Publicatons

Publications published since 2008 from OUS - Norwegian PSC Research Center

239 publications found

Publications 2019

  1. Dhillon AK, Kremer AE, Kummen M, Boberg KM, Elferink RPO, Karlsen TH, Beuers U, Vesterhus M, Hov JR (2019)
    Autotaxin activity predicts transplant-free survival in primary sclerosing cholangitis
    Sci Rep, 9 (1), 8450
    DOI 10.1038/s41598-019-44762-7, PubMed 31186435
  2. Goode EC, Clark AB, Mells GF, Srivastava B, Spiess K, Gelson WTH, Trivedi PJ, Lynch KD, Castren E, Vesterhus MN, Karlsen TH, Ji SG, Anderson CA, Thorburn D, Hudson M, Heneghan MA, Aldersley MA, Bathgate A, Sandford RN, Alexander GJ, Chapman RW, Walmsley M, UK-PSC Consortium, Hirschfield GM, Rushbrook SM (2019)
    Factors Associated With Outcomes of Patients With Primary Sclerosing Cholangitis and Development and Validation of a Risk Scoring System
    Hepatology, 69 (5), 2120-2135
    DOI 10.1002/hep.30479, PubMed 30566748
  3. Jørgensen SF, Holm K, Macpherson ME, Storm-Larsen C, Kummen M, Fevang B, Aukrust P, Hov JR (2019)
    Selective IgA deficiency in humans is associated with reduced gut microbial diversity
    J Allergy Clin Immunol, 143 (5), 1969-1971.e11
    DOI 10.1016/j.jaci.2019.01.019, PubMed 30707969
  4. Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B (2019)
    Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
    Sci Rep, 9 (1), 167
    DOI 10.1038/s41598-018-35367-7, PubMed 30655568
  5. Karlsen TH, Newsome PN (2019)
    The dawn of a new EASL - A new chapter in the history of the European Association for the Study of the liver
    J Hepatol, 71 (1), 5-8
    DOI 10.1016/j.jhep.2019.03.010, PubMed 31056366
  6. Kummen M, Hov JR (2019)
    The gut microbial influence on cholestatic liver disease
    Liver Int (in press)
    DOI 10.1111/liv.14153, PubMed 31125502
  7. Mayerhofer CCK, Awoyemi A, Hov JR, Trøseid M, Broch K (2019)
    Reply: Potential risk associated with direct modulation of the gut flora in patients with heart failure
    ESC Heart Fail, 6 (3), 557-558
    DOI 10.1002/ehf2.12437, PubMed 31034162
  8. Mazzawi T, Hausken T, Hov JR, Valeur J, Sangnes DA, El-Salhy M, Gilja OH, Hatlebakk JG, Lied GA (2019)
    Clinical response to fecal microbiota transplantation in patients with diarrhea-predominant irritable bowel syndrome is associated with normalization of fecal microbiota composition and short-chain fatty acid levels
    Scand J Gastroenterol, 1-10 (in press)
    DOI 10.1080/00365521.2019.1624815, PubMed 31190584
  9. Mjelle AB, Mulabecirovic A, Havre RF, Rosendahl K, Juliusson PB, Olafsdottir E, Gilja OH, Vesterhus M (2019)
    Normal Liver Stiffness Values in Children: A Comparison of Three Different Elastography Methods
    J Pediatr Gastroenterol Nutr, 68 (5), 706-712
    DOI 10.1097/MPG.0000000000002320, PubMed 30889132
  10. Saffioti F, Roccarina D, Vesterhus M, Hov JR, Rosenberg W, Pinzani M, Pereira SP, Boberg KM, Thorburn D (2019)
    Cholangiocarcinoma is associated with a raised enhanced liver fibrosis score independent of primary sclerosing cholangitis
    Eur J Clin Invest, 49 (5), e13088
    DOI 10.1111/eci.13088, PubMed 30762236
  11. Schneditz G, Elias JE, Pagano E, Zaeem Cader M, Saveljeva S, Long K, Mukhopadhyay S, Arasteh M, Lawley TD, Dougan G, Bassett A, Karlsen TH, Kaser A, Kaneider NC (2019)
    GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump
    Sci Signal, 12 (562)
    DOI 10.1126/scisignal.aau9048, PubMed 30600262
  12. Syse VL, Brekke M, Grimsrud MM, Persett PS, Heyerdahl F, Hovda KE, Vallersnes OM (2019)
    Gender differences in acute recreational drug toxicity: a case series from Oslo, Norway
    BMC Emerg Med, 19 (1), 29
    DOI 10.1186/s12873-019-0244-3, PubMed 31035940
  13. Tysoe OC, Justin AW, Brevini T, Chen SE, Mahbubani KT, Frank AK, Zedira H, Melum E, Saeb-Parsy K, Markaki AE, Vallier L, Sampaziotis F (2019)
    Isolation and propagation of primary human cholangiocyte organoids for the generation of bioengineered biliary tissue
    Nat Protoc, 14 (6), 1884-1925
    DOI 10.1038/s41596-019-0168-0, PubMed 31110298

Publications 2018

  1. Arnbjerg CJ, Vestad B, Hov JR, Pedersen KK, Jespersen S, Johannesen HH, Holm K, Halvorsen B, Fallentin E, Hansen AE, Lange T, Kjær A, Trøseid M, Fischer BM, Nielsen SD (2018)
    Effect of Lactobacillus rhamnosus GG Supplementation on Intestinal Inflammation Assessed by PET/MRI Scans and Gut Microbiota Composition in HIV-Infected Individuals
    J Acquir Immune Defic Syndr, 78 (4), 450-457
    DOI 10.1097/QAI.0000000000001693, PubMed 29874201
  2. Berntsen NL, Fosby B, Tan C, Reims HM, Ogaard J, Jiang X, Schrumpf E, Valestrand L, Karlsen TH, Line PD, Blumberg RS, Melum E (2018)
    Natural killer T cells mediate inflammation in the bile ducts
    Mucosal Immunol, 11 (6), 1582-1590
    DOI 10.1038/s41385-018-0066-8, PubMed 30115993
  3. Broce I, Karch CM, Wen N, Fan CC, Wang Y, Tan CH, Kouri N, Ross OA, Höglinger GU, Muller U, Hardy J, International FTD-Genomics Consortium, Momeni P, Hess CP, Dillon WP, Miller ZA, Bonham LW, Rabinovici GD, Rosen HJ, Schellenberg GD, Franke A, Karlsen TH, Veldink JH, Ferrari R, Yokoyama JS et al. (2018)
    Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
    PLoS Med, 15 (1), e1002487
    DOI 10.1371/journal.pmed.1002487, PubMed 29315334
  4. Chung BK, Henriksen EKK, Jørgensen KK, Karlsen TH, Hirschfield GM, Liaskou E (2018)
    Gut and Liver B Cells of Common Clonal Origin in Primary Sclerosing Cholangitis-Inflammatory Bowel Disease
    Hepatol Commun, 2 (8), 956-967
    DOI 10.1002/hep4.1200, PubMed 30094406
  5. Colombo M, Karlsen TH (2018)
    The EASL International Liver Foundation: A growing pup with missions that are distinct yet integrated with those of its mother
    J Hepatol, 70 (3), 339-342
    DOI 10.1016/j.jhep.2018.11.017, PubMed 30577976
  6. Dhillon AK, Kummen M, Trøseid M, Åkra S, Liaskou E, Moum B, Vesterhus M, Karlsen TH, Seljeflot I, Hov JR (2018)
    Circulating markers of gut barrier function associated with disease severity in primary sclerosing cholangitis
    Liver Int, 39 (2), 371-381
    DOI 10.1111/liv.13979, PubMed 30269440
  7. Eaton JE, Vesterhus M, McCauley BM, Atkinson EJ, Schlicht EM, Juran BD, Gossard AA, LaRusso NF, Gores GJ, Karlsen TH, Lazaridis KN (2018)
    Primary Sclerosing Cholangitis Risk Estimate Tool (PREsTo) Predicts Outcomes of the Disease: A Derivation and Validation Study Using Machine Learning
    Hepatology (in press)
    DOI 10.1002/hep.30085, PubMed 29742811
  8. Hoel H, Hove-Skovsgaard M, Hov JR, Gaardbo JC, Holm K, Kummen M, Rudi K, Nwosu F, Valeur J, Gelpi M, Seljeflot I, Ueland PM, Gerstoft J, Ullum H, Aukrust P, Nielsen SD, Trøseid M (2018)
    Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction
    Sci Rep, 8 (1), 6725
    DOI 10.1038/s41598-018-25168-3, PubMed 29712976
  9. Holmer M, Melum E, Isoniemi H, Ericzon BG, Castedal M, Nordin A, Aagaard Schultz N, Rasmussen A, Line PD, Stål P, Bennet W, Hagström H (2018)
    Nonalcoholic fatty liver disease is an increasing indication for liver transplantation in the Nordic countries
    Liver Int, 38 (11), 2082-2090
    DOI 10.1111/liv.13751, PubMed 29630771
  10. Karlsen TH, Tacke F (2018)
    «The times they are a'changin'» - Positioning the European Association for the Study of the Liver in the changing landscape of hepatology
    J Hepatol, 68 (5), 873-875
    DOI 10.1016/j.jhep.2018.02.001, PubMed 29500035
  11. Kummen M, Mayerhofer CCK, Vestad B, Broch K, Awoyemi A, Storm-Larsen C, Ueland T, Yndestad A, Hov JR, Trøseid M (2018)
    Gut Microbiota Signature in Heart Failure Defined From Profiling of 2 Independent Cohorts
    J Am Coll Cardiol, 71 (10), 1184-1186
    DOI 10.1016/j.jacc.2017.12.057, PubMed 29519360
  12. Lindström L, Jørgensen KK, Boberg KM, Castedal M, Rasmussen A, Rostved AA, Isoniemi H, Bottai M, Bergquist A (2018)
    Risk factors and prognosis for recurrent primary sclerosing cholangitis after liver transplantation: a Nordic Multicentre Study
    Scand J Gastroenterol, 53 (3), 297-304
    DOI 10.1080/00365521.2017.1421705, PubMed 29301479
  13. Lunder AK, Bakstad LT, Jahnsen J, Borthne A, Hov JR, Vatn M, Negård A, IBSEN Study (2018)
    Assessment of Bowel Inflammation and Strictures by Magnetic Resonance Enterography in Long-term Crohn´s Disease
    J Crohns Colitis, 13 (5), 607-614
    DOI 10.1093/ecco-jcc/jjy208, PubMed 30541145
  14. Maroni L, Pinto C, Giordano DM, Saccomanno S, Banales JM, Spallacci D, Albertini MC, Orlando F, Provinciali M, Milkiewicz M, Melum E, Labiano I, Milkiewicz P, Rychlicki C, Trozzi L, Scarpelli M, Benedetti A, Svegliati Baroni G, Marzioni M (2018)
    Aging-Related Expression of Twinfilin-1 Regulates Cholangiocyte Biological Response to Injury
    Hepatology (in press)
    DOI 10.1002/hep.30466, PubMed 30561764
  15. Mayerhofer CCK, Awoyemi AO, Moscavitch SD, Lappegård KT, Hov JR, Aukrust P, Hovland A, Lorenzo A, Halvorsen S, Seljeflot I, Gullestad L, Trøseid M, Broch K (2018)
    Design of the GutHeart-targeting gut microbiota to treat heart failure-trial: a Phase II, randomized clinical trial
    ESC Heart Fail, 5 (5), 977-984
    DOI 10.1002/ehf2.12332, PubMed 30088346
  16. Mazzawi T, Lied GA, Sangnes DA, El-Salhy M, Hov JR, Gilja OH, Hatlebakk JG, Hausken T (2018)
    The kinetics of gut microbial community composition in patients with irritable bowel syndrome following fecal microbiota transplantation
    PLoS One, 13 (11), e0194904
    DOI 10.1371/journal.pone.0194904, PubMed 30427836
  17. Momozawa Y, Dmitrieva J, Théâtre E, Deffontaine V, Rahmouni S, Charloteaux B, Crins F, Docampo E, Elansary M, Gori AS, Lecut C, Mariman R, Mni M, Oury C, Altukhov I, Alexeev D, Aulchenko Y, Amininejad L, Bouma G, Hoentjen F, Löwenberg M, Oldenburg B, Pierik MJ, Vander Meulen-de Jong AE, Janneke van der Woude C et al. (2018)
    IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
    Nat Commun, 9 (1), 2427
    DOI 10.1038/s41467-018-04365-8, PubMed 29930244
  18. Mulabecirovic A, Mjelle AB, Gilja OH, Vesterhus M, Havre RF (2018)
    Liver elasticity in healthy individuals by two novel shear-wave elastography systems-Comparison by age, gender, BMI and number of measurements
    PLoS One, 13 (9), e0203486
    DOI 10.1371/journal.pone.0203486, PubMed 30216377
  19. Mulabecirovic A, Mjelle AB, Gilja OH, Vesterhus M, Havre RF (2018)
    Repeatability of shear wave elastography in liver fibrosis phantoms-Evaluation of five different systems
    PLoS One, 13 (1), e0189671
    DOI 10.1371/journal.pone.0189671, PubMed 29293527
  20. Paquin-Proulx D, Greenspun BC, Pasquet L, Strunz B, Aleman S, Falconer K, Terabe M, Berzofsky JA, Sandberg JK, Melum E, Nixon DF, Björkström NK (2018)
    IL13Rα2 expression identifies tissue-resident IL-22-producing PLZF+ innate T cells in the human liver
    Eur J Immunol, 48 (8), 1329-1335
    DOI 10.1002/eji.201747334, PubMed 29677387
  21. Pihlstrøm HK, Mjøen G, Mucha S, Franke A, Jardine A, Fellström B, Dahle DO, Holdaas H, Melum E (2018)
    Genetic markers associated with long-term cardiovascular outcome in kidney transplant recipients
    Am J Transplant, 19 (5), 1444-1451
    DOI 10.1111/ajt.15191, PubMed 30457209
  22. Pollheimer MJ, Racedo S, Mikels-Vigdal A, Marshall D, Bowlus C, Lackner C, Madl T, Karlsen TH, Hov JR, Lyman SK, Adamkewicz J, Smith V, Moreau E, Zollner G, Eide TJ, Stojakovic T, Scharnagl H, Gruber HJ, Stauber RE, Trauner M, Fickert P (2018)
    Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis
    J Hepatol, 69 (2), 368-377
    DOI 10.1016/j.jhep.2018.04.009, PubMed 29709678
  23. Schmitt C, Lenglet H, Yu A, Delaby C, Benecke A, Lefebvre T, Letteron P, Paradis V, Wahlin S, Sandberg S, Harper P, Sardh E, Sandvik AK, Hov JR, Aarsand AK, Chiche L, Bazille C, Scoazec JY, To-Figueras J, Carrascal M, Abian J, Mirmiran A, Karim Z, Deybach JC, Puy H et al. (2018)
    Recurrent attacks of acute hepatic porphyria: major role of the chronic inflammatory response in the liver
    J Intern Med, 284 (1), 78-91
    DOI 10.1111/joim.12750, PubMed 29498764
  24. Schrumpf E, Rizvi SMH (2018)
    Pustular drug rash
    Tidsskr. Nor. Laegeforen., 138 (18), 1746
  25. Thorgersen EB, Melum E, Folseraas T, Larsen SG, Line PD (2018)
    Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei in a liver-transplanted patient: a case report
    World J Surg Oncol, 16 (1), 180
    DOI 10.1186/s12957-018-1482-7, PubMed 30185175
  26. Tronstad RR, Polushina T, Brattbakk HR, Stansberg C, von Volkmann HL, Hanevik K, Ellinghaus E, Jørgensen SF, Ersland KM, Pham KD, Gilja OH, Hovdenak N, Hausken T, Vatn MH, Franke A, Knappskog PM, Le Hellard S, Karlsen TH, Fiskerstrand T (2018)
    Genetic and transcriptional analysis of inflammatory bowel disease-associated pathways in patients with GUCY2C-linked familial diarrhea
    Scand J Gastroenterol, 53 (10-11), 1264-1273
    DOI 10.1080/00365521.2018.1521867, PubMed 30353760
  27. Åberg F, Isoniemi H, Pukkala E, Jalanko H, Rasmussen A, Storm HH, Schultz N, Bennet W, Ekvall N, Ericzon BG, Malenicka S, Tretli S, Line PD, Boberg KM, Østensen A, Karlsen TH, Nordin A (2018)
    Cancer After Liver Transplantation in Children and Young Adults: A Population-Based Study From 4 Nordic Countries
    Liver Transpl, 24 (9), 1252-1259
    DOI 10.1002/lt.25305, PubMed 30120902

