Publications

Publications published since 2006 from OUS - Department of Molecular Oncology (2006-2014 Dept of Cancer Prev.)

350 publications found

Publications 2024

1. Grindedal EM, Zucknick M, Stormorken A, Rønne E, Tandstad NM, Isaacs WB, Axcrona K, Mæhle L (2024)
   Outcomes of 10 years of PSA screening for prostate cancer in Norwegian men with Lynch syndrome
   Prostate (in press)
   DOI 10.1002/pros.24711, PubMed 38629217
2. Majid U, Bergsland CH, Sveen A, Bruun J, Eilertsen IA, Bækkevold ES, Nesbakken A, Yaqub S, Jahnsen FL, Lothe RA (2024)
   The prognostic effect of tumor-associated macrophages in stage I-III colorectal cancer depends on T cell infiltration
   Cell Oncol (Dordr) (in press)
   DOI 10.1007/s13402-024-00926-w, PubMed 38407700
3. Skotheim RI, Bogaard M, Carm KT, Axcrona U, Axcrona K (2024)
   Prostate cancer: Molecular aspects, consequences, and opportunities of the multifocal nature
   Biochim Biophys Acta Rev Cancer, 1879 (2), 189080
   DOI 10.1016/j.bbcan.2024.189080, PubMed 38272101
4. Sveen A, Johannessen B, Klokkerud SM, Kraggerud SM, Meza-Zepeda LA, Bjørnslett M, Bischof K, Myklebost O, Taskén K, Skotheim RI, Dørum A, Davidson B, Lothe RA (2024)
   Evolutionary mode and timing of dissemination of high-grade serous carcinomas
   JCI Insight, 9 (3)
   DOI 10.1172/jci.insight.170423, PubMed 38175731
5. Totland MZ, Knudsen LM, Rasmussen NL, Omori Y, Sørensen V, Elster VCW, Stenersen JM, Larsen M, Jensen CL, Zickfeldt Lade AA, Bruusgaard E, Basing S, Kryeziu K, Brech A, Aasen T, Lothe RA, Leithe E (2024)
   The E3 ubiquitin ligase ITCH negatively regulates intercellular communication via gap junctions by targeting connexin43 for lysosomal degradation
   Cell Mol Life Sci, 81 (1), 171
   DOI 10.1007/s00018-024-05165-8, PubMed 38597989

Publications 2023

1. Bogaard M, Skotheim RI, Maltau AV, Kidd SG, Lothe RA, Axcrona K, Axcrona U (2023)
   'High proliferative cribriform prostate cancer' defines a patient subgroup with an inferior prognosis
   Histopathology, 83 (6), 853-869
   DOI 10.1111/his.15012, PubMed 37501635
2. Høland M, Berg KCG, Eilertsen IA, Bjerkehagen B, Kolberg M, Boye K, Lingjærde OC, Guren TK, Mandahl N, van den Berg E, Palmerini E, Smeland S, Picci P, Mertens F, Sveen A, Lothe RA (2023)
   Transcriptomic subtyping of malignant peripheral nerve sheath tumours highlights immune signatures, genomic profiles, patient survival and therapeutic targets
   EBioMedicine, 97, 104829
   DOI 10.1016/j.ebiom.2023.104829, PubMed 37837931
3. Jeanmougin M, Brodal HP, Dietrichson Pharo H, Vedeld HM, Lind GE (2023)
   PoDCall: positive droplet calling and normalization of droplet digital PCR DNA methylation data
   Bioinformatics, 39 (1)
   DOI 10.1093/bioinformatics/btac766, PubMed 36448696
4. Kresse SH, Brandt-Winge S, Pharo H, Flatin BTB, Jeanmougin M, Vedeld HM, Lind GE (2023)
   Evaluation of commercial kits for isolation and bisulfite conversion of circulating cell-free tumor DNA from blood
   Clin Epigenetics, 15 (1), 151
   DOI 10.1186/s13148-023-01563-0, PubMed 37710283
5. Meier Strømme J, Johannessen B, Skotheim RI (2023)
   Deviating Alternative Splicing as a Molecular Subtype of Microsatellite Stable Colorectal Cancer
   JCO Clin Cancer Inform, 7, e2200159
   DOI 10.1200/CCI.22.00159, PubMed 36821799
6. Totland MZ, Omori Y, Sørensen V, Kryeziu K, Aasen T, Brech A, Leithe E (2023)
   Endocytic trafficking of connexins in cancer pathogenesis
   Biochim Biophys Acta Mol Basis Dis, 1869 (7), 166812
   DOI 10.1016/j.bbadis.2023.166812, PubMed 37454772

Publications 2022

1. Axcrona K, Aas K, Axcrona U, Skotheim RI (2022)
   Re: Spatially Resolved Clonal Copy Number Alterations in Benign and Malignant Tissue
   Eur Urol, 83 (2), 183
   DOI 10.1016/j.eururo.2022.11.013, PubMed 36464529
2. Bergsland CH, Jeanmougin M, Moosavi SH, Svindland A, Bruun J, Nesbakken A, Sveen A, Lothe RA (2022)
   Spatial analysis and CD25-expression identify regulatory T cells as predictors of a poor prognosis in colorectal cancer
   Mod Pathol, 35 (9), 1236-1246
   DOI 10.1038/s41379-022-01086-8, PubMed 35484226
3. Carm KT, Johannessen B, Bogaard M, Bakken AC, Maltau AV, Hoff AM, Axcrona U, Axcrona K, Lothe RA, Skotheim RI (2022)
   Somatic mutations reveal complex metastatic seeding from multifocal primary prostate cancer
   Int J Cancer, 152 (5), 945-951
   DOI 10.1002/ijc.34226, PubMed 35880692
4. Fontugne J, Cai PY, Alnajar H, Bhinder B, Park K, Ye H, Beg S, Sailer V, Siddiqui J, Blattner-Johnson M, Croyle JA, Noorzad Z, Calagua C, MacDonald TY, Axcrona U, Bogaard M, Axcrona K, Scherr DS, Sanda MG, Johannessen B, Chinnaiyan AM, Elemento O, Skotheim RI, Rubin MA, Barbieri CE et al. (2022)
   Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci
   JCI Insight, 7 (4)
   DOI 10.1172/jci.insight.155309, PubMed 35050902
5. Grasso C, Popovic M, Isaevska E, Lazzarato F, Fiano V, Zugna D, Pluta J, Weathers B, D'Andrea K, Almstrup K, Anson-Cartwright L, Bishop DT, Chanock SJ, Chen C, Cortessis VK, Dalgaard MD, Daneshmand S, Ferlin A, Foresta C, Frone MN, Gamulin M, Gietema JA, Greene MH, Grotmol T, Hamilton RJ et al. (2022)
   Association Study between Polymorphisms in DNA Methylation-Related Genes and Testicular Germ Cell Tumor Risk
   Cancer Epidemiol Biomarkers Prev, 31 (9), 1769-1779
   DOI 10.1158/1055-9965.EPI-22-0123, PubMed 35700037
6. Helland Å, Russnes HG, Fagereng GL, Al-Shibli K, Andersson Y, Berg T, Bjørge L, Blix E, Bjerkehagen B, Brabrand S, Cameron MG, Dalhaug A, Dietzel D, Dønnem T, Enerly E, Flobak Å, Fluge S, Gilje B, Gjertsen BT, Grønberg BH, Grønås K, Guren T, Hamre H, Haug Å, Heinrich D et al. (2022)
   Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
   J Transl Med, 20 (1), 225
   DOI 10.1186/s12967-022-03432-5, PubMed 35568909
7. Helland Å, Russnes HG, Fagereng GL, Al-Shibli K, Andersson Y, Berg T, Bjørge L, Blix E, Bjerkehagen B, Brabrand S, Cameron MG, Dalhaug A, Dietzel D, Dønnem T, Enerly E, Flobak Å, Fluge S, Gilje B, Gjertsen BT, Grønberg BH, Grønås K, Guren T, Hamre H, Haug Å, Heinrich D et al. (2022)
   Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
   J Transl Med, 20 (1), 317
   DOI 10.1186/s12967-022-03518-0, PubMed 35841045
8. Hugosson J, Månsson M, Wallström J, Axcrona U, Carlsson SV, Egevad L, Geterud K, Khatami A, Kohestani K, Pihl CG, Socratous A, Stranne J, Godtman RA, Hellström M, GÖTEBORG-2 Trial Investigators (2022)
   Prostate Cancer Screening with PSA and MRI Followed by Targeted Biopsy Only
   N Engl J Med, 387 (23), 2126-2137
   DOI 10.1056/NEJMoa2209454, PubMed 36477032
9. Kidd SG, Bogaard M, Carm KT, Bakken AC, Maltau AMV, Løvf M, Lothe RA, Axcrona K, Axcrona U, Skotheim RI (2022)
   In situ expression of ERG protein in the context of tumor heterogeneity identifies prostate cancer patients with inferior prognosis
   Mol Oncol, 16 (15), 2810-2822
   DOI 10.1002/1878-0261.13225, PubMed 35574900
10. Kryeziu K, Bergsland CH, Guren TK, Sveen A, Lothe RA (2022)
    Multiplex immunohistochemistry of metastatic colorectal cancer and ex vivo tumor avatars
    Biochim Biophys Acta Rev Cancer, 1877 (1), 188682
    DOI 10.1016/j.bbcan.2022.188682, PubMed 35065193
11. Namløs HM, Skårn M, Ahmed D, Grad I, Andresen K, Kresse SH, Munthe E, Serra M, Scotlandi K, Llombart-Bosch A, Myklebost O, Lind GE, Meza-Zepeda LA (2022)
    miR-486-5p expression is regulated by DNA methylation in osteosarcoma
    BMC Genomics, 23 (1), 142
    DOI 10.1186/s12864-022-08346-6, PubMed 35172717
12. Pharo HD, Jeanmougin M, Ager-Wick E, Vedeld HM, Sørbø AK, Dahl C, Larsen LK, Honne H, Brandt-Winge S, Five MB, Monteiro-Reis S, Henrique R, Jeronimo C, Steven K, Wahlqvist R, Guldberg P, Lind GE (2022)
    BladMetrix: a novel urine DNA methylation test with high accuracy for detection of bladder cancer in hematuria patients
    Clin Epigenetics, 14 (1), 115
    DOI 10.1186/s13148-022-01335-2, PubMed 36115961
13. Pinto R, Hauge T, Jeanmougin M, Pharo HD, Kresse SH, Honne H, Winge SB, Five MB, Kumar T, Mala T, Hauge T, Johnson E, Lind GE (2022)
    Targeted genetic and epigenetic profiling of esophageal adenocarcinomas and non-dysplastic Barrett's esophagus
    Clin Epigenetics, 14 (1), 77
    DOI 10.1186/s13148-022-01287-7, PubMed 35701814
14. Skotheim RI, Axcrona U, Axcrona K (2022)
    Re: Fibroblast Growth Factor Receptor 1 Drives the Metastatic Progression of Prostate Cancer
    Eur Urol, 81 (4), 431
    DOI 10.1016/j.eururo.2021.12.031, PubMed 35031159
15. Strømme JM, Johannessen B, Kidd SG, Bogaard M, Carm KT, Zhang X, Sveen A, Mathelier A, Lothe RA, Axcrona U, Axcrona K, Skotheim RI (2022)
    Expressed prognostic biomarkers for primary prostate cancer independent of multifocality and transcriptome heterogeneity
    Cancer Gene Ther, 29 (8-9), 1276-1284
    DOI 10.1038/s41417-022-00444-7, PubMed 35194199
16. Wolowczyk C, Neckmann U, Aure MR, Hall M, Johannessen B, Zhao S, Skotheim RI, Andersen SB, Zwiggelaar R, Steigedal TS, Lingjærde OC, Sahlberg KK, Almaas E, Bjørkøy G (2022)
    NRF2 drives an oxidative stress response predictive of breast cancer
    Free Radic Biol Med, 184, 170-184
    DOI 10.1016/j.freeradbiomed.2022.03.029, PubMed 35381325

