Publications
Publications published since 2010 from OUS - Department of Microbiology
982 publications found
Publications 2024
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Vaccine responses and hybrid immunity in people living with HIV after SARS-CoV-2 breakthrough infections
NPJ Vaccines, 9 (1), 185
DOI 10.1038/s41541-024-00972-3, PubMed 39384763 -
Activity against Mycobacterium tuberculosis of a new class of spirooxindolopyrrolidine embedded chromanone hybrid heterocycles
RSC Adv, 14 (17), 11604-11613
DOI 10.1039/d4ra01501k, PubMed 38605893 -
Receipt of hepatitis E vaccine and fetal loss in rural Bangladesh: further analysis of a double-blind, cluster-randomised, controlled trial
Lancet Glob Health, 12 (8), e1300-e1311
DOI 10.1016/S2214-109X(24)00193-1, PubMed 39030061 -
Pulmonary comorbidities in people with HIV- the microbiome connection
Curr Opin HIV AIDS, 19 (5), 246-252
DOI 10.1097/COH.0000000000000871, PubMed 38935049 -
Elite controllers microbiome: unraveling the mystery of association and causation
Curr Opin HIV AIDS, 19 (5), 261-267
DOI 10.1097/COH.0000000000000867, PubMed 38874425 -
The balance between intrinsic and ecological fitness defines new regimes in eco-evolutionary population dynamics
bioRxiv
DOI 10.1101/2023.03.15.532871, PubMed 36993598 -
Escalated complement activation during hospitalization is associated with higher risk of 60-day mortality in SARS-CoV-2-infected patients
J Intern Med, 296 (1), 80-92
DOI 10.1111/joim.13783, PubMed 38539241 -
Hepatitis E vaccine and fetal loss: the potential pathophysiological basis - Authors' reply
Lancet Glob Health, 12 (11), e1760
DOI 10.1016/S2214-109X(24)00412-1, PubMed 39424567 -
Differential Abundance of Protein Acylation in Mycobacterium tuberculosis Under Exposure to Nitrosative Stress
Proteomics Clin Appl, 18 (6), e202300212
DOI 10.1002/prca.202300212, PubMed 39082596 -
Cellular immunity against cytomegalovirus and risk of infection after kidney transplantation
Front Immunol, 15, 1414830
DOI 10.3389/fimmu.2024.1414830, PubMed 39007131 -
Loss of alkyladenine DNA glycosylase alters gene expression in the developing mouse brain and leads to reduced anxiety and improved memory
DNA Repair (Amst), 135, 103632
DOI 10.1016/j.dnarep.2024.103632, PubMed 38280242 -
Executive deficits after SARS-CoV-2 infection: A cross-sectional population study
Brain Behav Immun Health, 41, 100857
DOI 10.1016/j.bbih.2024.100857, PubMed 39314761 -
Dissecting gene expression networks in the developing hippocampus through the lens of NEIL3 depletion
Prog Neurobiol, 235, 102599
DOI 10.1016/j.pneurobio.2024.102599, PubMed 38522610 -
No association between disease severity and respiratory syncytial virus subtypes RSV-A and RSV-B in hospitalized young children in Norway
PLoS One, 19 (3), e0298104
DOI 10.1371/journal.pone.0298104, PubMed 38466702 -
Identification of essential oils with strong activity against stationary phase Mycobacterium abscessus
Heliyon, 10 (5), e27073
DOI 10.1016/j.heliyon.2024.e27073, PubMed 38463856 -
Antimicrobial and Antibiofilm Effects of Bithionol against Mycobacterium abscessus
Antibiotics (Basel), 13 (6)
DOI 10.3390/antibiotics13060529, PubMed 38927195 -
'Bloodstream infection': A valuable concept we should keep in our toolbox
J Infect, 89 (4), 106236
DOI 10.1016/j.jinf.2024.106236, PubMed 39097005 -
Patient perspectives on infection prevention and control in cancer care: a survey of knowledge and attitudes among persons with cancer and their next of kin
J Hosp Infect, 146, 21-30
DOI 10.1016/j.jhin.2024.01.012, PubMed 38311296 -
Trends in the enterovirus surveillance in Oslo, Norway before and during the COVID-19 pandemic
Frontiers in Virology, 3, 1-9
DOI 10.3389/fviro.2023.1343781, PublikaID 492 -
Prospective Memory Assessment before and after Covid-19
N Engl J Med, 390 (9), 863-865
DOI 10.1056/NEJMc2311200, PubMed 38416436 -
Temporal trajectories of long-COVID symptoms in adults with 22 months follow-up in a prospective cohort study in Norway
Int J Infect Dis, 149, 107263 (in press)
DOI 10.1016/j.ijid.2024.107263, PubMed 39419167 -
Risk of death in Klebsiella pneumoniae bloodstream infections is associated with specific phylogenetic lineages
J Infect, 88 (5), 106155
DOI 10.1016/j.jinf.2024.106155, PubMed 38574775 -
Design and Synthesis of the Linezolid Bioisosteres to Resolve the Serotonergic Toxicity Associated with Linezolid
ACS Med Chem Lett, 15 (6), 924-937
DOI 10.1021/acsmedchemlett.4c00114, PubMed 38894926 -
ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA
Cell Rep, 43 (11), 114899 (in press)
DOI 10.1016/j.celrep.2024.114899, PubMed 39441717 -
Sex-specific DNA-replication in the early mammalian embryo
Nat Commun, 15 (1), 6323
DOI 10.1038/s41467-024-50727-w, PubMed 39060312 -
Meropenem pharmacokinetic/pharmacodynamic target attainment and clinical response in ICU patients: A prospective observational study
Acta Anaesthesiol Scand, 68 (4), 502-511
DOI 10.1111/aas.14376, PubMed 38286568 -
Role of tissue fluidization and topological defects in epithelial tubulogenesis
Phys. Rev. Research, 6 (2), 1-10
DOI 10.1103/PhysRevResearch.6.023315, PublikaID 494 -
Epigenetic aging of human blood cells is influenced by the age of the host body
Aging Cell, 23 (5), e14112
DOI 10.1111/acel.14112, PubMed 38439206 -
Circular RNA Profile in Atherosclerotic Disease: Regulation during ST-Elevated Myocardial Infarction
Int J Mol Sci, 25 (16)
DOI 10.3390/ijms25169014, PubMed 39201700 -
The combination of pleconaril, rupintrivir, and remdesivir efficiently inhibits enterovirus infections in vitro, delaying the development of drug-resistant virus variants
Antiviral Res, 224, 105842
DOI 10.1016/j.antiviral.2024.105842, PubMed 38417531 -
Exploring the gut DNA virome in fecal immunochemical test stool samples reveals associations with lifestyle in a large population-based study
Nat Commun, 15 (1), 1791
DOI 10.1038/s41467-024-46033-0, PubMed 38424056 -
Clinical trial: An open-label, randomised trial of different re-start strategies after treatment withdrawal in HBeAg negative chronic hepatitis B
Aliment Pharmacol Ther, 60 (4), 434-445
DOI 10.1111/apt.18147, PubMed 38970293 -
Emergence of enterovirus D68 in a Norwegian paediatric population 2012-2022
Frontiers in Virology, 4, 1-7
DOI 10.3389/fviro.2024.1358963, PublikaID 493 -
Unravelling the complexities of resistance mechanism in pancreatic cancer: Insights from in vitro and ex-vivo model systems
Semin Cancer Biol, 106-107, 217-233 (in press)
DOI 10.1016/j.semcancer.2024.09.002, PubMed 39299411 -
Topology-guided polar ordering of collective cell migration
Sci Adv, 10 (16), eadk4825
DOI 10.1126/sciadv.adk4825, PubMed 38630812 -
Virologic Response and Reinfection Following HCV Treatment among Hospitalized People Who Inject Drugs: Follow-Up Data from the OPPORTUNI-C Trial
Viruses, 16 (6)
DOI 10.3390/v16060858, PubMed 38932151 -
Clinical Evaluation of the VirClia IgM/IgG Chemiluminescence Tests for the Diagnosis of Tick-Borne Encephalitis in an Endemic Part of Norway
Viruses, 16 (9)
DOI 10.3390/v16091505, PubMed 39339981 -
Estimating vaccine effectiveness against COVID-19 using cause-specific sick leave as an indicator: a nationwide population-based cohort study, Norway, July 2021 - December 2022
BMC Public Health, 24 (1), 1861
DOI 10.1186/s12889-024-19374-0, PubMed 38992631 -
Modeling the relative influence of socio-demographic variables on post-acute COVID-19 quality of life
medRxiv
DOI 10.1101/2024.02.21.24303099, PubMed 39040190 -
Opportunistic Treatment of Hepatitis C Infection Among Hospitalized People Who Inject Drugs (OPPORTUNI-C): A Stepped Wedge Cluster Randomized Trial
Clin Infect Dis, 78 (3), 582-590
DOI 10.1093/cid/ciad711, PubMed 37992203 -
Depletion of the m1A writer TRMT6/TRMT61A reduces proliferation and resistance against cellular stress in bladder cancer
Front Oncol, 13, 1334112
DOI 10.3389/fonc.2023.1334112, PubMed 38304034 -
Enhanced glutathione levels confer resistance to apoptotic and ferroptotic programmed cell death in NEIL DNA glycosylase deficient HAP1 cells
Free Radic Biol Med, 213, 470-487
DOI 10.1016/j.freeradbiomed.2024.01.037, PubMed 38301978 -
Microbial exposure during early life regulates development of bile duct inflammation
Scand J Gastroenterol, 59 (2), 192-201
DOI 10.1080/00365521.2023.2278423, PubMed 37997753 -
Predominance of multidrug-resistant Salmonella Typhi genotype 4.3.1 with low-level ciprofloxacin resistance in Zanzibar
PLoS Negl Trop Dis, 18 (4), e0012132
DOI 10.1371/journal.pntd.0012132, PubMed 38630840 -
Cancer pathways may be too rushed
Tidsskr Nor Laegeforen, 144 (13)
DOI 10.4045/tidsskr.24.0467, PubMed 39498646 -
Long Covid: a global health issue - a prospective, cohort study set in four continents
BMJ Glob Health, 9 (10)
DOI 10.1136/bmjgh-2024-015245, PubMed 39433402 -
Complete response of metastatic microsatellite-stable BRAF V600E colorectal cancer to first-line oxaliplatin-based chemotherapy and immune checkpoint blockade
Oncoimmunology, 13 (1), 2372886
DOI 10.1080/2162402X.2024.2372886, PubMed 38952672 -
Bacterial growth in patients with low back pain and Modic changes: protocol of a multicentre, case-control biopsy study
BMJ Open, 14 (5), e082244
DOI 10.1136/bmjopen-2023-082244, PubMed 38719329 -
A monoallelic UXS1 variant associated with short-limbed short stature
Mol Genet Genomic Med, 12 (6), e2472
DOI 10.1002/mgg3.2472, PubMed 38860481 -
Molecular epidemiology of Streptococcus pneumoniae isolates causing invasive and noninvasive infection in Ethiopia
Sci Rep, 14 (1), 21409
DOI 10.1038/s41598-024-72762-9, PubMed 39271789 -
Epidemiological and Clinical Insights into the Enterovirus D68 Upsurge in Europe 2021-2022 and Emergence of Novel B3-Derived Lineages, ENPEN Multicentre Study
J Infect Dis, 230 (4), e917-e928
DOI 10.1093/infdis/jiae154, PubMed 38547499 -
Clinical characteristics and factors affecting disease severity in hospitalized tick-borne encephalitis patients in Norway from 2018 to 2022
Eur J Clin Microbiol Infect Dis, 43 (7), 1355-1366
DOI 10.1007/s10096-024-04855-2, PubMed 38801484 -
The yeast genus Tardiomyces gen. nov. with one new species and two new combinations
Infection, 52 (5), 1799-1812
DOI 10.1007/s15010-024-02229-6, PubMed 38573472 -
Post-COVID-19 condition symptoms 6-12 months after hospitalisation in Wuhan
Lancet, 403 (10434), 1336
DOI 10.1016/S0140-6736(24)00414-8, PubMed 38582558 -
Cryptosporidium species and subtypes in Norway: predominance of C. parvum and emergence of C. mortiferum
Emerg Microbes Infect, 13 (1), 2412624
DOI 10.1080/22221751.2024.2412624, PubMed 39361548 -
Nicotinamide riboside first alleviates symptoms but later downregulates dopamine metabolism in proteasome inhibition mouse model of Parkinson's disease
Heliyon, 10 (14), e34355
DOI 10.1016/j.heliyon.2024.e34355, PubMed 39108921 -
High viral loads combined with inflammatory markers predict disease severity in hospitalized COVID-19 patients: Results from the NOR-Solidarity trial
J Intern Med, 296 (3), 249-259
DOI 10.1111/joim.13820, PubMed 39011800 -
Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies
J Gerontol A Biol Sci Med Sci, 79 (4)
DOI 10.1093/gerona/glae029, PubMed 38289789 -
Predicting regulatory mutations and their target genes by new computational integrative analysis: A study of follicular lymphoma
Comput Biol Med, 178, 108787
DOI 10.1016/j.compbiomed.2024.108787, PubMed 38901187 -
Prevalence and Characteristics of Plasmid-Encoded Serine Protease EspP in Clinical Shiga Toxin-Producing Escherichia coli Strains from Patients in Sweden
Microorganisms, 12 (3)
DOI 10.3390/microorganisms12030589, PubMed 38543640 -
Seroprevalence of SARS-CoV-2 and humoral immune responses to COVID-19 mRNA vaccines among people who use drugs - in the light of tailored mitigating strategies
Harm Reduct J, 21 (1), 120
DOI 10.1186/s12954-024-01023-9, PubMed 38890611 -
Altered Genome-Wide DNA Methylation in the Duodenum of Common Variable Immunodeficiency Patients
J Clin Immunol, 44 (6), 133
DOI 10.1007/s10875-024-01726-5, PubMed 38780872 -
Characterization of Escherichia coli strains producing Shiga Toxin 2f subtype from domestic Pigeon
Sci Rep, 14 (1), 24481
DOI 10.1038/s41598-024-76523-6, PubMed 39424949 -
A novel multiscale framework for delineating cancer evolution from subclonal compositions
J Theor Biol, 582, 111743
DOI 10.1016/j.jtbi.2024.111743, PubMed 38307450 -
Safety and effectiveness of a recombinant hepatitis E vaccine in women of childbearing age in rural Bangladesh: a phase 4, double-blind, cluster-randomised, controlled trial
Lancet Glob Health, 12 (8), e1288-e1299
DOI 10.1016/S2214-109X(24)00192-X, PubMed 39030060 -
Genetic diversity and potential transmission of Escherichia albertii in a poultry breeding rural village
Jpn J Infect Dis (in press)
DOI 10.7883/yoken.JJID.2024.209, PubMed 39343555 -
Decreased in Mitochondrial Complex I Subunit NDUFS2 Is Critical for Oocyte Quality During Postovulatory Aging in Pigs
Microsc Microanal, 30 (5), 953-961
DOI 10.1093/mam/ozae079, PubMed 39226079 -
GRK2 is critical for the cleavage of the porcine embryo by regulating HSP90 and the AKT pathway
Reproduction, 168 (4)
DOI 10.1530/REP-23-0463, PubMed 39051904 -
Incidence and outcome of COVID-19 following vaccine and hybrid immunity in patients on immunosuppressive therapy: identification of protective post-immunisation anti-RBD antibody levels in a prospective cohort study
RMD Open, 10 (2)
DOI 10.1136/rmdopen-2023-003545, PubMed 38599653
Publications 2023
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The population structure of vancomycin-resistant and -susceptible Enterococcus faecium in a low-prevalence antimicrobial resistance setting is highly influenced by circulating global hospital-associated clones
Microb Genom, 9 (12)
DOI 10.1099/mgen.0.001160, PubMed 38112685 -
The first vanE-type vancomycin resistant Enterococcus faecalis isolates in Norway - phenotypic and molecular characteristics
J Glob Antimicrob Resist, 36, 193-199
DOI 10.1016/j.jgar.2023.12.021, PubMed 38154751 -
Optimized synthesis of polyacrylic acid-coated magnetic nanoparticles for high-efficiency DNA isolation and size selection
RSC Adv, 13 (42), 29109-29120
DOI 10.1039/d3ra04687g, PubMed 37800135 -
Long-term neurological symptoms after acute COVID-19 illness requiring hospitalization in adult patients: insights from the ISARIC-COVID-19 follow-up study
J Neurol, 271 (1), 79-86
DOI 10.1007/s00415-023-12133-y, PubMed 38055020 -
Cytomegalovirus High-risk Kidney Transplant Recipients Show No Difference in Long-term Outcomes Following Preemptive Versus Prophylactic Management
Transplantation, 107 (8), 1846-1853
DOI 10.1097/TP.0000000000004615, PubMed 37211633 -
Improvement in Neisseria gonorrhoeae culture rates by bedside inoculation and incubation at a clinic for sexually transmitted infections
Ann Clin Microbiol Antimicrob, 22 (1), 27
DOI 10.1186/s12941-023-00576-0, PubMed 37072830 -
Implementation of Recommendations on the Use of Corticosteroids in Severe COVID-19
JAMA Netw Open, 6 (12), e2346502
DOI 10.1001/jamanetworkopen.2023.46502, PubMed 38147336 -
Neurological manifestations of COVID-19 in adults and children
Brain, 146 (4), 1648-1661
DOI 10.1093/brain/awac332, PubMed 36087305 -
The Role of Procalcitonin as an Antimicrobial Stewardship Tool in Patients Hospitalized with Seasonal Influenza
Antibiotics (Basel), 12 (3)
DOI 10.3390/antibiotics12030573, PubMed 36978440 -
SigH stress response mediates killing of Mycobacterium tuberculosis by activating nitronaphthofuran prodrugs via induction of Mrx2 expression
Nucleic Acids Res, 51 (1), 144-165
DOI 10.1093/nar/gkac1173, PubMed 36546765 -
Fourier transform infrared spectroscopy; can it be used as a rapid typing method of Neisseria gonorrhoeae?
J Microbiol Methods, 205, 106675
DOI 10.1016/j.mimet.2023.106675, PubMed 36681126 -
A second update on mapping the human genetic architecture of COVID-19
Nature, 621 (7977), E7-E26
DOI 10.1038/s41586-023-06355-3, PubMed 37674002 -
The epidemiology of multidrug-resistant organisms in persons diagnosed with cancer in Norway, 2008-2018: expanding surveillance using existing laboratory and register data
Eur J Clin Microbiol Infect Dis, 43 (1), 121-132
DOI 10.1007/s10096-023-04698-3, PubMed 37980302 -
Clinical outcomes of antimicrobial resistance in cancer patients: a systematic review of multivariable models
BMC Infect Dis, 23 (1), 247
DOI 10.1186/s12879-023-08182-3, PubMed 37072711 -
The Local Tumor Microbiome Is Associated with Survival in Late-Stage Colorectal Cancer Patients
Microbiol Spectr, 11 (3), e0506622
DOI 10.1128/spectrum.05066-22, PubMed 37042765 -
Antibiotic Consumption in a Cohort of Hospitalized Adults with Viral Respiratory Tract Infection
Antibiotics (Basel), 12 (4)
DOI 10.3390/antibiotics12040788, PubMed 37107150 -
Human APOBEC3B promotes tumor development in vivo including signature mutations and metastases
Cell Rep Med, 4 (10), 101211
DOI 10.1016/j.xcrm.2023.101211, PubMed 37797615 -
Human APOBEC3B promotes tumor heterogeneity in vivo including signature mutations and metastases
bioRxiv
DOI 10.1101/2023.02.24.529970, PubMed 36865194 -
DNase analysed by a novel competitive assay in patients with complications after ChAdOx1 nCoV-19 vaccination and in normal unvaccinated blood donors
Scand J Immunol, 98 (1), e13274
DOI 10.1111/sji.13274, PubMed 37676118 -
Robust spike-specific CD4+ and CD8+ T cell responses in SARS-CoV-2 vaccinated hematopoietic cell transplantation recipients: a prospective, cohort study
Front Immunol, 14, 1210899
DOI 10.3389/fimmu.2023.1210899, PubMed 37503339 -
A Comparative Analysis of Orthotopic and Subcutaneous Pancreatic Tumour Models: Tumour Microenvironment and Drug Delivery
Cancers (Basel), 15 (22)
DOI 10.3390/cancers15225415, PubMed 38001675 -
Nausea Predicts Bacteremia in Immunocompetent Patients with Pneumococcal Community-Acquired Pneumonia: Secondary Data Analysis from a Prospective Cohort
J Clin Med, 12 (12)
DOI 10.3390/jcm12123924, PubMed 37373619 -
Tracing the adaptive evolution of SARS-CoV-2 during vaccine roll-out in Norway
Virus Evol, 10 (1), vead081
DOI 10.1093/ve/vead081, PubMed 38205440 -
Repurposing Azoles to Resolve Serotogenic Toxicity Associated with Linezolid to Combat Multidrug-Resistant Tuberculosis
ACS Med Chem Lett, 14 (12), 1754-1759
DOI 10.1021/acsmedchemlett.3c00406, PubMed 38116435 -
A multi-country analysis of COVID-19 hospitalizations by vaccination status
Med, 4 (11), 797-812.e2
DOI 10.1016/j.medj.2023.08.005, PubMed 37738979 -
Thrombotic and hemorrhagic complications of COVID-19 in adults hospitalized in high-income countries compared with those in adults hospitalized in low- and middle-income countries in an international registry
Res Pract Thromb Haemost, 7 (5), 102142
DOI 10.1016/j.rpth.2023.102142, PubMed 37601011 -
Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder
Brain Behav Immun, 111, 61-75
DOI 10.1016/j.bbi.2023.03.023, PubMed 37001827 -
The first tigecycline resistant Enterococcus faecium in Norway was related to tigecycline exposure
J Glob Antimicrob Resist, 36, 112-115
DOI 10.1016/j.jgar.2023.12.002, PubMed 38122982 -
Genomic insights into Enterococcus faecium isolates from marine bivalves highlight One Health concerns and healthcare linkages
Microb Genom, 9 (12)
DOI 10.1099/mgen.0.001154, PubMed 38085805 -
A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation
Hepatology, 77 (3), 715-728
DOI 10.1002/hep.32773, PubMed 36056902 -
Reply: The mucosal gut signature in primary sclerosing cholangitis before and after liver transplantation. Is the dysbiosis index really predictive for the recurrence of PSC?
