Sissel Åkra

  • Dept. Engineer, Biobank; MSc
 

Publications 2024

Aune SK, Helseth R, Kalstad AA, Laake K, Åkra S, Arnesen H, Solheim S, Seljeflot I (2024)
Links Between Adipose Tissue Gene Expression of Gut Leakage Markers, Circulating Levels, Anthropometrics, and Diet in Patients with Coronary Artery Disease
Diabetes Metab Syndr Obes, 17, 2177-2190
DOI 10.2147/DMSO.S438818, PubMed 38827167

Kindberg KM, Broch K, Andersen GØ, Anstensrud AK, Åkra S, Woxholt S, Tøllefsen IM, Ueland T, Amundsen BH, Kløw NE, Halvorsen B, Dahl TB, Huse C, Murphy SL, Damås JK, Opdahl A, Wiseth R, Gullestad L, Aukrust P, Santos-Gallego C, Seljeflot I, Stokke MK, Helseth R (2024)
Neutrophil Extracellular Traps in ST-Segment Elevation Myocardial Infarction: Reduced by Tocilizumab and Associated With Infarct Size
JACC Adv, 3 (9), 101193
DOI 10.1016/j.jacadv.2024.101193, PubMed 39247678

Publications 2023

Opstad TB, Papotti B, Åkra S, Hansen CH, Braathen B, Tønnessen T, Solheim S, Seljeflot I (2023)
Sirtuin1, not NAMPT, possesses anti-inflammatory effects in epicardial, pericardial and subcutaneous adipose tissue in patients with CHD
J Transl Med, 21 (1), 644
DOI 10.1186/s12967-023-04518-4, PubMed 37730614

Papotti B, Opstad TB, Åkra S, Tønnessen T, Braathen B, Hansen CH, Arnesen H, Solheim S, Seljeflot I, Ronda N (2023)
Macrophage polarization markers in subcutaneous, pericardial, and epicardial adipose tissue are altered in patients with coronary heart disease
Front Cardiovasc Med, 10, 1055069
DOI 10.3389/fcvm.2023.1055069, PubMed 36937936

Publications 2022

Bratseth V, Nordeng J, Helseth R, Solheim S, Åkra S, Arnesen H, Chiva-Blanch G, Seljeflot I (2022)
Circulating Microvesicles in Association with the NLRP3 Inflammasome in Coronary Thrombi from STEMI Patients
Biomedicines, 10 (9)
DOI 10.3390/biomedicines10092196, PubMed 36140297

Nordeng J, Schandiz H, Solheim S, Åkra S, Hoffman P, Roald B, Bendz B, Arnesen H, Helseth R, Seljeflot I (2022)
TIMP-1 expression in coronary thrombi associate with myocardial injury in ST-elevation myocardial infarction patients
Coron Artery Dis, 33 (6), 446-455
DOI 10.1097/MCA.0000000000001128, PubMed 35102064

Nordeng J, Solheim S, Åkra S, Schandiz H, Hoffmann P, Roald B, Bendz B, Arnesen H, Helseth R, Seljeflot I (2022)
Gene expression of fibrinolytic markers in coronary thrombi
Thromb J, 20 (1), 23
DOI 10.1186/s12959-022-00383-1, PubMed 35488283

Opstad TB, Nordeng J, Pettersen AR, Åkra S, Bratseth V, Zaidi H, Helseth R, Solheim S, Seljeflot I (2022)
The NLRP3 Genetic Variant (rs10754555) Reduces the Risk of Adverse Outcome in Middle-Aged Patients with Chronic Coronary Syndrome
J Immunol Res, 2022, 2366695
DOI 10.1155/2022/2366695, PubMed 36582742

Zaidi H, Aksnes T, Åkra S, Eggesbø HB, Byrkjeland R, Seljeflot I, Opstad TB (2022)
Abdominal Adipose Tissue Associates With Adiponectin and TNFα in Middle-Aged Healthy Men
Front Endocrinol (Lausanne), 13, 874977
DOI 10.3389/fendo.2022.874977, PubMed 35872989

Åkra S, Seljeflot I, Braathen B, Bratseth V, Hansen CH, Arnesen H, Tønnessen T, Solheim S (2022)
The NLRP3 inflammasome activation in subcutaneous, epicardial and pericardial adipose tissue in patients with coronary heart disease undergoing coronary by-pass surgery
Atheroscler Plus, 48, 47-54
DOI 10.1016/j.athplu.2022.03.005, PubMed 36644557