Publications 2017

  1. Alberts R, de Vries EMG, Goode EC, Jiang X, Sampaziotis F, Rombouts K, Böttcher K, Folseraas T, Weismüller TJ, Mason AL, Wang W, Alexander G, Alvaro D, Bergquist A, Björkström NK, Beuers U, Björnsson E, Boberg KM, Bowlus CL, Bragazzi MC, Carbone M, Chazouillères O, Cheung A, Dalekos G, Eaton J et al. (2017)
    Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis
    Gut, 67 (8), 1517-1524
    DOI 10.1136/gutjnl-2016-313598, PubMed 28779025
  2. Bende F, Mulabecirovic A, Sporea I, Popescu A, Sirli R, Gilja OH, Vesterhus M, Havre RF (2017)
    Assessing Liver Stiffness by 2-D Shear Wave Elastography in a Healthy Cohort
    Ultrasound Med Biol, 44 (2), 332-341
    DOI 10.1016/j.ultrasmedbio.2017.10.013, PubMed 29249457
  3. Berntsen NL, Fosby B, Valestrand L, Tan C, Reims HM, Schrumpf E, Karlsen TH, Line PD, Melum E (2017)
    Establishment of a surgical bile duct injection technique giving direct access to the bile ducts for studies of the murine biliary tree
    Am J Physiol Gastrointest Liver Physiol, 314 (3), G349-G359
    DOI 10.1152/ajpgi.00124.2017, PubMed 29212771
  4. Carpino G, Cardinale V, Folseraas T, Overi D, Floreani A, Franchitto A, Onori P, Cazzagon N, Berloco PB, Karlsen TH, Alvaro D, Gaudio E (2017)
    Hepatic Stem/Progenitor Cell Activation Differs between Primary Sclerosing and Primary Biliary Cholangitis
    Am J Pathol, 188 (3), 627-639
    DOI 10.1016/j.ajpath.2017.11.010, PubMed 29248458
  5. Chung BK, Hirschfield GM (2017)
    Immunogenetics in primary sclerosing cholangitis
    Curr Opin Gastroenterol, 33 (2), 93-98
    DOI 10.1097/MOG.0000000000000336, PubMed 28146446
  6. Chung BK, Karlsen TH (2017)
    Genetic Discoveries Highlight Environmental Factors as Key Drivers of Liver Disease
    Dig Dis, 35 (4), 323-333
    DOI 10.1159/000456583, PubMed 28468012
  7. Chung BK, Karlsen TH, Folseraas T (2017)
    Cholangiocytes in the pathogenesis of primary sclerosing cholangitis and development of cholangiocarcinoma
    Biochim Biophys Acta Mol Basis Dis, 1864 (4 Pt B), 1390-1400
    DOI 10.1016/j.bbadis.2017.08.020, PubMed 28844951
  8. Claussen JC, Skiecevičienė J, Wang J, Rausch P, Karlsen TH, Lieb W, Baines JF, Franke A, Hütt MT (2017)
    Boolean analysis reveals systematic interactions among low-abundance species in the human gut microbiome
    PLoS Comput Biol, 13 (6), e1005361
    DOI 10.1371/journal.pcbi.1005361, PubMed 28640804
  9. de Muinck EJ, Trosvik P, Gilfillan GD, Hov JR, Sundaram AYM (2017)
    A novel ultra high-throughput 16S rRNA gene amplicon sequencing library preparation method for the Illumina HiSeq platform
    Microbiome, 5 (1), 68
    DOI 10.1186/s40168-017-0279-1, PubMed 28683838
  10. de Vries EMG, Färkkilä M, Milkiewicz P, Hov JR, Eksteen B, Thorburn D, Chazouillères O, Pares A, Nygård S, Gilja OH, Wunsch E, Invernizzi P, Carbone M, Bernuzzi F, Boberg KM, Røsjø H, Rosenberg W, Beuers UH, Ponsioen CY, Karlsen TH, Vesterhus M (2017)
    Enhanced liver fibrosis test predicts transplant-free survival in primary sclerosing cholangitis, a multi-centre study
    Liver Int, 37 (10), 1554-1561
    DOI 10.1111/liv.13402, PubMed 28267887
  11. Dueland S, Guren TK, Boberg KM, Reims HM, Grzyb K, Aamdal S, Julsrud L, Line PD (2017)
    Acute liver graft rejection after ipilimumab therapy
    Ann Oncol, 28 (10), 2619-2620
    DOI 10.1093/annonc/mdx281, PubMed 28961840
  12. Fickert P, Hirschfield GM, Denk G, Marschall HU, Altorjay I, Färkkilä M, Schramm C, Spengler U, Chapman R, Bergquist A, Schrumpf E, Nevens F, Trivedi P, Reiter FP, Tornai I, Halilbasic E, Greinwald R, Pröls M, Manns MP, Trauner M, European PSC norUDCA Study Group (2017)
    norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis
    J Hepatol, 67 (3), 549-558
    DOI 10.1016/j.jhep.2017.05.009, PubMed 28529147
  13. Haissman JM, Haugaard AK, Ostrowski SR, Berge RK, Hov JR, Trøseid M, Nielsen SD (2017)
    Microbiota-dependent metabolite and cardiovascular disease marker trimethylamine-N-oxide (TMAO) is associated with monocyte activation but not platelet function in untreated HIV infection
    BMC Infect Dis, 17 (1), 445
    DOI 10.1186/s12879-017-2547-x, PubMed 28645263
  14. Henriksen EKK, Viken MK, Wittig M, Holm K, Folseraas T, Mucha S, Melum E, Hov JR, Lazaridis KN, Juran BD, Chazouillères O, Färkkilä M, Gotthardt DN, Invernizzi P, Carbone M, Hirschfield GM, Rushbrook SM, Goode E, UK-PSC Consortium, Ponsioen CY, Weersma RK, Eksteen B, Yimam KK, Gordon SC, Goldberg D et al. (2017)
    HLA haplotypes in primary sclerosing cholangitis patients of admixed and non-European ancestry
    HLA, 90 (4), 228-233
    DOI 10.1111/tan.13076, PubMed 28695657
  15. Hov JR, Karlsen TH (2017)
    The Microbiome in Primary Sclerosing Cholangitis: Current Evidence and Potential Concepts
    Semin Liver Dis, 37 (4), 314-331
    DOI 10.1055/s-0037-1608801, PubMed 29272894
  16. Hov JR, Kummen M (2017)
    Intestinal microbiota in primary sclerosing cholangitis
    Curr Opin Gastroenterol, 33 (2), 85-92
    DOI 10.1097/MOG.0000000000000334, PubMed 28030369
  17. Jahnsen FL, Bækkevold ES, Hov JR, Landsverk OJ (2017)
    Do Long-Lived Plasma Cells Maintain a Healthy Microbiota in the Gut?
    Trends Immunol, 39 (3), 196-208
    DOI 10.1016/j.it.2017.10.006, PubMed 29162322
  18. Jiang X, Björkström NK, Melum E (2017)
    Intact CD100-CD72 Interaction Necessary for TCR-Induced T Cell Proliferation
    Front Immunol, 8, 765
    DOI 10.3389/fimmu.2017.00765, PubMed 28713384
  19. Jiang X, Karlsen TH (2017)
    Genetics of primary sclerosing cholangitis and pathophysiological implications
    Nat Rev Gastroenterol Hepatol, 14 (5), 279-295
    DOI 10.1038/nrgastro.2016.154, PubMed 28293027
  20. Karlsen TH, Folseraas T, Thorburn D, Vesterhus M (2017)
    Primary sclerosing cholangitis - a comprehensive review
    J Hepatol, 67 (6), 1298-1323
    DOI 10.1016/j.jhep.2017.07.022, PubMed 28802875
  21. Koch M, Freitag-Wolf S, Schlesinger S, Borggrefe J, Hov JR, Jensen MK, Pick J, Markus MRP, Höpfner T, Jacobs G, Siegert S, Artati A, Kastenmüller G, Römisch-Margl W, Adamski J, Illig T, Nothnagel M, Karlsen TH, Schreiber S, Franke A, Krawczak M, Nöthlings U, Lieb W (2017)
    Serum metabolomic profiling highlights pathways associated with liver fat content in a general population sample
    Eur J Clin Nutr, 71 (8), 995-1001
    DOI 10.1038/ejcn.2017.43, PubMed 28378853
  22. Landskron J, Kraggerud SM, Wik E, Dørum A, Bjørnslett M, Melum E, Helland Ø, Bjørge L, Lothe RA, Salvesen HB, Taskén K (2017)
