On December 21st, Anne Cathrine Bakken defended her master thesis "Exon-specific biomarkers in cancer: Experimental validation of exon microarray data from colorectal and testicular cancers". Anne Cathrine was successful in validating several novel RNA variants which are specific to cancer. Anne Cathrine is continuing the work as a research associate at the Genome biology group. The master project was supervised by Rolf Skotheim and Ragnhild A Lothe.
Nunes L, Li F, Wu M, Luo T, Hammarström K, Torell E, Ljuslinder I, Mezheyeuski A, Edqvist PH, Löfgren-Burström A, Zingmark C, Edin S, Larsson C, Mathot L, Osterman E, Osterlund E, Ljungström V, Neves I, Yacoub N, Guðnadóttir U, Birgisson H, Enblad M, Ponten F, Palmqvist R, Xu Xet al.(2024) Prognostic genome and transcriptome signatures in colorectal cancers Nature, 633(8028), 137-146 DOI 10.1038/s41586-024-07769-3, PubMed 39112715
Bogaard M, Strømme JM, Kidd SG, Johannessen B, Bakken AC, Lothe RA, Axcrona K, Skotheim RI, Axcrona U(2024) GRIN3A: A biomarker associated with a cribriform pattern and poor prognosis in prostate cancer Neoplasia, 55, 101023 DOI 10.1016/j.neo.2024.101023, PubMed 38944914
Langerud J, Eilertsen IA, Moosavi SH, Klokkerud SMK, Reims HM, Backe IF, Hektoen M, Sjo OH, Jeanmougin M, Tejpar S, Nesbakken A, Lothe RA, Sveen A(2024) Multiregional transcriptomics identifies congruent consensus subtypes with prognostic value beyond tumor heterogeneity of colorectal cancer Nat Commun, 15(1), 4342 DOI 10.1038/s41467-024-48706-2, PubMed 38773143