Publications 2021

Awoyemi A, Mayerhofer C, Felix AS, Hov JR, Moscavitch SD, Lappegård KT, Hovland A, Halvorsen S, Halvorsen B, Gregersen I, Svardal A, Berge RK, Hansen SH, Götz A, Holm K, Aukrust P, Åkra S, Seljeflot I, Solheim S, Lorenzo A, Gullestad L, Trøseid M, Broch K (2021)
Rifaximin or Saccharomyces boulardii in heart failure with reduced ejection fraction: Results from the randomized GutHeart trial
EBioMedicine, 70, 103511
DOI 10.1016/j.ebiom.2021.103511, PubMed 34329947

Nordeng J, Schandiz H, Solheim S, Åkra S, Hoffman P, Roald B, Bendz B, Arnesen H, Helseth R, Seljeflot I (2021)
The Inflammasome Signaling Pathway Is Actively Regulated and Related to Myocardial Damage in Coronary Thrombi from Patients with STEMI
Mediators Inflamm, 2021, 5525917
DOI 10.1155/2021/5525917, PubMed 34135690

Zaidi H, Byrkjeland R, Njerve IU, Åkra S, Solheim S, Arnesen H, Seljeflot I, Opstad TB (2021)
Adiponectin in relation to exercise and physical performance in patients with type 2 diabetes and coronary artery disease
Adipocyte, 10 (1), 612-620
DOI 10.1080/21623945.2021.1996699, PubMed 34779349

Publications 2020

Åkra S, Aksnes TA, Flaa A, Eggesbø HB, Opstad TB, Njerve IU, Seljeflot I (2020)
Markers of remodeling in subcutaneous adipose tissue are strongly associated with overweight and insulin sensitivity in healthy non-obese men
Sci Rep, 10 (1), 14055
DOI 10.1038/s41598-020-71109-4, PubMed 32820223

Publications 2019

Zaidi H, Byrkjeland R, Njerve IU, Åkra S, Solheim S, Arnesen H, Seljeflot I, Opstad TB (2019)
Effects of exercise training on inflammasome-related mediators and their associations to glucometabolic variables in patients with combined coronary artery disease and type 2 diabetes mellitus: Sub-study of a randomized control trial
Diab Vasc Dis Res, 16 (4), 360-368
DOI 10.1177/1479164119836922, PubMed 30939905

Zaidi H, Byrkjeland R, Njerve IU, Åkra S, Solheim S, Arnesen H, Seljeflot I, Opstad TB (2019)
Effects of exercise training on markers of adipose tissue remodeling in patients with coronary artery disease and type 2 diabetes mellitus: sub study of the randomized controlled EXCADI trial
Diabetol Metab Syndr, 11, 109
DOI 10.1186/s13098-019-0508-9, PubMed 31890043

Publications 2018

Dhillon AK, Kummen M, Trøseid M, Åkra S, Liaskou E, Moum B, Vesterhus M, Karlsen TH, Seljeflot I, Hov JR (2018)
Circulating markers of gut barrier function associated with disease severity in primary sclerosing cholangitis
Liver Int, 39 (2), 371-381
DOI 10.1111/liv.13979, PubMed 30269440

Åkra S, Aksnes TA, Flaa A, Eggesbø HB, Opstad TB, Njerve IU, Seljeflot I (2018)
Interleukin-18 and the NLR family pyrin domain containing-3 inflammasome in adipose tissue are strongly associated with glucometabolic variables in a cohort of middle-aged men
Diab Vasc Dis Res, 15 (5), 458-464
DOI 10.1177/1479164118785307, PubMed 29972041

Publications 2017

Njerve IU, Åkra S, Weiss TW, Solheim S, Øvstebø R, Aass HCD, Byrkjeland R, Arnesen H, Seljeflot I (2017)
A Double-Blinded Randomized Study Investigating a Possible Anti-Inflammatory Effect of Saxagliptin versus Placebo as Add-On Therapy in Patients with Both Type 2 Diabetes And Stable Coronary Artery Disease
Mediators Inflamm, 2017, 5380638
DOI 10.1155/2017/5380638, PubMed 28596642

Publications 2016

Njerve IU, Byrkjeland R, Arnesen H, Åkra S, Solheim S, Seljeflot I (2016)
Effects of long-term exercise training on adipose tissue expression of fractalkine and MCP-1 in patients with type 2 diabetes and stable coronary artery disease: a substudy of a randomized controlled trial
Diabetes Metab Syndr Obes, 9, 55-62
DOI 10.2147/DMSO.S96299, PubMed 27042130

Publications 2011

Opstad TB, Pettersen AA, Weiss TW, Akra S, Øvstebø R, Arnesen H, Seljeflot I (2011)
Genetic variation, gene-expression and circulating levels of matrix metalloproteinase-9 in patients with stable coronary artery disease
Clin Chim Acta, 413 (1-2), 113-20
DOI 10.1016/j.cca.2011.09.004, PubMed 21963461