Publications 2021

1. Aranguren-Abadía L, Yadetie F, Donald CE, Sørhus E, Myklatun LE, Zhang X, Lie KK, Perrichon P, Nakken CL, Durif C, Shema S, Browman HI, Skiftesvik AB, Goksøyr A, Meier S, Karlsen OA (2021)
   Photo-enhanced toxicity of crude oil on early developmental stages of Atlantic cod (Gadus morhua)
   Sci Total Environ, 807 (Pt 1), 150697
   DOI 10.1016/j.scitotenv.2021.150697, PubMed 34610396
2. Berg KCG, Brunsell TH, Sveen A, Alagaratnam S, Bjørnslett M, Hektoen M, Brudvik KW, Røsok BI, Bjørnbeth BA, Nesbakken A, Lothe RA (2021)
   Genomic and prognostic heterogeneity among RAS/BRAF^V600E /TP53 co-mutated resectable colorectal liver metastases
   Mol Oncol, 15 (4), 830-845
   DOI 10.1002/1878-0261.12885, PubMed 33325154
3. Bruun J, Eide PW, Bergsland CH, Bruck O, Svindland A, Arjama M, Välimäki K, Bjørnslett M, Guren MG, Kallioniemi O, Nesbakken A, Lothe RA, Pellinen T (2021)
   E-cadherin is a robust prognostic biomarker in colorectal cancer and low expression is associated with sensitivity to inhibitors of topoisomerase, aurora, and HSP90 in preclinical models
   Mol Oncol, 16 (12), 2312-2329
   DOI 10.1002/1878-0261.13159, PubMed 34890102
4. Dale K, Yadetie F, Horvli T, Zhang X, Frøysa HG, Karlsen OA, Goksøyr A (2021)
   Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua)
   Sci Total Environ, 814, 152732
   DOI 10.1016/j.scitotenv.2021.152732, PubMed 34974025
5. Davydova E, Shimazu T, Schuhmacher MK, Jakobsson ME, Willemen HLDM, Liu T, Moen A, Ho AYY, Małecki J, Schroer L, Pinto R, Suzuki T, Grønsberg IA, Sohtome Y, Akakabe M, Weirich S, Kikuchi M, Olsen JV, Dohmae N, Umehara T, Sodeoka M, Siino V, McDonough MA, Eijkelkamp N, Schofield CJ et al. (2021)
   The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes
   Nat Commun, 12 (1), 891
   DOI 10.1038/s41467-020-20670-7, PubMed 33563959
6. Eide M, Zhang X, Karlsen OA, Goldstone JV, Stegeman J, Jonassen I, Goksøyr A (2021)
   The chemical defensome of five model teleost fish
   Sci Rep, 11 (1), 10546
   DOI 10.1038/s41598-021-89948-0, PubMed 34006915
7. Eide PW, Moosavi SH, Eilertsen IA, Brunsell TH, Langerud J, Berg KCG, Røsok BI, Bjørnbeth BA, Nesbakken A, Lothe RA, Sveen A (2021)
   Metastatic heterogeneity of the consensus molecular subtypes of colorectal cancer
   NPJ Genom Med, 6 (1), 59
   DOI 10.1038/s41525-021-00223-7, PubMed 34262039
8. Gansmo LB, Sofiyeva N, Bjørnslett M, Romundstad P, Hveem K, Vatten L, Dørum A, Lønning PE, Knappskog S (2021)
   Impact of the APOBEC3A/B deletion polymorphism on risk of ovarian cancer
   Sci Rep, 11 (1), 23463
   DOI 10.1038/s41598-021-02820-z, PubMed 34873230
9. Helwa R, Gansmo LB, Bjørnslett M, Halle MK, Werner HMJ, Romundstad P, Hveem K, Vatten L, Dørum A, Lønning PE, Knappskog S (2021)
   Impact of MDM2 promoter SNP55 (rs2870820) on risk of endometrial and ovarian cancer
   Biomarkers, 26 (4), 302-308
   DOI 10.1080/1354750X.2021.1891291, PubMed 33645339
10. Kidd SG, Carm KT, Bogaard M, Olsen LG, Bakken AC, Løvf M, Lothe RA, Axcrona K, Axcrona U, Skotheim RI (2021)
    High expression of SCHLAP1 in primary prostate cancer is an independent predictor of biochemical recurrence, despite substantial heterogeneity
    Neoplasia, 23 (6), 634-641
    DOI 10.1016/j.neo.2021.05.012, PubMed 34107378
11. Kryeziu K, Moosavi SH, Bergsland CH, Guren MG, Eide PW, Totland MZ, Lassen K, Abildgaard A, Nesbakken A, Sveen A, Lothe RA (2021)
    Increased sensitivity to SMAC mimetic LCL161 identified by longitudinal ex vivo pharmacogenomics of recurrent, KRAS mutated rectal cancer liver metastases
    J Transl Med, 19 (1), 384
    DOI 10.1186/s12967-021-03062-3, PubMed 34496878
12. Moosavi SH, Eide PW, Eilertsen IA, Brunsell TH, Berg KCG, Røsok BI, Brudvik KW, Bjørnbeth BA, Guren MG, Nesbakken A, Lothe RA, Sveen A (2021)
    De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity
    Genome Med, 13 (1), 143
    DOI 10.1186/s13073-021-00956-1, PubMed 34470666
13. Pluta J, Pyle LC, Nead KT, Wilf R, Li M, Mitra N, Weathers B, D'Andrea K, Almstrup K, Anson-Cartwright L, Benitez J, Brown CD, Chanock S, Chen C, Cortessis VK, Ferlin A, Foresta C, Gamulin M, Gietema JA, Grasso C, Greene MH, Grotmol T, Hamilton RJ, Haugen TB, Hauser R et al. (2021)
    Identification of 22 susceptibility loci associated with testicular germ cell tumors
    Nat Commun, 12 (1), 4487
    DOI 10.1038/s41467-021-24334-y, PubMed 34301922
14. Slørdahl KS, Klotz D, Olsen JÅ, Skovlund E, Undseth C, Abildgaard HL, Brændengen M, Nesbakken A, Larsen SG, Hanekamp BA, Holmboe L, Tvedt R, Sveen A, Lothe RA, Malinen E, Kaasa S, Guren MG (2021)
    Treatment outcomes and prognostic factors after chemoradiotherapy for anal cancer
    Acta Oncol, 60 (7), 921-930
    DOI 10.1080/0284186X.2021.1918763, PubMed 33966592
15. Sveen A, Johannessen B, Eilertsen IA, Røsok BI, Gulla M, Eide PW, Bruun J, Kryeziu K, Meza-Zepeda LA, Myklebost O, Bjørnbeth BA, Skotheim RI, Nesbakken A, Lothe RA (2021)
    The expressed mutational landscape of microsatellite stable colorectal cancers
    Genome Med, 13 (1), 142
    DOI 10.1186/s13073-021-00955-2, PubMed 34470667
16. Tryggestad AMA, Axcrona K, Axcrona U, Bigalke I, Brennhovd B, Inderberg EM, Hønnåshagen TK, Skoge LJ, Solum G, Saebøe-Larssen S, Josefsen D, Olaussen RW, Aamdal S, Skotheim RI, Myklebust TÅ, Schendel DJ, Lilleby W, Dueland S, Kvalheim G (2021)
    Long-term first-in-man Phase I/II study of an adjuvant dendritic cell vaccine in patients with high-risk prostate cancer after radical prostatectomy
    Prostate, 82 (2), 245-253
    DOI 10.1002/pros.24267, PubMed 34762317
17. Vedeld HM, Grimsrud MM, Andresen K, Pharo HD, von Seth E, Karlsen TH, Honne H, Paulsen V, Färkkilä MA, Bergquist A, Jeanmougin M, Aabakken L, Boberg KM, Folseraas T, Lind GE (2021)
    Early and accurate detection of cholangiocarcinoma in patients with primary sclerosing cholangitis by methylation markers in bile
    Hepatology, 75 (1), 59-73
    DOI 10.1002/hep.32125, PubMed 34435693
18. Aasebø K, Bruun J, Bergsland CH, Nunes L, Eide GE, Pfeiffer P, Dahl O, Glimelius B, Lothe RA, Sorbye H (2021)
    Prognostic role of tumour-infiltrating lymphocytes and macrophages in relation to MSI, CDX2 and BRAF status: a population-based study of metastatic colorectal cancer patients
    Br J Cancer, 126 (1), 48-56
    DOI 10.1038/s41416-021-01586-5, PubMed 34671130

Publications 2020

1. Bergsland CH, Bruun J, Guren MG, Svindland A, Bjørnslett M, Smeby J, Hektoen M, Kolberg M, Domingo E, Pellinen T, Tomlinson I, Kerr D, Church DN, Nesbakken A, Sveen A, Lothe RA (2020)
   Prediction of relapse-free survival according to adjuvant chemotherapy and regulator of chromosome condensation 2 (RCC2) expression in colorectal cancer
   ESMO Open, 5 (6), e001040
   DOI 10.1136/esmoopen-2020-001040, PubMed 33219056
2. Bruun J, Kryeziu K, Eide PW, Moosavi SH, Eilertsen IA, Langerud J, Røsok B, Totland MZ, Brunsell TH, Pellinen T, Saarela J, Bergsland CH, Palmer HG, Brudvik KW, Guren T, Dienstmann R, Guren MG, Nesbakken A, Bjørnbeth BA, Sveen A, Lothe RA (2020)
   Patient-Derived Organoids from Multiple Colorectal Cancer Liver Metastases Reveal Moderate Intra-patient Pharmacotranscriptomic Heterogeneity
   Clin Cancer Res, 26 (15), 4107-4119
   DOI 10.1158/1078-0432.CCR-19-3637, PubMed 32299813
3. Flatin BTB, Vedeld HM, Pinto R, Langerud J, Lind GE, Lothe RA, Sveen A, Jeanmougin M (2020)
   Multiregional assessment of CIMP in primary colorectal cancers: Phenotype concordance but marker variability
   Int J Cancer, 148 (7), 1652-1657
   DOI 10.1002/ijc.33425, PubMed 33284993
4. Guldvik IJ, Zuber V, Braadland PR, Grytli HH, Ramberg H, Lilleby W, Thiede B, Zucknick M, Saatcioglu F, Gislefoss R, Kvåle R, George A, Grönberg H, Wiklund F, Neal DE, Gnanapragasam VJ, Taskén KA, Mills IG (2020)
   Identification and Validation of Leucine-rich α-2-glycoprotein 1 as a Noninvasive Biomarker for Improved Precision in Prostate Cancer Risk Stratification
   Eur Urol Open Sci, 21, 51-60
   DOI 10.1016/j.euros.2020.08.007, PubMed 34337468
5. Hoff AM, Kraggerud SM, Alagaratnam S, Berg KCG, Johannessen B, Høland M, Nilsen G, Lingjærde OC, Andrews PW, Lothe RA, Skotheim RI (2020)
   Frequent copy number gains of SLC2A3 and ETV1 in testicular embryonal carcinomas
   Endocr Relat Cancer, 27 (9), 457-468
   DOI 10.1530/ERC-20-0064, PubMed 32580154
6. Jeanmougin M, Håvik AB, Cekaite L, Brandal P, Sveen A, Meling TR, Ågesen TH, Scheie D, Heim S, Lothe RA, Lind GE (2020)
   Improved prognostication of glioblastoma beyond molecular subtyping by transcriptional profiling of the tumor microenvironment
   Mol Oncol, 14 (5), 1016-1027
   DOI 10.1002/1878-0261.12668, PubMed 32171051
7. Lopes N, Bergsland C, Bruun J, Bjørnslett M, Vieira AF, Mesquita P, Pinto R, Gomes R, Cavadas B, Bennett E, Pereira L, Lothe RA, Almeida R, David L (2020)
   A panel of intestinal differentiation markers (CDX2, GPA33, and LI-cadherin) identifies gastric cancer patients with favourable prognosis
   Gastric Cancer, 23 (5), 811-823
   DOI 10.1007/s10120-020-01064-6, PubMed 32215766
8. Smeby J, Kryeziu K, Berg KCG, Eilertsen IA, Eide PW, Johannessen B, Guren MG, Nesbakken A, Bruun J, Lothe RA, Sveen A (2020)
   Molecular correlates of sensitivity to PARP inhibition beyond homologous recombination deficiency in pre-clinical models of colorectal cancer point to wild-type TP53 activity
   EBioMedicine, 59, 102923
   DOI 10.1016/j.ebiom.2020.102923, PubMed 32799124
9. Vedeld HM, Folseraas T, Lind GE (2020)
   Detecting cholangiocarcinoma in patients with primary sclerosing cholangitis - The promise of DNA methylation and molecular biomarkers
   JHEP Rep, 2 (5), 100143
   DOI 10.1016/j.jhepr.2020.100143, PubMed 32939446
10. Wise JF, Nakken S, Steen CB, Vodák D, Trøen G, Johannessen B, Lingjærde OC, Hilden V, Blaker YN, Bai B, Aasheim LB, Pasanen A, Lorenz S, Sveen A, Lothe RA, Myklebost O, Leppä S, Meza-Zepeda LA, Beiske K, Lawrence MS, Hovig E, Myklebust JH, Smeland EB, Holte H (2020)
    Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series
    Blood Adv, 4 (9), 1859-1866
    DOI 10.1182/bloodadvances.2019001325, PubMed 32374878
11. Zhao S, Hoff AM, Skotheim RI (2020)
    ScaR-a tool for sensitive detection of known fusion transcripts: establishing prevalence of fusions in testicular germ cell tumors
    NAR Genom Bioinform, 2 (1), lqz025
    DOI 10.1093/nargab/lqz025, PubMed 33575572