    C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease
    PLoS One, 12 (7), e0182030
    DOI 10.1371/journal.pone.0182030, PubMed 28759630
  23. Lunder AK, Jahnsen J, Bakstad LT, Borthne A, Hov JR, Vatn M, Negård A, IBSEN Study Group (2017)
    Bowel Damage in Patients With Long-term Crohn's Disease, Assessed by Magnetic Resonance Enterography and the Lémann Index
    Clin Gastroenterol Hepatol, 16 (1), 75-82.e5
    DOI 10.1016/j.cgh.2017.06.053, PubMed 28694130
  24. Maroni L, Hohenester SD, van de Graaf SFJ, Tolenaars D, van Lienden K, Verheij J, Marzioni M, Karlsen TH, Oude Elferink RPJ, Beuers U (2017)
    Knockout of the primary sclerosing cholangitis-risk gene Fut2 causes liver disease in mice
    Hepatology, 66 (2), 542-554
    DOI 10.1002/hep.29029, PubMed 28056490
  25. Mayerhofer CCK, Ueland T, Broch K, Vincent RP, Cross GF, Dahl CP, Aukrust P, Gullestad L, Hov JR, Trøseid M (2017)
    Increased Secondary/Primary Bile Acid Ratio in Chronic Heart Failure
    J Card Fail, 23 (9), 666-671
    DOI 10.1016/j.cardfail.2017.06.007, PubMed 28688889
  26. Meijerink H, White RA, Løvlie A, de Blasio BF, Dalgard O, Amundsen EJ, Melum E, Kløvstad H (2017)
    Modelling the burden of hepatitis C infection among people who inject drugs in Norway, 1973-2030
    BMC Infect Dis, 17 (1), 541
    DOI 10.1186/s12879-017-2631-2, PubMed 28774261
  27. Nordin A, Åberg F, Pukkala E, Pedersen CR, Storm HH, Rasmussen A, Bennet W, Olausson M, Wilczek H, Ericzon BG, Tretli S, Line PD, Karlsen TH, Boberg KM, Isoniemi H (2017)
    Decreasing incidence of cancer after liver transplantation-A Nordic population-based study over 3 decades
    Am J Transplant, 18 (4), 952-963
    DOI 10.1111/ajt.14507, PubMed 28925583
  28. O'Hara SP, Karlsen TH, LaRusso NF (2017)
    Cholangiocytes and the environment in primary sclerosing cholangitis: where is the link?
    Gut, 66 (11), 1873-1877
    DOI 10.1136/gutjnl-2017-314249, PubMed 28733279
  29. Rosati E, Dowds CM, Liaskou E, Henriksen EKK, Karlsen TH, Franke A (2017)
    Overview of methodologies for T-cell receptor repertoire analysis
    BMC Biotechnol, 17 (1), 61
    DOI 10.1186/s12896-017-0379-9, PubMed 28693542
  30. Rühlemann MC, Degenhardt F, Thingholm LB, Wang J, Skiecevičienė J, Rausch P, Hov JR, Lieb W, Karlsen TH, Laudes M, Baines JF, Heinsen FA, Franke A (2017)
    Application of the distance-based F test in an mGWAS investigating β diversity of intestinal microbiota identifies variants in SLC9A8 (NHE8) and 3 other loci
    Gut Microbes, 9 (1), 68-75
    DOI 10.1080/19490976.2017.1356979, PubMed 28816579
  31. Sampaziotis F, Justin AW, Tysoe OC, Sawiak S, Godfrey EM, Upponi SS, Gieseck RL, de Brito MC, Berntsen NL, Gómez-Vázquez MJ, Ortmann D, Yiangou L, Ross A, Bargehr J, Bertero A, Zonneveld MCF, Pedersen MT, Pawlowski M, Valestrand L, Madrigal P, Georgakopoulos N, Pirmadjid N, Skeldon GM, Casey J, Shu W et al. (2017)
    Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids
    Nat Med, 23 (8), 954-963
    DOI 10.1038/nm.4360, PubMed 28671689
  32. Schrumpf E, Jiang X, Zeissig S, Pollheimer MJ, Anmarkrud JA, Tan C, Exley MA, Karlsen TH, Blumberg RS, Melum E (2017)
    The role of natural killer T cells in a mouse model with spontaneous bile duct inflammation
    Physiol Rep, 5 (4)
    DOI 10.14814/phy2.13117, PubMed 28219981
  33. Trivedi PJ, Tickle J, Vesterhus MN, Eddowes PJ, Bruns T, Vainio J, Parker R, Smith D, Liaskou E, Thorbjørnsen LW, Hirschfield GM, Auvinen K, Hubscher SG, Salmi M, Adams DH, Weston CJ (2017)
    Vascular adhesion protein-1 is elevated in primary sclerosing cholangitis, is predictive of clinical outcome and facilitates recruitment of gut-tropic lymphocytes to liver in a substrate-dependent manner
    Gut, 67 (6), 1135-1145
    DOI 10.1136/gutjnl-2016-312354, PubMed 28428344
  34. Tronstad RR, Kummen M, Holm K, von Volkmann HL, Anmarkrud JA, Høivik ML, Moum B, Gilja OH, Hausken T, Baines J, Karlsen TH, Fiskerstrand T, Hov JR (2017)
    Guanylate Cyclase C Activation Shapes the Intestinal Microbiota in Patients with Familial Diarrhea and Increased Susceptibility for Crohn's Disease
    Inflamm Bowel Dis, 23 (10), 1752-1761
    DOI 10.1097/MIB.0000000000001264, PubMed 28902124
  35. Vesterhus M, Holm A, Hov JR, Nygård S, Schrumpf E, Melum E, Thorbjørnsen LW, Paulsen V, Lundin K, Dale I, Gilja OH, Zweers SJLB, Vatn M, Schaap FG, Jansen PLM, Ueland T, Røsjø H, Moum B, Ponsioen CY, Boberg KM, Färkkilä M, Karlsen TH, Lund-Johansen F (2017)
    Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis
    J Hepatol, 66 (6), 1214-1222
    DOI 10.1016/j.jhep.2017.01.019, PubMed 28161472
  36. Volkmann ER, Hoffmann-Vold AM, Chang YL, Jacobs JP, Tillisch K, Mayer EA, Clements PJ, Hov JR, Kummen M, Midtvedt Ø, Lagishetty V, Chang L, Labus JS, Molberg Ø, Braun J (2017)
    Systemic sclerosis is associated with specific alterations in gastrointestinal microbiota in two independent cohorts
    BMJ Open Gastroenterol, 4 (1), e000134
    DOI 10.1136/bmjgast-2017-000134, PubMed 28761687
  37. Weismüller TJ, Trivedi PJ, Bergquist A, Imam M, Lenzen H, Ponsioen CY, Holm K, Gotthardt D, Färkkilä MA, Marschall HU, Thorburn D, Weersma RK, Fevery J, Mueller T, Chazouillères O, Schulze K, Lazaridis KN, Almer S, Pereira SP, Levy C, Mason A, Naess S, Bowlus CL, Floreani A, Halilbasic E et al. (2017)
    Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis
    Gastroenterology, 152 (8), 1975-1984.e8
    DOI 10.1053/j.gastro.2017.02.038, PubMed 28274849
  38. Witoelar A, Jansen IE, Wang Y, Desikan RS, Gibbs JR, Blauwendraat C, Thompson WK, Hernandez DG, Djurovic S, Schork AJ, Bettella F, Ellinghaus D, Franke A, Lie BA, McEvoy LK, Karlsen TH, Lesage S, Morris HR, Brice A, Wood NW, Heutink P, Hardy J, Singleton AB, Dale AM, Gasser T et al. (2017)
    Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases
    JAMA Neurol, 74 (7), 780-792
    DOI 10.1001/jamaneurol.2017.0469, PubMed 28586827
  39. Aabakken L, Karlsen TH, Albert J, Arvanitakis M, Chazouilleres O, Dumonceau JM, Färkkilä M, Fickert P, Hirschfield GM, Laghi A, Marzioni M, Fernandez M, Pereira SP, Pohl J, Poley JW, Ponsioen CY, Schramm C, Swahn F, Tringali A, Hassan C (2017)
    Role of endoscopy in primary sclerosing cholangitis: European Society of Gastrointestinal Endoscopy (ESGE) and European Association for the Study of the Liver (EASL) Clinical Guideline
    Endoscopy, 49 (6), 588-608
    DOI 10.1055/s-0043-107029, PubMed 28420030

