Publicatons

Publications published since 2008 from OUS - Norwegian PSC Research Center

404 publications found

Publications 2025

1. Molinaro A, Engesæter LK, Jorns C, Nordin A, Rasmussen A, Line PD, Pall V, Ericzon BG, Bennet W, Hov JR, Melum E (2025)
   Outcome of Liver Retransplantation in Patients With Primary Sclerosing Cholangitis
   Liver Int, 45 (1), e16214
   DOI 10.1111/liv.16214, PubMed 39679639

Publications 2024

1. Bratseth V, Nendl A, Raju SC, Holm K, Broch K, Hov JR, Seljeflot I, Trøseid M, Awoyemi A (2024)
   Gut dysbiosis and neutrophil extracellular traps in chronic heart failure
   Int J Cardiol, 419, 132689
   DOI 10.1016/j.ijcard.2024.132689, PubMed 39489348
2. Burra P, Zanetto A, Schnabl B, Reiberger T, Montano-Loza AJ, Asselta R, Karlsen TH, Tacke F (2024)
   Hepatic immune regulation and sex disparities
   Nat Rev Gastroenterol Hepatol, 21 (12), 869-884
   DOI 10.1038/s41575-024-00974-5, PubMed 39237606
3. Burra P, Zanetto A, Schnabl B, Reiberger T, Montano-Loza AJ, Asselta R, Karlsen TH, Tacke F (2024)
   Author Correction: Hepatic immune regulation and sex disparities
   Nat Rev Gastroenterol Hepatol, 21 (12), 887
   DOI 10.1038/s41575-024-01007-x, PubMed 39390290
4. Frank AK, Chung BK, De Novales MLL, Engesæter LK, Hoyle HW, Øgaard J, Heslop J, Karlsen TH, Tysoe O, Brevini T, Tchorz JS, Vallier L, Mohorianu I, Sampaziotis F, Melum E (2024)
   Single-Cell Transcriptomic Profiling of Cholangiocyte Organoids Derived from Bile Ducts of Primary Sclerosing Cholangitis Patients
   Dig Dis Sci, 69 (10), 3810-3823
   DOI 10.1007/s10620-024-08570-y, PubMed 39160386
5. Gregersen I, Kong XY, Kooijman S, Foyn H, Grannes H, Olsen MB, Lone AM, Yang K, Quiles-Jiménez A, Tran M, Øgaard J, Segers FM, Rashidi A, Sagen EL, Lauritzen KH, Pronk ACM, de Boer JF, Holven KB, Melum E, Aukrust P, Taskén K, Holm S, Rensen PCN, Dahl TB, Halvorsen B (2024)
   T cells with increased responsiveness cause obesity in mice without diet intervention
   iScience, 27 (4), 109471
   DOI 10.1016/j.isci.2024.109471, PubMed 38551005
6. Grimsrud MM, Forster M, Goeppert B, Hemmrich-Stanisak G, Sax I, Grzyb K, Braadland PR, Charbel A, Metzger C, Albrecht T, Steiert TA, Schlesner M, Manns MP, Vogel A, Yaqub S, Karlsen TH, Schirmacher P, Boberg KM, Franke A, Roessler S, Folseraas T (2024)
   Whole-exome sequencing reveals novel cancer genes and actionable targets in biliary tract cancers in primary sclerosing cholangitis
   Hepatol Commun, 8 (7)
   DOI 10.1097/HC9.0000000000000461, PubMed 38967597
7. He MM, Wang K, Lo CH, Zhang Y, Polychronidis G, Knudsen MD, Zhong R, Ma Y, Wu K, Chan AT, Giovannucci EL, Ogino S, Ng K, Meyerhardt JA, Song M (2024)
   Post-diagnostic multivitamin supplement use and colorectal cancer survival: A prospective cohort study
   Cancer, 130 (12), 2169-2179
   DOI 10.1002/cncr.35234, PubMed 38319287
8. Hov JR (2024)
   Sclerosing cholangitis and inflammatory bowel disease: a paradoxical relationship?
   Gut, 74 (1), 1-2
   DOI 10.1136/gutjnl-2024-332835, PubMed 39025493
9. Hov JR, Molberg Ø, Karlsen TH (2024)
   Tubulin beta 5 is not the target of antineutrophil antibodies in primary sclerosing cholangitis
   Clin Exp Immunol, 218 (1), 75-77
   DOI 10.1093/cei/uxae053, PubMed 38960384
10. Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, Pyzik M, Ostrowski MA, Glickman JN, Rudd CE, Ploegh HL, Franke A, Petsko GA, Kuchroo VK, Blumberg RS (2024)
    Author Correction: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion
    Nature, 626 (8001), E19
    DOI 10.1038/s41586-024-07164-y, PubMed 38336833
11. Hussain N, Ma C, Hirschfield G, Walmsley M, Hanford P, Vesterhus M, Kowdley K, Bergquist A, Ponsioen C, Levy C, Assis D, Schramm C, Bowlus C, Trauner M, Aiyegbusi OL, Jairath V, Trivedi PJ (2024)
    Protocol for the development of a core outcome set for clinical trials in primary sclerosing cholangitis
    BMJ Open, 14 (6), e080143
    DOI 10.1136/bmjopen-2023-080143, PubMed 38926149
12. Jaeger JW, Brandt A, Gui W, Yergaliyev T, Hernández-Arriaga A, Muthu MM, Edlund K, Elashy A, Molinaro A, Möckel D, Sarges J, Halibasic E, Trauner M, Kahles F, Rolle-Kampczyk U, Hengstler J, Schneider CV, Lammers T, Marschall HU, von Bergen M, Camarinha-Silva A, Bergheim I, Trautwein C, Schneider KM (2024)
    Microbiota modulation by dietary oat beta-glucan prevents steatotic liver disease progression
    JHEP Rep, 6 (3), 100987
    DOI 10.1016/j.jhepr.2023.100987, PubMed 38328439
13. Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B (2024)
    Retraction Note: Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
    Sci Rep, 14 (1), 3704
    DOI 10.1038/s41598-024-54117-6, PubMed 38355714
14. Karlsen TH, Kaasen Jørgensen K, Bergquist A (2024)
    Medical treatment of primary sclerosing cholangitis: What have we learned and where are we going?
    Hepatology (in press)
    DOI 10.1097/HEP.0000000000001172, PubMed 39585345
15. Karlsen TH, Rutter H, Carrieri P, Zelber-Sagi S, Engebretsen E, Hutchinson S, Voigt K, Guha N, Berzigotti A, Schomerus G, Gines P, Buti M, Burra P, Manns MP, Krag A, Kleinert S (2024)
    The EASL-Lancet Commission on liver health in Europe: prevention, case-finding, and early diagnosis to reduce liver-related mortality
    Lancet, 403 (10436), 1522-1524
    DOI 10.1016/S0140-6736(24)00204-6, PubMed 38359860
16. Lin W, Gerullat L, Braadland PR, Fournier A, Hov JR, Globisch D (2024)
    Rapid and Bifunctional Chemoselective Metabolome Analysis of Liver Disease Plasma Using the Reagent 4-Nitrophenyl-2H-azirine
    Angew Chem Int Ed Engl, 63 (14), e202318579
    DOI 10.1002/anie.202318579, PubMed 38235602
17. Molinaro A, Wauters L (2024)
    Young GI angle: UEG research fellowship-Benefits of going abroad
    United European Gastroenterol J, 12 (7), 984-985
    DOI 10.1002/ueg2.12654, PubMed 39207814
18. Nikitina D, Lukosevicius R, Tilinde D, Muskieta T, Hov JR, Melum E, Klovins J, Org E, Kiudelis G, Kupcinskas J, Skieceviciene J (2024)
    Cell-Free Microbial DNA Analysis: Effects of Blood Plasma and Serum Quantity, Biobanking Protocols, and Isolation Kits
    Biopreserv Biobank, 22 (4), 363-372
    DOI 10.1089/bio.2023.0048, PubMed 38416864
19. Oldereid TS, Jiang X, Øgaard J, Schrumpf E, Bjørnholt JV, Rasmussen H, Melum E (2024)
    Microbial exposure during early life regulates development of bile duct inflammation
    Scand J Gastroenterol, 59 (2), 192-201
    DOI 10.1080/00365521.2023.2278423, PubMed 37997753
20. Poch T, Bahn J, Casar C, Krause J, Evangelakos I, Gilladi H, Kunzmann LK, Laschtowitz A, Iuso N, Schäfer AM, Liebig LA, Steinmann S, Sebode M, Folseraas T, Engesæter LK, Karlsen TH, Franke A, Hubner N, Schlein C, Galun E, Huber S, Lohse AW, Gagliani N, Schwinge D, Schramm C (2024)
    Intergenic risk variant rs56258221 skews the fate of naive CD4⁺ T cells via miR4464-BACH2 interplay in primary sclerosing cholangitis
    Cell Rep Med, 5 (7), 101620
    DOI 10.1016/j.xcrm.2024.101620, PubMed 38901430
21. Raju SC, Molinaro A, Awoyemi A, Jørgensen SF, Braadland PR, Nendl A, Seljeflot I, Ueland PM, McCann A, Aukrust P, Vestad B, Mayerhofer C, Broch K, Gullestad L, Lappegård KT, Halvorsen B, Kristiansen K, Hov JR, Trøseid M (2024)
    Microbial-derived imidazole propionate links the heart failure-associated microbiome alterations to disease severity
    Genome Med, 16 (1), 27
    DOI 10.1186/s13073-024-01296-6, PubMed 38331891
22. Serrano-Villar S, Tincati C, Raju SC, Sáenz JS, Moreno E, Bargiela R, Cabello-Ubeda A, Sendagorta E, Kurz A, Perez Molina JA, de Benito A, Hov JR, Fernandez-Lopez L, Muriel A, Del Campo R, Moreno S, Trøseid M, Seifert J, Ferrer M (2024)
    Author Correction: Microbiome-derived cobalamin and succinyl-CoA as biomarkers for improved screening of anal cancer
    Nat Med, 30 (1), 303
    DOI 10.1038/s41591-023-02529-8, PubMed 37587221
23. Staff AC, Fjeldstad HE, Olsen MB, Øgaard J, Viken MK, Kramer CSM, Eikmans M, Kroneis T, Sallinger K, Kanaan SB, Sugulle M, Jacobsen DP (2024)
    Foetal Microchimerism Correlates With Foetal-Maternal Histocompatibility Both During Pregnancy and Postpartum
    HLA, 104 (4), e15717
    DOI 10.1111/tan.15717, PubMed 39435899
24. Trøseid M, Molinaro A, Gelpi M, Vestad B, Kofoed KF, Fuchs A, Køber L, Holm K, Benfield T, Ueland PM, Hov JR, Nielsen SD, Knudsen AD (2024)
    Gut Microbiota Alterations and Circulating Imidazole Propionate Levels Are Associated With Obstructive Coronary Artery Disease in People With HIV
    J Infect Dis, 229 (3), 898-907
    DOI 10.1093/infdis/jiad604, PubMed 38195204
25. Ullern A, Holm K, Røssevold AH, Andresen NK, Bang C, Lingjærde OC, Naume B, Hov JR, Kyte JA (2024)
    Gut microbiota diversity is prognostic and associated with benefit from chemo-immunotherapy in metastatic triple-negative breast cancer
    Mol Oncol (in press)
    DOI 10.1002/1878-0261.13760, PubMed 39545921
26. van Keulen AM, Buettner S, Olthof PB, Klümpen HJ, Erdmann JI, Izquierdo-Sanchez L, Banales JM, Goeppert B, Roessler S, Zieniewicz K, Lamarca A, Valle JW, La Casta A, Hoogwater FJH, Donadon M, Scheiter A, Marzioni M, Adeva J, Kiudeliene E, Fernández JMU, Vidili G, Mocan T, Fabris L, Krawczyk M, Folseraas T et al. (2024)
    Comparing Survival of Perihilar Cholangiocarcinoma After R1 Resection Versus Palliative Chemotherapy for Unresected Localized Disease
    Ann Surg Oncol, 31 (10), 6495-6503
    DOI 10.1245/s10434-024-15582-5, PubMed 38896226
27. Yang M, Kaarbø M, Myhre V, Reims HM, Karlsen TH, Wang J, Rognes T, Halvorsen B, Fevang B, Lundin KEA, Aukrust P, Bjørås M, Jørgensen SF (2024)
    Altered Genome-Wide DNA Methylation in the Duodenum of Common Variable Immunodeficiency Patients
    J Clin Immunol, 44 (6), 133
    DOI 10.1007/s10875-024-01726-5, PubMed 38780872