Hepatology, 77 (6), E188-E189
DOI 10.1097/HEP.0000000000000340, PubMed 36815351 -
The Role of Non-Coding RNAs in Epigenetic Dysregulation in Glioblastoma Development
Int J Mol Sci, 24 (22)
DOI 10.3390/ijms242216320, PubMed 38003512 -
Human cytomegalovirus infection perturbs neural progenitor cell fate via the expression of viral microRNAs
J Med Virol, 95 (2), e28574
DOI 10.1002/jmv.28574, PubMed 36772841 -
hGSuite HyperBrowser: A web-based toolkit for hierarchical metadata-informed analysis of genomic tracks
PLoS One, 18 (7), e0286330
DOI 10.1371/journal.pone.0286330, PubMed 37467208 -
Hybrid and SARS-CoV-2-vaccine immunity in kidney transplant recipients
EBioMedicine, 97, 104833
DOI 10.1016/j.ebiom.2023.104833, PubMed 37844534 -
Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19
Int J Epidemiol, 52 (2), 355-376
DOI 10.1093/ije/dyad012, PubMed 36850054 -
TiSA: TimeSeriesAnalysis-a pipeline for the analysis of longitudinal transcriptomics data
NAR Genom Bioinform, 5 (1), lqad020
DOI 10.1093/nargab/lqad020, PubMed 36879899 -
Single-cell m6A mapping in vivo using picoMeRIP-seq
Nat Biotechnol, 42 (4), 591-596
DOI 10.1038/s41587-023-01831-7, PubMed 37349523 -
A loss-of-function mutation in human Oxidation Resistance 1 disrupts the spatial-temporal regulation of histone arginine methylation in neurodevelopment
Genome Biol, 24 (1), 216
DOI 10.1186/s13059-023-03037-1, PubMed 37773136 -
DNA Glycosylases Define the Outcome of Endogenous Base Modifications
Int J Mol Sci, 24 (12)
DOI 10.3390/ijms241210307, PubMed 37373453 -
Genetic Diversity and Expression of Intimin in Escherichia albertii Isolated from Humans, Animals, and Food
Microorganisms, 11 (12)
DOI 10.3390/microorganisms11122843, PubMed 38137987 -
Genome-wide association study of hemolytic uremic syndrome causing Shiga toxin-producing Escherichia coli from Sweden, 1994-2018
Eur J Clin Microbiol Infect Dis, 42 (6), 771-779
DOI 10.1007/s10096-023-04600-1, PubMed 37103716 -
Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants
Cell Rep, 42 (1), 111995
DOI 10.1016/j.celrep.2023.111995, PubMed 36656713 -
Effect of endometrial biopsy method on ribonucleic acid quality and gene expression analysis in patients with leiomyoma
F S Rep, 5 (1), 72-79
DOI 10.1016/j.xfre.2023.11.006, PubMed 38524201 -
A homozygous POLR1A variant causes leukodystrophy and affects protein homeostasis
Brain, 146 (8), 3513-3527
DOI 10.1093/brain/awad086, PubMed 36917474 -
SARS-CoV-2 infection induces long-lived B and T-cell responses up to 15 months post-infection, irrespective of disease severity
J Infect, 87 (4), 346-349
DOI 10.1016/j.jinf.2023.05.023, PubMed 37295510 -
Circulating markers of extracellular matrix remodelling in severe COVID-19 patients
J Intern Med, 294 (6), 784-797
DOI 10.1111/joim.13725, PubMed 37718572 -
COVID-19 patients treated with convalescent plasma
Tidsskr Nor Laegeforen, 143 (11)
DOI 10.4045/tidsskr.22.0577, PubMed 37589359 -
Convalescent plasma from Norwegian blood donors to treat COVID-19
Tidsskr Nor Laegeforen, 143 (11)
DOI 10.4045/tidsskr.22.0180, PubMed 37589362 -
Role of bacteria and microbial metabolites in immune modulation during early life
Scand J Immunol, 99 (2), e13336
DOI 10.1111/sji.13336, PubMed 38441196 -
Hepcidin analysis in pneumonia: Comparison of immunoassay and LC-MS/MS
Ann Clin Biochem, 60 (5), 298-305
DOI 10.1177/00045632231159529, PubMed 36759502 -
Long-Term Nicotinamide Riboside Use Improves Coordination and Eye Movements in Ataxia Telangiectasia
Mov Disord, 39 (2), 360-369
DOI 10.1002/mds.29645, PubMed 37899683 -
Identification of mitophagy-associated proteins profile as potential plasma biomarkers of idiopathic Parkinson's disease
CNS Neurosci Ther, 30 (4), e14532
DOI 10.1111/cns.14532, PubMed 37990436 -
Severely ill COVID-19 patients have altered circulating levels of proteins controlling the epitranscriptome
J Infect, 86 (6), 593-595
DOI 10.1016/j.jinf.2023.03.002, PubMed 36889510 -
The role of PGM1isoform 2 in PGM1-CDG: One step closer to genotype-phenotype correlation?
J Inherit Metab Dis, 46 (2), 159-160
DOI 10.1002/jimd.12601, PubMed 36843136 -
Mitotic chromosome condensation resets chromatin to safeguard transcriptional homeostasis during interphase
Proc Natl Acad Sci U S A, 120 (4), e2210593120
DOI 10.1073/pnas.2210593120, PubMed 36656860 -
Boosted production of antibodies that neutralized different SARS-CoV-2 variants in a COVID-19 convalescent following messenger RNA vaccination - a case study
Int J Infect Dis, 137, 75-78
DOI 10.1016/j.ijid.2023.10.011, PubMed 37852599 -
A fast, low-cost, robust and high-throughput method for viral nucleic acid isolation based on NAxtra magnetic nanoparticles
Sci Rep, 13 (1), 11714
DOI 10.1038/s41598-023-38743-0, PubMed 37474666 -
Guideline for management of septic arthritis in native joints (SANJO)
J Bone Jt Infect, 8 (1), 29-37
DOI 10.5194/jbji-8-29-2023, PubMed 36756304 -
Major adverse cardiovascular events (MACE) in patients with severe COVID-19 registered in the ISARIC WHO clinical characterization protocol: A prospective, multinational, observational study
J Crit Care, 77, 154318
DOI 10.1016/j.jcrc.2023.154318, PubMed 37167775 -
Identification of Mycobacterium abscessus Subspecies by MALDI-TOF Mass Spectrometry and Machine Learning
J Clin Microbiol, 61 (1), e0111022
DOI 10.1128/jcm.01110-22, PubMed 36602341 -
HoCoRT: host contamination removal tool
BMC Bioinformatics, 24 (1), 371
DOI 10.1186/s12859-023-05492-w, PubMed 37784008 -
Design, Synthesis, and Evaluation of Novel Δ2-Thiazolino 2-Pyridone Derivatives That Potentiate Isoniazid Activity in an Isoniazid-Resistant Mycobacterium tuberculosis Mutant
J Med Chem, 66 (16), 11056-11077
DOI 10.1021/acs.jmedchem.3c00358, PubMed 37485869 -
Mitochondria hormesis delays aging and associated diseases in Caenorhabditis elegans impacting on key ferroptosis players
iScience, 26 (4), 106448
DOI 10.1016/j.isci.2023.106448, PubMed 37020951 -
Validation of extracorporeal membrane oxygenation mortality prediction and severity of illness scores in an international COVID-19 cohort
Artif Organs, 47 (9), 1490-1502
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The Molecular Epidemiology of Enterovirus in a Birth Cohort in Nepal
Microbiology Research, 14 (3), 909-917
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Clusters of healthcare-associated SARS-CoV-2 infections in Norwegian hospitals detected by a fully automatic register-based surveillance system
J Hosp Infect, 135, 50-54
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Targeted Central Nervous System Irradiation with Proton Microbeam Induces Mitochondrial Changes in Caenorhabditis elegans
Biology (Basel), 12 (6)
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NAxtra magnetic nanoparticles for low-cost, efficient isolation of mammalian DNA and RNA
Sci Rep, 13 (1), 20836
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Missense mutation Q384K in the APOB gene affecting the large lipid transfer module of apoB reduces the secretion of apoB-100 in the liver without reducing the secretion of apoB-48 in the intestine
J Clin Lipidol, 17 (6), 800-807
DOI 10.1016/j.jacl.2023.08.009, PubMed 37718180 -
Characteristics of Shiga Toxin-Producing Escherichia coli Circulating in Asymptomatic Food Handlers
Toxins (Basel), 15 (11)
DOI 10.3390/toxins15110640, PubMed 37999503 -
Optimization of the Hemolysis Assay for the Assessment of Cytotoxicity
Int J Mol Sci, 24 (3)
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BCKDK deficiency: a treatable neurodevelopmental disease amenable to newborn screening
Brain, 146 (7), 3003-3013
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Mechanisms by which the cystic fibrosis transmembrane conductance regulator may influence SARS-CoV-2 infection and COVID-19 disease severity
FASEB J, 37 (11), e23220
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Survival of Escherichia coli after high-antibiotic stress is dependent on both the pregrown physiological state and incubation conditions
Front Microbiol, 14, 1149978
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The Glioblastoma CircularRNAome
Int J Mol Sci, 24 (19)
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Liver injury in hospitalized patients with COVID-19: An International observational cohort study
PLoS One, 18 (9), e0277859
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Author Correction: Early response evaluation by single cell signaling profiling in acute myeloid leukemia
Nat Commun, 14 (1), 1767
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Author Correction: Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
NPJ Vaccines, 8 (1), 4
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Gut microbiota composition during hospitalization is associated with 60-day mortality after severe COVID-19
Crit Care, 27 (1), 69
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Association of Country Income Level With the Characteristics and Outcomes of Critically Ill Patients Hospitalized With Acute Kidney Injury and COVID-19
Kidney Int Rep, 8 (8), 1514-30 (in press)
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Genetic Characterization of Intimin Gene (eae) in Clinical Shiga Toxin-Producing Escherichia coli Strains from Pediatric Patients in Finland
Toxins (Basel), 15 (12)
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The RNA m6A landscape of mouse oocytes and preimplantation embryos
Nat Struct Mol Biol, 30 (5), 703-709
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Cerebrospinal fluid quinolinic acid is strongly associated with delirium and mortality in hip-fracture patients
J Clin Invest, 133 (2)
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Identifying functional regulatory mutation blocks by integrating genome sequencing and transcriptome data
iScience, 26 (8), 107266
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Characterization of the novel temperate Escherichia coli phage phiStx2k
Arch Virol, 169 (1), 5
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A DnaA‐dependent riboswitch for transcription attenuation of the his operon
mLife, 2 (2), 126-140
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A DnaA-dependent riboswitch for transcription attenuation of the his operon
mLife, 2 (2), 126-140
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Editorial: Novel ligands and receptors in endocrine disorders
Front Cell Dev Biol, 11, 1218271
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Variants in the CETP gene affect levels of HDL cholesterol by reducing the amount, and not the specific lipid transfer activity, of secreted CETP
PLoS One, 18 (12), e0294764
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Immunogenicity and safety of a two-dose regimen with hepatitis E virus vaccine in healthy adults in rural Bangladesh: A randomized, double-blind, controlled, phase 2/pilot trial
Vaccine, 41 (5), 1059-1066
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Novel Quinoline-Based Thiosemicarbazide Derivatives: Synthesis, DFT Calculations, and Investigation of Antitubercular, Antibacterial, and Antifungal Activities
ACS Omega, 8 (43), 40140-40152
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Drug-induced aseptic meningitis
Tidsskr Nor Laegeforen, 143 (1)
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Publications 2022
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Dynamic features of human mitochondrial DNA maintenance and transcription
Front Cell Dev Biol, 10, 984245
DOI 10.3389/fcell.2022.984245, PubMed 36158192 -
abc4pwm: affinity based clustering for position weight matrices in applications of DNA sequence analysis
BMC Bioinformatics, 23 (1), 83
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Ultrafast and Cost-Effective Pathogen Identification and Resistance Gene Detection in a Clinical Setting Using Nanopore Flongle Sequencing
Front Microbiol, 13, 822402
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Characterization of the Upper Respiratory Bacterial Microbiome in Critically Ill COVID-19 Patients
Biomedicines, 10 (5)
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Comparative Genomics of Shiga Toxin-Producing Escherichia coli Strains Isolated from Pediatric Patients with and without Hemolytic Uremic Syndrome from 2000 to 2016 in Finland
Microbiol Spectr, 10 (4), e0066022
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Maternal cytomegalovirus infection and delayed language development in children at 3 years of age-a nested case-control study in a large population-based pregnancy cohort
PLoS One, 17 (12), e0278623
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Symptom-based case definitions for COVID-19: Time and geographical variations for detection at hospital admission among 260,000 patients
Influenza Other Respir Viruses, 16 (6), 1040-1050
DOI 10.1111/irv.13039, PubMed 36825252 -
Proteome Profiling of Mycobacterium tuberculosis Cells Exposed to Nitrosative Stress
ACS Omega, 7 (4), 3470-3482
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Four SARS-CoV-2 vaccine doses or hybrid immunity in patients on immunosuppressive therapies: a Norwegian cohort study
Lancet Rheumatol, 5 (1), e36-e46
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Primary vitrectomy or intravitreal antibiotics followed by early vitrectomy for acute endophthalmitis: A prospective observational study
Acta Ophthalmol, 101 (1), 100-108
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Association of body mass index with COVID-19 related in-hospital death
Clin Nutr, 41 (12), 2924-2926
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Group B Streptococcus colonization at delivery is associated with maternal peripartum infection
PLoS One, 17 (4), e0264309
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Prevention of covid-19 and other acute respiratory infections with cod liver oil supplementation, a low dose vitamin D supplement: quadruple blinded, randomised placebo controlled trial
BMJ, 378, e071245
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Post-acute symptoms 3-15 months after COVID-19 among unvaccinated and vaccinated individuals with a breakthrough infection
Int J Infect Dis, 126, 10-13
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The burden of hospital-attended influenza in Norwegian children
Front Pediatr, 10, 963274
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Transition to PCR diagnosis of cryptosporidiosis and giardiasis in the Norwegian healthcare system: could the increase in reported cases be due to higher sensitivity or a change in the testing algorithm?
Eur J Clin Microbiol Infect Dis, 41 (5), 835-839
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SMUG1 regulates fat homeostasis leading to a fatty liver phenotype in mice
DNA Repair (Amst), 120, 103410
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[Tailored interventions result in better antimicrobial management in Norwegian hospitals]
Tidsskr Nor Laegeforen, 142 (5)
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Factors Affecting Antibiotic Prescription among Hospital Physicians in a Low-Antimicrobial-Resistance Country: A Qualitative Study
Antibiotics (Basel), 11 (1)
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The persistence of anti-Spike antibodies following two SARS-CoV-2 vaccine doses in patients on immunosuppressive therapy compared to healthy controls-a prospective cohort study
BMC Med, 20 (1), 378
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Novel genes and sex differences in COVID-19 severity
Hum Mol Genet, 31 (22), 3789-3806
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Register-based surveillance of COVID-19 in nursing homes
Tidsskr Nor Laegeforen, 142 (8)
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Clinical Outcome of Viral Respiratory Tract Infections in Hospitalized Adults in Norway: High Degree of Inflammation and Need of Emergency Care for Cases With Respiratory Syncytial Virus
Front Med (Lausanne), 9, 866494
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Detailed stratified GWAS analysis for severe COVID-19 in four European populations
Hum Mol Genet, 31 (23), 3945-3966
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Age- and sex-dependent effects of DNA glycosylase Neil3 on amyloid pathology, adult neurogenesis, and memory in a mouse model of Alzheimer's disease
Free Radic Biol Med, 193 (Pt 2), 685-693
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The use of public transport and contraction of SARS-CoV-2 in a large prospective cohort in Norway
BMC Infect Dis, 22 (1), 252
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Cell Cycle-Dependent Transcription: The Cyclin Dependent Kinase Cdk1 Is a Direct Regulator of Basal Transcription Machineries
Int J Mol Sci, 23 (3)
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Case report: A prosthetic valve endocarditis caused by Legionella bozemanae in an immunocompetent patient
Front Med (Lausanne), 9, 1055465
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Affinity maturation of TCR-like antibodies using phage display guided by structural modeling
Protein Eng Des Sel, 35
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Dispersion of SARS-CoV-2 in air surrounding COVID-19-infected individuals with mild symptoms
Indoor Air, 32 (2), e13001
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SARS-CoV-2 in the Air Surrounding Patients during Nebulizer Therapy
Can J Infect Dis Med Microbiol, 2022, 9297974
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An international observational study to assess the impact of the Omicron variant emergence on the clinical epidemiology of COVID-19 in hospitalised patients
Elife, 11
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Omicron Variant Generates a Higher and More Sustained Viral Load in Nasopharynx and Saliva Than the Delta Variant of SARS-CoV-2
Viruses, 14 (11)
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Pseudomonas aeruginosa countrywide outbreak in hospitals linked to pre-moistened non-sterile washcloths, Norway, October 2021 to April 2022
Euro Surveill, 27 (18)
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CXCL16 associates with adverse outcome and cardiac involvement in hospitalized patients with Covid-19
J Infect, 85 (6), 702-769
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Cognitive rehabilitation in post-COVID-19 condition: A study protocol for a randomized controlled trial
Contemp Clin Trials, 122, 106955
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SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells
Cell Rep, 38 (10), 110503
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H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway
Sci Adv, 8 (11), eabf8627
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Risk factors associated with severe disease in respiratory syncytial virus infected children under 5 years of age
Front Pediatr, 10, 1004739
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Corrigendum to 'The burden of respiratory syncytial virus in children under 5 years of age in Norway' [Journal of Infection Volume 84, Issue 2 (2022) Pages 205-215]
J Infect, 86 (4), 420
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Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
J Transl Med, 20 (1), 225
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Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
J Transl Med, 20 (1), 317
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Inflammatory markers calprotectin, NETs, syndecan-1 and neopterin in COVID-19 convalescent blood donors
Scand J Clin Lab Invest, 82 (6), 481-485
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Elevated NETs and Calprotectin Levels after ChAdOx1 nCoV-19 Vaccination Correlate with the Severity of Side Effects
Vaccines (Basel), 10 (8)
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Cri du chat syndrome patients have DNA methylation changes in genes linked to symptoms of the disease
Clin Epigenetics, 14 (1), 128
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DrugVirus.info 2.0: an integrative data portal for broad-spectrum antivirals (BSA) and BSA-containing drug combinations (BCCs)
Nucleic Acids Res, 50 (W1), W272-W275
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ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19
Sci Data, 9 (1), 454
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NEIL3-deficient bone marrow displays decreased hematopoietic capacity and reduced telomere length
Biochem Biophys Rep, 29, 101211
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The Heat Is On: Modeling the Persistence of ESBL-Producing E. coli in Blue Mussels under Meal Preparation
Foods, 12 (1)
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Urea derivatives carrying a thiophenylthiazole moiety: Design, synthesis, and evaluation of antitubercular and InhA inhibitory activities
Drug Dev Res, 83 (6), 1292-1304
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Lactate receptor HCAR1 regulates neurogenesis and microglia activation after neonatal hypoxia-ischemia
Elife, 11
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ALKBH5 regulates somatic cell reprogramming in a phase-specific manner
J Cell Sci, 135 (11)
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Isoniazid Linked to Sulfonate Esters via Hydrazone Functionality: Design, Synthesis, and Evaluation of Antitubercular Activity
Pharmaceuticals (Basel), 15 (10)
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Linking azoles to isoniazid via hydrazone bridge: Synthesis, crystal structure determination, antitubercular evaluation and computational studies
Journal of Molecular Liquids, 354, 118873
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Duodenal inflammation in common variable immunodeficiency has altered transcriptional response to viruses
J Allergy Clin Immunol, 151 (3), 767-777
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EWAS of post-COVID-19 patients shows methylation differences in the immune-response associated gene, IFI44L, three months after COVID-19 infection
Sci Rep, 12 (1), 11478
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Studies on Protein-RNA:DNA Hybrid Interactions by Microscale Thermophoresis (MST)
Methods Mol Biol, 2528, 239-251
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Case Report: Pure Red Cell Aplasia Caused by Refractory Parvovirus B19 Infection After Pancreas Transplantation Alone
Front Med (Lausanne), 9, 849783
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A regulatory network comprising let-7 miRNA and SMUG1 is associated with good prognosis in ER+ breast tumours
Nucleic Acids Res, 50 (18), 10449-10468
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Immobilization of FeFe-hydrogenase on black TiO2 nanotubes as biocathodes for the hydrogen evolution reaction
Electrochemistry Communications, 135, 107221
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Mechanical coupling of supracellular stress amplification and tissue fluidization during exit from quiescence
Proc Natl Acad Sci U S A, 119 (32), e2201328119
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Characterization of a Clostridioides difficile outbreak caused by PCR ribotype 046, associated with increased mortality
Emerg Microbes Infect, 11 (1), 850-859
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Acute severe hepatitis outbreak in children: A perfect storm. What do we know, and what questions remain?