Publications 2016

  1. Banales JM, Cardinale V, Carpino G, Marzioni M, Andersen JB, Invernizzi P, Lind GE, Folseraas T, Forbes SJ, Fouassier L, Geier A, Calvisi DF, Mertens JC, Trauner M, Benedetti A, Maroni L, Vaquero J, Macias RI, Raggi C, Perugorria MJ, Gaudio E, Boberg KM, Marin JJ, Alvaro D (2016)
    Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)
    Nat Rev Gastroenterol Hepatol, 13 (5), 261-80
    DOI 10.1038/nrgastro.2016.51, PubMed 27095655
  2. Bernuzzi F, Marabita F, Lleo A, Carbone M, Mirolo M, Marzioni M, Alpini G, Alvaro D, Boberg KM, Locati M, Torzilli G, Rimassa L, Piscaglia F, He XS, Bowlus CL, Yang GX, Gershwin ME, Invernizzi P (2016)
    Serum microRNAs as novel biomarkers for primary sclerosing cholangitis and cholangiocarcinoma
    Clin Exp Immunol, 185 (1), 61-71
    DOI 10.1111/cei.12776, PubMed 26864161
  3. Chung BK, Guevel BT, Reynolds GM, Gupta Udatha DB, Henriksen EK, Stamataki Z, Hirschfield GM, Karlsen TH, Liaskou E (2016)
    Phenotyping and auto-antibody production by liver-infiltrating B cells in primary sclerosing cholangitis and primary biliary cholangitis
    J Autoimmun, 77, 45-54
    DOI 10.1016/j.jaut.2016.10.003, PubMed 27784538
  4. Ellinghaus D, Jostins L, Spain SL, Cortes A, Bethune J, Han B, Park YR, Raychaudhuri S, Pouget JG, Hübenthal M, Folseraas T, Wang Y, Esko T, Metspalu A, Westra HJ, Franke L, Pers TH, Weersma RK, Collij V, D'Amato M, Halfvarson J, Jensen AB, Lieb W, Degenhardt F, Forstner AJ et al. (2016)
    Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
    Nat Genet, 48 (5), 510-8
    DOI 10.1038/ng.3528, PubMed 26974007
  5. Gabrielsen IS, Amundsen SS, Helgeland H, Flåm ST, Hatinoor N, Holm K, Viken MK, Lie BA (2016)
    Genetic risk variants for autoimmune diseases that influence gene expression in thymus
    Hum Mol Genet, 25 (14), 3117-3124
    DOI 10.1093/hmg/ddw152, PubMed 27199374
  6. Gabrielsen IS, Viken MK, Amundsen SS, Helgeland H, Holm K, Flåm ST, Lie BA (2016)
    Autoimmune risk variants in ERAP2 are associated with gene-expression levels in thymus
    Genes Immun, 17 (7), 406-411
    DOI 10.1038/gene.2016.39, PubMed 27829666
  7. Henriksen EK, Jørgensen KK, Kaveh F, Holm K, Hamm D, Olweus J, Melum E, Chung BK, Eide TJ, Lundin KE, Boberg KM, Karlsen TH, Hirschfield GM, Liaskou E (2016)
    Gut and liver T-cells of common clonal origin in primary sclerosing cholangitis-inflammatory bowel disease
    J Hepatol, 66 (1), 116-122
    DOI 10.1016/j.jhep.2016.09.002, PubMed 27647428
  8. Hov JR, Boberg KM, Taraldsrud E, Vesterhus M, Boyadzhieva M, Solberg IC, Schrumpf E, Vatn MH, Lie BA, Molberg Ø, Karlsen TH (2016)
    Antineutrophil antibodies define clinical and genetic subgroups in primary sclerosing cholangitis
    Liver Int, 37 (3), 458-465
    DOI 10.1111/liv.13238, PubMed 27558072
  9. Jendrek ST, Gotthardt D, Nitzsche T, Widmann L, Korf T, Michaels MA, Weiss KH, Liaskou E, Vesterhus M, Karlsen TH, Mindorf S, Schemmer P, Bär F, Teegen B, Schröder T, Ehlers M, Hammers CM, Komorowski L, Lehnert H, Fellermann K, Derer S, Hov JR, Sina C (2016)
    Anti-GP2 IgA autoantibodies are associated with poor survival and cholangiocarcinoma in primary sclerosing cholangitis
    Gut, 66 (1), 137-144
    DOI 10.1136/gutjnl-2016-311739, PubMed 27406039
  10. Ji SG, Juran BD, Mucha S, Folseraas T, Jostins L, Melum E, Kumasaka N, Atkinson EJ, Schlicht EM, Liu JZ, Shah T, Gutierrez-Achury J, Boberg KM, Bergquist A, Vermeire S, Eksteen B, Durie PR, Farkkila M, Müller T, Schramm C, Sterneck M, Weismüller TJ, Gotthardt DN, Ellinghaus D, Braun F et al. (2016)
    Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease
    Nat Genet, 49 (2), 269-273
    DOI 10.1038/ng.3745, PubMed 27992413
  11. Jørgensen SF, Macpherson ME, Bjøro K, Karlsen TH, Reims HM, Grzyb K, Fosby B, Fevang B, Aukrust P, Nordøy I (2016)
    Liver transplantation in patients with primary antibody deficiency
    J Allergy Clin Immunol, 139 (5), 1708-1710.e2
    DOI 10.1016/j.jaci.2016.10.025, PubMed 27931972
  12. Jørgensen SF, Reims HM, Frydenlund D, Holm K, Paulsen V, Michelsen AE, Jørgensen KK, Osnes LT, Bratlie J, Eide TJ, Dahl CP, Holter E, Tronstad RR, Hanevik K, Brattbakk HR, Kaveh F, Fiskerstrand T, Kran AB, Ueland T, Karlsen TH, Aukrust P, Lundin KE, Fevang B (2016)
    A Cross-Sectional Study of the Prevalence of Gastrointestinal Symptoms and Pathology in Patients With Common Variable Immunodeficiency
    Am J Gastroenterol, 111 (10), 1467-1475
    DOI 10.1038/ajg.2016.329, PubMed 27527747
  13. Jørgensen SF, Trøseid M, Kummen M, Anmarkrud JA, Michelsen AE, Osnes LT, Holm K, Høivik ML, Rashidi A, Dahl CP, Vesterhus M, Halvorsen B, Mollnes TE, Berge RK, Moum B, Lundin KE, Fevang B, Ueland T, Karlsen TH, Aukrust P, Hov JR (2016)
    Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation
    Mucosal Immunol, 9 (6), 1455-1465
    DOI 10.1038/mi.2016.18, PubMed 26982597
  14. Karlsen TH (2016)
    Primary sclerosing cholangitis: 50 years of a gut-liver relationship and still no love?
    Gut, 65 (10), 1579-81
    DOI 10.1136/gutjnl-2016-312137, PubMed 27402486
  15. Knudsen A, Christensen TE, Thorsteinsson K, Ghotbi AA, Hasbak P, Lebech AM, Nielsen SD, Hov JR, Berge R, Ripa RS, Kjær A, Trøseid M (2016)
    Microbiota-Dependent Marker TMAO is Not Associated With Decreased Myocardial Perfusion in Well-Treated HIV-Infected Patients as Assessed by 82Rubidium PET/CT
    J Acquir Immune Defic Syndr, 72 (4), e83-5
    DOI 10.1097/QAI.0000000000001044, PubMed 27152465
  16. Kummen M, Holm K, Anmarkrud JA, Nygård S, Vesterhus M, Høivik ML, Trøseid M, Marschall HU, Schrumpf E, Moum B, Røsjø H, Aukrust P, Karlsen TH, Hov JR (2016)
    The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls
    Gut, 66 (4), 611-619
    DOI 10.1136/gutjnl-2015-310500, PubMed 26887816
  17. Kummen M, Hov JR (2016)
    Response to 'Faecal microbiota profiles as diagnostic biomarkers in primary sclerosing cholangitis' by Rühlemann et al
    Gut, 66 (4), 755-756
    DOI 10.1136/gutjnl-2016-312347, PubMed 27340191
  18. Kummen M, Vesterhus M, Trøseid M, Moum B, Svardal A, Boberg KM, Aukrust P, Karlsen TH, Berge RK, Hov JR (2016)
    Elevated trimethylamine-N-oxide (TMAO) is associated with poor prognosis in primary sclerosing cholangitis patients with normal liver function
    United European Gastroenterol J, 5 (4), 532-541
    DOI 10.1177/2050640616663453, PubMed 28588885
  19. Lunder AK, Hov JR, Borthne A, Gleditsch J, Johannesen G, Tveit K, Viktil E, Henriksen M, Hovde Ø, Huppertz-Hauss G, Høie O, Høivik ML, Monstad I, Solberg IC, Jahnsen J, Karlsen TH, Moum B, Vatn M, Negård A (2016)
    Prevalence of Sclerosing Cholangitis Detected by Magnetic Resonance Cholangiography in Patients With Long-term Inflammatory Bowel Disease
    Gastroenterology, 151 (4), 660-669.e4
    DOI 10.1053/j.gastro.2016.06.021, PubMed 27342213
  20. Maroni L, Agostinelli L, Saccomanno S, Pinto C, Giordano DM, Rychlicki C, De Minicis S, Trozzi L, Banales JM, Melum E, Karlsen TH, Benedetti A, Baroni GS, Marzioni M (2016)
    Nlrp3 Activation Induces Il-18 Synthesis and Affects the Epithelial Barrier Function in Reactive Cholangiocytes
    Am J Pathol, 187 (2), 366-376
    DOI 10.1016/j.ajpath.2016.10.010, PubMed 27912077
  21. Mjelle AB, Mulabecirovic A, Hausken T, Havre RF, Gilja OH, Vesterhus M (2016)
    Ultrasound and Point Shear Wave Elastography in Livers of Patients with Primary Sclerosing Cholangitis
    Ultrasound Med Biol, 42 (9), 2146-55
    DOI 10.1016/j.ultrasmedbio.2016.04.016, PubMed 27262519
  22. Mulabecirovic A, Vesterhus M, Gilja OH, Havre RF (2016)
    In Vitro Comparison of Five Different Elastography Systems for Clinical Applications, Using Strain and Shear Wave Technology
    Ultrasound Med Biol, 42 (11), 2572-2588
    DOI 10.1016/j.ultrasmedbio.2016.07.002, PubMed 27570209
  23. Pihlstrøm HK, Mjøen G, Mucha S, Haraldsen G, Franke A, Jardine A, Fellström B, Holdaas H, Melum E (2016)
    Single Nucleotide Polymorphisms and Long-Term Clinical Outcome in Renal Transplant Patients: A Validation Study
    Am J Transplant, 17 (2), 528-533
    DOI 10.1111/ajt.13995, PubMed 27483393
  24. Schrumpf E, Kummen M, Valestrand L, Greiner TU, Holm K, Arulampalam V, Reims HM, Baines J, Bäckhed F, Karlsen TH, Blumberg RS, Hov JR, Melum E (2016)
    The gut microbiota contributes to a mouse model of spontaneous bile duct inflammation
    J Hepatol, 66 (2), 382-389
    DOI 10.1016/j.jhep.2016.09.020, PubMed 27720803
  25. Skagen K, Trøseid M, Ueland T, Holm S, Abbas A, Gregersen I, Kummen M, Bjerkeli V, Reier-Nilsen F, Russell D, Svardal A, Karlsen TH, Aukrust P, Berge RK, Hov JE, Halvorsen B, Skjelland M (2016)
    The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis
    Atherosclerosis, 247, 64-9
    DOI 10.1016/j.atherosclerosis.2016.01.033, PubMed 26868510
  26. Saadati HR, Wittig M, Helbig I, Häsler R, Anderson CA, Mathew CG, Kupcinskas L, Parkes M, Karlsen TH, Rosenstiel P, Schreiber S, Franke A (2016)
    Genome-wide rare copy number variation screening in ulcerative colitis identifies potential susceptibility loci
    BMC Med Genet, 17, 26
    DOI 10.1186/s12881-016-0289-z, PubMed 27037036
  27. Trøseid M, Hov JR, Nestvold TK, Thoresen H, Berge RK, Svardal A, Lappegård KT (2016)
    Major Increase in Microbiota-Dependent Proatherogenic Metabolite TMAO One Year After Bariatric Surgery
    Metab Syndr Relat Disord, 14 (4), 197-201
    DOI 10.1089/met.2015.0120, PubMed 27081744
  28. Vesterhus M, Melum E (2016)
    Prognostic biomarkers and surrogate end points in PSC
    Liver Int, 36 (12), 1748-1751
    DOI 10.1111/liv.13216, PubMed 27864874
  29. Wang J, Thingholm LB, Skiecevičienė J, Rausch P, Kummen M, Hov JR, Degenhardt F, Heinsen FA, Rühlemann MC, Szymczak S, Holm K, Esko T, Sun J, Pricop-Jeckstadt M, Al-Dury S, Bohov P, Bethune J, Sommer F, Ellinghaus D, Berge RK, Hübenthal M, Koch M, Schwarz K, Rimbach G, Hübbe P et al. (2016)
    Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota
    Nat Genet, 48 (11), 1396-1406
    DOI 10.1038/ng.3695, PubMed 27723756
  30. Yokoyama JS, Wang Y, Schork AJ, Thompson WK, Karch CM, Cruchaga C, McEvoy LK, Witoelar A, Chen CH, Holland D, Brewer JB, Franke A, Dillon WP, Wilson DM, Mukherjee P, Hess CP, Miller Z, Bonham LW, Shen J, Rabinovici GD, Rosen HJ, Miller BL, Hyman BT, Schellenberg GD, Karlsen TH et al. (2016)
    Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease
    JAMA Neurol, 73 (6), 691-7
    DOI 10.1001/jamaneurol.2016.0150, PubMed 27088644
  31. Zenouzi R, Weismüller TJ, Jørgensen KK, Bubenheim M, Lenzen H, Hübener P, Schulze K, Weiler-Normann C, Sebode M, Ehlken H, Pannicke N, Hartl J, Peiseler M, Hübener S, Karlsen TH, Boberg KM, Manns MP, Lohse AW, Schramm C (2016)
    No Evidence That Azathioprine Increases Risk of Cholangiocarcinoma in Patients With Primary Sclerosing Cholangitis
    Clin Gastroenterol Hepatol, 14 (12), 1806-1812
    DOI 10.1016/j.cgh.2016.07.032, PubMed 27521513
  32. Zweers SJ, Shiryaev A, Komuta M, Vesterhus M, Hov JR, Perugorria MJ, de Waart DR, Chang JC, Tol S, Te Velde AA, de Jonge WJ, Banales JM, Roskams T, Beuers U, Karlsen TH, Jansen PL, Schaap FG (2016)
    Elevated interleukin-8 in bile of patients with primary sclerosing cholangitis
    Liver Int, 36 (9), 1370-7
    DOI 10.1111/liv.13092, PubMed 26866350