Publications 2023

1. Al Khatib I, Deng J, Lei Y, Torres-Odio S, Rojas GR, Newman LE, Chung BK, Symes A, Zhang H, Huang SN, Pommier Y, Khan A, Shadel GS, West AP, Gibson WT, Shutt TE (2023)
   Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT
   Hum Mol Genet, 32 (15), 2422-2440
   DOI 10.1093/hmg/ddad062, PubMed 37129502
2. Andersen IM, Reims HM, Grzyb K, Fevang B, Melum E, Aukrust P, Wiencke K, Nordøy I, Line PD, Jørgensen SF (2023)
   Long-term survival after liver transplantation in patients with common variable immunodeficiency
   Liver Transpl, 29 (8), 894-899
   DOI 10.1097/LVT.0000000000000130, PubMed 36932715
3. Bergsmark T, Engesæter LK, Rasmussen A, Bennet W, Nordin A, Pall V, Line PD, Ericzon BG, Melum E (2023)
   Long-term survival after liver transplantation for alcohol-related liver disease in the Nordic countries
   Scand J Gastroenterol, 58 (8), 923-930
   DOI 10.1080/00365521.2023.2184193, PubMed 36872559
4. Braadland PR, Bergquist A, Kummen M, Bossen L, Engesæter LK, Reims HM, Björk I, Grzyb K, Abildgaard A, Småstuen MC, Folseraas T, Trøseid M, Ulvik A, Ueland PM, Melum E, Line PD, Høivik ML, Grønbæk H, Karlsen TH, Vesterhus M, Hov JR (2023)
   Clinical and biochemical impact of vitamin B6 deficiency in primary sclerosing cholangitis before and after liver transplantation
   J Hepatol, 79 (4), 955-966
   DOI 10.1016/j.jhep.2023.05.038, PubMed 37328069
5. Busek M, Aizenshtadt A, Koch T, Frank A, Delon L, Martinez MA, Golovin A, Dumas C, Stokowiec J, Gruenzner S, Melum E, Krauss S (2023)
   Pump-less, recirculating organ-on-a-chip (rOoC) platform
   Lab Chip, 23 (4), 591-608
   DOI 10.1039/d2lc00919f, PubMed 36655405
6. Carbone M, Della Penna A, Mazzarelli C, De Martin E, Villard C, Bergquist A, Line PD, Neuberger JM, Al-Shakhshir S, Trivedi PJ, Baumann U, Cristoferi L, Hov J, Fischler B, Hadzic NH, Debray D, D'Antiga L, Selzner N, Belli LS, Nadalin S (2023)
   Liver Transplantation for Primary Sclerosing Cholangitis (PSC) With or Without Inflammatory Bowel Disease (IBD)-A European Society of Organ Transplantation (ESOT) Consensus Statement
   Transpl Int, 36, 11729
   DOI 10.3389/ti.2023.11729, PubMed 37841645
7. De Muynck K, Heyerick L, De Ponti FF, Vanderborght B, Meese T, Van Campenhout S, Baudonck L, Gijbels E, Rodrigues PM, Banales JM, Vesterhuus M, Folseraas T, Scott CL, Vinken M, Van der Linden M, Hoorens A, Van Dorpe J, Lefere S, Geerts A, Van Nieuwerburgh F, Verhelst X, Van Vlierberghe H, Devisscher L (2023)
   Osteopontin characterizes bile duct-associated macrophages and correlates with liver fibrosis severity in primary sclerosing cholangitis
   Hepatology, 79 (2), 269-288
   DOI 10.1097/HEP.0000000000000557, PubMed 37535809
8. Ecklu-Mensah G, Choo-Kang C, Maseng MG, Donato S, Bovet P, Viswanathan B, Bedu-Addo K, Plange-Rhule J, Oti Boateng P, Forrester TE, Williams M, Lambert EV, Rae D, Sinyanya N, Luke A, Layden BT, O'Keefe S, Gilbert JA, Dugas LR (2023)
   Gut microbiota and fecal short chain fatty acids differ with adiposity and country of origin: the METS-microbiome study
   Nat Commun, 14 (1), 5160
   DOI 10.1038/s41467-023-40874-x, PubMed 37620311
9. Gjersvik P, Falk RS, Roscher I, Rizvi SMH, Mjøen G, Gude E, Leuckfeld I, Boberg KM, Veierød MB, Robsahm TE (2023)
   Rates of Second Tumor, Metastasis, and Death From Cutaneous Squamous Cell Carcinoma in Patients With and Without Transplant-Associated Immunosuppression
   JAMA Dermatol, 159 (9), 923-929
   DOI 10.1001/jamadermatol.2023.2029, PubMed 37466985
10. Grant CW, Juran BD, Ali AH, Schlicht EM, Bianchi JK, Hu X, Liang Y, Jarrell Z, Liu KH, Go YM, Jones DP, Walker DI, Miller GW, Folseraas T, Karlsen TH, LaRusso NF, Gores GJ, Athreya AP, Lazaridis KN (2023)
    Environmental chemicals and endogenous metabolites in bile of USA and Norway patients with primary sclerosing cholangitis
    Exposome, 3 (1), osac011
    DOI 10.1093/exposome/osac011, PubMed 36687160
11. Graupera I, Thiele M, Ma AT, Serra-Burriel M, Pich J, Fabrellas N, Caballeria L, de Knegt RJ, Grgurevic I, Reichert M, Roulot D, Schattenberg JM, Pericas JM, Angeli P, Tsochatzis EA, Guha IN, Garcia-Retortillo M, Morillas RM, Hernández R, Hoyo J, Fuentes M, Madir A, Juanola A, Soria A, Juan M et al. (2023)
    Correction: LiverScreen project: study protocol for screening for liver fibrosis in the general population in European countries
    BMC Public Health, 23 (1), 923
    DOI 10.1186/s12889-023-15867-6, PubMed 37217864
12. Gui W, Hole MJ, Molinaro A, Edlund K, Jørgensen KK, Su H, Begher-Tibbe B, Gaßler N, Schneider CV, Muthukumarasamy U, Mohs A, Liao L, Jaeger J, Mertens CJ, Bergheim I, Strowig T, Hengstler JG, Hov JR, Marschall HU, Trautwein C, Schneider KM (2023)
    Colitis ameliorates cholestatic liver disease via suppression of bile acid synthesis
    Nat Commun, 14 (1), 3304
    DOI 10.1038/s41467-023-38840-8, PubMed 37280200
13. Han Y, Byun J, Zhu C, Sun R, Roh JY, Cordell HJ, Lee HS, Shaw VR, Kang SW, Razjouyan J, Cooley MA, Hassan MM, Siminovitch KA, Folseraas T, Ellinghaus D, Bergquist A, Rushbrook SM, Franke A, Karlsen TH, Lazaridis KN, International PSC Study Group, McGlynn KA, Roberts LR, Amos CI (2023)
    Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis
    Nat Commun, 14 (1), 1069
    DOI 10.1038/s41467-023-36678-8, PubMed 36828809
14. Harrison SP, Siller R, Tanaka Y, Chollet ME, de la Morena-Barrio ME, Xiang Y, Patterson B, Andersen E, Bravo-Pérez C, Kempf H, Åsrud KS, Lunov O, Dejneka A, Mowinckel MC, Stavik B, Sandset PM, Melum E, Baumgarten S, Bonanini F, Kurek D, Mathapati S, Almaas R, Sharma K, Wilson SR, Skottvoll FS et al. (2023)
    Scalable production of tissue-like vascularized liver organoids from human PSCs
    Exp Mol Med, 55 (9), 2005-2024
    DOI 10.1038/s12276-023-01074-1, PubMed 37653039
15. Haukeland JW, Vesterhus MN, Jørgensen KK, Frigstad SO, Karlsen TH (2023)
    [The FIB-4 test as a decision-making tool]
    Tidsskr Nor Laegeforen, 143 (5)
    DOI 10.4045/tidsskr.23.0176, PubMed 36987901
16. Helgadottir H, Folseraas T, Kemmerich G, Aabakken L, Jørgensen KK, Vesterhus M (2023)
    [Primary sclerosing cholangitis]
    Tidsskr Nor Laegeforen, 143 (17)
    DOI 10.4045/tidsskr.23.0156, PubMed 37987062
17. Helgadottir H, Vesterhus M (2023)
    Noninvasive evaluation of fibrosis in adult biliary diseases
    Curr Opin Gastroenterol, 39 (2), 83-88
    DOI 10.1097/MOG.0000000000000909, PubMed 36821455
18. Hole MJ, Jørgensen KK, Holm K, Braadland PR, Meyer-Myklestad MH, Medhus AW, Reikvam DH, Götz A, Grzyb K, Boberg KM, Karlsen TH, Kummen M, Hov JR (2023)
    A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation
    Hepatology, 77 (3), 715-728
    DOI 10.1002/hep.32773, PubMed 36056902
19. Hole MJ, Jørgensen KK, Holm K, Braadland PR, Meyer-Myklestad MH, Medhus AW, Reikvam DH, Götz A, Grzyb K, Boberg KM, Karlsen TH, Kummen M, Hov JR (2023)
    Reply: The mucosal gut signature in primary sclerosing cholangitis before and after liver transplantation. Is the dysbiosis index really predictive for the recurrence of PSC?
    Hepatology, 77 (6), E188-E189
    DOI 10.1097/HEP.0000000000000340, PubMed 36815351
20. Hov JR (2023)
    Editorial: dietary interventions to understand and treat primary sclerosing cholangitis-is gluten-free diet a starting point?
    Aliment Pharmacol Ther, 57 (2), 265-266
    DOI 10.1111/apt.17326, PubMed 36565005
21. Jiang X, Otterdal K, Chung BK, Maucourant C, Rønneberg JD, Zimmer CL, Øgaard J, Boichuk Y, Holm S, Geanon D, Schneditz G, Bergquist A, Björkström NK, Melum E (2023)
    Cholangiocytes Modulate CD100 Expression in the Liver and Facilitate Pathogenic T-Helper 17 Cell Differentiation
    Gastroenterology, 166 (4), 667-679
    DOI 10.1053/j.gastro.2023.11.283, PubMed 37995866
22. Juul FE, Hov JER, Trøseid M, Johnsen PH, Valeur J (2023)
    [Gut microbiota and intestinal disease –a sober warning]
    Tidsskr Nor Laegeforen, 143 (10)
    DOI 10.4045/tidsskr.23.0121, PubMed 37376933
23. Krag A, Buti M, Lazarus JV, Allen AM, Bowman J, Burra P, Donnini G, Duseja A, El-Sayed MH, Gastaldelli A, Hainsworth B, Karlsen TH, Kessler M, Korenjak M, Mark HE, Mann JP, Miller V, Pessoa MG, Piñeiro D, Sarin SK, Singh SP, Rinella ME, Willemse J, Younossi ZM, Francque SM (2023)
    Uniting to defeat steatotic liver disease: A global mission to promote healthy livers and healthy lives
    J Hepatol, 79 (5), 1076-1078
    DOI 10.1016/j.jhep.2023.07.029, PubMed 37634993
24. Lapitz A, Azkargorta M, Milkiewicz P, Olaizola P, Zhuravleva E, Grimsrud MM, Schramm C, Arbelaiz A, O'Rourke CJ, La Casta A, Milkiewicz M, Pastor T, Vesterhus M, Jimenez-Agüero R, Dill MT, Lamarca A, Valle JW, Macias RIR, Izquierdo-Sanchez L, Pérez Castaño Y, Caballero-Camino FJ, Riaño I, Krawczyk M, Ibarra C, Bustamante J et al. (2023)
    Liquid biopsy-based protein biomarkers for risk prediction, early diagnosis, and prognostication of cholangiocarcinoma
    J Hepatol, 79 (1), 93-108
    DOI 10.1016/j.jhep.2023.02.027, PubMed 36868481
25. Macpherson ME, Skarpengland T, Hov JR, Ranheim T, Vestad B, Dahl TB, Fraz MSA, Michelsen AE, Holven KB, Fevang B, Berge RK, Aukrust P, Halvorsen B, Jørgensen SF (2023)
    Increased Plasma Levels of Triglyceride-Enriched Lipoproteins Associate with Systemic Inflammation, Lipopolysaccharides, and Gut Dysbiosis in Common Variable Immunodeficiency
    J Clin Immunol, 43 (6), 1229-1240
    DOI 10.1007/s10875-023-01475-x, PubMed 36995502
26. Mayer C, Nehring S, Kücken M, Repnik U, Seifert S, Sljukic A, Delpierre J, Morales-Navarrete H, Hinz S, Brosch M, Chung B, Karlsen T, Huch M, Kalaidzidis Y, Brusch L, Hampe J, Schafmayer C, Zerial M (2023)
    Apical bulkheads accumulate as adaptive response to impaired bile flow in liver disease
    EMBO Rep, 24 (9), e57181
    DOI 10.15252/embr.202357181, PubMed 37522754
27. Mikaeloff F, Gelpi M, Benfeitas R, Knudsen AD, Vestad B, Høgh J, Hov JR, Benfield T, Murray D, Giske CG, Mardinoglu A, Trøseid M, Nielsen SD, Neogi U (2023)
    Network-based multi-omics integration reveals metabolic at-risk profile within treated HIV-infection
    Elife, 12
    DOI 10.7554/eLife.82785, PubMed 36794912
28. Nendl A, Raju SC, Broch K, Mayerhofer CCK, Holm K, Halvorsen B, Lappegård KT, Moscavitch S, Hov JR, Seljeflot I, Trøseid M, Awoyemi A (2023)
    Intestinal fatty acid binding protein is associated with cardiac function and gut dysbiosis in chronic heart failure
    Front Cardiovasc Med, 10, 1160030
    DOI 10.3389/fcvm.2023.1160030, PubMed 37332580
29. Oldereid TS, Jiang X, Nordhus KS, Ponzetta A, Bjørnholt JV, Björkström NK, Melum E, Rasmussen H (2023)
    Role of bacteria and microbial metabolites in immune modulation during early life
    Scand J Immunol, 99 (2), e13336
    DOI 10.1111/sji.13336, PubMed 38441196
30. Schneider KM, Kummen M, Trivedi PJ, Hov JR (2023)
    Role of microbiome in autoimmune liver diseases
    Hepatology, 80 (4), 965-987
    DOI 10.1097/HEP.0000000000000506, PubMed 37369002
31. Serra-Burriel M, Juanola A, Serra-Burriel F, Thiele M, Graupera I, Pose E, Pera G, Grgurevic I, Caballeria L, Piano S, van Kleef L, Reichert M, Roulot D, Pericàs JM, Schattenberg JM, Tsochatztis EA, Guha IN, Garcia-Retortillo M, Hernández R, Hoyo J, Fuentes M, Expósito C, Martínez A, Such P, Madir A et al. (2023)
    Development, validation, and prognostic evaluation of a risk score for long-term liver-related outcomes in the general population: a multicohort study
    Lancet, 402 (10406), 988-996
    DOI 10.1016/S0140-6736(23)01174-1, PubMed 37572680
32. Serrano-Villar S, Tincati C, Raju SC, Sáenz JS, Moreno E, Bargiela R, Cabello-Ubeda A, Sendagorta E, Kurz A, Perez Molina JA, de Benito A, Hov JR, Fernandez-Lopez L, Muriel A, Del Campo R, Moreno S, Trøseid M, Seifert J, Ferrer M (2023)
    Microbiome-derived cobalamin and succinyl-CoA as biomarkers for improved screening of anal cancer
    Nat Med, 29 (7), 1738-1749
    DOI 10.1038/s41591-023-02407-3, PubMed 37464040
33. Steiert TA, Parra G, Gut M, Arnold N, Trotta JR, Tonda R, Moussy A, Gerber Z, Abuja PM, Zatloukal K, Röcken C, Folseraas T, Grimsrud MM, Vogel A, Goeppert B, Roessler S, Hinz S, Schafmayer C, Rosenstiel P, Deleuze JF, Gut IG, Franke A, Forster M (2023)
    A critical spotlight on the paradigms of FFPE-DNA sequencing
    Nucleic Acids Res, 51 (14), 7143-7162
    DOI 10.1093/nar/gkad519, PubMed 37351572
34. Tedbury PR, Manfredi C, Degenhardt F, Conway J, Horwath MC, McCracken C, Sorscher AJ, Moreau S, Wright C, Edwards C, Brewer J, Guarner J, de Wit E, Williamson BN, Suthar MS, Ong YT, Roback JD, Alter DN, Holter JC, Karlsen TH, Sacchi N, Romero-Gómez M, Invernizzi P, Fernández J, Buti M et al. (2023)
    Mechanisms by which the cystic fibrosis transmembrane conductance regulator may influence SARS-CoV-2 infection and COVID-19 disease severity
    FASEB J, 37 (11), e23220
    DOI 10.1096/fj.202300077R, PubMed 37801035
35. Tran TT, Vaage EB, Mehta A, Chopra A, Tietze L, Kolderup A, Anthi A, König M, Nygaard G, Lind A, Müller F, Nissen-Meyer LS, Magnus P, Trogstad L, Mjaaland S, Søraas A, Midtvedt K, Åsberg A, Barratt-Due A, Medhus AW, Høivik ML, Lundin K, Karlsen RF, Dahle R, Danielsson K et al. (2023)
    Author Correction: Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
    NPJ Vaccines, 8 (1), 4
    DOI 10.1038/s41541-023-00600-6, PubMed 36697432
36. Trøseid M, Holter JC, Holm K, Vestad B, Sazonova T, Granerud BK, Dyrhol-Riise AM, Holten AR, Tonby K, Kildal AB, Heggelund L, Tveita A, Bøe S, Müller KE, Jenum S, Hov JR, Ueland T, Norwegian SARS-CoV-2 study group (2023)
    Gut microbiota composition during hospitalization is associated with 60-day mortality after severe COVID-19
    Crit Care, 27 (1), 69
    DOI 10.1186/s13054-023-04356-2, PubMed 36814280
37. Wacker EM, Uellendahl-Werth F, Bej S, Wolkenhauer O, Vesterhus M, Lieb W, Franke A, Karlsen TH, Folseraas T, Ellinghaus D (2023)
    Whole blood RNA sequencing identifies transcriptional differences between primary sclerosing cholangitis and ulcerative colitis
    JHEP Rep, 6 (2), 100988
    DOI 10.1016/j.jhepr.2023.100988, PubMed 38304234
38. Yaqub S, Bjørk I, Sugulle M, Folseraas T (2023)
    Biopsy helpful in diagnosing a liver mass in pregnancy: focal nodular hyperplasia
    Lancet, 402 (10403), e10
    DOI 10.1016/S0140-6736(23)01606-9, PubMed 37633669

