledge-Based Syst., 186, 104960
DOI 10.1016/j.knosys.2019.104960

Swanson DM, Lien T, Bergholtz H, Sørlie T, Frigessi A (2019)
A Bayesian two-way latent structure model for genomic data integration reveals few pan-genomic cluster subtypes in a breast cancer cohort
Bioinformatics, 35 (23), 4886-4897
DOI 10.1093/bioinformatics/btz381, PubMed 31077301

Tekpli X, Lien T, Røssevold AH, Nebdal D, Borgen E, Ohnstad HO, Kyte JA, Vallon-Christersson J, Fongaard M, Due EU, Svartdal LG, Sveli MAT, Garred Ø, OSBREAC, Frigessi A, Sahlberg KK, Sørlie T, Russnes HG, Naume B, Kristensen VN (2019)
An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment
Nat Commun, 10 (1), 5499
DOI 10.1038/s41467-019-13329-5, PubMed 31796750

Publications 2018

Engebretsen S, Frigessi A, Engø-Monsen K, Furberg AS, Stubhaug A, de Blasio BF, Nielsen CS (2018)
The peer effect on pain tolerance
Scand J Pain, 18 (3), 467-477
DOI 10.1515/sjpain-2018-0060, PubMed 29794275

Erango M, Frigessi A, Rosseland LA (2018)
A three minutes supine position test reveals higher risk of spinal anesthesia induced hypotension during cesarean delivery. An observational study
F1000Res, 7, 1028
DOI 10.12688/f1000research.15142.1, PubMed 30135733

LeBlanc M, Zuber V, Thompson WK, Andreassen OA, Schizophrenia and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, Frigessi A, Andreassen BK (2018)
A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework
BMC Genomics, 19 (1), 494
DOI 10.1186/s12864-018-4859-7, PubMed 29940862

Rohrbeck C, Costain DA, Frigessi A (2018)
Bayesian spatial monotonic multiple regression
Biometrika, 105 (3), 691-707
DOI 10.1093/biomet/asy019

Rohrbeck C, Eastoe EF, Frigessi A, Tawn JA (2018)
Ann. Appl. Stat., 12 (1), 246-282
DOI 10.1214/17-AOAS1081

Sorensen O, Hellton KH, Frigessi A, Thoresen M (2018)
Covariate Selection in High-Dimensional Generalized Linear Models With Measurement Error
J. Comput. Graph. Stat., 27 (4), 739-749
DOI 10.1080/10618600.2018.1425626

Vitelli V, Sorensen O, Crispino M, Frigessi A, Arjas E (2018)
Probabilistic preference learning with the Mallows rank model
J. Mach. Learn. Res., 18, 1-49

Publications 2017

Asfaw D, Vitelli V, Sorensen O, Arjas E, Frigessi A (2017)
Time-varying rankings with the Bayesian Mallows model
Stat, 6 (1), 14-30
DOI 10.1002/sta4.132

Aure MR, Vitelli V, Jernström S, Kumar S, Krohn M, Due EU, Haukaas TH, Leivonen SK, Vollan HK, Lüders T, Rødland E, Vaske CJ, Zhao W, Møller EK, Nord S, Giskeødegård GF, Bathen TF, Caldas C, Tramm T, Alsner J, Overgaard J, Geisler J, Bukholm IR, Naume B, Schlichting E et al. (2017)
Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome
Breast Cancer Res, 19 (1), 44
DOI 10.1186/s13058-017-0812-y, PubMed 28356166

Belay DB, Kifle YG, Goshu AT, Gran JM, Yewhalaw D, Duchateau L, Frigessi A (2017)
Joint Bayesian modeling of time to malaria and mosquito abundance in Ethiopia
BMC Infect Dis, 17 (1), 415
DOI 10.1186/s12879-017-2496-4, PubMed 28606100

Fleischer T, Tekpli X, Mathelier A, Wang S, Nebdal D, Dhakal HP, Sahlberg KK, Schlichting E, Oslo Breast Cancer Research Consortium (OSBREAC), Børresen-Dale AL, Borgen E, Naume B, Eskeland R, Frigessi A, Tost J, Hurtado A, Kristensen VN (2017)
DNA methylation at enhancers identifies distinct breast cancer lineages
Nat Commun, 8 (1), 1379
DOI 10.1038/s41467-017-00510-x, PubMed 29123100