Publications 2019

1. Berg KCG, Sveen A, Høland M, Alagaratnam S, Berg M, Danielsen SA, Nesbakken A, Søreide K, Lothe RA (2019)
   Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains
   Oncogene, 38 (33), 6109-6122
   DOI 10.1038/s41388-019-0868-5, PubMed 31308487
2. Brunsell TH, Cengija V, Sveen A, Bjørnbeth BA, Røsok BI, Brudvik KW, Guren MG, Lothe RA, Abildgaard A, Nesbakken A (2019)
   Heterogeneous radiological response to neoadjuvant therapy is associated with poor prognosis after resection of colorectal liver metastases
   Eur J Surg Oncol, 45 (12), 2340-2346
   DOI 10.1016/j.ejso.2019.07.017, PubMed 31350075
3. Brunsell TH, Sveen A, Bjørnbeth BA, Røsok BI, Danielsen SA, Brudvik KW, Berg KCG, Johannessen B, Cengija V, Abildgaard A, Guren MG, Nesbakken A, Lothe RA (2019)
   High Concordance and Negative Prognostic Impact of RAS/BRAF/PIK3CA Mutations in Multiple Resected Colorectal Liver Metastases
   Clin Colorectal Cancer, 19 (1), e26-e47
   DOI 10.1016/j.clcc.2019.09.003, PubMed 31982351
4. Burocziova M, Burdova K, Martinikova AS, Kasparek P, Kleiblova P, Danielsen SA, Borecka M, Jenikova G, Janečková L, Pavel J, Zemankova P, Schneiderova M, Schwarzova L, Ticha I, Sun XF, Jiraskova K, Liska V, Vodickova L, Vodicka P, Sedlacek R, Kleibl Z, Lothe RA, Korinek V, Macurek L (2019)
   Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon
   Cell Death Dis, 10 (11), 818
   DOI 10.1038/s41419-019-2057-4, PubMed 31659152
5. Carm KT, Hoff AM, Bakken AC, Axcrona U, Axcrona K, Lothe RA, Skotheim RI, Løvf M (2019)
   Interfocal heterogeneity challenges the clinical usefulness of molecular classification of primary prostate cancer
   Sci Rep, 9 (1), 13579
   DOI 10.1038/s41598-019-49964-7, PubMed 31537872
6. Dienstmann R, Villacampa G, Sveen A, Mason MJ, Niedzwiecki D, Nesbakken A, Moreno V, Warren RS, Lothe RA, Guinney J (2019)
   Relative contribution of clinicopathological variables, genomic markers, transcriptomic subtyping and microenvironment features for outcome prediction in stage II/III colorectal cancer
   Ann Oncol, 30 (10), 1622-1629
   DOI 10.1093/annonc/mdz287, PubMed 31504112
7. Eide PW, Eilertsen IA, Sveen A, Lothe RA (2019)
   Long noncoding RNA MIR31HG is a bona fide prognostic marker with colorectal cancer cell-intrinsic properties
   Int J Cancer, 144 (11), 2843-2853
   DOI 10.1002/ijc.31998, PubMed 30447009
8. Eilertsen IA, Moosavi SH, Strømme JM, Nesbakken A, Johannessen B, Lothe RA, Sveen A (2019)
   Technical differences between sequencing and microarray platforms impact transcriptomic subtyping of colorectal cancer
   Cancer Lett, 469, 246-255
   DOI 10.1016/j.canlet.2019.10.040, PubMed 31678167
9. Glaire MA, Domingo E, Sveen A, Bruun J, Nesbakken A, Nicholson G, Novelli M, Lawson K, Oukrif D, Kildal W, Danielsen HE, Kerr R, Kerr D, Tomlinson I, Lothe RA, Church DN (2019)
   Tumour-infiltrating CD8⁺ lymphocytes and colorectal cancer recurrence by tumour and nodal stage
   Br J Cancer, 121 (6), 474-482
   DOI 10.1038/s41416-019-0540-4, PubMed 31388185
10. Glaire MA, Domingo E, Sveen A, Bruun J, Nesbakken A, Nicholson G, Novelli M, Lawson K, Oukrif D, Kildal W, Danielsen HE, Kerr R, Kerr D, Tomlinson I, Lothe RA, Church DN (2019)
    Correction: Tumour-infiltrating CD8⁺ lymphocytes and colorectal cancer recurrence by tumour and nodal stage
    Br J Cancer, 121 (9), 807
    DOI 10.1038/s41416-019-0590-7, PubMed 31548598
11. Joranger P, Nesbakken A, Sorbye H, Hoff G, Oshaug A, Aas E (2019)
    Survival and costs of colorectal cancer treatment and effects of changing treatment strategies: a model approach
    Eur J Health Econ, 21 (3), 321-334
    DOI 10.1007/s10198-019-01130-6, PubMed 31707584
12. Kryeziu K, Bruun J, Guren TK, Sveen A, Lothe RA (2019)
    Combination therapies with HSP90 inhibitors against colorectal cancer
    Biochim Biophys Acta Rev Cancer, 1871 (2), 240-247
    DOI 10.1016/j.bbcan.2019.01.002, PubMed 30708039
13. Larsen LK, Lind GE, Guldberg P, Dahl C (2019)
    DNA-Methylation-Based Detection of Urological Cancer in Urine: Overview of Biomarkers and Considerations on Biomarker Design, Source of DNA, and Detection Technologies
    Int J Mol Sci, 20 (11)
    DOI 10.3390/ijms20112657, PubMed 31151158
14. Lopes N, Bergsland CH, Bjørnslett M, Pellinen T, Svindland A, Nesbakken A, Almeida R, Lothe RA, David L, Bruun J (2019)
    Digital image analysis of multiplex fluorescence IHC in colorectal cancer recognizes the prognostic value of CDX2 and its negative correlation with SOX2
    Lab Invest, 100 (1), 120-134
    DOI 10.1038/s41374-019-0336-4, PubMed 31641225
15. Marcuello M, Vymetalkova V, Neves RPL, Duran-Sanchon S, Vedeld HM, Tham E, van Dalum G, Flügen G, Garcia-Barberan V, Fijneman RJ, Castells A, Vodicka P, Lind GE, Stoecklein NH, Heitzer E, Gironella M (2019)
    Circulating biomarkers for early detection and clinical management of colorectal cancer
    Mol Aspects Med, 69, 107-122
    DOI 10.1016/j.mam.2019.06.002, PubMed 31189073
16. Miranda A, Hamilton PT, Zhang AW, Pattnaik S, Becht E, Mezheyeuski A, Bruun J, Micke P, de Reynies A, Nelson BH (2019)
    Cancer stemness, intratumoral heterogeneity, and immune response across cancers
    Proc Natl Acad Sci U S A, 116 (18), 9020-9029
    DOI 10.1073/pnas.1818210116, PubMed 30996127
17. Neckmann U, Wolowczyk C, Hall M, Almaas E, Ren J, Zhao S, Johannessen B, Skotheim RI, Bjørkøy G, Ten Dijke P, Holien T (2019)
    GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients
    Cell Commun Signal, 17 (1), 140
    DOI 10.1186/s12964-019-0467-7, PubMed 31694641
18. Røsok BI, Høst-Brunsell T, Brudvik KW, Carling U, Dorenberg E, Björnsson B, Lothe RA, Bjørnbeth BA, Sandström P (2019)
    Characterization of early recurrences following liver resection by ALPPS and two stage hepatectomy in patients with colorectal liver-metastases and small future liver remnants; a translational substudy of the LIGRO-RCT
    HPB (Oxford), 21 (8), 1017-1023
    DOI 10.1016/j.hpb.2018.12.003, PubMed 30765198
19. Smeby J, Sveen A, Bergsland CH, Eilertsen IA, Danielsen SA, Eide PW, Hektoen M, Guren MG, Nesbakken A, Bruun J, Lothe RA (2019)
    Exploratory analyses of consensus molecular subtype-dependent associations of TP53 mutations with immunomodulation and prognosis in colorectal cancer
    ESMO Open, 4 (3), e000523
    DOI 10.1136/esmoopen-2019-000523, PubMed 31321083
20. Smeby J, Sveen A, Eilertsen IA, Danielsen SA, Hoff AM, Eide PW, Johannessen B, Hektoen M, Skotheim RI, Guren MG, Nesbakken A, Lothe RA (2019)
    Transcriptional and functional consequences of TP53 splice mutations in colorectal cancer
    Oncogenesis, 8 (6), 35
    DOI 10.1038/s41389-019-0141-3, PubMed 31092812
21. Sveen A, Cremolini C, Dienstmann R (2019)
    Predictive modeling in colorectal cancer: time to move beyond consensus molecular subtypes
    Ann Oncol, 30 (11), 1682-1685
    DOI 10.1093/annonc/mdz412, PubMed 31868904
22. Sveen A, Kopetz S, Lothe RA (2019)
    Biomarker-guided therapy for colorectal cancer: strength in complexity
    Nat Rev Clin Oncol, 17 (1), 11-32
    DOI 10.1038/s41571-019-0241-1, PubMed 31289352
23. Totland MZ, Rasmussen NL, Knudsen LM, Leithe E (2019)
    Regulation of gap junction intercellular communication by connexin ubiquitination: physiological and pathophysiological implications
    Cell Mol Life Sci, 77 (4), 573-591
    DOI 10.1007/s00018-019-03285-0, PubMed 31501970
24. Aasen T, Leithe E, Graham SV, Kameritsch P, Mayán MD, Mesnil M, Pogoda K, Tabernero A (2019)
    Connexins in cancer: bridging the gap to the clinic
    Oncogene, 38 (23), 4429-4451
    DOI 10.1038/s41388-019-0741-6, PubMed 30814684

Publications 2018

1. Bruun J, Sveen A, Barros R, Eide PW, Eilertsen I, Kolberg M, Pellinen T, David L, Svindland A, Kallioniemi O, Guren MG, Nesbakken A, Almeida R, Lothe RA (2018)
   Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer
   Mol Oncol, 12 (9), 1639-1655
   DOI 10.1002/1878-0261.12347, PubMed 29900672
2. Celestino R, Nome T, Pestana A, Hoff AM, Gonçalves AP, Pereira L, Cavadas B, Eloy C, Bjøro T, Sobrinho-Simões M, Skotheim RI, Soares P (2018)
   CRABP1, C1QL1 and LCN2 are biomarkers of differentiated thyroid carcinoma, and predict extrathyroidal extension
   BMC Cancer, 18 (1), 68
   DOI 10.1186/s12885-017-3948-3, PubMed 29321030
3. Danielsen HE, Hveem TS, Domingo E, Pradhan M, Kleppe A, Syvertsen RA, Kostolomov I, Nesheim JA, Askautrud HA, Nesbakken A, Lothe RA, Svindland A, Shepherd N, Novelli M, Johnstone E, Tomlinson I, Kerr R, Kerr DJ (2018)
   Prognostic markers for colorectal cancer: estimating ploidy and stroma
   Ann Oncol, 29 (3), 616-623
   DOI 10.1093/annonc/mdx794, PubMed 29293881
4. Eilertsen IA, Sveen A, Strømme JM, Skotheim RI, Nesbakken A, Lothe RA (2018)
   Alternative splicing expands the prognostic impact of KRAS in microsatellite stable primary colorectal cancer
   Int J Cancer, 144 (4), 841-847
   DOI 10.1002/ijc.31809, PubMed 30121958
5. Gleditsch D, Wexels WA, Nesbakken A (2018)
   Surgical options and trends in treating rectal prolapse: long-term results in a 19-year follow-up study
   Langenbecks Arch Surg, 403 (8), 991-998
   DOI 10.1007/s00423-018-1728-4, PubMed 30415286
6. Høland M, Kolberg M, Danielsen SA, Bjerkehagen B, Eilertsen IA, Hektoen M, Mandahl N, van den Berg E, Smeland S, Mertens F, Sundby Hall K, Picci P, Sveen A, Lothe RA (2018)
   Inferior survival for patients with malignant peripheral nerve sheath tumors defined by aberrant TP53
   Mod Pathol, 31 (11), 1694-1707
   DOI 10.1038/s41379-018-0074-y, PubMed 29946184
7. Kleppe A, Albregtsen F, Vlatkovic L, Pradhan M, Nielsen B, Hveem TS, Askautrud HA, Kristensen GB, Nesbakken A, Trovik J, Wæhre H, Tomlinson I, Shepherd NA, Novelli M, Kerr DJ, Danielsen HE (2018)
   Chromatin organisation and cancer prognosis: a pan-cancer study
   Lancet Oncol, 19 (3), 356-369
   DOI 10.1016/S1470-2045(17)30899-9, PubMed 29402700
8. Lønning PE, Berge EO, Bjørnslett M, Minsaas L, Chrisanthar R, Høberg-Vetti H, Dulary C, Busato F, Bjørneklett S, Eriksen C, Kopperud R, Axcrona U, Davidson B, Bjørge L, Evans G, Howell A, Salvesen HB, Janszky I, Hveem K, Romundstad PR, Vatten LJ, Tost J, Dørum A, Knappskog S (2018)
   White Blood Cell BRCA1 Promoter Methylation Status and Ovarian Cancer Risk
   Ann Intern Med, 168 (5), 326-334
   DOI 10.7326/M17-0101, PubMed 29335712
9. Løvf M, Zhao S, Axcrona U, Johannessen B, Bakken AC, Carm KT, Hoff AM, Myklebost O, Meza-Zepeda LA, Lie AK, Axcrona K, Lothe RA, Skotheim RI (2018)
   Multifocal Primary Prostate Cancer Exhibits High Degree of Genomic Heterogeneity
   Eur Urol, 75 (3), 498-505
   DOI 10.1016/j.eururo.2018.08.009, PubMed 30181068
10. Mezheyeuski A, Bergsland CH, Backman M, Djureinovic D, Sjöblom T, Bruun J, Micke P (2018)
    Multispectral imaging for quantitative and compartment-specific immune infiltrates reveals distinct immune profiles that classify lung cancer patients
    J Pathol, 244 (4), 421-431
    DOI 10.1002/path.5026, PubMed 29282718
11. Oltedal S, Kørner H, Aasprong OG, Hussain I, Tjensvoll K, Smaaland R, Søreide JA, Søreide K, Lothe RA, Heikkilä R, Gilje B, Nordgård O (2018)
    The Prognostic Relevance of Sentinel Lymph Node Metastases Assessed by PHGR1 mRNA Quantification in Stage I to III Colon Cancer
    Transl Oncol, 11 (2), 436-443
    DOI 10.1016/j.tranon.2018.01.015, PubMed 29475140
12. Ommundsen N, Nesbakken A, Wyller TB, Skovlund E, Bakka AO, Jordhøy MS, Rostoft S (2018)
    Post-discharge complications in frail older patients after surgery for colorectal cancer
    Eur J Surg Oncol, 44 (10), 1542-1547
    DOI 10.1016/j.ejso.2018.06.024, PubMed 30037638
13. Ommundsen N, Wyller TB, Nesbakken A, Bakka AO, Jordhøy MS, Skovlund E, Rostoft S (2018)
    Preoperative geriatric assessment and tailored interventions in frail older patients with colorectal cancer: a randomized controlled trial
    Colorectal Dis, 20 (1), 16-25
    DOI 10.1111/codi.13785, PubMed 28649755
14. Ommundsen N, Wyller TB, Nesbakken A, Bakka AO, Jordhøy MS, Skovlund E, Rostoft S (2018)
    Reply to Lawday et al
    Colorectal Dis, 20 (4), 350-351
    DOI 10.1111/codi.14059, PubMed 29502337
15. Pharo HD, Andresen K, Berg KCG, Lothe RA, Jeanmougin M, Lind GE (2018)
    A robust internal control for high-precision DNA methylation analyses by droplet digital PCR
    Clin Epigenetics, 10, 24
    DOI 10.1186/s13148-018-0456-5, PubMed 29484034
16. Pinto D, Pinto C, Guerra J, Pinheiro M, Santos R, Vedeld HM, Yohannes Z, Peixoto A, Santos C, Pinto P, Lopes P, Lothe R, Lind GE, Henrique R, Teixeira MR (2018)
    Contribution of MLH1 constitutional methylation for Lynch syndrome diagnosis in patients with tumor MLH1 downregulation
    Cancer Med, 7 (2), 433-444
    DOI 10.1002/cam4.1285, PubMed 29341452
17. Rajpert-De Meyts E, Skotheim RI (2018)
    Complex Polygenic Nature of Testicular Germ Cell Cancer Suggests Multifactorial Aetiology
    Eur Urol, 73 (6), 832-833
    DOI 10.1016/j.eururo.2018.02.023, PubMed 29530636
18. Smeby J, Sveen A, Merok MA, Danielsen SA, Eilertsen IA, Guren MG, Dienstmann R, Nesbakken A, Lothe RA (2018)
    CMS-dependent prognostic impact of KRAS and BRAFV600E mutations in primary colorectal cancer
    Ann Oncol, 29 (5), 1227-1234
    DOI 10.1093/annonc/mdy085, PubMed 29518181
19. Vedeld HM, Nesbakken A, Lothe RA, Lind GE (2018)
    Re-assessing ZNF331 as a DNA methylation biomarker for colorectal cancer
    Clin Epigenetics, 10, 70
    DOI 10.1186/s13148-018-0503-2, PubMed 29854011
20. Viswanathan SR, Ha G, Hoff AM, Wala JA, Carrot-Zhang J, Whelan CW, Haradhvala NJ, Freeman SS, Reed SC, Rhoades J, Polak P, Cipicchio M, Wankowicz SA, Wong A, Kamath T, Zhang Z, Gydush GJ, Rotem D, PCF/SU2C International Prostate Cancer Dream Team, Love JC, Getz G, Gabriel S, Zhang CZ, Dehm SM, Nelson PS et al. (2018)
    Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing
    Cell, 174 (2), 433-447.e19
    DOI 10.1016/j.cell.2018.05.036, PubMed 29909985

