Publications from OUS - Translational studies in solid tumors (Helland)

228 publications found

Publications 2025

  1. Alver TN, Bergholtz H, Holm MB, Dorg LT, Skrede ML, Kure EH, Verbeke CS (2025)
    Spatial Transcriptomics Reveals Cancer and Stromal Cell Heterogeneity Between Center and Invasive Front of Pancreatic Cancer
    Mod Pathol, 38 (6), 100726 (in press)
    DOI 10.1016/j.modpat.2025.100726, PubMed 39889965
  2. Bergholtz H, Norum JH, Lien TG, Skrede ML, Garred Ø, Sørlie T (2025)
    B cells and energy metabolism in HER2-positive DCIS: insights into breast cancer progression from spatial-omics analyses
    Breast Cancer Res, 27 (1), 44
    DOI 10.1186/s13058-025-01990-2, PubMed 40119362
  3. Nyen JE, Booth AØ, Husby Ø, Bugge C, Engebretsen I, Oteiza F, Helland Å, Fjellbirkeland L, Brustugun OT, Grønberg BH (2025)
    Targeted treatment and survival in advanced non-squamous non-small cell lung cancer patients - a nationwide and longitudinal study
    Front Oncol, 15, 1506041
    DOI 10.3389/fonc.2025.1506041, PubMed 40052133
  4. Nyen JE, Booth AØ, Husby Ø, Bugge C, Engebretsen I, Oteiza F, Helland Å, Fjellbirkeland L, Brustugun OT, Grønberg BH (2025)
    Corrigendum: Targeted treatment and survival in advanced non-squamous non-small cell lung cancer patients - a nationwide and longitudinal study
    Front Oncol, 15, 1595028
    DOI 10.3389/fonc.2025.1595028, PubMed 40206591
  5. Rakaee M, Tafavvoghi M, Ricciuti B, Alessi JV, Cortellini A, Citarella F, Nibid L, Perrone G, Adib E, Fulgenzi CAM, Hidalgo Filho CM, Di Federico A, Jabar F, Hashemi S, Houda I, Richardsen E, Rasmussen Busund LT, Donnem T, Bahce I, Pinato DJ, Helland Å, Sholl LM, Awad MM, Kwiatkowski DJ (2025)
    Deep Learning Model for Predicting Immunotherapy Response in Advanced Non-Small Cell Lung Cancer
    JAMA Oncol, 11 (2), 109-118
    DOI 10.1001/jamaoncol.2024.5356, PubMed 39724105
  6. Schytte T, Knap MM, Kristiansen C, Appelt AL, Khalil A, Peucelle C, Lutz CM, Møller DS, Sande EPS, Sundby F, Persson G, Schmidt H, Land LH, Rogg L, Pøhl M, Lund MD, Nielsen M, Levin N, Hansen O, Thing RS, Borissova S, Halvorsen T, Nielsen TB, Hansen TS, Haakensen VD et al. (2025)
    Toxicity Within 6 Months of Heterogeneous Fluorodeoxyglucose-Guided Radiotherapy Dose Escalation for Locally Advanced Non-Small Cell Lung Cancer in the Scandinavian Randomized Phase III NARLAL2 Trial
    J Clin Oncol, JCO2401386 (in press)
    DOI 10.1200/JCO-24-01386, PubMed 40249893
  7. Tsuruda KM, Hektoen HH, Reis Costa D, Andreassen BK (2025)
    Immortal time bias in survival outcomes when comparing treatment with chemotherapy versus immunochemotherapy for non-small cell lung cancer
    Transl Lung Cancer Res, 14 (1), 300-302
    DOI 10.21037/tlcr-24-1002, PubMed 39958223

Publications 2024

  1. Ankill J, Zhao Z, Tekpli X, Kure EH, Kristensen VN, Mathelier A, Fleischer T (2024)
    Integrative pan-cancer analysis reveals a common architecture of dysregulated transcriptional networks characterized by loss of enhancer methylation
    PLoS Comput Biol, 20 (11), e1012565
    DOI 10.1371/journal.pcbi.1012565, PubMed 39556603
  2. Bjørgo E, Fagereng GL, Russnes HG, Smeland S, Taskén K, Helland Å (2024)
    Acta Oncologica Nordic Precision Cancer Medicine Symposium 2023 - merging clinical research and standard healthcare
    Acta Oncol, 63, 487-490
    DOI 10.2340/1651-226X.2024.24954, PubMed 38910311
  3. Brativnyk A, Ankill J, Helland Å, Fleischer T (2024)
    Multi-omics analysis reveals epigenetically regulated processes and patient classification in lung adenocarcinoma
    Int J Cancer, 155 (2), 282-297
    DOI 10.1002/ijc.34915, PubMed 38489486
  4. Braadland PR, Farnes I, Kure EH, Yaqub S, McCann A, Ueland PM, Labori KJ, Hov JR (2024)
    Indole 3-acetate and response to therapy in borderline resectable or locally advanced pancreatic cancer
    Front Oncol, 14, 1488749
    DOI 10.3389/fonc.2024.1488749, PubMed 39759130
  5. Chen L, Wang X, Xie N, Zhang Z, Xu X, Xue M, Yang Y, Liu L, Su L, Bjaanæs M, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Christiani DC, Chen F, Zhang R (2024)
    A two-phase epigenome-wide four-way gene-smoking interaction study of overall survival for early-stage non-small cell lung cancer
    Mol Oncol, 19 (1), 173-187
    DOI 10.1002/1878-0261.13766, PubMed 39630602
  6. Demir MF, Lin YH, Costa Cruz PH, Tajima M, Honjo T, Müller E (2024)
    Blocking S100A9-signaling is detrimental to the initiation of anti-tumor immunity
    Front Immunol, 15, 1479502
    DOI 10.3389/fimmu.2024.1479502, PubMed 39497822
  7. Farooqi SJ, Zhao Z, Öjlert ÅK, Thunold S, Juul HV, Bjaanæs MM, Horndalsveen H, Nymoen HMG, Helland Å, Haakensen VD (2024)
    Serum cytokines as a biomarker for immune checkpoint inhibitor toxicity in patients with pleural mesothelioma
    Front Immunol, 15, 1480183
    DOI 10.3389/fimmu.2024.1480183, PubMed 39687621
  8. Filippi AR, Bar J, Chouaid C, Christoph DC, Field JK, Fietkau R, Garassino MC, Garrido P, Haakensen VD, Kao S, Markman B, McDonald F, Mornex F, Moskovitz M, Peters S, Sibille A, Siva S, van den Heuvel M, Vercauter P, Anand S, Chander P, Licour M, de Lima AR, Qiao Y, Girard N (2024)
    Real-world outcomes with durvalumab after chemoradiotherapy in patients with unresectable stage III NSCLC: interim analysis of overall survival from PACIFIC-R
    ESMO Open, 9 (6), 103464
    DOI 10.1016/j.esmoop.2024.103464, PubMed 38833971
  9. Førde D, Kilvær T, Pedersen MI, Blix ES, Urbarova I, Paulsen EE, Rakaee M, Busund LR, Donnem T, Andersen S (2024)
    High density of TCF1+ stem-like tumor-infiltrating lymphocytes is associated with favorable disease-specific survival in NSCLC
    Front Immunol, 15, 1504220
    DOI 10.3389/fimmu.2024.1504220, PubMed 39749327
  10. Gullhaug A, Haakensen VD, De Ruysscher D, Simone CB, Hotca-Cho AE, Chhabra AM, Hellebust TP, Paulsen EE, Dimopoulos MP, Johansen S (2024)
    Lung cancer reirradiation: Exploring modifications to utilization, treatment modalities and factors associated with outcomes
    J Med Imaging Radiat Sci, 55 (2), 221-231
    DOI 10.1016/j.jmir.2024.02.004, PubMed 38429174
  11. Hamfjord J, Guren TK, Glimelius B, Sorbye H, Pfeiffer P, Dajani O, Lingjærde OC, Tveit KM, Spindler KG, Pallisgaard N, Kure EH (2024)
    Exploring Early Kinetic Profiles of CEA, ctDNA and cfDNA in Patients With RAS-/BRAF-Mutated Metastatic Colorectal Cancer
    Clin Colorectal Cancer (in press)
    DOI 10.1016/j.clcc.2024.11.004, PubMed 39743478
  12. Hektoen HH, Tsuruda KM, Fjellbirkeland L, Nilssen Y, Brustugun OT, Andreassen BK (2024)
    Real-world evidence for pembrolizumab in non-small cell lung cancer: a nationwide cohort study
    Br J Cancer, 132 (1), 93-102
    DOI 10.1038/s41416-024-02895-1, PubMed 39489879
  13. Helland Å (2024)
    [Not Available]
    Tidsskr Nor Laegeforen, 144 (15)
    DOI 10.4045/tidsskr.24.0603, PubMed 39692664
  14. Helland Å, Steinskog ESS, Blix ES, Flobak Å, Brabrand S, Puco K, Niehusmann P, Meltzer S, Oppedal IA, Haug Å, Torkildsen CF, Randen U, Gilje B, Lønning PE, Gjertsen BT, Hovland R, Russnes HG, Fagereng GL, Smeland S, Tasken K (2024)
    [Raising the quality of cancer treatment]
    Tidsskr Nor Laegeforen, 144 (1)
    DOI 10.4045/tidsskr.23.0740, PubMed 38258713
  15. Haakensen VD, Öjlert ÅK, Thunold S, Farooqi S, Nowak AK, Chin WL, Grundberg O, Szejniuk WM, Cedres S, Sørensen JB, Dalen TS, Lund-Iversen M, Bjaanæs M, Helland Å (2024)
    UV1 telomerase vaccine with ipilimumab and nivolumab as second line treatment for pleural mesothelioma - A phase II randomised trial
    Eur J Cancer, 202, 113973
    DOI 10.1016/j.ejca.2024.113973, PubMed 38447379
  16. Mahon P, Chatzitheofilou I, Dekker A, Fernández X, Hall G, Helland A, Traverso A, Van Marcke C, Vehreschild J, Ciliberto G, Tonon G (2024)
    A federated learning system for precision oncology in Europe: DigiONE
    Nat Med, 30 (2), 334-337
    DOI 10.1038/s41591-023-02715-8, PubMed 38195748
  17. Miceli R, Eriksson H, Lo Russo G, Alfieri S, Moksnes Bjaanæs M, Pietrantonio F, De Cecco L, Prelaj A, Proto C, Franzén J, McDonnell D, Berenguer Pina JJ, Beninato T, Mazzeo L, Giannatempo P, Verzoni E, Crown J, Helland Å, Eustace A (2024)
    Gender Difference in sidE eFfects of ImmuNotherapy: a possible clue to optimize cancEr tReatment (G-DEFINER): study protocol of an observational prospective multicenter study
    Acta Oncol, 63, 213-219
    DOI 10.2340/1651-226X.2024.24179, PubMed 38647024
  18. Nymoen HM, Alver TN, Horndalsveen H, Eide HA, Bjaanæs MM, Brustugun OT, Grønberg BH, Haakensen VD, Helland Å (2024)
    Thoracic radiation in combination with erlotinib-results from a phase 2 randomized trial
    Front Oncol, 14, 1412716
    DOI 10.3389/fonc.2024.1412716, PubMed 39148905
  19. Puco K, Fagereng GL, Brabrand S, Niehusmann P, Støre Blix E, Samdal Steinskog ES, Haug Å, Fredvik Torkildsen C, Oppedal IA, Meltzer S, Flobak Å, Johansson KAM, Bjørge L, Hjortland GO, Dalhaug A, Lund JÅ, Gilje B, Grønlie Cameron M, Hovland R, Falk RS, Smeland S, Giercksky Russnes HE, Taskén K, Helland Å, InPreD Consortium et al. (2024)
    IMPRESS-Norway: improving public cancer care by implementing precision medicine in Norway; inclusion rates and preliminary results
    Acta Oncol, 63, 379-384
    DOI 10.2340/1651-226X.2024.28322, PubMed 38779911
  20. Ringborg U, von Braun J, Celis J, Baumann M, Berns A, Eggermont A, Heard E, Heitor M, Chandy M, Chen CJ, Costa A, De Lorenzo F, De Robertis EM, Dubee FC, Ernberg I, Gabriel M, Helland Å, Henrique R, Jönsson B, Kallioniemi O, Korbel J, Krause M, Lowy DR, Michielin O, Nagy P et al. (2024)
    Strategies to decrease inequalities in cancer therapeutics, care and prevention: Proceedings on a conference organized by the Pontifical Academy of Sciences and the European Academy of Cancer Sciences, Vatican City, February 23-24, 2023
    Mol Oncol, 18 (2), 245-279
    DOI 10.1002/1878-0261.13575, PubMed 38135904
  21. Stålberg SM, Silwal-Pandit L, Bastani NE, Nebdal DJH, Lingjærde OC, Skålhegg BS, Kure EH (2024)
    Preoperative profiles of plasma amino acids and derivatives distinguish periampullary cancer and benign disease
    BMC Cancer, 24 (1), 555
    DOI 10.1186/s12885-024-12320-8, PubMed 38702616
  22. Tafavvoghi M, Sildnes A, Rakaee M, Shvetsov N, Bongo LA, Busund LR, Møllersen K (2024)
    Deep learning-based classification of breast cancer molecular subtypes from H&E whole-slide images
    J Pathol Inform, 16, 100410
    DOI 10.1016/j.jpi.2024.100410, PubMed 39720418
  23. Taskén K, F Haj Mohammad S, Fagereng GL, Sørum Falk R, Helland Å, Barjesteh van Waalwijk van Doorn-Khosrovani S, Steen Carlsson K, Ryll B, Jalkanen K, Edsjö A, Russnes HG, Lassen U, Hallersjö Hult E, Lugowska I, Blay JY, Verlingue L, Abel E, Lowery MA, Krebs MG, Staal Rohrberg K, Ojamaa K, Oliveira J, Verheul HMW, Voest EE, Gelderblom H et al. (2024)
    PCM4EU and PRIME-ROSE: Collaboration for implementation of precision cancer medicine in Europe
    Acta Oncol, 63, 385-391
    DOI 10.2340/1651-226X.2024.34791, PubMed 38779910
  24. Thunold S, Hernes E, Farooqi S, Öjlert ÅK, Francis RJ, Nowak AK, Szejniuk WM, Nielsen SS, Cedres S, Perdigo MS, Sørensen JB, Meltzer C, Mikalsen LTG, Helland Å, Malinen E, Haakensen VD (2024)
    Outcome prediction based on [18F]FDG PET/CT in patients with pleural mesothelioma treated with ipilimumab and nivolumab +/- UV1 telomerase vaccine
    Eur J Nucl Med Mol Imaging, 52 (2), 693-707
    DOI 10.1007/s00259-024-06853-0, PubMed 39133306