Publications 2022

1. Awoniyi M, Wang J, Ngo B, Meadows V, Tam J, Viswanathan A, Lai Y, Montgomery S, Farmer M, Kummen M, Thingholm L, Schramm C, Bang C, Franke A, Lu K, Zhou H, Bajaj JS, Hylemon PB, Ting J, Popov YV, Hov JR, Francis HL, Sartor RB (2022)
   Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in a murine model of PSC
   Gut, 72 (4), 671-685
   DOI 10.1136/gutjnl-2021-326500, PubMed 35705368
2. Awoyemi A, Hov JR, Trøseid M (2022)
   Phenylacetylglutamine From the Gut Microbiota: A Future Therapeutic Target in Heart Failure?
   Circ Heart Fail, 16 (1), e010222
   DOI 10.1161/CIRCHEARTFAILURE.122.010222, PubMed 36524473
3. Bergquist A, Weismüller TJ, Levy C, Rupp C, Joshi D, Nayagam JS, Montano-Loza AJ, Lytvyak E, Wunsch E, Milkiewicz P, Zenouzi R, Schramm C, Cazzagon N, Floreani A, Liby IF, Wiestler M, Wedemeyer H, Zhou T, Strassburg CP, Rigopoulou E, Dalekos G, Narasimman M, Verhelst X, Degroote H, Vesterhus M et al. (2022)
   Impact on follow-up strategies in patients with primary sclerosing cholangitis
   Liver Int, 43 (1), 127-138
   DOI 10.1111/liv.15286, PubMed 35535655
4. Botteri E, Hoff G, Randel KR, Holme Ø, de Lange T, Bernklev T, Aas E, Berthelsen M, Natvig E, Kirkøen B, Knudsen MD, Kvaerner AS, Schult AL, Ursin G, Jørgensen A, Berstad P (2022)
   Characteristics of nonparticipants in a randomised colorectal cancer screening trial comparing sigmoidoscopy and faecal immunochemical testing
   Int J Cancer, 151 (3), 361-371
   DOI 10.1002/ijc.34025, PubMed 35411554
5. Brevini T, Maes M, Webb GJ, John BV, Fuchs CD, Buescher G, Wang L, Griffiths C, Brown ML, Scott WE, Pereyra-Gerber P, Gelson WTH, Brown S, Dillon S, Muraro D, Sharp J, Neary M, Box H, Tatham L, Stewart J, Curley P, Pertinez H, Forrest S, Mlcochova P, Varankar SS et al. (2022)
   FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2
   Nature, 615 (7950), 134-142
   DOI 10.1038/s41586-022-05594-0, PubMed 36470304
6. Braadland PR, Schneider KM, Bergquist A, Molinaro A, Lövgren-Sandblom A, Henricsson M, Karlsen TH, Vesterhus M, Trautwein C, Hov JR, Marschall HU (2022)
   Suppression of bile acid synthesis as a tipping point in the disease course of primary sclerosing cholangitis
   JHEP Rep, 4 (11), 100561
   DOI 10.1016/j.jhepr.2022.100561, PubMed 36176935
7. Chung BK, Øgaard J, Reims HM, Karlsen TH, Melum E (2022)
   Spatial transcriptomics identifies enriched gene expression and cell types in human liver fibrosis
   Hepatol Commun, 6 (9), 2538-2550
   DOI 10.1002/hep4.2001, PubMed 35726350
8. Cruz R, Diz-de Almeida S, López de Heredia M, Quintela I, Ceballos FC, Pita G, Lorenzo-Salazar JM, González-Montelongo R, Gago-Domínguez M, Sevilla Porras M, Tenorio Castaño JA, Nevado J, Aguado JM, Aguilar C, Aguilera-Albesa S, Almadana V, Almoguera B, Alvarez N, Andreu-Bernabeu Á, Arana-Arri E, Arango C, Arranz MJ, Artiga MJ, Baptista-Rosas RC, Barreda-Sánchez M et al. (2022)
   Novel genes and sex differences in COVID-19 severity
   Hum Mol Genet, 31 (22), 3789-3806
   DOI 10.1093/hmg/ddac132, PubMed 35708486
9. Degenhardt F, Ellinghaus D, Juzenas S, Lerga-Jaso J, Wendorff M, Maya-Miles D, Uellendahl-Werth F, ElAbd H, Rühlemann MC, Arora J, Özer O, Lenning OB, Myhre R, Vadla MS, Wacker EM, Wienbrandt L, Blandino Ortiz A, de Salazar A, Garrido Chercoles A, Palom A, Ruiz A, Garcia-Fernandez AE, Blanco-Grau A, Mantovani A, Zanella A et al. (2022)
   Detailed stratified GWAS analysis for severe COVID-19 in four European populations
   Hum Mol Genet, 31 (23), 3945-3966
   DOI 10.1093/hmg/ddac158, PubMed 35848942
10. Eliasson J, Lo B, Schramm C, Chazouilleres O, Folseraas T, Beuers U, Ytting H (2022)
    Survey uncovering variations in the management of primary sclerosing cholangitis across Europe
    JHEP Rep, 4 (11), 100553
    DOI 10.1016/j.jhepr.2022.100553, PubMed 36164416
11. Gelpi M, Vestad B, Raju SC, Hansen SH, Høgh J, Midttun Ø, Ueland PM, Ueland T, Benfield T, Kofoed KF, Hov JR, Trøseid M, Nielsen SD (2022)
    Association of the Kynurenine Pathway of Tryptophan Metabolism With Human Immunodeficiency Virus-Related Gut Microbiota Alterations and Visceral Adipose Tissue Accumulation
    J Infect Dis, 225 (11), 1948-1954
    DOI 10.1093/infdis/jiac018, PubMed 35089326
12. Graupera I, Thiele M, Ma AT, Serra-Burriel M, Pich J, Fabrellas N, Caballeria L, de Knegt RJ, Grgurevic I, Reichert M, Roulot D, Schattenberg JM, Pericas JM, Angeli P, Tsochatzis EA, Guha IN, Garcia-Retortillo M, Morillas RM, Hernández R, Hoyo J, Fuentes M, Madir A, Juanola A, Soria A, Juan M et al. (2022)
    LiverScreen project: study protocol for screening for liver fibrosis in the general population in European countries
    BMC Public Health, 22 (1), 1385
    DOI 10.1186/s12889-022-13724-6, PubMed 35854275
13. He MM, Lo CH, Wang K, Polychronidis G, Wang L, Zhong R, Knudsen MD, Fang Z, Song M (2022)
    Immune-Mediated Diseases Associated With Cancer Risks
    JAMA Oncol, 8 (2), 209-219
    DOI 10.1001/jamaoncol.2021.5680, PubMed 34854871
14. Helgadottir H, Folvik G, Vesterhus M (2022)
    Improvement of cholestatic episodes in patients with benign recurrent intrahepatic cholestasis (BRIC) treated with rifampicin. A long-term follow-up
    Scand J Gastroenterol, 58 (5), 512-520
    DOI 10.1080/00365521.2022.2143725, PubMed 36369734
15. Hov JR, Karlsen TH (2022)
    The microbiota and the gut-liver axis in primary sclerosing cholangitis
    Nat Rev Gastroenterol Hepatol, 20 (3), 135-154
    DOI 10.1038/s41575-022-00690-y, PubMed 36352157
16. Izquierdo-Sanchez L, Lamarca A, La Casta A, Buettner S, Utpatel K, Klümpen HJ, Adeva J, Vogel A, Lleo A, Fabris L, Ponz-Sarvise M, Brustia R, Cardinale V, Braconi C, Vidili G, Jamieson NB, Macias RI, Jonas JP, Marzioni M, Hołówko W, Folseraas T, Kupčinskas J, Sparchez Z, Krawczyk M, Krupa Ł et al. (2022)
    Cholangiocarcinoma landscape in Europe: Diagnostic, prognostic and therapeutic insights from the ENSCCA Registry
    J Hepatol, 76 (5), 1109-1121
    DOI 10.1016/j.jhep.2021.12.010, PubMed 35167909
17. Karlsen TH (2022)
    Understanding COVID-19 through genome-wide association studies
    Nat Genet, 54 (4), 368-369
    DOI 10.1038/s41588-021-00985-x, PubMed 35410380
18. Knudsen MD, Kvaerner AS, Botteri E, Holme Ø, Hjartåker A, Song M, Thiis-Evensen E, Randel KR, Hoff G, Berstad P (2022)
    Lifestyle predictors for inconsistent participation to fecal based colorectal cancer screening
    BMC Cancer, 22 (1), 172
    DOI 10.1186/s12885-022-09287-9, PubMed 35168592
19. Krag A, Karlsen TH (2022)
    [Not Available]
    Ugeskr Laeger, 184 (8)
    PubMed 35244013
20. Kaarbø M, Yang M, Hov JR, Holm K, de Sousa MML, Macpherson ME, Reims HM, Kran AB, Halvorsen B, Karlsen TH, Aukrust P, Lundin KEA, Fevang B, Bjørås M, Jørgensen SF (2022)
    Duodenal inflammation in common variable immunodeficiency has altered transcriptional response to viruses
    J Allergy Clin Immunol, 151 (3), 767-777
    DOI 10.1016/j.jaci.2022.09.029, PubMed 36220400
21. Laursen TL, Bossen L, Pihl R, Troldborg A, Sandahl TD, Hansen AG, Folserass T, Vesterhus M, Grønbæk H, Thiel S (2022)
    Highly Increased Levels of Inter-α-inhibitor Heavy Chain 4 (ITIH4) in Autoimmune Cholestatic Liver Diseases
    J Clin Transl Hepatol, 10 (5), 796-802
    DOI 10.14218/JCTH.2021.00515, PubMed 36304505
22. Lei L, Bruneau A, El Mourabit H, Guégan J, Folseraas T, Lemoinne S, Karlsen TH, Hoareau B, Morichon R, Gonzalez-Sanchez E, Goumard C, Ratziu V, Charbord P, Gautheron J, Tacke F, Jaffredo T, Cadoret A, Housset C (2022)
    Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis
    Hepatology, 76 (5), 1360-1375
    DOI 10.1002/hep.32456, PubMed 35278227
23. Meyer-Myklestad MH, Medhus AW, Lorvik KB, Seljeflot I, Hansen SH, Holm K, Stiksrud B, Trøseid M, Hov JR, Kvale D, Dyrhol-Riise AM, Kummen M, Reikvam DH (2022)
    Human Immunodeficiency Virus-Infected Immunological Nonresponders Have Colon-Restricted Gut Mucosal Immune Dysfunction
    J Infect Dis, 225 (4), 661-674
    DOI 10.1093/infdis/jiaa714, PubMed 33216130
24. Meyer-Myklestad MH, Medhus AW, Stiksrud B, Lorvik KB, Seljeflot I, Hansen SH, Holm K, Hov JR, Kvale D, Dyrhol-Riise AM, Kummen M, Trøseid M, Reikvam DH (2022)
    Probiotics to HIV-Infected Immunological Nonresponders: Altered Mucosal Immunity and Microbial Diversity Restricted to Ileum
    J Acquir Immune Defic Syndr, 89 (1), 77-86
    DOI 10.1097/QAI.0000000000002817, PubMed 34878437
25. Nooijen LE, Banales JM, de Boer MT, Braconi C, Folseraas T, Forner A, Holowko W, Hoogwater FJH, Klümpen HJ, Groot Koerkamp B, Lamarca A, La Casta A, López-López F, Izquierdo-Sánchez L, Scheiter A, Utpatel K, Swijnenburg RJ, Kazemier G, Erdmann JI,   ENSCCA Group (2022)
    Impact of Positive Lymph Nodes and Resection Margin Status on the Overall Survival of Patients with Resected Perihilar Cholangiocarcinoma: The ENSCCA Registry
    Cancers (Basel), 14 (10)
    DOI 10.3390/cancers14102389, PubMed 35625993
26. Singh Y, Jons WA, Eaton JE, Vesterhus M, Karlsen T, Bjoerk I, Abildgaard A, Jorgensen KK, Folseraas T, Little D, Gulamhusein AF, Petrovic K, Negard A, Conte GM, Sobek JD, Jagtap J, Venkatesh SK, Gores GJ, LaRusso NF, Lazaridis KN, Erickson BJ (2022)
    Algebraic topology-based machine learning using MRI predicts outcomes in primary sclerosing cholangitis
    Eur Radiol Exp, 6 (1), 58
    DOI 10.1186/s41747-022-00312-x, PubMed 36396865
27. Storm-Larsen C, Hande LN, Kummen M, Thunhaug H, Vestad B, Hansen SH, Hovland A, Trøseid M, Lappegård KT, Hov JR (2022)
    Reduced gut microbial diversity in familial hypercholesterolemia with no effect of omega-3 polyunsaturated fatty acids intervention - a pilot trial
    Scand J Clin Lab Invest, 82 (5), 363-370
    DOI 10.1080/00365513.2022.2102540, PubMed 35913798
28. Stø K, Valeur J, Ueland T, Malmstrøm GH, Bjerkeli V, Trøseid M, Hov JR, Holm K, Vestad B, Halvorsen B, Skjelland M, Skagen KR (2022)
    Fecal level of butyric acid, a microbiome-derived metabolite, is increased in patients with severe carotid atherosclerosis
    Sci Rep, 12 (1), 22378
    DOI 10.1038/s41598-022-26759-x, PubMed 36572703
29. Tran TT, Vaage EB, Mehta A, Chopra A, Tietze L, Kolderup A, Anthi A, König M, Nygaard G, Lind A, Müller F, Nissen-Meyer LS, Magnus P, Trogstad L, Mjaaland S, Søraas A, Midtvedt K, Åsberg A, Barratt-Due A, Medhus AW, Høivik ML, Lundin K, Karlsen RF, Dahle R, Danielsson K et al. (2022)
    Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
    NPJ Vaccines, 7 (1), 174
    DOI 10.1038/s41541-022-00586-7, PubMed 36585405
30. Tønnessen TC, Melleby AO, Hauge-Iversen IM, Espe EKS, Ahmed MS, Ueland T, Haavardsholm EA, Atkinson SM, Melum E, Attramadal H, Sjaastad I, Vinge LE (2022)
    Impact of delayed type hypersensitivity arthritis on development of heart failure by aortic constriction in mice
    PLoS One, 17 (1), e0262821
    DOI 10.1371/journal.pone.0262821, PubMed 35077491
31. Valestrand L, Zheng F, Hansen SH, Øgaard J, Hov JR, Björkström NK, Karlsen TH, Jiang X, Melum E (2022)
    Bile from Patients with Primary Sclerosing Cholangitis Contains Mucosal-Associated Invariant T-Cell Antigens
    Am J Pathol, 192 (4), 629-641
    DOI 10.1016/j.ajpath.2021.12.008, PubMed 35063408
32. van der Meer D, Gurholt TP, Sønderby IE, Shadrin AA, Hindley G, Rahman Z, de Lange AG, Frei O, Leinhard OD, Linge J, Simon R, Beck D, Westlye LT, Halvorsen S, Dale AM, Karlsen TH, Kaufmann T, Andreassen OA (2022)
    The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition
    Commun Biol, 5 (1), 1271
    DOI 10.1038/s42003-022-04237-4, PubMed 36402844
33. Vestad B, Ueland T, Lerum TV, Dahl TB, Holm K, Barratt-Due A, Kåsine T, Dyrhol-Riise AM, Stiksrud B, Tonby K, Hoel H, Olsen IC, Henriksen KN, Tveita A, Manotheepan R, Haugli M, Eiken R, Berg Å, Halvorsen B, Lekva T, Ranheim T, Michelsen AE, Kildal AB, Johannessen A, Thoresen L et al. (2022)
    Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterations
    J Intern Med, 291 (6), 801-812
    DOI 10.1111/joim.13458, PubMed 35212063
34. Vesterhus M (2022)
    [Good TIPS for severe liver disease]
    Tidsskr Nor Laegeforen, 142 (14)
    DOI 10.4045/tidsskr.22.0585, PubMed 36226424
35. Vesterhus M, Jørgensen KK, Frigstad SO, Haukeland JW, Karlsen TH (2022)
    [We need a new strategy for liver disease]
    Tidsskr Nor Laegeforen, 142 (3)
    DOI 10.4045/tidsskr.21.0892, PubMed 35170917
36. Wang K, Ma W, Hu Y, Knudsen MD, Nguyen LH, Wu K, Ng K, Wang M, Ogino S, Sun Q, Giovannucci EL, Chan AT, Song M (2022)
    Endoscopic Screening and Risk of Colorectal Cancer according to Type 2 Diabetes Status
    Cancer Prev Res (Phila), 15 (12), 847-856
    DOI 10.1158/1940-6207.CAPR-22-0305, PubMed 36049216
37. Wang L, Knudsen MD, Lo CH, Wang K, He M, Polychronidis G, Hang D, He X, Zhong R, Wu K, Chan AT, Ogino S, Giovannucci EL, Song M (2022)
    Adherence to a healthy lifestyle in relation to colorectal cancer incidence and all-cause mortality after endoscopic polypectomy: A prospective study in three U.S. cohorts
    Int J Cancer, 151 (9), 1523-1534
    DOI 10.1002/ijc.34176, PubMed 35716133
38. Yu J, Refsum E, Helsingen LM, Folseraas T, Ploner A, Wieszczy P, Barua I, Jodal HC, Melum E, Løberg M, Blom J, Bretthauer M, Adami HO, Kalager M, Ye W (2022)
    Risk of hepato-pancreato-biliary cancer is increased by primary sclerosing cholangitis in patients with inflammatory bowel disease: A population-based cohort study
    United European Gastroenterol J, 10 (2), 212-224
    DOI 10.1002/ueg2.12204, PubMed 35107865