Front Pharmacol, 13, 1062408
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Comparing Screening Outcomes for Digital Breast Tomosynthesis and Digital Mammography by Automated Breast Density in a Randomized Controlled Trial: Results from the To-Be Trial
Radiology, 303 (1), E23
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C. elegans as an Animal Model to Study the Intersection of DNA Repair, Aging and Neurodegeneration
Front Aging, 3, 916118
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Helicobacter pylori resistance to antibiotics before and after treatment: Incidence of eradication failure
PLoS One, 17 (4), e0265322
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DNA Repair Mechanisms are Activated in Circulating Lymphocytes of Hospitalized Covid-19 Patients
J Inflamm Res, 15, 6629-6644
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Mapping of pituitary stress-induced gene regulation connects Nrcam to negative emotions
iScience, 25 (9), 104953
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Malaria prevalence and performance of diagnostic tests among patients hospitalized with acute undifferentiated fever in Zanzibar
Malar J, 21 (1), 54
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Hepcidin predicts 5-year mortality after community-acquired pneumonia
Infect Dis (Lond), 54 (6), 403-409
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Epitranscriptome in Ischemic Cardiovascular Disease: Potential Target for Therapies
Stroke, 53 (6), 2114-2122
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Antiviral Immunoglobulins of Chicken Egg Yolk for Potential Prevention of SARS-CoV-2 Infection
Viruses, 14 (10)
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Clinical characteristics, risk factors and outcomes in patients with severe COVID-19 registered in the International Severe Acute Respiratory and Emerging Infection Consortium WHO clinical characterisation protocol: a prospective, multinational, multicentre, observational study
ERJ Open Res, 8 (1)
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Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, observational study
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Multicentre study on the reproducibility of MALDI-TOF MS for nontuberculous mycobacteria identification
Sci Rep, 12 (1), 1237
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CompAIRR: ultra-fast comparison of adaptive immune receptor repertoires by exact and approximate sequence matching
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MoDLE: high-performance stochastic modeling of DNA loop extrusion interactions
Genome Biol, 23 (1), 247
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Vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccine: A cohort study
J Stroke Cerebrovasc Dis, 32 (1), 106860
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Krill oil protects dopaminergic neurons from age-related degeneration through temporal transcriptome rewiring and suppression of several hallmarks of aging
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Host Transcriptional Signatures Predict Etiology in Community-Acquired Pneumonia: Potential Antibiotic Stewardship Tools
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Treatment of Ductal Carcinoma in situ: A Register-Based Study of Norwegian Women Diagnosed between 1995 and 2018
Breast Care (Basel), 17 (5), 486-494
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Sexually transmitted infections among patients attending a sexual assault centre: a cohort study from Oslo, Norway
BMJ Open, 12 (12), e064934
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Age and product dependent vaccine effectiveness against SARS-CoV-2 infection and hospitalisation among adults in Norway: a national cohort study, July-November 2021
BMC Med, 20 (1), 278
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High vaccine effectiveness against coronavirus disease 2019 (COVID-19) and severe disease among residents and staff of long-term care facilities in Norway, November 2020-June 2021
Antimicrob Steward Healthc Epidemiol, 2 (1), e10
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Characterization of novel small non-coding RNAs and their modifications in bladder cancer using an updated small RNA-seq workflow
Front Mol Biosci, 9, 887686
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TRMT6/61A-dependent base methylation of tRNA-derived fragments regulates gene-silencing activity and the unfolded protein response in bladder cancer
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RNA m6A modifications in mammalian gametogenesis and pregnancy
Reproduction, 165 (1), R1-R8
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ZBTB11 dysfunction: spectrum of brain abnormalities, biochemical signature and cellular consequences
Brain, 145 (7), 2602-2616
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Immunogenicity and safety of a three-dose SARS-CoV-2 vaccination strategy in patients with immune-mediated inflammatory diseases on immunosuppressive therapy
RMD Open, 8 (2)
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Immunogenicity and Safety of Standard and Third-Dose SARS-CoV-2 Vaccination in Patients Receiving Immunosuppressive Therapy
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Breakthrough infections with the omicron and delta variants of SARS-CoV-2 result in similar re-activation of vaccine-induced immunity
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Corticosteroids and superinfections in COVID-19 patients on invasive mechanical ventilation
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Synthesis, characterization, anti-tuberculosis activity and molecular modeling studies of thiourea derivatives bearing aminoguanidine moiety
Journal of Molecular Structure, 1270, 133899
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Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
NPJ Vaccines, 7 (1), 174
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Persistent T-cell exhaustion in relation to prolonged pulmonary pathology and death after severe COVID-19: Results from two Norwegian cohort studies
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High Circulating Levels of the Homeostatic Chemokines CCL19 and CCL21 Predict Mortality and Disease Severity in COVID-19
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Cellsnake: a user-friendly tool for single-cell RNA sequencing analysis
Gigascience, 12
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Surveillance of leishmaniasis cases from 15 European centres, 2014 to 2019: a retrospective analysis
Euro Surveill, 27 (4)
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A point-prevalence study on community and inpatient Clostridioides difficile infections (CDI): results from Combatting Bacterial Resistance in Europe CDI (COMBACTE-CDI), July to November 2018
Euro Surveill, 27 (26)
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Use of an extended KDIGO definition to diagnose acute kidney injury in patients with COVID-19: A multinational study using the ISARIC-WHO clinical characterisation protocol
PLoS Med, 19 (4), e1003969
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Correction: Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits
J Exp Med, 219 (8)
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Clinical characteristics and outcomes in hospitalized adult influenza patients: an observational study from Norway 2014-2018
Infect Dis (Lond), 54 (5), 367-377
DOI 10.1080/23744235.2021.2022196, PubMed 34983302 -
High Prevalence and Persistence of Escherichia coli Strains Producing Shiga Toxin Subtype 2k in Goat Herds
Microbiol Spectr, 10 (4), e0157122
DOI 10.1128/spectrum.01571-22, PubMed 35938860 -
Genomic Characterization of Escherichia coli O8 Strains Producing Shiga Toxin 2l Subtype
Microorganisms, 10 (6)
DOI 10.3390/microorganisms10061245, PubMed 35744763 -
Waves of sumoylation support transcription dynamics during adipocyte differentiation
Nucleic Acids Res, 50 (3), 1351-1369
DOI 10.1093/nar/gkac027, PubMed 35100417 -
Novel mutations in the HADHB gene causing a mild phenotype of mitochondrial trifunctional protein (MTP) deficiency
JIMD Rep, 63 (3), 193-198
DOI 10.1002/jmd2.12276, PubMed 35433169 -
Stability and Feasibility of Dried Blood Spots for Hepatitis E Virus Serology in a Rural Setting
Viruses, 14 (11)
DOI 10.3390/v14112525, PubMed 36423134
Publications 2021
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Non-flipping DNA glycosylase AlkD scans DNA without formation of a stable interrogation complex
Commun Biol, 4 (1), 876
DOI 10.1038/s42003-021-02400-x, PubMed 34267321 -
Novel genomic islands and a new vanD-subtype in the first sporadic VanD-type vancomycin resistant enterococci in Norway
PLoS One, 16 (7), e0255187
DOI 10.1371/journal.pone.0255187, PubMed 34297779 -
Intrinsic Strand-Incision Activity of Human UNG: Implications for Nick Generation in Immunoglobulin Gene Diversification
Front Immunol, 12, 762032
DOI 10.3389/fimmu.2021.762032, PubMed 35003074 -
Molecular Characterization of Two Homozygous Factor VII Variants Associated with Intracranial Bleeding
Thromb Haemost, 121 (12), 1588-1598
DOI 10.1055/a-1450-8568, PubMed 33742435 -
Increased p53 signaling impairs neural differentiation in HUWE1-promoted intellectual disabilities
Cell Rep Med, 2 (4), 100240
DOI 10.1016/j.xcrm.2021.100240, PubMed 33948573 -
AMR-Diag: Neural network based genotype-to-phenotype prediction of resistance towards β-lactams in Escherichia coli and Klebsiella pneumoniae
Comput Struct Biotechnol J, 19, 1896-1906
DOI 10.1016/j.csbj.2021.03.027, PubMed 33897984 -
Whole-Genome Metagenomic Analysis of the Gut Microbiome in HIV-1-Infected Individuals on Antiretroviral Therapy
Front Microbiol, 12, 667718
DOI 10.3389/fmicb.2021.667718, PubMed 34248876 -
Characterization of Clinical Escherichia coli Strains Producing a Novel Shiga Toxin 2 Subtype in Sweden and Denmark
Microorganisms, 9 (11)
DOI 10.3390/microorganisms9112374, PubMed 34835499 -
Genomic Insights Into Clinical Shiga Toxin-Producing Escherichia coli Strains: A 15-Year Period Survey in Jönköping, Sweden
Front Microbiol, 12, 627861
DOI 10.3389/fmicb.2021.627861, PubMed 33613494 -
Ten simple rules for quick and dirty scientific programming
PLoS Comput Biol, 17 (3), e1008549
DOI 10.1371/journal.pcbi.1008549, PubMed 33705383 -
Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial
Ann Intern Med, 174 (9), 1261-1269
DOI 10.7326/M21-0653, PubMed 34251903 -
Molecular Epidemiology and Evolutionary Trajectory of Emerging Echovirus 30, Europe
Emerg Infect Dis, 27 (6), 1616-1626
DOI 10.3201/eid2706.203096, PubMed 34013874 -
The use of eculizumab in Capnocytophaga canimorsus associated thrombotic microangiopathy: a case report
BMC Infect Dis, 21 (1), 137
DOI 10.1186/s12879-021-05789-2, PubMed 33526010 -
Synthesis and Evaluation of Fused Pyrimidines as E. coli Thymidylate Monophosphate Kinase Inhibitors
ChemistrySelect, 6 (45), 12852-12857
DOI 10.1002/slct.202103796 -
Kidney Transplant Recipient Behavior During the Early COVID-19 Pandemic: A National Survey Study in Norway
Kidney Med, 4 (2), 100389
DOI 10.1016/j.xkme.2021.09.006, PubMed 34805967 -
Severe acute respiratory syndrome coronavirus 2 prevalence in 1170 asymptomatic Norwegian conscripts
Health Sci Rep, 4 (1), e233
DOI 10.1002/hsr2.233, PubMed 33490637 -
Outbreak caused by the SARS-CoV-2 Omicron variant in Norway, November to December 2021
Euro Surveill, 26 (50)
DOI 10.2807/1560-7917.ES.2021.26.50.2101147, PubMed 34915975 -
Impact of the Rotavirus Vaccination Program in Norway After Four Years With High Coverage
Pediatr Infect Dis J, 40 (4), 368-374
DOI 10.1097/INF.0000000000003020, PubMed 33399430 -
AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR
Circ Res, 130 (1), 27-44
DOI 10.1161/CIRCRESAHA.120.317976, PubMed 34814703 -
Critical COVID-19 is associated with distinct leukocyte phenotypes and transcriptome patterns
J Intern Med, 290 (3), 677-692
DOI 10.1111/joim.13310, PubMed 34080738 -
Mapping the human genetic architecture of COVID-19
Nature, 600 (7889), 472-477
DOI 10.1038/s41586-021-03767-x, PubMed 34237774 -
Impact of Oxidative DNA Damage and the Role of DNA Glycosylases in Neurological Dysfunction
Int J Mol Sci, 22 (23)
DOI 10.3390/ijms222312924, PubMed 34884729 -
Etiology of viral respiratory tract infections in hospitalized adults, and evidence of the high frequency of prehospitalization antibiotic treatment in Norway
Health Sci Rep, 4 (4), e403
DOI 10.1002/hsr2.403, PubMed 34646942 -
Tick-transmitted co-infections among erythema migrans patients in a general practice setting in Norway: a clinical and laboratory follow-up study
BMC Infect Dis, 21 (1), 1044
DOI 10.1186/s12879-021-06755-8, PubMed 34625049 -
Exploring the role of the multiple sclerosis susceptibility gene CLEC16A in T cells
Scand J Immunol, 94 (1), e13050
DOI 10.1111/sji.13050, PubMed 34643957 -
The Oslo Ischaemia Study: cohort profile
BMJ Open, 11 (10), e049111
DOI 10.1136/bmjopen-2021-049111, PubMed 34645662 -
A novel somatic mutation in GNB2 provides new insights to the pathogenesis of Sturge-Weber syndrome
Hum Mol Genet, 30 (21), 1919-1931
DOI 10.1093/hmg/ddab144, PubMed 34124757 -
Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway
Cell Rep, 37 (13), 110186
DOI 10.1016/j.celrep.2021.110186, PubMed 34965431 -
Genetic diversity of rotavirus strains circulating in Norway before and after the introduction of rotavirus vaccination in children
J Med Virol, 94 (6), 2624-2631
DOI 10.1002/jmv.27484, PubMed 34837228 -
Emergence and dissemination of antimicrobial resistance in Escherichia coli causing bloodstream infections in Norway in 2002-17: a nationwide, longitudinal, microbial population genomic study
Lancet Microbe, 2 (7), e331-e341
DOI 10.1016/S2666-5247(21)00031-8, PubMed 35544167 -
The burden of respiratory syncytial virus in children under 5 years of age in Norway
J Infect, 84 (2), 205-215
DOI 10.1016/j.jinf.2021.12.008, PubMed 34906596 -
Topoisomerase IV tracks behind the replication fork and the SeqA complex during DNA replication in Escherichia coli
Sci Rep, 11 (1), 474
DOI 10.1038/s41598-020-80043-4, PubMed 33436807 -
Cerebrospinal fluid catecholamines in delirium and dementia
Brain Commun, 3 (3), fcab121
DOI 10.1093/braincomms/fcab121, PubMed 34423298 -
NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice
Commun Biol, 4 (1), 1354
DOI 10.1038/s42003-021-02864-x, PubMed 34857879 -
Immune complexes, innate immunity, and NETosis in ChAdOx1 vaccine-induced thrombocytopenia
Eur Heart J, 42 (39), 4064-4072
DOI 10.1093/eurheartj/ehab506, PubMed 34405870 -
Whole-genome characterization of hemolytic uremic syndrome-causing Shiga toxin-producing Escherichia coli in Sweden
Virulence, 12 (1), 1296-1305
DOI 10.1080/21505594.2021.1922010, PubMed 33939581 -
Molecular Characterization of the Enterohemolysin Gene (ehxA) in Clinical Shiga Toxin-Producing Escherichia coli Isolates
Toxins (Basel), 13 (1)
DOI 10.3390/toxins13010071, PubMed 33477906 -
The value of open-source clinical science in pandemic response: lessons from ISARIC
Lancet Infect Dis, 21 (12), 1623-1624
DOI 10.1016/S1473-3099(21)00565-X, PubMed 34619109 -
Ten months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohort
Elife, 10
DOI 10.7554/eLife.70970, PubMed 34812731 -
Evaluation of diagnostic factors used to refer children with constipation for rectal biopsies
Int J Colorectal Dis, 37 (3), 597-605
DOI 10.1007/s00384-021-04069-4, PubMed 34882271 -
A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
Sci Transl Med, 13 (582)
DOI 10.1126/scitranslmed.abb0036, PubMed 33627483 -
N6-methyladenosine (m6A) depletion regulates pluripotency exit by activating signaling pathways in embryonic stem cells
Proc Natl Acad Sci U S A, 118 (51)
DOI 10.1073/pnas.2105192118, PubMed 34921114 -
[Pregnant women should be screened for asymptomatic bacteriuria]
Tidsskr Nor Laegeforen, 141 (11)
DOI 10.4045/tidsskr.21.0379, PubMed 34423934 -
Humoral and cellular immune responses to two and three doses of SARS-CoV-2 vaccines in rituximab-treated patients with rheumatoid arthritis: a prospective, cohort study
Lancet Rheumatol, 4 (3), e177-e187
DOI 10.1016/S2665-9913(21)00394-5, PubMed 34977602 -
[Problematic use of capsaicin patches as pain relief during labour]
Ugeskr Laeger, 183 (19)
PubMed 33998455 -
NEIL3-deficiency increases gut permeability and contributes to a pro-atherogenic metabolic phenotype
Sci Rep, 11 (1), 19749
DOI 10.1038/s41598-021-98820-0, PubMed 34611194 -
The incidence of infectious diseases and viruses other than SARS-CoV-2 amongst hospitalised children in Oslo, Norway during the Covid-19 pandemic 2020-2021
J Clin Virol Plus, 2 (1), 100060
DOI 10.1016/j.jcvp.2021.100060, PubMed 35262033 -
Lyme neuroborreliosis with encephalitis; a systematic literature review and a Scandinavian cohort study
Clin Microbiol Infect, 28 (5), 649-656
DOI 10.1016/j.cmi.2021.11.001, PubMed 34768019 -
Endonuclease V Regulates Atherosclerosis Through C-C Motif Chemokine Ligand 2-Mediated Monocyte Infiltration
J Am Heart Assoc, 10 (14), e020656
DOI 10.1161/JAHA.120.020656, PubMed 34259011 -
DNA repair enzyme NEIL3 enables a stable neural representation of space by shaping transcription in hippocampal neurons
iScience, 24 (12), 103470
DOI 10.1016/j.isci.2021.103470, PubMed 34988395 -
The CRCbiome study: a large prospective cohort study examining the role of lifestyle and the gut microbiome in colorectal cancer screening participants
BMC Cancer, 21 (1), 930
DOI 10.1186/s12885-021-08640-8, PubMed 34407780 -
Humoral immunity to SARS-CoV-2 mRNA vaccination in multiple sclerosis: the relevance of time since last rituximab infusion and first experience from sporadic revaccinations
J Neurol Neurosurg Psychiatry, 94 (1), 19-22
DOI 10.1136/jnnp-2021-327612, PubMed 34670844 -
Neutrophil count predicts clinical outcome in hospitalized COVID-19 patients: Results from the NOR-Solidarity trial
J Intern Med, 291 (2), 241-243
DOI 10.1111/joim.13377, PubMed 34411368 -
Molecular Detection of Borrelia Bacteria in Cerebrospinal Fluid-Optimisation of Pre-Analytical Sample Handling for Increased Analytical Sensitivity
Diagnostics (Basel), 11 (11)
DOI 10.3390/diagnostics11112088, PubMed 34829435 -
Diagnostic performance of a SARS-CoV-2 rapid antigen test in a large, Norwegian cohort
J Clin Virol, 137, 104789
DOI 10.1016/j.jcv.2021.104789, PubMed 33736946 -
[The COVID-19 pandemic – experiences from a microbiology laboratory]
Tidsskr Nor Laegeforen, 141 (18)
DOI 10.4045/tidsskr.21.0643, PubMed 34911278 -
Instability in NAD+ metabolism leads to impaired cardiac mitochondrial function and communication
Elife, 10
DOI 10.7554/eLife.59828, PubMed 34343089 -
Persistent pulmonary pathology after COVID-19 is associated with high viral load, weak antibody response, and high levels of matrix metalloproteinase-9
Sci Rep, 11 (1), 23205
DOI 10.1038/s41598-021-02547-x, PubMed 34853380 -
Rapid SARS-CoV-2 variant monitoring using PCR confirmed by whole genome sequencing in a high-volume diagnostic laboratory
J Clin Virol, 141, 104906
DOI 10.1016/j.jcv.2021.104906, PubMed 34273860 -
Antimicrobial resistance: A challenge awaiting the post-COVID-19 era
Int J Infect Dis, 111, 322-325
DOI 10.1016/j.ijid.2021.09.003, PubMed 34508864 -
Shifts in the Skin Microbiota after UVB Treatment in Adult Atopic Dermatitis
Dermatology, 238 (1), 109-120
DOI 10.1159/000515236, PubMed 33887725 -
Swarm v3: towards tera-scale amplicon clustering
Bioinformatics, 38 (1), 267-269
DOI 10.1093/bioinformatics/btab493, PubMed 34244702 -
Lipid droplets and the transcriptome of Mycobacterium tuberculosis from direct sputa: a literature review
Lipids Health Dis, 20 (1), 129
DOI 10.1186/s12944-021-01550-5, PubMed 34602073 -
Mitochondria in Myelinating Oligodendrocytes: Slow and Out of Breath?
Metabolites, 11 (6)
DOI 10.3390/metabo11060359, PubMed 34198810 -
SARS-CoV-2 in health and care staff in Norway, 2020
Tidsskr Nor Laegeforen, 141 (3)
DOI 10.4045/tidsskr.20.1048, PubMed 33624971 -
Leishmaniasis in Norway
Tidsskr Nor Laegeforen, 141 (3)
DOI 10.4045/tidsskr.19.0171, PubMed 33624958 -
Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality
J Clin Invest, 131 (23)
DOI 10.1172/JCI152386, PubMed 34597274 -
Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality
medRxiv
DOI 10.1101/2021.03.07.21252875, PubMed 33758887 -
The Effect of Antimicrobial Resistance Plasmids Carrying blaCMY-2 on Biofilm Formation by Escherichia coli from the Broiler Production Chain
Microorganisms, 9 (1)
DOI 10.3390/microorganisms9010104, PubMed 33466318 -
Pre-screening and preventive quarantine likely explains the low SARS-CoV-2 prevalence among Norwegian conscripts
Scand J Prim Health Care, 39 (1), 31-34
DOI 10.1080/02813432.2021.1880101, PubMed 33544016 -
[Hepatocellular adenoma as a cause of liver rupture and intrauterine foetal death]
Ugeskr Laeger, 183 (45)
PubMed 34796860 -
Hepcidin and Ferritin Predict Microbial Etiology in Community-Acquired Pneumonia
Open Forum Infect Dis, 8 (4), ofab082
DOI 10.1093/ofid/ofab082, PubMed 33880390 -
Multicenter Evaluation of Rapid BACpro® II for the Accurate Identification of Microorganisms Directly from Blood Cultures Using MALDI-TOF MS
Diagnostics (Basel), 11 (12)
DOI 10.3390/diagnostics11122251, PubMed 34943488 -
Intestinal-epithelial LSD1 controls goblet cell maturation and effector responses required for gut immunity to bacterial and helminth infection
PLoS Pathog, 17 (3), e1009476
DOI 10.1371/journal.ppat.1009476, PubMed 33788902 -
A man in his seventies with pleural effusion, knee pain and dysarthria following open heart surgery
Tidsskr Nor Laegeforen, 141 (18)
DOI 10.4045/tidsskr.21.0163, PubMed 34911264 -
Synthesis and antimicrobial activities of chitosan/polypropylene carbonate-based nanoparticles
RSC Adv, 11 (17), 10121-10129
DOI 10.1039/d0ra09257f, PubMed 35423476 -
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
Atherosclerosis, 324, 123-132
DOI 10.1016/j.atherosclerosis.2021.02.023, PubMed 33714552 -
Prevalence of genotypic antimicrobial resistance in clinical Shiga toxin-producing Escherichia coli in Norway, 2018 to 2020
J Med Microbiol, 70 (12)
DOI 10.1099/jmm.0.001454, PubMed 34870582 -
Characterization of Shiga Toxin 2a Encoding Bacteriophages Isolated From High-Virulent O145:H25 Shiga Toxin-Producing Escherichia coli
Front Microbiol, 12, 728116
DOI 10.3389/fmicb.2021.728116, PubMed 34566932 -
Screening bioactive food compounds in honey bees suggests curcumin blocks alcohol-induced damage to longevity and DNA methylation
Sci Rep, 11 (1), 19156
DOI 10.1038/s41598-021-98614-4, PubMed 34580381 -
Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation
Nucleic Acids Res, 49 (3), 1470-1484
DOI 10.1093/nar/gkaa1289, PubMed 33444446 -
Human telomerase is directly regulated by non-telomeric TRF2-G-quadruplex interaction
Cell Rep, 35 (7), 109154
DOI 10.1016/j.celrep.2021.109154, PubMed 34010660 -
Diversity of Rotavirus Strains in Children; Results From a Community-Based Study in Nepal
Front Med (Lausanne), 8, 712326
DOI 10.3389/fmed.2021.712326, PubMed 34660624 -
What is the recovery rate and risk of long-term consequences following a diagnosis of COVID-19? A harmonised, global longitudinal observational study protocol
BMJ Open, 11 (3), e043887
DOI 10.1136/bmjopen-2020-043887, PubMed 33692181 -
Risk ranking and source attribution of food- and waterborne pathogens for surveillance purposes. Opinion of the Panel on Biological Hazards of the Norwegian Scientific Committee for Food and Environment
VKM Report, 2021 (10), 1-252
PublikaID 392 -
CdgL is a degenerate nucleotide cyclase domain protein affecting flagellin synthesis and motility in Bacillus thuringiensis
Res Microbiol, 172 (4-5), 103850
DOI 10.1016/j.resmic.2021.103850, PubMed 34082027 -
Sepsis treatment options identified by 10-year study of microbial isolates and antibiotic susceptibility in a level-four neonatal intensive care unit
Acta Paediatr, 111 (3), 519-526
DOI 10.1111/apa.16189, PubMed 34787905 -
Self-reported Memory Problems 8 Months After COVID-19 Infection
JAMA Netw Open, 4 (7), e2118717
DOI 10.1001/jamanetworkopen.2021.18717, PubMed 34323987 -
Persisting symptoms three to eight months after non-hospitalized COVID-19, a prospective cohort study
PLoS One, 16 (8), e0256142
DOI 10.1371/journal.pone.0256142, PubMed 34437579 -
Alleviation of C⋅C Mismatches in DNA by the Escherichia coli Fpg Protein
Front Microbiol, 12, 608839
DOI 10.3389/fmicb.2021.608839, PubMed 34276575 -
Increased inflammatory markers reflecting fibrogenesis are independently associated with cardiac involvement in hospitalized COVID-19 patients
J Infect, 82 (5), 186-230
DOI 10.1016/j.jinf.2021.01.017, PubMed 33516748 -
Correction: Characteristics of pulmonary multidrug-resistant tuberculosis patients in Tigray Region, Ethiopia: A cross-sectional study
PLoS One, 16 (10), e0258457
DOI 10.1371/journal.pone.0258457, PubMed 34614019 -
Whole Genome Sequencing of Drug Resistant and Drug Susceptible Mycobacterium tuberculosis Isolates From Tigray Region, Ethiopia
Front Microbiol, 12, 743198
DOI 10.3389/fmicb.2021.743198, PubMed 34938276 -
In situ cofactor regeneration enables selective CO2 reduction in a stable and efficient enzymatic photoelectrochemical cell
Appl. Catal. B-Environ., 296, 120349
DOI 10.1016/j.apcatb.2021.120349 -
High performance and toxicity assessment of Ta3N5 nanotubes for photoelectrochemical water splitting
Catal. Today, 361, 57-62
DOI 10.1016/j.cattod.2019.12.031 -
Genomic Characteristics of Stx2e-Producing Escherichia coli Strains Derived from Humans, Animals, and Meats
Pathogens, 10 (12)
DOI 10.3390/pathogens10121551, PubMed 34959506 -
ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing
Nat Cell Biol, 23 (7), 684-691
DOI 10.1038/s41556-021-00709-7, PubMed 34253897 -
Blood neurofilament light concentration at admittance: a potential prognostic marker in COVID-19
J Neurol, 268 (10), 3574-3583
DOI 10.1007/s00415-021-10517-6, PubMed 33743046 -
Interleukin-6 in Critical Coronavirus Disease 2019, a Driver of Lung Inflammation of Systemic Origin?
