The research group is dedicated to advancing the diagnosis and treatment of cancer by utilizing genome technologies. The research projects are primarily focused on prostate cancer, alongside ovarian, testicular, and colorectal cancers. Cancer genomes and transcriptomes are analysed by a combination of computational biology and wet-lab based approaches. Mutation analyses in cancer clearly benefit from information on which genes and variants that are actually expressed. In this line, the group has specialized particularly in RNA-level analyses. Meaningful translational and genome-scale cancer research demands interdisciplinary synergy, and the group members draw upon their diverse academic backgrounds in biology, informatics, and medicine.

The research group includes a project group in Cancer informatics, led by Dr. Bjarne Johannessen.

Diseases
Prostate cancer
Ovarian cancer
Testicular germ cell tumour
Colorectal cancer

Projects
Interfocal heterogeneity of prostate cancer, and implications for precision cancer management
Cancer genomics
Structural DNA and RNA variation, including fusion genes, as a source of cancer biomarkers

Information to patients
Prostate cancer research project (in Norwegian)

Contact information:

Department of molecular oncology, Institute for cancer research
Oslo university hospital-Radiumhospitalet
P.O.Box 4953 Nydalen, NO-0424 Oslo, Norway
Phone: +47 2278 1727 / +47 2293 4000
E mail: rolfis@uio.no