Publications 2017

1. Barfeld SJ, Urbanucci A, Itkonen HM, Fazli L, Hicks JL, Thiede B, Rennie PS, Yegnasubramanian S, DeMarzo AM, Mills IG (2017)
   c-Myc Antagonises the Transcriptional Activity of the Androgen Receptor in Prostate Cancer Affecting Key Gene Networks
   EBioMedicine, 18, 83-93
   DOI 10.1016/j.ebiom.2017.04.006, PubMed 28412251
2. Berg KCG, Eide PW, Eilertsen IA, Johannessen B, Bruun J, Danielsen SA, Bjørnslett M, Meza-Zepeda LA, Eknæs M, Lind GE, Myklebost O, Skotheim RI, Sveen A, Lothe RA (2017)
   Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies
   Mol Cancer, 16 (1), 116
   DOI 10.1186/s12943-017-0691-y, PubMed 28683746
3. Dienstmann R, Mason MJ, Sinicrope FA, Phipps AI, Tejpar S, Nesbakken A, Danielsen SA, Sveen A, Buchanan DD, Clendenning M, Rosty C, Bot B, Alberts SR, Milburn Jessup J, Lothe RA, Delorenzi M, Newcomb PA, Sargent D, Guinney J (2017)
   Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study
   Ann Oncol, 28 (5), 1023-1031
   DOI 10.1093/annonc/mdx052, PubMed 28453697
4. Dukic AR, Haugen LH, Pidoux G, Leithe E, Bakke O, Taskén K (2017)
   A protein kinase A-ezrin complex regulates connexin 43 gap junction communication in liver epithelial cells
   Cell Signal, 32, 1-11
   DOI 10.1016/j.cellsig.2017.01.008, PubMed 28077322
5. Eide PW, Bruun J, Lothe RA, Sveen A (2017)
   CMScaller: an R package for consensus molecular subtyping of colorectal cancer pre-clinical models
   Sci Rep, 7 (1), 16618
   DOI 10.1038/s41598-017-16747-x, PubMed 29192179
6. Gansmo LB, Bjørnslett M, Halle MK, Salvesen HB, Romundstad P, Hveem K, Vatten L, Dørum A, Lønning PE, Knappskog S (2017)
   MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk
   BMC Cancer, 17 (1), 97
   DOI 10.1186/s12885-017-3094-y, PubMed 28158999
7. Itkonen HM, Brown M, Urbanucci A, Tredwell G, Ho Lau C, Barfeld S, Hart C, Guldvik IJ, Takhar M, Heemers HV, Erho N, Bloch K, Davicioni E, Derua R, Waelkens E, Mohler JL, Clarke N, Swinnen JV, Keun HC, Rekvig OP, Mills IG (2017)
   Lipid degradation promotes prostate cancer cell survival
   Oncotarget, 8 (24), 38264-38275
   DOI 10.18632/oncotarget.16123, PubMed 28415728
8. Kivinummi K, Urbanucci A, Leinonen K, Tammela TLJ, Annala M, Isaacs WB, Bova GS, Nykter M, Visakorpi T (2017)
   The expression of AURKA is androgen regulated in castration-resistant prostate cancer
   Sci Rep, 7 (1), 17978
   DOI 10.1038/s41598-017-18210-3, PubMed 29269934
9. Kolberg M, Bruun J, Murumägi A, Mpindi JP, Bergsland CH, Høland M, Eilertsen IA, Danielsen SA, Kallioniemi O, Lothe RA (2017)
   Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors
   Mol Oncol, 11 (9), 1156-1171
   DOI 10.1002/1878-0261.12086, PubMed 28556483
10. Labori KJ, Guren MG, Brudvik KW, Røsok BI, Waage A, Nesbakken A, Larsen S, Dueland S, Edwin B, Bjørnbeth BA (2017)
    Resection of synchronous liver metastases between radiotherapy and definitive surgery for locally advanced rectal cancer: short-term surgical outcomes, overall survival and recurrence-free survival
    Colorectal Dis, 19 (8), 731-738
    DOI 10.1111/codi.13622, PubMed 28181384
11. Landskron J, Kraggerud SM, Wik E, Dørum A, Bjørnslett M, Melum E, Helland Ø, Bjørge L, Lothe RA, Salvesen HB, Taskén K (2017)
    C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease
    PLoS One, 12 (7), e0182030
    DOI 10.1371/journal.pone.0182030, PubMed 28759630
12. Leithe E, Mesnil M, Aasen T (2017)
    The connexin 43 C-terminus: A tail of many tales
    Biochim Biophys Acta Biomembr, 1860 (1), 48-64
    DOI 10.1016/j.bbamem.2017.05.008, PubMed 28526583
13. Lind GE, Guriby M, Ahlquist T, Hussain I, Jeanmougin M, Søreide K, Kørner H, Lothe RA, Nordgård O (2017)
    Prognostic relevance of an epigenetic biomarker panel in sentinel lymph nodes from colon cancer patients
    Clin Epigenetics, 9, 97
    DOI 10.1186/s13148-017-0397-4, PubMed 28878843
14. Lind GE, van Engeland M (2017)
    Details matter: the role of genomic location and assay standardization in DNA methylation analyses
    Epigenomics, 9 (7), 933-935
    DOI 10.2217/epi-2017-0053, PubMed 28617096
15. Lågstad S, Zhao S, Hoff AM, Johannessen B, Lingjærde OC, Skotheim RI (2017)
    chimeraviz: a tool for visualizing chimeric RNA
    Bioinformatics, 33 (18), 2954-2956
    DOI 10.1093/bioinformatics/btx329, PubMed 28525538
16. Mesnil M, Aasen T, Boucher J, Chépied A, Cronier L, Defamie N, Kameritsch P, Laird DW, Lampe PD, Lathia JD, Leithe E, Mehta PP, Monvoisin A, Pogoda K, Sin WC, Tabernero A, Yamasaki H, Yeh ES, Dagli MLZ, Naus CC (2017)
    An update on minding the gap in cancer
    Biochim Biophys Acta Biomembr, 1860 (1), 237-243
    DOI 10.1016/j.bbamem.2017.06.015, PubMed 28655619
17. Smebye ML, Agostini A, Johannessen B, Thorsen J, Davidson B, Tropé CG, Heim S, Skotheim RI, Micci F (2017)
    Involvement of DPP9 in gene fusions in serous ovarian carcinoma
    BMC Cancer, 17 (1), 642
    DOI 10.1186/s12885-017-3625-6, PubMed 28893231
18. Solheim O, Førsund M, Tropé CG, Kraggerud SM, Nesland JM, Davidson B (2017)
    Epithelial-mesenchymal transition markers in malignant ovarian germ cell tumors
    APMIS, 125 (9), 781-786
    DOI 10.1111/apm.12715, PubMed 28585395
19. Sveen A, Bruun J, Eide PW, Eilertsen IA, Ramirez L, Murumägi A, Arjama M, Danielsen SA, Kryeziu K, Elez E, Tabernero J, Guinney J, Palmer HG, Nesbakken A, Kallioniemi O, Dienstmann R, Lothe RA (2017)
    Colorectal Cancer Consensus Molecular Subtypes Translated to Preclinical Models Uncover Potentially Targetable Cancer Cell Dependencies
    Clin Cancer Res, 24 (4), 794-806
    DOI 10.1158/1078-0432.CCR-17-1234, PubMed 29242316
20. Sveen A, Johannessen B, Tengs T, Danielsen SA, Eilertsen IA, Lind GE, Berg KCG, Leithe E, Meza-Zepeda LA, Domingo E, Myklebost O, Kerr D, Tomlinson I, Nesbakken A, Skotheim RI, Lothe RA (2017)
    Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1
    Genome Med, 9 (1), 46
    DOI 10.1186/s13073-017-0434-0, PubMed 28539123
21. Totland MZ, Bergsland CH, Fykerud TA, Knudsen LM, Rasmussen NL, Eide PW, Yohannes Z, Sørensen V, Brech A, Lothe RA, Leithe E (2017)
    The E3 ubiquitin ligase NEDD4 induces endocytosis and lysosomal sorting of connexin 43 to promote loss of gap junctions
    J Cell Sci, 130 (17), 2867-2882
    DOI 10.1242/jcs.202408, PubMed 28733455
22. Urbanucci A, Barfeld SJ, Kytölä V, Itkonen HM, Coleman IM, Vodák D, Sjöblom L, Sheng X, Tolonen T, Minner S, Burdelski C, Kivinummi KK, Kohvakka A, Kregel S, Takhar M, Alshalalfa M, Davicioni E, Erho N, Lloyd P, Karnes RJ, Ross AE, Schaeffer EM, Vander Griend DJ, Knapp S, Corey E et al. (2017)
    Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer
    Cell Rep, 19 (10), 2045-2059
    DOI 10.1016/j.celrep.2017.05.049, PubMed 28591577
23. Urbanucci A, Mills IG (2017)
    Bromodomain-containing proteins in prostate cancer
    Mol Cell Endocrinol, 462 (Pt A), 31-40
    DOI 10.1016/j.mce.2017.06.007, PubMed 28624514
24. Vedeld HM, Goel A, Lind GE (2017)
    Epigenetic biomarkers in gastrointestinal cancers: The current state and clinical perspectives
    Semin Cancer Biol, 51, 36-49
    DOI 10.1016/j.semcancer.2017.12.004, PubMed 29253542
25. Vedeld HM, Merok M, Jeanmougin M, Danielsen SA, Honne H, Presthus GK, Svindland A, Sjo OH, Hektoen M, Eknaes M, Nesbakken A, Lothe RA, Lind GE (2017)
    CpG island methylator phenotype identifies high risk patients among microsatellite stable BRAF mutated colorectal cancers
    Int J Cancer, 141 (5), 967-976
    DOI 10.1002/ijc.30796, PubMed 28542846
26. Zhao S, Løvf M, Carm KT, Bakken AC, Hoff AM, Skotheim RI (2017)
    Novel transcription-induced fusion RNAs in prostate cancer
    Oncotarget, 8 (30), 49133-49143
    DOI 10.18632/oncotarget.17099, PubMed 28467780
27. Zuber V, Bettella F, Witoelar A, PRACTICAL Consortium, CRUK GWAS, BCAC Consortium, TRICL Consortium, Andreassen OA, Mills IG, Urbanucci A (2017)
    Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer
    BMC Genomics, 18 (1), 270
    DOI 10.1186/s12864-017-3620-y, PubMed 28359301

