Cathrine Knetter Hoel

  • Department engineer; PhD
  • +47 22 78 13 23


2010 → Post doctor. Institute of Cancer Research, Department of Immunology, Oslo University Hospital.


2004-2010    Philosophiae doctor (PhD), Department of Cancer Research and Molecular Medicine, NTNU, Trondheim, Norway.
Title of thesis: "Mechanisms of toll-like receptor 9 activation"
2002-2004 Cand.Scient./M.Sc. in Biotechnology, NTNU, Trondheim, Norway.
Title of thesis: "Studies of signaling and species-specific responses to CpG via Toll-like receptor 9".
2001-2002 Courses, NTNU. 
1998-2001 Bioingeniør, Sør-Trøndelag University College, HiST.

Scientific Publications

  • 5 publications in international scientific journals
  • 7 posters presented at international scientific conventions

Publications 2010

Nguyen TT, Johnsen IB, Knetter CF, Drabløs F, Fitzgerald KA, Lien E, Anthonsen MW (2010)
Differential gene expression downstream of Toll-like receptors (TLRs): role of c-Src and activating transcription factor 3 (ATF3)
J Biol Chem, 285 (22), 17011-9
DOI 10.1074/jbc.M109.068817, PubMed 20351107

Publications 2008

Bartholomeu DC, Ropert C, Melo MB, Parroche P, Junqueira CF, Teixeira SM, Sirois C, Kasperkovitz P, Knetter CF, Lien E, Latz E, Golenbock DT, Gazzinelli RT (2008)
Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi
J Immunol, 181 (2), 1333-44
DOI 10.4049/jimmunol.181.2.1333, PubMed 18606688

Publications 2004

Latz E, Schoenemeyer A, Visintin A, Fitzgerald KA, Monks BG, Knetter CF, Lien E, Nilsen NJ, Espevik T, Golenbock DT (2004)
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
Nat Immunol, 5 (2), 190-8
DOI 10.1038/ni1028, PubMed 14716310

Nilsen N, Nonstad U, Khan N, Knetter CF, Akira S, Sundan A, Espevik T, Lien E (2004)
Lipopolysaccharide and double-stranded RNA up-regulate toll-like receptor 2 independently of myeloid differentiation factor 88
J Biol Chem, 279 (38), 39727-35
DOI 10.1074/jbc.M405027200, PubMed 15190057

Publications 2003

Kandimalla ER, Bhagat L, Zhu FG, Yu D, Cong YP, Wang D, Tang JX, Tang JY, Knetter CF, Lien E, Agrawal S (2003)
A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif
Proc Natl Acad Sci U S A, 100 (24), 14303-8
DOI 10.1073/pnas.2335947100, PubMed 14610275

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