Publications 2023

  1. Børø S, Thoresen S, Boge Brant S, Helland Å (2023)
    Initial investigation of using Norwegian health data for the purpose of external comparator arms - an example for non-small cell lung cancer
    Acta Oncol, 62 (12), 1642-1648
    DOI 10.1080/0284186X.2023.2264484, PubMed 37801361
  2. Langberg CW, Horndalsveen H, Helland Å, Haakensen VD (2023)
    Factors associated with failure to start consolidation durvalumab after definitive chemoradiation for locally advanced NSCLC
    Front Oncol, 13, 1217424
    DOI 10.3389/fonc.2023.1217424, PubMed 37476372
  3. Le Tourneau C, André F, Helland Å, Mileshkin L, Minnaard W, Schiel A, Taskén K, Thomas DM, Veronese ML, Durán-Pacheco G, Leyens L, Rufibach K, Thomas M, Krämer A (2023)
    Modified study designs to expand treatment options in personalised oncology: a multistakeholder view
    Eur J Cancer, 194, 113278
    DOI 10.1016/j.ejca.2023.113278, PubMed 37820553
  4. Skoie IM, Skogås JG, Langø T, Myhr KM, Myhre PL, Goll R, Fretland SØ, Helland Å (2023)
    New centres to carry out more clinical trials in Norway
    Tidsskr Nor Laegeforen, 143 (2)
    DOI 10.4045/tidsskr.22.0722, PubMed 36718905

Publications 2022

  1. Alver TN, Heintz KM, Hovig E, Bøe SL (2022)
    Cooperative induction of receptor tyrosine kinases contributes to adaptive MAPK drug resistance in melanoma through the PI3K pathway
    Cancer Rep (Hoboken), 6 (2), e1736
    DOI 10.1002/cnr2.1736, PubMed 36251678
  2. Berg J, Halvorsen AR, Bengtson MB, Lindberg M, Halvorsen B, Aukrust P, Helland Å, Ueland T (2022)
    Circulating T Cell Activation and Exhaustion Markers Are Associated With Radiation Pneumonitis and Poor Survival in Non-Small-Cell Lung Cancer
    Front Immunol, 13, 875152
    DOI 10.3389/fimmu.2022.875152, PubMed 35911763
  3. Berg J, Halvorsen AR, Bengtson MB, Lindberg M, Halvorsen B, Aukrust P, Helland Å, Ueland T (2022)
    Corrigendum: Circulating T cell activation and exhaustion markers are associated with radiation pneumonitis and poor survival in non-small-cell lung cancer
    Front Immunol, 13, 1051156
    DOI 10.3389/fimmu.2022.1051156, PubMed 36263024
  4. Børø S, Thoresen S, Helland Å (2022)
    Improvements in survival for patients with stage IV adenocarcinoma in the lung, diagnosed between 2010 - 2020 - A population-based registry study from Norway
    Front Oncol, 12, 1017902
    DOI 10.3389/fonc.2022.1017902, PubMed 36523970
  5. Callesen LB, Hamfjord J, Boysen AK, Pallisgaard N, Guren TK, Kure EH, Spindler KG (2022)
    Circulating tumour DNA and its clinical utility in predicting treatment response or survival in patients with metastatic colorectal cancer: a systematic review and meta-analysis
    Br J Cancer, 127 (3), 500-513
    DOI 10.1038/s41416-022-01816-4, PubMed 35440666
  6. Chen J, Song Y, Li Y, Wei Y, Shen S, Zhao Y, You D, Su L, Bjaanaes MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Shen H, Christiani DC, Zhang R, Chen F (2022)
    A trans-omics assessment of gene-gene interaction in early-stage NSCLC
    Mol Oncol, 17 (1), 173-187
    DOI 10.1002/1878-0261.13345, PubMed 36408734
  7. Eide IJZ, Stensgaard S, Helland Å, Ekman S, Mellemgaard A, Hansen KH, Cicenas S, Koivunen J, Grønberg BH, Sørensen BS, Brustugun OT (2022)
    Osimertinib in non-small cell lung cancer with uncommon EGFR-mutations: a post-hoc subgroup analysis with pooled data from two phase II clinical trials
    Transl Lung Cancer Res, 11 (6), 953-963
    DOI 10.21037/tlcr-21-995, PubMed 35832438
  8. Girard N, Bar J, Garrido P, Garassino MC, McDonald F, Mornex F, Filippi AR, Smit HJM, Peters S, Field JK, Christoph DC, Sibille A, Fietkau R, Haakensen VD, Chouaid C, Markman B, Hiltermann TJN, Taus A, Sawyer W, Allen A, Chander P, Licour M, Solomon B (2022)
    Treatment Characteristics and Real-World Progression-Free Survival in Patients With Unresectable Stage III NSCLC Who Received Durvalumab After Chemoradiotherapy: Findings From the PACIFIC-R Study
    J Thorac Oncol, 18 (2), 181-193
    DOI 10.1016/j.jtho.2022.10.003, PubMed 36307040
  9. Gulati G, Tjessem KH, Horndalsveen H, Halvorsen S, Haakensen VD (2022)
    [Checkpoint inhibitor-induced myocarditis]
    Tidsskr Nor Laegeforen, 142 (18)
    DOI 10.4045/tidsskr.21.0817, PubMed 36511752
  10. Helland Å, Andersen KK, Myklebust TÅ, Johannesen TB, Aarøe J, Enerly E (2022)
    EGFR-mutation testing and TKI treatment patterns in locally advanced and metastatic NSCLC in Norway - A nationwide retrospective cohort study
    Cancer Treat Res Commun, 33, 100636
    DOI 10.1016/j.ctarc.2022.100636, PubMed 36155129
  11. Helland Å, Russnes HG, Fagereng GL, Al-Shibli K, Andersson Y, Berg T, Bjørge L, Blix E, Bjerkehagen B, Brabrand S, Cameron MG, Dalhaug A, Dietzel D, Dønnem T, Enerly E, Flobak Å, Fluge S, Gilje B, Gjertsen BT, Grønberg BH, Grønås K, Guren T, Hamre H, Haug Å, Heinrich D et al. (2022)
    Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
    J Transl Med, 20 (1), 225
    DOI 10.1186/s12967-022-03432-5, PubMed 35568909
  12. Helland Å, Russnes HG, Fagereng GL, Al-Shibli K, Andersson Y, Berg T, Bjørge L, Blix E, Bjerkehagen B, Brabrand S, Cameron MG, Dalhaug A, Dietzel D, Dønnem T, Enerly E, Flobak Å, Fluge S, Gilje B, Gjertsen BT, Grønberg BH, Grønås K, Guren T, Hamre H, Haug Å, Heinrich D et al. (2022)
    Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
    J Transl Med, 20 (1), 317
    DOI 10.1186/s12967-022-03518-0, PubMed 35841045
  13. Horndalsveen H, Alver TN, Dalsgaard AM, Rogg LV, Helbekkmo N, Grønberg BH, Halvorsen TO, Ramberg C, Haakensen VD, Öjlert ÅK, Bjaanaes MM, Helland Å (2022)
    Atezolizumab and stereotactic body radiotherapy in patients with advanced non-small cell lung cancer: safety, clinical activity and ctDNA responses-the ComIT-1 trial
    Mol Oncol, 17 (3), 487-498
    DOI 10.1002/1878-0261.13330, PubMed 36330681
  14. Ji X, Lin L, Fan J, Li Y, Wei Y, Shen S, Su L, Shafer A, Bjaanaes MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Zhang R, Chen F, Christiani DC (2022)
    Epigenome-wide three-way interaction study identifies a complex pattern between TRIM27, KIAA0226, and smoking associated with overall survival of early-stage NSCLC
    Mol Oncol, 16 (3), 717-731
    DOI 10.1002/1878-0261.13167, PubMed 34932879
  15. Khadse A, Haakensen VD, Silwal-Pandit L, Hamfjord J, Micke P, Botling J, Brustugun OT, Lingjærde OC, Helland Å, Kure EH (2022)
    Prognostic Significance of the Loss of Heterozygosity of KRAS in Early-Stage Lung Adenocarcinoma
    Front Oncol, 12, 873532
    DOI 10.3389/fonc.2022.873532, PubMed 35574381
  16. Maggadóttir SM, Kvalheim G, Wernhoff P, Sæbøe-Larssen S, Revheim ME, Josefsen D, Wälchli S, Helland Å, Inderberg EM (2022)
    A phase I/II escalation trial design T-RAD: Treatment of metastatic lung cancer with mRNA-engineered T cells expressing a T cell receptor targeting human telomerase reverse transcriptase (hTERT)
    Front Oncol, 12, 1031232
    DOI 10.3389/fonc.2022.1031232, PubMed 36439452
  17. Silwal-Pandit L, Stålberg SM, Johansson HJ, Mermelekas G, Lothe IMB, Skrede ML, Dalsgaard AM, Nebdal DJH, Helland Å, Lingjærde OC, Labori KJ, Skålhegg BS, Lehtiö J, Kure EH (2022)
    Proteome Analysis of Pancreatic Tumors Implicates Extracellular Matrix in Patient Outcome
    Cancer Res Commun, 2 (6), 434-446
    DOI 10.1158/2767-9764.CRC-21-0100, PubMed 36923555
  18. Taskén K, Russnes HEG, Aas E, Bjørge L, Blix ES, CONNECT Public–Private Partnership Consortium, Enerly E, Fagereng GL, Flobak Å, Gilje B, Gjertsen BT, Guren TK, Heix J, Hovig E, Hovland R, InPreD-Norway and National Molecular Tumor Board Consortium, IMPRESS-Norway Consortium, Lønning PE, Meza-Zepeda LA, Mæhle PM, Nilsen HL, Thoresen SØ, Widerberg K, Smeland S, Helland Å (2022)
    A national precision cancer medicine implementation initiative for Norway
    Nat Med, 28 (5), 885-887
    DOI 10.1038/s41591-022-01777-4, PubMed 35513529
  19. Umu SU, Langseth H, Zuber V, Helland Å, Lyle R, Rounge TB (2022)
    Serum RNAs can predict lung cancer up to 10 years prior to diagnosis
    Elife, 11
    DOI 10.7554/eLife.71035, PubMed 35147498