Linder MD, Frigessi A, Piaserico S, Keilman N (2017)
Simulating the life course of psoriasis patients: the interplay between therapy intervention and marital status
J Eur Acad Dermatol Venereol, 32 (1), 62-67
DOI 10.1111/jdv.14567, PubMed 28850745

Publications 2016

Haff IH, Aas K, Frigessi A, Lacal V (2016)
Structure learning in Bayesian Networks using regular vines
Comput. Stat. Data Anal., 101, 186-208
DOI 10.1016/j.csda.2016.03.003

Solvang HK, Frigessi A, Kaveh F, Riis ML, Lüders T, Bukholm IR, Kristensen VN, Andreassen BK (2016)
Gene expression analysis supports tumor threshold over 2.0 cm for T-category breast cancer
EURASIP J Bioinform Syst Biol, 2016 (1), 6
DOI 10.1186/s13637-015-0034-5, PubMed 26900390

Tharmaratnam K, Sperrin M, Jaki T, Reppe S, Frigessi A (2016)
Tilting the lasso by knowledge-based post-processing
BMC Bioinformatics, 17 (1), 344
DOI 10.1186/s12859-016-1210-7, PubMed 27590269

Publications 2015

Frigessi A, Holden L, Teigland A (2015)
(sfi)(2) Statistics for Innovation - The experience of the Oslo centre in industrial statistics
Appl. Stoch. Models. Bus. Ind., 31 (1), 82-93
DOI 10.1002/asmb.2113

Frigessi A, Holden L, Teigland A (2015)
Rejoinder to '(sfi)(2) Statistics for Innovation The experience of the Oslo centre in industrial statistics'
Appl. Stoch. Models. Bus. Ind., 31 (1), 96
DOI 10.1002/asmb.2114

Haff IH, Frigessi A, Maraun D (2015)
How well do regional climate models simulate the spatial dependence of precipitation? An application of pair-copula constructions
J. Geophys. Res.-Atmos., 120 (7), 2624-2646
DOI 10.1002/2014JD022748

LeBlanc M, Zuber V, Andreassen BK, Witoelar A, Zeng L, Bettella F, Wang Y, McEvoy LK, Thompson WK, Schork AJ, Reppe S, Barrett-Connor E, Ligthart S, Dehghan A, Gautvik KM, Nelson CP, Schunkert H, Samani NJ, CARDIoGRAM Consortium, Ridker PM, Chasman DI, Aukrust P, Djurovic S, Frigessi A, Desikan RS et al. (2015)
Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors
Circ Res, 118 (1), 83-94
DOI 10.1161/CIRCRESAHA.115.306629, PubMed 26487741

Sorensen O, Frigessi A, Thoresen M (2015)
Stat. Sin., 25 (2), 809-829
DOI 10.5705/ss.2013.180

Publications 2014

Fairbairn CE, Sayette MA, Aalen OO, Frigessi A (2014)
Alcohol and Emotional Contagion: An Examination of the Spreading of Smiles in Male and Female Drinking Groups
Clin Psychol Sci, 3 (5), 686-701
DOI 10.1177/2167702614548892, PubMed 26504673

Fleischer T, Frigessi A, Johnson KC, Edvardsen H, Touleimat N, Klajic J, Riis ML, Haakensen VD, Wärnberg F, Naume B, Helland A, Børresen-Dale AL, Tost J, Christensen BC, Kristensen VN (2014)
Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis
Genome Biol, 15 (8), 435
DOI 10.1186/PREACCEPT-2333349012841587, PubMed 25146004

Kristensen VN, Lingjærde OC, Russnes HG, Vollan HK, Frigessi A, Børresen-Dale AL (2014)
Principles and methods of integrative genomic analyses in cancer
Nat Rev Cancer, 14 (5), 299-313
DOI 10.1038/nrc3721, PubMed 24759209

Tramm T, Mohammed H, Myhre S, Kyndi M, Alsner J, Børresen-Dale AL, Sørlie T, Frigessi A, Overgaard J (2014)
Development and validation of a gene profile predicting benefit of postmastectomy radiotherapy in patients with high-risk breast cancer: a study of gene expression in the DBCG82bc cohort
Clin Cancer Res, 20 (20), 5272-80
DOI 10.1158/1078-0432.CCR-14-0458, PubMed 25149560

Publications 2013

Loland A, Huseby RB, Hjort NL, Frigessi A (2013)
Statistical Corrections of Invalid Correlation Matrices
Scand. J. Stat., 40 (4), 807-824
DOI 10.1111/sjos.12035