Publications 2016

1. Banales JM, Cardinale V, Carpino G, Marzioni M, Andersen JB, Invernizzi P, Lind GE, Folseraas T, Forbes SJ, Fouassier L, Geier A, Calvisi DF, Mertens JC, Trauner M, Benedetti A, Maroni L, Vaquero J, Macias RI, Raggi C, Perugorria MJ, Gaudio E, Boberg KM, Marin JJ, Alvaro D (2016)
   Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)
   Nat Rev Gastroenterol Hepatol, 13 (5), 261-80
   DOI 10.1038/nrgastro.2016.51, PubMed 27095655
2. Barfeld SJ, Mills IG (2016)
   Mapping Protein-DNA Interactions Using ChIP-exo and Illumina-Based Sequencing
   Methods Mol Biol, 1443, 119-37
   DOI 10.1007/978-1-4939-3724-0_8, PubMed 27246337
3. Boye K, Jacob H, Frikstad KA, Nesland JM, Maelandsmo GM, Dahl O, Nesbakken A, Flatmark K (2016)
   Prognostic significance of S100A4 expression in stage II and III colorectal cancer: results from a population-based series and a randomized phase III study on adjuvant chemotherapy
   Cancer Med, 5 (8), 1840-9
   DOI 10.1002/cam4.766, PubMed 27273130
4. Cekaite L, Eide PW, Lind GE, Skotheim RI, Lothe RA (2016)
   MicroRNAs as growth regulators, their function and biomarker status in colorectal cancer
   Oncotarget, 7 (6), 6476-505
   DOI 10.18632/oncotarget.6390, PubMed 26623728
5. Domingo E, Freeman-Mills L, Rayner E, Glaire M, Briggs S, Vermeulen L, Fessler E, Medema JP, Boot A, Morreau H, van Wezel T, Liefers GJ, Lothe RA, Danielsen SA, Sveen A, Nesbakken A, Zlobec I, Lugli A, Koelzer VH, Berger MD, Castellví-Bel S, Muñoz J, Epicolon consortium, de Bruyn M, Nijman HW et al. (2016)
   Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study
   Lancet Gastroenterol Hepatol, 1 (3), 207-216
   DOI 10.1016/S2468-1253(16)30014-0, PubMed 28404093
6. Fiorito E, Sharma Y, Gilfillan S, Wang S, Singh SK, Satheesh SV, Katika MR, Urbanucci A, Thiede B, Mills IG, Hurtado A (2016)
   CTCF modulates Estrogen Receptor function through specific chromatin and nuclear matrix interactions
   Nucleic Acids Res, 44 (22), 10588-10602
   DOI 10.1093/nar/gkw785, PubMed 27638884
7. Fykerud TA, Knudsen LM, Totland MZ, Sørensen V, Dahal-Koirala S, Lothe RA, Brech A, Leithe E (2016)
   Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding
   Cell Cycle, 15 (21), 2943-2957
   DOI 10.1080/15384101.2016.1231280, PubMed 27625181
8. Gansmo LB, Bjørnslett M, Halle MK, Salvesen HB, Dørum A, Birkeland E, Hveem K, Romundstad P, Vatten L, Lønning PE, Knappskog S (2016)
   The MDM4 SNP34091 (rs4245739) C-allele is associated with increased risk of ovarian-but not endometrial cancer
   Tumour Biol, 37 (8), 10697-702
   DOI 10.1007/s13277-016-4940-2, PubMed 26867771
9. Gao J, Zhao S, Halstensen TS (2016)
   Increased interleukin-6 expression is associated with poor prognosis and acquired cisplatin resistance in head and neck squamous cell carcinoma
   Oncol Rep, 35 (6), 3265-74
   DOI 10.3892/or.2016.4765, PubMed 27108527
10. Gerner L, Munack S, Temmerman K, Lawrence-Dörner AM, Besir H, Wilmanns M, Jensen JK, Thiede B, Mills IG, Morth JP (2016)
    Using the fluorescent properties of STO-609 as a tool to assist structure-function analyses of recombinant CaMKK2
    Biochem Biophys Res Commun, 476 (2), 102-7
    DOI 10.1016/j.bbrc.2016.05.045, PubMed 27178209
11. Gerner L, Munack S, Temmerman K, Lawrence-Dörner AM, Besir H, Wilmanns M, Jensen JK, Thiede B, Mills IG, Morth JP (2016)
    Data for the co-expression and purification of human recombinant CaMKK2 in complex with calmodulin in Escherichia coli
    Data Brief, 8, 733-40
    DOI 10.1016/j.dib.2016.06.033, PubMed 27508226
12. Gleditsch D, Søreide OK, Nesbakken A (2016)
    Managing Malignant Colorectal Obstruction with Self-Expanding Stents. A Closer Look at Bowel Perforations and Failed Procedures
    J Gastrointest Surg, 20 (9), 1643-9
    DOI 10.1007/s11605-016-3186-z, PubMed 27342437
13. Itkonen HM, Gorad SS, Duveau DY, Martin SE, Barkovskaya A, Bathen TF, Moestue SA, Mills IG (2016)
    Inhibition of O-GlcNAc transferase activity reprograms prostate cancer cell metabolism
    Oncotarget, 7 (11), 12464-76
    DOI 10.18632/oncotarget.7039, PubMed 26824323
14. Leithe E (2016)
    Regulation of connexins by the ubiquitin system: Implications for intercellular communication and cancer
    Biochim Biophys Acta, 1865 (2), 133-46
    DOI 10.1016/j.bbcan.2016.02.001, PubMed 26855059
15. Lorenz S, Barøy T, Sun J, Nome T, Vodák D, Bryne JC, Håkelien AM, Fernandez-Cuesta L, Möhlendick B, Rieder H, Szuhai K, Zaikova O, Ahlquist TC, Thomassen GO, Skotheim RI, Lothe RA, Tarpey PS, Campbell P, Flanagan A, Myklebost O, Meza-Zepeda LA (2016)
    Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations
    Oncotarget, 7 (5), 5273-88
    DOI 10.18632/oncotarget.6567, PubMed 26672768
16. Massie CE, Mills IG, Lynch AG (2016)
    The importance of DNA methylation in prostate cancer development
    J Steroid Biochem Mol Biol, 166, 1-15
    DOI 10.1016/j.jsbmb.2016.04.009, PubMed 27117390
17. McNair C, Urbanucci A, Comstock CE, Augello MA, Goodwin JF, Launchbury R, Zhao SG, Schiewer MJ, Ertel A, Karnes J, Davicioni E, Wang L, Wang Q, Mills IG, Feng FY, Li W, Carroll JS, Knudsen KE (2016)
    Cell cycle-coupled expansion of AR activity promotes cancer progression
    Oncogene, 36 (12), 1655-1668
    DOI 10.1038/onc.2016.334, PubMed 27669432
18. Moen LV, Ramberg H, Zhao S, Grytli HH, Sveen A, Berge V, Skotheim RI, Taskén KA, Skålhegg BS (2016)
    Observed correlation between the expression levels of catalytic subunit, Cβ2, of cyclic adenosine monophosphate-dependent protein kinase and prostate cancer aggressiveness
    Urol Oncol, 35 (3), 111.e1-111.e8
    DOI 10.1016/j.urolonc.2016.10.002, PubMed 27838142
19. Munkley J, Mills IG, Elliott DJ (2016)
    The role of glycans in the development and progression of prostate cancer
    Nat Rev Urol, 13 (6), 324-33
    DOI 10.1038/nrurol.2016.65, PubMed 27091662
20. Munkley J, Vodak D, Livermore KE, James K, Wilson BT, Knight B, Mccullagh P, Mcgrath J, Crundwell M, Harries LW, Leung HY, Robson CN, Mills IG, Rajan P, Elliott DJ (2016)
    Glycosylation is an Androgen-Regulated Process Essential for Prostate Cancer Cell Viability
    EBioMedicine, 8, 103-116
    DOI 10.1016/j.ebiom.2016.04.018, PubMed 27428423
21. Pharo HD, Honne H, Vedeld HM, Dahl C, Andresen K, Liestøl K, Jeanmougin M, Guldberg P, Lind GE (2016)
    Experimental factors affecting the robustness of DNA methylation analysis
    Sci Rep, 6, 33936
    DOI 10.1038/srep33936, PubMed 27671843
22. Ramalho-Carvalho J, Martins JB, Cekaite L, Sveen A, Torres-Ferreira J, Graça I, Costa-Pinheiro P, Eilertsen IA, Antunes L, Oliveira J, Lothe RA, Henrique R, Jerónimo C (2016)
    Epigenetic disruption of miR-130a promotes prostate cancer by targeting SEC23B and DEPDC1
    Cancer Lett, 385, 150-159
    DOI 10.1016/j.canlet.2016.10.028, PubMed 27984115
23. Ramberg H, Grytli HH, Nygård S, Wang W, Ögren O, Zhao S, Løvf M, Katz B, Skotheim RI, Bjartell A, Eri LM, Berge V, Svindland A, Taskén KA (2016)
    PBX3 is a putative biomarker of aggressive prostate cancer
    Int J Cancer, 139 (8), 1810-20
    DOI 10.1002/ijc.30220, PubMed 27273830
24. Ross-Adams H, Ball S, Lawrenson K, Halim S, Russell R, Wells C, Strand SH, Ørntoft TF, Larson M, Armasu S, Massie CE, Asim M, Mortensen MM, Borre M, Woodfine K, Warren AY, Lamb AD, Kay J, Whitaker H, Ramos-Montoya A, Murrell A, Sørensen KD, Fridley BL, Goode EL, Gayther SA et al. (2016)
    HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer
    Oncotarget, 7 (46), 74734-74746
    DOI 10.18632/oncotarget.12543, PubMed 27732966
25. Rønning B, Wyller TB, Nesbakken A, Skovlund E, Jordhøy MS, Bakka A, Rostoft S (2016)
    Quality of life in older and frail patients after surgery for colorectal cancer-A follow-up study
    J Geriatr Oncol, 7 (3), 195-200
    DOI 10.1016/j.jgo.2016.03.002, PubMed 27067579
26. Smebye ML, Haugom L, Davidson B, Trope CG, Heim S, Skotheim RI, Micci F (2016)
    Bilateral ovarian carcinomas differ in the expression of metastasis-related genes
    Oncol Lett, 13 (1), 184-190
    DOI 10.3892/ol.2016.5384, PubMed 28123539
27. Stornes T, Wibe A, Nesbakken A, Myklebust TÅ, Endreseth BH (2016)
    National Early Rectal Cancer Treatment Revisited
    Dis Colon Rectum, 59 (7), 623-9
    DOI 10.1097/DCR.0000000000000591, PubMed 27270514
28. Sveen A, Løes IM, Alagaratnam S, Nilsen G, Høland M, Lingjærde OC, Sorbye H, Berg KC, Horn A, Angelsen JH, Knappskog S, Lønning PE, Lothe RA (2016)
    Intra-patient Inter-metastatic Genetic Heterogeneity in Colorectal Cancer as a Key Determinant of Survival after Curative Liver Resection
    PLoS Genet, 12 (7), e1006225
    DOI 10.1371/journal.pgen.1006225, PubMed 27472274
29. Tekpli X, Urbanucci A, Hashim A, Vågbø CB, Lyle R, Kringen MK, Staff AC, Dybedal I, Mills IG, Klungland A, Staerk J (2016)
    Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells
    Epigenetics Chromatin, 9, 21
    DOI 10.1186/s13072-016-0070-8, PubMed 27252783
30. Whitington T, Gao P, Song W, Ross-Adams H, Lamb AD, Yang Y, Svezia I, Klevebring D, Mills IG, Karlsson R, Halim S, Dunning MJ, Egevad L, Warren AY, Neal DE, Grönberg H, Lindberg J, Wei GH, Wiklund F (2016)
    Gene regulatory mechanisms underpinning prostate cancer susceptibility
    Nat Genet, 48 (4), 387-97
    DOI 10.1038/ng.3523, PubMed 26950096