Publications 2021

1. Aune D, Sen A, Norat T, Riboli E, Folseraas T (2021)
   Primary sclerosing cholangitis and the risk of cancer, cardiovascular disease, and all-cause mortality: a systematic review and meta-analysis of cohort studies
   Sci Rep, 11 (1), 10646
   DOI 10.1038/s41598-021-90175-w, PubMed 34017024
2. Awoyemi A, Mayerhofer C, Felix AS, Hov JR, Moscavitch SD, Lappegård KT, Hovland A, Halvorsen S, Halvorsen B, Gregersen I, Svardal A, Berge RK, Hansen SH, Götz A, Holm K, Aukrust P, Åkra S, Seljeflot I, Solheim S, Lorenzo A, Gullestad L, Trøseid M, Broch K (2021)
   Rifaximin or Saccharomyces boulardii in heart failure with reduced ejection fraction: Results from the randomized GutHeart trial
   EBioMedicine, 70, 103511
   DOI 10.1016/j.ebiom.2021.103511, PubMed 34329947
3. Bossen L, Vesterhus M, Hov JR, Färkkilä M, Rosenberg WM, Møller HJ, Boberg KM, Karlsen TH, Grønbæk H (2021)
   Circulating Macrophage Activation Markers Predict Transplant-Free Survival in Patients With Primary Sclerosing Cholangitis
   Clin Transl Gastroenterol, 12 (3), e00315
   DOI 10.14309/ctg.0000000000000315, PubMed 33646203
4. COVID-19 Host Genetics Initiative (2021)
   Mapping the human genetic architecture of COVID-19
   Nature, 600 (7889), 472-477
   DOI 10.1038/s41586-021-03767-x, PubMed 34237774
5. Degenhardt F, Mayr G, Wendorff M, Boucher G, Ellinghaus E, Ellinghaus D, ElAbd H, Rosati E, Hübenthal M, Juzenas S, Abedian S, Vahedi H, Thelma BK, Yang SK, Ye BD, Cheon JH, Datta LW, Daryani NE, Ellul P, Esaki M, Fuyuno Y, McGovern DPB, Haritunians T, Hong M, Juyal G et al. (2021)
   Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations
   Hum Mol Genet, 30 (5), 356-369
   DOI 10.1093/hmg/ddab017, PubMed 33555323
6. Dhillon AK, Rupp C, Bergquist A, Voitl R, Folseraas T, Trøseid M, Midttun Ø, Ueland PM, Karlsen TH, Vesterhus M, Kummen M, Hov JR (2021)
   Associations of neopterin and kynurenine-tryptophan ratio with survival in primary sclerosing cholangitis
   Scand J Gastroenterol, 56 (4), 443-452
   DOI 10.1080/00365521.2021.1880627, PubMed 33583308
7. Fossdal G, Mjelle AB, Wiencke K, Bjørk I, Gilja OH, Folseraas T, Karlsen TH, Rosenberg W, Giil LM, Vesterhus M (2021)
   Fluctuating biomarkers in primary sclerosing cholangitis: A longitudinal comparison of alkaline phosphatase, liver stiffness, and ELF
   JHEP Rep, 3 (5), 100328
   DOI 10.1016/j.jhepr.2021.100328, PubMed 34485881
8. Hausken J, Haugaa H, Hagness M, Line PD, Melum E, Tønnessen TI (2021)
   Thoracic Epidural Analgesia for Postoperative Pain Management in Liver Transplantation: A 10-year Study on 685 Liver Transplant Recipients
   Transplant Direct, 7 (2), e648
   DOI 10.1097/TXD.0000000000001101, PubMed 33437863
9. Jiang X, Bergquist A, Löscher BS, Venkatesh G, Mold JE, Holm K, Laerdahl JK, Skånland SS, Maleki KT, Cornillet M, Taskén K, Franke A, Karlsen TH, Björkström NK, Melum E (2021)
   A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
   Sci Transl Med, 13 (582)
   DOI 10.1126/scitranslmed.abb0036, PubMed 33627483
10. Jiang X, Melum E (2021)
    The Role of Natural Killer Cells in Nonalcoholic Steatohepatitis: An Ongoing Debate
    Cell Mol Gastroenterol Hepatol, 13 (1), 348-349
    DOI 10.1016/j.jcmgh.2021.10.006, PubMed 34740615
11. Karlsen TH, Sheron N, Zelber-Sagi S, Carrieri P, Dusheiko G, Bugianesi E, Pryke R, Hutchinson SJ, Sangro B, Martin NK, Cecchini M, Dirac MA, Belloni A, Serra-Burriel M, Ponsioen CY, Sheena B, Lerouge A, Devaux M, Scott N, Hellard M, Verkade HJ, Sturm E, Marchesini G, Yki-Järvinen H, Byrne CD et al. (2021)
    The EASL-Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality
    Lancet, 399 (10319), 61-116
    DOI 10.1016/S0140-6736(21)01701-3, PubMed 34863359
12. Karlsen TR, Kong XY, Holm S, Quiles-Jiménez A, Dahl TB, Yang K, Sagen EL, Skarpengland T, S Øgaard JD, Holm K, Vestad B, Olsen MB, Aukrust P, Bjørås M, Hov JR, Halvorsen B, Gregersen I (2021)
    NEIL3-deficiency increases gut permeability and contributes to a pro-atherogenic metabolic phenotype
    Sci Rep, 11 (1), 19749
    DOI 10.1038/s41598-021-98820-0, PubMed 34611194
13. Knudsen MD, Wang L, Wang K, Wu K, Ogino S, Chan AT, Giovannucci E, Song M (2021)
    Changes in Lifestyle Factors After Endoscopic Screening: A Prospective Study in the United States
    Clin Gastroenterol Hepatol, 20 (6), e1240-e1249
    DOI 10.1016/j.cgh.2021.07.014, PubMed 34256146
14. Lamarca A, Santos-Laso A, Utpatel K, La Casta A, Stock S, Forner A, Adeva J, Folseraas T, Fabris L, Macias RIR, Krawczyk M, Krawczyk M, Cardinale V, Braconi C, Alvaro D, Evert M, Banales JM, Valle JW (2021)
    REPLY
    Hepatology, 74 (2), 1129-1131
    DOI 10.1002/hep.31740, PubMed 33550618
15. Lamarca A, Santos-Laso A, Utpatel K, La Casta A, Stock S, Forner A, Adeva J, Folseraas T, Fabris L, Macias RIR, Krawczyk M, Krawczyk M, Cardinale V, Braconi C, Alvaro D, Evert M, Banales JM, Valle JW (2021)
    Letter to the Editor: Does Multiple Intrahepatic Cholangiocarcinoma Worsen Prognosis as "M1" Stage? REPLY
    Hepatology, 74 (2), 1129-1131
    DOI 10.1002/hep.31740
16. Lamarca A, Santos-Laso A, Utpatel K, La Casta A, Stock S, Forner A, Adeva J, Folseraas T, Fabris L, Macias RIR, Krawczyk M, Krawczyk M, Cardinale V, Braconi C, Alvaro D, Evert M, Banales JM, Valle JW, Group: on behalf of the European Network for the Study of Cholangiocarcinoma (ENS-CCA) (2021)
    Liver Metastases of Intrahepatic Cholangiocarcinoma: Implications for an Updated Staging System
    Hepatology, 73 (6), 2311-2325
    DOI 10.1002/hep.31598, PubMed 33073396
17. Lissing M, Nowak G, Adam R, Karam V, Boyd A, Gouya L, Meersseman W, Melum E, Ołdakowska-Jedynak U, Reiter FP, Colmenero J, Sanchez R, Herden U, Langendonk J, Ventura P, Isoniemi H, Boillot O, Braun F, Perrodin S, Mowlem E, Wahlin S, European Liver and Intestine Transplant Association (2021)
    Liver Transplantation for Acute Intermittent Porphyria
    Liver Transpl, 27 (4), 491-501
    DOI 10.1002/lt.25959, PubMed 33259654
18. Mousa OY, Juran BD, McCauley BM, Vesterhus MN, Folseraas T, Turgeon CT, Ali AH, Schlicht EM, Atkinson EJ, Hu C, Harnois D, Carey EJ, Gossard AA, Oglesbee D, Eaton JE, LaRusso NF, Gores GJ, Karlsen TH, Lazaridis KN (2021)
    Bile Acid Profiles in Primary Sclerosing Cholangitis and Their Ability to Predict Hepatic Decompensation
    Hepatology, 74 (1), 281-295
    DOI 10.1002/hep.31652, PubMed 33226645
19. Nakanishi T, Pigazzini S, Degenhardt F, Cordioli M, Butler-Laporte G, Maya-Miles D, Bujanda L, Bouysran Y, Niemi ME, Palom A, Ellinghaus D, Khan A, Martínez-Bueno M, Rolker S, Amitrano S, Roade Tato L, Fava F, FinnGen, COVID-19 Host Genetics Initiative (HGI), Spinner CD, Prati D, Bernardo D, Garcia F, Darcis G, Fernández-Cadenas I et al. (2021)
    Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality
    J Clin Invest, 131 (23)
    DOI 10.1172/JCI152386, PubMed 34597274
20. Nakanishi T, Pigazzini S, Degenhardt F, Cordioli M, Butler-Laporte G, Maya-Miles D, Nafría-Jiménez B, Bouysran Y, Niemi M, Palom A, Ellinghaus D, Khan A, Martínez-Bueno M, Rolker S, Amitano S, Tato LR, FinnGen, The COVID-19 Host Genetics Initiative, Fava F, Spinner CD, Prati D, Bernardo D, Garcia F, Darcis G, Fernández-Cadenas I, Holter JC et al. (2021)
    Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality
    medRxiv
    DOI 10.1101/2021.03.07.21252875, PubMed 33758887
21. Pagano E, Elias JE, Schneditz G, Saveljeva S, Holland LM, Borrelli F, Karlsen TH, Kaser A, Kaneider NC (2021)
    Activation of the GPR35 pathway drives angiogenesis in the tumour microenvironment
    Gut, 71 (3), 509-520
    DOI 10.1136/gutjnl-2020-323363, PubMed 33758004
22. Polychronidis G, Wang K, Lo CH, Wang L, He M, Knudsen MD, Wu K, Joshi AD, Ogino S, Giovannucci EL, Chan AT, Song M (2021)
    Gallstone Disease and Risk of Conventional Adenomas and Serrated Polyps: A Prospective Study
    Cancer Epidemiol Biomarkers Prev, 30 (12), 2346-2349
    DOI 10.1158/1055-9965.EPI-21-0515, PubMed 34620626
23. Reich M, Spomer L, Klindt C, Fuchs K, Stindt J, Deutschmann K, Höhne J, Liaskou E, Hov JR, Karlsen TH, Beuers U, Verheij J, Ferreira-Gonzalez S, Hirschfield G, Forbes SJ, Schramm C, Esposito I, Nierhoff D, Fickert P, Fuchs CD, Trauner M, García-Beccaria M, Gabernet G, Nahnsen S, Mallm JP et al. (2021)
    Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis
    J Hepatol, 75 (3), 634-646
    DOI 10.1016/j.jhep.2021.03.029, PubMed 33872692
24. Sampaziotis F, Muraro D, Tysoe OC, Sawiak S, Beach TE, Godfrey EM, Upponi SS, Brevini T, Wesley BT, Garcia-Bernardo J, Mahbubani K, Canu G, Gieseck R, Berntsen NL, Mulcahy VL, Crick K, Fear C, Robinson S, Swift L, Gambardella L, Bargehr J, Ortmann D, Brown SE, Osnato A, Murphy MP et al. (2021)
    Cholangiocyte organoids can repair bile ducts after transplantation in the human liver
    Science, 371 (6531), 839-846
    DOI 10.1126/science.aaz6964, PubMed 33602855
25. Schneider KM, Candels LS, Hov JR, Myllys M, Hassan R, Schneider CV, Wahlström A, Mohs A, Zühlke S, Liao L, Elfers C, Kilic K, Henricsson M, Molinaro A, Hatting M, Zaza A, Drasdo D, Frissen M, Devlin AS, Gálvez EJC, Strowig T, Karlsen TH, Hengstler JG, Marschall HU, Ghallab A et al. (2021)
    Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling
    Nat Metab, 3 (9), 1228-1241
    DOI 10.1038/s42255-021-00452-1, PubMed 34552267
26. Skarpengland T, Macpherson ME, Hov JR, Kong XY, Bohov P, Halvorsen B, Fevang B, Berge RK, Aukrust P, Jørgensen SF (2021)
    Altered Plasma Fatty Acids Associate with Gut Microbial Composition in Common Variable Immunodeficiency
    J Clin Immunol, 42 (1), 146-157
    DOI 10.1007/s10875-021-01146-9, PubMed 34669143
27. Skaarud KJ, Hov JR, Hansen SH, Kummen M, Valeur J, Seljeflot I, Bye A, Paulsen V, Lundin KEA, Trøseid M, Tjønnfjord GE, Iversen PO (2021)
    Mortality and microbial diversity after allogeneic hematopoietic stem cell transplantation: secondary analysis of a randomized nutritional intervention trial
    Sci Rep, 11 (1), 11593
    DOI 10.1038/s41598-021-90976-z, PubMed 34078971
28. Vedeld HM, Grimsrud MM, Andresen K, Pharo HD, von Seth E, Karlsen TH, Honne H, Paulsen V, Färkkilä MA, Bergquist A, Jeanmougin M, Aabakken L, Boberg KM, Folseraas T, Lind GE (2021)
    Early and accurate detection of cholangiocarcinoma in patients with primary sclerosing cholangitis by methylation markers in bile
    Hepatology, 75 (1), 59-73
    DOI 10.1002/hep.32125, PubMed 34435693
29. Vestad B, Nyman TA, Hove-Skovsgaard M, Stensland M, Hoel H, Trøseid AS, Aspelin T, Aass HCD, Puhka M, Hov JR, Nielsen SD, Øvstebø R, Trøseid M (2021)
    Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk
    Sci Rep, 11 (1), 21936
    DOI 10.1038/s41598-021-01334-y, PubMed 34754007
30. Vesterhus M, Wiencke K, Haukeland JW, Frigstad SO, Karlsen LN, Jørgensen KK, Folseraas T (2021)
    [Diagnosis and treatment of autoimmune hepatitis]
    Tidsskr Nor Laegeforen, 141 (10)
    DOI 10.4045/tidsskr.20.1045, PubMed 34182737
31. Zimmer CL, Filipovic I, Cornillet M, O'Rourke CJ, Berglin L, Jansson H, Sun D, Strauss O, Hertwig L, Johansson H, von Seth E, Sparrelid E, Dias J, Glaumann H, Melum E, Ellis EC, Sandberg JK, Andersen JB, Bergquist A, Björkström NK (2021)
    Mucosal-associated invariant T-cell tumor infiltration predicts long-term survival in cholangiocarcinoma
    Hepatology, 75 (5), 1154-1168
    DOI 10.1002/hep.32222, PubMed 34719787
32. Zimmer CL, von Seth E, Buggert M, Strauss O, Hertwig L, Nguyen S, Wong AYW, Zotter C, Berglin L, Michaëlsson J, Hansson MR, Arnelo U, Sparrelid E, Ellis ECS, Söderholm JD, Keita ÅV, Holm K, Özenci V, Hov JR, Mold JE, Cornillet M, Ponzetta A, Bergquist A, Björkström NK (2021)
    A biliary immune landscape map of primary sclerosing cholangitis reveals a dominant network of neutrophils and tissue-resident T cells
    Sci Transl Med, 13 (599)
    DOI 10.1126/scitranslmed.abb3107, PubMed 34162753