Crit Care Explor, 3 (10), e0542
DOI 10.1097/CCE.0000000000000542, PubMed 34604785
Publications 2020
-
Antibiotic resistance: turning evolutionary principles into clinical reality
FEMS Microbiol Rev, 44 (2), 171-188
DOI 10.1093/femsre/fuaa001, PubMed 31981358 -
Review on the Alteration of Gut Microbiota: The Role of HIV Infection and Old Age
AIDS Res Hum Retroviruses, 36 (7), 556-565
DOI 10.1089/AID.2019.0282, PubMed 32323556 -
Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the α-D-phosphohexomutase superfamily
Sci Rep, 10 (1), 5656
DOI 10.1038/s41598-020-62548-0, PubMed 32221390 -
Parvovirus B19 DNAemia in pregnant women in relation to perinatal death: A nested case-control study within a large population-based pregnancy cohort
Acta Obstet Gynecol Scand, 99 (7), 856-864
DOI 10.1111/aogs.13801, PubMed 31925774 -
[Asylum seekers’ health and use of health services in Norway]
Tidsskr Nor Laegeforen, 140 (4)
DOI 10.4045/tidsskr.19.0470, PubMed 32192269 -
Nobel Prize for discovering how cells adapt to changing oxygen levels
Tidsskr. Nor. Laegeforen., 140 (1), 8 -
Antibiotic-induced DNA damage results in a controlled loss of pH homeostasis and genome instability
Sci Rep, 10 (1), 19422
DOI 10.1038/s41598-020-76426-2, PubMed 33173044 -
[Antibiotic use in hospitals in cases of COVID-19]
Tidsskr Nor Laegeforen, 140 (11)
DOI 10.4045/tidsskr.20.0443, PubMed 32815355 -
Hospital physicians' experiences with procalcitonin - implications for antimicrobial stewardship; a qualitative study
BMC Infect Dis, 20 (1), 515
DOI 10.1186/s12879-020-05246-6, PubMed 32677903 -
HMST-Seq-Analyzer: A new python tool for differential methylation and hydroxymethylation analysis in various DNA methylation sequencing data
Comput Struct Biotechnol J, 18, 2877-2889
DOI 10.1016/j.csbj.2020.09.038, PubMed 33163148 -
Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing
Mech Ageing Dev, 186, 111208
DOI 10.1016/j.mad.2020.111208, PubMed 31953124 -
The Escherichia coli alkA Gene Is Activated to Alleviate Mutagenesis by an Oxidized Deoxynucleoside
Front Microbiol, 11, 263
DOI 10.3389/fmicb.2020.00263, PubMed 32158436 -
A European multicentre evaluation of detection and typing methods for human enteroviruses and parechoviruses using RNA transcripts
J Med Virol, 92 (8), 1065-1074
DOI 10.1002/jmv.25659, PubMed 31883139 -
Factors increasing the risk of inappropriate vancomycin therapy in ICU patients: A prospective observational study
Acta Anaesthesiol Scand, 64 (9), 1295-1304
DOI 10.1111/aas.13658, PubMed 32578201 -
Elevated markers of gut leakage and inflammasome activation in COVID-19 patients with cardiac involvement
J Intern Med, 289 (4), 523-531
DOI 10.1111/joim.13178, PubMed 32976665 -
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients
Proc Natl Acad Sci U S A, 117 (40), 25018-25025
DOI 10.1073/pnas.2010540117, PubMed 32943538 -
Molecular characteristics of eae-positive clinical Shiga toxin-producing Escherichia coli in Sweden
Emerg Microbes Infect, 9 (1), 2562-2570
DOI 10.1080/22221751.2020.1850182, PubMed 33179570 -
Observed reduction in the diagnosis of acute lymphoblastic leukaemia in children during the COVID-19 pandemic
Acta Paediatr, 110 (2), 596-597
DOI 10.1111/apa.15576, PubMed 32959407 -
Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19
Sci Rep, 10 (1), 21697
DOI 10.1038/s41598-020-78710-7, PubMed 33303843 -
NucBreak: location of structural errors in a genome assembly by using paired-end Illumina reads
BMC Bioinformatics, 21 (1), 66
DOI 10.1186/s12859-020-3414-0, PubMed 32085722 -
[Perinatal care of the extremely preterm infants]
Ugeskr Laeger, 182 (14A)
PubMed 32285789 -
Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma
Nucleic Acids Res, 48 (8), 4463-4479
DOI 10.1093/nar/gkaa115, PubMed 32083667 -
Invasive pulmonary aspergillosis treatment duration in haematology patients in Europe: An EFISG, IDWP-EBMT, EORTC-IDG and SEIFEM survey
Mycoses, 63 (5), 420-429
DOI 10.1111/myc.13056, PubMed 32009262 -
Modifications and interactions at the R-loop
DNA Repair (Amst), 96, 102958
DOI 10.1016/j.dnarep.2020.102958, PubMed 32961406 -
Genetic diversity and drug resistance pattern of Mycobacterium tuberculosis strains isolated from pulmonary tuberculosis patients in the Benishangul Gumuz region and its surroundings, Northwest Ethiopia
PLoS One, 15 (4), e0231320
DOI 10.1371/journal.pone.0231320, PubMed 32267877 -
Early fulminant BK polyomavirus-associated nephropathy in two kidney transplant patients with low neutralizing antibody titers receiving allografts from the same donor
Virol J, 17 (1), 5
DOI 10.1186/s12985-019-1275-9, PubMed 31924245 -
Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction
JACC Basic Transl Sci, 5 (12), 1210-1224
DOI 10.1016/j.jacbts.2020.09.013, PubMed 33426377 -
Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency
Front Immunol, 11, 574500
DOI 10.3389/fimmu.2020.574500, PubMed 33042155 -
Analysis of epigenetic aging in vivo and in vitro: Factors controlling the speed and direction
Exp Biol Med (Maywood), 245 (17), 1543-1551
DOI 10.1177/1535370220947015, PubMed 32762265 -
Helicobacter pylori in early childhood and asthma in adolescence
BMC Res Notes, 13 (1), 79
DOI 10.1186/s13104-020-04941-6, PubMed 32070394 -
Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease
iScience, 23 (10), 101556
DOI 10.1016/j.isci.2020.101556, PubMed 33083725 -
Peptides containing the PCNA interacting motif APIM bind to the β-clamp and inhibit bacterial growth and mutagenesis
Nucleic Acids Res, 48 (10), 5540-5554
DOI 10.1093/nar/gkaa278, PubMed 32347931 -
Clinical characterization of Helicobacter pylori infected patients 15 years after unsuccessful eradication
PLoS One, 15 (9), e0238944
DOI 10.1371/journal.pone.0238944, PubMed 32966303 -
An intact C-terminal end of albumin is required for its long half-life in humans
Commun Biol, 3 (1), 181
DOI 10.1038/s42003-020-0903-7, PubMed 32313072 -
Author Correction: Structural Features of a Bacteroidetes-Affiliated Cellulase Linked with a Polysaccharide Utilization Locus
Sci Rep, 10 (1), 6287
DOI 10.1038/s41598-020-62786-2, PubMed 32269252 -
Field performance of HBsAg rapid diagnostic tests in rural Ethiopia
J Virol Methods, 289, 114061
DOI 10.1016/j.jviromet.2020.114061, PubMed 33388369 -
Sudden emergence of a Neisseria gonorrhoeae clade with reduced susceptibility to extended-spectrum cephalosporins, Norway
Microb Genom, 6 (12)
DOI 10.1099/mgen.0.000480, PubMed 33200978 -
PML Regulates the Epidermal Differentiation Complex and Skin Morphogenesis during Mouse Embryogenesis
Genes (Basel), 11 (10)
DOI 10.3390/genes11101130, PubMed 32992884 -
N6-methyladenosine in RNA of atherosclerotic plaques: An epitranscriptomic signature of human carotid atherosclerosis
Biochem Biophys Res Commun, 533 (4), 631-637
DOI 10.1016/j.bbrc.2020.09.057, PubMed 33004177 -
Effects of antimicrobials on Shiga toxin production in high-virulent Shiga toxin-producing Escherichia coli
Microb Pathog, 152, 104636
DOI 10.1016/j.micpath.2020.104636, PubMed 33242644 -
Parp3 promotes astrocytic differentiation through a tight regulation of Nox4-induced ROS and mTorc2 activation
Cell Death Dis, 11 (11), 954
DOI 10.1038/s41419-020-03167-5, PubMed 33159039 -
IGAP-integrative genome analysis pipeline reveals new gene regulatory model associated with nonspecific TF-DNA binding affinity
Comput Struct Biotechnol J, 18, 1270-1286
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KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes
Nat Cell Biol, 22 (4), 380-388
DOI 10.1038/s41556-020-0494-z, PubMed 32231309 -
The DIRAC code for relativistic molecular calculations
J Chem Phys, 152 (20), 204104
DOI 10.1063/5.0004844, PubMed 32486677 -
DNA glycosylase Neil2 contributes to genomic responses in the spleen during clinical prion disease
Free Radic Biol Med, 152, 348-354
DOI 10.1016/j.freeradbiomed.2020.03.030, PubMed 32259578 -
Second-Tier Next Generation Sequencing Integrated in Nationwide Newborn Screening Provides Rapid Molecular Diagnostics of Severe Combined Immunodeficiency
Front Immunol, 11, 1417
DOI 10.3389/fimmu.2020.01417, PubMed 32754152 -
Rapid identification of pathogens, antibiotic resistance genes and plasmids in blood cultures by nanopore sequencing
Sci Rep, 10 (1), 7622
DOI 10.1038/s41598-020-64616-x, PubMed 32376847 -
Status of COVID-19 vaccine development
Tidsskr Nor Laegeforen, 140 (13)
DOI 10.4045/tidsskr.20.0676, PubMed 32998488 -
Evaluation of eleven rapid tests for detection of antibodies against SARS-CoV-2
Clin Chem Lab Med, 58 (9), 1595-1600
DOI 10.1515/cclm-2020-0628, PubMed 32598303 -
Elevated plasma sTIM-3 levels in patients with severe COVID-19
J Allergy Clin Immunol, 147 (1), 92-98
DOI 10.1016/j.jaci.2020.09.007, PubMed 32971109 -
[Norway’s microbiological preparedness under threat]
Tidsskr Nor Laegeforen, 140 (11)
DOI 10.4045/tidsskr.20.0451, PubMed 32815358 -
Structural adaptation of vertebrate endonuclease G for 5-hydroxymethylcytosine recognition and function
Nucleic Acids Res, 48 (7), 3962-3974
DOI 10.1093/nar/gkaa117, PubMed 32095813 -
Characteristics of pulmonary multidrug-resistant tuberculosis patients in Tigray Region, Ethiopia: A cross-sectional study
PLoS One, 15 (8), e0236362
DOI 10.1371/journal.pone.0236362, PubMed 32797053 -
Frequency and patterns of first- and second-line drug resistance-conferring mutations in Mycobacterium tuberculosis isolated from pulmonary tuberculosis patients in a cross-sectional study in Tigray Region, Ethiopia
J Glob Antimicrob Resist, 24, 6-13
DOI 10.1016/j.jgar.2020.11.017, PubMed 33279682 -
Late onset periprosthetic infection of the hip caused by the fish pathogen Lactococcus garvieae in a patient not associated with fish exposure
J Bone Jt Infect, 5 (3), 106-109
DOI 10.7150/jbji.43655, PubMed 32566447 -
OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
Cell Rep, 30 (12), 4165-4178.e7
DOI 10.1016/j.celrep.2020.02.063, PubMed 32209476 -
Genetic diversity of the intimin gene (eae) in non-O157 Shiga toxin-producing Escherichia coli strains in China
Sci Rep, 10 (1), 3275
DOI 10.1038/s41598-020-60225-w, PubMed 32094410 -
The 3D genomic landscape of differential response to EGFR/HER2 inhibition in endocrine-resistant breast cancer cells
Biochim Biophys Acta Gene Regul Mech, 1863 (11), 194631
DOI 10.1016/j.bbagrm.2020.194631, PubMed 32956836 -
Lineage-Specific Proteomic Signatures in the Mycobacterium tuberculosis Complex Reveal Differential Abundance of Proteins Involved in Virulence, DNA Repair, CRISPR-Cas, Bioenergetics and Lipid Metabolism
Front Microbiol, 11, 550760
DOI 10.3389/fmicb.2020.550760, PubMed 33072011 -
Hemolytic uremic syndrome caused by Shiga toxin-producing Escherichia coli in children: incidence, risk factors, and clinical outcome
Pediatr Nephrol, 35 (9), 1749-1759
DOI 10.1007/s00467-020-04560-0, PubMed 32323005 -
LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium
Sci Adv, 6 (37)
DOI 10.1126/sciadv.abc0367, PubMed 32917713 -
Protozoan infections are under-recognized in Swedish patients with gastrointestinal symptoms
Eur J Clin Microbiol Infect Dis, 39 (11), 2153-2160
DOI 10.1007/s10096-020-03974-w, PubMed 32638222
Publications 2019
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N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells
Nat Genet, 52 (1), 48-55
DOI 10.1038/s41588-019-0549-x, PubMed 31844323 -
Publisher Correction: Breaking the speed limit with multimode fast scanning of DNA by Endonuclease V
Nat Commun, 10 (1), 1991
DOI 10.1038/s41467-019-10070-x, PubMed 31024006 -
Additive manufacturing of laminar flow cells for single-molecule experiments
Sci Rep, 9 (1), 16784
DOI 10.1038/s41598-019-53151-z, PubMed 31727950 -
Excision of uracil from DNA by hSMUG1 includes strand incision and processing
Nucleic Acids Res, 47 (2), 779-793
DOI 10.1093/nar/gky1184, PubMed 30496516 -
The SH3 domains of the protein kinases ITK and LCK compete for adjacent sites on T cell-specific adapter protein
J Biol Chem, 294 (42), 15480-15494
DOI 10.1074/jbc.RA119.008318, PubMed 31484725 -
Experiences from multiplex PCR diagnostics of faeces in hospitalised patients: clinical significance of Enteropathogenic Escherichia coli (EPEC) and culture negative campylobacter
BMC Infect Dis, 19 (1), 630
DOI 10.1186/s12879-019-4271-1, PubMed 31315581 -
Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform
PLoS One, 14 (11), e0225081
DOI 10.1371/journal.pone.0225081, PubMed 31703097 -
A man in his 80s with arthritis and persistent fever
Tidsskr Nor Laegeforen, 139 (13)
DOI 10.4045/tidsskr.18.0546, PubMed 31556531 -
Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial
BMJ, 367, l5654
DOI 10.1136/bmj.l5654, PubMed 31619437 -
Common Nodes of Virus-Host Interaction Revealed Through an Integrated Network Analysis
Front Immunol, 10, 2186
DOI 10.3389/fimmu.2019.02186, PubMed 31636628 -
Ten years of external quality assessment (EQA) of Neisseria gonorrhoeae antimicrobial susceptibility testing in Europe elucidate high reliability of data
BMC Infect Dis, 19 (1), 281
DOI 10.1186/s12879-019-3900-z, PubMed 30909883 -
Quantifying the transmission dynamics of MRSA in the community and healthcare settings in a low-prevalence country
Proc Natl Acad Sci U S A, 116 (29), 14599-14605
DOI 10.1073/pnas.1900959116, PubMed 31262808 -
Going low to reach high: Small-scale ChIP-seq maps new terrain
Wiley Interdiscip Rev Syst Biol Med, 12 (1), e1465
DOI 10.1002/wsbm.1465, PubMed 31478357 -
Effect of hormone replacement therapy on atherogenic lipid profile in postmenopausal women
Thromb Res, 184, 1-7
DOI 10.1016/j.thromres.2019.10.005, PubMed 31677448 -
The impact of age on risk assessment, therapeutic practice and outcome in candidemia
Infect Dis (Lond), 51 (6), 425-434
DOI 10.1080/23744235.2019.1595709, PubMed 31010380 -
Expanding the activity spectrum of antiviral agents
Drug Discov Today, 24 (5), 1224-1228
DOI 10.1016/j.drudis.2019.04.006, PubMed 30980905 -
"Too much guts and not enough brains": (epi)genetic mechanisms and future therapies of Hirschsprung disease - a review
Clin Epigenetics, 11 (1), 135
DOI 10.1186/s13148-019-0718-x, PubMed 31519213 -
Centralspindlin Recruits ALIX to the Midbody during Cytokinetic Abscission in Drosophila via a Mechanism Analogous to Virus Budding
Curr Biol, 29 (20), 3538-3548.e7
DOI 10.1016/j.cub.2019.09.025, PubMed 31607533 -
Towards dual inhibitors of the MET kinase and WNT signaling pathway; design, synthesis and biological evaluation
RSC Adv, 9 (63), 37092-37100
DOI 10.1039/c9ra08954c, PubMed 35539091 -
Selection of antibiotics-important change in sample response from the microbiologist
Tidsskr. Nor. Laegeforen., 139 (12), 1132-1133 -
PML Bodies in Mitosis
Cells, 8 (8)
DOI 10.3390/cells8080893, PubMed 31416160 -
Structural and Thermodynamic Signatures of Ligand Binding to the Enigmatic Chitinase D of Serratia proteamaculans
J Phys Chem B, 123 (10), 2270-2279
DOI 10.1021/acs.jpcb.8b11448, PubMed 30789732 -
Immunity to varicella zoster virus among pregnant women in the Norwegian Mother and Child Cohort Study
PLoS One, 14 (8), e0221084
DOI 10.1371/journal.pone.0221084, PubMed 31408478 -
Occurrence of and risk factors for extended-spectrum cephalosporin-resistant Enterobacteriaceae determined by sampling of all Norwegian broiler flocks during a six month period
PLoS One, 14 (9), e0223074
DOI 10.1371/journal.pone.0223074, PubMed 31557254 -
Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression
Nat Commun, 10 (1), 5460
DOI 10.1038/s41467-019-13394-w, PubMed 31784530 -
[Neurological symptoms in pregnant women without any diagnosed neurological disease]
Ugeskr Laeger, 181 (14)
PubMed 30950370 -
Desumoylation of RNA polymerase III lies at the core of the Sumo stress response in yeast
J Biol Chem, 294 (49), 18784-18795
DOI 10.1074/jbc.RA119.009721, PubMed 31676685 -
A woman in her fifties with trismus and muscle spasms
Tidsskr Nor Laegeforen, 139 (16)
DOI 10.4045/tidsskr.18.0987, PubMed 31686491 -
Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia
Circ Arrhythm Electrophysiol, 12 (4), e007045
DOI 10.1161/CIRCEP.118.007045, PubMed 30943765 -
HIV-1 molecular transmission clusters in nine European countries and Canada: association with demographic and clinical factors
BMC Med, 17 (1), 4
DOI 10.1186/s12916-018-1241-1, PubMed 30616632 -
ALKBH overexpression in head and neck cancer: potential target for novel anticancer therapy
Sci Rep, 9 (1), 13249
DOI 10.1038/s41598-019-49550-x, PubMed 31519943 -
5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to Replication
Sci Rep, 9 (1), 11065
DOI 10.1038/s41598-019-47528-3, PubMed 31363131 -
To what extent can clinical characteristics be used to distinguish encephalitis from encephalopathy of other causes? Results from a prospective observational study
BMC Infect Dis, 19 (1), 80
DOI 10.1186/s12879-018-3570-2, PubMed 30669985 -
Encephalitis and aseptic meningitis: short-term and long-term outcome, quality of life and neuropsychological functioning
Sci Rep, 9 (1), 16158
DOI 10.1038/s41598-019-52570-2, PubMed 31695095 -
Biallelic POLR3A variants confirmed as a frequent cause of hereditary ataxia and spastic paraparesis
Brain, 142 (4), e12
DOI 10.1093/brain/awz041, PubMed 30847471 -
Diverse functions of DNA glycosylases processing oxidative base lesions in brain
DNA Repair (Amst), 81, 102665
DOI 10.1016/j.dnarep.2019.102665, PubMed 31327582 -
Imported visceral leishmaniasis and immunosuppression in seven Norwegian patients
Trop Dis Travel Med Vaccines, 5, 16
DOI 10.1186/s40794-019-0092-x, PubMed 31463070 -
The recent emergence of a highly related virulent Clostridium difficile clade with unique characteristics
Clin Microbiol Infect, 26 (4), 492-498
DOI 10.1016/j.cmi.2019.09.004, PubMed 31525517 -
Introducing RpsA Point Mutations Δ438A and D123A into the Chromosome of Mycobacterium tuberculosis Confirms Their Role in Causing Resistance to Pyrazinamide
Antimicrob Agents Chemother, 63 (6)
DOI 10.1128/AAC.02681-18, PubMed 30858213 -
Whole genome sequencing of Salmonella Chester reveals geographically distinct clusters, Norway, 2000 to 2016
Euro Surveill, 24 (4)
DOI 10.2807/1560-7917.ES.2019.24.4.1800186, PubMed 30696528 -
Age-Related Oxidative Changes in Primary Porcine Fibroblasts Expressing Mutated Huntingtin
Neurodegener Dis, 19 (1), 22-34
DOI 10.1159/000500091, PubMed 31167196 -
Lysosomal acid lipase does not have a propeptide and should not be considered being a proprotein
Proteins, 88 (3), 440-448
DOI 10.1002/prot.25821, PubMed 31587363 -
Epigenetic age is a cell-intrinsic property in transplanted human hematopoietic cells
Aging Cell, 18 (2), e12897
DOI 10.1111/acel.12897, PubMed 30712319 -
Characterization of the mechanisms by which missense mutations in the lysosomal acid lipase gene disrupt enzymatic activity
Hum Mol Genet, 28 (18), 3043-3052
DOI 10.1093/hmg/ddz114, PubMed 31131398 -
High performance and toxicity assessment of Ta3N5 nanotubes for photoelectrochemical water splitting
Catalysis Today, 0, 1-6 (in press)
DOI 10.1016/j.cattod.2019.12.031, PublikaID 337 -
Low Cellular NAD+ Compromises Lipopolysaccharide-Induced Inflammatory Responses via Inhibiting TLR4 Signal Transduction in Human Monocytes
J Immunol, 203 (6), 1598-1608
DOI 10.4049/jimmunol.1801382, PubMed 31427442 -
Neuromodulatory Effect of NLRP3 and ASC in Neonatal Hypoxic Ischemic Encephalopathy
Neonatology, 115 (4), 355-362
DOI 10.1159/000497200, PubMed 30909283 -
Histone Methylations Define Neural Stem/Progenitor Cell Subtypes in the Mouse Subventricular Zone
Mol Neurobiol, 57 (2), 997-1008
DOI 10.1007/s12035-019-01777-5, PubMed 31654318
Publications 2018
-
Breaking the speed limit with multimode fast scanning of DNA by Endonuclease V
Nat Commun, 9 (1), 5381
DOI 10.1038/s41467-018-07797-4, PubMed 30568191 -
Excision of the doubly methylated base N4,5-dimethylcytosine from DNA by Escherichia coli Nei and Fpg proteins
Philos Trans R Soc Lond B Biol Sci, 373 (1748)
DOI 10.1098/rstb.2017.0337, PubMed 29685966 -
A genomic view of experimental intraspecies and interspecies transformation of a rifampicin-resistance allele into Neisseria meningitidis
Microb Genom, 4 (11)
DOI 10.1099/mgen.0.000222, PubMed 30251949 -
Increased nuclear DNA damage precedes mitochondrial dysfunction in peripheral blood mononuclear cells from Huntington's disease patients
Sci Rep, 8 (1), 9817
DOI 10.1038/s41598-018-27985-y, PubMed 29959348 -