Publications 2015

  1. Andersen IM, Fosby B, Boberg KM, Clausen OP, Jebsen P, Melum E, Line PD, Foss A, Schrumpf E, Karlsen TH (2015)
    Indications and Outcomes in Liver Transplantation in Patients With Primary Sclerosing Cholangitis in Norway
    Transplant Direct, 1 (9), e39
    DOI 10.1097/TXD.0000000000000548, PubMed 27500239
  2. Andreassen OA, Desikan RS, Wang Y, Thompson WK, Schork AJ, Zuber V, Doncheva NT, Ellinghaus E, Albrecht M, Mattingsdal M, Franke A, Lie BA, Mills IG, Aukrust P, McEvoy LK, Djurovic S, Karlsen TH, Dale AM (2015)
    Correction: Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms
    PLoS One, 10 (5), e0128048
    DOI 10.1371/journal.pone.0128048, PubMed 25978331
  3. Andreassen OA, Desikan RS, Wang Y, Thompson WK, Schork AJ, Zuber V, Doncheva NT, Ellinghaus E, Albrecht M, Mattingsdal M, Franke A, Lie BA, Mills IG, Aukrust P, McEvoy LK, Djurovic S, Karlsen TH, Dale AM (2015)
    Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms
    PLoS One, 10 (4), e0123057
    DOI 10.1371/journal.pone.0123057, PubMed 25853426
  4. Andresen K, Boberg KM, Vedeld HM, Honne H, Jebsen P, Hektoen M, Wadsworth CA, Clausen OP, Lundin KE, Paulsen V, Foss A, Mathisen Ø, Aabakken L, Schrumpf E, Lothe RA, Lind GE (2015)
    Four DNA methylation biomarkers in biliary brush samples accurately identify the presence of cholangiocarcinoma
    Hepatology, 61 (5), 1651-9
    DOI 10.1002/hep.27707, PubMed 25644509
  5. Berntsen NL, Klingenberg O, Juran BD, Benito de Valle M, Lindkvist B, Lazaridis KN, Boberg KM, Karlsen TH, Hov JR (2015)
    Association Between HLA Haplotypes and Increased Serum Levels of IgG4 in Patients With Primary Sclerosing Cholangitis
    Gastroenterology, 148 (5), 924-927.e2
    DOI 10.1053/j.gastro.2015.01.041, PubMed 25655558
  6. Carpino G, Cardinale V, Renzi A, Hov JR, Berloco PB, Rossi M, Karlsen TH, Alvaro D, Gaudio E (2015)
    Activation of biliary tree stem cells within peribiliary glands in primary sclerosing cholangitis
    J Hepatol, 63 (5), 1220-8
    DOI 10.1016/j.jhep.2015.06.018, PubMed 26119688
  7. Cleynen I, Boucher G, Jostins L, Schumm LP, Zeissig S, Ahmad T, Andersen V, Andrews JM, Annese V, Brand S, Brant SR, Cho JH, Daly MJ, Dubinsky M, Duerr RH, Ferguson LR, Franke A, Gearry RB, Goyette P, Hakonarson H, Halfvarson J, Hov JR, Huang H, Kennedy NA, Kupcinskas L et al. (2015)
    Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
    Lancet, 387 (10014), 156-67
    DOI 10.1016/S0140-6736(15)00465-1, PubMed 26490195
  8. D'Agnolo HM, Kievit W, Andrade RJ, Karlsen TH, Wedemeyer H, Drenth JP (2015)
    Creating an effective clinical registry for rare diseases
    United European Gastroenterol J, 4 (3), 333-8
    DOI 10.1177/2050640615618042, PubMed 27403298
  9. Folseraas T, Boberg KM (2015)
    Cancer Risk and Surveillance in Primary Sclerosing Cholangitis
    Clin Liver Dis, 20 (1), 79-98
    DOI 10.1016/j.cld.2015.08.014, PubMed 26593292
  10. Folseraas T, Liaskou E, Anderson CA, Karlsen TH (2015)
    Genetics in PSC: what do the "risk genes" teach us?
    Clin Rev Allergy Immunol, 48 (2-3), 154-64
    DOI 10.1007/s12016-014-8417-z, PubMed 24736995
  11. Fosby B, Melum E, Bjøro K, Bennet W, Rasmussen A, Andersen IM, Castedal M, Olausson M, Wibeck C, Gotlieb M, Gjertsen H, Toivonen L, Foss S, Makisalo H, Nordin A, Sanengen T, Bergquist A, Larsson ME, Soderdahl G, Nowak G, Boberg KM, Isoniemi H, Keiding S, Foss A, Line PD et al. (2015)
    Liver transplantation in the Nordic countries - An intention to treat and post-transplant analysis from The Nordic Liver Transplant Registry 1982-2013
    Scand J Gastroenterol, 50 (6), 797-808
    DOI 10.3109/00365521.2015.1036359, PubMed 25959101
  12. Goyette P, Boucher G, Mallon D, Ellinghaus E, Jostins L, Huang H, Ripke S, Gusareva ES, Annese V, Hauser SL, Oksenberg JR, Thomsen I, Leslie S, International Inflammatory Bowel Disease Genetics Consortium, Australia and New Zealand IBDGC, Belgium IBD Genetics Consortium, Italian Group for IBD Genetic Consortium, NIDDK Inflammatory Bowel Disease Genetics Consortium, United Kingdom IBDGC, Wellcome Trust Case Control Consortium, Quebec IBD Genetics Consortium, Daly MJ, Van Steen K, Duerr RH, Barrett JC et al. (2015)
    High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis
    Nat Genet, 47 (2), 172-9
    DOI 10.1038/ng.3176, PubMed 25559196
  13. Hov JE, Trøseid M (2015)
    Personalised medicine targeting the gut microbiota?
    Tidsskr Nor Laegeforen, 135 (7), 624
    DOI 10.4045/tidsskr.14.1431, PubMed 25899345
  14. Hov JER, Troseid M (2015)
    Personalized intestinal flora medicine?
    Tidsskr. Nor. Laegeforen., 135 (7), 624
  15. Hov JR, Zhong H, Qin B, Anmarkrud JA, Holm K, Franke A, Lie BA, Karlsen TH (2015)
    The Influence of the Autoimmunity-Associated Ancestral HLA Haplotype AH8.1 on the Human Gut Microbiota: A Cross-Sectional Study
    PLoS One, 10 (7), e0133804
    DOI 10.1371/journal.pone.0133804, PubMed 26207384
  16. Karlsen TH, Chung BK (2015)
    Genetic Risk and the Development of Autoimmune Liver Disease
    Dig Dis, 33 Suppl 2, 13-24
    DOI 10.1159/000440706, PubMed 26641277
  17. Karlsen TH, Lammert F, Thompson RJ (2015)
    Genetics of liver disease: From pathophysiology to clinical practice
    J Hepatol, 62 (1 Suppl), S6-S14
    DOI 10.1016/j.jhep.2015.02.025, PubMed 25920091
  18. Kevans D, Tyler AD, Holm K, Jørgensen KK, Vatn MH, Karlsen TH, Kaplan GG, Eksteen B, Gevers D, Hov JR, Silverberg MS (2015)
    Characterization of Intestinal Microbiota in Ulcerative Colitis Patients with and without Primary Sclerosing Cholangitis
    J Crohns Colitis, 10 (3), 330-7
    DOI 10.1093/ecco-jcc/jjv204, PubMed 26526357
  19. Li J, Jørgensen SF, Maggadottir SM, Bakay M, Warnatz K, Glessner J, Pandey R, Salzer U, Schmidt RE, Perez E, Resnick E, Goldacker S, Buchta M, Witte T, Padyukov L, Videm V, Folseraas T, Atschekzei F, Elder JT, Nair RP, Winkelmann J, Gieger C, Nöthen MM, Büning C, Brand S et al. (2015)
    Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells
    Nat Commun, 6, 6804
    DOI 10.1038/ncomms7804, PubMed 25891430
  20. Liaskou E, Klemsdal Henriksen EK, Holm K, Kaveh F, Hamm D, Fear J, Viken MK, Hov JR, Melum E, Robins H, Olweus J, Karlsen TH, Hirschfield GM (2015)
    High-throughput T-cell receptor sequencing across chronic liver diseases reveals distinct disease-associated repertoires
    Hepatology, 63 (5), 1608-19
    DOI 10.1002/hep.28116, PubMed 26257205
  21. Olin P, Hausken J, Foss A, Karlsen TH, Melum E, Haugaa H (2015)
    Continuous molecular adsorbent recirculating system treatment in 69 patients listed for liver transplantation
    Scand J Gastroenterol, 50 (9), 1127-34
    DOI 10.3109/00365521.2015.1027262, PubMed 25865318
  22. Ponsioen CY, Chapman RW, Chazouillères O, Hirschfield GM, Karlsen TH, Lohse AW, Pinzani M, Schrumpf E, Trauner M, Gores GJ (2015)
    Surrogate endpoints for clinical trials in primary sclerosing cholangitis: Review and results from an International PSC Study Group consensus process
    Hepatology, 63 (4), 1357-67
    DOI 10.1002/hep.28256, PubMed 26418478
  23. Sampaziotis F, de Brito MC, Madrigal P, Bertero A, Saeb-Parsy K, Soares FAC, Schrumpf E, Melum E, Karlsen TH, Bradley JA, Gelson WT, Davies S, Baker A, Kaser A, Alexander GJ, Hannan NRF, Vallier L (2015)
    Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation
    Nat Biotechnol, 33 (8), 845-852
    DOI 10.1038/nbt.3275, PubMed 26167629
  24. Schrumpf E, Boberg KM, Karlsen TH (2015)
    Primary sclerosing cholangitis - the Norwegian experience
    Scand J Gastroenterol, 50 (6), 781-96
    DOI 10.3109/00365521.2015.1028996, PubMed 25866138
  25. Schrumpf E, Tan C, Karlsen TH, Sponheim J, Björkström NK, Sundnes O, Alfsnes K, Kaser A, Jefferson DM, Ueno Y, Eide TJ, Haraldsen G, Zeissig S, Exley MA, Blumberg RS, Melum E (2015)
    The biliary epithelium presents antigens to and activates natural killer T cells
    Hepatology, 62 (4), 1249-59
    DOI 10.1002/hep.27840, PubMed 25855031
  26. Stiksrud B, Nowak P, Nwosu FC, Kvale D, Thalme A, Sonnerborg A, Ueland PM, Holm K, Birkeland SE, Dahm AE, Sandset PM, Rudi K, Hov JR, Dyrhol-Riise AM, Trøseid M (2015)
    Reduced Levels of D-dimer and Changes in Gut Microbiota Composition After Probiotic Intervention in HIV-Infected Individuals on Stable ART
    J Acquir Immune Defic Syndr, 70 (4), 329-37
    DOI 10.1097/QAI.0000000000000784, PubMed 26258571
  27. Thorsen T, Dahlgren US, Aandahl EM, Grzyb K, Karlsen TH, Boberg KM, Rydberg L, Naper C, Foss A, Bennet W (2015)
    Liver transplantation with deceased ABO-incompatible donors is life-saving but associated with increased risk of rejection and post-transplant complications
    Transpl Int, 28 (7), 800-12
    DOI 10.1111/tri.12552, PubMed 25736519
  28. Thorsen T, Aandahl EM, Bennet W, Olausson M, Ericzon BG, Nowak G, Duraj F, Isoniemi H, Rasmussen A, Karlsen TH, Foss A (2015)
    Transplantation With Livers From Deceased Donors Older Than 75 Years
    Transplantation, 99 (12), 2534-42
    DOI 10.1097/TP.0000000000000728, PubMed 25909464
  29. Vesterhus M, Hov JR, Holm A, Schrumpf E, Nygård S, Godang K, Andersen IM, Naess S, Thorburn D, Saffioti F, Vatn M, Gilja OH, Lund-Johansen F, Syversveen T, Brabrand K, Parés A, Ponsioen CY, Pinzani M, Färkkilä M, Moum B, Ueland T, Røsjø H, Rosenberg W, Boberg KM, Karlsen TH (2015)
    Enhanced liver fibrosis score predicts transplant-free survival in primary sclerosing cholangitis
    Hepatology, 62 (1), 188-97
    DOI 10.1002/hep.27825, PubMed 25833813
  30. Vukcevic D, Traherne JA, Næss S, Ellinghaus E, Kamatani Y, Dilthey A, Lathrop M, Karlsen TH, Franke A, Moffatt M, Cookson W, Trowsdale J, McVean G, Sawcer S, Leslie S (2015)
    Imputation of KIR Types from SNP Variation Data
    Am J Hum Genet, 97 (4), 593-607
    DOI 10.1016/j.ajhg.2015.09.005, PubMed 26430804
  31. Wannhoff A, Folseraas T, Brune M, Rupp C, Friedrich K, Knierim J, Weiss KH, Sauer P, Flechtenmacher C, Schirmacher P, Stremmel W, Hov JR, Gotthardt DN (2015)
    A common genetic variant of fucosyltransferase 2 correlates with serum carcinoembryonic antigen levels and affects cancer screening in patients with primary sclerosing cholangitis
    United European Gastroenterol J, 4 (1), 84-91
    DOI 10.1177/2050640615581577, PubMed 26966527
  32. Wannhoff A, Rupp C, Friedrich K, Brune M, Knierim J, Flechtenmacher C, Sauer P, Stremmel W, Hov JR, Schirmacher P, Weiss KH, Gotthardt DN (2015)
    Inflammation But Not Biliary Obstruction Is Associated With Carbohydrate Antigen 19-9 Levels in Patients With Primary Sclerosing Cholangitis
    Clin Gastroenterol Hepatol, 13 (13), 2372-9
    DOI 10.1016/j.cgh.2015.07.014, PubMed 26192140
  33. Wittig M, Anmarkrud JA, Kässens JC, Koch S, Forster M, Ellinghaus E, Hov JR, Sauer S, Schimmler M, Ziemann M, Görg S, Jacob F, Karlsen TH, Franke A (2015)
    Development of a high-resolution NGS-based HLA-typing and analysis pipeline
    Nucleic Acids Res, 43 (11), e70
    DOI 10.1093/nar/gkv184, PubMed 25753671
  34. Åberg F, Gissler M, Karlsen TH, Ericzon BG, Foss A, Rasmussen A, Bennet W, Olausson M, Line PD, Nordin A, Bergquist A, Boberg KM, Castedal M, Pedersen CR, Isoniemi H (2015)
    Differences in long-term survival among liver transplant recipients and the general population: a population-based Nordic study
    Hepatology, 61 (2), 668-77
    DOI 10.1002/hep.27538, PubMed 25266201