Publications 2020

1. Deeb M, Karlsen TH, Hirschfield GM (2020)
   The 6 C's of primary sclerosing cholangitis
   J Hepatol, 73 (5), 1255-1256
   DOI 10.1016/j.jhep.2020.06.033, PubMed 32649970
2. Derer S, Brethack AK, Pietsch C, Jendrek ST, Nitzsche T, Bokemeyer A, Hov JR, Schäffler H, Bettenworth D, Grassl GA, Sina C (2020)
   Inflammatory Bowel Disease-associated GP2 Autoantibodies Inhibit Mucosal Immune Response to Adherent-invasive Bacteria
   Inflamm Bowel Dis, 26 (12), 1856-1868
   DOI 10.1093/ibd/izaa069, PubMed 32304568
3. Fretheim H, Chung BK, Didriksen H, Bækkevold ES, Midtvedt Ø, Brunborg C, Holm K, Valeur J, Tennøe AH, Garen T, Midtvedt T, Trøseid M, Zarè H, Lund MB, Hov JR, Lundin KEA, Molberg Ø, Hoffmann-Vold AM (2020)
   Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
   PLoS One, 15 (5), e0232739
   DOI 10.1371/journal.pone.0232739, PubMed 32437393
4. Gelpi M, Vestad B, Hansen SH, Holm K, Drivsholm N, Goetz A, Kirkby NS, Lindegaard B, Lebech AM, Hoel H, Michelsen AE, Ueland T, Gerstoft J, Lundgren J, Hov JR, Nielsen SD, Trøseid M (2020)
   Impact of Human Immunodeficiency Virus-Related Gut Microbiota Alterations on Metabolic Comorbid Conditions
   Clin Infect Dis, 71 (8), e359-e367
   DOI 10.1093/cid/ciz1235, PubMed 31894240
5. Goeppert B, Folseraas T, Roessler S, Kloor M, Volckmar AL, Endris V, Buchhalter I, Stenzinger A, Grzyb K, Grimsrud MM, Gornicka B, von Seth E, Reynolds GM, Franke A, Gotthardt DN, Mehrabi A, Cheung A, Verheij J, Arola J, Mäkisalo H, Eide TJ, Weidemann S, Cheville JC, Mazza G, Hirschfield GM et al. (2020)
   Genomic Characterization of Cholangiocarcinoma in Primary Sclerosing Cholangitis Reveals Therapeutic Opportunities
   Hepatology, 72 (4), 1253-1266
   DOI 10.1002/hep.31110, PubMed 31925805
6. He MM, Fang Z, Hang D, Wang F, Polychronidis G, Wang L, Lo CH, Wang K, Zhong R, Knudsen MD, Smith SG, Xu RH, Song M (2020)
   Circulating liver function markers and colorectal cancer risk: A prospective cohort study in the UK Biobank
   Int J Cancer, 148 (8), 1867-1878
   DOI 10.1002/ijc.33351, PubMed 33091956
7. Knudsen MD, Botteri E, Holme Ø, Hjartåker A, Song M, Thiis-Evensen E, Norvard ER, Schult AL, Randel KR, Hoff G, Berstad P (2020)
   Association between lifestyle and site-specific advanced colorectal lesions in screening with faecal immunochemical test and sigmoidoscopy
   Dig Liver Dis, 53 (3), 353-359
   DOI 10.1016/j.dld.2020.11.021, PubMed 33309513
8. Kovaleva TF, Maksimova NS, Pchelin PV, Pershin VI, Tkachenko NM, Gainullin MR, Mukhina IV (2020)
   A New Cofilin-Dependent Mechanism for the Regulation of Brain Mitochondria Biogenesis and Degradation
   Sovrem Tekhnologii Med, 12 (1), 6-13
   DOI 10.17691/stm2020.12.1.01, PubMed 34513032
9. Kummen M, Solberg OG, Storm-Larsen C, Holm K, Ragnarsson A, Trøseid M, Vestad B, Skårdal R, Yndestad A, Ueland T, Svardal A, Berge RK, Seljeflot I, Gullestad L, Karlsen TH, Aaberge L, Aukrust P, Hov JR (2020)
   Rosuvastatin alters the genetic composition of the human gut microbiome
   Sci Rep, 10 (1), 5397
   DOI 10.1038/s41598-020-62261-y, PubMed 32214138
10. Kummen M, Thingholm LB, Rühlemann MC, Holm K, Hansen SH, Moitinho-Silva L, Liwinski T, Zenouzi R, Storm-Larsen C, Midttun Ø, McCann A, Ueland PM, Høivik ML, Vesterhus M, Trøseid M, Laudes M, Lieb W, Karlsen TH, Bang C, Schramm C, Franke A, Hov JR (2020)
    Altered Gut Microbial Metabolism of Essential Nutrients in Primary Sclerosing Cholangitis
    Gastroenterology, 160 (5), 1784-1798.e0
    DOI 10.1053/j.gastro.2020.12.058, PubMed 33387530
11. Lapitz A, Arbelaiz A, O'Rourke CJ, Lavin JL, Casta A, Ibarra C, Jimeno JP, Santos-Laso A, Izquierdo-Sanchez L, Krawczyk M, Perugorria MJ, Jimenez-Aguero R, Sanchez-Campos A, Riaño I, Gónzalez E, Lammert F, Marzioni M, Macias RIR, Marin JJG, Karlsen TH, Bujanda L, Falcón-Pérez JM, Andersen JB, Aransay AM, Rodrigues PM et al. (2020)
    Patients with Cholangiocarcinoma Present Specific RNA Profiles in Serum and Urine Extracellular Vesicles Mirroring the Tumor Expression: Novel Liquid Biopsy Biomarkers for Disease Diagnosis
    Cells, 9 (3)
    DOI 10.3390/cells9030721, PubMed 32183400
12. Lo CH, Kwon S, Wang L, Polychronidis G, Knudsen MD, Zhong R, Cao Y, Wu K, Ogino S, Giovannucci EL, Chan AT, Song M (2020)
    Periodontal disease, tooth loss, and risk of oesophageal and gastric adenocarcinoma: a prospective study
    Gut, 70 (3), 620-621
    DOI 10.1136/gutjnl-2020-321949, PubMed 32690603
13. Lohse AW, Sebode M, Jørgensen MH, Ytting H, Karlsen TH, Kelly D, Manns MP, Vesterhus M, European Reference Network on Hepatological Diseases (ERN RARE-LIVER), International Autoimmune Hepatitis Group (IAIHG) (2020)
    Second-line and third-line therapy for autoimmune hepatitis: A position statement from the European Reference Network on Hepatological Diseases and the International Autoimmune Hepatitis Group
    J Hepatol, 73 (6), 1496-1506
    DOI 10.1016/j.jhep.2020.07.023, PubMed 32707224
14. Lohse AW, Sebode M, Vesterhus M (2020)
    Reply to: "Both tacrolimus and mycophenylate mophetil should be considered second-line therapy for autoimmune hepatitis"
    J Hepatol, 74 (3), 755-756
    DOI 10.1016/j.jhep.2020.11.031, PubMed 33309116
15. Louwe MC, Olsen MB, Kaasbøll OJ, Yang K, Fosshaug LE, Alfsnes K, Øgaard JDS, Rashidi A, Skulberg VM, Yang M, de Miranda Fonseca D, Sharma A, Aronsen JM, Schrumpf E, Ahmed MS, Dahl CP, Nyman TA, Ueland T, Melum E, Halvorsen BE, Bjørås M, Attramadal H, Sjaastad I, Aukrust P, Yndestad A (2020)
    Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction
    JACC Basic Transl Sci, 5 (12), 1210-1224
    DOI 10.1016/j.jacbts.2020.09.013, PubMed 33426377
16. Macpherson ME, Hov JR, Ueland T, Dahl TB, Kummen M, Otterdal K, Holm K, Berge RK, Mollnes TE, Trøseid M, Halvorsen B, Aukrust P, Fevang B, Jørgensen SF (2020)
    Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency
    Front Immunol, 11, 574500
    DOI 10.3389/fimmu.2020.574500, PubMed 33042155
17. Mayerhofer CCK, Kummen M, Holm K, Broch K, Awoyemi A, Vestad B, Storm-Larsen C, Seljeflot I, Ueland T, Bohov P, Berge RK, Svardal A, Gullestad L, Yndestad A, Aukrust P, Hov JR, Trøseid M (2020)
    Low fibre intake is associated with gut microbiota alterations in chronic heart failure
    ESC Heart Fail, 7 (2), 456-466
    DOI 10.1002/ehf2.12596, PubMed 31978943
18. Mjelle AB, Fossdal G, Gilja OH, Vesterhus M (2020)
    Liver Elastography in Primary Sclerosing Cholangitis Patients Using Three Different Scanner Systems
    Ultrasound Med Biol, 46 (8), 1854-1864
    DOI 10.1016/j.ultrasmedbio.2020.03.025, PubMed 32507342
19. Severe Covid-19 GWAS Group, Ellinghaus D, Degenhardt F, Bujanda L, Buti M, Albillos A, Invernizzi P, Fernández J, Prati D, Baselli G, Asselta R, Grimsrud MM, Milani C, Aziz F, Kässens J, May S, Wendorff M, Wienbrandt L, Uellendahl-Werth F, Zheng T, Yi X, de Pablo R, Chercoles AG, Palom A, Garcia-Fernandez AE et al. (2020)
    Genomewide Association Study of Severe Covid-19 with Respiratory Failure
    N Engl J Med, 383 (16), 1522-1534
    DOI 10.1056/NEJMoa2020283, PubMed 32558485
20. Sokolova M, Yang K, Hansen SH, Louwe MC, Kummen M, Hov JER, Sjaastad I, Berge RK, Halvorsen B, Aukrust P, Yndestad A, Ranheim T (2020)
    NLRP3 inflammasome deficiency attenuates metabolic disturbances involving alterations in the gut microbial profile in mice exposed to high fat diet
    Sci Rep, 10 (1), 21006
    DOI 10.1038/s41598-020-76497-1, PubMed 33273482
21. Taraldsen V, Tomasgard S, Rudlang M, Gilja O, Vesterhus M, Mjelle A (2020)
    Point Shear Wave Elastography and the Effect of Physical Exercise, Alcohol Consumption, and Respiration in Healthy Adults
    Ultrasound Int Open, 6 (3), E54-E61
    DOI 10.1055/a-1298-9642, PubMed 33305164
22. Taraldsen V, Tomasgard S, Rudlang MT, Gilja OH, Vesterhus M, Mjelle AB (2020)
    Correction: Point Shear Wave Elastography and the Effect of Physical Exercise, Alcohol Consumption, and Respiration in Healthy Adults
    Ultrasound Int Open, 6 (3), E66
    DOI 10.1055/a-1340-1260, PubMed 33426423
23. Thaventhiran JED, Lango Allen H, Burren OS, Rae W, Greene D, Staples E, Zhang Z, Farmery JHR, Simeoni I, Rivers E, Maimaris J, Penkett CJ, Stephens J, Deevi SVV, Sanchis-Juan A, Gleadall NS, Thomas MJ, Sargur RB, Gordins P, Baxendale HE, Brown M, Tuijnenburg P, Worth A, Hanson S, Linger RJ et al. (2020)
    Whole-genome sequencing of a sporadic primary immunodeficiency cohort
    Nature, 583 (7814), 90-95
    DOI 10.1038/s41586-020-2265-1, PubMed 32499645
24. Thaventhiran JED, Lango Allen H, Burren OS, Rae W, Greene D, Staples E, Zhang Z, Farmery JHR, Simeoni I, Rivers E, Maimaris J, Penkett CJ, Stephens J, Deevi SVV, Sanchis-Juan A, Gleadall NS, Thomas MJ, Sargur RB, Gordins P, Baxendale HE, Brown M, Tuijnenburg P, Worth A, Hanson S, Linger RJ et al. (2020)
    Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort
    Nature, 584 (7819), E2
    DOI 10.1038/s41586-020-2556-6, PubMed 32678341
25. Trimboli P, Castellana M, Virili C, Havre RF, Bini F, Marinozzi F, D'Ambrosio F, Giorgino F, Giovanella L, Prosch H, Grani G, Radzina M, Cantisani V (2020)
    Performance of contrast-enhanced ultrasound (CEUS) in assessing thyroid nodules: a systematic review and meta-analysis using histological standard of reference
    Radiol Med, 125 (4), 406-415
    DOI 10.1007/s11547-019-01129-2, PubMed 31970579
26. Valestrand L, Berntsen NL, Zheng F, Schrumpf E, Hansen SH, Karlsen TH, Blumberg RS, Hov JR, Jiang X, Melum E (2020)
    Lipid antigens in bile from patients with chronic liver diseases activate natural killer T cells
    Clin Exp Immunol, 203 (2), 304-314
    DOI 10.1111/cei.13541, PubMed 33089489
27. Vedeld HM, Folseraas T, Lind GE (2020)
    Detecting cholangiocarcinoma in patients with primary sclerosing cholangitis - The promise of DNA methylation and molecular biomarkers
    JHEP Rep, 2 (5), 100143
    DOI 10.1016/j.jhepr.2020.100143, PubMed 32939446
28. Vesterhus M, Karlsen TH (2020)
    Emerging therapies in primary sclerosing cholangitis: pathophysiological basis and clinical opportunities
    J Gastroenterol, 55 (6), 588-614
    DOI 10.1007/s00535-020-01681-z, PubMed 32222826
29. Vesterhus M, Nielsen MJ, Hov JR, Saffioti F, Manon-Jensen T, Leeming DJ, Moum B, Boberg KM, Pinzani M, Karlsen TH, Karsdal MA, Thorburn D (2020)
    Comprehensive assessment of ECM turnover using serum biomarkers establishes PBC as a high-turnover autoimmune liver disease
    JHEP Rep, 3 (1), 100178
    DOI 10.1016/j.jhepr.2020.100178, PubMed 33225252

