❭ Research by medical division ❭ Cancer Medicine ❭ Institute for Cancer Research ❭ Dept. of Cancer Genetics ❭ Translational studies on solid tumours [Helland] ❭ Clinical trials ❭ COM-IT-2 ❭

COM-IT-2 Immunotherapy combined with extensive radiotherapy for the treatment of stage IV non-small cell lung cancer

– a phase II randomised clinical and translational trial

  • EudraCT number: 2021-003266
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Home Dept. of Cancer Genetics Translational studies on solid tumours [Helland]

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Recent publications

Hektoen HH, Tsuruda KM, Brustugun OT, Neumann K, Andreassen BK (2025)
Real-world comparison of pembrolizumab alone and combined with chemotherapy in metastatic lung adenocarcinoma patients with PD-L1 expression ≥50
ESMO Open, 10 (5), 105073 (in press)
DOI 10.1016/j.esmoop.2025.105073, PubMed 40305908

Tsuruda KM, Hektoen HH, Aamelfot C, Andreassen BK (2025)
Let's talk about sex: Survival among females and males in a real-world cohort treated with pembrolizumab for non-small cell lung cancer
Int J Cancer (in press)
DOI 10.1002/ijc.35445, PubMed 40298324

Schytte T, Knap MM, Kristiansen C, Appelt AL, Khalil A, Peucelle C, Lutz CM, Møller DS, Sande EPS, Sundby F, Persson G, Schmidt H, Land LH, Rogg L, Pøhl M, Lund MD, Nielsen M, Levin N, Hansen O, Thing RS, Borissova S, Halvorsen T, Nielsen TB, Hansen TS, Haakensen VD et al. (2025)
Toxicity Within 6 Months of Heterogeneous Fluorodeoxyglucose-Guided Radiotherapy Dose Escalation for Locally Advanced Non-Small Cell Lung Cancer in the Scandinavian Randomized Phase III NARLAL2 Trial
J Clin Oncol, JCO2401386 (in press)
DOI 10.1200/JCO-24-01386, PubMed 40249893

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