Publications 2021

  1. Berg J, Ramberg C, Haugstvedt JOS, Bengtson MB, Gabrielsen AM, Brustugun OT, Halvorsen AR, Helland Å (2021)
    Lung Function After Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer, Changes and Predictive Markers
    Front Oncol, 11, 674731
    DOI 10.3389/fonc.2021.674731, PubMed 34109123
  2. Bjaanæs MM, Nilsen G, Halvorsen AR, Russnes HG, Solberg S, Jørgensen L, Brustugun OT, Lingjærde OC, Helland Å (2021)
    Whole genome copy number analyses reveal a highly aberrant genome in TP53 mutant lung adenocarcinoma tumors
    BMC Cancer, 21 (1), 1089
    DOI 10.1186/s12885-021-08811-7, PubMed 34625038
  3. Bjaanæs MM, Sande EPS, Loe Ø, Ramberg C, Næss TM, Ottestad A, Rogg LV, Svestad JG, Haakensen VD (2021)
    Improved adaptive radiotherapy to adjust for anatomical alterations during curative treatment for locally advanced lung cancer
    Phys Imaging Radiat Oncol, 18, 51-54
    DOI 10.1016/j.phro.2021.04.003, PubMed 34258408
  4. Eide IJZ, Grut H, Helland Å, Ekman S, Sørensen JB, Hansen KH, Grønberg BH, Cicenas S, Koivunen JP, Mellemgaard A, Brustugun OT (2021)
    Intracranial effect of osimertinib in relapsed EGFR-mutated T790M-positive and -negative non-small cell lung cancer patients: results from a phase II study
    Acta Oncol, 60 (12), 1565-1571
    DOI 10.1080/0284186X.2021.1973092, PubMed 34486915
  5. Farooqi SJ, Bjaanæs MM, Helland Å, Haakensen VD (2021)
    [Immunotherapy for malignant pleural mesothelioma]
    Tidsskr Nor Laegeforen, 141
    DOI 10.4045/tidsskr.21.0503, PubMed 34505475
  6. Farooqi SJ, Helland A, Haakensen VD, Bjaanaes MM (2021)
    Immunotherapy in malignant pleural mesothelioma
    Tidsskr. Nor. Laegeforen., 141 (12), 1167-1169
  7. Frafjord A, Buer L, Hammarström C, Aamodt H, Woldbæk PR, Brustugun OT, Helland Å, Øynebråten I, Corthay A (2021)
    The Immune Landscape of Human Primary Lung Tumors Is Th2 Skewed
    Front Immunol, 12, 764596
    DOI 10.3389/fimmu.2021.764596, PubMed 34868011
  8. Hamfjord J, Guren TK, Glimelius B, Sorbye H, Pfeiffer P, Dajani O, Lingjaerde OC, Tveit KM, Pallisgaard N, Spindler KG, Kure EH (2021)
    Clinicopathological factors associated with tumour-specific mutation detection in plasma of patients with RAS-mutated or BRAF-mutated metastatic colorectal cancer
    Int J Cancer, 149 (6), 1385-1397
    DOI 10.1002/ijc.33672, PubMed 33961700
  9. Hamfjord J, Myklebust TÅ, Larsen IK, Kure EH, Glimelius B, Guren TK, Tveit KM, Guren MG (2021)
    Survival Trends of Right- and Left-Sided Colon Cancer across Four Decades: A Norwegian Population-Based Study
    Cancer Epidemiol Biomarkers Prev, 31 (2), 342-351
    DOI 10.1158/1055-9965.EPI-21-0555, PubMed 34853022
  10. Haakensen VD, Nowak AK, Ellingsen EB, Farooqi SJ, Bjaanæs MM, Horndalsveen H, Mcculloch T, Grundberg O, Cedres SM, Helland Å (2021)
    NIPU: a randomised, open-label, phase II study evaluating nivolumab and ipilimumab combined with UV1 vaccination as second line treatment in patients with malignant mesothelioma
    J Transl Med, 19 (1), 232
    DOI 10.1186/s12967-021-02905-3, PubMed 34059094
  11. Johannesen TB, Smeland S, Aaserud S, Buanes EA, Skog A, Ursin G, Helland Å (2021)
    COVID-19 in Cancer Patients, Risk Factors for Disease and Adverse Outcome, a Population-Based Study From Norway
    Front Oncol, 11, 652535
    DOI 10.3389/fonc.2021.652535, PubMed 33842366
  12. Lehtiö J, Arslan T, Siavelis I, Pan Y, Socciarelli F, Berkovska O, Umer HM, Mermelekas G, Pirmoradian M, Jönsson M, Brunnström H, Brustugun OT, Purohit KP, Cunningham R, Foroughi Asl H, Isaksson S, Arbajian E, Aine M, Karlsson A, Kotevska M, Gram Hansen C, Drageset Haakensen V, Helland Å, Tamborero D, Johansson HJ et al. (2021)
    Proteogenomics of non-small cell lung cancer reveals molecular subtypes associated with specific therapeutic targets and immune evasion mechanisms
    Nat Cancer, 2 (11), 1224-1242
    DOI 10.1038/s43018-021-00259-9, PubMed 34870237
  13. Terkelsen T, Pernemalm M, Gromov P, Børresen-Dale AL, Krogh A, Haakensen VD, Lethiö J, Papaleo E, Gromova I (2021)
    High-throughput proteomics of breast cancer interstitial fluid: identification of tumor subtype-specific serologically relevant biomarkers
    Mol Oncol, 15 (2), 429-461
    DOI 10.1002/1878-0261.12850, PubMed 33176066
  14. Öjlert ÅK, Nebdal D, Snapkov I, Olsen V, Kidman J, Greiff V, Chee J, Helland Å (2021)
    Dynamic changes in the T cell receptor repertoire during treatment with radiotherapy combined with an immune checkpoint inhibitor
    Mol Oncol, 15 (11), 2958-2968
    DOI 10.1002/1878-0261.13082, PubMed 34402187

Publications 2020

  1. Abravan A, Eide HA, Helland Å, Malinen E (2020)
    Radiotherapy-related lymphopenia in patients with advanced non-small cell lung cancer receiving palliative radiotherapy
    Clin Transl Radiat Oncol, 22, 15-21
    DOI 10.1016/j.ctro.2020.02.005, PubMed 32181373
  2. Brustugun OT, Sorhaug S, Gronberg BH, Aanerud M, Al-Zubayidy MMZ, Fjellbirkeland L, Helland A, Berg J, Andreassen B, Paulsen EE, Haram PM, Ashraf H, Wahl SGF (2020)
    Lung cancer: Improved prognosis presents capacity challenges
    Tidsskr. Nor. Laegeforen., 140 (5), 432-434
  3. Eide IJZ, Helland Å, Ekman S, Mellemgaard A, Hansen KH, Cicenas S, Koivunen J, Grønberg BH, Brustugun OT (2020)
    Osimertinib in T790M-positive and -negative patients with EGFR-mutated advanced non-small cell lung cancer (the TREM-study)
    Lung Cancer, 143, 27-35
    DOI 10.1016/j.lungcan.2020.03.009, PubMed 32200138
  4. Frafjord A, Skarshaug R, Hammarström C, Stankovic B, Dorg LT, Aamodt H, Woldbaek PR, Helland Å, Brustugun OT, Øynebråten I, Corthay A (2020)
    Antibody combinations for optimized staining of macrophages in human lung tumours
    Scand J Immunol, 92 (1), e12889
    DOI 10.1111/sji.12889, PubMed 32299134
  5. Goleva-Fjellet S, Bjurholt AM, Kure EH, Larsen IK, Støren Ø, Sæbø M (2020)
    Distribution of allele frequencies for genes associated with physical activity and/or physical capacity in a homogenous Norwegian cohort- a cross-sectional study
    BMC Genet, 21 (1), 8
    DOI 10.1186/s12863-020-0813-1, PubMed 31973699
  6. Halvorsen AR, Haugen MH, Öjlert ÅK, Lund-Iversen M, Jørgensen L, Solberg S, Mælandsmo GM, Brustugun OT, Helland Å (2020)
    Protein Kinase C Isozymes Associated With Relapse Free Survival in Non-Small Cell Lung Cancer Patients
    Front Oncol, 10, 590755
    DOI 10.3389/fonc.2020.590755, PubMed 33324562
  7. Haakensen VD, Khadse A, Sandhu V, Halvorsen AR, Solberg SK, Jørgensen LH, Brustugun OT, Kure EH, Helland Å (2020)
    Molecular characterisation of TP53 mutated squamous cell carcinomas of the lung to identify putative targets for therapy
    Int J Cancer, 147 (10), 2957-2966
    DOI 10.1002/ijc.33121, PubMed 32468587
  8. Ji X, Lin L, Shen S, Dong X, Chen C, Li Y, Zhu Y, Huang H, Chen J, Chen X, Wei L, He J, Duan W, Su L, Jiang Y, Fan J, Guan J, You D, Shafer A, Bjaanaes MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M et al. (2020)
    Epigenetic-smoking interaction reveals histologically heterogeneous effects of TRIM27 DNA methylation on overall survival among early-stage NSCLC patients
    Mol Oncol, 14 (11), 2759-2774
    DOI 10.1002/1878-0261.12785, PubMed 33448640
  9. Stankovic B, Aamodt H, Bjørhovde HAK, Müller E, Hammarström C, Brustugun OT, Helland Å, Øynebråten I, Corthay A (2020)
    The immune microenvironment in typical carcinoid lung tumour, a brief report of four cases
    Scand J Immunol, 92 (2), e12893
    DOI 10.1111/sji.12893, PubMed 32433774
  10. Terkelsen T, Russo F, Gromov P, Haakensen VD, Brunak S, Gromova I, Krogh A, Papaleo E (2020)
    Secreted breast tumor interstitial fluid microRNAs and their target genes are associated with triple-negative breast cancer, tumor grade, and immune infiltration
    Breast Cancer Res, 22 (1), 73
    DOI 10.1186/s13058-020-01295-6, PubMed 32605588
  11. Umu SU, Langseth H, Keller A, Meese E, Helland Å, Lyle R, Rounge TB (2020)
    A 10-year prediagnostic follow-up study shows that serum RNA signals are highly dynamic in lung carcinogenesis
    Mol Oncol, 14 (2), 235-247
    DOI 10.1002/1878-0261.12620, PubMed 31851411
  12. Zhang R, Chen C, Dong X, Shen S, Lai L, He J, You D, Lin L, Zhu Y, Huang H, Chen J, Wei L, Chen X, Li Y, Guo Y, Duan W, Liu L, Su L, Shafer A, Fleischer T, Moksnes Bjaanæs M, Karlsson A, Planck M, Wang R, Staaf J et al. (2020)
    Independent Validation of Early-Stage Non-Small Cell Lung Cancer Prognostic Scores Incorporating Epigenetic and Transcriptional Biomarkers With Gene-Gene Interactions and Main Effects
    Chest, 158 (2), 808-819
    DOI 10.1016/j.chest.2020.01.048, PubMed 32113923
  13. Öjlert ÅK, Nebdal D, Lund-Iversen M, Åstrøm Ellefsen R, Brustugun OT, Gran JM, Halvorsen AR, Helland Å (2020)
    Immune checkpoint blockade in the treatment of advanced non-small cell lung cancer - predictors of response and impact of previous radiotherapy
    Acta Oncol, 60 (2), 149-156
    DOI 10.1080/0284186X.2020.1854851, PubMed 33356733