Publications 2019

1. Balashova A, Pershin V, Zaborskaya O, Tkachenko N, Mironov A, Guryev E, Kurbatov L, Gainullin M, Mukhina I (2019)
   Enzymatic Digestion of Hyaluronan-Based Brain Extracellular Matrix in vivo Can Induce Seizures in Neonatal Mice
   Front Neurosci, 13, 1033
   DOI 10.3389/fnins.2019.01033, PubMed 31632233
2. Dhillon AK, Kremer AE, Kummen M, Boberg KM, Elferink RPO, Karlsen TH, Beuers U, Vesterhus M, Hov JR (2019)
   Autotaxin activity predicts transplant-free survival in primary sclerosing cholangitis
   Sci Rep, 9 (1), 8450
   DOI 10.1038/s41598-019-44762-7, PubMed 31186435
3. Goode EC, Clark AB, Mells GF, Srivastava B, Spiess K, Gelson WTH, Trivedi PJ, Lynch KD, Castren E, Vesterhus MN, Karlsen TH, Ji SG, Anderson CA, Thorburn D, Hudson M, Heneghan MA, Aldersley MA, Bathgate A, Sandford RN, Alexander GJ, Chapman RW, Walmsley M, UK-PSC Consortium, Hirschfield GM, Rushbrook SM (2019)
   Factors Associated With Outcomes of Patients With Primary Sclerosing Cholangitis and Development and Validation of a Risk Scoring System
   Hepatology, 69 (5), 2120-2135
   DOI 10.1002/hep.30479, PubMed 30566748
4. Grimsrud MM, Brekke M, Syse VL, Vallersnes OM (2019)
   Acute poisoning related to the recreational use of prescription drugs: an observational study from Oslo, Norway
   BMC Emerg Med, 19 (1), 55
   DOI 10.1186/s12873-019-0271-0, PubMed 31615421
5. Grimsrud MM, Folseraas T (2019)
   Pathogenesis, diagnosis and treatment of premalignant and malignant stages of cholangiocarcinoma in primary sclerosing cholangitis
   Liver Int, 39 (12), 2230-2237
   DOI 10.1111/liv.14180, PubMed 31216595
6. Hole MJ (2019)
   [Fulminant bureaucratitis in junior doctors’ titles]
   Tidsskr Nor Laegeforen, 139 (7)
   DOI 10.4045/tidsskr.19.0176, PubMed 30969047
7. Hov JR (2019)
   Editorial: proton pump inhibition - microbial complications beyond dysbiosis
   Aliment Pharmacol Ther, 50 (8), 962-963
   DOI 10.1111/apt.15495, PubMed 31591776
8. Jørgensen SF, Holm K, Macpherson ME, Storm-Larsen C, Kummen M, Fevang B, Aukrust P, Hov JR (2019)
   Selective IgA deficiency in humans is associated with reduced gut microbial diversity
   J Allergy Clin Immunol, 143 (5), 1969-1971.e11
   DOI 10.1016/j.jaci.2019.01.019, PubMed 30707969
9. Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B (2019)
   Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
   Sci Rep, 9 (1), 167 (Retracted)
   DOI 10.1038/s41598-018-35367-7, PubMed 30655568
10. Karlsen TH, Newsome PN (2019)
    The dawn of a new EASL - A new chapter in the history of the European Association for the Study of the liver
    J Hepatol, 71 (1), 5-8
    DOI 10.1016/j.jhep.2019.03.010, PubMed 31056366
11. Kummen M, Hov JR (2019)
    The gut microbial influence on cholestatic liver disease
    Liver Int, 39 (7), 1186-1196
    DOI 10.1111/liv.14153, PubMed 31125502
12. Liwinski T, Zenouzi R, John C, Ehlken H, Rühlemann MC, Bang C, Groth S, Lieb W, Kantowski M, Andersen N, Schachschal G, Karlsen TH, Hov JR, Rösch T, Lohse AW, Heeren J, Franke A, Schramm C (2019)
    Alterations of the bile microbiome in primary sclerosing cholangitis
    Gut, 69 (4), 665-672
    DOI 10.1136/gutjnl-2019-318416, PubMed 31243055
13. Lunder AK, Bakstad LT, Jahnsen J, Borthne A, Hov JR, Vatn M, Negård A (2019)
    Assessment of Bowel Inflammation and Strictures by Magnetic Resonance Enterography in Long-term Crohn's Disease
    J Crohns Colitis, 13 (5), 607-614
    DOI 10.1093/ecco-jcc/jjy208, PubMed 30541145
14. Maroni L, Pinto C, Giordano DM, Saccomanno S, Banales JM, Spallacci D, Albertini MC, Orlando F, Provinciali M, Milkiewicz M, Melum E, Labiano I, Milkiewicz P, Rychlicki C, Trozzi L, Scarpelli M, Benedetti A, Svegliati Baroni G, Marzioni M (2019)
    Aging-Related Expression of Twinfilin-1 Regulates Cholangiocyte Biological Response to Injury
    Hepatology, 70 (3), 883-898
    DOI 10.1002/hep.30466, PubMed 30561764
15. Mayerhofer CCK, Awoyemi A, Hov JR, Trøseid M, Broch K (2019)
    Reply: Potential risk associated with direct modulation of the gut flora in patients with heart failure
    ESC Heart Fail, 6 (3), 557-558
    DOI 10.1002/ehf2.12437, PubMed 31034162
16. Mazzawi T, Hausken T, Hov JR, Valeur J, Sangnes DA, El-Salhy M, Gilja OH, Hatlebakk JG, Lied GA (2019)
    Clinical response to fecal microbiota transplantation in patients with diarrhea-predominant irritable bowel syndrome is associated with normalization of fecal microbiota composition and short-chain fatty acid levels
    Scand J Gastroenterol, 54 (6), 690-699
    DOI 10.1080/00365521.2019.1624815, PubMed 31190584
17. Melum E, Jiang X, Baker KD, Macedo MF, Fritsch J, Dowds CM, Wang J, Pharo A, Kaser A, Tan C, Pereira CS, Kelly SL, Duan J, Karlsen TH, Exley MA, Schütze S, Zajonc DM, Merrill AH, Schuchman EH, Zeissig S, Blumberg RS (2019)
    Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin
    Nat Immunol, 20 (12), 1644-1655
    DOI 10.1038/s41590-019-0504-0, PubMed 31636468
18. Mjelle AB, Mulabecirovic A, Havre RF, Rosendahl K, Juliusson PB, Olafsdottir E, Gilja OH, Vesterhus M (2019)
    Normal Liver Stiffness Values in Children: A Comparison of Three Different Elastography Methods
    J Pediatr Gastroenterol Nutr, 68 (5), 706-712
    DOI 10.1097/MPG.0000000000002320, PubMed 30889132
19. Mjåland O, Nygaard A, Storm-Larsen C, Brommeland T (2019)
    Cycling-related injuries at Sørlandet Hospital, Kristiansand
    Tidsskr Nor Laegeforen, 139 (12)
    DOI 10.4045/tidsskr.19.0142, PubMed 31502796
20. Rühlemann M, Liwinski T, Heinsen FA, Bang C, Zenouzi R, Kummen M, Thingholm L, Tempel M, Lieb W, Karlsen T, Lohse A, Hov J, Denk G, Lammert F, Krawczyk M, Schramm C, Franke A (2019)
    Consistent alterations in faecal microbiomes of patients with primary sclerosing cholangitis independent of associated colitis
    Aliment Pharmacol Ther, 50 (5), 580-589
    DOI 10.1111/apt.15375, PubMed 31250469
21. Rühlemann MC, Solovjeva MEL, Zenouzi R, Liwinski T, Kummen M, Lieb W, Hov JR, Schramm C, Franke A, Bang C (2019)
    Gut mycobiome of primary sclerosing cholangitis patients is characterised by an increase of Trichocladium griseum and Candida species
    Gut, 69 (10), 1890-1892
    DOI 10.1136/gutjnl-2019-320008, PubMed 31653787
22. Saffioti F, Roccarina D, Vesterhus M, Hov JR, Rosenberg W, Pinzani M, Pereira SP, Boberg KM, Thorburn D (2019)
    Cholangiocarcinoma is associated with a raised enhanced liver fibrosis score independent of primary sclerosing cholangitis
    Eur J Clin Invest, 49 (5), e13088
    DOI 10.1111/eci.13088, PubMed 30762236
23. Schneditz G, Elias JE, Pagano E, Zaeem Cader M, Saveljeva S, Long K, Mukhopadhyay S, Arasteh M, Lawley TD, Dougan G, Bassett A, Karlsen TH, Kaser A, Kaneider NC (2019)
    GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump
    Sci Signal, 12 (562)
    DOI 10.1126/scisignal.aau9048, PubMed 30600262
24. Storm-Larsen C, Myhr KM, Farbu E, Midgard R, Nyquist K, Broch L, Berg-Hansen P, Buness A, Holm K, Ueland T, Fallang LE, Burum-Auensen E, Hov JR, Holmøy T (2019)
    Gut microbiota composition during a 12-week intervention with delayed-release dimethyl fumarate in multiple sclerosis - a pilot trial
    Mult Scler J Exp Transl Clin, 5 (4), 2055217319888767
    DOI 10.1177/2055217319888767, PubMed 31798939
25. Syse VL, Brekke M, Grimsrud MM, Persett PS, Heyerdahl F, Hovda KE, Vallersnes OM (2019)
    Gender differences in acute recreational drug toxicity: a case series from Oslo, Norway
    BMC Emerg Med, 19 (1), 29
    DOI 10.1186/s12873-019-0244-3, PubMed 31035940
26. Thingholm LB, Rühlemann MC, Koch M, Fuqua B, Laucke G, Boehm R, Bang C, Franzosa EA, Hübenthal M, Rahnavard A, Frost F, Lloyd-Price J, Schirmer M, Lusis AJ, Vulpe CD, Lerch MM, Homuth G, Kacprowski T, Schmidt CO, Nöthlings U, Karlsen TH, Lieb W, Laudes M, Franke A, Huttenhower C (2019)
    Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition
    Cell Host Microbe, 26 (2), 252-264.e10
    DOI 10.1016/j.chom.2019.07.004, PubMed 31399369
27. Trøseid M, Mayerhofer CCK, Broch K, Arora S, Svardal A, Hov JR, Andreassen AK, Gude E, Karason K, Dellgren G, Berge RK, Gullestad L, Aukrust P, Ueland T (2019)
    The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection
    J Heart Lung Transplant, 38 (10), 1097-1103
    DOI 10.1016/j.healun.2019.06.003, PubMed 31301965
