Welcome to Stig Ove Bøe's research group: Cell and tissue dynamics
Our research group investigates how physical forces and properties integrate with molecular and biochemical mechanisms to regulate dynamic biological processes, such as cancer metastasis, wound healing, development and immune cell migration. We employ ex vivo and in vitro model systems in conjunction with advanced light microscopy and computational analysis to measure and map the physical and molecular features of dynamic cells and tissues. Additionally, we utilize mathematical modeling and numerical simulation to validate and elucidate our experimental findings. Our primary goal is to comprehend how cells utilize fundamental physical principles to execute complex dynamic behaviors under both normal and pathological conditions.