Publications 2019

  1. Abravan A, Eide HA, Løndalen AM, Helland Å, Malinen E (2019)
    Mapping Bone Marrow Response in the Vertebral Column by Positron Emission Tomography Following Radiotherapy and Erlotinib Therapy of Lung Cancer
    Mol Imaging Biol, 21 (2), 391-398
    DOI 10.1007/s11307-018-1226-7, PubMed 29916117
  2. Bergholtz H, Lien TG, Ursin G, Holmen MM, Helland Å, Sørlie T, Haakensen VD (2019)
    A Longitudinal Study of the Association between Mammographic Density and Gene Expression in Normal Breast Tissue
    J Mammary Gland Biol Neoplasia, 24 (2), 163-175
    DOI 10.1007/s10911-018-09423-x, PubMed 30613869
  3. Bowitz Lothe IM, Kleive D, Pomianowska E, Cvancarova M, Kure E, Dueland S, Gladhaug IP, Labori KJ (2019)
    Clinical relevance of pancreatobiliary and intestinal subtypes of ampullary and duodenal adenocarcinoma: Pattern of recurrence, chemotherapy, and survival after pancreatoduodenectomy
    Pancreatology, 19 (2), 316-324
    DOI 10.1016/j.pan.2019.01.019, PubMed 30713128
  4. Dong X, Zhang R, He J, Lai L, Alolga RN, Shen S, Zhu Y, You D, Lin L, Chen C, Zhao Y, Duan W, Su L, Shafer A, Salama M, Fleischer T, Bjaanæs MM, Karlsson A, Planck M, Wang R, Staaf J, Helland Å, Esteller M, Wei Y, Chen F et al. (2019)
    Trans-omics biomarker model improves prognostic prediction accuracy for early-stage lung adenocarcinoma
    Aging (Albany NY), 11 (16), 6312-6335
    DOI 10.18632/aging.102189, PubMed 31434796
  5. Halvorsen AR, Ragle Aure M, Õjlert ÅK, Brustugun OT, Solberg S, Nebdal D, Helland Å (2019)
    Identification of microRNAs involved in pathways which characterize the expression subtypes of NSCLC
    Mol Oncol, 13 (12), 2604-2615
    DOI 10.1002/1878-0261.12571, PubMed 31505091
  6. Hamfjord J, Guren TK, Dajani O, Johansen JS, Glimelius B, Sorbye H, Pfeiffer P, Lingjærde OC, Tveit KM, Kure EH, Pallisgaard N, Spindler KG (2019)
    Total circulating cell-free DNA as a prognostic biomarker in metastatic colorectal cancer before first-line oxaliplatin-based chemotherapy
    Ann Oncol, 30 (7), 1088-1095
    DOI 10.1093/annonc/mdz139, PubMed 31046124
  7. Nygård S, Lingjærde OC, Caldas C, Hovig E, Børresen-Dale AL, Helland Å, Haakensen VD (2019)
    PathTracer: High-sensitivity detection of differential pathway activity in tumours
    Sci Rep, 9 (1), 16332
    DOI 10.1038/s41598-019-52529-3, PubMed 31704995
  8. Sandhu V, Labori KJ, Borgida A, Lungu I, Bartlett J, Hafezi-Bakhtiari S, Denroche RE, Jang GH, Pasternack D, Mbaabali F, Watson M, Wilson J, Kure EH, Gallinger S, Haibe-Kains B (2019)
    Meta-Analysis of 1,200 Transcriptomic Profiles Identifies a Prognostic Model for Pancreatic Ductal Adenocarcinoma
    JCO Clin Cancer Inform, 3, 1-16
    DOI 10.1200/CCI.18.00102, PubMed 31070984
  9. Shao B, Bjaanæs MM, Helland Å, Schütte C, Conrad T (2019)
    EMT network-based feature selection improves prognosis prediction in lung adenocarcinoma
    PLoS One, 14 (1), e0204186
    DOI 10.1371/journal.pone.0204186, PubMed 30703089
  10. Stankovic B, Bjørhovde HAK, Skarshaug R, Aamodt H, Frafjord A, Müller E, Hammarström C, Beraki K, Bækkevold ES, Woldbæk PR, Helland Å, Brustugun OT, Øynebråten I, Corthay A (2019)
    Immune Cell Composition in Human Non-small Cell Lung Cancer
    Front Immunol, 9, 3101
    DOI 10.3389/fimmu.2018.03101, PubMed 30774636
  11. Zhang R, Lai L, Dong X, He J, You D, Chen C, Lin L, Zhu Y, Huang H, Shen S, Wei L, Chen X, Guo Y, Liu L, Su L, Shafer A, Moran S, Fleischer T, Bjaanaes MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Wei Y et al. (2019)
    SIPA1L3 methylation modifies the benefit of smoking cessation on lung adenocarcinoma survival: an epigenomic-smoking interaction analysis
    Mol Oncol, 13 (5), 1235-1248
    DOI 10.1002/1878-0261.12482, PubMed 30924596
  12. Zhang R, Lai L, He J, Chen C, You D, Duan W, Dong X, Zhu Y, Lin L, Shen S, Guo Y, Su L, Shafer A, Moran S, Fleischer T, Bjaanæs MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Wei Y, Chen F, Christiani DC (2019)
    EGLN2 DNA methylation and expression interact with HIF1A to affect survival of early-stage NSCLC
    Epigenetics, 14 (2), 118-129
    DOI 10.1080/15592294.2019.1573066, PubMed 30665327
  13. Öjlert ÅK, Halvorsen AR, Nebdal D, Lund-Iversen M, Solberg S, Brustugun OT, Lingjaerde OC, Helland Å (2019)
    The immune microenvironment in non-small cell lung cancer is predictive of prognosis after surgery
    Mol Oncol, 13 (5), 1166-1179
    DOI 10.1002/1878-0261.12475, PubMed 30854794

Publications 2018

  1. Berg J, Halvorsen AR, Bengtson MB, Taskén KA, Mælandsmo GM, Yndestad A, Halvorsen B, Brustugun OT, Aukrust P, Ueland T, Helland Å (2018)
    Levels and prognostic impact of circulating markers of inflammation, endothelial activation and extracellular matrix remodelling in patients with lung cancer and chronic obstructive pulmonary disease
    BMC Cancer, 18 (1), 739
    DOI 10.1186/s12885-018-4659-0, PubMed 30005623
  2. Eide HA, Knudtsen IS, Sandhu V, Løndalen AM, Halvorsen AR, Abravan A, Kure EH, Bogsrud TV, Brustugun OT, Kyte JA, Malinen E, Helland Å (2018)
    Serum cytokine profiles and metabolic tumor burden in patients with non-small cell lung cancer undergoing palliative thoracic radiation therapy
    Adv Radiat Oncol, 3 (2), 130-138
    DOI 10.1016/j.adro.2017.12.007, PubMed 29904737
  3. Gandara DR, von Pawel J, Mazieres J, Sullivan R, Helland Å, Han JY, Ponce Aix S, Rittmeyer A, Barlesi F, Kubo T, Park K, Goldschmidt J, Gandhi M, Yun C, Yu W, Matheny C, He P, Sandler A, Ballinger M, Fehrenbacher L (2018)
    Atezolizumab Treatment Beyond Progression in Advanced NSCLC: Results From the Randomized, Phase III OAK Study
    J Thorac Oncol, 13 (12), 1906-1918
    DOI 10.1016/j.jtho.2018.08.2027, PubMed 30217492
  4. Guo Y, Zhang R, Shen S, Wei Y, Salama SM, Fleischer T, Bjaanæs MM, Karlsson A, Planck M, Su L, Zhu Z, Staaf J, Helland Å, Esteller M, Christiani DC (2018)
    DNA Methylation of LRRC3B: A Biomarker for Survival of Early-Stage Non-Small Cell Lung Cancer Patients
    Cancer Epidemiol Biomarkers Prev, 27 (12), 1527-1535
    DOI 10.1158/1055-9965.EPI-18-0454, PubMed 30185536
  5. Halvorsen AR, Sandhu V, Sprauten M, Flote VG, Kure EH, Brustugun OT, Helland Å (2018)
    Circulating microRNAs associated with prolonged overall survival in lung cancer patients treated with nivolumab
    Acta Oncol, 57 (9), 1225-1231
    DOI 10.1080/0284186X.2018.1465585, PubMed 29683761
  6. Helland A (2018)
    Groundbreaking basic research
    Tidsskr. Nor. Laegeforen., 138 (20), 1905
  7. Jabeen S, Espinoza JA, Torland LA, Zucknick M, Kumar S, Haakensen VD, Lüders T, Engebraaten O, Børresen-Dale AL, Kyte JA, Gromov P, Naume B, Kristensen V, Gromova I, Tekpli X (2018)
    Noninvasive profiling of serum cytokines in breast cancer patients and clinicopathological characteristics
    Oncoimmunology, 8 (2), e1537691
    DOI 10.1080/2162402X.2018.1537691, PubMed 30713794
  8. Rye IH, Trinh A, Saetersdal AB, Nebdal D, Lingjaerde OC, Almendro V, Polyak K, Børresen-Dale AL, Helland Å, Markowetz F, Russnes HG (2018)
    Intratumor heterogeneity defines treatment-resistant HER2+ breast tumors
    Mol Oncol, 12 (11), 1838-1855
    DOI 10.1002/1878-0261.12375, PubMed 30133130
  9. Shen S, Zhang R, Guo Y, Loehrer E, Wei Y, Zhu Y, Yuan Q, Moran S, Fleischer T, Bjaanaes MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Su L, Chen F, Christiani DC (2018)
    A multi-omic study reveals BTG2 as a reliable prognostic marker for early-stage non-small cell lung cancer
    Mol Oncol, 12 (6), 913-924
    DOI 10.1002/1878-0261.12204, PubMed 29656435
  10. Terkelsen T, Haakensen VD, Saldova R, Gromov P, Hansen MK, Stöckmann H, Lingjaerde OC, Børresen-Dale AL, Papaleo E, Helland Å, Rudd PM, Gromova I (2018)
    N-glycan signatures identified in tumor interstitial fluid and serum of breast cancer patients: association with tumor biology and clinical outcome
    Mol Oncol, 12 (6), 972-990
    DOI 10.1002/1878-0261.12312, PubMed 29698574
  11. Thomsen M, Skovlund E, Sorbye H, Bolstad N, Nustad KJ, Glimelius B, Pfeiffer P, Kure EH, Johansen JS, Tveit KM, Christoffersen T, Guren TK (2018)
    Prognostic role of carcinoembryonic antigen and carbohydrate antigen 19-9 in metastatic colorectal cancer: a BRAF-mutant subset with high CA 19-9 level and poor outcome
    Br J Cancer, 118 (12), 1609-1616
    DOI 10.1038/s41416-018-0115-9, PubMed 29872151
  12. Wei Y, Liang J, Zhang R, Guo Y, Shen S, Su L, Lin X, Moran S, Helland Å, Bjaanæs MM, Karlsson A, Planck M, Esteller M, Fleischer T, Staaf J, Zhao Y, Chen F, Christiani DC (2018)
    Epigenetic modifications in KDM lysine demethylases associate with survival of early-stage NSCLC
    Clin Epigenetics, 10, 41
    DOI 10.1186/s13148-018-0474-3, PubMed 29619118