Publications 2014

  1. Eskesen AN, Bjøro K, Aandahl EM, Line PD, Melum E (2014)
    Low use of surveillance and early diagnosis of hepatocellular carcinoma in Norway--a population-based cohort study
    Cancer Epidemiol, 38 (6), 741-7
    DOI 10.1016/j.canep.2014.10.005, PubMed 25454262
  2. Fickert P, Pollheimer MJ, Beuers U, Lackner C, Hirschfield G, Housset C, Keitel V, Schramm C, Marschall HU, Karlsen TH, Melum E, Kaser A, Eksteen B, Strazzabosco M, Manns M, Trauner M, International PSC Study Group (IPSCSG) (2014)
    Characterization of animal models for primary sclerosing cholangitis (PSC)
    J Hepatol, 60 (6), 1290-303
    DOI 10.1016/j.jhep.2014.02.006, PubMed 24560657
  3. Flachsbart F, Caliebe A, Heinsen FA, Hemming-Karlsen T, Schreiber S, Franke A, Nebel A (2014)
    Investigation of complement component C4 copy number variation in human longevity
    PLoS One, 9 (1), e86188
    DOI 10.1371/journal.pone.0086188, PubMed 24465950
  4. Fosby B, Næss S, Hov JR, Traherne J, Boberg KM, Trowsdale J, Foss A, Line PD, Franke A, Melum E, Scott H, Karlsen TH (2014)
    HLA variants related to primary sclerosing cholangitis influence rejection after liver transplantation
    World J Gastroenterol, 20 (14), 3986-4000
    DOI 10.3748/wjg.v20.i14.3986, PubMed 24744588
  5. Friedrich K, Wannhoff A, Kattner S, Brune M, Hov JR, Weiss KH, Antoni C, Dollinger M, Neumann-Haefelin C, Seufferlein T, Schemmer P, Schirmacher P, Stremmel W, Gotthardt DN (2014)
    PNPLA3 in end-stage liver disease: alcohol consumption, hepatocellular carcinoma development, and transplantation-free survival
    J Gastroenterol Hepatol, 29 (7), 1477-84
    DOI 10.1111/jgh.12540, PubMed 25273282
  6. Henriksen EK, Melum E, Karlsen TH (2014)
    Update on primary sclerosing cholangitis genetics
    Curr Opin Gastroenterol, 30 (3), 310-9
    DOI 10.1097/MOG.0000000000000052, PubMed 24565892
  7. Hirschfield GM, Karlsen TH (2014)
    Genetic risks link autoimmune hepatitis to other autoimmune liver disease
    Gastroenterology, 147 (2), 270-3
    DOI 10.1053/j.gastro.2014.06.020, PubMed 24973678
  8. Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, Pyzik M, Ostrowski MA, Glickman JN, Rudd CE, Ploegh HL, Franke A, Petsko GA, Kuchroo VK, Blumberg RS (2014)
    CEACAM1 regulates TIM-3-mediated tolerance and exhaustion
    Nature, 517 (7534), 386-90
    DOI 10.1038/nature13848, PubMed 25363763
  9. Naess S, Björnsson E, Anmarkrud JA, Al Mamari S, Juran BD, Lazaridis KN, Chapman R, Bergquist A, Melum E, Marsh SG, Schrumpf E, Lie BA, Boberg KM, Karlsen TH, Hov JR (2014)
    Small duct primary sclerosing cholangitis without inflammatory bowel disease is genetically different from large duct disease
    Liver Int, 34 (10), 1488-95
    DOI 10.1111/liv.12492, PubMed 24517468
  10. Næss S, Lie BA, Melum E, Olsson M, Hov JR, Croucher PJ, Hampe J, Thorsby E, Bergquist A, Traherne JA, Schrumpf E, Boberg KM, Schreiber S, Franke A, Karlsen TH (2014)
    Refinement of the MHC risk map in a scandinavian primary sclerosing cholangitis population
    PLoS One, 9 (12), e114486
    DOI 10.1371/journal.pone.0114486, PubMed 25521205
  11. Rupp C, Friedrich K, Folseraas T, Wannhoff A, Bode KA, Weiss KH, Schirmacher P, Sauer P, Stremmel W, Gotthardt DN (2014)
    Fut2 genotype is a risk factor for dominant stenosis and biliary candida infections in primary sclerosing cholangitis
    Aliment Pharmacol Ther, 39 (8), 873-82
    DOI 10.1111/apt.12663, PubMed 24612312
  12. Trøseid M, Ueland T, Hov JR, Svardal A, Gregersen I, Dahl CP, Aakhus S, Gude E, Bjørndal B, Halvorsen B, Karlsen TH, Aukrust P, Gullestad L, Berge RK, Yndestad A (2014)
    Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure
    J Intern Med, 277 (6), 717-26
    DOI 10.1111/joim.12328, PubMed 25382824
  13. Vedeld HM, Andresen K, Eilertsen IA, Nesbakken A, Seruca R, Gladhaug IP, Thiis-Evensen E, Rognum TO, Boberg KM, Lind GE (2014)
    The novel colorectal cancer biomarkers CDO1, ZSCAN18 and ZNF331 are frequently methylated across gastrointestinal cancers
    Int J Cancer, 136 (4), 844-53
    DOI 10.1002/ijc.29039, PubMed 24948044
  14. Zeissig S, Petersen BS, Tomczak M, Melum E, Huc-Claustre E, Dougan SK, Laerdahl JK, Stade B, Forster M, Schreiber S, Weir D, Leichtner AM, Franke A, Blumberg RS (2014)
    Early-onset Crohn's disease and autoimmunity associated with a variant in CTLA-4
    Gut, 64 (12), 1889-97
    DOI 10.1136/gutjnl-2014-308541, PubMed 25367873

Publications 2013

  1. Andersen IM, Tengesdal G, Lie BA, Boberg KM, Karlsen TH, Hov JR (2013)
    Effects of coffee consumption, smoking, and hormones on risk for primary sclerosing cholangitis
    Clin Gastroenterol Hepatol, 12 (6), 1019-28
    DOI 10.1016/j.cgh.2013.09.024, PubMed 24076415
  2. Block M, Jørgensen KK, Oresland T, Lindholm E, Grzyb K, Cvancarova M, Vatn MH, Boberg KM, Börjesson L (2013)
    Colectomy for patients with ulcerative colitis and primary sclerosing cholangitis - what next?
    J Crohns Colitis, 8 (5), 421-30
    DOI 10.1016/j.crohns.2013.10.008, PubMed 24239402
  3. Boberg KM, Wisløff T, Kjøllesdal KS, Støvring H, Kristiansen IS (2013)
    Cost and health consequences of treatment of primary biliary cirrhosis with ursodeoxycholic acid
    Aliment Pharmacol Ther, 38 (7), 794-803
    DOI 10.1111/apt.12435, PubMed 23915021
  4. Ellinghaus D, Folseraas T, Holm K, Ellinghaus E, Melum E, Balschun T, Laerdahl JK, Shiryaev A, Gotthardt DN, Weismüller TJ, Schramm C, Wittig M, Bergquist A, Björnsson E, Marschall HU, Vatn M, Teufel A, Rust C, Gieger C, Wichmann HE, Runz H, Sterneck M, Rupp C, Braun F, Weersma RK et al. (2013)
    Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4
    Hepatology, 58 (3), 1074-83
    DOI 10.1002/hep.25977, PubMed 22821403
  5. Ellinghaus D, Zhang H, Zeissig S, Lipinski S, Till A, Jiang T, Stade B, Bromberg Y, Ellinghaus E, Keller A, Rivas MA, Skieceviciene J, Doncheva NT, Liu X, Liu Q, Jiang F, Forster M, Mayr G, Albrecht M, Häsler R, Boehm BO, Goodall J, Berzuini CR, Lee J, Andersen V et al. (2013)
    Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies
    Gastroenterology, 145 (2), 339-47
    DOI 10.1053/j.gastro.2013.04.040, PubMed 23624108
  6. Friedrich K, Rupp C, Hov JR, Steinebrunner N, Weiss KH, Stiehl A, Brune M, Schaefer PK, Schemmer P, Sauer P, Schirmacher P, Runz H, Karlsen TH, Stremmel W, Gotthardt DN (2013)
    A frequent PNPLA3 variant is a sex specific disease modifier in PSC patients with bile duct stenosis
    PLoS One, 8 (3), e58734
    DOI 10.1371/journal.pone.0058734, PubMed 23505555
  7. Hagness M, Foss A, Line PD, Scholz T, Jørgensen PF, Fosby B, Boberg KM, Mathisen O, Gladhaug IP, Egge TS, Solberg S, Hausken J, Dueland S (2013)
    Liver transplantation for nonresectable liver metastases from colorectal cancer
    Ann Surg, 257 (5), 800-6
    DOI 10.1097/SLA.0b013e3182823957, PubMed 23360920
  8. Hirschfield GM, Karlsen TH, Lindor KD, Adams DH (2013)
    Primary sclerosing cholangitis
    Lancet, 382 (9904), 1587-99
    DOI 10.1016/S0140-6736(13)60096-3, PubMed 23810223
  9. Jørgensen KK, Lindström L, Cvancarova M, Karlsen TH, Castedal M, Friman S, Schrumpf E, Foss A, Isoniemi H, Nordin A, Holte K, Rasmussen A, Bergquist A, Vatn MH, Boberg KM (2013)
    Immunosuppression after liver transplantation for primary sclerosing cholangitis influences activity of inflammatory bowel disease
    Clin Gastroenterol Hepatol, 11 (5), 517-23
    DOI 10.1016/j.cgh.2012.12.027, PubMed 23333218
  10. Karlsen TH, Boberg KM (2013)
    Update on primary sclerosing cholangitis
    J Hepatol, 59 (3), 571-82
    DOI 10.1016/j.jhep.2013.03.015, PubMed 23603668
  11. Karlsen TH, Vesterhus M, Boberg KM (2013)
    Review article: controversies in the management of primary biliary cirrhosis and primary sclerosing cholangitis
    Aliment Pharmacol Ther, 39 (3), 282-301
    DOI 10.1111/apt.12581, PubMed 24372568
  12. Kummen M, Schrumpf E, Boberg KM (2013)
    Liver abnormalities in bowel diseases
    Best Pract Res Clin Gastroenterol, 27 (4), 531-42
    DOI 10.1016/j.bpg.2013.06.013, PubMed 24090940
  13. Lindström L, Hultcrantz R, Boberg KM, Friis-Liby I, Bergquist A (2013)
    Association between reduced levels of alkaline phosphatase and survival times of patients with primary sclerosing cholangitis
    Clin Gastroenterol Hepatol, 11 (7), 841-6
    DOI 10.1016/j.cgh.2012.12.032, PubMed 23353641
  14. Liu JZ, Hov JR, Folseraas T, Ellinghaus E, Rushbrook SM, Doncheva NT, Andreassen OA, Weersma RK, Weismüller TJ, Eksteen B, Invernizzi P, Hirschfield GM, Gotthardt DN, Pares A, Ellinghaus D, Shah T, Juran BD, Milkiewicz P, Rust C, Schramm C, Müller T, Srivastava B, Dalekos G, Nöthen MM, Herms S et al. (2013)
    Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
    Nat Genet, 45 (6), 670-5
    DOI 10.1038/ng.2616, PubMed 23603763
  15. Mells GF, Kaser A, Karlsen TH (2013)
    Novel insights into autoimmune liver diseases provided by genome-wide association studies
    J Autoimmun, 46, 41-54
    DOI 10.1016/j.jaut.2013.07.004, PubMed 23931959
  16. Wannhoff A, Hov JR, Folseraas T, Rupp C, Friedrich K, Anmarkrud JA, Weiss KH, Sauer P, Schirmacher P, Boberg KM, Stremmel W, Karlsen TH, Gotthardt DN (2013)
    FUT2 and FUT3 genotype determines CA19-9 cut-off values for detection of cholangiocarcinoma in patients with primary sclerosing cholangitis
    J Hepatol, 59 (6), 1278-84
    DOI 10.1016/j.jhep.2013.08.005, PubMed 23958938