Publications 2015

1. Andreassen OA, Desikan RS, Wang Y, Thompson WK, Schork AJ, Zuber V, Doncheva NT, Ellinghaus E, Albrecht M, Mattingsdal M, Franke A, Lie BA, Mills IG, Aukrust P, McEvoy LK, Djurovic S, Karlsen TH, Dale AM (2015)
   Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms
   PLoS One, 10 (4), e0123057
   DOI 10.1371/journal.pone.0123057, PubMed 25853426
2. Andresen K, Boberg KM, Vedeld HM, Honne H, Jebsen P, Hektoen M, Wadsworth CA, Clausen OP, Lundin KE, Paulsen V, Foss A, Mathisen Ø, Aabakken L, Schrumpf E, Lothe RA, Lind GE (2015)
   Four DNA methylation biomarkers in biliary brush samples accurately identify the presence of cholangiocarcinoma
   Hepatology, 61 (5), 1651-9
   DOI 10.1002/hep.27707, PubMed 25644509
3. Asim M, Massie CE, Orafidiya F, Pértega-Gomes N, Warren AY, Esmaeili M, Selth LA, Zecchini HI, Luko K, Qureshi A, Baridi A, Menon S, Madhu B, Escriu C, Lyons S, Vowler SL, Zecchini VR, Shaw G, Hessenkemper W, Russell R, Mohammed H, Stefanos N, Lynch AG, Grigorenko E, D'Santos C et al. (2015)
   Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target
   J Natl Cancer Inst, 108 (5)
   DOI 10.1093/jnci/djv371, PubMed 26657335
4. Barfeld SJ, Fazli L, Persson M, Marjavaara L, Urbanucci A, Kaukoniemi KM, Rennie PS, Ceder Y, Chabes A, Visakorpi T, Mills IG (2015)
   Myc-dependent purine biosynthesis affects nucleolar stress and therapy response in prostate cancer
   Oncotarget, 6 (14), 12587-602
   DOI 10.18632/oncotarget.3494, PubMed 25869206
5. Bjørnslett M, Dahl AA, Sørebø Ø, Dørum A (2015)
   Psychological distress related to BRCA testing in ovarian cancer patients
   Fam Cancer, 14 (4), 495-504
   DOI 10.1007/s10689-015-9811-2, PubMed 25980896
6. Bollineni RC, Guldvik IJ, Grönberg H, Wiklund F, Mills IG, Thiede B (2015)
   A differential protein solubility approach for the depletion of highly abundant proteins in plasma using ammonium sulfate
   Analyst, 140 (24), 8109-17
   DOI 10.1039/c5an01560j, PubMed 26541119
7. Brabrand S, Johannessen B, Axcrona U, Kraggerud SM, Berg KG, Bakken AC, Bruun J, Fosså SD, Lothe RA, Lehne G, Skotheim RI (2015)
   Exome sequencing of bilateral testicular germ cell tumors suggests independent development lineages
   Neoplasia, 17 (2), 167-74
   DOI 10.1016/j.neo.2014.12.005, PubMed 25748235
8. Bruun J, Kolberg M, Ahlquist TC, Røyrvik EC, Nome T, Leithe E, Lind GE, Merok MA, Rognum TO, Bjørkøy G, Johansen T, Lindblom A, Sun XF, Svindland A, Liestøl K, Nesbakken A, Skotheim RI, Lothe RA (2015)
   Regulator of Chromosome Condensation 2 Identifies High-Risk Patients within Both Major Phenotypes of Colorectal Cancer
   Clin Cancer Res, 21 (16), 3759-70
   DOI 10.1158/1078-0432.CCR-14-3294, PubMed 25910952
9. Du H, Liang Z, Zhao S, Nan MG, Tran LS, Lu K, Huang YB, Li JN (2015)
   The Evolutionary History of R2R3-MYB Proteins Across 50 Eukaryotes: New Insights Into Subfamily Classification and Expansion
   Sci Rep, 5, 11037
   DOI 10.1038/srep11037, PubMed 26047035
10. Guren MG, Kørner H, Pfeffer F, Myklebust TÅ, Eriksen MT, Edna TH, Larsen SG, Knudsen KO, Nesbakken A, Wasmuth HH, Vonen B, Hofsli E, Færden AE, Brændengen M, Dahl O, Steigen SE, Johansen MJ, Lindsetmo RO, Drolsum A, Tollåli G, Dørum LM, Møller B, Wibe A (2015)
    Nationwide improvement of rectal cancer treatment outcomes in Norway, 1993-2010
    Acta Oncol, 54 (10), 1714-22
    DOI 10.3109/0284186X.2015.1034876, PubMed 25924970
11. Hoff AM, Alagaratnam S, Zhao S, Bruun J, Andrews PW, Lothe RA, Skotheim RI (2015)
    Identification of Novel Fusion Genes in Testicular Germ Cell Tumors
    Cancer Res, 76 (1), 108-16
    DOI 10.1158/0008-5472.CAN-15-1790, PubMed 26659575
12. Hoff AM, Johannessen B, Alagaratnam S, Zhao S, Nome T, Løvf M, Bakken AC, Hektoen M, Sveen A, Lothe RA, Skotheim RI (2015)
    Novel RNA variants in colorectal cancers
    Oncotarget, 6 (34), 36587-602
    DOI 10.18632/oncotarget.5500, PubMed 26474385
13. Johannessen B, Sveen A, Skotheim RI (2015)
    TIN: An R Package for Transcriptome Instability Analysis
    Cancer Inform, 14, 109-12
    DOI 10.4137/CIN.S31363, PubMed 26448683
14. Khanna A, Rane JK, Kivinummi KK, Urbanucci A, Helenius MA, Tolonen TT, Saramäki OR, Latonen L, Manni V, Pimanda JE, Maitland NJ, Westermarck J, Visakorpi T (2015)
    CIP2A is a candidate therapeutic target in clinically challenging prostate cancer cell populations
    Oncotarget, 6 (23), 19661-70
    DOI 10.18632/oncotarget.3875, PubMed 25965834
15. Kolberg M, Høland M, Lind GE, Ågesen TH, Skotheim RI, Hall KS, Mandahl N, Smeland S, Mertens F, Davidson B, Lothe RA (2015)
    Protein expression of BIRC5, TK1, and TOP2A in malignant peripheral nerve sheath tumours--A prognostic test after surgical resection
    Mol Oncol, 9 (6), 1129-39
    DOI 10.1016/j.molonc.2015.02.005, PubMed 25769404
16. Kumar S, Krabberød AK, Neumann RS, Michalickova K, Zhao S, Zhang X, Shalchian-Tabrizi K (2015)
    BIR Pipeline for Preparation of Phylogenomic Data
    Evol Bioinform Online, 11, 79-83
    DOI 10.4137/EBO.S10189, PubMed 25987827
17. Lund K, Dembinski JL, Solberg N, Urbanucci A, Mills IG, Krauss S (2015)
    Slug-dependent upregulation of L1CAM is responsible for the increased invasion potential of pancreatic cancer cells following long-term 5-FU treatment
    PLoS One, 10 (4), e0123684
    DOI 10.1371/journal.pone.0123684, PubMed 25860483
18. Mesquita D, Barros-Silva JD, Santos J, Skotheim RI, Lothe RA, Paulo P, Teixeira MR (2015)
    Specific and redundant activities of ETV1 and ETV4 in prostate cancer aggressiveness revealed by co-overexpression cellular contexts
    Oncotarget, 6 (7), 5217-36
    DOI 10.18632/oncotarget.2847, PubMed 25595908
19. Mills IG (2015)
    Molecular subtyping of prostate cancer: a partnership model
    Eur Urol, 68 (4), 568-9
    DOI 10.1016/j.eururo.2015.05.012, PubMed 26001612
20. Munkley J, Oltean S, Vodák D, Wilson BT, Livermore KE, Zhou Y, Star E, Floros VI, Johannessen B, Knight B, McCullagh P, McGrath J, Crundwell M, Skotheim RI, Robson CN, Leung HY, Harries LW, Rajan P, Mills IG, Elliott DJ (2015)
    The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer
    Oncotarget, 6 (33), 34358-74
    DOI 10.18632/oncotarget.6024, PubMed 26452038
21. Pickard A, Mills IG (2015)
    Maintaining a Healthy Balance: Targeting TERT to Stem Benign Prostatic Hyperplasia
    Eur Urol, 69 (4), 555-556
    DOI 10.1016/j.eururo.2015.10.028, PubMed 26520704
22. Ross-Adams H, Lamb AD, Dunning MJ, Halim S, Lindberg J, Massie CM, Egevad LA, Russell R, Ramos-Montoya A, Vowler SL, Sharma NL, Kay J, Whitaker H, Clark J, Hurst R, Gnanapragasam VJ, Shah NC, Warren AY, Cooper CS, Lynch AG, Stark R, Mills IG, Grönberg H, Neal DE, CamCaP Study Group (2015)
    Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study
    EBioMedicine, 2 (9), 1133-44
    DOI 10.1016/j.ebiom.2015.07.017, PubMed 26501111
23. Rounge TB, Furu K, Skotheim RI, Haugen TB, Grotmol T, Enerly E (2015)
    Profiling of the small RNA populations in human testicular germ cell tumors shows global loss of piRNAs
    Mol Cancer, 14, 153
    DOI 10.1186/s12943-015-0411-4, PubMed 26265322
24. Seglen PO, Luhr M, Mills IG, Sætre F, Szalai P, Engedal N (2015)
    Macroautophagic cargo sequestration assays
    Methods, 75, 25-36
    DOI 10.1016/j.ymeth.2014.12.021, PubMed 25576638
25. Sevilla LM, Latorre V, Carceller E, Boix J, Vodák D, Mills IG, Pérez P (2015)
    Glucocorticoid receptor and Klf4 co-regulate anti-inflammatory genes in keratinocytes
    Mol Cell Endocrinol, 412, 281-9
    DOI 10.1016/j.mce.2015.05.015, PubMed 26001834
26. Shaw GL, Whitaker H, Corcoran M, Dunning MJ, Luxton H, Kay J, Massie CE, Miller JL, Lamb AD, Ross-Adams H, Russell R, Nelson AW, Eldridge MD, Lynch AG, Ramos-Montoya A, Mills IG, Taylor AE, Arlt W, Shah N, Warren AY, Neal DE (2015)
    The Early Effects of Rapid Androgen Deprivation on Human Prostate Cancer
    Eur Urol, 70 (2), 214-8
    DOI 10.1016/j.eururo.2015.10.042, PubMed 26572708
27. Sheng X, Arnoldussen YJ, Storm M, Tesikova M, Nenseth HZ, Zhao S, Fazli L, Rennie P, Risberg B, Wæhre H, Danielsen H, Mills IG, Jin Y, Hotamisligil G, Saatcioglu F (2015)
    Divergent androgen regulation of unfolded protein response pathways drives prostate cancer
    EMBO Mol Med, 7 (6), 788-801
    DOI 10.15252/emmm.201404509, PubMed 25864123
28. Sveen A, Kilpinen S, Ruusulehto A, Lothe RA, Skotheim RI (2015)
    Aberrant RNA splicing in cancer; expression changes and driver mutations of splicing factor genes
    Oncogene, 35 (19), 2413-27
    DOI 10.1038/onc.2015.318, PubMed 26300000
29. Szalai P, Hagen LK, Sætre F, Luhr M, Sponheim M, Øverbye A, Mills IG, Seglen PO, Engedal N (2015)
    Autophagic bulk sequestration of cytosolic cargo is independent of LC3, but requires GABARAPs
    Exp Cell Res, 333 (1), 21-38
    DOI 10.1016/j.yexcr.2015.02.003, PubMed 25684710