Sandve GK, Gundersen S, Johansen M, Glad IK, Gunathasan K, Holden L, Holden M, Liestøl K, Nygård S, Nygaard V, Paulsen J, Rydbeck H, Trengereid K, Clancy T, Drabløs F, Ferkingstad E, Kalas M, Lien T, Rye MB, Frigessi A, Hovig E (2013)
The Genomic HyperBrowser: an analysis web server for genome-scale data
Nucleic Acids Res, 41 (Web Server issue), W133-41
DOI 10.1093/nar/gkt342, PubMed 23632163

Scheel I, Ferkingstad E, Frigessi A, Haug O, Hinnerichsen M, Meze-Hausken E (2013)
A Bayesian hierarchical model with spatial variable selection: the effect of weather on insurance claims
J R Stat Soc Ser C Appl Stat, 62 (1), 85-100
DOI 10.1111/j.1467-9876.2012.01039.x, PubMed 23396890

Publications 2012

Aldrin M, Raastad R, Tvete IF, Berild D, Frigessi A, Leegaard T, Monnet DL, Walberg M, Müller F (2012)
Antibiotic resistance in hospitals: a ward-specific random effect model in a low antibiotic consumption environment
Stat Med, 32 (8), 1407-18
DOI 10.1002/sim.5636, PubMed 23027651

Brown AA, Jensen J, Nikolova YS, Djurovic S, Agartz I, Server A, Ferrell RE, Manuck SB, Mattingsdal M, Melle I, Hariri AR, Frigessi A, Andreassen OA (2012)
Genetic variants affecting the neural processing of human facial expressions: evidence using a genome-wide functional imaging approach
Transl Psychiatry, 2 (7), e143
DOI 10.1038/tp.2012.67, PubMed 22828495

Joshi H, Nord SH, Frigessi A, Børresen-Dale AL, Kristensen VN (2012)
Overrepresentation of transcription factor families in the genesets underlying breast cancer subtypes
BMC Genomics, 13, 199
DOI 10.1186/1471-2164-13-199, PubMed 22616941

Villani A, Frigessi A, Liljeros F, Nordvik MK, de Blasio BF (2012)
A characterization of internet dating network structures among nordic men who have sex with men
PLoS One, 7 (7), e39717
DOI 10.1371/journal.pone.0039717, PubMed 22808052

Publications 2011

Ambrosi A, Glad IK, Pellin D, Cattoglio C, Mavilio F, Di Serio C, Frigessi A (2011)
Estimated comparative integration hotspots identify different behaviors of retroviral gene transfer vectors
PLoS Comput Biol, 7 (12), e1002292
DOI 10.1371/journal.pcbi.1002292, PubMed 22144885

Frigessi A, Loland A, Pievatolo A, Ruggeri F (2011)
Statistical rehabilitation of improper correlation matrices
Quant. Financ., 11 (7), 1081-1090
DOI 10.1080/14697680903390118

Gundersen S, Kalaš M, Abul O, Frigessi A, Hovig E, Sandve GK (2011)
Identifying elemental genomic track types and representing them uniformly
BMC Bioinformatics, 12, 494
DOI 10.1186/1471-2105-12-494, PubMed 22208806

Jemtland R, Holden M, Reppe S, Olstad OK, Reinholt FP, Gautvik VT, Refvem H, Frigessi A, Houston B, Gautvik KM (2011)
Molecular disease map of bone characterizing the postmenopausal osteoporosis phenotype
J Bone Miner Res, 26 (8), 1793-801
DOI 10.1002/jbmr.396, PubMed 21452281

LeBlanc M, Kulle B, Sundet K, Agartz I, Melle I, Djurovic S, Frigessi A, Andreassen OA (2011)
Genome-wide study identifies PTPRO and WDR72 and FOXQ1-SUMO1P1 interaction associated with neurocognitive function
J Psychiatr Res, 46 (2), 271-8
DOI 10.1016/j.jpsychires.2011.11.001, PubMed 22126837

Orskaug E, Scheel I, Frigessi A, Guttorp P, Haugen JE, Tveito OE, Haug O (2011)
Evaluation of a dynamic downscaling of precipitation over the Norwegian mainland
Tellus Ser. A-Dyn. Meteorol. Oceanol., 63 (4), 746-756
DOI 10.1111/j.1600-0870.2011.00525.x