28. Tysoe OC, Justin AW, Brevini T, Chen SE, Mahbubani KT, Frank AK, Zedira H, Melum E, Saeb-Parsy K, Markaki AE, Vallier L, Sampaziotis F (2019)
    Isolation and propagation of primary human cholangiocyte organoids for the generation of bioengineered biliary tissue
    Nat Protoc, 14 (6), 1884-1925
    DOI 10.1038/s41596-019-0168-0, PubMed 31110298

Publications 2018

1. Arnbjerg CJ, Vestad B, Hov JR, Pedersen KK, Jespersen S, Johannesen HH, Holm K, Halvorsen B, Fallentin E, Hansen AE, Lange T, Kjær A, Trøseid M, Fischer BM, Nielsen SD (2018)
   Effect of Lactobacillus rhamnosus GG Supplementation on Intestinal Inflammation Assessed by PET/MRI Scans and Gut Microbiota Composition in HIV-Infected Individuals
   J Acquir Immune Defic Syndr, 78 (4), 450-457
   DOI 10.1097/QAI.0000000000001693, PubMed 29874201
2. Berntsen NL, Fosby B, Tan C, Reims HM, Ogaard J, Jiang X, Schrumpf E, Valestrand L, Karlsen TH, Line PD, Blumberg RS, Melum E (2018)
   Natural killer T cells mediate inflammation in the bile ducts
   Mucosal Immunol, 11 (6), 1582-1590
   DOI 10.1038/s41385-018-0066-8, PubMed 30115993
3. Broce I, Karch CM, Wen N, Fan CC, Wang Y, Tan CH, Kouri N, Ross OA, Höglinger GU, Muller U, Hardy J, International FTD-Genomics Consortium, Momeni P, Hess CP, Dillon WP, Miller ZA, Bonham LW, Rabinovici GD, Rosen HJ, Schellenberg GD, Franke A, Karlsen TH, Veldink JH, Ferrari R, Yokoyama JS et al. (2018)
   Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
   PLoS Med, 15 (1), e1002487
   DOI 10.1371/journal.pmed.1002487, PubMed 29315334
4. Chung BK, Henriksen EKK, Jørgensen KK, Karlsen TH, Hirschfield GM, Liaskou E (2018)
   Gut and Liver B Cells of Common Clonal Origin in Primary Sclerosing Cholangitis-Inflammatory Bowel Disease
   Hepatol Commun, 2 (8), 956-967
   DOI 10.1002/hep4.1200, PubMed 30094406
5. Colombo M, Karlsen TH (2018)
   The EASL International Liver Foundation: A growing pup with missions that are distinct yet integrated with those of its mother
   J Hepatol, 70 (3), 339-342
   DOI 10.1016/j.jhep.2018.11.017, PubMed 30577976
6. Dhillon AK, Kummen M, Trøseid M, Åkra S, Liaskou E, Moum B, Vesterhus M, Karlsen TH, Seljeflot I, Hov JR (2018)
   Circulating markers of gut barrier function associated with disease severity in primary sclerosing cholangitis
   Liver Int, 39 (2), 371-381
   DOI 10.1111/liv.13979, PubMed 30269440
7. Eaton JE, Vesterhus M, McCauley BM, Atkinson EJ, Schlicht EM, Juran BD, Gossard AA, LaRusso NF, Gores GJ, Karlsen TH, Lazaridis KN (2018)
   Primary Sclerosing Cholangitis Risk Estimate Tool (PREsTo) Predicts Outcomes of the Disease: A Derivation and Validation Study Using Machine Learning
   Hepatology, 71 (1), 214-224
   DOI 10.1002/hep.30085, PubMed 29742811
8. Hoel H, Hove-Skovsgaard M, Hov JR, Gaardbo JC, Holm K, Kummen M, Rudi K, Nwosu F, Valeur J, Gelpi M, Seljeflot I, Ueland PM, Gerstoft J, Ullum H, Aukrust P, Nielsen SD, Trøseid M (2018)
   Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction
   Sci Rep, 8 (1), 6725
   DOI 10.1038/s41598-018-25168-3, PubMed 29712976
9. Holmer M, Melum E, Isoniemi H, Ericzon BG, Castedal M, Nordin A, Aagaard Schultz N, Rasmussen A, Line PD, Stål P, Bennet W, Hagström H (2018)
   Nonalcoholic fatty liver disease is an increasing indication for liver transplantation in the Nordic countries
   Liver Int, 38 (11), 2082-2090
   DOI 10.1111/liv.13751, PubMed 29630771
10. Karlsen TH, Tacke F (2018)
    «The times they are a'changin'» - Positioning the European Association for the Study of the Liver in the changing landscape of hepatology
    J Hepatol, 68 (5), 873-875
    DOI 10.1016/j.jhep.2018.02.001, PubMed 29500035
11. Kummen M, Mayerhofer CCK, Vestad B, Broch K, Awoyemi A, Storm-Larsen C, Ueland T, Yndestad A, Hov JR, Trøseid M (2018)
    Gut Microbiota Signature in Heart Failure Defined From Profiling of 2 Independent Cohorts
    J Am Coll Cardiol, 71 (10), 1184-1186
    DOI 10.1016/j.jacc.2017.12.057, PubMed 29519360
12. Lindström L, Jørgensen KK, Boberg KM, Castedal M, Rasmussen A, Rostved AA, Isoniemi H, Bottai M, Bergquist A (2018)
    Risk factors and prognosis for recurrent primary sclerosing cholangitis after liver transplantation: a Nordic Multicentre Study
    Scand J Gastroenterol, 53 (3), 297-304
    DOI 10.1080/00365521.2017.1421705, PubMed 29301479
13. Mazzawi T, Lied GA, Sangnes DA, El-Salhy M, Hov JR, Gilja OH, Hatlebakk JG, Hausken T (2018)
    The kinetics of gut microbial community composition in patients with irritable bowel syndrome following fecal microbiota transplantation
    PLoS One, 13 (11), e0194904
    DOI 10.1371/journal.pone.0194904, PubMed 30427836
14. Momozawa Y, Dmitrieva J, Théâtre E, Deffontaine V, Rahmouni S, Charloteaux B, Crins F, Docampo E, Elansary M, Gori AS, Lecut C, Mariman R, Mni M, Oury C, Altukhov I, Alexeev D, Aulchenko Y, Amininejad L, Bouma G, Hoentjen F, Löwenberg M, Oldenburg B, Pierik MJ, Vander Meulen-de Jong AE, Janneke van der Woude C et al. (2018)
    IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
    Nat Commun, 9 (1), 2427
    DOI 10.1038/s41467-018-04365-8, PubMed 29930244
15. Mulabecirovic A, Mjelle AB, Gilja OH, Vesterhus M, Havre RF (2018)
    Repeatability of shear wave elastography in liver fibrosis phantoms-Evaluation of five different systems
    PLoS One, 13 (1), e0189671
    DOI 10.1371/journal.pone.0189671, PubMed 29293527
16. Mulabecirovic A, Mjelle AB, Gilja OH, Vesterhus M, Havre RF (2018)
    Liver elasticity in healthy individuals by two novel shear-wave elastography systems-Comparison by age, gender, BMI and number of measurements
    PLoS One, 13 (9), e0203486
    DOI 10.1371/journal.pone.0203486, PubMed 30216377
17. Paquin-Proulx D, Greenspun BC, Pasquet L, Strunz B, Aleman S, Falconer K, Terabe M, Berzofsky JA, Sandberg JK, Melum E, Nixon DF, Björkström NK (2018)
    IL13Rα2 expression identifies tissue-resident IL-22-producing PLZF⁺ innate T cells in the human liver
    Eur J Immunol, 48 (8), 1329-1335
    DOI 10.1002/eji.201747334, PubMed 29677387
18. Pihlstrøm HK, Mjøen G, Mucha S, Franke A, Jardine A, Fellström B, Dahle DO, Holdaas H, Melum E (2018)
    Genetic markers associated with long-term cardiovascular outcome in kidney transplant recipients
    Am J Transplant, 19 (5), 1444-1451
    DOI 10.1111/ajt.15191, PubMed 30457209
19. Pollheimer MJ, Racedo S, Mikels-Vigdal A, Marshall D, Bowlus C, Lackner C, Madl T, Karlsen TH, Hov JR, Lyman SK, Adamkewicz J, Smith V, Moreau E, Zollner G, Eide TJ, Stojakovic T, Scharnagl H, Gruber HJ, Stauber RE, Trauner M, Fickert P (2018)
    Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis
    J Hepatol, 69 (2), 368-377
    DOI 10.1016/j.jhep.2018.04.009, PubMed 29709678
20. Schmitt C, Lenglet H, Yu A, Delaby C, Benecke A, Lefebvre T, Letteron P, Paradis V, Wahlin S, Sandberg S, Harper P, Sardh E, Sandvik AK, Hov JR, Aarsand AK, Chiche L, Bazille C, Scoazec JY, To-Figueras J, Carrascal M, Abian J, Mirmiran A, Karim Z, Deybach JC, Puy H et al. (2018)
    Recurrent attacks of acute hepatic porphyria: major role of the chronic inflammatory response in the liver
    J Intern Med, 284 (1), 78-91
    DOI 10.1111/joim.12750, PubMed 29498764
21. Schrumpf E, Rizvi SMH (2018)
    Pustular drug rash
    Tidsskr. Nor. Laegeforen., 138 (18), 1746
22. Thorgersen EB, Melum E, Folseraas T, Larsen SG, Line PD (2018)
    Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei in a liver-transplanted patient: a case report
    World J Surg Oncol, 16 (1), 180
    DOI 10.1186/s12957-018-1482-7, PubMed 30185175
23. Tronstad RR, Polushina T, Brattbakk HR, Stansberg C, von Volkmann HL, Hanevik K, Ellinghaus E, Jørgensen SF, Ersland KM, Pham KD, Gilja OH, Hovdenak N, Hausken T, Vatn MH, Franke A, Knappskog PM, Le Hellard S, Karlsen TH, Fiskerstrand T (2018)
    Genetic and transcriptional analysis of inflammatory bowel disease-associated pathways in patients with GUCY2C-linked familial diarrhea
    Scand J Gastroenterol, 53 (10-11), 1264-1273
    DOI 10.1080/00365521.2018.1521867, PubMed 30353760
24. Åberg F, Isoniemi H, Pukkala E, Jalanko H, Rasmussen A, Storm HH, Schultz N, Bennet W, Ekvall N, Ericzon BG, Malenicka S, Tretli S, Line PD, Boberg KM, Østensen A, Karlsen TH, Nordin A (2018)
    Cancer After Liver Transplantation in Children and Young Adults: A Population-Based Study From 4 Nordic Countries
    Liver Transpl, 24 (9), 1252-1259
    DOI 10.1002/lt.25305, PubMed 30120902