A transgenic minipig model of Huntington's disease shows early signs of behavioral and molecular pathologies
Dis Model Mech, 11 (10)
DOI 10.1242/dmm.035949, PubMed 30254085 -
Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity
Mol Cancer, 17 (1), 171
DOI 10.1186/s12943-018-0918-6, PubMed 30526604 -
Maternal and congenital cytomegalovirus infections in a population-based pregnancy cohort study
APMIS, 126 (12), 899-906
DOI 10.1111/apm.12899, PubMed 30378168 -
How low can you go? Pushing the limits of low-input ChIP-seq
Brief Funct Genomics, 17 (2), 89-95
DOI 10.1093/bfgp/elx037, PubMed 29087438 -
The Role of Mitochondrial Dysfunction in the Progression of Alzheimer's Disease
Curr Med Chem, 25 (40), 5578-5587
DOI 10.2174/0929867324666170616110111, PubMed 28618998 -
[Diagnostics and treatment of iron deficiency in pregnancy]
Ugeskr Laeger, 180 (41)
PubMed 30327079 -
Normal development of mice lacking PAXX, the paralogue of XRCC4 and XLF
FEBS Open Bio, 8 (3), 426-434
DOI 10.1002/2211-5463.12381, PubMed 29511619 -
STIM1 R304W causes muscle degeneration and impaired platelet activation in mice
Cell Calcium, 76, 87-100
DOI 10.1016/j.ceca.2018.10.001, PubMed 30390422 -
Corrigendum: Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
Nucleic Acids Res, 46 (22), 12188-12189
DOI 10.1093/nar/gky1102, PubMed 30395271 -
Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
Nucleic Acids Res, 46 (22), 11698-11711
DOI 10.1093/nar/gky846, PubMed 30247619 -
Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction
Sci Rep, 8 (1), 6725
DOI 10.1038/s41598-018-25168-3, PubMed 29712976 -
Positioning Europe for the EPITRANSCRIPTOMICS challenge
RNA Biol, 15 (6), 829-831
DOI 10.1080/15476286.2018.1460996, PubMed 29671387 -
Expression of nucleotide excision repair in Alzheimer's disease is higher in brain tissue than in blood
Neurosci Lett, 672, 53-58
DOI 10.1016/j.neulet.2018.02.043, PubMed 29474873 -
Transfer of a bla CTX-M-1-carrying plasmid between different Escherichia coli strains within the human gut explored by whole genome sequencing analyses
Sci Rep, 8 (1), 280
DOI 10.1038/s41598-017-18659-2, PubMed 29321570 -
Ythdf2-mediated m6A mRNA clearance modulates neural development in mice
Genome Biol, 19 (1), 69
DOI 10.1186/s13059-018-1436-y, PubMed 29855337 -
Influence of acute promyelocytic leukemia therapeutic drugs on nuclear pore complex density and integrity
Biochem Biophys Res Commun, 499 (3), 570-576
DOI 10.1016/j.bbrc.2018.03.191, PubMed 29596829 -
Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding
Nat Commun, 9 (1), 3665
DOI 10.1038/s41467-018-05578-7, PubMed 30202009 -
RNA m6A methylation participates in regulation of postnatal development of the mouse cerebellum
Genome Biol, 19 (1), 68
DOI 10.1186/s13059-018-1435-z, PubMed 29855379 -
Key Residues Affecting Transglycosylation Activity in Family 18 Chitinases: Insights into Donor and Acceptor Subsites
Biochemistry, 57 (29), 4325-4337
DOI 10.1021/acs.biochem.8b00381, PubMed 29939724 -
Biallelic variants in KIF14 cause intellectual disability with microcephaly
Eur J Hum Genet, 26 (3), 330-339
DOI 10.1038/s41431-017-0088-9, PubMed 29343805 -
Donor-derived strongyloidiasis after organ transplantation in Norway
Transpl Infect Dis, 21 (1), e13008
DOI 10.1111/tid.13008, PubMed 30295406 -
An Estimate of the Burden of Fungal Disease in Norway
J Fungi (Basel), 4 (1)
DOI 10.3390/jof4010029, PubMed 29466284 -
Temporal trends of transmitted HIV drug resistance in a multinational seroconversion cohort
AIDS, 32 (2), 161-169
DOI 10.1097/QAD.0000000000001689, PubMed 29112061 -
Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments
Mol Psychiatry, 25 (4), 732-749
DOI 10.1038/s41380-018-0226-y, PubMed 30127471 -
High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections
J Neuroinflammation, 15 (1), 327
DOI 10.1186/s12974-018-1366-3, PubMed 30470234 -
Neonatal Ogg1/Mutyh knockout mice have altered inflammatory gene response compared to wildtype mice in the brain and lung after hypoxia-reoxygenation
J Perinat Med, 47 (1), 114-124
DOI 10.1515/jpm-2018-0172, PubMed 30020889 -
Increased Levels of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Ischemic Stroke and Transient Ischemic Attack
J Am Heart Assoc, 7 (2)
DOI 10.1161/JAHA.117.006479, PubMed 29330254 -
Parental micronutrient deficiency distorts liver DNA methylation and expression of lipid genes associated with a fatty-liver-like phenotype in offspring
Sci Rep, 8 (1), 3055
DOI 10.1038/s41598-018-21211-5, PubMed 29445184 -
Ultracentrifugation versus kit exosome isolation: nanoLC-MS and other tools reveal similar performance biomarkers, but also contaminations
Future Sci OA, 5 (1), FSO359
DOI 10.4155/fsoa-2018-0088, PubMed 30652024 -
Serum Uric Acid as an Independent Risk Factor for the Presence and Severity of Early-Onset Coronary Artery Disease: A Case-Control Study
Dis Markers, 2018, 1236837
DOI 10.1155/2018/1236837, PubMed 30425752 -
Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm
Mol Cell, 71 (6), 973-985.e5
DOI 10.1016/j.molcel.2018.08.011, PubMed 30197295 -
Stratification by interferon-γ release assay level predicts risk of incident TB
Thorax, 73 (7), 652-661
DOI 10.1136/thoraxjnl-2017-211147, PubMed 29622693 -
Screening and Identification of Pregnancy Zone Protein and Leucine-Rich Alpha-2-Glycoprotein as Potential Serum Biomarkers for Early-Onset Myocardial Infarction using Protein Profile Analysis
Proteomics Clin Appl, 13 (3), e1800079
DOI 10.1002/prca.201800079, PubMed 30411527 -
GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells
Haematologica, Online ahead of print (in press) (Retracted)
DOI 10.3324/haematol.2018.189399, PubMed 29748445 -
A Systems Approach to Study Immuno- and Neuro-Modulatory Properties of Antiviral Agents
Viruses, 10 (8)
DOI 10.3390/v10080423, PubMed 30103549
Publications 2017
-
How to: identify non-tuberculous Mycobacterium species using MALDI-TOF mass spectrometry
Clin Microbiol Infect, 24 (6), 599-603
DOI 10.1016/j.cmi.2017.11.012, PubMed 29174730 -
Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1
Sci Rep, 7 (1), 7199
DOI 10.1038/s41598-017-07314-5, PubMed 28775312 -
Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach
J Med Chem, 60 (24), 10013-10025
DOI 10.1021/acs.jmedchem.7b00883, PubMed 29155568 -
High incidence of maternal parvovirus B19 infection in a large unselected population-based pregnancy cohort in Norway
J Clin Virol, 94, 57-62
DOI 10.1016/j.jcv.2017.07.010, PubMed 28759773 -
Integrative whole-genome sequence analysis reveals roles of regulatory mutations in BCL6 and BCL2 in follicular lymphoma
Sci Rep, 7 (1), 7040
DOI 10.1038/s41598-017-07226-4, PubMed 28765546 -
Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function
Arterioscler Thromb Vasc Biol, 37 (6), 1157-1167
DOI 10.1161/ATVBAHA.116.308187, PubMed 28408371 -
Comparative proteomic analysis of Neisseria meningitidis wildtype and dprA null mutant strains links DNA processing to pilus biogenesis
BMC Microbiol, 17 (1), 96
DOI 10.1186/s12866-017-1004-8, PubMed 28431522 -
Nε- and O-Acetylation in Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains: Proteins Involved in Bioenergetics, Virulence, and Antimicrobial Resistance Are Acetylated
J Proteome Res, 16 (11), 4045-4059
DOI 10.1021/acs.jproteome.7b00429, PubMed 28920697 -
Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication
Nucleic Acids Res, 45 (14), 8291-8301
DOI 10.1093/nar/gkx476, PubMed 28575236 -
Bacteriology in uncomplicated urinary tract infections in Norwegian general practice from 2001-2015
BJGP Open, 1 (4), bjgpopen17X101145
DOI 10.3399/bjgpopen17X101145, PubMed 30564685 -
[Tattooed norwegian tourist with fever and rashes]
Tidsskr Nor Laegeforen, 137 (3), 205-207
DOI 10.4045/tidsskr.16.0710, PubMed 28181759 -
A non-canonical mismatch repair pathway in prokaryotes
Nat Commun, 8, 14246
DOI 10.1038/ncomms14246, PubMed 28128207 -
Regulation of tRNA synthesis by posttranslational modifications of RNA polymerase III subunits
Biochim Biophys Acta Gene Regul Mech, 1861 (4), 310-319
DOI 10.1016/j.bbagrm.2017.11.001, PubMed 29127063 -
TORC1-dependent sumoylation of Rpc82 promotes RNA polymerase III assembly and activity
Proc Natl Acad Sci U S A, 114 (5), 1039-1044
DOI 10.1073/pnas.1615093114, PubMed 28096404 -
High Prevalence of Humoral and Cellular Immunity to Influenza Viruses in Preschool Children Living in Addis Ababa, Ethiopia
Open Forum Infect Dis, 4 (1), ofx026
DOI 10.1093/ofid/ofx026, PubMed 28480294 -
Epidemiology and spa-type diversity of meticillin-resistant Staphylococcus aureus in community and healthcare settings in Norway
J Hosp Infect, 100 (3), 316-321
DOI 10.1016/j.jhin.2017.12.019, PubMed 29288777 -
Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages
Biochem Biophys Res Commun, 491 (2), 442-448
DOI 10.1016/j.bbrc.2017.07.070, PubMed 28712870 -
Phenotypes of dnaXE145A Mutant Cells Indicate that the Escherichia coli Clamp Loader Has a Role in the Restart of Stalled Replication Forks
J Bacteriol, 199 (24)
DOI 10.1128/JB.00412-17, PubMed 28947673 -
Structural determinants of bacterial lytic polysaccharide monooxygenase functionality
J Biol Chem, 293 (4), 1397-1412
DOI 10.1074/jbc.M117.817130, PubMed 29222333 -
The helicase DinG responds to stress due to DNA double strand breaks
PLoS One, 12 (11), e0187900
DOI 10.1371/journal.pone.0187900, PubMed 29121674 -
Applying tuberculosis management time to measure the tuberculosis infectious pool at a local level in Ethiopia
Infect Dis Poverty, 6 (1), 156
DOI 10.1186/s40249-017-0371-6, PubMed 29137661 -
Rotavirus detection in bulk stool and rectal swab specimens in children with acute gastroenteritis in Norway
J Clin Virol, 97, 50-53
DOI 10.1016/j.jcv.2017.10.017, PubMed 29107766 -
A TCRα framework-centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions
JCI Insight, 2 (17)
DOI 10.1172/jci.insight.95193, PubMed 28878121 -
Recovery of CYP3A Phenotype after Kidney Transplantation
Drug Metab Dispos, 45 (12), 1260-1265
DOI 10.1124/dmd.117.078030, PubMed 28928137 -
DprA from Neisseria meningitidis: properties and role in natural competence for transformation
Microbiology (Reading), 163 (7), 1016-1029
DOI 10.1099/mic.0.000489, PubMed 28696187 -
Draft Genome Sequences of Candida glabrata Isolates 1A, 1B, 2A, 2B, 3A, and 3B
Genome Announc, 5 (10)
DOI 10.1128/genomeA.00328-16, PubMed 28280017 -
erm gene distribution among Norwegian Bacteroides isolates and evaluation of phenotypic tests to detect inducible clindamycin resistance in Bacteroides species
Anaerobe, 47, 226-232
DOI 10.1016/j.anaerobe.2017.06.004, PubMed 28602805 -
ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage
Cell Death Dis, 8 (7), e2947
DOI 10.1038/cddis.2017.343, PubMed 28726787 -
Gene expression profiles in preterm infants on continuous long‑term oxygen therapy suggest reduced oxidative stress‑dependent signaling during hypoxia
Mol Med Rep, 15 (4), 1513-1526
DOI 10.3892/mmr.2017.6185, PubMed 28259955 -
Visualization and Live Imaging of Oligodendrocyte Organelles in Organotypic Brain Slices Using Adeno-associated Virus and Confocal Microscopy
J Vis Exp (128)
DOI 10.3791/56237, PubMed 29155726 -
NucDiff: in-depth characterization and annotation of differences between two sets of DNA sequences
BMC Bioinformatics, 18 (1), 338
DOI 10.1186/s12859-017-1748-z, PubMed 28701187 -
Impact of extensive antibiotic treatment on faecal carriage of antibiotic-resistant enterobacteria in children in a low resistance prevalence setting
PLoS One, 12 (11), e0187618
DOI 10.1371/journal.pone.0187618, PubMed 29112974 -
High-Sensitivity Troponin T vs I in Acute Coronary Syndrome: Prediction of Significant Coronary Lesions and Long-term Prognosis
Acta Bioquim. Clin. Latinoam., 51 (3), 395-407 -
Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation
Cell Discov, 3, 17013
DOI 10.1038/celldisc.2017.13, PubMed 28529766 -
Mitochondrial transcription factor A (TFAM) rs1937 and AP endonuclease 1 (APE1) rs1130409 alleles are associated with reduced cognitive performance
Neurosci Lett, 645, 46-52
DOI 10.1016/j.neulet.2017.02.062, PubMed 28242328 -
5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin
J Exp Clin Cancer Res, 36 (1), 187
DOI 10.1186/s13046-017-0662-6, PubMed 29258566 -
Loss of prion protein induces a primed state of type I interferon-responsive genes
PLoS One, 12 (6), e0179881
DOI 10.1371/journal.pone.0179881, PubMed 28651013 -
Whole blood gene expression in adolescent chronic fatigue syndrome: an exploratory cross-sectional study suggesting altered B cell differentiation and survival
J Transl Med, 15 (1), 102
DOI 10.1186/s12967-017-1201-0, PubMed 28494812 -
Tuberculosis Outbreak in an Educational Institution in Norway
J Clin Microbiol, 55 (5), 1327-1333
DOI 10.1128/JCM.01152-16, PubMed 28202795 -
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture
Cell Rep, 18 (1), 82-92
DOI 10.1016/j.celrep.2016.12.009, PubMed 28052262 -
Glycosylated Chromogranin A in Heart Failure: Implications for Processing and Cardiomyocyte Calcium Homeostasis
Circ Heart Fail, 10 (2)
DOI 10.1161/CIRCHEARTFAILURE.116.003675, PubMed 28209766 -
Metabolism and DNA repair shape a specific modification pattern in mitochondrial DNA
Mitochondrion, 40, 16-28
DOI 10.1016/j.mito.2017.09.002, PubMed 28893634 -
SeqA structures behind Escherichia coli replication forks affect replication elongation and restart mechanisms
Nucleic Acids Res, 45 (11), 6471-6485
DOI 10.1093/nar/gkx263, PubMed 28407100 -
The elemental role of iron in DNA synthesis and repair
Metallomics, 9 (11), 1483-1500
DOI 10.1039/c7mt00116a, PubMed 28879348 -
Characterization of the Phospho-Adhesome by Mass Spectrometry-Based Proteomics
Methods Mol Biol, 1636, 235-251
DOI 10.1007/978-1-4939-7154-1_15, PubMed 28730483 -
No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice
Sci Rep, 7 (1), 4384
DOI 10.1038/s41598-017-04472-4, PubMed 28663564 -
Novel UCHL1 mutations reveal new insights into ubiquitin processing
Hum Mol Genet, 26 (6), 1031-1040
DOI 10.1093/hmg/ddw391, PubMed 28007905 -
Novel UCHL1 mutations reveal new insights into ubiquitin processing
Hum Mol Genet, 26 (6), 1217-1218
DOI 10.1093/hmg/ddx072, PubMed 28334853 -
[Atypical optic neuritis]
Tidsskr Nor Laegeforen, 137 (10), 731
DOI 10.4045/tidsskr.16.1063, PubMed 28551973 -
8-oxoguanine DNA glycosylase (Ogg1) controls hepatic gluconeogenesis
DNA Repair (Amst), 61, 56-62
DOI 10.1016/j.dnarep.2017.11.008, PubMed 29207315 -
Role of the DNA repair glycosylase OGG1 in the activation of murine splenocytes
DNA Repair (Amst), 58, 13-20
DOI 10.1016/j.dnarep.2017.08.005, PubMed 28843610 -
No associations established between single nucleotide polymorphisms in human Toll-like receptor 2 and Toll-interacting protein and Staphylococcus aureus bloodstream infections
APMIS, 125 (10), 927-932
DOI 10.1111/apm.12734, PubMed 28736863 -
TANKYRASE Inhibition Enhances the Antiproliferative Effect of PI3K and EGFR Inhibition, Mutually Affecting β-CATENIN and AKT Signaling in Colorectal Cancer
Mol Cancer Res, 16 (3), 543-553
DOI 10.1158/1541-7786.MCR-17-0362, PubMed 29222171 -
Endothelial IL-33 Expression Is Augmented by Adenoviral Activation of the DNA Damage Machinery
J Immunol, 198 (8), 3318-3325
DOI 10.4049/jimmunol.1600054, PubMed 28258201 -
Mutations affecting the transmembrane domain of the LDL receptor: impact of charged residues on the membrane insertion
Hum Mol Genet, 26 (9), 1634-1642
DOI 10.1093/hmg/ddx068, PubMed 28334946 -
Evolution of the cAMP-dependent protein kinase (PKA) catalytic subunit isoforms
PLoS One, 12 (7), e0181091
DOI 10.1371/journal.pone.0181091, PubMed 28742821 -
The burden of and risk factors for active trachoma in the North and South Wollo Zones of Amhara Region, Ethiopia: a cross-sectional study
Infect Dis Poverty, 6 (1), 143
DOI 10.1186/s40249-017-0358-3, PubMed 28988540 -
Effect of water, sanitation and hygiene interventions on active trachoma in North and South Wollo zones of Amhara Region, Ethiopia: A Quasi-experimental study
PLoS Negl Trop Dis, 11 (11), e0006080
DOI 10.1371/journal.pntd.0006080, PubMed 29125849 -
ALKBH5-dependent m6A demethylation controls splicing and stability of long 3'-UTR mRNAs in male germ cells
Proc Natl Acad Sci U S A, 115 (2), E325-E333
DOI 10.1073/pnas.1717794115, PubMed 29279410 -
A Young, Immunocompetent Woman with Small Bowel and Hepatic Mucormycosis Successfully Treated with Aggressive Surgical Debridements and Antifungal Therapy
Case Rep Infect Dis, 2017, 4173246
DOI 10.1155/2017/4173246, PubMed 29435377 -
Prevalence and associated factors of tuberculosis and diabetes mellitus comorbidity: A systematic review
PLoS One, 12 (4), e0175925
DOI 10.1371/journal.pone.0175925, PubMed 28430796 -
BIIB021: A novel inhibitor to heat shock protein 90-addicted oncology
Tumour Biol, 39 (4), 1010428317698355
DOI 10.1177/1010428317698355, PubMed 28443462 -
Comparative Proteomic Analysis of Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains Reveals Differentially Abundant Proteins Linked to Slow Growth and Virulence
Front Microbiol, 8, 795
DOI 10.3389/fmicb.2017.00795, PubMed 28536560 -
The association between MTHFR gene C677T polymorphism and ALL risk based on a meta-analysis involving 17,469 subjects
Clin Chim Acta, 466, 85-92
DOI 10.1016/j.cca.2017.01.001, PubMed 28062297 -
No effect of treatment with intravenous ganciclovir on Epstein-Barr virus viremia demonstrated after pediatric liver transplantation
Pediatr Transplant, 21 (6)
DOI 10.1111/petr.13010, PubMed 28653462 -
Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy
PLoS One, 12 (3), e0168182
DOI 10.1371/journal.pone.0168182, PubMed 28288181
Publications 2016
-
ALKBHs-facilitated RNA modifications and de-modifications
DNA Repair (Amst), 44, 87-91
DOI 10.1016/j.dnarep.2016.05.026, PubMed 27237585 -
Diversity and antifungal susceptibility of Norwegian Candida glabrata clinical isolates
J Oral Microbiol, 8, 29849
DOI 10.3402/jom.v8.29849, PubMed 26861194 -
N-Acetylcysteine Amide Exerts Possible Neuroprotective Effects in Newborn Pigs after Perinatal Asphyxia
Neonatology, 111 (1), 12-21
DOI 10.1159/000447255, PubMed 27497671 -
Characterization of the Neisseria meningitidis Helicase RecG
PLoS One, 11 (10), e0164588
DOI 10.1371/journal.pone.0164588, PubMed 27736945 -
Correction for Blomfeldt et al., Molecular Characterization of Methicillin-Sensitive Staphylococcus aureus Isolates from Bacteremic Patients in a Norwegian University Hospital
J Clin Microbiol, 54 (9), 2404
DOI 10.1128/JCM.01436-16, PubMed 27578159 -
Burden of Rotavirus Disease in Norway: Using National Registries for Public Health Research
Pediatr Infect Dis J, 35 (4), 396-400
DOI 10.1097/INF.0000000000001055, PubMed 26974747 -
Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition
Nature, 537 (7621), 548-552
DOI 10.1038/nature19360, PubMed 27626377 -
Analysis of Cell Lineage Trees by Exact Bayesian Inference Identifies Negative Autoregulation of Nanog in Mouse Embryonic Stem Cells
Cell Syst, 3 (5), 480-490.e13
DOI 10.1016/j.cels.2016.11.001, PubMed 27883891 -
Structural and Functional Analysis of a Lytic Polysaccharide Monooxygenase Important for Efficient Utilization of Chitin in Cellvibrio japonicus
J Biol Chem, 291 (14), 7300-12
DOI 10.1074/jbc.M115.700161, PubMed 26858252 -
TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity
J Immunol, 196 (8), 3452-3459
DOI 10.4049/jimmunol.1502601, PubMed 26962230 -
A novel Direct MIC-gradient Strip Method to screen for antibiotic-resistant faecal Enterobacteriaceae
J Microbiol Methods, 129, 94-97
DOI 10.1016/j.mimet.2016.08.007, PubMed 27526992 -
Total Delay Is Associated with Unfavorable Treatment Outcome among Pulmonary Tuberculosis Patients in West Gojjam Zone, Northwest Ethiopia: A Prospective Cohort Study
PLoS One, 11 (7), e0159579
DOI 10.1371/journal.pone.0159579, PubMed 27442529 -
Patients' and health system's delays in the diagnosis and treatment of new pulmonary tuberculosis patients in West Gojjam Zone, Northwest Ethiopia: a cross-sectional study
BMC Infect Dis, 16 (1), 673
DOI 10.1186/s12879-016-1995-z, PubMed 27836012 -
Qualitative Assessment of Challenges in Tuberculosis Control in West Gojjam Zone, Northwest Ethiopia: Health Workers' and Tuberculosis Control Program Coordinators' Perspectives
Tuberc Res Treat, 2016, 2036234
DOI 10.1155/2016/2036234, PubMed 27066271 -
Differences in epidemiology of candidaemia in the Nordic countries - what is to blame?