Publications 2017

  1. Abravan A, Eide HA, Knudtsen IS, Løndalen AM, Helland Å, Malinen E (2017)
    Assessment of pulmonary 18F-FDG-PET uptake and cytokine profiles in non-small cell lung cancer patients treated with radiotherapy and erlotinib
    Clin Transl Radiat Oncol, 4, 57-63
    DOI 10.1016/j.ctro.2017.04.002, PubMed 29594209
  2. Abravan A, Knudtsen IS, Eide HA, Løndalen AM, Helland Å, van Luijk P, Malinen E (2017)
    A new method to assess pulmonary changes using 18F-fluoro-2-deoxyglucose positron emission tomography for lung cancer patients following radiotherapy
    Acta Oncol, 56 (11), 1597-1603
    DOI 10.1080/0284186X.2017.1349336, PubMed 28849707
  3. Dannenfelser R, Nome M, Tahiri A, Ursini-Siegel J, Vollan HKM, Haakensen VD, Helland Å, Naume B, Caldas C, Børresen-Dale AL, Kristensen VN, Troyanskaya OG (2017)
    Data-driven analysis of immune infiltrate in a large cohort of breast cancer and its association with disease progression, ER activity, and genomic complexity
    Oncotarget, 8 (34), 57121-57133
    DOI 10.18632/oncotarget.19078, PubMed 28915659
  4. Fleischer T, Klajic J, Aure MR, Louhimo R, Pladsen AV, Ottestad L, Touleimat N, Laakso M, Halvorsen AR, Grenaker Alnæs GI, Riis ML, Helland Å, Hautaniemi S, Lønning PE, Naume B, Børresen-Dale AL, Tost J, Kristensen VN (2017)
    DNA methylation signature (SAM40) identifies subgroups of the Luminal A breast cancer samples with distinct survival
    Oncotarget, 8 (1), 1074-1082
    DOI 10.18632/oncotarget.13718, PubMed 27911866
  5. Guren TK, Thomsen M, Kure EH, Sorbye H, Glimelius B, Pfeiffer P, Österlund P, Sigurdsson F, Lothe IMB, Dalsgaard AM, Skovlund E, Christoffersen T, Tveit KM (2017)
    Cetuximab in treatment of metastatic colorectal cancer: final survival analyses and extended RAS data from the NORDIC-VII study
    Br J Cancer, 116 (10), 1271-1278
    DOI 10.1038/bjc.2017.93, PubMed 28399112
  6. Halvorsen AR, Kristensen G, Embleton A, Adusei C, Barretina-Ginesta MP, Beale P, Helland Å (2017)
    Evaluation of Prognostic and Predictive Significance of Circulating MicroRNAs in Ovarian Cancer Patients
    Dis Markers, 2017, 3098542
    DOI 10.1155/2017/3098542, PubMed 28293063
  7. McGowan M, Kleinberg L, Halvorsen AR, Helland Å, Brustugun OT (2017)
    NSCLC depend upon YAP expression and nuclear localization after acquiring resistance to EGFR inhibitors
    Genes Cancer, 8 (3-4), 497-504
    DOI 10.18632/genesandcancer.136, PubMed 28680534
  8. Mezheyeuski A, Strell C, Hrynchyk I, Guren TK, Dragomir A, Doroshenko T, Pashkova O, Gorgun J, Ruksha K, Pfeiffer P, Kure EH, Sorbye H, Edler D, Martling A, Glimelius B, Östman A, Portyanko A (2017)
    Treatment-related survival associations of claudin-2 expression in fibroblasts of colorectal cancer
    Virchows Arch, 472 (3), 395-405
    DOI 10.1007/s00428-017-2263-3, PubMed 29134439
  9. Saldova R, Haakensen VD, Rødland E, Walsh I, Stöckmann H, Engebraaten O, Børresen-Dale AL, Rudd PM (2017)
    Serum N-glycome alterations in breast cancer during multimodal treatment and follow-up
    Mol Oncol, 11 (10), 1361-1379
    DOI 10.1002/1878-0261.12105, PubMed 28657165
  10. Thomsen M, Guren MG, Skovlund E, Glimelius B, Hjermstad MJ, Johansen JS, Kure E, Sorbye H, Pfeiffer P, Christoffersen T, Guren TK, Tveit KM (2017)
    Health-related quality of life in patients with metastatic colorectal cancer, association with systemic inflammatory response and RAS and BRAF mutation status
    Eur J Cancer, 81, 26-35
    DOI 10.1016/j.ejca.2017.04.026, PubMed 28595137

Publications 2016

  1. Dunning AM, Michailidou K, Kuchenbaecker KB, Thompson D, French JD, Beesley J, Healey CS, Kar S, Pooley KA, Lopez-Knowles E, Dicks E, Barrowdale D, Sinnott-Armstrong NA, Sallari RC, Hillman KM, Kaufmann S, Sivakumaran H, Moradi Marjaneh M, Lee JS, Hills M, Jarosz M, Drury S, Canisius S, Bolla MK, Dennis J et al. (2016)
    Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170
    Nat Genet, 48 (4), 374-86
    DOI 10.1038/ng.3521, PubMed 26928228
  2. Eide HA, Halvorsen AR, Bjaanæs MM, Piri H, Holm R, Solberg S, Jørgensen L, Brustugun OT, Kiserud CE, Helland Å (2016)
    The MYCN-HMGA2-CDKN2A pathway in non-small cell lung carcinoma--differences in histological subtypes
    BMC Cancer, 16, 71
    DOI 10.1186/s12885-016-2104-9, PubMed 26858029
  3. Eide HA, Halvorsen AR, Sandhu V, Fåne A, Berg J, Haakensen VD, Kure EH, Brustugun OT, Kiserud CE, Kyte JA, Helland Å (2016)
    Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease
    Clin Transl Immunology, 5 (11), e109
    DOI 10.1038/cti.2016.65, PubMed 27990285
  4. Espinoza JA, Jabeen S, Batra R, Papaleo E, Haakensen V, Timmermans Wielenga V, Møller Talman ML, Brunner N, Børresen-Dale AL, Gromov P, Helland Å, Kristensen VN, Gromova I (2016)
    Cytokine profiling of tumor interstitial fluid of the breast and its relationship with lymphocyte infiltration and clinicopathological characteristics
    Oncoimmunology, 5 (12), e1248015
    DOI 10.1080/2162402X.2016.1248015, PubMed 28123884
  5. Halvorsen AR, Bjaanæs M, LeBlanc M, Holm AM, Bolstad N, Rubio L, Peñalver JC, Cervera J, Mojarrieta JC, López-Guerrero JA, Brustugun OT, Helland Å (2016)
    A unique set of 6 circulating microRNAs for early detection of non-small cell lung cancer
    Oncotarget, 7 (24), 37250-37259
    DOI 10.18632/oncotarget.9363, PubMed 27191990
  6. Halvorsen AR, Helland Å, Gromov P, Wielenga VT, Talman MM, Brunner N, Sandhu V, Børresen-Dale AL, Gromova I, Haakensen VD (2016)
    Profiling of microRNAs in tumor interstitial fluid of breast tumors - a novel resource to identify biomarkers for prognostic classification and detection of cancer
    Mol Oncol, 11 (2), 220-234
    DOI 10.1002/1878-0261.12025, PubMed 28145100
  7. Halvorsen AR, Silwal-Pandit L, Meza-Zepeda LA, Vodak D, Vu P, Sagerup C, Hovig E, Myklebost O, Børresen-Dale AL, Brustugun OT, Helland Å (2016)
    TP53 Mutation Spectrum in Smokers and Never Smoking Lung Cancer Patients
    Front Genet, 7, 85
    DOI 10.3389/fgene.2016.00085, PubMed 27242894
  8. Helland A (2016)
    MicroRNA-profiles in lung adenocarcinomas
    Expert Rev. Precis. Med. Drug Dev., 1 (5), 469-474
    DOI 10.1080/23808993.2016.1240011
  9. Haakensen VD, Nygaard V, Greger L, Aure MR, Fromm B, Bukholm IR, Lüders T, Chin SF, Git A, Caldas C, Kristensen VN, Brazma A, Børresen-Dale AL, Hovig E, Helland Å (2016)
    Subtype-specific micro-RNA expression signatures in breast cancer progression
    Int J Cancer, 139 (5), 1117-28
    DOI 10.1002/ijc.30142, PubMed 27082076
  10. Joly-Battaglini A, Hammarström C, Stankovic B, Aamodt H, Stjärne J, Brustugun OT, Helland Å, Øynebråten I, Corthay A (2016)
    Rituximab efficiently depletes B cells in lung tumors and normal lung tissue
    F1000Res, 5, 38
    DOI 10.12688/f1000research.7599.1, PubMed 27081474
  11. Kongsgaard A, Boye K, Fodstad Ø, Juell S, Jørgensen LH, Solberg S, Helland Å, Brustugun OT, Mælandsmo GM (2016)
    Detection of disseminated tumor cells in lymph nodes from patients with early stage non-small cell lung cancer
    Diagn Pathol, 11 (1), 50
    DOI 10.1186/s13000-016-0504-4, PubMed 27316334
  12. McGowan M, Hoven AS, Lund-Iversen M, Solberg S, Helland Å, Hirsch FR, Brustugun OT (2016)
    PIK3CA mutations as prognostic factor in squamous cell lung carcinoma
    Lung Cancer, 103, 52-57
    DOI 10.1016/j.lungcan.2016.11.018, PubMed 28024696
  13. Mezheyeuski A, Bradic Lindh M, Guren TK, Dragomir A, Pfeiffer P, Kure EH, Ikdahl T, Skovlund E, Corvigno S, Strell C, Pietras K, Ponten F, Mulder J, Qvortrup C, Portyanko A, Tveit KM, Glimelius B, Sorbye H, Östman A (2016)
    Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer
    Oncotarget, 7 (27), 41948-41958
    DOI 10.18632/oncotarget.9632, PubMed 27248825
  14. Sandhu V, Wedge DC, Bowitz Lothe IM, Labori KJ, Dentro SC, Buanes T, Skrede ML, Dalsgaard AM, Munthe E, Myklebost O, Lingjærde OC, Børresen-Dale AL, Ikdahl T, Van Loo P, Nord S, Kure EH (2016)
    The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma
    Cancer Res, 76 (17), 5092-102
    DOI 10.1158/0008-5472.CAN-16-0658, PubMed 27488532
  15. Tarpgaard LS, Ørum-Madsen MS, Christensen IJ, Nordgaard C, Noer J, Guren TK, Glimelius B, Sorbye H, Ikdahl T, Kure EH, Tveit KM, Nielsen HJ, Pfeiffer P, Brünner N, Moreira JM (2016)
    TIMP-1 is under regulation of the EGF signaling axis and promotes an aggressive phenotype in KRAS-mutated colorectal cancer cells: a potential novel approach to the treatment of metastatic colorectal cancer
    Oncotarget, 7 (37), 59441-59457
    DOI 10.18632/oncotarget.11118, PubMed 27509063
  16. Thomsen M, Kersten C, Sorbye H, Skovlund E, Glimelius B, Pfeiffer P, Johansen JS, Kure EH, Ikdahl T, Tveit KM, Christoffersen T, Guren TK (2016)
    Interleukin-6 and C-reactive protein as prognostic biomarkers in metastatic colorectal cancer
    Oncotarget, 7 (46), 75013-75022
    DOI 10.18632/oncotarget.12601, PubMed 27738330
  17. Weischenfeldt J, Dubash T, Drainas AP, Mardin BR, Chen Y, Stütz AM, Waszak SM, Bosco G, Halvorsen AR, Raeder B, Efthymiopoulos T, Erkek S, Siegl C, Brenner H, Brustugun OT, Dieter SM, Northcott PA, Petersen I, Pfister SM, Schneider M, Solberg SK, Thunissen E, Weichert W, Zichner T, Thomas R et al. (2016)
    Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking
    Nat Genet, 49 (1), 65-74
    DOI 10.1038/ng.3722, PubMed 27869826

