Anita Sveen

  • Project group leader, Assoc. professor; PhD
  • +47 2278 1719

Biosketch

Current positions

Project group leader in Computational Oncology & Assistant group leader in the Lothe lab.

Associate Professor, Inst. Clinical Medicine, Faculty of Medicine, University of Oslo.

Academic degrees

2012: PhD in cancer genomics, The Faculty of Medicine, University of Oslo, Norway.

2007: MSc in molecular biology, Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.

Areas of Research

Genomics and transcriptomics for precision therapy of colorectal cancer

Tumor heterogeneity modeling

Molecular prediction models for risk assessment and treatment benefit

Prices and Scholarships

2019: Early Career Award (Oslo University Hospital)

2019: Open Call research grant (Norwegian Cancer Society)

2018: Young Research Talent grant (Research Council of Norway)

2018: Postdoc grant (Regional Health Authority)

2017: Onkologisk Forum Young Investigator Award

2015: Personal researcher grant (Norwegian Cancer Society)

Most relevant publications

Sveen A, Kopetz S, Lothe RA. Biomarker-guided therapy for colorectal cancer: strength in complexity. Nat Rev Clin Oncol 2019; doi: 10.1038/s41571-019-0241-1.

› Smeby J, Sveen A, Merok MA, Danielsen SA, Eilertsen IA, Guren MG, Dienstmann R, Nesbakken A, Lothe RA. CMS-dependent prognostic impact of KRAS and BRAFV600E mutations in primary colorectal cancer. Ann Oncol 2018;29(5):1227-1234.

Sveen A, Bruun J, Eide PW, Eilertsen IA, Ramirez L, Murumägi A, Arjama M, Danielsen SA, Kryeziu K, Elez E, Tabernero J, Guinney J, Palmer HG, Nesbakken A, Kallioniemi O, Dienstmann R, Lothe RA. Colorectal cancer consensus molecular subtypes translated to preclinical models uncover potentially targetable cancer cell dependencies. Clin Cancer Res 2017;24(4):794-806.

Eide PW, Bruun J, Lothe RA, Sveen A. CMScaller: an R package for consensus molecular subtyping of colorectal cancer pre-clinical models. Sci Rep 2017;7(1):16618.

Sveen A, Johannessen B, Tengs T, Danielsen SA, Eilertsen IA, Lind GE, Berg KCG, Leithe E, Meza-Zepeda LA, Domingo E, Myklebost O, Kerr D, Tomlinson I, Nesbakken A, Skotheim RI, Lothe RA. Multilevel genomics of colorectal cancers with microsatellite instability - clinical impact of JAK1 mutations and consensus molecular subtype 1. Genome Med 2017;9(1):46.

Sveen A, Løes IM, Alagaratnam S, Nilsen G, Høland M, Lingjærde OC, Sorbye H, Berg KC, Horn A, Angelsen JH, Knappskog S, Lønning PE, Lothe RA. Intra-patient inter-metastatic genetic heterogeneity in colorectal cancer as a key determinant of survival after curative liver resection. PLoS Genet 2016;12(7):e1006225.

Sveen A, Kilpinen S, Ruusulehto A, Lothe RA, Skotheim RI. Aberrant RNA splicing in cancer; expression changes and driver mutations of splicing factor genes. Oncogene 2015;35(19):2413-27.

Agesen TH, Sveen A, Merok MA, Lind GE, Nesbakken A, Skotheim RI, Lothe RA. ColoGuideEx: a robust gene classifier specific for stage II colorectal cancer prognosis. Gut 2012;61(11):1560-7.

All publications

 
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