Mycoses, 60 (1), 11-19
DOI 10.1111/myc.12535, PubMed 27464892 -
Risk Factors for Long-Term Mortality after Hospitalization for Community-Acquired Pneumonia: A 5-Year Prospective Follow-Up Study
PLoS One, 11 (2), e0148741
DOI 10.1371/journal.pone.0148741, PubMed 26849359 -
Neil3 induced neurogenesis protects against prion disease during the clinical phase
Sci Rep, 6, 37844
DOI 10.1038/srep37844, PubMed 27886261 -
Molecular Analysis of the GJB2 Gene in Iraqi Patients with Sensorineural Non-Syndromic Hearing Loss
Jordan Medical Journal, 50 (3), 145-155
PublikaID 236 -
A Cross-Sectional Study of the Prevalence of Gastrointestinal Symptoms and Pathology in Patients With Common Variable Immunodeficiency
Am J Gastroenterol, 111 (10), 1467-1475
DOI 10.1038/ajg.2016.329, PubMed 27527747 -
Reversible RNA modifications in meiosis and pluripotency
Nat Methods, 14 (1), 18-22
DOI 10.1038/nmeth.4111, PubMed 28032624 -
Oxidized C5-methyl cytosine bases in DNA: 5-Hydroxymethylcytosine; 5-formylcytosine; and 5-carboxycytosine
Free Radic Biol Med, 107, 62-68
DOI 10.1016/j.freeradbiomed.2016.11.038, PubMed 27890639 -
Open-Source Sequence Clustering Methods Improve the State Of the Art
mSystems, 1 (1)
DOI 10.1128/mSystems.00003-15, PubMed 27822515 -
Mutually exclusive RNA secondary structures regulate translation initiation of DinQ in Escherichia coli
RNA, 22 (11), 1739-1749
DOI 10.1261/rna.058461.116, PubMed 27651528 -
Sequencing of FTO and ALKBH5 in men undergoing infertility work-up identifies an infertility-associated variant and two missense mutations
Fertil Steril, 105 (5), 1170-1179.e5
DOI 10.1016/j.fertnstert.2016.01.002, PubMed 26820768 -
A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain
Neurobiol Aging, 48, 34-47
DOI 10.1016/j.neurobiolaging.2016.08.005, PubMed 27639119 -
Altered DNA base excision repair profile in brain tissue and blood in Alzheimer's disease
Mol Brain, 9 (1), 61
DOI 10.1186/s13041-016-0237-z, PubMed 27234294 -
ALKBH1-Mediated tRNA Demethylation Regulates Translation
Cell, 167 (3), 816-828.e16
DOI 10.1016/j.cell.2016.09.038, PubMed 27745969 -
ALKBH1-Mediated tRNA Demethylation Regulates Translation
Cell, 167 (7), 1897
DOI 10.1016/j.cell.2016.11.045, PubMed 27984735 -
Fat and vitamin intakes during pregnancy have stronger relations with a pro-inflammatory maternal microbiota than does carbohydrate intake
Microbiome, 4 (1), 55
DOI 10.1186/s40168-016-0200-3, PubMed 27756413 -
Pathogenic variants in KCTD7 perturb neuronal K+ fluxes and glutamine transport
Brain, 139 (Pt 12), 3109-3120
DOI 10.1093/brain/aww244, PubMed 27742667 -
Effects of Anthocyanins on CAG Repeat Instability and Behaviour in Huntington's Disease R6/1 Mice
PLoS Curr, 8
DOI 10.1371/currents.hd.58d04209ab6d5de0844db7ef5628ff67, PubMed 27540492 -
The Mycobacterium tuberculosis transcriptional landscape under genotoxic stress
BMC Genomics, 17 (1), 791
DOI 10.1186/s12864-016-3132-1, PubMed 27724857 -
Regulation of Human Endonuclease V Activity and Relocalization to Cytoplasmic Stress Granules
J Biol Chem, 291 (41), 21786-21801
DOI 10.1074/jbc.M116.730911, PubMed 27573237 -
Crystal structure and MD simulation of mouse EndoV reveal wedge motif plasticity in this inosine-specific endonuclease
Sci Rep, 6, 24979
DOI 10.1038/srep24979, PubMed 27108838 -
Genomic characterization of Mycobacterium tuberculosis lineage 7 and a proposed name: 'Aethiops vetus'
Microb Genom, 2 (6), e000063
DOI 10.1099/mgen.0.000063, PubMed 28348856 -
Role of ALKBH1 in the Core Transcriptional Network of Embryonic Stem Cells
Cell Physiol Biochem, 38 (1), 173-84
DOI 10.1159/000438619, PubMed 26765775 -
PML regulates neuroprotective innate immunity and neuroblast commitment in a hypoxic-ischemic encephalopathy model
Cell Death Dis, 7 (7), e2320
DOI 10.1038/cddis.2016.223, PubMed 27468695 -
Efficient and Reliable Production of Vectors for the Study of the Repair, Mutagenesis, and Phenotypic Consequences of Defined DNA Damage Lesions in Mammalian Cells
PLoS One, 11 (6), e0158581
DOI 10.1371/journal.pone.0158581, PubMed 27362559 -
Axitinib blocks Wnt/β-catenin signaling and directs asymmetric cell division in cancer
Proc Natl Acad Sci U S A, 113 (33), 9339-44
DOI 10.1073/pnas.1604520113, PubMed 27482107 -
DNA base modifications in honey bee and fruit fly genomes suggest an active demethylation machinery with species- and tissue-specific turnover rates
Biochemistry and Biophysics Reports, 6, 9-15
DOI 10.1016/j.bbrep.2016.02.011, PublikaID 234 -
DNA base modifications in honey bee and fruit fly genomes suggest an active demethylation machinery with species- and tissue-specific turnover rates
Biochem Biophys Rep, 6, 9-15
DOI 10.1016/j.bbrep.2016.02.011, PubMed 28955859 -
VSEARCH: a versatile open source tool for metagenomics
PeerJ, 4, e2584
DOI 10.7717/peerj.2584, PubMed 27781170 -
Rapid Bedside Inactivation of Ebola Virus for Safe Nucleic Acid Tests
J Clin Microbiol, 54 (10), 2521-9
DOI 10.1128/JCM.00346-16, PubMed 27466385 -
cnvScan: a CNV screening and annotation tool to improve the clinical utility of computational CNV prediction from exome sequencing data
BMC Genomics, 17, 51
DOI 10.1186/s12864-016-2374-2, PubMed 26764020 -
3CAPS - a structural AP-site analogue as a tool to investigate DNA base excision repair
Nucleic Acids Res, 44 (5), 2187-98
DOI 10.1093/nar/gkv1520, PubMed 26733580 -
Circulating cell-free DNA is elevated in community-acquired bacterial pneumonia and predicts short-term outcome
J Infect, 73 (4), 383-6
DOI 10.1016/j.jinf.2016.07.011, PubMed 27452197 -
Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA
Free Radic Biol Med, 97, 386-397
DOI 10.1016/j.freeradbiomed.2016.07.001, PubMed 27381496 -
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice
Sci Rep, 6, 28337
DOI 10.1038/srep28337, PubMed 27328939 -
Parental vitamin deficiency affects the embryonic gene expression of immune-, lipid transport- and apolipoprotein genes
Sci Rep, 6, 34535
DOI 10.1038/srep34535, PubMed 27731423 -
Low level of MAp44, an inhibitor of the lectin complement pathway, and long-term graft and patient survival; a cohort study of 382 kidney recipients
BMC Nephrol, 17 (1), 148
DOI 10.1186/s12882-016-0373-9, PubMed 27760523 -
Collectin Liver 1 and Collectin Kidney 1 of the Lectin Complement Pathway Are Associated With Mortality After Kidney Transplantation
Am J Transplant, 17 (1), 265-271
DOI 10.1111/ajt.13933, PubMed 27341702 -
A potential founder variant in CARMIL2/RLTPR in three Norwegian families with warts, molluscum contagiosum, and T-cell dysfunction
Mol Genet Genomic Med, 4 (6), 604-616
DOI 10.1002/mgg3.237, PubMed 27896283 -
Fatal primary amoebic meningoencephalitis in a Norwegian tourist returning from Thailand
JMM Case Rep, 3 (3), e005042
DOI 10.1099/jmmcr.0.005042, PubMed 28348761 -
Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells
Epigenetics Chromatin, 9, 21
DOI 10.1186/s13072-016-0070-8, PubMed 27252783 -
Standardised surveillance of Clostridium difficile infection in European acute care hospitals: a pilot study, 2013
Euro Surveill, 21 (29)
DOI 10.2807/1560-7917.ES.2016.21.29.30293, PubMed 27472820 -
Effect of Hydroxymethylcytosine on the Structure and Stability of Holliday Junctions
Biochemistry, 55 (41), 5781-5789
DOI 10.1021/acs.biochem.6b00801, PubMed 27653243 -
Removal of aquaporin-4 from glial and ependymal membranes causes brain water accumulation
Mol Cell Neurosci, 77, 47-52
DOI 10.1016/j.mcn.2016.10.004, PubMed 27751903 -
Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism
Nat Commun, 7, 10806
DOI 10.1038/ncomms10806, PubMed 26932196 -
Prevalence and Associated Factors of Diabetes Mellitus among Tuberculosis Patients in South-Eastern Amhara Region, Ethiopia: A Cross Sectional Study
PLoS One, 11 (1), e0147621
DOI 10.1371/journal.pone.0147621, PubMed 26808967 -
Diabetes mellitus is associated with increased mortality during tuberculosis treatment: a prospective cohort study among tuberculosis patients in South-Eastern Amahra Region, Ethiopia
Infect Dis Poverty, 5, 22
DOI 10.1186/s40249-016-0115-z, PubMed 27009088 -
Assessment of health system challenges and opportunities for possible integration of diabetes mellitus and tuberculosis services in South-Eastern Amhara Region, Ethiopia: a qualitative study
BMC Health Serv Res, 16, 135
DOI 10.1186/s12913-016-1378-6, PubMed 27095028 -
Deciphering the recent phylogenetic expansion of the originally deeply rooted Mycobacterium tuberculosis lineage 7
BMC Evol Biol, 16 (1), 146
DOI 10.1186/s12862-016-0715-z, PubMed 27363525 -
Throat culture positivity rate and antibiotic susceptibility pattern of beta-hemolytic streptococci in children on secondary prophylaxis for rheumatic heart disease
BMC Infect Dis, 16 (1), 510
DOI 10.1186/s12879-016-1841-3, PubMed 27663649 -
Lessons Learned From a Randomized Study of Oral Valganciclovir Versus Parenteral Ganciclovir Treatment of Cytomegalovirus Disease in Solid Organ Transplant Recipients: The VICTOR Trial
Clin Infect Dis, 62 (9), 1154-60
DOI 10.1093/cid/ciw084, PubMed 26908810
Publications 2015
-
Skin Barrier Function and Staphylococcus aureus Colonization in Vestibulum Nasi and Fauces in Healthy Infants and Infants with Eczema: A Population-Based Cohort Study
PLoS One, 10 (6), e0130145
DOI 10.1371/journal.pone.0130145, PubMed 26070153 -
Topical treatment with fresh human milk versus emollient on atopic eczema spots in young children: a small, randomized, split body, controlled, blinded pilot study
BMC Dermatol, 15, 7
DOI 10.1186/s12895-015-0027-9, PubMed 25935520 -
Polyclonal Expansion of NKG2C(+) NK Cells in TAP-Deficient Patients
Front Immunol, 6, 507
DOI 10.3389/fimmu.2015.00507, PubMed 26500647 -
Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice
Cell Rep, 13 (12), 2671-8
DOI 10.1016/j.celrep.2015.12.001, PubMed 26711335 -
Maternal Colonization with Group B Streptococcus Is Associated with an Increased Rate of Infants Transferred to the Neonatal Intensive Care Unit
Neonatology, 108 (3), 157-63
DOI 10.1159/000434716, PubMed 26182960 -
Results of comprehensive diagnostic work-up in 'idiopathic' dilated cardiomyopathy
Open Heart, 2 (1), e000271
DOI 10.1136/openhrt-2015-000271, PubMed 26468400 -
SUMO-regulated transcription: challenging the dogma
Bioessays, 37 (10), 1095-105
DOI 10.1002/bies.201500065, PubMed 26354225 -
Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes
Genome Res, 25 (6), 897-906
DOI 10.1101/gr.185793.114, PubMed 25800674 -
Micro chromatin immunoprecipitation (μChIP) from early mammalian embryos
Methods Mol Biol, 1222, 227-45
DOI 10.1007/978-1-4939-1594-1_17, PubMed 25287350 -
Staphylococcal α-hemolysin is neurotoxic and causes lysis of brain cells in vivo and in vitro
Neurotoxicology, 48, 61-7
DOI 10.1016/j.neuro.2015.03.001, PubMed 25757835 -
Structural basis for incision at deaminated adenines in DNA and RNA by endonuclease V
Prog Biophys Mol Biol, 117 (2-3), 134-142
DOI 10.1016/j.pbiomolbio.2015.03.005, PubMed 25824682 -
Sumo and the cellular stress response
Cell Div, 10, 4
DOI 10.1186/s13008-015-0010-1, PubMed 26101541 -
Toxoplasma prevalence among pregnant women in Norway: a cross-sectional study
APMIS, 123 (4), 321-5
DOI 10.1111/apm.12354, PubMed 25628065 -
Persistent Low Toxoplasma IgG Avidity Is Common in Pregnancy: Experience from Antenatal Testing in Norway
PLoS One, 10 (12), e0145519
DOI 10.1371/journal.pone.0145519, PubMed 26714282 -
Generalized epilepsy in a family with basal ganglia calcifications and mutations in SLC20A2 and CHRNB2
Eur J Med Genet, 58 (11), 624-8
DOI 10.1016/j.ejmg.2015.10.005, PubMed 26475232 -
The Inner Membrane Protein PilG Interacts with DNA and the Secretin PilQ in Transformation
PLoS One, 10 (8), e0134954
DOI 10.1371/journal.pone.0134954, PubMed 26248334 -
Lysine Methylation of the Valosin-Containing Protein (VCP) Is Dispensable for Development and Survival of Mice
PLoS One, 10 (11), e0141472
DOI 10.1371/journal.pone.0141472, PubMed 26544960 -
Functional analysis of an unusual type IV pilus in the Gram-positive Streptococcus sanguinis
Mol Microbiol, 99 (2), 380-92
DOI 10.1111/mmi.13237, PubMed 26435398 -
Protein Phosphatase 1c Associated with the Cardiac Sodium Calcium Exchanger 1 Regulates Its Activity by Dephosphorylating Serine 68-phosphorylated Phospholemman
J Biol Chem, 291 (9), 4561-79
DOI 10.1074/jbc.M115.677898, PubMed 26668322 -
Development and structural analysis of adenosine site binding tankyrase inhibitors
Bioorg Med Chem Lett, 26 (2), 328-333
DOI 10.1016/j.bmcl.2015.12.018, PubMed 26706174 -
Corynebacterium pseudotuberculosis Pneumonia in a Veterinary Student Infected During Laboratory Work
Open Forum Infect Dis, 2 (2), ofv053
DOI 10.1093/ofid/ofv053, PubMed 26380345 -
Mutation analysis in Norwegian families with hereditary hemorrhagic telangiectasia: founder mutations in ACVRL1
Clin Genet, 89 (2), 182-6
DOI 10.1111/cge.12612, PubMed 25970827 -
Twenty-two years of candidaemia surveillance: results from a Norwegian national study
Clin Microbiol Infect, 21 (10), 938-45
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Transmission of HIV Drug Resistance and the Predicted Effect on Current First-line Regimens in Europe
Clin Infect Dis, 62 (5), 655-663
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Etiology of community-acquired pneumonia and diagnostic yields of microbiological methods: a 3-year prospective study in Norway
BMC Infect Dis, 15, 64
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Hemophagocytic lymphohistiocytosis in leprosy
Lepr Rev, 86 (4), 403-6
PubMed 26964439 -
A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation
Genes Dev, 29 (19), 2037-53
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Endogenous DNA Damage and Repair Enzymes: -A short summary of the scientific achievements of Tomas Lindahl, Nobel Laureate in Chemistry 2015
Genomics Proteomics Bioinformatics, 14 (3), 122-125
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Correction: TCTP is an androgen-regulated gene implicated in prostate cancer
PLoS One, 10 (5), e0128727
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Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure
Am J Physiol Heart Circ Physiol, 309 (3), H434-49
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Hcmv-miR-UL22A-5p: A Biomarker in Transplantation With Broad Impact on Host Gene Expression and Potential Immunological Implications
Am J Transplant, 15 (7), 1893-902
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Slug-dependent upregulation of L1CAM is responsible for the increased invasion potential of pancreatic cancer cells following long-term 5-FU treatment
PLoS One, 10 (4), e0123684
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Susceptibility to infections, without concomitant hyper-IgE, reported in 1976, is caused by hypomorphic mutation in the phosphoglucomutase 3 (PGM3) gene
Clin Immunol, 161 (2), 366-72
DOI 10.1016/j.clim.2015.10.002, PubMed 26482871 -
Synthetic Routes to N-9 Alkylated 8-Oxoguanines; Weak Inhibitors of the Human DNA Glycosylase OGG1
Molecules, 20 (9), 15944-65
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Swarm v2: highly-scalable and high-resolution amplicon clustering
PeerJ, 3, e1420
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Evidence for the critical role of a secondary site rpoB mutation in the compensatory evolution and successful transmission of an MDR tuberculosis outbreak strain
J Antimicrob Chemother, 71 (2), 324-32
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Structural and functional characterization of a small chitin-active lytic polysaccharide monooxygenase domain of a multi-modular chitinase from Jonesia denitrificans
FEBS Lett, 590 (1), 34-42
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Base-excision repair and beyond —A short summary attributed to scientific achievements of Tomas Lindahl, Nobel Prize Laureate in Chemistry 2015
Science China Life Sciences, 59 (1), 89-92
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Base-excision repair and beyond --A short summary attributed to scientific achievements of Tomas Lindahl, Nobel Prize Laureate in Chemistry 2015
Sci China Life Sci, 59 (1), 89-92
DOI 10.1007/s11427-015-4983-4, PubMed 26676642 -
Structural Features of a Bacteroidetes-Affiliated Cellulase Linked with a Polysaccharide Utilization Locus
Sci Rep, 5, 11666
DOI 10.1038/srep11666, PubMed 26133573 -
Expression profiling of wild type and β-catenin gene disrupted human BxPC-3 pancreatic adenocarcinoma cells
Genom Data, 4, 150-2
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Secretoneurin is a novel prognostic cardiovascular biomarker associated with cardiomyocyte calcium handling
J Am Coll Cardiol, 65 (4), 339-351
DOI 10.1016/j.jacc.2014.10.065, PubMed 25634832 -
Non-homologous functions of the AlkB homologs
J Mol Cell Biol, 7 (6), 494-504
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Two cases of acute severe flaccid myelitis associated with enterovirus D68 infection in children, Norway, autumn 2014
Euro Surveill, 20 (10), 21062
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Reduced expression of aquaporins in human intestinal mucosa in early stage inflammatory bowel disease
Clin Exp Gastroenterol, 8, 49-67
DOI 10.2147/CEG.S70119, PubMed 25624769 -
Hearing loss in children in Ostfold county 2000-09
Tidsskr. Nor. Laegeforen., 135 (6), 511 -
[Re: Hearing loss in children in Östfold county 2000-09]
Tidsskr Nor Laegeforen, 135 (6), 513
DOI 10.4045/tidsskr.15.0262, PubMed 25806741 -
A worrying trend in weight-adjusted paediatric antibiotic use in a Norwegian tertiary care hospital
Acta Paediatr, 104 (7), 687-92
DOI 10.1111/apa.12994, PubMed 25753620 -
Staphylococcus lugdunensis endocarditis following vasectomy--report of a case history and review of the literature
APMIS, 123 (8), 726-9
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An in vitro Study of Protein Adsorption to Biocompatible Coatings
Stud Health Technol Inform, 211, 166-71
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Genetic variants in the DNA repair gene NEIL3 and the risk of myocardial infarction in a nested case-control study. The HUNT Study
DNA Repair (Amst), 28, 21-7
DOI 10.1016/j.dnarep.2015.01.013, PubMed 25703835 -
High ficolin-3 level at the time of transplantation is an independent risk factor for graft loss in kidney transplant recipients
Transplantation, 99 (4), 791-6
DOI 10.1097/TP.0000000000000422, PubMed 25222012 -
Mutation p.L799R in the LDLR, which affects the transmembrane domain of the LDLR, prevents membrane insertion and causes secretion of the mutant LDLR
Hum Mol Genet, 24 (20), 5836-44
DOI 10.1093/hmg/ddv304, PubMed 26220972 -
Structure, Dynamics, and Functionality of Tankyrase Inhibitor-Induced Degradasomes
Mol Cancer Res, 13 (11), 1487-501
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Increased osteoprotegerin predicts poor virological outcome during anticytomegalovirus therapy in solid organ transplant recipients
Transplantation, 99 (1), 100-5
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Analysis of mitochondrial DNA and RNA integrity by a real-time qPCR-based method
Methods Mol Biol, 1264, 97-106
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L-citrulline for protection of endothelial function from ADMA-induced injury in porcine coronary artery
Sci Rep, 5, 10987
DOI 10.1038/srep10987, PubMed 26046576 -
Levels of asymmetric dimethylarginine (ADMA), an endogenous nitric oxide synthase inhibitor, and risk of coronary artery disease: A meta-analysis based on 4713 participants
Eur J Prev Cardiol, 23 (5), 502-10
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Uracil-DNA Glycosylase UNG Promotes Tet-mediated DNA Demethylation
J Biol Chem, 291 (2), 731-8
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Transcriptome analysis of human OXR1 depleted cells reveals its role in regulating the p53 signaling pathway
Sci Rep, 5, 17409
DOI 10.1038/srep17409, PubMed 26616534 -
Mycobacterium tuberculosis lineage 7 strains are associated with prolonged patient delay in seeking treatment for pulmonary tuberculosis in Amhara Region, Ethiopia
J Clin Microbiol, 53 (4), 1301-9
DOI 10.1128/JCM.03566-14, PubMed 25673798
Publications 2014
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Mathematical and live meningococcal models for simple sequence repeat dynamics - coherent predictions and observations
PLoS One, 9 (7), e101637
DOI 10.1371/journal.pone.0101637, PubMed 24999629 -
Inosine in DNA and RNA
Curr Opin Genet Dev, 26, 116-23
DOI 10.1016/j.gde.2014.07.008, PubMed 25173738 -
Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding
J Biol Chem, 289 (19), 13492-502
DOI 10.1074/jbc.M114.549832, PubMed 24652290 -
Effect of football or strength training on functional ability and physical performance in untrained old men
Scand J Med Sci Sports, 24 Suppl 1, 76-85
DOI 10.1111/sms.12245, PubMed 24903323 -
Mitochondrial DNA damage and repair during ischemia-reperfusion injury of the heart
J Mol Cell Cardiol, 78, 9-22
DOI 10.1016/j.yjmcc.2014.11.010, PubMed 25446179 -
Development of DinQ from Escherichia coli as an anti-cell-envelope antibiotic
Int J Antimicrob Agents, 45 (2), 196-7
DOI 10.1016/j.ijantimicag.2014.10.005, PubMed 25465525 -
High frequency of enterovirus D68 in children hospitalised with respiratory illness in Norway, autumn 2014
Influenza Other Respir Viruses, 9 (2), 59-63
DOI 10.1111/irv.12300, PubMed 25534826 -
Comparison of PCR and serotyping of Group B Streptococcus in pregnant women: the Oslo GBS-study