Publications 2015

  1. Andersen V, Vogel LK, Kopp TI, Sæbø M, Nonboe AW, Hamfjord J, Kure EH, Vogel U (2015)
    High ABCC2 and low ABCG2 gene expression are early events in the colorectal adenoma-carcinoma sequence
    PLoS One, 10 (3), e0119255
    DOI 10.1371/journal.pone.0119255, PubMed 25793771
  2. Baekelandt BM, Hjermstad MJ, Nordby T, Fagerland MW, Kure EH, Heiberg T, Buanes T, Labori KJ (2015)
    Preoperative cognitive function predicts survival in patients with resectable pancreatic ductal adenocarcinoma
    HPB (Oxford), 18 (3), 247-54
    DOI 10.1016/j.hpb.2015.09.004, PubMed 27017164
  3. Berg J, Fjellbirkeland L, Suhrke P, Jebsen P, Lund-Iversen M, Kleinberg L, Helgeland L, Brustugun OT, Helland Å (2015)
    EGFR mutation testing of lung cancer patients - Experiences from Vestfold Hospital Trust
    Acta Oncol, 55 (2), 149-55
    DOI 10.3109/0284186X.2015.1062537, PubMed 26313507
  4. Bjaanæs MM, Fleischer T, Halvorsen AR, Daunay A, Busato F, Solberg S, Jørgensen L, Kure E, Edvardsen H, Børresen-Dale AL, Brustugun OT, Tost J, Kristensen V, Helland Å (2015)
    Genome-wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis
    Mol Oncol, 10 (2), 330-43
    DOI 10.1016/j.molonc.2015.10.021, PubMed 26601720
  5. Costa-Silva B, Aiello NM, Ocean AJ, Singh S, Zhang H, Thakur BK, Becker A, Hoshino A, Mark MT, Molina H, Xiang J, Zhang T, Theilen TM, García-Santos G, Williams C, Ararso Y, Huang Y, Rodrigues G, Shen TL, Labori KJ, Lothe IM, Kure EH, Hernandez J, Doussot A, Ebbesen SH et al. (2015)
    Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
    Nat Cell Biol, 17 (6), 816-26
    DOI 10.1038/ncb3169, PubMed 25985394
  6. Darabi H, McCue K, Beesley J, Michailidou K, Nord S, Kar S, Humphreys K, Thompson D, Ghoussaini M, Bolla MK, Dennis J, Wang Q, Canisius S, Scott CG, Apicella C, Hopper JL, Southey MC, Stone J, Broeks A, Schmidt MK, Scott RJ, Lophatananon A, Muir K, Beckmann MW, Ekici AB et al. (2015)
    Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression
    Am J Hum Genet, 97 (1), 22-34
    DOI 10.1016/j.ajhg.2015.05.002, PubMed 26073781
  7. Hamfjord J, Saldova R, Stöckmann H, Sandhu V, Bowitz Lothe IM, Buanes T, Lingjærde OC, Labori KJ, Rudd PM, Kure EH (2015)
    Serum N-Glycome Characterization in Patients with Resectable Periampullary Adenocarcinoma
    J Proteome Res, 14 (12), 5144-56
    DOI 10.1021/acs.jproteome.5b00395, PubMed 26515733
  8. Helland A (2015)
    Gene jockeys Life science and the rise of biotech enterprise.
    Tidsskr. Nor. Laegeforen., 135 (4), 356
    DOI 10.4045/tidsskr.14.1367
  9. Helland A (2015)
    Cancer stem cells
    Tidsskr. Nor. Laegeforen., 135 (8), 783
    DOI 10.4045/tidsskr.15.0031
  10. Helland A (2015)
    Viruses and human cancer
    Tidsskr. Nor. Laegeforen., 135 (9), 874
    DOI 10.4045/tidsskr.15.0167
  11. Hoshino A, Costa-Silva B, Shen TL, Rodrigues G, Hashimoto A, Tesic Mark M, Molina H, Kohsaka S, Di Giannatale A, Ceder S, Singh S, Williams C, Soplop N, Uryu K, Pharmer L, King T, Bojmar L, Davies AE, Ararso Y, Zhang T, Zhang H, Hernandez J, Weiss JM, Dumont-Cole VD, Kramer K et al. (2015)
    Tumour exosome integrins determine organotropic metastasis
    Nature, 527 (7578), 329-35
    DOI 10.1038/nature15756, PubMed 26524530
  12. Haakensen VD, Steinfeld I, Saldova R, Shehni AA, Kifer I, Naume B, Rudd PM, Børresen-Dale AL, Yakhini Z (2015)
    Serum N-glycan analysis in breast cancer patients--Relation to tumour biology and clinical outcome
    Mol Oncol, 10 (1), 59-72
    DOI 10.1016/j.molonc.2015.08.002, PubMed 26321095
  13. Kjersem JB, Thomsen M, Guren T, Hamfjord J, Carlsson G, Gustavsson B, Ikdahl T, Indrebø G, Pfeiffer P, Lingjærde O, Tveit KM, Wettergren Y, Kure EH (2015)
    AGXT and ERCC2 polymorphisms are associated with clinical outcome in metastatic colorectal cancer patients treated with 5-FU/oxaliplatin
    Pharmacogenomics J, 16 (3), 272-9
    DOI 10.1038/tpj.2015.54, PubMed 26261061
  14. Labori KJ, Katz MH, Tzeng CW, Bjørnbeth BA, Cvancarova M, Edwin B, Kure EH, Eide TJ, Dueland S, Buanes T, Gladhaug IP (2015)
    Impact of early disease progression and surgical complications on adjuvant chemotherapy completion rates and survival in patients undergoing the surgery first approach for resectable pancreatic ductal adenocarcinoma - A population-based cohort study
    Acta Oncol, 55 (3), 265-77
    DOI 10.3109/0284186X.2015.1068445, PubMed 26213211
  15. Potapenko IO, Lüders T, Russnes HG, Helland Å, Sørlie T, Kristensen VN, Nord S, Lingjærde OC, Børresen-Dale AL, Haakensen VD (2015)
    Glycan-related gene expression signatures in breast cancer subtypes; relation to survival
    Mol Oncol, 9 (4), 861-76
    DOI 10.1016/j.molonc.2014.12.013, PubMed 25655580
  16. Sandhu V, Bowitz Lothe IM, Labori KJ, Skrede ML, Hamfjord J, Dalsgaard AM, Buanes T, Dube G, Kale MM, Sawant S, Kulkarni-Kale U, Børresen-Dale AL, Lingjærde OC, Kure EH (2015)
    Differential expression of miRNAs in pancreatobiliary type of periampullary adenocarcinoma and its associated stroma
    Mol Oncol, 10 (2), 303-16
    DOI 10.1016/j.molonc.2015.10.011, PubMed 26590090
  17. Syljuåsen RG, Hasvold G, Hauge S, Helland Å (2015)
    Targeting lung cancer through inhibition of checkpoint kinases
    Front Genet, 6, 70
    DOI 10.3389/fgene.2015.00070, PubMed 25774168

Publications 2014

  1. Almendro V, Cheng YK, Randles A, Itzkovitz S, Marusyk A, Ametller E, Gonzalez-Farre X, Muñoz M, Russnes HG, Helland A, Rye IH, Borresen-Dale AL, Maruyama R, van Oudenaarden A, Dowsett M, Jones RL, Reis-Filho J, Gascon P, Gönen M, Michor F, Polyak K (2014)
    Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity
    Cell Rep, 6 (3), 514-27
    DOI 10.1016/j.celrep.2013.12.041, PubMed 24462293
  2. Bjaanaes MM, Halvorsen AR, Solberg S, Jørgensen L, Dragani TA, Galvan A, Colombo F, Anderlini M, Pastorino U, Kure E, Børresen-Dale AL, Brustugun OT, Helland A (2014)
    Unique microRNA-profiles in EGFR-mutated lung adenocarcinomas
    Int J Cancer, 135 (8), 1812-21
    DOI 10.1002/ijc.28828, PubMed 24599520
  3. Fleischer T, Frigessi A, Johnson KC, Edvardsen H, Touleimat N, Klajic J, Riis ML, Haakensen VD, Wärnberg F, Naume B, Helland A, Børresen-Dale AL, Tost J, Christensen BC, Kristensen VN (2014)
    Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis
    Genome Biol, 15 (8), 435
    DOI 10.1186/PREACCEPT-2333349012841587, PubMed 25146004
  4. Halvorsen AR, Helland A, Fleischer T, Haug KM, Grenaker Alnaes GI, Nebdal D, Syljuåsen RG, Touleimat N, Busato F, Tost J, Saetersdal AB, Børresen-Dale AL, Kristensen V, Edvardsen H (2014)
    Differential DNA methylation analysis of breast cancer reveals the impact of immune signaling in radiation therapy
    Int J Cancer, 135 (9), 2085-95
    DOI 10.1002/ijc.28862, PubMed 24658971
  5. Kjersem JB, Skovlund E, Ikdahl T, Guren T, Kersten C, Dalsgaard AM, Yilmaz MK, Fokstuen T, Tveit KM, Kure EH (2014)
    FCGR2A and FCGR3A polymorphisms and clinical outcome in metastatic colorectal cancer patients treated with first-line 5-fluorouracil/folinic acid and oxaliplatin +/- cetuximab
    BMC Cancer, 14, 340
    DOI 10.1186/1471-2407-14-340, PubMed 24884501
  6. Saldova R, Asadi Shehni A, Haakensen VD, Steinfeld I, Hilliard M, Kifer I, Helland A, Yakhini Z, Børresen-Dale AL, Rudd PM (2014)
    Association of N-glycosylation with breast carcinoma and systemic features using high-resolution quantitative UPLC
    J Proteome Res, 13 (5), 2314-27
    DOI 10.1021/pr401092y, PubMed 24669823
  7. Sandhu V, Bowitz Lothe IM, Labori KJ, Lingjærde OC, Buanes T, Dalsgaard AM, Skrede ML, Hamfjord J, Haaland T, Eide TJ, Børresen-Dale AL, Ikdahl T, Kure EH (2014)
    Molecular signatures of mRNAs and miRNAs as prognostic biomarkers in pancreatobiliary and intestinal types of periampullary adenocarcinomas
    Mol Oncol, 9 (4), 758-71
    DOI 10.1016/j.molonc.2014.12.002, PubMed 25579086
  8. Tarpgaard LS, Guren TK, Glimelius B, Christensen IJ, Pfeiffer P, Kure EH, Sorbye H, Ikdahl T, Yilmaz M, Johansen JS, Tveit KM (2014)
    Plasma YKL-40 in patients with metastatic colorectal cancer treated with first line oxaliplatin-based regimen with or without cetuximab: RESULTS from the NORDIC VII Study
    PLoS One, 9 (2), e87746
    DOI 10.1371/journal.pone.0087746, PubMed 24498368
  9. Trinh A, Rye IH, Almendro V, Helland A, Russnes HG, Markowetz F (2014)
    GoIFISH: a system for the quantification of single cell heterogeneity from IFISH images
    Genome Biol, 15 (8), 442
    DOI 10.1186/s13059-014-0442-y, PubMed 25168174
  10. Vogel LK, Sæbø M, Høyer H, Kopp TI, Vogel U, Godiksen S, Frenzel FB, Hamfjord J, Bowitz-Lothe IM, Johnson E, Kure EH, Andersen V (2014)
    Intestinal PTGS2 mRNA levels, PTGS2 gene polymorphisms, and colorectal carcinogenesis
    PLoS One, 9 (8), e105254
    DOI 10.1371/journal.pone.0105254, PubMed 25166592
  11. Wennerström AB, Lothe IM, Sandhu V, Kure EH, Myklebost O, Munthe E (2014)
    Generation and characterisation of novel pancreatic adenocarcinoma xenograft models and corresponding primary cell lines
    PLoS One, 9 (8), e103873
    DOI 10.1371/journal.pone.0103873, PubMed 25148029

Publications 2013

  1. Andersen V, Vogel U, Godiksen S, Frenzel FB, Sæbø M, Hamfjord J, Kure E, Vogel LK (2013)
    Low ABCB1 gene expression is an early event in colorectal carcinogenesis
    PLoS One, 8 (8), e72119
    DOI 10.1371/journal.pone.0072119, PubMed 23977225
  2. Baumbusch LO, Helland Å, Wang Y, Liestøl K, Schaner ME, Holm R, Etemadmoghadam D, Alsop K, Brown P, Australian Ovarian Cancer Study Group, Mitchell G, Fereday S, DeFazio A, Bowtell DD, Kristensen GB, Lingjærde OC, Børresen-Dale AL (2013)
    High levels of genomic aberrations in serous ovarian cancers are associated with better survival
    PLoS One, 8 (1), e54356
    DOI 10.1371/journal.pone.0054356, PubMed 23372714
  3. Choudhury S, Almendro V, Merino VF, Wu Z, Maruyama R, Su Y, Martins FC, Fackler MJ, Bessarabova M, Kowalczyk A, Conway T, Beresford-Smith B, Macintyre G, Cheng YK, Lopez-Bujanda Z, Kaspi A, Hu R, Robens J, Nikolskaya T, Haakensen VD, Schnitt SJ, Argani P, Ethington G, Panos L, Grant M et al. (2013)
    Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics
    Cell Stem Cell, 13 (1), 117-30
    DOI 10.1016/j.stem.2013.05.004, PubMed 23770079
  4. Kjersem JB, Ikdahl T, Lingjaerde OC, Guren T, Tveit KM, Kure EH (2013)
    Plasma microRNAs predicting clinical outcome in metastatic colorectal cancer patients receiving first-line oxaliplatin-based treatment
    Mol Oncol, 8 (1), 59-67
    DOI 10.1016/j.molonc.2013.09.001, PubMed 24119443
  5. Kongsgaard A, Boye K, Oijordsbakken M, Lund-Iversen M, Halvorsen AR, Solberg SK, Berge G, Helland A, Brustugun OT, Mælandsmo GM (2013)
    Osteopontin is a prognostic biomarker in non-small cell lung cancer
    BMC Cancer, 13, 540
    DOI 10.1186/1471-2407-13-540, PubMed 24215488
  6. Nordby T, Ikdahl T, Bowitz Lothe IM, Fagerland MW, Heiberg T, Hauge T, Labori KJ, Buanes T (2013)
    Improved survival and quality of life in patients undergoing R1 pancreatic resection compared to patients with locally advanced unresectable pancreatic adenocarcinoma
    Pancreatology, 13 (2), 180-5
    DOI 10.1016/j.pan.2013.01.003, PubMed 23561977
  7. Nordgård O, Singh G, Solberg S, Jørgensen L, Halvorsen AR, Smaaland R, Brustugun OT, Helland Å (2013)
    Novel molecular tumor cell markers in regional lymph nodes and blood samples from patients undergoing surgery for non-small cell lung cancer
    PLoS One, 8 (5), e62153
    DOI 10.1371/journal.pone.0062153, PubMed 23671585
  8. Rajaram M, Zhang J, Wang T, Li J, Kuscu C, Qi H, Kato M, Grubor V, Weil RJ, Helland A, Borrenson-Dale AL, Cho KR, Levine DA, Houghton AN, Wolchok JD, Myeroff L, Markowitz SD, Lowe SW, Zhang M, Krasnitz A, Lucito R, Mu D, Powers RS (2013)
    Two Distinct Categories of Focal Deletions in Cancer Genomes
    PLoS One, 8 (6), e66264
    DOI 10.1371/journal.pone.0066264, PubMed 23805207

