Reseach project overview, Vessela N. Kristensen's group: Cancer Genome Variation

Ankill J, Zhao Z, Tekpli X, Kure EH, Kristensen VN, Mathelier A, Fleischer T (2024)
Integrative pan-cancer analysis reveals a common architecture of dysregulated transcriptional networks characterized by loss of enhancer methylation
PLoS Comput Biol, 20 (11), e1012565 (in press)
DOI 10.1371/journal.pcbi.1012565, PubMed 39556603

Zanti M, O'Mahony DG, Parsons MT, Dorling L, Dennis J, Boddicker NJ, Chen W, Hu C, Naven M, Yiangou K, Ahearn TU, Ambrosone CB, Andrulis IL, Antoniou AC, Auer PL, Baynes C, Bodelon C, Bogdanova NV, Bojesen SE, Bolla MK, Brantley KD, Camp NJ, Campbell A, Castelao JE, Cessna MH et al. (2024)
Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification
medRxiv
DOI 10.1101/2024.09.04.24313051, PubMed 39281752

Liu Y, Peng C, Brorson IS, O'Mahony DG, Kelly RL, Heng YJ, Baker GM, Grenaker Alnæs GI, Bodelon C, Stover DG, Van Allen EM, Eliassen AH, Kristensen VN, Tamimi RM, Kraft P (2024)
Germline polygenic risk scores are associated with immune gene expression signature and immune cell infiltration in breast cancer
Am J Hum Genet, 111 (10), 2150-2163
DOI 10.1016/j.ajhg.2024.08.009, PubMed 39270649