J Microbiol Methods, 108, 31-5
DOI 10.1016/j.mimet.2014.11.001, PubMed 25447890 -
Intricacies of redoxome function demonstrated with a simple in vitro chemiluminescence method, with special reference to vitamin B12 as antioxidant
Scand J Immunol, 80 (6), 390-7
DOI 10.1111/sji.12220, PubMed 25345916 -
Socio-economic status and incident diabetes mellitus among employees in Denmark: a prospective analysis with 10-year follow-up
Diabet Med, 31 (12), 1559-62
DOI 10.1111/dme.12493, PubMed 24823972 -
Identification and characterization of a novel evolutionarily conserved lysine-specific methyltransferase targeting eukaryotic translation elongation factor 2 (eEF2)
J Biol Chem, 289 (44), 30499-30510
DOI 10.1074/jbc.M114.601658, PubMed 25231979 -
Metabolic pathways further increase the complexity of cell size control in budding yeast
Microb Cell, 1 (9), 276-278
DOI 10.15698/mic2014.09.167, PubMed 28362005 -
spa typing alone is not sufficient to demonstrate endemic establishment of meticillin-resistant Staphylococcus aureus in a low-prevalence country
J Hosp Infect, 88 (2), 72-7
DOI 10.1016/j.jhin.2014.06.008, PubMed 25085462 -
Brain infection with Staphylococcus aureus leads to high extracellular levels of glutamate, aspartate, γ-aminobutyric acid, and zinc
J Neurosci Res, 92 (12), 1792-800
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[Allogeneic stem-cell transplantation in adults 1985-2012: results and development]
Tidsskr Nor Laegeforen, 134 (16), 1569-75
DOI 10.4045/tidsskr.13.1415, PubMed 25178233 -
Genome Sequences of Corynebacterium pseudotuberculosis Strains 48252 (Human, Pneumonia), CS_10 (Lab Strain), Ft_2193/67 (Goat, Pus), and CCUG 27541
Genome Announc, 2 (5)
DOI 10.1128/genomeA.00869-14, PubMed 25189581 -
Dynamic RNA modifications in disease
Curr Opin Genet Dev, 26, 47-52
DOI 10.1016/j.gde.2014.05.006, PubMed 25005745 -
Massive parallel sequencing provides new perspectives on bacterial brain abscesses
J Clin Microbiol, 52 (6), 1990-7
DOI 10.1128/JCM.00346-14, PubMed 24671797 -
[Local food at exotic vacation]
Tidsskr Nor Laegeforen, 134 (2), 192-3
DOI 10.4045/tidsskr.13.1372, PubMed 24477156 -
Comparable Cellular Immune Responses in Patients with and without Antiretroviral Treatment after Immunization with HIV-1 P24, P17 and Tat Consensus Peptides (Vacc-5q)
J AIDS Clin Res, 5 (4), 1000294
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The novel EpCAM-targeting monoclonal antibody 3-17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines
MAbs, 6 (4), 1038-50
DOI 10.4161/mabs.28207, PubMed 24525727 -
An outbreak of enterotoxigenic Escherichia coli (ETEC) infection in Norway, 2012: a reminder to consider uncommon pathogens in outbreaks involving imported products
Epidemiol Infect, 143 (3), 486-93
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Swarm: robust and fast clustering method for amplicon-based studies
PeerJ, 2, e593
DOI 10.7717/peerj.593, PubMed 25276506 -
New carbocyclic nucleosides: synthesis of carbocyclic pseudoisocytidine and its analogs
Tetrahedron Lett., 55 (27), 3713-3716
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[A knot on the aquarium owner's hand]
Tidsskr Nor Laegeforen, 134 (7), 715
DOI 10.4045/tidsskr.13.1425, PubMed 24721859 -
Postpartum HELLP syndrome and subcapsular liver haematoma
BMJ Case Rep, 2014
DOI 10.1136/bcr-2013-202503, PubMed 24789156 -
A dominant STIM1 mutation causes Stormorken syndrome
Hum Mutat, 35 (5), 556-64
DOI 10.1002/humu.22544, PubMed 24619930 -
Hyperandrogenism and phenotypes of polycystic ovary syndrome are not associated with differences in obstetric outcomes
Acta Obstet Gynecol Scand, 94 (2), 204-11
DOI 10.1111/aogs.12545, PubMed 25417943 -
ALKBH4 depletion in mice leads to spermatogenic defects
PLoS One, 9 (8), e105113
DOI 10.1371/journal.pone.0105113, PubMed 25153837 -
Promyelocytic leukemia bodies tether to early endosomes during mitosis
Cell Cycle, 13 (11), 1749-55
DOI 10.4161/cc.28653, PubMed 24675887 -
DNA metabolism: bases of DNA repair and regulation
Nat Chem Biol, 10 (7), 487-8
DOI 10.1038/nchembio.1553, PubMed 24937064 -
Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombination
Nucleic Acids Res, 42 (21), 13280-93
DOI 10.1093/nar/gku1032, PubMed 25355512 -
Interaction with both domain I and III of albumin is required for optimal pH-dependent binding to the neonatal Fc receptor (FcRn)
J Biol Chem, 289 (50), 34583-94
DOI 10.1074/jbc.M114.587675, PubMed 25344603 -
Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies
J Biol Chem, 289 (24), 17228-39
DOI 10.1074/jbc.M113.522565, PubMed 24764301 -
A metagenomic study of the microbial communities in four parallel biogas reactors
Biotechnol Biofuels, 7 (1), 146
DOI 10.1186/s13068-014-0146-2, PubMed 25328537 -
The distribution of DNA damage is defined by region-specific susceptibility to DNA damage formation rather than repair differences
DNA Repair (Amst), 18, 44-51
DOI 10.1016/j.dnarep.2014.03.003, PubMed 24685126 -
Genome instability in Maple Syrup Urine Disease correlates with impaired mitochondrial biogenesis
Metabolism, 63 (8), 1063-70
DOI 10.1016/j.metabol.2014.05.003, PubMed 24928662 -
PGM3 mutations cause a congenital disorder of glycosylation with severe immunodeficiency and skeletal dysplasia
Am J Hum Genet, 95 (1), 96-107
DOI 10.1016/j.ajhg.2014.05.007, PubMed 24931394 -
Mutation G805R in the transmembrane domain of the LDL receptor gene causes familial hypercholesterolemia by inducing ectodomain cleavage of the LDL receptor in the endoplasmic reticulum
FEBS Open Bio, 4, 321-7
DOI 10.1016/j.fob.2014.03.007, PubMed 24918045 -
Disease mechanisms and clonidine treatment in adolescent chronic fatigue syndrome: a combined cross-sectional and randomized clinical trial
JAMA Pediatr, 168 (4), 351-60
DOI 10.1001/jamapediatrics.2013.4647, PubMed 24493300 -
Evaluation of elastic bands for lower extremity resistance training in adults with and without musculo-skeletal pain
Scand J Med Sci Sports, 24 (5), e353-9
DOI 10.1111/sms.12187, PubMed 25138624 -
European Confederation of Medical Mycology (ECMM) epidemiological survey on invasive infections due to Fusarium species in Europe
Eur J Clin Microbiol Infect Dis, 33 (9), 1623-30
DOI 10.1007/s10096-014-2111-1, PubMed 24791951 -
Viral infection in placenta relevant cells--a morphological and immunohistochemical cell culture study
APMIS, 123 (1), 60-4
DOI 10.1111/apm.12307, PubMed 25244625 -
Reactivation of occult herpes simplex meningoencephalitis after temporal lobe resection for refractory epilepsy--a case report
Seizure, 23 (4), 321-3
DOI 10.1016/j.seizure.2014.01.010, PubMed 24521759 -
Addressing RNA integrity to determine the impact of mitochondrial DNA mutations on brain mitochondrial function with age
PLoS One, 9 (5), e96940
DOI 10.1371/journal.pone.0096940, PubMed 24819950 -
Molecular basis of calpain cleavage and inactivation of the sodium-calcium exchanger 1 in heart failure
J Biol Chem, 289 (49), 33984-98
DOI 10.1074/jbc.M114.602581, PubMed 25336645 -
Human OXR1 maintains mitochondrial DNA integrity and counteracts hydrogen peroxide-induced oxidative stress by regulating antioxidant pathways involving p21
Free Radic Biol Med, 77, 41-8
DOI 10.1016/j.freeradbiomed.2014.09.003, PubMed 25236744 -
Time to first consultation, diagnosis and treatment of TB among patients attending a referral hospital in Northwest, Ethiopia
BMC Infect Dis, 14, 19
DOI 10.1186/1471-2334-14-19, PubMed 24410927 -
Tuberculosis management time: an alternative parameter for measuring the tuberculosis infectious pool
Trop Med Int Health, 19 (3), 313-320
DOI 10.1111/tmi.12246, PubMed 24393123 -
Uncovering the mechanism of trapping and cell orientation during Neisseria gonorrhoeae twitching motility
Biophys J, 107 (7), 1523-31
DOI 10.1016/j.bpj.2014.07.061, PubMed 25296304 -
Protozoan ALKBH8 oxygenases display both DNA repair and tRNA modification activities
PLoS One, 9 (6), e98729
DOI 10.1371/journal.pone.0098729, PubMed 24914785 -
Early-onset Crohn's disease and autoimmunity associated with a variant in CTLA-4
Gut, 64 (12), 1889-97
DOI 10.1136/gutjnl-2014-308541, PubMed 25367873 -
Ginsenoside Rd attenuates tau protein phosphorylation via the PI3K/AKT/GSK-3β pathway after transient forebrain ischemia
Neurochem Res, 39 (7), 1363-73
DOI 10.1007/s11064-014-1321-3, PubMed 24792734 -
Cockayne Syndrome group B protein stimulates NEIL2 DNA glycosylase activity
Mech Ageing Dev, 135, 1-14
DOI 10.1016/j.mad.2013.12.008, PubMed 24406253
Publications 2013
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SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements
Mol Biol Cell, 25 (4), 532-47
DOI 10.1091/mbc.E13-05-0286, PubMed 24356447 -
Emerging roles of the nucleolus in regulating the DNA damage response: the noncanonical DNA repair enzyme APE1/Ref-1 as a paradigmatical example
Antioxid Redox Signal, 20 (4), 621-39
DOI 10.1089/ars.2013.5491, PubMed 23879289 -
A new family of proteins related to the HEAT-like repeat DNA glycosylases with affinity for branched DNA structures
J Struct Biol, 183 (1), 66-75
DOI 10.1016/j.jsb.2013.04.007, PubMed 23623903 -
Novel Deletion Mutation Identified in a Patient with Late-Onset Combined Methylmalonic Acidemia and Homocystinuria, cblC Type
JIMD Rep, 11, 79-85
DOI 10.1007/8904_2013_225, PubMed 23580368 -
Tiling array study of MNNG treated Escherichia coli reveals a widespread transcriptional response
Sci Rep, 3, 3053
DOI 10.1038/srep03053, PubMed 24157950 -
Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4
Hepatology, 58 (3), 1074-83
DOI 10.1002/hep.25977, PubMed 22821403 -
Interlaboratory variability of Caspofungin MICs for Candida spp. Using CLSI and EUCAST methods: should the clinical laboratory be testing this agent?
Antimicrob Agents Chemother, 57 (12), 5836-42
DOI 10.1128/AAC.01519-13, PubMed 24018263 -
Lactobacillus plantarum WCFS1 O-linked protein glycosylation: an extended spectrum of target proteins and modification sites detected by mass spectrometry
Glycobiology, 23 (12), 1439-51
DOI 10.1093/glycob/cwt071, PubMed 24000282 -
Dialects of the DNA uptake sequence in Neisseriaceae
PLoS Genet, 9 (4), e1003458
DOI 10.1371/journal.pgen.1003458, PubMed 23637627 -
Tzfp represses the androgen receptor in mouse testis
PLoS One, 8 (4), e62314
DOI 10.1371/journal.pone.0062314, PubMed 23634227 -
Accelerated clinical course of prion disease in mice compromised in repair of oxidative DNA damage
Free Radic Biol Med, 68, 1-7
DOI 10.1016/j.freeradbiomed.2013.11.013, PubMed 24296244 -
Oxidative stress causes DNA triplet expansion in Huntington's disease mouse embryonic stem cells
Stem Cell Res, 11 (3), 1264-71
DOI 10.1016/j.scr.2013.08.010, PubMed 24041806 -
DNA repair mechanisms in Huntington's disease
Mol Neurobiol, 47 (3), 1093-102
DOI 10.1007/s12035-013-8409-7, PubMed 23361256 -
Base excision repair
Cold Spring Harb Perspect Biol, 5 (4), a012583
DOI 10.1101/cshperspect.a012583, PubMed 23545420 -
Human NEIL3 is mainly a monofunctional DNA glycosylase removing spiroimindiohydantoin and guanidinohydantoin
DNA Repair (Amst), 12 (12), 1159-64
DOI 10.1016/j.dnarep.2013.04.026, PubMed 23755964 -
RhoA regulation of cardiomyocyte differentiation
ScientificWorldJournal, 2013, 491546
DOI 10.1155/2013/491546, PubMed 23935420 -
ALKBH4-dependent demethylation of actin regulates actomyosin dynamics
Nat Commun, 4, 1832
DOI 10.1038/ncomms2863, PubMed 23673617 -
Transient OGG1, APE1, PARP1 and Polβ expression in an Alzheimer's disease mouse model
Mech Ageing Dev, 134 (10), 467-77
DOI 10.1016/j.mad.2013.09.002, PubMed 24121118 -
Rat macrophage C-type lectin is an activating receptor expressed by phagocytic cells
PLoS One, 8 (2), e57406
DOI 10.1371/journal.pone.0057406, PubMed 23468983 -
SAPA tool: finding protein regions by combination of amino acid composition, scaled profiles, patterns and rules
Bioinformatics, 29 (19), 2496-7
DOI 10.1093/bioinformatics/btt411, PubMed 23868956 -
Histone acetyltransferase PCAF is required for Hedgehog-Gli-dependent transcription and cancer cell proliferation
Cancer Res, 73 (20), 6323-33
DOI 10.1158/0008-5472.CAN-12-4660, PubMed 23943798 -
Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases
Antioxid Redox Signal, 20 (2), 217-35
DOI 10.1089/ars.2012.5051, PubMed 23641861 -
The glia doctrine: addressing the role of glial cells in healthy brain ageing
Mech Ageing Dev, 134 (10), 449-59
DOI 10.1016/j.mad.2013.10.001, PubMed 24141107 -
Large IncHI2-plasmids encode extended-spectrum β-lactamases (ESBLs) in Enterobacter spp. bloodstream isolates, and support ESBL-transfer to Escherichia coli
Clin Microbiol Infect, 19 (11), E516-8
DOI 10.1111/1469-0691.12274, PubMed 23800169 -
Role of the unstructured N-terminal domain of the hAPE1 (human apurinic/apyrimidinic endonuclease 1) in the modulation of its interaction with nucleic acids and NPM1 (nucleophosmin)
Biochem J, 452 (3), 545-57
DOI 10.1042/BJ20121277, PubMed 23544830 -
DNA damage response, bioenergetics, and neurological disease: the challenge of maintaining brain health in an aging human population
Mech Ageing Dev, 134 (10), 427-33
DOI 10.1016/j.mad.2013.05.001, PubMed 23665461 -
Virologic suppression measured by a cytomegalovirus (CMV) DNA test calibrated to the World Health Organization international standard is predictive of CMV disease resolution in transplant recipients
Clin Infect Dis, 56 (11), 1546-53
DOI 10.1093/cid/cit096, PubMed 23418272 -
Characterization of cytomegalovirus disease in solid organ transplant recipients by markers of inflammation in plasma
PLoS One, 8 (4), e60767
DOI 10.1371/journal.pone.0060767, PubMed 23593305 -
Loss of Neil3, the major DNA glycosylase activity for removal of hydantoins in single stranded DNA, reduces cellular proliferation and sensitizes cells to genotoxic stress
Biochim Biophys Acta, 1833 (5), 1157-64
DOI 10.1016/j.bbamcr.2012.12.024, PubMed 23305905 -
Structural basis of DNA loop recognition by endonuclease V
Structure, 21 (2), 257-65
DOI 10.1016/j.str.2012.12.007, PubMed 23313664 -
The impact of early cytomegalovirus infection after kidney transplantation on long-term graft and patient survival
Clin Transplant, 28 (1), 120-6
DOI 10.1111/ctr.12288, PubMed 24351078 -
Deletion of mouse Alkbh7 leads to obesity
J Mol Cell Biol, 5 (3), 194-203
DOI 10.1093/jmcb/mjt012, PubMed 23572141 -
[Diagnosis of chronic hepatitis B infection]
Tidsskr Nor Laegeforen, 133 (16), 1717-21
DOI 10.4045/tidsskr.12.1206, PubMed 24005708 -
Evolutionary paths of the cAMP-dependent protein kinase (PKA) catalytic subunits
PLoS One, 8 (4), e60935
DOI 10.1371/journal.pone.0060935, PubMed 23593352 -
Virologic and immunologic response to cART by HIV-1 subtype in the CASCADE collaboration
PLoS One, 8 (7), e71174
DOI 10.1371/journal.pone.0071174, PubMed 23936260 -
Plasma lipopolysaccharide is closely associated with glycemic control and abdominal obesity: evidence from bariatric surgery
Diabetes Care, 36 (11), 3627-32
DOI 10.2337/dc13-0451, PubMed 23835694 -
Secreted Wnt antagonists during eradication of cytomegalovirus infection in solid organ transplant recipients
Am J Transplant, 14 (1), 210-5
DOI 10.1111/ajt.12506, PubMed 24224707 -
Primary toxoplasmosis with critical illness and multi-organ failure in an immunocompetent young man
Scand J Infect Dis, 46 (1), 58-62
DOI 10.3109/00365548.2013.813065, PubMed 23902584 -
Endonuclease V cleaves at inosines in RNA
Nat Commun, 4, 2271
DOI 10.1038/ncomms3271, PubMed 23912683 -
DNA metabolism in mycobacterial pathogenesis
Curr Top Microbiol Immunol, 374, 27-51
DOI 10.1007/82_2013_328, PubMed 23633106 -
Single transmembrane peptide DinQ modulates membrane-dependent activities
PLoS Genet, 9 (2), e1003260
DOI 10.1371/journal.pgen.1003260, PubMed 23408903 -
Age-related differences in symptoms, diagnosis and prognosis of bacteremia
BMC Infect Dis, 13, 346
DOI 10.1186/1471-2334-13-346, PubMed 23883345 -
Transcriptome profiling of the newborn mouse lung after hypoxia and reoxygenation: hyperoxic reoxygenation affects mTOR signaling pathway, DNA repair, and JNK-pathway regulation
Pediatr Res, 74 (5), 536-44
DOI 10.1038/pr.2013.140, PubMed 23999071 -
Transcriptome profiling of the newborn mouse brain after hypoxia-reoxygenation: hyperoxic reoxygenation induces inflammatory and energy failure responsive genes
Pediatr Res, 75 (4), 517-26
DOI 10.1038/pr.2013.249, PubMed 24375083 -
Effects of conserved residues and naturally occurring mutations on Mycobacterium tuberculosis RecG helicase activity
Microbiology (Reading), 160 (Pt 1), 217-227
DOI 10.1099/mic.0.072140-0, PubMed 24169816 -
Ginsenoside Rd promotes glutamate clearance by up-regulating glial glutamate transporter GLT-1 via PI3K/AKT and ERK1/2 pathways
Front Pharmacol, 4, 152
DOI 10.3389/fphar.2013.00152, PubMed 24376419 -
Sprouts of RNA epigenetics: the discovery of mammalian RNA demethylases
RNA Biol, 10 (6), 915-8
DOI 10.4161/rna.24711, PubMed 23619745 -
TORC1 inhibits GSK3-mediated Elo2 phosphorylation to regulate very long chain fatty acid synthesis and autophagy
Cell Rep, 5 (4), 1036-46
DOI 10.1016/j.celrep.2013.10.024, PubMed 24239358
Publications 2012
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Antibiotic resistance in hospitals: a ward-specific random effect model in a low antibiotic consumption environment
Stat Med, 32 (8), 1407-18
DOI 10.1002/sim.5636, PubMed 23027651 -
Restriction and sequence alterations affect DNA uptake sequence-dependent transformation in Neisseria meningitidis
PLoS One, 7 (7), e39742
DOI 10.1371/journal.pone.0039742, PubMed 22768309 -
Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor
Nat Commun, 3, 610
DOI 10.1038/ncomms1607, PubMed 22215085 -
Enzymatic activities and DNA substrate specificity of Mycobacterium tuberculosis DNA helicase XPB
PLoS One, 7 (5), e36960
DOI 10.1371/journal.pone.0036960, PubMed 22615856 -
Hereditary tyrosinaemia type I in Norway: incidence and three novel small deletions in the fumarylacetoacetase gene
Scand J Clin Lab Invest, 72 (5), 369-73
DOI 10.3109/00365513.2012.676210, PubMed 22554029 -
Fumarylacetoacetate inhibits the initial step of the base excision repair pathway: implication for the pathogenesis of tyrosinemia type I
J Inherit Metab Dis, 36 (5), 773-8
DOI 10.1007/s10545-012-9556-0, PubMed 23138988 -
Molecular characterization of methicillin-sensitive Staphylococcus aureus isolates from bacteremic patients in a Norwegian University Hospital
J Clin Microbiol, 51 (1), 345-7
DOI 10.1128/JCM.02571-12, PubMed 23135934 -
Cytomegalovirus viremia in dried blood spots is associated with an increased risk of death in HIV-infected patients: a cohort study from rural Tanzania
Int J Infect Dis, 16 (12), e879-85
DOI 10.1016/j.ijid.2012.08.003, PubMed 23031419 -
DNA repair is indispensable for survival after acute inflammation
J Clin Invest, 122 (7), 2680-9
DOI 10.1172/JCI63338, PubMed 22684101 -
Cdc28 kinase activity regulates the basal transcription machinery at a subset of genes
Proc Natl Acad Sci U S A, 109 (26), 10450-5
DOI 10.1073/pnas.1200067109, PubMed 22689984 -
The cell cycle rallies the transcription cycle: Cdc28/Cdk1 is a cell cycle-regulated transcriptional CDK
Transcription, 4 (1), 3-6
DOI 10.4161/trns.22456, PubMed 23131667 -
Sculpting of DNA at abasic sites by DNA glycosylase homolog mag2
Structure, 21 (1), 154-166
DOI 10.1016/j.str.2012.11.004, PubMed 23245849 -
Enhanced levels of CCL19 in patients with advanced acquired immune deficiency syndrome (AIDS)
Clin Exp Immunol, 167 (3), 492-8
DOI 10.1111/j.1365-2249.2011.04524.x, PubMed 22288592 -
Phylogenetic analysis of human immunodeficiency virus type 1 subtype C env gp120 sequences among four drug-naive families following subsequent heterosexual and vertical transmissions
AIDS Res Hum Retroviruses, 28 (8), 885-93
DOI 10.1089/AID.2011.0217, PubMed 22206228 -
Chemical genetics: budding yeast as a platform for drug discovery and mapping of genetic pathways
Molecules, 17 (8), 9258-73
DOI 10.3390/molecules17089258, PubMed 22858845 -
What makes the engine hum: Rad6, a cell cycle supercharger
Cell Cycle, 11 (2), 249-52
DOI 10.4161/cc.11.2.19023, PubMed 22214660 -
The human homolog of Escherichia coli endonuclease V is a nucleolar protein with affinity for branched DNA structures
PLoS One, 7 (11), e47466
DOI 10.1371/journal.pone.0047466, PubMed 23139746 -
Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci
J Hepatol, 57 (2), 366-75
DOI 10.1016/j.jhep.2012.03.031, PubMed 22521342 -
Multilocus sequence typing of serial Candida albicans isolates from children with cancer, children with cystic fibrosis and healthy controls
Med Mycol, 50 (6), 619-26
DOI 10.3109/13693786.2012.675088, PubMed 22524637 -
The role of properdin in zymosan- and Escherichia coli-induced complement activation
J Immunol, 189 (5), 2606-13
DOI 10.4049/jimmunol.1200269, PubMed 22851705 -
Elevated troponin I and NT-proBNP at the time of transplantation may predict a major adverse cardiac event in the early postoperative period after renal transplantation
Transplantation, 94 (2), e15-6
DOI 10.1097/TP.0b013e31825b7633, PubMed 22820562 -
Structure and function of the human sperm-specific isoform of protein kinase A (PKA) catalytic subunit Cα2
J Struct Biol, 178 (3), 300-10
DOI 10.1016/j.jsb.2012.03.013, PubMed 22504716 -
Appropriate time for test-of-cure when diagnosing gonorrhoea with a nucleic acid amplification test
Acta Derm Venereol, 92 (3), 316-9
DOI 10.2340/00015555-1275, PubMed 22286973 -
Does occupational lifting and carrying among female health care workers contribute to an escalation of pain-day frequency?