Publications 2012

  1. Brustugun OT, Helland Å, Fjellbirkeland L, Kleinberg L, Ariansen S, Jebsen P, Scott H, Dønnem T, Bremnes R, Berg T, Grønberg BH, Dai HY, Wahl SG, Mangseth K, Helgeland L (2012)
    [Mutation testing for non-small-cell lung cancer]
    Tidsskr Nor Laegeforen, 132 (8), 952-5
    DOI 10.4045/tidsskr.11.1017, PubMed 22562326
  2. Hamfjord J, Stangeland AM, Hughes T, Skrede ML, Tveit KM, Ikdahl T, Kure EH (2012)
    Differential expression of miRNAs in colorectal cancer: comparison of paired tumor tissue and adjacent normal mucosa using high-throughput sequencing
    PLoS One, 7 (4), e34150
    DOI 10.1371/journal.pone.0034150, PubMed 22529906
  3. Kjersem JB, Ikdahl T, Guren T, Skovlund E, Sorbye H, Hamfjord J, Pfeiffer P, Glimelius B, Kersten C, Solvang H, Tveit KM, Kure EH (2012)
    Let-7 miRNA-binding site polymorphism in the KRAS 3'UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin +/- cetuximab
    BMC Cancer, 12, 534
    DOI 10.1186/1471-2407-12-534, PubMed 23167843
  4. Kure EH, Hamfjord J, Stangeland AM, Tveit KM, Ikdahl T (2012)
    KRAS mutational test for metastatic colorectal cancer patients: not just a technical problem
    Expert Rev Mol Diagn, 12 (4), 327-8
    DOI 10.1586/erm.12.29, PubMed 22616697
  5. Riis ML, Lüders T, Markert EK, Haakensen VD, Nesbakken AJ, Kristensen VN, Bukholm IR (2012)
    Molecular profiles of pre- and postoperative breast cancer tumours reveal differentially expressed genes
    ISRN Oncol, 2012, 450267
    DOI 10.5402/2012/450267, PubMed 23227362
  6. Tveit KM, Guren T, Glimelius B, Pfeiffer P, Sorbye H, Pyrhonen S, Sigurdsson F, Kure E, Ikdahl T, Skovlund E, Fokstuen T, Hansen F, Hofsli E, Birkemeyer E, Johnsson A, Starkhammar H, Yilmaz MK, Keldsen N, Erdal AB, Dajani O, Dahl O, Christoffersen T (2012)
    Phase III trial of cetuximab with continuous or intermittent fluorouracil, leucovorin, and oxaliplatin (Nordic FLOX) versus FLOX alone in first-line treatment of metastatic colorectal cancer: the NORDIC-VII study
    J Clin Oncol, 30 (15), 1755-62
    DOI 10.1200/JCO.2011.38.0915, PubMed 22473155

Publications 2011

  1. Bornholdt J, Friis S, Godiksen S, Poulsen SS, Santoni-Rugiu E, Bisgaard HC, Lothe IM, Ikdahl T, Tveit KM, Johnson E, Kure EH, Vogel LK (2011)
    The level of claudin-7 is reduced as an early event in colorectal carcinogenesis
    BMC Cancer, 11, 65
    DOI 10.1186/1471-2407-11-65, PubMed 21310043
  2. Hammerman PS, Sos ML, Ramos AH, Xu C, Dutt A, Zhou W, Brace LE, Woods BA, Lin W, Zhang J, Deng X, Lim SM, Heynck S, Peifer M, Simard JR, Lawrence MS, Onofrio RC, Salvesen HB, Seidel D, Zander T, Heuckmann JM, Soltermann A, Moch H, Koker M, Leenders F et al. (2011)
    Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer
    Cancer Discov, 1 (1), 78-89
    DOI 10.1158/2159-8274.CD-11-0005, PubMed 22328973
  3. Helland Å, Anglesio MS, George J, Cowin PA, Johnstone CN, House CM, Sheppard KE, Etemadmoghadam D, Melnyk N, Rustgi AK, Phillips WA, Johnsen H, Holm R, Kristensen GB, Birrer MJ, Australian Ovarian Cancer Study Group, Pearson RB, Børresen-Dale AL, Huntsman DG, deFazio A, Creighton CJ, Smyth GK, Bowtell DD (2011)
    Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers
    PLoS One, 6 (4), e18064
    DOI 10.1371/journal.pone.0018064, PubMed 21533284
  4. Helland Å, Skaug HM, Kleinberg L, Iversen ML, Rud AK, Fleischer T, Sagerup C, Solberg S, Jørgensen L, Ariansen S, Brustugun OT (2011)
    EGFR gene alterations in a Norwegian cohort of lung cancer patients selected for surgery
    J Thorac Oncol, 6 (5), 947-50
    DOI 10.1097/JTO.0b013e31820db209, PubMed 21623266
  5. Haakensen VD, Bjøro T, Lüders T, Riis M, Bukholm IK, Kristensen VN, Troester MA, Homen MM, Ursin G, Børresen-Dale AL, Helland Å (2011)
    Serum estradiol levels associated with specific gene expression patterns in normal breast tissue and in breast carcinomas
    BMC Cancer, 11, 332
    DOI 10.1186/1471-2407-11-332, PubMed 21812955
  6. Haakensen VD, Lingjaerde OC, Lüders T, Riis M, Prat A, Troester MA, Holmen MM, Frantzen JO, Romundstad L, Navjord D, Bukholm IK, Johannesen TB, Perou CM, Ursin G, Kristensen VN, Børresen-Dale AL, Helland A (2011)
    Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features
    BMC Med Genomics, 4, 77
    DOI 10.1186/1755-8794-4-77, PubMed 22044755
  7. Kristensen VN, Vaske CJ, Ursini-Siegel J, Van Loo P, Nordgard SH, Sachidanandam R, Sørlie T, Wärnberg F, Haakensen VD, Helland Å, Naume B, Perou CM, Haussler D, Troyanskaya OG, Børresen-Dale AL (2011)
    Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling
    Proc Natl Acad Sci U S A, 109 (8), 2802-7
    DOI 10.1073/pnas.1108781108, PubMed 21908711
  8. Marcos NT, Bennett EP, Gomes J, Magalhaes A, Gomes C, David L, Dar I, Jeanneau C, DeFrees S, Krustrup D, Vogel LK, Kure EH, Burchell J, Taylor-Papadimitriou J, Clausen H, Mandel U, Reis CA (2011)
    ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues
    Front Biosci (Elite Ed), 3 (4), 1443-55
    DOI 10.2741/e345, PubMed 21622148
  9. Turzer M, Brustugun OT, Waldeland E, Helland A (2011)
    Stereotactic body radiation therapy is effective and safe in patients with early-stage non-small cell lung cancer with low performance status and severe comorbidity
    Case Rep Oncol, 4 (1), 25-34
    DOI 10.1159/000324113, PubMed 21526003

Publications 2010

  1. Haakensen VD, Biong M, Lingjærde OC, Holmen MM, Frantzen JO, Chen Y, Navjord D, Romundstad L, Lüders T, Bukholm IK, Solvang HK, Kristensen VN, Ursin G, Børresen-Dale AL, Helland A (2010)
    Expression levels of uridine 5'-diphospho-glucuronosyltransferase genes in breast tissue from healthy women are associated with mammographic density
    Breast Cancer Res, 12 (4), R65
    DOI 10.1186/bcr2632, PubMed 20799965
  2. Marienhagen K, Helland A, Nordberg T, Guren MG, Hofsli E (2010)
    [How do Norwegian oncologists perceive their working conditions?]
    Tidsskr Nor Laegeforen, 130 (5), 487-9
    DOI 10.4045/tidsskr.08.0305, PubMed 20224615
  3. Turzer M, Brustugun OT, Helland A (2010)
    Excessive Soft Tissue Reaction after Stereotactic Body Radiation Therapy in a Woman with Four Different Cancer Diagnoses
    Case Rep Oncol, 3 (2), 195-201
    DOI 10.1159/000317104, PubMed 20740196

Publications 2009

  1. Andersen V, Agerstjerne L, Jensen D, Østergaard M, Saebø M, Hamfjord J, Kure E, Vogel U (2009)
    The multidrug resistance 1 (MDR1) gene polymorphism G-rs3789243-A is not associated with disease susceptibility in Norwegian patients with colorectal adenoma and colorectal cancer; a case control study
    BMC Med Genet, 10, 18
    DOI 10.1186/1471-2350-10-18, PubMed 19250544
  2. Hansteen IL, Lågeide L, Clausen KO, Haugan V, Svendsen M, Eriksen JG, Skiaker R, Hauger E, Vistnes AI, Kure EH (2009)
    Cytogenetic effects of 18.0 and 16.5 GHz microwave radiation on human lymphocytes in vitro
    Anticancer Res, 29 (8), 2885-92
    PubMed 19661291
  3. Kamalakaran S, Kendall J, Zhao X, Tang C, Khan S, Ravi K, Auletta T, Riggs M, Wang Y, Helland A, Naume B, Dimitrova N, Børresen-Dale AL, Hicks J, Lucito R (2009)
    Methylation detection oligonucleotide microarray analysis: a high-resolution method for detection of CpG island methylation
    Nucleic Acids Res, 37 (12), e89
    DOI 10.1093/nar/gkp413, PubMed 19474344
  4. Klug SJ, Ressing M, Koenig J, Abba MC, Agorastos T, Brenna SM, Ciotti M, Das BR, Del Mistro A, Dybikowska A, Giuliano AR, Gudleviciene Z, Gyllensten U, Haws AL, Helland A, Herrington CS, Hildesheim A, Humbey O, Jee SH, Kim JW, Madeleine MM, Menczer J, Ngan HY, Nishikawa A, Niwa Y et al. (2009)
    TP53 codon 72 polymorphism and cervical cancer: a pooled analysis of individual data from 49 studies
    Lancet Oncol, 10 (8), 772-84
    DOI 10.1016/S1470-2045(09)70187-1, PubMed 19625214
  5. Murph MM, Liu W, Yu S, Lu Y, Hall H, Hennessy BT, Lahad J, Schaner M, Helland A, Kristensen G, Børresen-Dale AL, Mills GB (2009)
    Lysophosphatidic acid-induced transcriptional profile represents serous epithelial ovarian carcinoma and worsened prognosis
    PLoS One, 4 (5), e5583
    DOI 10.1371/journal.pone.0005583, PubMed 19440550
  6. Potapenko IO, Haakensen VD, Lüders T, Helland A, Bukholm I, Sørlie T, Kristensen VN, Lingjaerde OC, Børresen-Dale AL (2009)
    Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression
    Mol Oncol, 4 (2), 98-118
    DOI 10.1016/j.molonc.2009.12.001, PubMed 20060370
  7. Selzer-Plon J, Bornholdt J, Friis S, Bisgaard HC, Lothe IM, Tveit KM, Kure EH, Vogel U, Vogel LK (2009)
    Expression of prostasin and its inhibitors during colorectal cancer carcinogenesis
    BMC Cancer, 9, 201
    DOI 10.1186/1471-2407-9-201, PubMed 19555470
  8. Skovbjerg H, Anthonsen D, Lothe IM, Tveit KM, Kure EH, Vogel LK (2009)
    Collagen mRNA levels changes during colorectal cancer carcinogenesis
    BMC Cancer, 9, 136
    DOI 10.1186/1471-2407-9-136, PubMed 19422682