Publications 2014

1. Almeida M, Costa VL, Costa NR, Ramalho-Carvalho J, Baptista T, Ribeiro FR, Paulo P, Teixeira MR, Oliveira J, Lothe RA, Lind GE, Henrique R, Jerónimo C (2014)
   Epigenetic regulation of EFEMP1 in prostate cancer: biological relevance and clinical potential
   J Cell Mol Med, 18 (11), 2287-97
   DOI 10.1111/jcmm.12394, PubMed 25211630
2. Andreassen OA, Zuber V, Thompson WK, Schork AJ, Bettella F, PRACTICAL Consortium, CRUK GWAS, Djurovic S, Desikan RS, Mills IG, Dale AM (2014)
   Shared common variants in prostate cancer and blood lipids
   Int J Epidemiol, 43 (4), 1205-14
   DOI 10.1093/ije/dyu090, PubMed 24786909
3. Barfeld SJ, East P, Zuber V, Mills IG (2014)
   Meta-analysis of prostate cancer gene expression data identifies a novel discriminatory signature enriched for glycosylating enzymes
   BMC Med Genomics, 7, 513
   DOI 10.1186/s12920-014-0074-9, PubMed 25551447
4. Barfeld SJ, Itkonen HM, Urbanucci A, Mills IG (2014)
   Androgen-regulated metabolism and biosynthesis in prostate cancer
   Endocr Relat Cancer, 21 (4), T57-66
   DOI 10.1530/ERC-13-0515, PubMed 24497572
5. Bethge N, Honne H, Andresen K, Hilden V, Trøen G, Liestøl K, Holte H, Delabie J, Lind GE, Smeland EB (2014)
   A gene panel, including LRP12, is frequently hypermethylated in major types of B-cell lymphoma
   PLoS One, 9 (9), e104249
   DOI 10.1371/journal.pone.0104249, PubMed 25226156
6. Bon H, Wadhwa K, Schreiner A, Osborne M, Carroll T, Ramos-Montoya A, Ross-Adams H, Visser M, Hoffmann R, Ahmed AA, Neal DE, Mills IG (2014)
   Salt-inducible kinase 2 regulates mitotic progression and transcription in prostate cancer
   Mol Cancer Res, 13 (4), 620-635
   DOI 10.1158/1541-7786.MCR-13-0182-T, PubMed 25548099
7. Bruun J, Kolberg M, Nesland JM, Svindland A, Nesbakken A, Lothe RA (2014)
   Prognostic Significance of β-Catenin, E-Cadherin, and SOX9 in Colorectal Cancer: Results from a Large Population-Representative Series
   Front Oncol, 4, 118
   DOI 10.3389/fonc.2014.00118, PubMed 24904831
8. Danielsen SA, Eide PW, Nesbakken A, Guren T, Leithe E, Lothe RA (2014)
   Portrait of the PI3K/AKT pathway in colorectal cancer
   Biochim Biophys Acta, 1855 (1), 104-21
   DOI 10.1016/j.bbcan.2014.09.008, PubMed 25450577
9. Danielsen SA, Lind GE, Kolberg M, Høland M, Bjerkehagen B, Sundby Hall K, van den Berg E, Mertens F, Smeland S, Picci P, Lothe RA (2014)
   Methylated RASSF1A in malignant peripheral nerve sheath tumors identifies neurofibromatosis type 1 patients with inferior prognosis
   Neuro Oncol, 17 (1), 63-9
   DOI 10.1093/neuonc/nou140, PubMed 25038505
10. Engedal N, Mills IG (2014)
    Endosomal signaling and oncogenesis
    Methods Enzymol, 535, 179-200
    DOI 10.1016/B978-0-12-397925-4.00012-2, PubMed 24377925
11. Hveem TS, Merok MA, Pretorius ME, Novelli M, Bævre MS, Sjo OH, Clinch N, Liestøl K, Svindland A, Lothe RA, Nesbakken A, Danielsen HE (2014)
    Prognostic impact of genomic instability in colorectal cancer
    Br J Cancer, 110 (8), 2159-64
    DOI 10.1038/bjc.2014.133, PubMed 24642618
12. Itkonen HM, Engedal N, Babaie E, Luhr M, Guldvik IJ, Minner S, Hohloch J, Tsourlakis MC, Schlomm T, Mills IG (2014)
    UAP1 is overexpressed in prostate cancer and is protective against inhibitors of N-linked glycosylation
    Oncogene, 34 (28), 3744-50
    DOI 10.1038/onc.2014.307, PubMed 25241896
13. Joranger P, Nesbakken A, Hoff G, Sorbye H, Oshaug A, Aas E (2014)
    Modeling and validating the cost and clinical pathway of colorectal cancer
    Med Decis Making, 35 (2), 255-65
    DOI 10.1177/0272989X14544749, PubMed 25073464
14. Løvf M, Nome T, Bruun J, Eknaes M, Bakken AC, Mpindi JP, Kilpinen S, Rognum TO, Nesbakken A, Kallioniemi O, Lothe RA, Skotheim RI (2014)
    A novel transcript, VNN1-AB, as a biomarker for colorectal cancer
    Int J Cancer, 135 (9), 2077-84
    DOI 10.1002/ijc.28855, PubMed 24687856
15. Mills IG (2014)
    HOXB13, RFX6 and prostate cancer risk
    Nat Genet, 46 (2), 94-5
    DOI 10.1038/ng.2881, PubMed 24473320
16. Mills IG (2014)
    Maintaining and reprogramming genomic androgen receptor activity in prostate cancer
    Nat Rev Cancer, 14 (3), 187-98
    DOI 10.1038/nrc3678, PubMed 24561445
17. Nome T, Hoff AM, Bakken AC, Rognum TO, Nesbakken A, Skotheim RI (2014)
    High frequency of fusion transcripts involving TCF7L2 in colorectal cancer: novel fusion partner and splice variants
    PLoS One, 9 (3), e91264
    DOI 10.1371/journal.pone.0091264, PubMed 24608966
18. Oppelt A, Haugsten EM, Zech T, Danielsen HE, Sveen A, Lobert VH, Skotheim RI, Wesche J (2014)
    PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1
    Biochem J, 461 (3), 383-90
    DOI 10.1042/BJ20140132, PubMed 24840251
19. Ramos-Montoya A, Lamb AD, Russell R, Carroll T, Jurmeister S, Galeano-Dalmau N, Massie CE, Boren J, Bon H, Theodorou V, Vias M, Shaw GL, Sharma NL, Ross-Adams H, Scott HE, Vowler SL, Howat WJ, Warren AY, Wooster RF, Mills IG, Neal DE (2014)
    HES6 drives a critical AR transcriptional programme to induce castration-resistant prostate cancer through activation of an E2F1-mediated cell cycle network
    EMBO Mol Med, 6 (5), 651-61
    DOI 10.1002/emmm.201303581, PubMed 24737870
20. Sharma NL, Massie CE, Butter F, Mann M, Bon H, Ramos-Montoya A, Menon S, Stark R, Lamb AD, Scott HE, Warren AY, Neal DE, Mills IG (2014)
    The ETS family member GABPα modulates androgen receptor signalling and mediates an aggressive phenotype in prostate cancer
    Nucleic Acids Res, 42 (10), 6256-69
    DOI 10.1093/nar/gku281, PubMed 24753418
21. Sirnes S, Lind GE, Bruun J, Fykerud TA, Mesnil M, Lothe RA, Rivedal E, Kolberg M, Leithe E (2014)
    Connexins in colorectal cancer pathogenesis
    Int J Cancer, 137 (1), 1-11
    DOI 10.1002/ijc.28911, PubMed 24752574
22. Smebye ML, Sveen A, Haugom L, Davidson B, Tropé CG, Lothe RA, Heim S, Skotheim RI, Micci F (2014)
    Chromosome 19 rearrangements in ovarian carcinomas: zinc finger genes are particularly targeted
    Genes Chromosomes Cancer, 53 (7), 558-67
    DOI 10.1002/gcc.22166, PubMed 24634323
23. Sveen A, Johannessen B, Teixeira MR, Lothe RA, Skotheim RI (2014)
    Transcriptome instability as a molecular pan-cancer characteristic of carcinomas
    BMC Genomics, 15 (1), 672
    DOI 10.1186/1471-2164-15-672, PubMed 25109687
24. Søndenaa K, Quirke P, Hohenberger W, Sugihara K, Kobayashi H, Kessler H, Brown G, Tudyka V, D'Hoore A, Kennedy RH, West NP, Kim SH, Heald R, Storli KE, Nesbakken A, Moran B (2014)
    The rationale behind complete mesocolic excision (CME) and a central vascular ligation for colon cancer in open and laparoscopic surgery : proceedings of a consensus conference
    Int J Colorectal Dis, 29 (4), 419-28
    DOI 10.1007/s00384-013-1818-2, PubMed 24477788
25. Sørlie T, Johnsen H, Vu P, Lind GE, Lothe R, Børresen-Dale AL (2014)
    Mutation screening of the TP53 gene by temporal temperature gel electrophoresis (TTGE)
    Methods Mol Biol, 1105, 315-24
    DOI 10.1007/978-1-62703-739-6_25, PubMed 24623239
26. Vedeld HM, Andresen K, Eilertsen IA, Nesbakken A, Seruca R, Gladhaug IP, Thiis-Evensen E, Rognum TO, Boberg KM, Lind GE (2014)
    The novel colorectal cancer biomarkers CDO1, ZSCAN18 and ZNF331 are frequently methylated across gastrointestinal cancers
    Int J Cancer, 136 (4), 844-53
    DOI 10.1002/ijc.29039, PubMed 24948044
27. Vedeld HM, Skotheim RI, Lothe RA, Lind GE (2014)
    The recently suggested intestinal cancer stem cell marker DCLK1 is an epigenetic biomarker for colorectal cancer
    Epigenetics, 9 (3), 346-50
    DOI 10.4161/epi.27582, PubMed 24384857
28. Zecchini V, Madhu B, Russell R, Pértega-Gomes N, Warren A, Gaude E, Borlido J, Stark R, Ireland-Zecchini H, Rao R, Scott H, Boren J, Massie C, Asim M, Brindle K, Griffiths J, Frezza C, Neal DE, Mills IG (2014)
    Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer
    EMBO J, 33 (12), 1365-82
    DOI 10.15252/embj.201386874, PubMed 24837709

Publications 2013

1. Ahmed D, Eide PW, Eilertsen IA, Danielsen SA, Eknæs M, Hektoen M, Lind GE, Lothe RA (2013)
   Epigenetic and genetic features of 24 colon cancer cell lines
   Oncogenesis, 2 (9), e71
   DOI 10.1038/oncsis.2013.35, PubMed 24042735
2. Alagaratnam S, Harrison N, Bakken AC, Hoff AM, Jones M, Sveen A, Moore HD, Andrews PW, Lothe RA, Skotheim RI (2013)
   Transforming pluripotency: an exon-level study of malignancy-specific transcripts in human embryonal carcinoma and embryonic stem cells
   Stem Cells Dev, 22 (7), 1136-46
   DOI 10.1089/scd.2012.0369, PubMed 23137282
3. Avery S, Hirst AJ, Baker D, Lim CY, Alagaratnam S, Skotheim RI, Lothe RA, Pera MF, Colman A, Robson P, Andrews PW, Knowles BB (2013)
   BCL-XL mediates the strong selective advantage of a 20q11.21 amplification commonly found in human embryonic stem cell cultures
   Stem Cell Reports, 1 (5), 379-86
   DOI 10.1016/j.stemcr.2013.10.005, PubMed 24286026
4. Barros-Silva JD, Paulo P, Bakken AC, Cerveira N, Løvf M, Henrique R, Jerónimo C, Lothe RA, Skotheim RI, Teixeira MR (2013)
   Novel 5' fusion partners of ETV1 and ETV4 in prostate cancer
   Neoplasia, 15 (7), 720-6
   DOI 10.1593/neo.13232, PubMed 23814484
5. Berg M, Guriby M, Nordgård O, Nedrebø BS, Ahlquist TC, Smaaland R, Oltedal S, Søreide JA, Kørner H, Lothe RA, Søreide K (2013)
   Influence of microsatellite instability and KRAS and BRAF mutations on lymph node harvest in stage I-III colon cancers
   Mol Med, 19 (1), 286-93
   DOI 10.2119/molmed.2013.00049, PubMed 23979710
6. Bethge N, Honne H, Hilden V, Trøen G, Eknæs M, Liestøl K, Holte H, Delabie J, Smeland EB, Lind GE (2013)
   Identification of highly methylated genes across various types of B-cell non-hodgkin lymphoma
   PLoS One, 8 (11), e79602
   DOI 10.1371/journal.pone.0079602, PubMed 24260260
7. Bethge N, Lothe RA, Honne H, Andresen K, Trøen G, Eknæs M, Liestøl K, Holte H, Delabie J, Smeland EB, Lind GE (2013)
   Colorectal cancer DNA methylation marker panel validated with high performance in Non-Hodgkin lymphoma
   Epigenetics, 9 (3), 428-36
   DOI 10.4161/epi.27554, PubMed 24362313
8. Chung CC, Kanetsky PA, Wang Z, Hildebrandt MA, Koster R, Skotheim RI, Kratz CP, Turnbull C, Cortessis VK, Bakken AC, Bishop DT, Cook MB, Erickson RL, Fosså SD, Jacobs KB, Korde LA, Kraggerud SM, Lothe RA, Loud JT, Rahman N, Skinner EC, Thomas DC, Wu X, Yeager M, Schumacher FR et al. (2013)
   Meta-analysis identifies four new loci associated with testicular germ cell tumor
   Nat Genet, 45 (6), 680-5
   DOI 10.1038/ng.2634, PubMed 23666239
9. Engedal N, Torgersen ML, Guldvik IJ, Barfeld SJ, Bakula D, Sætre F, Hagen LK, Patterson JB, Proikas-Cezanne T, Seglen PO, Simonsen A, Mills IG (2013)
   Modulation of intracellular calcium homeostasis blocks autophagosome formation
   Autophagy, 9 (10), 1475-90
   DOI 10.4161/auto.25900, PubMed 23970164
10. Håvik AB, Lind GE, Honne H, Meling TR, Scheie D, Hall KS, van den Berg E, Mertens F, Picci P, Lothe RA, Heim S, Brandal P (2013)
    Sequencing IDH1/2 glioma mutation hotspots in gliomas and malignant peripheral nerve sheath tumors
    Neuro Oncol, 16 (2), 320-2
    DOI 10.1093/neuonc/not230, PubMed 24311631
11. Itkonen HM, Mills IG (2013)
    N-linked glycosylation supports cross-talk between receptor tyrosine kinases and androgen receptor
    PLoS One, 8 (5), e65016
    DOI 10.1371/journal.pone.0065016, PubMed 23724116
12. Itkonen HM, Minner S, Guldvik IJ, Sandmann MJ, Tsourlakis MC, Berge V, Svindland A, Schlomm T, Mills IG (2013)
    O-GlcNAc transferase integrates metabolic pathways to regulate the stability of c-MYC in human prostate cancer cells
    Cancer Res, 73 (16), 5277-87
    DOI 10.1158/0008-5472.CAN-13-0549, PubMed 23720054
13. Kraggerud SM, Hoei-Hansen CE, Alagaratnam S, Skotheim RI, Abeler VM, Rajpert-De Meyts E, Lothe RA (2013)
    Molecular characteristics of malignant ovarian germ cell tumors and comparison with testicular counterparts: implications for pathogenesis
    Endocr Rev, 34 (3), 339-76
    DOI 10.1210/er.2012-1045, PubMed 23575763
14. Løvf M, Thomassen GO, Mertens F, Cerveira N, Teixeira MR, Lothe RA, Skotheim RI (2013)
    Assessment of fusion gene status in sarcomas using a custom made fusion gene microarray
    PLoS One, 8 (8), e70649
    DOI 10.1371/journal.pone.0070649, PubMed 23967081
15. Mesquita B, Lopes P, Rodrigues A, Pereira D, Afonso M, Leal C, Henrique R, Lind GE, Jerónimo C, Lothe RA, Teixeira MR (2013)
    Frequent copy number gains at 1q21 and 1q32 are associated with overexpression of the ETS transcription factors ETV3 and ELF3 in breast cancer irrespective of molecular subtypes
    Breast Cancer Res Treat, 138 (1), 37-45
    DOI 10.1007/s10549-013-2408-2, PubMed 23329352
16. Nome T, Thomassen GO, Bruun J, Ahlquist T, Bakken AC, Hoff AM, Rognum T, Nesbakken A, Lorenz S, Sun J, Barros-Silva JD, Lind GE, Myklebost O, Teixeira MR, Meza-Zepeda LA, Lothe RA, Skotheim RI (2013)
    Common fusion transcripts identified in colorectal cancer cell lines by high-throughput RNA sequencing
    Transl Oncol, 6 (5), 546-53
    DOI 10.1593/tlo.13457, PubMed 24151535
17. Schumacher FR, Wang Z, Skotheim RI, Koster R, Chung CC, Hildebrandt MA, Kratz CP, Bakken AC, Bishop DT, Cook MB, Erickson RL, Fosså SD, Greene MH, Jacobs KB, Kanetsky PA, Kolonel LN, Loud JT, Korde LA, Le Marchand L, Lewinger JP, Lothe RA, Pike MC, Rahman N, Rubertone MV, Schwartz SM et al. (2013)
    Testicular germ cell tumor susceptibility associated with the UCK2 locus on chromosome 1q23
    Hum Mol Genet, 22 (13), 2748-53
    DOI 10.1093/hmg/ddt109, PubMed 23462292