Publications 2012

  1. Andresen K, Boberg KM, Vedeld HM, Honne H, Hektoen M, Wadsworth CA, Clausen OP, Karlsen TH, Foss A, Mathisen O, Schrumpf E, Lothe RA, Lind GE (2012)
    Novel target genes and a valid biomarker panel identified for cholangiocarcinoma
    Epigenetics, 7 (11), 1249-57
    DOI 10.4161/epi.22191, PubMed 22983262
  2. Eskesen AN, Melum E, Moghaddam A, Bjøro K, Verbaan H, Ring-Larsen H, Dalgard O (2012)
    Genetic variants at the ITPA locus protect against ribavirin-induced hemolytic anemia and dose reduction in an HCV G2/G3 cohort
    Eur J Gastroenterol Hepatol, 24 (8), 890-6
    DOI 10.1097/MEG.0b013e3283546efd, PubMed 22584257
  3. Folseraas T, Melum E, Rausch P, Juran BD, Ellinghaus E, Shiryaev A, Laerdahl JK, Ellinghaus D, Schramm C, Weismüller TJ, Gotthardt DN, Hov JR, Clausen OP, Weersma RK, Janse M, Boberg KM, Björnsson E, Marschall HU, Cleynen I, Rosenstiel P, Holm K, Teufel A, Rust C, Gieger C, Wichmann HE et al. (2012)
    Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci
    J Hepatol, 57 (2), 366-75
    DOI 10.1016/j.jhep.2012.03.031, PubMed 22521342
  4. Forster M, Forster P, Elsharawy A, Hemmrich G, Kreck B, Wittig M, Thomsen I, Stade B, Barann M, Ellinghaus D, Petersen BS, May S, Melum E, Schilhabel MB, Keller A, Schreiber S, Rosenstiel P, Franke A (2012)
    From next-generation sequencing alignments to accurate comparison and validation of single-nucleotide variants: the pibase software
    Nucleic Acids Res, 41 (1), e16
    DOI 10.1093/nar/gks836, PubMed 22965131
  5. Fosby B, Karlsen TH, Melum E (2012)
    Recurrence and rejection in liver transplantation for primary sclerosing cholangitis
    World J Gastroenterol, 18 (1), 1-15
    DOI 10.3748/wjg.v18.i1.1, PubMed 22228965
  6. Haugaa H, Thorgersen EB, Pharo A, Boberg KM, Foss A, Line PD, Sanengen T, Almaas R, Grindheim G, Waelgaard L, Pischke SE, Mollnes TE, Inge Tønnessen T (2012)
    Inflammatory markers sampled by microdialysis catheters distinguish rejection from ischemia in liver grafts
    Liver Transpl, 18 (12), 1421-9
    DOI 10.1002/lt.23503, PubMed 22767413
  7. Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN, Andersen V et al. (2012)
    Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
    Nature, 491 (7422), 119-24
    DOI 10.1038/nature11582, PubMed 23128233
  8. Jørgensen KK, Lindström L, Cvancarova M, Castedal M, Friman S, Schrumpf E, Foss A, Isoniemi H, Nordin A, Holte K, Rasmussen A, Bergquist A, Vatn MH, Boberg KM (2012)
    Colorectal neoplasia in patients with primary sclerosing cholangitis undergoing liver transplantation: a Nordic multicenter study
    Scand J Gastroenterol, 47 (8-9), 1021-9
    DOI 10.3109/00365521.2012.685754, PubMed 22577871
  9. Karlsen TH (2012)
    A lecture on the genetics of primary sclerosing cholangitis
    Dig Dis, 30 Suppl 1, 32-8
    DOI 10.1159/000341122, PubMed 23075866
  10. Lindström L, Boberg KM, Wikman O, Friis-Liby I, Hultcrantz R, Prytz H, Sandberg-Gertzén H, Sangfelt P, Rydning A, Folvik G, Gangsøy-Kristiansen M, Danielsson A, Bergquist A (2012)
    High dose ursodeoxycholic acid in primary sclerosing cholangitis does not prevent colorectal neoplasia
    Aliment Pharmacol Ther, 35 (4), 451-7
    DOI 10.1111/j.1365-2036.2011.04966.x, PubMed 22221173
  11. Metzger J, Negm AA, Plentz RR, Weismüller TJ, Wedemeyer J, Karlsen TH, Dakna M, Mullen W, Mischak H, Manns MP, Lankisch TO (2012)
    Urine proteomic analysis differentiates cholangiocarcinoma from primary sclerosing cholangitis and other benign biliary disorders
    Gut, 62 (1), 122-30
    DOI 10.1136/gutjnl-2012-302047, PubMed 22580416
  12. Munk S, Dalsgaard J, Bjerggaard K, Andersen I, Hansen TB, Kehlet H (2012)
    Early recovery after fast-track Oxford unicompartmental knee arthroplasty. 35 patients with minimal invasive surgery
    Acta Orthop, 83 (1), 41-5
    DOI 10.3109/17453674.2012.657578, PubMed 22313368
  13. Næss S, Shiryaev A, Hov JR, Franke A, Karlsen TH (2012)
    Genetics in primary sclerosing cholangitis
    Clin Res Hepatol Gastroenterol, 36 (4), 325-33
    DOI 10.1016/j.clinre.2012.02.003, PubMed 22554879
  14. Srivastava B, Mells GF, Cordell HJ, Muriithi A, Brown M, Ellinghaus E, Franke A, UK-PSC Consortium, Karlsen TH, Sandford RN, Alexander GJ, Chapman RW, Rushbrook SM, Melum E (2012)
    Fine mapping and replication of genetic risk loci in primary sclerosing cholangitis
    Scand J Gastroenterol, 47 (7), 820-6
    DOI 10.3109/00365521.2012.682090, PubMed 22554193

Publications 2011

  1. Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, Lee JC, Goyette P, Imielinski M, Latiano A, Lagacé C, Scott R, Amininejad L, Bumpstead S, Baidoo L, Baldassano RN, Barclay M, Bayless TM, Brand S, Büning C, Colombel JF, Denson LA, De Vos M, Dubinsky M, Edwards C et al. (2011)
    Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
    Nat Genet, 43 (3), 246-52
    DOI 10.1038/ng.764, PubMed 21297633
  2. Boberg KM, Lind GE (2011)
    Primary sclerosing cholangitis and malignancy
    Best Pract Res Clin Gastroenterol, 25 (6), 753-64
    DOI 10.1016/j.bpg.2011.10.002, PubMed 22117640
  3. Folseraas T, Karlsen TH (2011)
    To MMP or not to MMP: a role for matrix metalloproteinase 3 in primary sclerosing cholangitis?
    Liver Int, 31 (6), 751-4
    DOI 10.1111/j.1478-3231.2011.02471.x, PubMed 21645205
  4. Folseraas T, Melum E, Franke A, Karlsen TH (2011)
    Genetics in primary sclerosing cholangitis
    Best Pract Res Clin Gastroenterol, 25 (6), 713-26
    DOI 10.1016/j.bpg.2011.09.010, PubMed 22117637
  5. Holm A, Wu W, Lund-Johansen F (2011)
    Antibody array analysis of labelled proteomes: how should we control specificity?
    N Biotechnol, 29 (5), 578-85
    DOI 10.1016/j.nbt.2011.07.008, PubMed 21840428
  6. Hov JR, Keitel V, Schrumpf E, Häussinger D, Karlsen TH (2011)
    TGR5 sequence variation in primary sclerosing cholangitis
    Dig Dis, 29 (1), 78-84
    DOI 10.1159/000324138, PubMed 21691110
  7. Hov JR, Kosmoliaptsis V, Traherne JA, Olsson M, Boberg KM, Bergquist A, Schrumpf E, Bradley JA, Taylor CJ, Lie BA, Trowsdale J, Karlsen TH (2011)
    Electrostatic modifications of the human leukocyte antigen-DR P9 peptide-binding pocket and susceptibility to primary sclerosing cholangitis
    Hepatology, 53 (6), 1967-76
    DOI 10.1002/hep.24299, PubMed 21413052
  8. Janse M, Lamberts LE, Franke L, Raychaudhuri S, Ellinghaus E, Muri Boberg K, Melum E, Folseraas T, Schrumpf E, Bergquist A, Björnsson E, Fu J, Jan Westra H, Groen HJ, Fehrmann RS, Smolonska J, van den Berg LH, Ophoff RA, Porte RJ, Weismüller TJ, Wedemeyer J, Schramm C, Sterneck M, Günther R, Braun F et al. (2011)
    Three ulcerative colitis susceptibility loci are associated with primary sclerosing cholangitis and indicate a role for IL2, REL, and CARD9
    Hepatology, 53 (6), 1977-85
    DOI 10.1002/hep.24307, PubMed 21425313
  9. Jørgensen KK, Grzyb K, Lundin KE, Clausen OP, Aamodt G, Schrumpf E, Vatn MH, Boberg KM (2011)
    Inflammatory bowel disease in patients with primary sclerosing cholangitis: clinical characterization in liver transplanted and nontransplanted patients
    Inflamm Bowel Dis, 18 (3), 536-45
    DOI 10.1002/ibd.21699, PubMed 21456044
  10. Karlsen TH, Kaser A (2011)
    Deciphering the genetic predisposition to primary sclerosing cholangitis
    Semin Liver Dis, 31 (2), 188-207
    DOI 10.1055/s-0031-1276647, PubMed 21538284
  11. Karlsen TH, Lazaridis KN (2011)
    At the end of the beginning. Foreword
    Semin Liver Dis, 31 (2), 111-3
    DOI 10.1055/s-0031-1276640, PubMed 21538278
  12. Moghaddam A, Melum E, Reinton N, Ring-Larsen H, Verbaan H, Bjøro K, Dalgard O (2011)
    IL28B genetic variation and treatment response in patients with hepatitis C virus genotype 3 infection
    Hepatology, 53 (3), 746-54
    DOI 10.1002/hep.24154, PubMed 21374656
  13. Naalsund A, Lund MB, Mynarek G, Aakhus S, Boberg KM, Nordøy I (2011)
    [A man in his 60s with severe respiratory failure]
    Tidsskr Nor Laegeforen, 131 (17), 1654-7
    DOI 10.4045/tidsskr.11.0110, PubMed 21901039
  14. Wiencke K, Boberg KM (2011)
    Current consensus on the management of primary sclerosing cholangitis
    Clin Res Hepatol Gastroenterol, 35 (12), 786-91
    DOI 10.1016/j.clinre.2011.04.007, PubMed 21963085