Sandve GK, Gundersen S, Rydbeck H, Glad IK, Holden L, Holden M, Liestøl K, Clancy T, Drabløs F, Ferkingstad E, Johansen M, Nygaard V, Tøstesen E, Frigessi A, Hovig E (2011)
The differential disease regulome
BMC Genomics, 12, 353
DOI 10.1186/1471-2164-12-353, PubMed 21736759

Solvang HK, Lingjærde OC, Frigessi A, Børresen-Dale AL, Kristensen VN (2011)
Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in breast cancer
BMC Bioinformatics, 12, 197
DOI 10.1186/1471-2105-12-197, PubMed 21609452

Zhao X, Rødland EA, Sørlie T, Naume B, Langerød A, Frigessi A, Kristensen VN, Børresen-Dale AL, Lingjærde OC (2011)
Combining gene signatures improves prediction of breast cancer survival
PLoS One, 6 (3), e17845
DOI 10.1371/journal.pone.0017845, PubMed 21423775

Publications 2010

Haff IH, Aas K, Frigessi A (2010)
On the simplified pair-copula construction - Simply useful or too simplistic?
J. Multivar. Anal., 101 (5), 1296-1310
DOI 10.1016/j.jmva.2009.12.001

Myhre S, Mohammed H, Tramm T, Alsner J, Finak G, Park M, Overgaard J, Børresen-Dale AL, Frigessi A, Sørlie T (2010)
In silico ascription of gene expression differences to tumor and stromal cells in a model to study impact on breast cancer outcome
PLoS One, 5 (11), e14002
DOI 10.1371/journal.pone.0014002, PubMed 21124964

Sandve GK, Gundersen S, Rydbeck H, Glad IK, Holden L, Holden M, Liestøl K, Clancy T, Ferkingstad E, Johansen M, Nygaard V, Tøstesen E, Frigessi A, Hovig E (2010)
The Genomic HyperBrowser: inferential genomics at the sequence level
Genome Biol, 11 (12), R121
DOI 10.1186/gb-2010-11-12-r121, PubMed 21182759

Publications 2009

Aldrin M, Storvik B, Frigessi A, Viljugrein H, Jansen PA (2009)
A stochastic model for the assessment of the transmission pathways of heart and skeleton muscle inflammation, pancreas disease and infectious salmon anaemia in marine fish farms in Norway
Prev Vet Med, 93 (1), 51-61
DOI 10.1016/j.prevetmed.2009.09.010, PubMed 19811843

Lawyer G, Nesvag R, Varnas K, Frigessi A, Agartz I (2009)
Investigating possible subtypes of schizophrenia patients and controls based on brain cortical thickness (vol 164, pg 254, 2008)
Psychiatry Res. Neuroimaging, 171 (3), 258
DOI 10.1016/j.pscychresns.2008.12.001

Reppe S, Refvem H, Gautvik VT, Olstad OK, Høvring PI, Reinholt FP, Holden M, Frigessi A, Jemtland R, Gautvik KM (2009)
Eight genes are highly associated with BMD variation in postmenopausal Caucasian women
Bone, 46 (3), 604-12
DOI 10.1016/j.bone.2009.11.007, PubMed 19922823

Aas K, Czado C, Frigessi A, Bakken H (2009)
Pair-copula constructions of multiple dependence
Insur. Math. Econ., 44 (2), 182-198
DOI 10.1016/j.insmatheco.2007.02.001

Publications 2008

Ferkingstad E, Frigessi A, Lyng H (2008)
Indirect genomic effects on survival from gene expression data
Genome Biol, 9 (3), R58
DOI 10.1186/gb-2008-9-3-r58, PubMed 18358079

Ferkingstad E, Frigessi A, Rue H, Thorleifsson G, Kong A (2008)
Ann. Appl. Stat., 2 (2), 714-735
DOI 10.1214/08-AOAS158

Husberg C, Nygård S, Finsen AV, Damås JK, Frigessi A, Oie E, Waehre A, Gullestad L, Aukrust P, Yndestad A, Christensen G (2008)
Cytokine expression profiling of the myocardium reveals a role for CX3CL1 (fractalkine) in heart failure
J Mol Cell Cardiol, 45 (2), 261-9
DOI 10.1016/j.yjmcc.2008.05.009, PubMed 18585734