Publications 2012

1. Agesen TH, Sveen A, Merok MA, Lind GE, Nesbakken A, Skotheim RI, Lothe RA (2012)
   ColoGuideEx: a robust gene classifier specific for stage II colorectal cancer prognosis
   Gut, 61 (11), 1560-7
   DOI 10.1136/gutjnl-2011-301179, PubMed 22213796
2. Ahmed D, Danielsen SA, Aagesen TH, Bretthauer M, Thiis-Evensen E, Hoff G, Rognum TO, Nesbakken A, Lothe RA, Lind GE (2012)
   A tissue-based comparative effectiveness analysis of biomarkers for early detection of colorectal tumors
   Clin Transl Gastroenterol, 3 (12), e27
   DOI 10.1038/ctg.2012.21, PubMed 23324654
3. Andresen K, Boberg KM, Vedeld HM, Honne H, Hektoen M, Wadsworth CA, Clausen OP, Karlsen TH, Foss A, Mathisen O, Schrumpf E, Lothe RA, Lind GE (2012)
   Novel target genes and a valid biomarker panel identified for cholangiocarcinoma
   Epigenetics, 7 (11), 1249-57
   DOI 10.4161/epi.22191, PubMed 22983262
4. Camões MJ, Paulo P, Ribeiro FR, Barros-Silva JD, Almeida M, Costa VL, Cerveira N, Skotheim RI, Lothe RA, Henrique R, Jerónimo C, Teixeira MR (2012)
   Potential downstream target genes of aberrant ETS transcription factors are differentially affected in Ewing's sarcoma and prostate carcinoma
   PLoS One, 7 (11), e49819
   DOI 10.1371/journal.pone.0049819, PubMed 23185447
5. Cekaite L, Rantala JK, Bruun J, Guriby M, Agesen TH, Danielsen SA, Lind GE, Nesbakken A, Kallioniemi O, Lothe RA, Skotheim RI (2012)
   MiR-9, -31, and -182 deregulation promote proliferation and tumor cell survival in colon cancer
   Neoplasia, 14 (9), 868-79
   DOI 10.1593/neo.121094, PubMed 23019418
6. Celestino R, Sigstad E, Løvf M, Thomassen GO, Grøholt KK, Jørgensen LH, Berner A, Castro P, Lothe RA, Bjøro T, Sobrinho-Simões M, Soares P, Skotheim RI (2012)
   Survey of 548 oncogenic fusion transcripts in thyroid tumors supports the importance of the already established thyroid fusions genes
   Genes Chromosomes Cancer, 51 (12), 1154-64
   DOI 10.1002/gcc.22003, PubMed 22961909
7. Eide PW, Cekaite L, Danielsen SA, Eilertsen IA, Kjenseth A, Fykerud TA, Ågesen TH, Bruun J, Rivedal E, Lothe RA, Leithe E (2012)
   NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway
   Cell Signal, 25 (1), 12-8
   DOI 10.1016/j.cellsig.2012.08.012, PubMed 22974840
8. Fykerud TA, Kjenseth A, Schink KO, Sirnes S, Bruun J, Omori Y, Brech A, Rivedal E, Leithe E (2012)
   Smad ubiquitination regulatory factor-2 controls gap junction intercellular communication by modulating endocytosis and degradation of connexin43
   J Cell Sci, 125 (Pt 17), 3966-76
   DOI 10.1242/jcs.093500, PubMed 22623726
9. Grisanzio C, Werner L, Takeda D, Awoyemi BC, Pomerantz MM, Yamada H, Sooriakumaran P, Robinson BD, Leung R, Schinzel AC, Mills I, Ross-Adams H, Neal DE, Kido M, Yamamoto T, Petrozziello G, Stack EC, Lis R, Kantoff PW, Loda M, Sartor O, Egawa S, Tewari AK, Hahn WC, Freedman ML (2012)
   Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis
   Proc Natl Acad Sci U S A, 109 (28), 11252-7
   DOI 10.1073/pnas.1200853109, PubMed 22730461
10. Hart LS, Cunningham JT, Datta T, Dey S, Tameire F, Lehman SL, Qiu B, Zhang H, Cerniglia G, Bi M, Li Y, Gao Y, Liu H, Li C, Maity A, Thomas-Tikhonenko A, Perl AE, Koong A, Fuchs SY, Diehl JA, Mills IG, Ruggero D, Koumenis C (2012)
    ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth
    J Clin Invest, 122 (12), 4621-34
    DOI 10.1172/JCI62973, PubMed 23143306
11. Håvik AB, Brandal P, Honne H, Dahlback HS, Scheie D, Hektoen M, Meling TR, Helseth E, Heim S, Lothe RA, Lind GE (2012)
    MGMT promoter methylation in gliomas-assessment by pyrosequencing and quantitative methylation-specific PCR
    J Transl Med, 10, 36
    DOI 10.1186/1479-5876-10-36, PubMed 22390413
12. Kjenseth A, Fykerud TA, Sirnes S, Bruun J, Yohannes Z, Kolberg M, Omori Y, Rivedal E, Leithe E (2012)
    The gap junction channel protein connexin 43 is covalently modified and regulated by SUMOylation
    J Biol Chem, 287 (19), 15851-61
    DOI 10.1074/jbc.M111.281832, PubMed 22411987
13. Kolberg M, Høland M, Agesen TH, Brekke HR, Liestøl K, Hall KS, Mertens F, Picci P, Smeland S, Lothe RA (2012)
    Survival meta-analyses for >1800 malignant peripheral nerve sheath tumor patients with and without neurofibromatosis type 1
    Neuro Oncol, 15 (2), 135-47
    DOI 10.1093/neuonc/nos287, PubMed 23161774
14. Kristjansson SR, Ronning B, Hurria A, Skovlund E, Jordhoy MS, Nesbakken A, Wyller TB (2012)
    A comparison of two pre-operative frailty measures in older surgical cancer patients
    J. Geriatr. Oncol., 3 (1), 1-7
    DOI 10.1016/j.jgo.2011.09.002
15. Lind GE, Ahmed D, Lothe RA (2012)
    Vimentin in upper gastrointestinal pathologies--letter
    Cancer Epidemiol Biomarkers Prev, 21 (10), 1889; author reply 1890
    DOI 10.1158/1055-9965.EPI-12-0894, PubMed 22929079
16. Lindberg J, Mills IG, Klevebring D, Liu W, Neiman M, Xu J, Wikström P, Wiklund P, Wiklund F, Egevad L, Grönberg H (2012)
    The mitochondrial and autosomal mutation landscapes of prostate cancer
    Eur Urol, 63 (4), 702-8
    DOI 10.1016/j.eururo.2012.11.053, PubMed 23265383
17. Lobert VH, Bruun J, Abrahamsen H, Lothe RA, Stenmark H, Kolberg M, Campsteijn C (2012)
    Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene β-catenin
    EMBO Rep, 14 (1), 10-1
    DOI 10.1038/embor.2012.188, PubMed 23229585
18. Matheu A, Collado M, Wise C, Manterola L, Cekaite L, Tye AJ, Canamero M, Bujanda L, Schedl A, Cheah KS, Skotheim RI, Lothe RA, López de Munain A, Briscoe J, Serrano M, Lovell-Badge R (2012)
    Oncogenicity of the developmental transcription factor Sox9
    Cancer Res, 72 (5), 1301-15
    DOI 10.1158/0008-5472.CAN-11-3660, PubMed 22246670
19. Merok MA, Ahlquist T, Røyrvik EC, Tufteland KF, Hektoen M, Sjo OH, Mala T, Svindland A, Lothe RA, Nesbakken A (2012)
    Microsatellite instability has a positive prognostic impact on stage II colorectal cancer after complete resection: results from a large, consecutive Norwegian series
    Ann Oncol, 24 (5), 1274-82
    DOI 10.1093/annonc/mds614, PubMed 23235802
20. Nordgård O, Oltedal S, Aasprong OG, Søreide JA, Søreide K, Tjensvoll K, Gilje B, Heikkilä R, Guriby M, Lothe RA, Smaaland R, Kørner H (2012)
    Prognostic relevance of occult metastases detected by cytokeratin 20 and mucin 2 mRNA levels in sentinel lymph nodes from colon cancer patients
    Ann Surg Oncol, 19 (12), 3719-26
    DOI 10.1245/s10434-012-2454-8, PubMed 22752373
21. Nyquist KB, Panagopoulos I, Thorsen J, Haugom L, Gorunova L, Bjerkehagen B, Fosså A, Guriby M, Nome T, Lothe RA, Skotheim RI, Heim S, Micci F (2012)
    Whole-transcriptome sequencing identifies novel IRF2BP2-CDX1 fusion gene brought about by translocation t(1;5)(q42;q32) in mesenchymal chondrosarcoma
    PLoS One, 7 (11), e49705
    DOI 10.1371/journal.pone.0049705, PubMed 23185413
22. Paulo P, Ribeiro FR, Santos J, Mesquita D, Almeida M, Barros-Silva JD, Itkonen H, Henrique R, Jerónimo C, Sveen A, Mills IG, Skotheim RI, Lothe RA, Teixeira MR (2012)
    Molecular subtyping of primary prostate cancer reveals specific and shared target genes of different ETS rearrangements
    Neoplasia, 14 (7), 600-11
    DOI 10.1593/neo.12600, PubMed 22904677
23. Sharma NL, Massie CE, Ramos-Montoya A, Zecchini V, Scott HE, Lamb AD, MacArthur S, Stark R, Warren AY, Mills IG, Neal DE (2012)
    The androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man
    Cancer Cell, 23 (1), 35-47
    DOI 10.1016/j.ccr.2012.11.010, PubMed 23260764
24. Sjo OH, Merok MA, Svindland A, Nesbakken A (2012)
    Prognostic impact of lymph node harvest and lymph node ratio in patients with colon cancer
    Dis Colon Rectum, 55 (3), 307-15
    DOI 10.1097/DCR.0b013e3182423f62, PubMed 22469798
25. Sveen A, Bakken AC, Ågesen TH, Lind GE, Nesbakken A, Nordgård O, Brackmann S, Rognum TO, Lothe RA, Skotheim RI (2012)
    The exon-level biomarker SLC39A14 has organ-confined cancer-specificity in colorectal cancer
    Int J Cancer, 131 (6), 1479-85
    DOI 10.1002/ijc.27399, PubMed 22173985
26. Sveen A, Ågesen TH, Nesbakken A, Meling GI, Rognum TO, Liestøl K, Skotheim RI, Lothe RA (2012)
    ColoGuidePro: a prognostic 7-gene expression signature for stage III colorectal cancer patients
    Clin Cancer Res, 18 (21), 6001-10
    DOI 10.1158/1078-0432.CCR-11-3302, PubMed 22991413