Publications 2008

  1. Saebø M, Skjelbred CF, Brekke Li K, Bowitz Lothe IM, Hagen PC, Johnsen E, Tveit KM, Kure EH (2008)
    CYP1A2 164 A-->C polymorphism, cigarette smoking, consumption of well-done red meat and risk of developing colorectal adenomas and carcinomas
    Anticancer Res, 28 (4C), 2289-95
    PubMed 18751408
  2. Aavitsland P, Helland A (2008)
    [The selected contagions]
    Tidsskr Nor Laegeforen, 128 (20), 2304
    PubMed 19096483

Publications 2007

  1. Davidson B, Skrede M, Silins I, Shih IeM, Trope CG, Flørenes VA (2007)
    Low-molecular weight forms of cyclin E differentiate ovarian carcinoma from cells of mesothelial origin and are associated with poor survival in ovarian carcinoma
    Cancer, 110 (6), 1264-71
    DOI 10.1002/cncr.22918, PubMed 17647260
  2. Edvardsen H, Kristensen VN, Grenaker Alnaes GI, Bøhn M, Erikstein B, Helland A, Børresen-Dale AL, Fosså SD (2007)
    Germline glutathione S-transferase variants in breast cancer: relation to diagnosis and cutaneous long-term adverse effects after two fractionation patterns of radiotherapy
    Int J Radiat Oncol Biol Phys, 67 (4), 1163-71
    DOI 10.1016/j.ijrobp.2006.11.009, PubMed 17336217
  3. Lorentzen A, Vogel LK, Lewinsky RH, Saebø M, Skjelbred CF, Godiksen S, Hoff G, Tveit KM, Lothe IM, Ikdahl T, Kure EH, Mitchelmore C (2007)
    Expression of NDRG2 is down-regulated in high-risk adenomas and colorectal carcinoma
    BMC Cancer, 7, 192
    DOI 10.1186/1471-2407-7-192, PubMed 17935612
  4. Sikkeland LI, Haug T, Stangeland AM, Flatberg G, Søstrand P, Halvorsen B, Kongerud J (2007)
    Airway inflammation in paper mill workers
    J Occup Environ Med, 49 (10), 1135-42
    DOI 10.1097/JOM.0b013e31814b2e87, PubMed 18000418
  5. Sikkeland LI, Kongerud J, Stangeland AM, Haug T, Alexis NE (2007)
    Macrophage enrichment from induced sputum
    Thorax, 62 (6), 558-9
    DOI 10.1136/thx.2006.073544, PubMed 17536036
  6. Skjelbred CF, Saebø M, Hjartåker A, Grotmol T, Hansteen IL, Tveit KM, Hoff G, Kure EH (2007)
    Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and adenomas
    BMC Cancer, 7, 228
    DOI 10.1186/1471-2407-7-228, PubMed 18093316

Publications 2006

  1. Chi JT, Wang Z, Nuyten DS, Rodriguez EH, Schaner ME, Salim A, Wang Y, Kristensen GB, Helland A, Børresen-Dale AL, Giaccia A, Longaker MT, Hastie T, Yang GP, van de Vijver MJ, Brown PO (2006)
    Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers
    PLoS Med, 3 (3), e47
    DOI 10.1371/journal.pmed.0030047, PubMed 16417408
  2. Drageset V, Nesland JM, Erikstein B, Skovlund E, Sommer H, Anker G, Wist E, Lundgren S, Bergh J, Kvalheim G (2006)
    Monitoring of disseminated tumor cells in bone marrow in high-risk breast cancer patients treated with high-dose chemotherapy
    Int J Cancer, 118 (11), 2877-81
    DOI 10.1002/ijc.21709, PubMed 16381016
  3. Helland A, Johnsen H, Frøyland C, Landmark HB, Saetersdal AB, Holmen MM, Gjertsen T, Nesland JM, Ottestad W, Jeffrey SS, Ottestad LO, Rodningen OK, Sherlock G, Børresen-Dale AL (2006)
    Radiation-induced effects on gene expression: an in vivo study on breast cancer
    Radiother Oncol, 80 (2), 230-5
    DOI 10.1016/j.radonc.2006.07.007, PubMed 16890317
  4. Rzyman W, Hagen OM, Dziadziuszko R, Kobierska-Gulida G, Karmolinski A, Lothe IM, Babovic A, Murawski M, Paleczka W, Jastrzebski T, Kopacz A, Jassem J, Lass P, Skokowski J (2006)
    Intraoperative, radio-guided sentinel lymph node mapping in 110 nonsmall cell lung cancer patients
    Ann Thorac Surg, 82 (1), 237-42
    DOI 10.1016/j.athoracsur.2006.01.094, PubMed 16798221
  5. Saebø M, Skjelbred CF, Nexø BA, Wallin H, Hansteen IL, Vogel U, Kure EH (2006)
    Increased mRNA expression levels of ERCC1, OGG1 and RAI in colorectal adenomas and carcinomas
    BMC Cancer, 6, 208
    DOI 10.1186/1471-2407-6-208, PubMed 16914027
  6. Sarebø M, Skjelbred CF, Breistein R, Lothe IM, Hagen PC, Bock G, Hansteen IL, Kure EH (2006)
    Association between cigarette smoking, APC mutations and the risk of developing sporadic colorectal adenomas and carcinomas
    BMC Cancer, 6, 71
    DOI 10.1186/1471-2407-6-71, PubMed 16545110
  7. Skjelbred CF, Saebø M, Nexø BA, Wallin H, Hansteen IL, Vogel U, Kure EH (2006)
    Effects of polymorphisms in ERCC1, ASE-1 and RAI on the risk of colorectal carcinomas and adenomas: a case control study
    BMC Cancer, 6, 175
    DOI 10.1186/1471-2407-6-175, PubMed 16817948
  8. Skjelbred CF, Saebø M, Wallin H, Nexø BA, Hagen PC, Lothe IM, Aase S, Johnson E, Hansteen IL, Vogel U, Kure EH (2006)
    Polymorphisms of the XRCC1, XRCC3 and XPD genes and risk of colorectal adenoma and carcinoma, in a Norwegian cohort: a case control study
    BMC Cancer, 6, 67
    DOI 10.1186/1471-2407-6-67, PubMed 16542436
  9. Stormorken AT, Hoff G, Norstein J, Bowitz-Lothe IM, Hanslien E, Grindedal E, Møller P (2006)
    Estimated prevalence of hereditary cancers and the need for surveillance in a Norwegian county, Telemark
    Scand J Gastroenterol, 41 (1), 71-9
    DOI 10.1080/00365520510023891, PubMed 16373279
  10. Vogel LK, Saebø M, Skjelbred CF, Abell K, Pedersen ED, Vogel U, Kure EH (2006)
    The ratio of Matriptase/HAI-1 mRNA is higher in colorectal cancer adenomas and carcinomas than corresponding tissue from control individuals
    BMC Cancer, 6, 176
    DOI 10.1186/1471-2407-6-176, PubMed 16820046

Publications 2005

  1. Hansen R, Saebø M, Skjelbred CF, Nexø BA, Hagen PC, Bock G, Bowitz Lothe IM, Johnson E, Aase S, Hansteen IL, Vogel U, Kure EH (2005)
    GPX Pro198Leu and OGG1 Ser326Cys polymorphisms and risk of development of colorectal adenomas and colorectal cancer
    Cancer Lett, 229 (1), 85-91
    DOI 10.1016/j.canlet.2005.04.019, PubMed 15946795
  2. Stormorken AT, Bowitz-Lothe IM, Norèn T, Kure E, Aase S, Wijnen J, Apold J, Heimdal K, Møller P (2005)
    Immunohistochemistry identifies carriers of mismatch repair gene defects causing hereditary nonpolyposis colorectal cancer
    J Clin Oncol, 23 (21), 4705-12
    DOI 10.1200/JCO.2005.05.180, PubMed 16034045
  3. Wang Y, Helland A, Holm R, Kristensen GB, Børresen-Dale AL (2005)
    PIK3CA mutations in advanced ovarian carcinomas
    Hum Mutat, 25 (3), 322
    DOI 10.1002/humu.9316, PubMed 15712344
  4. Wang Y, Kristensen GB, Helland A, Nesland JM, Børresen-Dale AL, Holm R (2005)
    Protein expression and prognostic value of genes in the erb-b signaling pathway in advanced ovarian carcinomas
    Am J Clin Pathol, 124 (3), 392-401
    DOI 10.1309/BL7E-MW66-LQX6-GFRP, PubMed 16191507

Publications 2004

  1. Soucek P, Skjelbred CF, Svendsen M, Kristensen T, Kure EH, Kristensen VN (2004)
    Single-track sequencing for genotyping of multiple SNPs in the N-acetyltransferase 1 (NAT1) gene
    BMC Biotechnol, 4, 28
    DOI 10.1186/1472-6750-4-28, PubMed 15563733
  2. Wang Y, Kringen P, Kristensen GB, Holm R, Baekelandt MM, Olivier M, Skomedal H, Hainaut P, Tropé CG, Abeler VM, Nesland JM, Børresen-Dale AL, Helland A (2004)
    Effect of the codon 72 polymorphism (c.215G>C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma
    Hum Mutat, 24 (1), 21-34
    DOI 10.1002/humu.20055, PubMed 15221786

Publications 2003

  1. Kristiansen M, Helland A, Kristensen GB, Olsen AO, Lønning PE, Børresen-Dale AL, Ørstavik KH (2003)
    X chromosome inactivation in cervical cancer patients
    Cancer Genet Cytogenet, 146 (1), 73-6
    DOI 10.1016/s0165-4608(03)00152-3, PubMed 14499700
  2. Stormorken AT, Müller W, Lindblom A, Heimdal K, Aase S, Lothe IM, Norèn T, Wijnen JT, Möslein G, Møller P (2003)
    The inframe MSH2 codon 596 deletion is linked with HNPCC and associated with lack of MSH2 protein in tumours
    Fam Cancer, 2 (1), 9-13
    DOI 10.1023/a:1023362205205, PubMed 14574162

Publications 2001

  1. Kristensen VN, Kure EH, Erikstein B, Harada N, Børresen-Dale A (2001)
    Genetic susceptibility and environmental estrogen-like compounds
    Mutat Res, 482 (1-2), 77-82
    DOI 10.1016/s0027-5107(01)00212-3, PubMed 11535251

Publications 2000

  1. Skaug V, Ryberg D, Kure EH, Arab MO, Stangeland L, Myking AO, Haugen A (2000)
    p53 mutations in defined structural and functional domains are related to poor clinical outcome in non-small cell lung cancer patients
    Clin Cancer Res, 6 (3), 1031-7
    PubMed 10741731

Publications 1997

  1. Hollstein M, Bartsch H, Wesch H, Kure EH, Mustonen R, Mühlbauer KR, Spiethoff A, Wegener K, Wiethege T, Müller KM (1997)
    p53 gene mutation analysis in tumors of patients exposed to alpha-particles
    Carcinogenesis, 18 (3), 511-6
    DOI 10.1093/carcin/18.3.511, PubMed 9067550

Publications 1996

  1. Andreassen A, Kure EH, Nielsen PS, Autrup H, Haugen A (1996)
    Comparative synchronous fluorescence spectrophotometry and 32P-postlabeling analysis of PAH-DNA adducts in human lung and the relationship to TP53 mutations
    Mutat Res, 368 (3-4), 275-82
    DOI 10.1016/s0165-1218(96)90069-5, PubMed 8692233

Publications 1995

  1. Ovrebø S, Fjeldstad PE, Grzybowska E, Kure EH, Chorazy M, Haugen A (1995)
    Biological monitoring of polycyclic aromatic hydrocarbon exposure in a highly polluted area of Poland
    Environ Health Perspect, 103 (9), 838-43
    DOI 10.1289/ehp.103-1519226, PubMed 7498096

Publications 1994

  1. Ryberg D, Kure E, Lystad S, Skaug V, Stangeland L, Mercy I, Børresen AL, Haugen A (1994)
    p53 mutations in lung tumors: relationship to putative susceptibility markers for cancer
    Cancer Res, 54 (6), 1551-5
    PubMed 8137262

Publications 1991

  1. Rappaport SM, Kure E, Petreas M, Ting D, Woodlee J (1991)
    A field method for measuring solvent vapors in exhaled air--application to styrene exposure
    Scand J Work Environ Health, 17 (3), 195-204
    DOI 10.5271/sjweh.1710, PubMed 2068559