Publications 2010

  1. Boberg KM, Chapman RW, Hirschfield GM, Lohse AW, Manns MP, Schrumpf E, International Autoimmune Hepatitis Group (2010)
    Overlap syndromes: the International Autoimmune Hepatitis Group (IAIHG) position statement on a controversial issue
    J Hepatol, 54 (2), 374-85
    DOI 10.1016/j.jhep.2010.09.002, PubMed 21067838
  2. Bowlus CL, Li CS, Karlsen TH, Lie BA, Selmi C (2010)
    Primary sclerosing cholangitis in genetically diverse populations listed for liver transplantation: unique clinical and human leukocyte antigen associations
    Liver Transpl, 16 (11), 1324-30
    DOI 10.1002/lt.22161, PubMed 21031548
  3. Chapman R, Fevery J, Kalloo A, Nagorney DM, Boberg KM, Shneider B, Gores GJ, American Association for the Study of Liver Diseases (2010)
    Diagnosis and management of primary sclerosing cholangitis
    Hepatology, 51 (2), 660-78
    DOI 10.1002/hep.23294, PubMed 20101749
  4. Dolgos S, Hartmann A, Isaksen GA, Simonsen S, Bjørtuft Ø, Boberg KM, Bollerslev J (2010)
    Osteoporosis is a prevalent finding in patients with solid organ failure awaiting transplantation - a population based study
    Clin Transplant, 24 (5), E145-52
    DOI 10.1111/j.1399-0012.2010.01231.x, PubMed 20236290
  5. Ellinghaus E, Ellinghaus D, Stuart PE, Nair RP, Debrus S, Raelson JV, Belouchi M, Fournier H, Reinhard C, Ding J, Li Y, Tejasvi T, Gudjonsson J, Stoll SW, Voorhees JJ, Lambert S, Weidinger S, Eberlein B, Kunz M, Rahman P, Gladman DD, Gieger C, Wichmann HE, Karlsen TH, Mayr G et al. (2010)
    Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2
    Nat Genet, 42 (11), 991-5
    DOI 10.1038/ng.689, PubMed 20953188
  6. Franke A, Balschun T, Sina C, Ellinghaus D, Häsler R, Mayr G, Albrecht M, Wittig M, Buchert E, Nikolaus S, Gieger C, Wichmann HE, Sventoraityte J, Kupcinskas L, Onnie CM, Gazouli M, Anagnou NP, Strachan D, McArdle WL, Mathew CG, Rutgeerts P, Vermeire S, Vatn MH, IBSEN study group, Krawczak M et al. (2010)
    Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL)
    Nat Genet, 42 (4), 292-4
    DOI 10.1038/ng.553, PubMed 20228798
  7. Friman S, Foss A, Isoniemi H, Olausson M, Höckerstedt K, Yamamoto S, Karlsen TH, Rizell M, Ericzon BG (2010)
    Liver transplantation for cholangiocarcinoma: selection is essential for acceptable results
    Scand J Gastroenterol, 46 (3), 370-5
    DOI 10.3109/00365521.2010.533384, PubMed 21073376
  8. Hollenbach JA, Meenagh A, Sleator C, Alaez C, Bengoche M, Canossi A, Contreras G, Creary L, Evseeva I, Gorodezky C, Hardie RA, Karlsen TH, Lie B, Luo M, Martinetti M, Navarette C, de Oliveira DC, Ozzella G, Pasi A, Pavlova E, Pinto S, Porto LC, Santos P, Slavcev A, Srinak D et al. (2010)
    Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA
    Tissue Antigens, 76 (1), 9-17
    DOI 10.1111/j.1399-0039.2010.01459.x, PubMed 20331834
  9. Holm K, Melum E, Franke A, Karlsen TH (2010)
    SNPexp - A web tool for calculating and visualizing correlation between HapMap genotypes and gene expression levels
    BMC Bioinformatics, 11, 600
    DOI 10.1186/1471-2105-11-600, PubMed 21167019
  10. Hov JR, Keitel V, Laerdahl JK, Spomer L, Ellinghaus E, ElSharawy A, Melum E, Boberg KM, Manke T, Balschun T, Schramm C, Bergquist A, Weismüller T, Gotthardt D, Rust C, Henckaerts L, Onnie CM, Weersma RK, Sterneck M, Teufel A, Runz H, Stiehl A, Ponsioen CY, Wijmenga C, Vatn MH et al. (2010)
    Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis
    PLoS One, 5 (8), e12403
    DOI 10.1371/journal.pone.0012403, PubMed 20811628
  11. Hov JR, Lleo A, Selmi C, Woldseth B, Fabris L, Strazzabosco M, Karlsen TH, Invernizzi P (2010)
    Genetic associations in Italian primary sclerosing cholangitis: heterogeneity across Europe defines a critical role for HLA-C
    J Hepatol, 52 (5), 712-7
    DOI 10.1016/j.jhep.2009.11.029, PubMed 20347497
  12. Karlsen TH, Hov JR (2010)
    Genetics of cholestatic liver disease in 2010
    Curr Opin Gastroenterol, 26 (3), 251-8
    DOI 10.1097/MOG.0b013e328336807d, PubMed 20042859
  13. Karlsen TH, Melum E, Franke A (2010)
    The utility of genome-wide association studies in hepatology
    Hepatology, 51 (5), 1833-42
    DOI 10.1002/hep.23564, PubMed 20232293
  14. Karlsen TH, Schrumpf E, Boberg KM (2010)
    Primary sclerosing cholangitis
    Best Pract Res Clin Gastroenterol, 24 (5), 655-66
    DOI 10.1016/j.bpg.2010.07.005, PubMed 20955968
  15. Karlsen TH, Schrumpf E, Boberg KM (2010)
    Update on primary sclerosing cholangitis
    Dig Liver Dis, 42 (6), 390-400
    DOI 10.1016/j.dld.2010.01.011, PubMed 20172772
  16. Lorentzen AR, Melum E, Ellinghaus E, Smestad C, Mero IL, Aarseth JH, Myhr KM, Celius EG, Lie BA, Karlsen TH, Franke A, Harbo HF (2010)
    Association to the Glypican-5 gene in multiple sclerosis
    J Neuroimmunol, 226 (1-2), 194-7
    DOI 10.1016/j.jneuroim.2010.07.003, PubMed 20692050
  17. Melum E, Franke A, Schramm C, Weismüller TJ, Gotthardt DN, Offner FA, Juran BD, Laerdahl JK, Labi V, Björnsson E, Weersma RK, Henckaerts L, Teufel A, Rust C, Ellinghaus E, Balschun T, Boberg KM, Ellinghaus D, Bergquist A, Sauer P, Ryu E, Hov JR, Wedemeyer J, Lindkvist B, Wittig M et al. (2010)
    Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci
    Nat Genet, 43 (1), 17-9
    DOI 10.1038/ng.728, PubMed 21151127
  18. Melum E, May S, Schilhabel MB, Thomsen I, Karlsen TH, Rosenstiel P, Schreiber S, Franke A (2010)
    SNP discovery performance of two second-generation sequencing platforms in the NOD2 gene region
    Hum Mutat, 31 (7), 875-85
    DOI 10.1002/humu.21276, PubMed 20506538
  19. Ponsioen CY, Reitsma JB, Boberg KM, Aabakken L, Rauws EA, Schrumpf E (2010)
    Validation of a cholangiographic prognostic model in primary sclerosing cholangitis
    Endoscopy, 42 (9), 742-7
    DOI 10.1055/s-0030-1255527, PubMed 20623444

Publications 2009

  1. Forsbring M, Vik ES, Dalhus B, Karlsen TH, Bergquist A, Schrumpf E, Bjørås M, Boberg KM, Alseth I (2009)
    Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma
    Carcinogenesis, 30 (7), 1147-54
    DOI 10.1093/carcin/bgp118, PubMed 19443904
  2. Karlsen TH (2009)
    Genome-wide association studies reach hepatology
    J Hepatol, 50 (6), 1278-80
    DOI 10.1016/j.jhep.2009.03.002, PubMed 19395112
  3. Karlsen TH, Franke A, Melum E, Kaser A, Hov JR, Balschun T, Lie BA, Bergquist A, Schramm C, Weismüller TJ, Gotthardt D, Rust C, Philipp EE, Fritz T, Henckaerts L, Weersma RK, Stokkers P, Ponsioen CY, Wijmenga C, Sterneck M, Nothnagel M, Hampe J, Teufel A, Runz H, Rosenstiel P et al. (2009)
    Genome-wide association analysis in primary sclerosing cholangitis
    Gastroenterology, 138 (3), 1102-11
    DOI 10.1053/j.gastro.2009.11.046, PubMed 19944697
  4. Lorentzen AR, Karlsen TH, Olsson M, Smestad C, Mero IL, Woldseth B, Sun JY, Senitzer D, Celius EG, Thorsby E, Spurkland A, Lie BA, Harbo HF (2009)
    Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis
    Ann Neurol, 65 (6), 658-66
    DOI 10.1002/ana.21695, PubMed 19630074
  5. Melum E, Franke A, Karlsen TH (2009)
    Genome-wide association studies--a summary for the clinical gastroenterologist
    World J Gastroenterol, 15 (43), 5377-96
    DOI 10.3748/wjg.15.5377, PubMed 19916168
  6. Michalsen S, Schrumpf E, Beiske K, Tierens A, Stenberg V, Tjønnfjord GE (2009)
    [Large granular lymphocytic leukaemia]
    Tidsskr Nor Laegeforen, 129 (11), 1098-102
    DOI 10.4045/tidsskr.09.0152, PubMed 19488091
  7. Scholz T, Karlsen TH, Sanengen T, Schrumpf E, Line PD, Boberg KM, Jörgensen PF, Fosby B, Bentdal O, Ostensen AB, Osnes S, Riddervold F, Haugaa H, Hausken J, Bergmann JB, Foss S, Björo K, Foss A, Levertransplantasjonsgruppen ved Oslo universitetssykehus, Rikshospitalet (2009)
    [Liver transplantation in Norway through 25 years]
    Tidsskr Nor Laegeforen, 129 (24), 2587-92
    DOI 10.4045/tidsskr.09.1106, PubMed 20029553
  8. Yu X, Wieczorek S, Franke A, Yin H, Pierer M, Sina C, Karlsen TH, Boberg KM, Bergquist A, Kunz M, Witte T, Gross WL, Epplen JT, Alarcón-Riquelme ME, Schreiber S, Ibrahim SM (2009)
    Association of UCP2 -866 G/A polymorphism with chronic inflammatory diseases
    Genes Immun, 10 (6), 601-5
    DOI 10.1038/gene.2009.29, PubMed 19387457

Publications 2008

  1. Björnsson E, Olsson R, Bergquist A, Lindgren S, Braden B, Chapman RW, Boberg KM, Angulo P (2008)
    The natural history of small-duct primary sclerosing cholangitis
    Gastroenterology, 134 (4), 975-80
    DOI 10.1053/j.gastro.2008.01.042, PubMed 18395078
  2. Franke A, Balschun T, Karlsen TH, Hedderich J, May S, Lu T, Schuldt D, Nikolaus S, Rosenstiel P, Krawczak M, Schreiber S (2008)
    Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis
    Nat Genet, 40 (6), 713-5
    DOI 10.1038/ng.148, PubMed 18438405
  3. Franke A, Balschun T, Karlsen TH, Sventoraityte J, Nikolaus S, Mayr G, Domingues FS, Albrecht M, Nothnagel M, Ellinghaus D, Sina C, Onnie CM, Weersma RK, Stokkers PC, Wijmenga C, Gazouli M, Strachan D, McArdle WL, Vermeire S, Rutgeerts P, Rosenstiel P, Krawczak M, Vatn MH, IBSEN study group, Mathew CG et al. (2008)
    Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
    Nat Genet, 40 (11), 1319-23
    DOI 10.1038/ng.221, PubMed 18836448
  4. Hennes EM, Zeniya M, Czaja AJ, Parés A, Dalekos GN, Krawitt EL, Bittencourt PL, Porta G, Boberg KM, Hofer H, Bianchi FB, Shibata M, Schramm C, Eisenmann de Torres B, Galle PR, McFarlane I, Dienes HP, Lohse AW, International Autoimmune Hepatitis Group (2008)
    Simplified criteria for the diagnosis of autoimmune hepatitis
    Hepatology, 48 (1), 169-76
    DOI 10.1002/hep.22322, PubMed 18537184
  5. Hov JR, Boberg KM, Karlsen TH (2008)
    Autoantibodies in primary sclerosing cholangitis
    World J Gastroenterol, 14 (24), 3781-91
    DOI 10.3748/wjg.14.3781, PubMed 18609700
  6. Karlsen TH, Schrumpf E, Boberg KM (2008)
    Gallbladder polyps in primary sclerosing cholangitis: not so benign
    Curr Opin Gastroenterol, 24 (3), 395-9
    DOI 10.1097/MOG.0b013e3282f5727a, PubMed 18408471
  7. Melum E, Buch S, Schafmayer C, Kalthoff H, Tepel J, Schreiber S, Karlsen TH, Hampe J (2008)
    Investigation of cholangiocarcinoma associated NKG2D polymorphisms in colorectal carcinoma
    Int J Cancer, 123 (1), 241-2
    DOI 10.1002/ijc.23517, PubMed 18398827
  8. Melum E, Karlsen TH, Bergquist A, Schrumpf E, Boberg KM (2008)
    An interleukin-6 (IL-6) receptor polymorphism affecting serum levels of IL-6 does not increase the risk of cholangiocarcinoma in primary sclerosing cholangitis
    Am J Gastroenterol, 103 (4), 1045; author reply 1045-6
    DOI 10.1111/j.1572-0241.2007.01772_5.x, PubMed 18397431
  9. Melum E, Karlsen TH, Schrumpf E, Bergquist A, Thorsby E, Boberg KM, Lie BA (2008)
    Cholangiocarcinoma in primary sclerosing cholangitis is associated with NKG2D polymorphisms
    Hepatology, 47 (1), 90-6
    DOI 10.1002/hep.21964, PubMed 18023027

 
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