News

2022

Xavier Tekpli leads Strategic Research Area at OUS
https://oslo-universitetssykehus.no/om-oss/nyheter/tre-nye-strategiske-forskningsomrader-utpekt-ved-oslo-universitetssykehus

2021

To av våre beste går over til bioteknologiselskap
Multiomics-sekvensering av enkeltceller og spatial-karakterisering av kreftsvulster for å bekjempe resistens mot kreftbehandling - Oslo universitetssykehus HF (oslo-universitetssykehus.no)

" Jeg, robot," i klinisk praksis?
https://oslo-universitetssykehus.no/avdelinger/klinikk-for-laboratoriemedisin/avdeling-for-medisinsk-genetikk/seksjon-for-forskning-og-utvikling-medisinsk-genetikk/-jeg-robot-i-klinisk-praksis

Vessela Kristensen Blogs: The optimistic geneticist (8.7K views)
https://youtu.be/3AomYyD_eCU

Inside the head of a researcher: Cancer is a genetic disease
https://www.ous-research.no/home/ous/news/21550

2020

From cancer to other genetic diseases
https://oslo-universitetssykehus.no/avdelinger/klinikk-for-laboratoriemedisin/avdeling-for-medisinsk-genetikk/inni-forskerhodet-fra-kreftforskning-til-andre-genetiske-sykdommer

"Elsk dine gener" Popular talk for the Research Council of Norway
https://www.youtube.com/watch?v=TI0IT01I71A

Brystkreft for kvinner flest
https://1.6millionerklubben.no/oversikt-over-seminarer/vessela-kristensen/

Being a project coordinator means achieving recognition from your peers (RESCUER project)
https://www.med.uio.no/english/about/news-and-events/news/2020/being-a-project-coordinator-means-achieving-recogn.html

Computer modeling as a new way to improve breast cancer treatment (RESCUER project)
https://www.med.uio.no/english/about/news-and-events/news/2020/computer-modeling-as-a-new-way-to-improve-breast-c.html

Four Pink Ribbon research projects with our active participation
https://brystkreftforskning.no/1434-2/

https://www.med.uio.no/ncmm/english/news-and-events/profiles/translating-basic-research-into-clinical-practice-.html
In-depth profile: Translating basic research into clinical practice

2019

New immune-related breast cancer subtypes described in Nature Communications
https://www.ous-research.no/home/ous/news/20339

Vil behandle kreft før den oppstår
https://radiumlegat.no/Prosjekter/2019/Vessela-Kristensen

Vessela Kristensen appointed Head of Research at the Department of Medical Genetics
https://www.ous-research.no/home/ous/news/20157

Hvordan diagnostisere tidlig?
https://www.amta.no/i-dag-behandler-vi-kreft-forst-nar-den-har-brutt-ut-da-er-det-ofte-for-sent/s/5-3-500979

CNN coverage: - Major study of genetics of breast cancer provides clues to mechanisms behind the disease
https://www.ous-research.no/home/ous/Homepage%20news/17775

Presenting our collaboration with IARC
https://www.youtube.com/watch?v=jip1SsR0OTI

2018

Bruker datasimulering for å finne den beste kreftbehandlingen
https://titan.uio.no/naturvitenskap-livsvitenskap/2018/bruker-datasimulering-finne-den-beste-kreftbehandlingen

We welcome our new summer students from the Life Science initiative; Emilie Eliseussen Ødegaard (M.Sc. in mathematics) and Severin Langberg (computer scientist).

https://www.nature.com/collections/bhkhbxstgj

King Olav V's cancer research award for 2018 went to professor Vessela Kristensen, head of the Cancer Genome Variation Group at the Department of Cancer Genetics at the Institute for Cancer Research.

The prestigious prize was handed over by HM Kong Harald V on behalf of the Norwegian Cancer Society in Oslo on April 16th. 

New: The Norwegian Cancer Society has recently published a feature article about Vessela Kristensen and her research.

The authors demonstrate the power of meta-analysis to identify rare somatic variants in cancer, and they identify several copy number alterations of potential importance for tumor development in those affected. The paper contributes to the understanding of the diversity of evolutionary processes in cancer.
The study, published online in Nature Communications on 31 October, is collaboration between OUS, UiO and several international partners. First author Jiqiu Cheng from the Hege Russnes group at the Department of Cancer Genetics at the Institute for Cancer Research. The senior author of the paper is Peter Van Loo at the Francis Crick Institute in UK.

Thomas Fleischer and Xavier Tekpli from the Cancer Genome Variation group, led by Vessela Kristensen at the Department of Cancer Genetics, IKF, together with their collaborators from the NCMM, Toni Hurtado and Anthony Mathelier, and Professor Arnoldo Frigessi from UiO identified methylated regions (CpGs) that show remarkably and reproducibly conserved patterns of association to gene expression in the DNA from breast tumors in three independent breast cancer cohorts. 
The article - entitled “DNA methylation at enhancers identifies distinct breast cancer lineages” has been selected for the Editors’ Highlights webpage of recent research on Genomes and Epigenomes, put together by the editors at Nature Communications.

The article "Targeting of cancer neoantigens with donor-derived T cell receptor repertoires" by Erlend Strønen et al, published in Science in June 2016, is highlighted by an editorial in the "Clinical Implications of Basic Research" section in the Feb 2nd edition of New England Journal of Medicine.

The editorial is entitled "The Antigenicity of the Tumor Cell — Context Matters".

As part of the Oslo Breast Cancer Consortium (OSBREAC), surgeons, oncologist and Scientists from OUS have participated in the analysis of genetic data from 275,000 women, of whom 146,000 had been diagnosed with breast cancer.
Seventy-two new genetic variants that contribute to the risk of developing breast cancer have been identified by a major international collaboration involving hundreds of researchers worldwide.
Of these variants, reported October 23rd in the journals Nature and Nature Genetics, 65 are common variants that predispose to breast cancer and a further seven predispose specifically to oestrogen-receptor negative breast cancer – the subset of cases that do not respond to hormonal therapies.
The findings are the result of work by the OncoArray Consortium, a huge endeavour involving 550 researchers from around 300 different institutions in six continents of which OSBREAC is a part of.
The Principle Investigator of the Norwegian part of the study is professor Vessela N. Kristensen from the Department of Cancer Genetics at the Institute for Cancer Research.
The studies are covered by world-wide media channels, such as CNN.