Publications 2017

1. Alberts R, de Vries EMG, Goode EC, Jiang X, Sampaziotis F, Rombouts K, Böttcher K, Folseraas T, Weismüller TJ, Mason AL, Wang W, Alexander G, Alvaro D, Bergquist A, Björkström NK, Beuers U, Björnsson E, Boberg KM, Bowlus CL, Bragazzi MC, Carbone M, Chazouillères O, Cheung A, Dalekos G, Eaton J et al. (2017)
   Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis
   Gut, 67 (8), 1517-1524
   DOI 10.1136/gutjnl-2016-313598, PubMed 28779025
2. Bende F, Mulabecirovic A, Sporea I, Popescu A, Sirli R, Gilja OH, Vesterhus M, Havre RF (2017)
   Assessing Liver Stiffness by 2-D Shear Wave Elastography in a Healthy Cohort
   Ultrasound Med Biol, 44 (2), 332-341
   DOI 10.1016/j.ultrasmedbio.2017.10.013, PubMed 29249457
3. Berntsen NL, Fosby B, Valestrand L, Tan C, Reims HM, Schrumpf E, Karlsen TH, Line PD, Melum E (2017)
   Establishment of a surgical bile duct injection technique giving direct access to the bile ducts for studies of the murine biliary tree
   Am J Physiol Gastrointest Liver Physiol, 314 (3), G349-G359
   DOI 10.1152/ajpgi.00124.2017, PubMed 29212771
4. Carpino G, Cardinale V, Folseraas T, Overi D, Floreani A, Franchitto A, Onori P, Cazzagon N, Berloco PB, Karlsen TH, Alvaro D, Gaudio E (2017)
   Hepatic Stem/Progenitor Cell Activation Differs between Primary Sclerosing and Primary Biliary Cholangitis
   Am J Pathol, 188 (3), 627-639
   DOI 10.1016/j.ajpath.2017.11.010, PubMed 29248458
5. Chung BK, Hirschfield GM (2017)
   Immunogenetics in primary sclerosing cholangitis
   Curr Opin Gastroenterol, 33 (2), 93-98
   DOI 10.1097/MOG.0000000000000336, PubMed 28146446
6. Chung BK, Karlsen TH (2017)
   Genetic Discoveries Highlight Environmental Factors as Key Drivers of Liver Disease
   Dig Dis, 35 (4), 323-333
   DOI 10.1159/000456583, PubMed 28468012
7. Chung BK, Karlsen TH, Folseraas T (2017)
   Cholangiocytes in the pathogenesis of primary sclerosing cholangitis and development of cholangiocarcinoma
   Biochim Biophys Acta Mol Basis Dis, 1864 (4 Pt B), 1390-1400
   DOI 10.1016/j.bbadis.2017.08.020, PubMed 28844951
8. Claussen JC, Skiecevičienė J, Wang J, Rausch P, Karlsen TH, Lieb W, Baines JF, Franke A, Hütt MT (2017)
   Boolean analysis reveals systematic interactions among low-abundance species in the human gut microbiome
   PLoS Comput Biol, 13 (6), e1005361
   DOI 10.1371/journal.pcbi.1005361, PubMed 28640804
9. de Muinck EJ, Trosvik P, Gilfillan GD, Hov JR, Sundaram AYM (2017)
   A novel ultra high-throughput 16S rRNA gene amplicon sequencing library preparation method for the Illumina HiSeq platform
   Microbiome, 5 (1), 68
   DOI 10.1186/s40168-017-0279-1, PubMed 28683838
10. de Vries EMG, Färkkilä M, Milkiewicz P, Hov JR, Eksteen B, Thorburn D, Chazouillères O, Pares A, Nygård S, Gilja OH, Wunsch E, Invernizzi P, Carbone M, Bernuzzi F, Boberg KM, Røsjø H, Rosenberg W, Beuers UH, Ponsioen CY, Karlsen TH, Vesterhus M (2017)
    Enhanced liver fibrosis test predicts transplant-free survival in primary sclerosing cholangitis, a multi-centre study
    Liver Int, 37 (10), 1554-1561
    DOI 10.1111/liv.13402, PubMed 28267887
11. Haissman JM, Haugaard AK, Ostrowski SR, Berge RK, Hov JR, Trøseid M, Nielsen SD (2017)
    Microbiota-dependent metabolite and cardiovascular disease marker trimethylamine-N-oxide (TMAO) is associated with monocyte activation but not platelet function in untreated HIV infection
    BMC Infect Dis, 17 (1), 445
    DOI 10.1186/s12879-017-2547-x, PubMed 28645263
12. Henriksen EKK, Viken MK, Wittig M, Holm K, Folseraas T, Mucha S, Melum E, Hov JR, Lazaridis KN, Juran BD, Chazouillères O, Färkkilä M, Gotthardt DN, Invernizzi P, Carbone M, Hirschfield GM, Rushbrook SM, Goode E, UK-PSC Consortium, Ponsioen CY, Weersma RK, Eksteen B, Yimam KK, Gordon SC, Goldberg D et al. (2017)
    HLA haplotypes in primary sclerosing cholangitis patients of admixed and non-European ancestry
    HLA, 90 (4), 228-233
    DOI 10.1111/tan.13076, PubMed 28695657
13. Hov JR, Karlsen TH (2017)
    The Microbiome in Primary Sclerosing Cholangitis: Current Evidence and Potential Concepts
    Semin Liver Dis, 37 (4), 314-331
    DOI 10.1055/s-0037-1608801, PubMed 29272894
14. Hov JR, Kummen M (2017)
    Intestinal microbiota in primary sclerosing cholangitis
    Curr Opin Gastroenterol, 33 (2), 85-92
    DOI 10.1097/MOG.0000000000000334, PubMed 28030369
15. Jahnsen FL, Bækkevold ES, Hov JR, Landsverk OJ (2017)
    Do Long-Lived Plasma Cells Maintain a Healthy Microbiota in the Gut?
    Trends Immunol, 39 (3), 196-208
    DOI 10.1016/j.it.2017.10.006, PubMed 29162322
16. Jahnsen J, Kaasen Jørgensen K (2017)
    Experience with Biosimilar Infliximab (Remsima®) in Norway
    Dig Dis, 35 (1-2), 83-90
    DOI 10.1159/000449088, PubMed 28147374
17. Jiang X, Björkström NK, Melum E (2017)
    Intact CD100-CD72 Interaction Necessary for TCR-Induced T Cell Proliferation
    Front Immunol, 8, 765
    DOI 10.3389/fimmu.2017.00765, PubMed 28713384
18. Jiang X, Karlsen TH (2017)
    Genetics of primary sclerosing cholangitis and pathophysiological implications
    Nat Rev Gastroenterol Hepatol, 14 (5), 279-295
    DOI 10.1038/nrgastro.2016.154, PubMed 28293027
19. Karlsen TH, Folseraas T, Thorburn D, Vesterhus M (2017)
    Primary sclerosing cholangitis - a comprehensive review
    J Hepatol, 67 (6), 1298-1323
    DOI 10.1016/j.jhep.2017.07.022, PubMed 28802875
20. Koch M, Freitag-Wolf S, Schlesinger S, Borggrefe J, Hov JR, Jensen MK, Pick J, Markus MRP, Höpfner T, Jacobs G, Siegert S, Artati A, Kastenmüller G, Römisch-Margl W, Adamski J, Illig T, Nothnagel M, Karlsen TH, Schreiber S, Franke A, Krawczak M, Nöthlings U, Lieb W (2017)
    Serum metabolomic profiling highlights pathways associated with liver fat content in a general population sample
    Eur J Clin Nutr, 71 (8), 995-1001
    DOI 10.1038/ejcn.2017.43, PubMed 28378853
21. Landskron J, Kraggerud SM, Wik E, Dørum A, Bjørnslett M, Melum E, Helland Ø, Bjørge L, Lothe RA, Salvesen HB, Taskén K (2017)
    C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease
    PLoS One, 12 (7), e0182030
    DOI 10.1371/journal.pone.0182030, PubMed 28759630
22. Lunder AK, Jahnsen J, Bakstad LT, Borthne A, Hov JR, Vatn M, Negård A, IBSEN Study Group (2017)
    Bowel Damage in Patients With Long-term Crohn's Disease, Assessed by Magnetic Resonance Enterography and the Lémann Index
    Clin Gastroenterol Hepatol, 16 (1), 75-82.e5
    DOI 10.1016/j.cgh.2017.06.053, PubMed 28694130
23. Maroni L, Hohenester SD, van de Graaf SFJ, Tolenaars D, van Lienden K, Verheij J, Marzioni M, Karlsen TH, Oude Elferink RPJ, Beuers U (2017)
    Knockout of the primary sclerosing cholangitis-risk gene Fut2 causes liver disease in mice
    Hepatology, 66 (2), 542-554
    DOI 10.1002/hep.29029, PubMed 28056490
24. Mayerhofer CCK, Ueland T, Broch K, Vincent RP, Cross GF, Dahl CP, Aukrust P, Gullestad L, Hov JR, Trøseid M (2017)
    Increased Secondary/Primary Bile Acid Ratio in Chronic Heart Failure
    J Card Fail, 23 (9), 666-671
    DOI 10.1016/j.cardfail.2017.06.007, PubMed 28688889
25. Meijerink H, White RA, Løvlie A, de Blasio BF, Dalgard O, Amundsen EJ, Melum E, Kløvstad H (2017)
    Modelling the burden of hepatitis C infection among people who inject drugs in Norway, 1973-2030
    BMC Infect Dis, 17 (1), 541
    DOI 10.1186/s12879-017-2631-2, PubMed 28774261
26. Nordin A, Åberg F, Pukkala E, Pedersen CR, Storm HH, Rasmussen A, Bennet W, Olausson M, Wilczek H, Ericzon BG, Tretli S, Line PD, Karlsen TH, Boberg KM, Isoniemi H (2017)
    Decreasing incidence of cancer after liver transplantation-A Nordic population-based study over 3 decades
    Am J Transplant, 18 (4), 952-963
    DOI 10.1111/ajt.14507, PubMed 28925583
27. O'Hara SP, Karlsen TH, LaRusso NF (2017)
    Cholangiocytes and the environment in primary sclerosing cholangitis: where is the link?
    Gut, 66 (11), 1873-1877
    DOI 10.1136/gutjnl-2017-314249, PubMed 28733279
28. Rosati E, Dowds CM, Liaskou E, Henriksen EKK, Karlsen TH, Franke A (2017)
    Overview of methodologies for T-cell receptor repertoire analysis
    BMC Biotechnol, 17 (1), 61
    DOI 10.1186/s12896-017-0379-9, PubMed 28693542
29. Rühlemann MC, Degenhardt F, Thingholm LB, Wang J, Skiecevičienė J, Rausch P, Hov JR, Lieb W, Karlsen TH, Laudes M, Baines JF, Heinsen FA, Franke A (2017)
    Application of the distance-based F test in an mGWAS investigating β diversity of intestinal microbiota identifies variants in SLC9A8 (NHE8) and 3 other loci
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