Eur J Pain, 17 (2), 290-6
DOI 10.1002/j.1532-2149.2012.00175.x, PubMed 22641396 -
Silver nanoparticles induce premutagenic DNA oxidation that can be prevented by phytochemicals from Gentiana asclepiadea
Mutagenesis, 27 (6), 759-69
DOI 10.1093/mutage/ges046, PubMed 22940646 -
The human base excision repair enzyme SMUG1 directly interacts with DKC1 and contributes to RNA quality control
Mol Cell, 49 (2), 339-45
DOI 10.1016/j.molcel.2012.11.010, PubMed 23246433 -
Kinetics of endogenous mouse FEN1 in base excision repair
Nucleic Acids Res, 40 (18), 9044-59
DOI 10.1093/nar/gks673, PubMed 22810208 -
The Schizosaccharomyces pombe AlkB homolog Abh1 exhibits AP lyase activity but no demethylase activity
DNA Repair (Amst), 11 (5), 453-62
DOI 10.1016/j.dnarep.2012.01.014, PubMed 22365419 -
Unchanged antibiotic susceptibility in Escherichia coli and Pseudomonas aeruginosa after long-term in vitro exposure to antineoplastic drugs
Chemotherapy, 58 (2), 118-22
DOI 10.1159/000337058, PubMed 22507969 -
Resistance rates of metronidazole and other antibacterials in Helicobacter pylori from previously untreated patients in Norway
APMIS, 121 (4), 353-8
DOI 10.1111/apm.12009, PubMed 23083455 -
The arsenic-based cure of acute promyelocytic leukemia promotes cytoplasmic sequestration of PML and PML/RARA through inhibition of PML body recycling
Blood, 120 (4), 847-57
DOI 10.1182/blood-2011-10-388496, PubMed 22692509 -
Helicobacter pylori resistance to antibiotics in Europe and its relationship to antibiotic consumption
Gut, 62 (1), 34-42
DOI 10.1136/gutjnl-2012-302254, PubMed 22580412 -
The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage
Nucleic Acids Res, 40 (14), 6620-31
DOI 10.1093/nar/gks327, PubMed 22532610 -
Neil1 is a genetic modifier of somatic and germline CAG trinucleotide repeat instability in R6/1 mice
Hum Mol Genet, 21 (22), 4939-47
DOI 10.1093/hmg/dds337, PubMed 22914735 -
Vacuum extraction: development and test of a procedure-specific rating scale
Acta Obstet Gynecol Scand, 91 (12), 1453-9
DOI 10.1111/j.1600-0412.2012.01526.x, PubMed 22881021 -
Release from quiescence stimulates the expression of human NEIL3 under the control of the Ras dependent ERK-MAP kinase pathway
DNA Repair (Amst), 11 (4), 401-9
DOI 10.1016/j.dnarep.2012.01.007, PubMed 22365498 -
Alkbh1 and Tzfp repress a non-repeat piRNA cluster in pachytene spermatocytes
Nucleic Acids Res, 40 (21), 10950-63
DOI 10.1093/nar/gks839, PubMed 22965116 -
ALKBH1 is a histone H2A dioxygenase involved in neural differentiation
Stem Cells, 30 (12), 2672-82
DOI 10.1002/stem.1228, PubMed 22961808 -
Hallmarks of processivity in glycoside hydrolases from crystallographic and computational studies of the Serratia marcescens chitinases
J Biol Chem, 287 (43), 36322-30
DOI 10.1074/jbc.M112.402149, PubMed 22952223 -
Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae
Mol Biosyst, 8 (3), 796-803
DOI 10.1039/c2mb05356j, PubMed 22218487 -
Infectious encephalitis: a description of a Norwegian cohort
Scand J Infect Dis, 45 (3), 179-85
DOI 10.3109/00365548.2012.719634, PubMed 23113672 -
The chromatin remodeling factor SMARCB1 forms a complex with human cytomegalovirus proteins UL114 and UL44
PLoS One, 7 (3), e34119
DOI 10.1371/journal.pone.0034119, PubMed 22479537 -
Hippocampal adult neurogenesis is maintained by Neil3-dependent repair of oxidative DNA lesions in neural progenitor cells
Cell Rep, 2 (3), 503-10
DOI 10.1016/j.celrep.2012.08.008, PubMed 22959434 -
[Pregnancy following bariatric surgery requires special attention]
Ugeskr Laeger, 174 (16), 1076-9
PubMed 22510546 -
Gut bacterial profile in patients newly diagnosed with treatment-naïve Crohn's disease
Clin Exp Gastroenterol, 5, 173-86
DOI 10.2147/CEG.S33858, PubMed 23049264 -
Pull-down of 5-hydroxymethylcytosine DNA using JBP1-coated magnetic beads
Nat Protoc, 7 (2), 340-50
DOI 10.1038/nprot.2011.443, PubMed 22281869 -
Does work-site physical activity improve self-reported psychosocial workplace factors and job satisfaction? A randomized controlled intervention study
Int Arch Occup Environ Health, 86 (8), 861-4
DOI 10.1007/s00420-012-0823-z, PubMed 23064844 -
Treatment of cytomegalovirus disease in solid organ transplant recipients: markers of inflammation as predictors of outcome
Transplantation, 94 (10), 1060-5
DOI 10.1097/TP.0b013e31826c39de, PubMed 23104251 -
Systemic biomarkers of inflammation and haemostasis in patients with chronic necrotizing pulmonary aspergillosis
BMC Infect Dis, 12, 144
DOI 10.1186/1471-2334-12-144, PubMed 22731696 -
Oxygenation of the newborn: a molecular approach
Neonatology, 101 (4), 315-25
DOI 10.1159/000337345, PubMed 22940621 -
Analysis of evolutionary patterns of genes in Campylobacter jejuni and C. coli
Microb Inform Exp, 2 (1), 8
DOI 10.1186/2042-5783-2-8, PubMed 22929701 -
Identification and characterization of novel mutations in the human gene encoding the catalytic subunit Calpha of protein kinase A (PKA)
PLoS One, 7 (4), e34838
DOI 10.1371/journal.pone.0034838, PubMed 22514673 -
Impact of HIV-1 subtype on CD4 count at HIV seroconversion, rate of decline, and viral load set point in European seroconverter cohorts
Clin Infect Dis, 56 (6), 888-97
DOI 10.1093/cid/cis1000, PubMed 23223594 -
Neisseria gonorrhoeae strain with high-level resistance to spectinomycin due to a novel resistance mechanism (mutated ribosomal protein S5) verified in Norway
Antimicrob Agents Chemother, 57 (2), 1057-61
DOI 10.1128/AAC.01775-12, PubMed 23183436 -
Biochemical mapping of human NEIL1 DNA glycosylase and AP lyase activities
DNA Repair (Amst), 11 (9), 766-73
DOI 10.1016/j.dnarep.2012.07.002, PubMed 22858590 -
Helicobacter pylori infection and severe hyperemesis gravidarum among immigrant women in Norway: a case-control study
Eur J Obstet Gynecol Reprod Biol, 167 (1), 41-6
DOI 10.1016/j.ejogrb.2012.11.007, PubMed 23273662 -
[Obese pregnant women and complications in relation to pregnancy and birth]
Ugeskr Laeger, 174 (16), 1079-82
PubMed 22510547 -
Mycobacterium tuberculosis RecG binds and unwinds model DNA substrates with a preference for Holliday junctions
Microbiology (Reading), 158 (Pt 8), 1982-1993
DOI 10.1099/mic.0.058693-0, PubMed 22628485 -
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility
Mol Cell, 49 (1), 18-29
DOI 10.1016/j.molcel.2012.10.015, PubMed 23177736 -
Molecular characterisation of methicillin-sensitive Staphylococcus aureus from deep surgical site infections in orthopaedic patients
Eur J Clin Microbiol Infect Dis, 31 (8), 1999-2004
DOI 10.1007/s10096-011-1532-3, PubMed 22258425
Publications 2011
-
The molecular structure of tris-2,2,6,6-tetramethyl-heptane-3,5-dione aluminium: gas-phase electron diffraction, quantum chemical calculations and X-ray crystallography
Struct. Chem., 22 (2), 393-399
DOI 10.1007/s11224-010-9729-0 -
Structure-function relationships of the competence lipoprotein ComL and SSB in meningococcal transformation
Microbiology (Reading), 157 (Pt 5), 1329-1342
DOI 10.1099/mic.0.046896-0, PubMed 21330432 -
Infectious immune status in an obstetric population of Pakistani immigrants in Norway
Scand J Public Health, 39 (5), 464-70
DOI 10.1177/1403494811399653, PubMed 21339369 -
Hospitalised patients with suspected 2009 H1N1 influenza A in a hospital in Norway, July - December 2009
BMC Infect Dis, 11, 75
DOI 10.1186/1471-2334-11-75, PubMed 21435254 -
Separation-of-function mutants unravel the dual-reaction mode of human 8-oxoguanine DNA glycosylase
Structure, 19 (1), 117-27
DOI 10.1016/j.str.2010.09.023, PubMed 21220122 -
Human Immunodeficiency Virus (HIV) types Western blot (WB) band profiles as potential surrogate markers of HIV disease progression and predictors of vertical transmission in a cohort of infected but antiretroviral therapy naïve pregnant women in Harare, Zimbabwe
BMC Infect Dis, 11, 7
DOI 10.1186/1471-2334-11-7, PubMed 21211021 -
Detection of changes in gene regulatory patterns, elicited by perturbations of the Hsp90 molecular chaperone complex, by visualizing multiple experiments with an animation
BioData Min, 4 (1), 15
DOI 10.1186/1756-0381-4-15, PubMed 21672238 -
Colonization by Candida in children with cancer, children with cystic fibrosis, and healthy controls
Clin Microbiol Infect, 17 (12), 1875-81
DOI 10.1111/j.1469-0691.2011.03528.x, PubMed 21745258 -
Evidence that compromised K+ spatial buffering contributes to the epileptogenic effect of mutations in the human Kir4.1 gene (KCNJ10)
Glia, 59 (11), 1635-42
DOI 10.1002/glia.21205, PubMed 21748805 -
Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood-brain water uptake and confers barrier function on perivascular astrocyte endfeet
Proc Natl Acad Sci U S A, 108 (43), 17815-20
DOI 10.1073/pnas.1110655108, PubMed 21990350 -
Lack of the DNA glycosylases MYH and OGG1 in the cancer prone double mutant mouse does not increase mitochondrial DNA mutagenesis
DNA Repair (Amst), 11 (3), 278-85
DOI 10.1016/j.dnarep.2011.12.001, PubMed 22209780 -
DNA alkylation lesions and their repair in human cells: modification of the comet assay with 3-methyladenine DNA glycosylase (AlkD)
Toxicol Lett, 208 (1), 76-81
DOI 10.1016/j.toxlet.2011.10.005, PubMed 22019460 -
Exogenous pyruvate accelerates glycolysis and promotes capacitation in human spermatozoa
Hum Reprod, 26 (12), 3249-63
DOI 10.1093/humrep/der317, PubMed 21946930 -
Two Norwegian patients with melioidosis presenting with bacteraemia and splenic and prostatic abscesses
J Travel Med, 18 (6), 418-21
DOI 10.1111/j.1708-8305.2011.00550.x, PubMed 22017720 -
Phenotypic and genotypic properties of Neisseria gonorrhoeae isolates in Norway in 2009: antimicrobial resistance warrants an immediate change in national management guidelines
Eur J Clin Microbiol Infect Dis, 31 (6), 1181-6
DOI 10.1007/s10096-011-1426-4, PubMed 21960034 -
Role of the C-terminal domain of PCSK9 in degradation of the LDL receptors
J Lipid Res, 52 (10), 1787-94
DOI 10.1194/jlr.M018093, PubMed 21771976 -
Removal of acidic residues of the prodomain of PCSK9 increases its activity towards the LDL receptor
Biochem Biophys Res Commun, 406 (2), 234-8
DOI 10.1016/j.bbrc.2011.02.023, PubMed 21324305 -
Myostatin expression during human muscle hypertrophy and subsequent atrophy: increased myostatin with detraining
Scand J Med Sci Sports, 21 (2), 215-23
DOI 10.1111/j.1600-0838.2009.01044.x, PubMed 19903317 -
Is the brain water channel aquaporin-4 a pathogenetic factor in idiopathic intracranial hypertension? Results from a combined clinical and genetic study in a Norwegian cohort
Acta Ophthalmol, 91 (1), 88-91
DOI 10.1111/j.1755-3768.2011.02231.x, PubMed 21914143 -
Schizosaccharomyces pombe Ofd2 is a nuclear 2-oxoglutarate and iron dependent dioxygenase interacting with histones
PLoS One, 6 (9), e25188
DOI 10.1371/journal.pone.0025188, PubMed 21949882 -
Delayed-type hypersensitivity responses to HIV Gag p24 relate to clinical outcome after peptide-based therapeutic immunization for chronic HIV infection
APMIS, 120 (3), 204-9
DOI 10.1111/j.1600-0463.2011.02843.x, PubMed 22339677 -
Clinical aspects of a nationwide epidemic of severe haemolytic uremic syndrome (HUS) in children
Scand J Trauma Resusc Emerg Med, 19, 44
DOI 10.1186/1757-7241-19-44, PubMed 21798000 -
Human cytomegalovirus infection increases mitochondrial biogenesis
Mitochondrion, 11 (6), 935-45
DOI 10.1016/j.mito.2011.08.008, PubMed 21907833 -
Mitochondrial DNA toxicity compromises mitochondrial dynamics and induces hippocampal antioxidant defenses
DNA Repair (Amst), 10 (6), 639-53
DOI 10.1016/j.dnarep.2011.04.011, PubMed 21550321 -
Modeling the impact of mitochondrial DNA damage in forebrain neurons and beyond
Mech Ageing Dev, 132 (8-9), 424-8
DOI 10.1016/j.mad.2011.02.006, PubMed 21354441 -
DNA base excision repair gene polymorphisms modulate human cognitive performance and decline during normal life span
Mech Ageing Dev, 132 (8-9), 449-58
DOI 10.1016/j.mad.2011.08.002, PubMed 21884718 -
Detection and characterisation of SCCmec remnants in multiresistant methicillin-susceptible Staphylococcus aureus causing a clonal outbreak in a Swedish county
Eur J Clin Microbiol Infect Dis, 31 (2), 141-7
DOI 10.1007/s10096-011-1286-y, PubMed 21590357 -
The clinical utility of whole blood versus plasma cytomegalovirus viral load assays for monitoring therapeutic response
Transplantation, 91 (2), 231-6
DOI 10.1097/TP.0b013e3181ff8719, PubMed 21048530 -
Analysis and clinical correlation of genetic variation in cytomegalovirus
Transpl Infect Dis, 14 (2), 132-40
DOI 10.1111/j.1399-3062.2011.00685.x, PubMed 22093996 -
Uracil-DNA glycosylase of Thermoplasma acidophilum directs long-patch base excision repair, which is promoted by deoxynucleoside triphosphates and ATP/ADP, into short-patch repair
J Bacteriol, 193 (17), 4495-508
DOI 10.1128/JB.00233-11, PubMed 21665970 -
Incidence and outcomes of ganciclovir-resistant cytomegalovirus infections in 1244 kidney transplant recipients
Transplantation, 92 (2), 217-23
DOI 10.1097/TP.0b013e31821fad25, PubMed 21685829 -
AP endonuclease independent repair of abasic sites in Schizosaccharomyces pombe
Nucleic Acids Res, 40 (5), 2000-9
DOI 10.1093/nar/gkr933, PubMed 22084197 -
Diphtheria outbreak in Norway: lessons learned
Scand J Infect Dis, 43 (11-12), 986-9
DOI 10.3109/00365548.2011.600326, PubMed 21867473 -
Considered "negative" for MAP, these results would be very "positive" for tuberculoid leprosy Reply
J. Crohns Colitis, 5 (4), 374
DOI 10.1016/j.crohns.2011.04.007 -
A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA
Nucleic Acids Res, 39 (8), e55
DOI 10.1093/nar/gkr051, PubMed 21300643 -
The presence of 5-hydroxymethylcytosine at the gene promoter and not in the gene body negatively regulates gene expression
Biochem Biophys Res Commun, 411 (1), 40-3
DOI 10.1016/j.bbrc.2011.06.077, PubMed 21703242 -
Faster Smith-Waterman database searches with inter-sequence SIMD parallelisation
BMC Bioinformatics, 12, 221
DOI 10.1186/1471-2105-12-221, PubMed 21631914 -
Molecular characterization of VIM-producing Klebsiella pneumoniae from Scandinavia reveals genetic relatedness with international clonal complexes encoding transferable multidrug resistance
Clin Microbiol Infect, 17 (12), 1811-6
DOI 10.1111/j.1469-0691.2011.03532.x, PubMed 21595797 -
Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia
Proc Natl Acad Sci U S A, 108 (46), 18802-7
DOI 10.1073/pnas.1106880108, PubMed 22065741 -
Zygomycosis in Europe: analysis of 230 cases accrued by the registry of the European Confederation of Medical Mycology (ECMM) Working Group on Zygomycosis between 2005 and 2007
Clin Microbiol Infect, 17 (12), 1859-67
DOI 10.1111/j.1469-0691.2010.03456.x, PubMed 21199154 -
A 15-month-old girl with fever and pancytopenia
Tidsskr Nor Laegeforen, 131 (24), 2482-6
DOI 10.4045/tidsskr.11.0387, PubMed 22170136 -
Characterization and functional analysis of the 5'-flanking promoter region of the mouse Tcf3 gene
Mol Cell Biochem, 360 (1-2), 289-99
DOI 10.1007/s11010-011-1068-y, PubMed 21935611 -
A novel synthetic smoothened antagonist transiently inhibits pancreatic adenocarcinoma xenografts in a mouse model
PLoS One, 6 (6), e19904
DOI 10.1371/journal.pone.0019904, PubMed 21698280 -
X-linked Angelman-like syndrome caused by Slc9a6 knockout in mice exhibits evidence of endosomal-lysosomal dysfunction
Brain, 134 (Pt 11), 3369-83
DOI 10.1093/brain/awr250, PubMed 21964919 -
Interaction between the ligand-binding domain of the LDL receptor and the C-terminal domain of PCSK9 is required for PCSK9 to remain bound to the LDL receptor during endosomal acidification
Hum Mol Genet, 21 (6), 1402-9
DOI 10.1093/hmg/ddr578, PubMed 22156580 -
Kiss and run - phosphoglycerol modifications of N. Meningitidis pili mediate detachment
Front Microbiol, 2, 82
DOI 10.3389/fmicb.2011.00082, PubMed 21747798 -
ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA
Nat Commun, 2, 172
DOI 10.1038/ncomms1173, PubMed 21285950 -
Pherotypes of pneumococcal strains co-existing in healthy children
Infect Genet Evol, 11 (7), 1703-8
DOI 10.1016/j.meegid.2011.07.003, PubMed 21763465 -
Characterization of the chitinolytic machinery of Enterococcus faecalis V583 and high-resolution structure of its oxidative CBM33 enzyme
J Mol Biol, 416 (2), 239-54
DOI 10.1016/j.jmb.2011.12.033, PubMed 22210154 -
Mitochondrial DNA damage level determines neural stem cell differentiation fate
J Neurosci, 31 (26), 9746-51
DOI 10.1523/JNEUROSCI.0852-11.2011, PubMed 21715639 -
Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth
Cancer Res, 71 (1), 197-205
DOI 10.1158/0008-5472.CAN-10-1282, PubMed 21199802 -
The ada operon of Mycobacterium tuberculosis encodes two DNA methyltransferases for inducible repair of DNA alkylation damage
DNA Repair (Amst), 10 (6), 595-602
DOI 10.1016/j.dnarep.2011.03.007, PubMed 21570366 -
A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression
Proc Natl Acad Sci U S A, 108 (46), 18748-53
DOI 10.1073/pnas.1115885108, PubMed 22042866 -
Mycoplasma contamination revisited: mesenchymal stromal cells harboring Mycoplasma hyorhinis potently inhibit lymphocyte proliferation in vitro
PLoS One, 6 (1), e16005
DOI 10.1371/journal.pone.0016005, PubMed 21264307
Publications 2010
-
Failure of dry mist of hydrogen peroxide 5% to kill Mycobacterium tuberculosis
J Hosp Infect, 76 (1), 80-3
DOI 10.1016/j.jhin.2010.03.013, PubMed 20638944 -
Rapid MRSA test in exposed persons: costs and savings in hospitals
J Infect, 60 (4), 293-9
DOI 10.1016/j.jinf.2010.01.008, PubMed 20122959 -
Caenorhabditis elegans NDX-4 is a MutT-type enzyme that contributes to genomic stability
DNA Repair (Amst), 10 (2), 176-87
DOI 10.1016/j.dnarep.2010.10.009, PubMed 21111690 -
Effects of the intensity of immunosuppressive therapy on outcome of treatment for CMV disease in organ transplant recipients
Am J Transplant, 10 (8), 1881-8
DOI 10.1111/j.1600-6143.2010.03114.x, PubMed 20486914 -
Sexually transmitted infections among Pakistani pregnant women and their husbands in Norway
Int J Womens Health, 2, 303-9
DOI 10.2147/IJWH.S13018, PubMed 21151677 -
Analysis of intra-genomic GC content homogeneity within prokaryotes
BMC Genomics, 11, 464
DOI 10.1186/1471-2164-11-464, PubMed 20691090 -
Drug resistance is widespread among children who receive long-term antiretroviral treatment at a rural Tanzanian hospital
J Antimicrob Chemother, 65 (9), 1996-2000
DOI 10.1093/jac/dkq234, PubMed 20576637 -
Autophagic degradation of an oncoprotein
Autophagy, 6 (7), 964-5
DOI 10.4161/auto.6.7.13066, PubMed 20724820 -
Calprotectin (S100A8/S100A9) and myeloperoxidase: co-regulators of formation of reactive oxygen species
Toxins (Basel), 2 (1), 95-115
DOI 10.3390/toxins2010095, PubMed 22069549 -
Breast cancer, cytomegalovirus and Epstein-Barr virus: a nested case-control study
Br J Cancer, 102 (11), 1665-9
DOI 10.1038/sj.bjc.6605675, PubMed 20407437 -
Histone H3 lysine 27 methylation asymmetry on developmentally-regulated promoters distinguish the first two lineages in mouse preimplantation embryos
PLoS One, 5 (2), e9150
DOI 10.1371/journal.pone.0009150, PubMed 20161773 -
[Dramatic case report caused by a rare bacteria]
Tidsskr Nor Laegeforen, 130 (2), 149-51
DOI 10.4045/tidsskr.08.0715, PubMed 20125205 -
Reduced expression of DNA glycosylases in post-hypoxic newborn pigs undergoing therapeutic hypothermia
Brain Res, 1363, 198-205
DOI 10.1016/j.brainres.2010.09.080, PubMed 20883672 -
Molecular detection and identification of zygomycetes species from paraffin-embedded tissues in a murine model of disseminated zygomycosis: a collaborative European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Fungal Infection Study Group (EFISG) evaluation
J Clin Microbiol, 48 (6), 2043-6
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