Kulle B, Frigessi A, Edvardsen H, Kristensen V, Wojnowski L (2008)
Accounting for haplotype phase uncertainty in linkage disequilibrium estimation
Genet Epidemiol, 32 (2), 168-78
DOI 10.1002/gepi.20273, PubMed 17968987

Kulle B, Frigessi A, Edvardsen H, Kristensen V, Wojnowski L (2008)
Accounting for haplotype phase uncertainty in linkage disequilibrium estimation (vol 32, pg 168, 2008)
Genet. Epidemiol., 32 (6), 586-587
DOI 10.1002/gepi.20332

Lawyer G, Nesvåg R, Varnäs K, Frigessi A, Agartz I (2008)
Investigating possible subtypes of schizophrenia patients and controls based on brain cortical thickness
Psychiatry Res, 164 (3), 254-64
DOI 10.1016/j.pscychresns.2007.12.017, PubMed 19022629

Nygaard V, Liu F, Holden M, Kuo WP, Trimarchi J, Ohno-Machado L, Cepko CL, Frigessi A, Glad IK, Wiel MA, Hovig E, Lyng H (2008)
Validation of oligoarrays for quantitative exploration of the transcriptome
BMC Genomics, 9, 258
DOI 10.1186/1471-2164-9-258, PubMed 18513391

Publications 2007

Bøvelstad HM, Nygård S, Størvold HL, Aldrin M, Borgan Ø, Frigessi A, Lingjaerde OC (2007)
Predicting survival from microarray data--a comparative study
Bioinformatics, 23 (16), 2080-7
DOI 10.1093/bioinformatics/btm305, PubMed 17553857

Kausrud KL, Viljugrein H, Frigessi A, Begon M, Davis S, Leirs H, Dubyanskiy V, Stenseth NC (2007)
Climatically driven synchrony of gerbil populations allows large-scale plague outbreaks
Proc Biol Sci, 274 (1621), 1963-9
DOI 10.1098/rspb.2007.0568, PubMed 17550884

Nesvåg R, Frigessi A, Jönsson EG, Agartz I (2007)
Effects of alcohol consumption and antipsychotic medication on brain morphology in schizophrenia
Schizophr Res, 90 (1-3), 52-61
DOI 10.1016/j.schres.2006.11.008, PubMed 17218084

Nesvåg R, Lawyer G, Varnäs K, Fjell AM, Walhovd KB, Frigessi A, Jönsson EG, Agartz I (2007)
Regional thinning of the cerebral cortex in schizophrenia: effects of diagnosis, age and antipsychotic medication
Schizophr Res, 98 (1-3), 16-28
DOI 10.1016/j.schres.2007.09.015, PubMed 17933495

Scheel I, Aldrin M, Frigessi A, Jansen PA (2007)
A stochastic model for infectious salmon anemia (ISA) in Atlantic salmon farming
J R Soc Interface, 4 (15), 699-706
DOI 10.1098/rsif.2007.0217, PubMed 17301014

Aalen OO, Frigessi A (2007)
What can statistics contribute to a causal understanding?
Scand. J. Stat., 34 (1), 155-168
DOI 10.1111/j.1467-9469.2006.00549.x

Publications 2006

Agartz I, Sedvall GC, Terenius L, Kulle B, Frigessi A, Hall H, Jönsson EG (2006)
BDNF gene variants and brain morphology in schizophrenia
Am J Med Genet B Neuropsychiatr Genet, 141B (5), 513-23
DOI 10.1002/ajmg.b.30338, PubMed 16741916

Jönsson EG, Edman-Ahlbom B, Sillén A, Gunnar A, Kulle B, Frigessi A, Vares M, Ekholm B, Wode-Helgodt B, Schumacher J, Cichon S, Agartz I, Sedvall GC, Hall H, Terenius L (2006)
Brain-derived neurotrophic factor gene (BDNF) variants and schizophrenia: an association study
Prog Neuropsychopharmacol Biol Psychiatry, 30 (5), 924-33
DOI 10.1016/j.pnpbp.2006.02.008, PubMed 16581172

Perminow G, Frigessi A, Rydning A, Nakstad B, Vatn MH (2006)
Incidence and clinical presentation of IBD in children: comparison between prospective and retrospective data in a selected Norwegian population
Scand J Gastroenterol, 41 (12), 1433-9
DOI 10.1080/00365520600789891, PubMed 17101574

