❭ Research by medical division ❭ Laboratory Medicine ❭ Dept. of Medical Genetics ❭ Cancer Genome Variation [Kristensen] ❭ Research projects ❭

Reseach project overview, Vessela N. Kristensen's group: Cancer Genome Variation

  • Genomic instability and treatment response
  • Integrated pathway analysis in breast cancer
  • The epigenetic landscape of cancer: application for prognostic and predictive biomarkers
  • Functional cellular, explant- and organoid systems
  • Integrated molecular analysis of miRNAs in breast cancer with clinical outcome
  • Genetic and epigenetic mechanisms underlying treatment response
  • Germline biomarkers for clinical management of sporadic and familiar tumors
  • The immune system in breast carcinogenesis and treatment response
  • NorMa: Normal mammary tissue and cancer development
  • Sequencing the non-canonical genomes
 
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Recent publications

Campos-Segura AV, Alvarez K, Murillo Carrasco AG, Rossi BM, Bohorquez M, Spirandelli F, Benavides C, Balto A, Della Valle A, Bruno LI, Lopez-Kostner F, Cruz-Correa M, Del Monte JS, Rugeles J, Ramirez JM, Nascimento I, Forones NM, Cock-Rada AM, Reyes-Silva C, Avila S, Apolinario L, Rossi NT, Martin C, Sulcahuaman Y, Vaccaro CA et al. (2025)
Characterization of Screening Strategies for Lynch Syndrome in Latin America
Clin Gastroenterol Hepatol (in press)
DOI 10.1016/j.cgh.2024.12.026, PubMed 40010418

Hoppe R, Winter S, Lo WY, Michailidou K, Bolla MK, Keeman R, Wang Q, Dennis J, Lush M, Kalari KR, Goetz MP, Wang L, Cairns J, Weinshilboum R, Shepherd L, Chen BE, Häberle L, Ruebner M, Beckmann MW, He W, Larson NL, Armasu SM, Schroth W, Chowbay B, Khor CC et al. (2025)
Lessons learned from a candidate gene study investigating aromatase inhibitor treatment outcome in breast cancer
NPJ Breast Cancer, 11 (1), 18
DOI 10.1038/s41523-025-00733-y, PubMed 39971965

Martiniussen MA, Larsen M, Hovda T, Kristiansen MU, Dahl FA, Eikvil L, Brautaset O, Bjørnerud A, Kristensen V, Bergan MB, Hofvind S (2025)
Performance of Two Deep Learning-based AI Models for Breast Cancer Detection and Localization on Screening Mammograms from BreastScreen Norway
Radiol Artif Intell, 7 (3), e240039
DOI 10.1148/ryai.240039, PubMed 39907587

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