Light Meets Precision:
EIC Pathfinder Project SCALPEL Pioneering a Revolutionary Photoimmunotherapy for Cancer
Theo Theodossiou, Project coordinator
In a groundbreaking effort to revolutionise modern oncology, the SCALPEL project launches a Europe wide initiative aimed at redefining cancer treatment by using light to precisely ‘click’ tags to cancer cells, enabling the immune system to recognise and destroy them with unparalleled accuracy. Project coordinator is Theo Theodossiou, head of the Protonics project group at the Department of Radiation Biology at OUH.
The multidisciplinary initiative funded by the European Innovation Council Pathfinder programme under Horizon Europe with a total budget of more than EUR 4 million aims to revolutionise modern oncology offering new hope for millions worldwide.
From major journals, first or last author from the Institute for Cancer Research
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Berg K(2026) 40th anniversary of the European Society for photobiology : History and scientific significance Photochem Photobiol Sci(in press) DOI 10.1007/s43630-026-00937-6, PubMed 42406267
Lyngholm E, Stokkevåg CH, Karger CP, Sørensen BS, Overgaard CB, Lühr A, Juvkam IS, Malinen E, Ytre-Hauge KS(2026) Proton RBE for in vivo model systems: LET and dose dependencies for early and late biological endpoints Phys Med, 148, 105870(in press) DOI 10.1016/j.ejmp.2026.105870, PubMed 42398397