Virology Research Group

Mari KaarbøGroup leader
Mari Kaarbø
Group leader

The Virology Research Group at the Department of Microbiology (MIK), Oslo University Hospital/University of Oslo (UiO) is interested in the molecular and clinical aspects of human virus infections.  We use human immunodeficiency virus type 1 (HIV) and human cytomegalovirus (CMV) as model systems for chronic virus infections and our main focus is how these viruses affect their host cells with regard to latency, genome stability and their interaction with the immune system. In the light of the SARS-CoV-2 pandemic, we also have a number of projects involving this virus. We are in close collaboration with the Clinical Virology Research Group (https://www.ous-research.no/clinvir/)

Research projects

  • The role of dynamic methylome regulation during latent and active HIV infection
  • Molecular studies of immunological non responders during combined retroviral treatment
  • DNA repair and chromatin remodeling in CMV infection
  • Role of APOBEC deaminases during CMV infection
  • Dynamic methylome regulation during CMV latency and reactivation
  • Studies of HIV and CMV anti-retroviral resistance using next generation sequencing
  • Dynamic regulation of the transcriptome during SARS-CoV-2 infection
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