Cathrine Knetter Hoel
- Department engineer; PhD
- +47 22 78 13 23
|2010 →||Post doctor. Institute of Cancer Research, Department of Immunology, Oslo University Hospital.|
|2004-2010||Philosophiae doctor (PhD), Department of Cancer Research and Molecular Medicine, NTNU, Trondheim, Norway.
Title of thesis: "Mechanisms of toll-like receptor 9 activation"
|2002-2004||Cand.Scient./M.Sc. in Biotechnology, NTNU, Trondheim, Norway.
Title of thesis: "Studies of signaling and species-specific responses to CpG via Toll-like receptor 9".
|1998-2001||Bioingeniør, Sør-Trøndelag University College, HiST.|
- 5 publications in international scientific journals
- 7 posters presented at international scientific conventions
Differential gene expression downstream of Toll-like receptors (TLRs): role of c-Src and activating transcription factor 3 (ATF3)
J Biol Chem, 285 (22), 17011-9
DOI 10.1074/jbc.M109.068817, PubMed 20351107
Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi
J Immunol, 181 (2), 1333-44
DOI 10.4049/jimmunol.181.2.1333, PubMed 18606688
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
Nat Immunol, 5 (2), 190-8
DOI 10.1038/ni1028, PubMed 14716310
Lipopolysaccharide and double-stranded RNA up-regulate toll-like receptor 2 independently of myeloid differentiation factor 88
J Biol Chem, 279 (38), 39727-35
DOI 10.1074/jbc.M405027200, PubMed 15190057
A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif
Proc Natl Acad Sci U S A, 100 (24), 14303-8
DOI 10.1073/pnas.2335947100, PubMed 14610275