Publications 2005

Frigessi A, Holden M, Marshall C, Viljugrein H, Stenseth NC, Holden L, Ageyev V, Klassovskiy NL (2005)
Bayesian population dynamics of interacting species: great gerbils and fleas in Kazakhstan
Biometrics, 61 (1), 230-8
DOI 10.1111/j.0006-341X.2005.030536.x, PubMed 15737098

Frigessi A, van de Wiel MA, Holden M, Svendsrud DH, Glad IK, Lyng H (2005)
Genome-wide estimation of transcript concentrations from spotted cDNA microarray data
Nucleic Acids Res, 33 (17), e143
DOI 10.1093/nar/gni141, PubMed 16204447

Kristensen VN, Sørlie T, Geisler J, Yoshimura N, Linegjaerde OC, Glad I, Frigessi A, Harada N, Lønning PE, Børresen-Dale AL (2005)
Effects of anastrozole on the intratumoral gene expression in locally advanced breast cancer
J Steroid Biochem Mol Biol, 95 (1-5), 105-11
DOI 10.1016/j.jsbmb.2005.04.028, PubMed 16023338

Scheel I, Aldrin M, Glad IK, Sørum R, Lyng H, Frigessi A (2005)
The influence of missing value imputation on detection of differentially expressed genes from microarray data
Bioinformatics, 21 (23), 4272-9
DOI 10.1093/bioinformatics/bti708, PubMed 16216830

Publications 2004

Cekaite L, Haug O, Myklebost O, Aldrin M, Østenstad B, Holden M, Frigessi A, Hovig E, Sioud M (2004)
Analysis of the humoral immune response to immunoselected phage-displayed peptides by a microarray-based method
Proteomics, 4 (9), 2572-82
DOI 10.1002/pmic.200300768, PubMed 15352232

Frigessi A, Engel J (2004)
Editorial: a special ENBIS issue of SMIJ
Stat. Model., 4 (4), 245-247
DOI 10.1191/1471082X04st077ed

Heggland K, Frigessi A (2004)
Estimating functions in indirect inference
J. R. Stat. Soc. Ser. B-Stat. Methodol., 66, 447-462
DOI 10.1111/j.1369-7412.2003.05341.x

Saebø S, Frigessi A (2004)
A genetic and spatial Bayesian analysis of mastitis resistance
Genet Sel Evol, 36 (5), 527-42
DOI 10.1186/1297-9686-36-5-527, PubMed 15339631

Publications 2002

Frigessi A, Hjort NL (2002)
Statistical models and methods for discontinuous phenomena
J. Nonparametr. Stat., 14 (1-2), 1-5
DOI 10.1080/10485250211393

Hisdal H, Tallaksen LM, Frigessi A (2002)
Handling non-extreme events in extreme value modelling of streamflow droughts
IAHS-AISH P (274), 281-288

Storvik G, Frigessi A, Hirst D (2002)
Stationary space-time Gaussian fields and their time autoregressive representation
Stat. Model., 2 (2), 139-161
DOI 10.1191/1471082x02st029oa

Publications 2000

Davino F, Frigessi A, Green PJ (2000)
Penalized pseudolikelihood inference in spatial interaction models with covariates
Scand. J. Stat., 27 (3), 445-458

Frigessi A, Gasemyr J, Rue H (2000)
Antithetic coupling of two Gibbs sampler chains
Ann. Stat., 28 (4), 1128-1149

Perminow G, Rydning A, Jacobsen CD, Frigessi A (2000)
[Gastrointestinal endoscopy in children]
Tidsskr Nor Laegeforen, 120 (29), 3503-6
PubMed 11188374

Skare O, Benth FE, Frigessi A (2000)
Smoothed Langevin proposals in Metropolis-Hastings algorithms
Stat. Probab. Lett., 49 (4), 345-354
DOI 10.1016/S0167-7152(00)00067-5

Publications 1997

Frigessi A, Rue H (1997)
Bayesian image classification with Baddeley's delta loss
J. Comput. Graph. Stat., 6 (1), 55-73
DOI 10.2307/1390724

Publications 1994

Frigessi A, Lánský P, Mariotto AB (1994)
A stochastic model for neuronal bursting
Biosystems, 33 (1), 1-16
DOI 10.1016/0303-2647(94)90056-6, PubMed 7803696

Publications 1989

Frigessi A, den Hollander F (1989)
A stochastic model for the membrane potential of a stimulated neuron
J Math Biol, 27 (6), 681-92
DOI 10.1007/BF00276950, PubMed 2607222

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